ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0008009 chemokine activity 11/408 45/18639 0.244444444444444 11.1671568627451 2.51458532277265e-09 1.92868694256662e-06 GO:0031625 ubiquitin protein ligase binding 24/408 302/18639 0.0794701986754967 3.63050253213868 5.9269546384582e-08 1.95305633287018e-05 GO:0043394 proteoglycan binding 9/408 37/18639 0.243243243243243 11.1122813990461 7.63907300992246e-08 1.95305633287018e-05 GO:0044389 ubiquitin-like protein ligase binding 24/408 322/18639 0.0745341614906832 3.40500548045305 1.96306638266781e-07 3.76417978876553e-05 GO:0042379 chemokine receptor binding 11/408 72/18639 0.152777777777778 6.97947303921569 4.40615458387119e-07 5.95779820820223e-05 GO:0042605 peptide antigen binding 9/408 45/18639 0.2 9.13676470588235 4.66059833757671e-07 5.95779820820223e-05 GO:0042277 peptide binding 19/408 249/18639 0.0763052208835341 3.48591424521616 2.63013776612804e-06 0.000288187952374316 GO:0042625 ATPase-coupled ion transmembrane transporter activity 6/408 24/18639 0.25 11.4209558823529 1.021634735439e-05 0.000783593842081713 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 6/408 24/18639 0.25 11.4209558823529 1.021634735439e-05 0.000783593842081713 GO:0046961 proton-transporting ATPase activity, rotational mechanism 6/408 24/18639 0.25 11.4209558823529 1.021634735439e-05 0.000783593842081713 GO:0023023 MHC protein complex binding 7/408 37/18639 0.189189189189189 8.64288553259142 1.3353591573012e-05 0.000931109521500016 GO:0005543 phospholipid binding 27/408 497/18639 0.0543259557344064 2.48181737483726 1.5046770099465e-05 0.000961739388857469 GO:0042056 chemoattractant activity 7/408 42/18639 0.166666666666667 7.61397058823529 3.18456395695157e-05 0.00176812165751186 GO:0001664 G protein-coupled receptor binding 19/408 297/18639 0.063973063973064 2.92253416518122 3.22734070471527e-05 0.00176812165751186 GO:0061134 peptidase regulator activity 16/408 226/18639 0.0707964601769911 3.23425299323269 4.05059534439854e-05 0.00207120441943579 GO:0002020 protease binding 12/408 136/18639 0.0882352941176471 4.03092560553633 4.53804870599283e-05 0.00217542709843531 GO:0042626 ATPase-coupled transmembrane transporter activity 10/408 98/18639 0.102040816326531 4.66161464585834 5.70408322683486e-05 0.00246964125828534 GO:0042288 MHC class I protein binding 5/408 20/18639 0.25 11.4209558823529 5.7957682723776e-05 0.00246964125828534 GO:0038187 pattern recognition receptor activity 7/408 48/18639 0.145833333333333 6.66222426470588 7.76364186520478e-05 0.00313405963716425 GO:0070008 serine-type exopeptidase activity 4/408 12/18639 0.333333333333333 15.2279411764706 9.74210616910778e-05 0.00373609771585283 GO:0003823 antigen binding 13/408 174/18639 0.0747126436781609 3.41315922920893 0.000123439585607282 0.00440934398968389 GO:0005126 cytokine receptor binding 17/408 275/18639 0.0618181818181818 2.82409090909091 0.000126474012741911 0.00440934398968389 GO:0050699 WW domain binding 5/408 24/18639 0.208333333333333 9.51746323529412 0.000147830220453126 0.0049298164820673 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/408 54/18639 0.12962962962963 5.92197712418301 0.000166843114860596 0.00533202787908655 GO:0120020 cholesterol transfer activity 5/408 25/18639 0.2 9.13676470588235 0.0001814888809 0.00556807886601201 GO:0005125 cytokine activity 15/408 234/18639 0.0641025641025641 2.92845022624434 0.00021109002722757 0.00622715580321332 GO:0042287 MHC protein binding 6/408 41/18639 0.146341463414634 6.68543758967001 0.000249252359151866 0.0070806133136845 GO:0023026 MHC class II protein complex binding 5/408 27/18639 0.185185185185185 8.45996732026144 0.000266018071769536 0.00728699503740123 GO:0008236 serine-type peptidase activity 13/408 194/18639 0.0670103092783505 3.06128714372347 0.000360076181035302 0.00952339416738194 GO:0017171 serine hydrolase activity 13/408 198/18639 0.0656565656565657 2.99944295900178 0.000437801857480401 0.0110083763735194 GO:0001968 fibronectin binding 5/408 30/18639 0.166666666666667 7.61397058823529 0.000444927858642896 0.0110083763735194 GO:0120015 sterol transfer activity 5/408 32/18639 0.15625 7.13809742647059 0.000606557617345879 0.014538427890759 GO:0097001 ceramide binding 4/408 19/18639 0.210526315789474 9.61764705882353 0.000675553391852285 0.0153874130119411 GO:0004197 cysteine-type endopeptidase activity 8/408 88/18639 0.0909090909090909 4.15307486631016 0.000687023627577572 0.0153874130119411 GO:0140311 protein sequestering activity 5/408 33/18639 0.151515151515152 6.92179144385027 0.000702163566385839 0.0153874130119411 GO:0048020 CCR chemokine receptor binding 6/408 50/18639 0.12 5.48205882352941 0.000746512858330413 0.0159048711760952 GO:0140313 molecular sequestering activity 6/408 55/18639 0.109090909090909 4.98368983957219 0.00124257114156701 0.0257581639346459 GO:0016504 peptidase activator activity 6/408 57/18639 0.105263157894737 4.80882352941176 0.00149948275438985 0.0296426899023886 GO:0008199 ferric iron binding 3/408 11/18639 0.272727272727273 12.4592245989305 0.00150725541876552 0.0296426899023886 GO:0004175 endopeptidase activity 19/408 405/18639 0.0469135802469136 2.1431917211329 0.00159992607115068 0.0306785824143144 GO:0061791 GTPase motor activity 5/408 40/18639 0.125 5.71047794117647 0.00171750758064647 0.0313649598656153 GO:1990606 membrane scission GTPase motor activity 5/408 40/18639 0.125 5.71047794117647 0.00171750758064647 0.0313649598656153 GO:0008238 exopeptidase activity 8/408 102/18639 0.0784313725490196 3.58304498269896 0.00179961535752658 0.0321001157958811 GO:0001530 lipopolysaccharide binding 5/408 41/18639 0.121951219512195 5.57119799139168 0.00192143191696517 0.0334940518252792 GO:0004859 phospholipase inhibitor activity 3/408 12/18639 0.25 11.4209558823529 0.00197720020445701 0.0337002790404116 GO:0004857 enzyme inhibitor activity 19/408 416/18639 0.0456730769230769 2.08652078619909 0.00216528257624191 0.0361037333908162 GO:0008198 ferrous iron binding 4/408 26/18639 0.153846153846154 7.02828054298643 0.00230898150345511 0.037295911625838 GO:0140375 immune receptor activity 10/408 156/18639 0.0641025641025641 2.92845022624434 0.00233403358284253 0.037295911625838 GO:0061135 endopeptidase regulator activity 11/408 184/18639 0.0597826086956522 2.73109814578005 0.00249417296336754 0.0390414421000592 GO:0140297 DNA-binding transcription factor binding 21/408 488/18639 0.0430327868852459 1.96590224204436 0.00264957228458512 0.0406444388455357 GO:0004866 endopeptidase inhibitor activity 10/408 161/18639 0.062111801242236 2.83750456704421 0.00293491687849254 0.0434982593411069 GO:0038024 cargo receptor activity 6/408 65/18639 0.0923076923076923 4.21696832579186 0.00294903453160047 0.0434982593411069 GO:0046625 sphingolipid binding 4/408 28/18639 0.142857142857143 6.52626050420168 0.00305531344755083 0.0441606874184656 GO:0005545 1-phosphatidylinositol binding 3/408 14/18639 0.214285714285714 9.78939075630252 0.00316667250067224 0.0441606874184656 GO:0044548 S100 protein binding 3/408 14/18639 0.214285714285714 9.78939075630252 0.00316667250067224 0.0441606874184656 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/408 29/18639 0.137931034482759 6.30121703853955 0.00348376446387663 0.0477151311391674 GO:0015399 primary active transmembrane transporter activity 10/408 166/18639 0.0602409638554217 2.75203756201276 0.00365334288285784 0.0491598945816134 GO:0015929 hexosaminidase activity 3/408 15/18639 0.2 9.13676470588235 0.00389459202211024 0.0515026220854924 GO:0030414 peptidase inhibitor activity 10/408 169/18639 0.0591715976331361 2.70318482422555 0.00414717355770964 0.0539132562502254 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 16/408 349/18639 0.0458452722063037 2.09438732513063 0.00453562936478295 0.0579804620464753 GO:0055102 lipase inhibitor activity 3/408 16/18639 0.1875 8.56571691176471 0.00471623442899708 0.0593008492957501 GO:0005518 collagen binding 6/408 72/18639 0.0833333333333333 3.80698529411765 0.00491074279446997 0.0607506406993301 GO:0004252 serine-type endopeptidase activity 10/408 176/18639 0.0568181818181818 2.59567179144385 0.00550504752288823 0.066491031448854 GO:0008429 phosphatidylethanolamine binding 3/408 17/18639 0.176470588235294 8.06185121107266 0.0056348331736317 0.066491031448854 GO:0045236 CXCR chemokine receptor binding 3/408 17/18639 0.176470588235294 8.06185121107266 0.0056348331736317 0.066491031448854 GO:0031690 adrenergic receptor binding 3/408 18/18639 0.166666666666667 7.61397058823529 0.00665326988514551 0.0773190606349485 GO:0016298 lipase activity 8/408 130/18639 0.0615384615384615 2.81131221719457 0.00788298640502093 0.0902425458604635 GO:0048306 calcium-dependent protein binding 6/408 80/18639 0.075 3.42628676470588 0.00816902331568415 0.0921417776930844 GO:0008234 cysteine-type peptidase activity 10/408 187/18639 0.053475935828877 2.44298521547656 0.00831434405691439 0.0924217665457006 GO:0016004 phospholipase activator activity 3/408 20/18639 0.15 6.85257352941176 0.0089995280938445 0.0986091149711247 GO:0005178 integrin binding 9/408 161/18639 0.0559006211180124 2.55375411033979 0.00913141756283014 0.0986450319815594 GO:0008135 translation factor activity, RNA binding 6/408 83/18639 0.072289156626506 3.30244507441531 0.00971866862159163 0.103530817121678 GO:0180051 translation factor activity 6/408 84/18639 0.0714285714285714 3.26313025210084 0.0102787642208179 0.107997426813251 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 19/408 484/18639 0.0392561983471074 1.79337323772484 0.0106388479639777 0.110270221464471 GO:0004177 aminopeptidase activity 4/408 40/18639 0.1 4.56838235294118 0.0111055984994371 0.113573253987577 GO:0016209 antioxidant activity 6/408 86/18639 0.0697674418604651 3.18724350205198 0.011467050597435 0.115726681687272 GO:0001216 DNA-binding transcription activator activity 19/408 491/18639 0.0386965376782077 1.76780579849048 0.0122386940117433 0.121910107883209 GO:0120013 lipid transfer activity 5/408 65/18639 0.0769230769230769 3.51414027149321 0.013839871650214 0.136092071227104 GO:0060229 lipase activator activity 3/408 24/18639 0.125 5.71047794117647 0.0149817663247874 0.143474985900907 GO:0070300 phosphatidic acid binding 3/408 24/18639 0.125 5.71047794117647 0.0149817663247874 0.143474985900907 GO:0022853 active monoatomic ion transmembrane transporter activity 7/408 118/18639 0.0593220338983051 2.71005732801595 0.0151518563989223 0.143474985900907 GO:0030547 signaling receptor inhibitor activity 4/408 44/18639 0.0909090909090909 4.15307486631016 0.015411689834649 0.144155684185071 GO:0045296 cadherin binding 14/408 334/18639 0.0419161676646707 1.91489080662205 0.0158269733353389 0.146256488532589 GO:0019209 kinase activator activity 8/408 148/18639 0.0540540540540541 2.46939586645469 0.016349534156918 0.149286817837573 GO:1990841 promoter-specific chromatin binding 5/408 68/18639 0.0735294117647059 3.35910467128028 0.0165689400969764 0.149510318286834 GO:0004867 serine-type endopeptidase inhibitor activity 6/408 95/18639 0.0631578947368421 2.88529411764706 0.018025054245976 0.158835262103481 GO:1901681 sulfur compound binding 12/408 275/18639 0.0436363636363636 1.99347593582888 0.0184884380224549 0.158835262103481 GO:0005112 Notch binding 3/408 26/18639 0.115384615384615 5.27121040723982 0.0186377752142285 0.158835262103481 GO:0019865 immunoglobulin binding 3/408 26/18639 0.115384615384615 5.27121040723982 0.0186377752142285 0.158835262103481 GO:0070412 R-SMAD binding 3/408 26/18639 0.115384615384615 5.27121040723982 0.0186377752142285 0.158835262103481 GO:0005031 tumor necrosis factor receptor activity 2/408 10/18639 0.2 9.13676470588235 0.0191488101009752 0.159642797254869 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/408 10/18639 0.2 9.13676470588235 0.0191488101009752 0.159642797254869 GO:0033218 amide binding 11/408 247/18639 0.0445344129554656 2.03450226244344 0.0205947217291022 0.166596131491819 GO:0005044 scavenger receptor activity 3/408 27/18639 0.111111111111111 5.07598039215686 0.0206344621795603 0.166596131491819 GO:0035255 ionotropic glutamate receptor binding 3/408 27/18639 0.111111111111111 5.07598039215686 0.0206344621795603 0.166596131491819 GO:0001851 complement component C3b binding 2/408 11/18639 0.181818181818182 8.30614973262032 0.0230691555859107 0.175304398730881 GO:0008432 JUN kinase binding 2/408 11/18639 0.181818181818182 8.30614973262032 0.0230691555859107 0.175304398730881 GO:0019864 IgG binding 2/408 11/18639 0.181818181818182 8.30614973262032 0.0230691555859107 0.175304398730881 GO:0042608 T cell receptor binding 2/408 11/18639 0.181818181818182 8.30614973262032 0.0230691555859107 0.175304398730881 GO:0050786 RAGE receptor binding 2/408 11/18639 0.181818181818182 8.30614973262032 0.0230691555859107 0.175304398730881 GO:0035091 phosphatidylinositol binding 12/408 284/18639 0.0422535211267606 1.9303024026512 0.0230844123491774 0.175304398730881 GO:0003725 double-stranded RNA binding 5/408 75/18639 0.0666666666666667 3.04558823529412 0.0242668406521562 0.182477125296116 GO:0043236 laminin binding 3/408 29/18639 0.103448275862069 4.72591277890467 0.0249662902847313 0.184126390849893 GO:0051861 glycolipid binding 3/408 29/18639 0.103448275862069 4.72591277890467 0.0249662902847313 0.184126390849893 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/408 30/18639 0.1 4.56838235294118 0.0273012916732838 0.199429435365797 GO:0046332 SMAD binding 5/408 79/18639 0.0632911392405063 2.89138123603872 0.0295505869712066 0.213823586857693 GO:0003925 G protein activity 4/408 54/18639 0.0740740740740741 3.38398692810457 0.0303205256307724 0.215202772550082 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/408 54/18639 0.0740740740740741 3.38398692810457 0.0303205256307724 0.215202772550082 GO:0019001 guanyl nucleotide binding 15/408 400/18639 0.0375 1.71314338235294 0.0309260182323962 0.215202772550082 GO:0032561 guanyl ribonucleotide binding 15/408 400/18639 0.0375 1.71314338235294 0.0309260182323962 0.215202772550082 GO:0003924 GTPase activity 13/408 331/18639 0.0392749244712991 1.7942287186778 0.0311440779049011 0.215202772550082 GO:0005035 death receptor activity 2/408 13/18639 0.153846153846154 7.02828054298643 0.0317891237746682 0.215479062789292 GO:0051059 NF-kappaB binding 3/408 32/18639 0.09375 4.28285845588235 0.0323078125433749 0.215479062789292 GO:0071813 lipoprotein particle binding 3/408 32/18639 0.09375 4.28285845588235 0.0323078125433749 0.215479062789292 GO:0071814 protein-lipid complex binding 3/408 32/18639 0.09375 4.28285845588235 0.0323078125433749 0.215479062789292 GO:0004620 phospholipase activity 6/408 109/18639 0.055045871559633 2.51470588235294 0.0326862427179062 0.216123691074432 GO:0030295 protein kinase activator activity 7/408 139/18639 0.0503597122302158 2.30062420651714 0.0334286529846189 0.219143391788057 GO:0001540 amyloid-beta binding 5/408 83/18639 0.0602409638554217 2.75203756201276 0.0355080828628875 0.230802538608769 GO:0008201 heparin binding 8/408 172/18639 0.0465116279069767 2.12482900136799 0.0358826309786029 0.23127712571923 GO:0019763 immunoglobulin receptor activity 2/408 14/18639 0.142857142857143 6.52626050420168 0.0365595323203343 0.23174513462559 GO:0019992 diacylglycerol binding 2/408 14/18639 0.142857142857143 6.52626050420168 0.0365595323203343 0.23174513462559 GO:0005525 GTP binding 14/408 378/18639 0.037037037037037 1.69199346405229 0.0395644694917076 0.248737279509342 GO:0001786 phosphatidylserine binding 4/408 59/18639 0.0677966101694915 3.09720837487537 0.04012135081742 0.249184564413178 GO:0004623 phospholipase A2 activity 3/408 35/18639 0.0857142857142857 3.91575630252101 0.040649238013506 0.249184564413178 GO:0005539 glycosaminoglycan binding 10/408 242/18639 0.0413223140495868 1.88776130286825 0.0410173906411242 0.249184564413178 GO:0031386 protein tag activity 2/408 15/18639 0.133333333333333 6.09117647058823 0.0415849077508302 0.249184564413178 GO:0120283 protein serine/threonine kinase binding 2/408 15/18639 0.133333333333333 6.09117647058823 0.0415849077508302 0.249184564413178 GO:0141047 molecular tag activity 2/408 15/18639 0.133333333333333 6.09117647058823 0.0415849077508302 0.249184564413178 GO:0005319 lipid transporter activity 8/408 178/18639 0.0449438202247191 2.05320555188367 0.0425204653636428 0.252815480107861 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 5/408 91/18639 0.0549450549450549 2.51010019392372 0.0495072645019398 0.28986314406861 GO:0072341 modified amino acid binding 5/408 91/18639 0.0549450549450549 2.51010019392372 0.0495072645019398 0.28986314406861 GO:0043531 ADP binding 3/408 38/18639 0.0789473684210526 3.60661764705882 0.0499658756957644 0.290332020141298 GO:1901981 phosphatidylinositol phosphate binding 8/408 185/18639 0.0432432432432432 1.97551669316375 0.051234844848148 0.293069383244105 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/408 17/18639 0.117647058823529 5.37456747404844 0.0523474648037059 0.293069383244105 GO:0008484 sulfuric ester hydrolase activity 2/408 17/18639 0.117647058823529 5.37456747404844 0.0523474648037059 0.293069383244105 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/408 17/18639 0.117647058823529 5.37456747404844 0.0523474648037059 0.293069383244105 GO:0030169 low-density lipoprotein particle binding 2/408 17/18639 0.117647058823529 5.37456747404844 0.0523474648037059 0.293069383244105 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/408 40/18639 0.075 3.42628676470588 0.0567022122511609 0.309246086404579 GO:0050997 quaternary ammonium group binding 3/408 40/18639 0.075 3.42628676470588 0.0567022122511609 0.309246086404579 GO:0003746 translation elongation factor activity 2/408 18/18639 0.111111111111111 5.07598039215686 0.058059239168526 0.309246086404579 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/408 18/18639 0.111111111111111 5.07598039215686 0.058059239168526 0.309246086404579 GO:0004706 JUN kinase kinase kinase activity 2/408 18/18639 0.111111111111111 5.07598039215686 0.058059239168526 0.309246086404579 GO:0008525 phosphatidylcholine transporter activity 2/408 18/18639 0.111111111111111 5.07598039215686 0.058059239168526 0.309246086404579 GO:0032393 MHC class I receptor activity 2/408 18/18639 0.111111111111111 5.07598039215686 0.058059239168526 0.309246086404579 GO:0050840 extracellular matrix binding 4/408 67/18639 0.0597014925373134 2.72739244951712 0.0591221468245951 0.312735769754927 GO:0032934 sterol binding 4/408 68/18639 0.0588235294117647 2.68728373702422 0.0617817222450712 0.324565623027189 GO:0048487 beta-tubulin binding 3/408 42/18639 0.0714285714285714 3.26313025210084 0.0638448733180872 0.327126210075581 GO:0043395 heparan sulfate proteoglycan binding 2/408 19/18639 0.105263157894737 4.80882352941176 0.0639751388674539 0.327126210075581 GO:0050145 nucleoside monophosphate kinase activity 2/408 19/18639 0.105263157894737 4.80882352941176 0.0639751388674539 0.327126210075581 GO:0140036 ubiquitin-modified protein reader activity 2/408 19/18639 0.105263157894737 4.80882352941176 0.0639751388674539 0.327126210075581 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/408 130/18639 0.0461538461538462 2.10848416289593 0.0663298873943328 0.336920686301015 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/408 20/18639 0.1 4.56838235294118 0.0700835400645217 0.351333825029334 GO:0016505 peptidase activator activity involved in apoptotic process 2/408 20/18639 0.1 4.56838235294118 0.0700835400645217 0.351333825029334 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/408 268/18639 0.0373134328358209 1.7046202809482 0.0713627043702422 0.355423339298544 GO:0001846 opsonin binding 2/408 21/18639 0.0952380952380952 4.35084033613445 0.0763732277916705 0.377924294943298 GO:0044325 transmembrane transporter binding 6/408 136/18639 0.0441176470588235 2.01546280276817 0.0786533435204354 0.386712272308807 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/408 46/18639 0.0652173913043478 2.97937979539642 0.0792946536061775 0.387382161248014 GO:0016922 nuclear receptor binding 6/408 137/18639 0.0437956204379562 2.00075139544869 0.0808244961054685 0.387632094034714 GO:0019003 GDP binding 4/408 75/18639 0.0533333333333333 2.43647058823529 0.0821154767122958 0.387632094034714 GO:0008970 phospholipase A1 activity 2/408 22/18639 0.0909090909090909 4.15307486631016 0.0828333836908635 0.387632094034714 GO:0034062 5'-3' RNA polymerase activity 2/408 22/18639 0.0909090909090909 4.15307486631016 0.0828333836908635 0.387632094034714 GO:0097747 RNA polymerase activity 2/408 22/18639 0.0909090909090909 4.15307486631016 0.0828333836908635 0.387632094034714 GO:0140035 ubiquitin-like protein reader activity 2/408 22/18639 0.0909090909090909 4.15307486631016 0.0828333836908635 0.387632094034714 GO:0005504 fatty acid binding 3/408 47/18639 0.0638297872340425 2.9159887359199 0.0833889120152905 0.387632094034714 GO:0140359 ABC-type transporter activity 3/408 47/18639 0.0638297872340425 2.9159887359199 0.0833889120152905 0.387632094034714 GO:0001217 DNA-binding transcription repressor activity 10/408 278/18639 0.0359712230215827 1.6433030046551 0.0860373549555998 0.397534043680392 GO:0005496 steroid binding 5/408 108/18639 0.0462962962962963 2.11499183006536 0.0886078429049319 0.405981605507317 GO:0030246 carbohydrate binding 10/408 280/18639 0.0357142857142857 1.63156512605042 0.089176950747141 0.405981605507317 GO:0005212 structural constituent of eye lens 2/408 23/18639 0.0869565217391304 3.97250639386189 0.0894535740948325 0.405981605507317 GO:0035254 glutamate receptor binding 3/408 49/18639 0.0612244897959184 2.79696878751501 0.0918418436390017 0.414368788653614 GO:0043021 ribonucleoprotein complex binding 7/408 177/18639 0.0395480225988701 1.80670488534397 0.094714144611851 0.420106613110651 GO:0033293 monocarboxylic acid binding 4/408 79/18639 0.0506329113924051 2.31310498883098 0.095036036054787 0.420106613110651 GO:0032813 tumor necrosis factor receptor superfamily binding 3/408 50/18639 0.06 2.74102941176471 0.096196416175449 0.420106613110651 GO:0019957 C-C chemokine binding 2/408 24/18639 0.0833333333333333 3.80698529411765 0.0962237384375638 0.420106613110651 GO:0030552 cAMP binding 2/408 24/18639 0.0833333333333333 3.80698529411765 0.0962237384375638 0.420106613110651 GO:1902936 phosphatidylinositol bisphosphate binding 5/408 111/18639 0.045045045045045 2.05782988871224 0.0967983064372586 0.420106613110651 GO:0019955 cytokine binding 6/408 144/18639 0.0416666666666667 1.90349264705882 0.0969476799486118 0.420106613110651 GO:0003743 translation initiation factor activity 3/408 51/18639 0.0588235294117647 2.68728373702422 0.100633602762205 0.431501503605352 GO:0019207 kinase regulator activity 10/408 287/18639 0.0348432055749129 1.59177085468334 0.100702436956138 0.431501503605352 GO:0001618 virus receptor activity 4/408 81/18639 0.0493827160493827 2.25599128540305 0.101834301958518 0.433927275567687 GO:0001848 complement binding 2/408 25/18639 0.08 3.65470588235294 0.103134177985855 0.434636892940389 GO:0004709 MAP kinase kinase kinase activity 2/408 25/18639 0.08 3.65470588235294 0.103134177985855 0.434636892940389 GO:0140272 exogenous protein binding 4/408 82/18639 0.0487804878048781 2.22847919655667 0.105315317254251 0.441403542808802 GO:0030165 PDZ domain binding 4/408 83/18639 0.0481927710843374 2.20163004961021 0.108849860767738 0.449492781519347 GO:0019887 protein kinase regulator activity 9/408 255/18639 0.0352941176470588 1.61237024221453 0.108883827301451 0.449492781519347 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/408 53/18639 0.0566037735849057 2.58587680355161 0.109747277968606 0.449492781519347 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/408 26/18639 0.0769230769230769 3.51414027149321 0.11017554488349 0.449492781519347 GO:0070006 metalloaminopeptidase activity 2/408 26/18639 0.0769230769230769 3.51414027149321 0.11017554488349 0.449492781519347 GO:0015078 proton transmembrane transporter activity 7/408 185/18639 0.0378378378378378 1.72857710651828 0.112542803351643 0.456721323654551 GO:0015485 cholesterol binding 3/408 54/18639 0.0555555555555556 2.53799019607843 0.114419439870832 0.461893212531201 GO:0001671 ATPase activator activity 2/408 27/18639 0.0740740740740741 3.38398692810457 0.117338831499805 0.466315459898188 GO:0004364 glutathione transferase activity 2/408 27/18639 0.0740740740740741 3.38398692810457 0.117338831499805 0.466315459898188 GO:0008266 poly(U) RNA binding 2/408 27/18639 0.0740740740740741 3.38398692810457 0.117338831499805 0.466315459898188 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/408 86/18639 0.0465116279069767 2.12482900136799 0.119766334261682 0.473509166900569 GO:0008081 phosphoric diester hydrolase activity 4/408 87/18639 0.0459770114942529 2.10040567951318 0.123506565797561 0.480301412950865 GO:0019789 SUMO transferase activity 2/408 28/18639 0.0714285714285714 3.26313025210084 0.124615360074605 0.480301412950865 GO:0051019 mitogen-activated protein kinase binding 2/408 28/18639 0.0714285714285714 3.26313025210084 0.124615360074605 0.480301412950865 GO:0051959 dynein light intermediate chain binding 2/408 28/18639 0.0714285714285714 3.26313025210084 0.124615360074605 0.480301412950865 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/408 28/18639 0.0714285714285714 3.26313025210084 0.124615360074605 0.480301412950865 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/408 57/18639 0.0526315789473684 2.40441176470588 0.128870907207392 0.49421992914035 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/408 29/18639 0.0689655172413793 3.15060851926978 0.131996772651633 0.501195666454467 GO:0097472 cyclin-dependent protein kinase activity 2/408 29/18639 0.0689655172413793 3.15060851926978 0.131996772651633 0.501195666454467 GO:0004879 nuclear receptor activity 3/408 59/18639 0.0508474576271186 2.32290628115653 0.138845554044782 0.514314141017729 GO:0070888 E-box binding 3/408 59/18639 0.0508474576271186 2.32290628115653 0.138845554044782 0.514314141017729 GO:0008187 poly-pyrimidine tract binding 2/408 30/18639 0.0666666666666667 3.04558823529412 0.139475021292943 0.514314141017729 GO:0016769 transferase activity, transferring nitrogenous groups 2/408 30/18639 0.0666666666666667 3.04558823529412 0.139475021292943 0.514314141017729 GO:0031210 phosphatidylcholine binding 2/408 30/18639 0.0666666666666667 3.04558823529412 0.139475021292943 0.514314141017729 GO:0048019 receptor antagonist activity 2/408 30/18639 0.0666666666666667 3.04558823529412 0.139475021292943 0.514314141017729 GO:0005096 GTPase activator activity 9/408 271/18639 0.033210332103321 1.51717495116128 0.141962662957731 0.520982595639139 GO:0098531 ligand-modulated transcription factor activity 3/408 60/18639 0.05 2.28419117647059 0.143928304012652 0.525680996084304 GO:0008083 growth factor activity 6/408 162/18639 0.037037037037037 1.69199346405229 0.145488827209545 0.528862229714317 GO:0005164 tumor necrosis factor receptor binding 2/408 31/18639 0.0645161290322581 2.94734345351044 0.147042358566775 0.529490558782707 GO:0047499 calcium-independent phospholipase A2 activity 2/408 31/18639 0.0645161290322581 2.94734345351044 0.147042358566775 0.529490558782707 GO:0047498 calcium-dependent phospholipase A2 activity 2/408 32/18639 0.0625 2.85523897058824 0.154691328301669 0.554431069193364 GO:0031072 heat shock protein binding 5/408 131/18639 0.0381679389312977 1.74365738661877 0.160313439843878 0.566236901418334 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/408 33/18639 0.0606060606060606 2.76871657754011 0.162414756599783 0.566236901418334 GO:0019956 chemokine binding 2/408 33/18639 0.0606060606060606 2.76871657754011 0.162414756599783 0.566236901418334 GO:0030296 protein tyrosine kinase activator activity 2/408 33/18639 0.0606060606060606 2.76871657754011 0.162414756599783 0.566236901418334 GO:0071889 14-3-3 protein binding 2/408 33/18639 0.0606060606060606 2.76871657754011 0.162414756599783 0.566236901418334 GO:0140416 transcription regulator inhibitor activity 2/408 33/18639 0.0606060606060606 2.76871657754011 0.162414756599783 0.566236901418334 GO:0008235 metalloexopeptidase activity 3/408 66/18639 0.0454545454545455 2.07653743315508 0.175620861450773 0.592468104387078 GO:0043130 ubiquitin binding 4/408 100/18639 0.04 1.82735294117647 0.176262670254827 0.592468104387078 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/408 36/18639 0.0555555555555556 2.53799019607843 0.185964106290618 0.592468104387078 GO:0005484 SNAP receptor activity 2/408 36/18639 0.0555555555555556 2.53799019607843 0.185964106290618 0.592468104387078 GO:0005548 phospholipid transporter activity 3/408 68/18639 0.0441176470588235 2.01546280276817 0.186587893304435 0.592468104387078 GO:0046982 protein heterodimerization activity 11/408 369/18639 0.029810298102981 1.36184839789574 0.187708620110441 0.592468104387078 GO:0002039 p53 binding 3/408 69/18639 0.0434782608695652 1.98625319693095 0.192137183016803 0.592468104387078 GO:0019213 deacetylase activity 2/408 37/18639 0.0540540540540541 2.46939586645469 0.193918974745595 0.592468104387078 GO:0030551 cyclic nucleotide binding 2/408 37/18639 0.0540540540540541 2.46939586645469 0.193918974745595 0.592468104387078 GO:0003796 lysozyme activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0004090 carbonyl reductase (NADPH) activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0004382 GDP phosphatase activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0004955 prostaglandin receptor activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0005337 nucleoside transmembrane transporter activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0005345 purine nucleobase transmembrane transporter activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0005522 profilin binding 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0008239 dipeptidyl-peptidase activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0031419 cobalamin binding 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0032395 MHC class II receptor activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0042975 peroxisome proliferator activated receptor binding 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0043208 glycosphingolipid binding 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0043422 protein kinase B binding 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0051880 G-quadruplex DNA binding 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0070513 death domain binding 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0141109 transporter activator activity 1/408 10/18639 0.1 4.56838235294118 0.198588898648551 0.592468104387078 GO:0000149 SNARE binding 4/408 106/18639 0.0377358490566038 1.72391786903441 0.20282221156861 0.592468104387078 GO:0022804 active transmembrane transporter activity 13/408 457/18639 0.0284463894967177 1.29953983781696 0.20426974480136 0.592468104387078 GO:0019888 protein phosphatase regulator activity 4/408 107/18639 0.0373831775700935 1.70780648708081 0.207360498417603 0.592468104387078 GO:0019903 protein phosphatase binding 5/408 144/18639 0.0347222222222222 1.58624387254902 0.208643056137208 0.592468104387078 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/408 39/18639 0.0512820512820513 2.34276018099548 0.209950634159818 0.592468104387078 GO:0043539 protein serine/threonine kinase activator activity 3/408 73/18639 0.0410958904109589 1.87741740531829 0.214723518171868 0.592468104387078 GO:0003953 NAD+ nucleosidase activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0004954 prostanoid receptor activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0008503 benzodiazepine receptor activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0008526 phosphatidylinositol transfer activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0010854 adenylate cyclase regulator activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0015173 aromatic amino acid transmembrane transporter activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0015205 nucleobase transmembrane transporter activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0019215 intermediate filament binding 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0034056 estrogen response element binding 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0070990 snRNP binding 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0097493 structural molecule activity conferring elasticity 1/408 11/18639 0.0909090909090909 4.15307486631016 0.216140872954814 0.592468104387078 GO:0008237 metallopeptidase activity 6/408 184/18639 0.0326086956521739 1.48968989769821 0.216718519689483 0.592468104387078 GO:0015036 disulfide oxidoreductase activity 2/408 40/18639 0.05 2.28419117647059 0.218016340576063 0.592468104387078 GO:0030331 nuclear estrogen receptor binding 2/408 40/18639 0.05 2.28419117647059 0.218016340576063 0.592468104387078 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/408 40/18639 0.05 2.28419117647059 0.218016340576063 0.592468104387078 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/408 41/18639 0.0487804878048781 2.22847919655667 0.226108278070952 0.592468104387078 GO:0031406 carboxylic acid binding 6/408 187/18639 0.0320855614973262 1.46579112928594 0.227250311703388 0.592468104387078 GO:0043022 ribosome binding 4/408 112/18639 0.0357142857142857 1.63156512605042 0.230467881100696 0.592468104387078 GO:0017022 myosin binding 3/408 76/18639 0.0394736842105263 1.80330882352941 0.232014225338939 0.592468104387078 GO:0019842 vitamin binding 5/408 150/18639 0.0333333333333333 1.52279411764706 0.23239240036809 0.592468104387078 GO:0004000 adenosine deaminase activity 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0004875 complement receptor activity 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0005095 GTPase inhibitor activity 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0008603 cAMP-dependent protein kinase regulator activity 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0010853 cyclase activator activity 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0015269 calcium-activated potassium channel activity 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0016801 hydrolase activity, acting on ether bonds 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0016803 ether hydrolase activity 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0035259 nuclear glucocorticoid receptor binding 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0035497 cAMP response element binding 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0070410 co-SMAD binding 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0097677 STAT family protein binding 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/408 12/18639 0.0833333333333333 3.80698529411765 0.233309357163234 0.592468104387078 GO:0035198 miRNA binding 2/408 42/18639 0.0476190476190476 2.17542016806723 0.234221448308595 0.592468104387078 GO:0043177 organic acid binding 6/408 189/18639 0.0317460317460317 1.45028011204482 0.234361999633486 0.592468104387078 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/408 43/18639 0.0465116279069767 2.12482900136799 0.242351058187063 0.592468104387078 GO:0008200 ion channel inhibitor activity 2/408 43/18639 0.0465116279069767 2.12482900136799 0.242351058187063 0.592468104387078 GO:0008375 acetylglucosaminyltransferase activity 2/408 43/18639 0.0465116279069767 2.12482900136799 0.242351058187063 0.592468104387078 GO:0048156 tau protein binding 2/408 43/18639 0.0465116279069767 2.12482900136799 0.242351058187063 0.592468104387078 GO:0003774 cytoskeletal motor activity 5/408 153/18639 0.0326797385620915 1.4929354094579 0.244546675272029 0.592468104387078 GO:0017124 SH3 domain binding 4/408 115/18639 0.0347826086956522 1.58900255754476 0.244627606265369 0.592468104387078 GO:0005506 iron ion binding 5/408 154/18639 0.0324675324675325 1.4832410236822 0.248635262718672 0.592468104387078 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0005542 folic acid binding 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0008035 high-density lipoprotein particle binding 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0032396 inhibitory MHC class I receptor activity 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0035325 Toll-like receptor binding 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0046974 histone H3K9 methyltransferase activity 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0046975 histone H3K36 methyltransferase activity 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0071837 HMG box domain binding 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0089720 caspase binding 1/408 13/18639 0.0769230769230769 3.51414027149321 0.250102709945614 0.592468104387078 GO:0016248 channel inhibitor activity 2/408 44/18639 0.0454545454545455 2.07653743315508 0.250492513285755 0.592468104387078 GO:0019205 nucleobase-containing compound kinase activity 2/408 44/18639 0.0454545454545455 2.07653743315508 0.250492513285755 0.592468104387078 GO:0043014 alpha-tubulin binding 2/408 44/18639 0.0454545454545455 2.07653743315508 0.250492513285755 0.592468104387078 GO:0019208 phosphatase regulator activity 4/408 117/18639 0.0341880341880342 1.56184012066365 0.254173274328885 0.592468104387078 GO:1990782 protein tyrosine kinase binding 4/408 117/18639 0.0341880341880342 1.56184012066365 0.254173274328885 0.592468104387078 GO:0051020 GTPase binding 9/408 315/18639 0.0285714285714286 1.30525210084034 0.254521797097482 0.592468104387078 GO:0140303 intramembrane lipid transporter activity 2/408 45/18639 0.0444444444444444 2.03039215686274 0.258641411500159 0.592468104387078 GO:0141110 transporter inhibitor activity 2/408 45/18639 0.0444444444444444 2.03039215686274 0.258641411500159 0.592468104387078 GO:0030971 receptor tyrosine kinase binding 3/408 81/18639 0.037037037037037 1.69199346405229 0.26134215839855 0.592468104387078 GO:0033192 calmodulin-dependent protein phosphatase activity 3/408 81/18639 0.037037037037037 1.69199346405229 0.26134215839855 0.592468104387078 GO:0140791 histone H2AXS140 phosphatase activity 3/408 81/18639 0.037037037037037 1.69199346405229 0.26134215839855 0.592468104387078 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/408 81/18639 0.037037037037037 1.69199346405229 0.26134215839855 0.592468104387078 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/408 81/18639 0.037037037037037 1.69199346405229 0.26134215839855 0.592468104387078 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/408 81/18639 0.037037037037037 1.69199346405229 0.26134215839855 0.592468104387078 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/408 81/18639 0.037037037037037 1.69199346405229 0.26134215839855 0.592468104387078 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/408 81/18639 0.037037037037037 1.69199346405229 0.26134215839855 0.592468104387078 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/408 81/18639 0.037037037037037 1.69199346405229 0.26134215839855 0.592468104387078 GO:0004065 arylsulfatase activity 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0005347 ATP transmembrane transporter activity 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0008191 metalloendopeptidase inhibitor activity 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0008494 translation activator activity 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0015926 glucosidase activity 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0016530 metallochaperone activity 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0042043 neurexin family protein binding 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0043176 amine binding 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0061665 SUMO ligase activity 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0061783 peptidoglycan muralytic activity 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0071933 Arp2/3 complex binding 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/408 14/18639 0.0714285714285714 3.26313025210084 0.266529108224482 0.592468104387078 GO:0004180 carboxypeptidase activity 2/408 46/18639 0.0434782608695652 1.98625319693095 0.266793536858976 0.592468104387078 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/408 82/18639 0.0365853658536585 1.6713593974175 0.267267228315422 0.592468104387078 GO:0033549 MAP kinase phosphatase activity 3/408 82/18639 0.0365853658536585 1.6713593974175 0.267267228315422 0.592468104387078 GO:0032182 ubiquitin-like protein binding 4/408 120/18639 0.0333333333333333 1.52279411764706 0.268630242930508 0.593773476448702 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/408 83/18639 0.036144578313253 1.65122253720765 0.273207879598461 0.600263469745365 GO:0051082 unfolded protein binding 4/408 121/18639 0.0330578512396694 1.5102090422946 0.273482150488988 0.600263469745365 GO:0042578 phosphoric ester hydrolase activity 10/408 363/18639 0.0275482093663912 1.2585075352455 0.273914230001145 0.600263469745365 GO:0017018 myosin phosphatase activity 3/408 84/18639 0.0357142857142857 1.63156512605042 0.27916235254481 0.60147141398051 GO:0051117 ATPase binding 3/408 84/18639 0.0357142857142857 1.63156512605042 0.27916235254481 0.60147141398051 GO:0004953 icosanoid receptor activity 1/408 15/18639 0.0666666666666667 3.04558823529412 0.282596551115457 0.60147141398051 GO:0005041 low-density lipoprotein particle receptor activity 1/408 15/18639 0.0666666666666667 3.04558823529412 0.282596551115457 0.60147141398051 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/408 15/18639 0.0666666666666667 3.04558823529412 0.282596551115457 0.60147141398051 GO:0005523 tropomyosin binding 1/408 15/18639 0.0666666666666667 3.04558823529412 0.282596551115457 0.60147141398051 GO:0030553 cGMP binding 1/408 15/18639 0.0666666666666667 3.04558823529412 0.282596551115457 0.60147141398051 GO:0050700 CARD domain binding 1/408 15/18639 0.0666666666666667 3.04558823529412 0.282596551115457 0.60147141398051 GO:0050780 dopamine receptor binding 1/408 15/18639 0.0666666666666667 3.04558823529412 0.282596551115457 0.60147141398051 GO:0032266 phosphatidylinositol-3-phosphate binding 2/408 48/18639 0.0416666666666667 1.90349264705882 0.283091499930853 0.60147141398051 GO:0140693 molecular condensate scaffold activity 2/408 48/18639 0.0416666666666667 1.90349264705882 0.283091499930853 0.60147141398051 GO:0060590 ATPase regulator activity 2/408 49/18639 0.0408163265306122 1.86464585834334 0.291229783177314 0.610484739297743 GO:0004708 MAP kinase kinase activity 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0005159 insulin-like growth factor receptor binding 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0005521 lamin binding 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0008142 oxysterol binding 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0016722 oxidoreductase activity, acting on metal ions 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0022858 alanine transmembrane transporter activity 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0030275 LRR domain binding 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0140328 floppase activity 1/408 16/18639 0.0625 2.85523897058824 0.29831286378432 0.610484739297743 GO:0030544 Hsp70 protein binding 2/408 51/18639 0.0392156862745098 1.79152249134948 0.307467298804033 0.610484739297743 GO:0003727 single-stranded RNA binding 3/408 89/18639 0.0337078651685393 1.53990416391276 0.309082628936077 0.610484739297743 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/408 89/18639 0.0337078651685393 1.53990416391276 0.309082628936077 0.610484739297743 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/408 89/18639 0.0337078651685393 1.53990416391276 0.309082628936077 0.610484739297743 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0016805 dipeptidase activity 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0017110 nucleoside diphosphate phosphatase activity 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0019198 transmembrane receptor protein phosphatase activity 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0031489 myosin V binding 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0036041 long-chain fatty acid binding 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0038191 neuropilin binding 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0046965 nuclear retinoid X receptor binding 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0048038 quinone binding 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0070492 oligosaccharide binding 1/408 17/18639 0.0588235294117647 2.68728373702422 0.313685701220608 0.610484739297743 GO:0140793 histone H2AXY142 phosphatase activity 3/408 90/18639 0.0333333333333333 1.52279411764706 0.315084825983123 0.610484739297743 GO:0005080 protein kinase C binding 2/408 52/18639 0.0384615384615385 1.75707013574661 0.315559939779786 0.610484739297743 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/408 52/18639 0.0384615384615385 1.75707013574661 0.315559939779786 0.610484739297743 GO:0141108 transporter regulator activity 5/408 170/18639 0.0294117647058824 1.34364186851211 0.316003338220066 0.610484739297743 GO:0005262 calcium channel activity 4/408 131/18639 0.0305343511450382 1.39492590929502 0.322657323066831 0.610484739297743 GO:0004864 protein phosphatase inhibitor activity 2/408 53/18639 0.0377358490566038 1.72391786903441 0.323631024556695 0.610484739297743 GO:0005544 calcium-dependent phospholipid binding 2/408 53/18639 0.0377358490566038 1.72391786903441 0.323631024556695 0.610484739297743 GO:0140296 general transcription initiation factor binding 2/408 53/18639 0.0377358490566038 1.72391786903441 0.323631024556695 0.610484739297743 GO:0043178 alcohol binding 3/408 92/18639 0.0326086956521739 1.48968989769821 0.327094862239166 0.610484739297743 GO:0000400 four-way junction DNA binding 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0000900 mRNA regulatory element binding translation repressor activity 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0016854 racemase and epimerase activity 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0017075 syntaxin-1 binding 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0017128 phospholipid scramblase activity 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0030228 lipoprotein particle receptor activity 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0034185 apolipoprotein binding 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0035615 clathrin adaptor activity 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0050811 GABA receptor binding 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0098641 cadherin binding involved in cell-cell adhesion 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:1901611 phosphatidylglycerol binding 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:1990381 ubiquitin-specific protease binding 1/408 18/18639 0.0555555555555556 2.53799019607843 0.328722551929554 0.610484739297743 GO:0051287 NAD binding 2/408 54/18639 0.037037037037037 1.69199346405229 0.331677623967689 0.614484873389414 GO:0004721 phosphoprotein phosphatase activity 5/408 175/18639 0.0285714285714286 1.30525210084034 0.337569079931792 0.623892733271528 GO:0042562 hormone binding 3/408 94/18639 0.0319148936170213 1.45799436795995 0.339102541909174 0.624197580010275 GO:0098632 cell-cell adhesion mediator activity 2/408 55/18639 0.0363636363636364 1.66122994652406 0.339696946770511 0.624197580010275 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/408 19/18639 0.0526315789473684 2.40441176470588 0.343430741544115 0.624197580010275 GO:0008301 DNA binding, bending 1/408 19/18639 0.0526315789473684 2.40441176470588 0.343430741544115 0.624197580010275 GO:0015245 fatty acid transmembrane transporter activity 1/408 19/18639 0.0526315789473684 2.40441176470588 0.343430741544115 0.624197580010275 GO:0034987 immunoglobulin receptor binding 1/408 19/18639 0.0526315789473684 2.40441176470588 0.343430741544115 0.624197580010275 GO:0046624 sphingolipid transporter activity 1/408 19/18639 0.0526315789473684 2.40441176470588 0.343430741544115 0.624197580010275 GO:0140789 histone phosphatase activity 4/408 136/18639 0.0294117647058824 1.34364186851211 0.347506781125575 0.625998636090676 GO:0019212 phosphatase inhibitor activity 2/408 56/18639 0.0357142857142857 1.63156512605042 0.347686335038628 0.625998636090676 GO:0030170 pyridoxal phosphate binding 2/408 56/18639 0.0357142857142857 1.63156512605042 0.347686335038628 0.625998636090676 GO:0170055 lipid transmembrane transporter activity 2/408 56/18639 0.0357142857142857 1.63156512605042 0.347686335038628 0.625998636090676 GO:0004601 peroxidase activity 2/408 57/18639 0.0350877192982456 1.60294117647059 0.355643259687037 0.629463242401887 GO:0070279 vitamin B6 binding 2/408 57/18639 0.0350877192982456 1.60294117647059 0.355643259687037 0.629463242401887 GO:0001614 purinergic nucleotide receptor activity 1/408 20/18639 0.05 2.28419117647059 0.35781743635883 0.629463242401887 GO:0001972 retinoic acid binding 1/408 20/18639 0.05 2.28419117647059 0.35781743635883 0.629463242401887 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/408 20/18639 0.05 2.28419117647059 0.35781743635883 0.629463242401887 GO:0005326 neurotransmitter transmembrane transporter activity 1/408 20/18639 0.05 2.28419117647059 0.35781743635883 0.629463242401887 GO:0010851 cyclase regulator activity 1/408 20/18639 0.05 2.28419117647059 0.35781743635883 0.629463242401887 GO:0016502 nucleotide receptor activity 1/408 20/18639 0.05 2.28419117647059 0.35781743635883 0.629463242401887 GO:0030742 GTP-dependent protein binding 1/408 20/18639 0.05 2.28419117647059 0.35781743635883 0.629463242401887 GO:0043024 ribosomal small subunit binding 1/408 20/18639 0.05 2.28419117647059 0.35781743635883 0.629463242401887 GO:0070851 growth factor receptor binding 4/408 139/18639 0.0287769784172662 1.31464240372408 0.362437021024235 0.631060528950826 GO:0004725 protein tyrosine phosphatase activity 3/408 98/18639 0.0306122448979592 1.3984843937575 0.36306573465705 0.631060528950826 GO:0061980 regulatory RNA binding 2/408 58/18639 0.0344827586206897 1.57530425963489 0.363565316129274 0.631060528950826 GO:0015459 potassium channel regulator activity 2/408 59/18639 0.0338983050847458 1.54860418743769 0.371450220062063 0.631060528950826 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/408 59/18639 0.0338983050847458 1.54860418743769 0.371450220062063 0.631060528950826 GO:0031593 polyubiquitin modification-dependent protein binding 2/408 59/18639 0.0338983050847458 1.54860418743769 0.371450220062063 0.631060528950826 GO:0070063 RNA polymerase binding 2/408 59/18639 0.0338983050847458 1.54860418743769 0.371450220062063 0.631060528950826 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/408 21/18639 0.0476190476190476 2.17542016806723 0.371889646787188 0.631060528950826 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/408 21/18639 0.0476190476190476 2.17542016806723 0.371889646787188 0.631060528950826 GO:0005123 death receptor binding 1/408 21/18639 0.0476190476190476 2.17542016806723 0.371889646787188 0.631060528950826 GO:0008373 sialyltransferase activity 1/408 21/18639 0.0476190476190476 2.17542016806723 0.371889646787188 0.631060528950826 GO:0010314 phosphatidylinositol-5-phosphate binding 1/408 21/18639 0.0476190476190476 2.17542016806723 0.371889646787188 0.631060528950826 GO:0035613 RNA stem-loop binding 1/408 21/18639 0.0476190476190476 2.17542016806723 0.371889646787188 0.631060528950826 GO:0051428 peptide hormone receptor binding 1/408 21/18639 0.0476190476190476 2.17542016806723 0.371889646787188 0.631060528950826 GO:0070182 DNA polymerase binding 1/408 21/18639 0.0476190476190476 2.17542016806723 0.371889646787188 0.631060528950826 GO:0140312 cargo adaptor activity 1/408 21/18639 0.0476190476190476 2.17542016806723 0.371889646787188 0.631060528950826 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/408 60/18639 0.0333333333333333 1.52279411764706 0.379295803374112 0.641265027656006 GO:0008093 cytoskeletal anchor activity 1/408 22/18639 0.0454545454545455 2.07653743315508 0.385654230744156 0.641265027656006 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/408 22/18639 0.0454545454545455 2.07653743315508 0.385654230744156 0.641265027656006 GO:0031683 G-protein beta/gamma-subunit complex binding 1/408 22/18639 0.0454545454545455 2.07653743315508 0.385654230744156 0.641265027656006 GO:0033691 sialic acid binding 1/408 22/18639 0.0454545454545455 2.07653743315508 0.385654230744156 0.641265027656006 GO:0061133 endopeptidase activator activity 1/408 22/18639 0.0454545454545455 2.07653743315508 0.385654230744156 0.641265027656006 GO:0070034 telomerase RNA binding 1/408 22/18639 0.0454545454545455 2.07653743315508 0.385654230744156 0.641265027656006 GO:0140517 protein-RNA adaptor activity 1/408 22/18639 0.0454545454545455 2.07653743315508 0.385654230744156 0.641265027656006 GO:0015026 coreceptor activity 2/408 61/18639 0.0327868852459016 1.49783027965284 0.38710001017566 0.641265027656006 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/408 61/18639 0.0327868852459016 1.49783027965284 0.38710001017566 0.641265027656006 GO:0019905 syntaxin binding 2/408 61/18639 0.0327868852459016 1.49783027965284 0.38710001017566 0.641265027656006 GO:0004722 protein serine/threonine phosphatase activity 3/408 103/18639 0.029126213592233 1.33059680182753 0.392814253583786 0.6444703725576 GO:0000295 adenine nucleotide transmembrane transporter activity 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0003887 DNA-directed DNA polymerase activity 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0004602 glutathione peroxidase activity 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0016493 C-C chemokine receptor activity 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0016849 phosphorus-oxygen lyase activity 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0042171 lysophosphatidic acid acyltransferase activity 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0043274 phospholipase binding 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0070577 lysine-acetylated histone binding 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0071617 lysophospholipid acyltransferase activity 1/408 23/18639 0.0434782608695652 1.98625319693095 0.399117896955489 0.6444703725576 GO:0015085 calcium ion transmembrane transporter activity 4/408 147/18639 0.0272108843537415 1.24309723889556 0.402137737371118 0.647484088019132 GO:0019902 phosphatase binding 5/408 190/18639 0.0263157894736842 1.20220588235294 0.402672633618157 0.647484088019132 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/408 24/18639 0.0416666666666667 1.90349264705882 0.412287208195399 0.65200884265128 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/408 24/18639 0.0416666666666667 1.90349264705882 0.412287208195399 0.65200884265128 GO:0005315 phosphate transmembrane transporter activity 1/408 24/18639 0.0416666666666667 1.90349264705882 0.412287208195399 0.65200884265128 GO:0005540 hyaluronic acid binding 1/408 24/18639 0.0416666666666667 1.90349264705882 0.412287208195399 0.65200884265128 GO:0015295 solute:proton symporter activity 1/408 24/18639 0.0416666666666667 1.90349264705882 0.412287208195399 0.65200884265128 GO:0030215 semaphorin receptor binding 1/408 24/18639 0.0416666666666667 1.90349264705882 0.412287208195399 0.65200884265128 GO:0035035 histone acetyltransferase binding 1/408 24/18639 0.0416666666666667 1.90349264705882 0.412287208195399 0.65200884265128 GO:0140033 acetylation-dependent protein binding 1/408 24/18639 0.0416666666666667 1.90349264705882 0.412287208195399 0.65200884265128 GO:0019843 rRNA binding 2/408 65/18639 0.0307692307692308 1.40565610859729 0.417865669640653 0.652716001069919 GO:0160215 deacylase activity 2/408 65/18639 0.0307692307692308 1.40565610859729 0.417865669640653 0.652716001069919 GO:0004843 cysteine-type deubiquitinase activity 3/408 108/18639 0.0277777777777778 1.26899509803922 0.422196956985252 0.652716001069919 GO:0003707 nuclear steroid receptor activity 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0005251 delayed rectifier potassium channel activity 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0008139 nuclear localization sequence binding 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0008483 transaminase activity 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0015662 P-type ion transporter activity 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0017025 TBP-class protein binding 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0019707 protein-cysteine S-acyltransferase activity 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0042974 nuclear retinoic acid receptor binding 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0140358 P-type transmembrane transporter activity 1/408 25/18639 0.04 1.82735294117647 0.42516858445413 0.652716001069919 GO:0031267 small GTPase binding 7/408 283/18639 0.0247349823321555 1.12998856786531 0.425499348806988 0.652716001069919 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/408 67/18639 0.0298507462686567 1.36369622475856 0.432954407010362 0.653245701810009 GO:0001637 G protein-coupled chemoattractant receptor activity 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0004435 phosphatidylinositol phospholipase C activity 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0004950 chemokine receptor activity 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0005227 calcium-activated cation channel activity 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0008143 poly(A) binding 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0008157 protein phosphatase 1 binding 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0015216 purine nucleotide transmembrane transporter activity 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0030507 spectrin binding 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0050681 nuclear androgen receptor binding 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0050750 low-density lipoprotein particle receptor binding 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0097602 cullin family protein binding 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0120014 phospholipid transfer activity 1/408 26/18639 0.0384615384615385 1.75707013574661 0.437768306036955 0.653245701810009 GO:0030145 manganese ion binding 2/408 68/18639 0.0294117647058824 1.34364186851211 0.440420058940844 0.655926573218695 GO:0008395 steroid hydroxylase activity 1/408 27/18639 0.037037037037037 1.69199346405229 0.450092516596077 0.66516562664584 GO:0015252 proton channel activity 1/408 27/18639 0.037037037037037 1.69199346405229 0.450092516596077 0.66516562664584 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/408 27/18639 0.037037037037037 1.69199346405229 0.450092516596077 0.66516562664584 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/408 27/18639 0.037037037037037 1.69199346405229 0.450092516596077 0.66516562664584 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/408 70/18639 0.0285714285714286 1.30525210084034 0.455187488194922 0.669721982057058 GO:0097110 scaffold protein binding 2/408 70/18639 0.0285714285714286 1.30525210084034 0.455187488194922 0.669721982057058 GO:0045499 chemorepellent activity 1/408 28/18639 0.0357142857142857 1.63156512605042 0.462147226096872 0.669721982057058 GO:0046875 ephrin receptor binding 1/408 28/18639 0.0357142857142857 1.63156512605042 0.462147226096872 0.669721982057058 GO:0046966 nuclear thyroid hormone receptor binding 1/408 28/18639 0.0357142857142857 1.63156512605042 0.462147226096872 0.669721982057058 GO:0051393 alpha-actinin binding 1/408 28/18639 0.0357142857142857 1.63156512605042 0.462147226096872 0.669721982057058 GO:0051537 2 iron, 2 sulfur cluster binding 1/408 28/18639 0.0357142857142857 1.63156512605042 0.462147226096872 0.669721982057058 GO:0097718 disordered domain specific binding 1/408 28/18639 0.0357142857142857 1.63156512605042 0.462147226096872 0.669721982057058 GO:0001221 transcription coregulator binding 3/408 115/18639 0.0260869565217391 1.19175191815857 0.462475780599071 0.669721982057058 GO:0101005 deubiquitinase activity 3/408 115/18639 0.0260869565217391 1.19175191815857 0.462475780599071 0.669721982057058 GO:0003714 transcription corepressor activity 5/408 204/18639 0.0245098039215686 1.11970155709343 0.462780509113743 0.669721982057058 GO:0099106 ion channel regulator activity 4/408 160/18639 0.025 1.14209558823529 0.465520150250804 0.672417994806716 GO:0005261 monoatomic cation channel activity 8/408 341/18639 0.0234604105571848 1.07176125582198 0.47149144739094 0.676928652929564 GO:0003785 actin monomer binding 1/408 29/18639 0.0344827586206897 1.57530425963489 0.473938313719916 0.676928652929564 GO:0004629 phospholipase C activity 1/408 29/18639 0.0344827586206897 1.57530425963489 0.473938313719916 0.676928652929564 GO:0016417 S-acyltransferase activity 1/408 29/18639 0.0344827586206897 1.57530425963489 0.473938313719916 0.676928652929564 GO:0035250 UDP-galactosyltransferase activity 1/408 29/18639 0.0344827586206897 1.57530425963489 0.473938313719916 0.676928652929564 GO:0106222 lncRNA binding 1/408 29/18639 0.0344827586206897 1.57530425963489 0.473938313719916 0.676928652929564 GO:0005516 calmodulin binding 5/408 207/18639 0.0241545893719807 1.10347399829497 0.475451726618964 0.677828019176106 GO:0003684 damaged DNA binding 2/408 74/18639 0.027027027027027 1.23469793322735 0.484035761794001 0.683223236783523 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/408 30/18639 0.0333333333333333 1.52279411764706 0.485471530700156 0.683223236783523 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/408 30/18639 0.0333333333333333 1.52279411764706 0.485471530700156 0.683223236783523 GO:0015215 nucleotide transmembrane transporter activity 1/408 30/18639 0.0333333333333333 1.52279411764706 0.485471530700156 0.683223236783523 GO:0022839 monoatomic ion-gated channel activity 1/408 30/18639 0.0333333333333333 1.52279411764706 0.485471530700156 0.683223236783523 GO:0031624 ubiquitin conjugating enzyme binding 1/408 30/18639 0.0333333333333333 1.52279411764706 0.485471530700156 0.683223236783523 GO:0033612 receptor serine/threonine kinase binding 1/408 30/18639 0.0333333333333333 1.52279411764706 0.485471530700156 0.683223236783523 GO:0003697 single-stranded DNA binding 3/408 121/18639 0.0247933884297521 1.13265678172095 0.496005311720033 0.6927439452386 GO:0008327 methyl-CpG binding 1/408 31/18639 0.032258064516129 1.47367172675522 0.496752503104603 0.6927439452386 GO:0016411 acylglycerol O-acyltransferase activity 1/408 31/18639 0.032258064516129 1.47367172675522 0.496752503104603 0.6927439452386 GO:0070273 phosphatidylinositol-4-phosphate binding 1/408 31/18639 0.032258064516129 1.47367172675522 0.496752503104603 0.6927439452386 GO:0070325 lipoprotein particle receptor binding 1/408 31/18639 0.032258064516129 1.47367172675522 0.496752503104603 0.6927439452386 GO:0098631 cell adhesion mediator activity 2/408 76/18639 0.0263157894736842 1.20220588235294 0.49810146840661 0.693011433095625 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/408 122/18639 0.0245901639344262 1.12337270973963 0.50149244894928 0.693011433095625 GO:0016247 channel regulator activity 4/408 168/18639 0.0238095238095238 1.08771008403361 0.503331157355842 0.693011433095625 GO:0003779 actin binding 10/408 443/18639 0.0225733634311512 1.03123755145399 0.505692966266067 0.693011433095625 GO:0030695 GTPase regulator activity 11/408 489/18639 0.0224948875255624 1.02765247203176 0.506413740558737 0.693011433095625 GO:0008378 galactosyltransferase activity 1/408 32/18639 0.03125 1.42761948529412 0.507786734549858 0.693011433095625 GO:0022884 macromolecule transmembrane transporter activity 1/408 32/18639 0.03125 1.42761948529412 0.507786734549858 0.693011433095625 GO:0030515 snoRNA binding 1/408 32/18639 0.03125 1.42761948529412 0.507786734549858 0.693011433095625 GO:0031369 translation initiation factor binding 1/408 32/18639 0.03125 1.42761948529412 0.507786734549858 0.693011433095625 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/408 32/18639 0.03125 1.42761948529412 0.507786734549858 0.693011433095625 GO:0043425 bHLH transcription factor binding 1/408 32/18639 0.03125 1.42761948529412 0.507786734549858 0.693011433095625 GO:0070717 poly-purine tract binding 1/408 32/18639 0.03125 1.42761948529412 0.507786734549858 0.693011433095625 GO:0060589 nucleoside-triphosphatase regulator activity 11/408 490/18639 0.0224489795918367 1.02555522208884 0.509151494512055 0.693639780267755 GO:0003730 mRNA 3'-UTR binding 6/408 262/18639 0.0229007633587786 1.04619443197126 0.51309871550771 0.697777863110662 GO:0019239 deaminase activity 1/408 33/18639 0.0303030303030303 1.38435828877005 0.518579608860798 0.70398329202873 GO:0005216 monoatomic ion channel activity 10/408 448/18639 0.0223214285714286 1.01972820378151 0.520011955897814 0.704680512674247 GO:0140030 modification-dependent protein binding 4/408 173/18639 0.023121387283237 1.05627337640258 0.526358912929733 0.708285537834484 GO:0019783 ubiquitin-like protein peptidase activity 3/408 127/18639 0.0236220472440945 1.07914543770264 0.528458635225317 0.708285537834484 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/408 34/18639 0.0294117647058824 1.34364186851211 0.529136392671655 0.708285537834484 GO:0016831 carboxy-lyase activity 1/408 34/18639 0.0294117647058824 1.34364186851211 0.529136392671655 0.708285537834484 GO:0019825 oxygen binding 1/408 34/18639 0.0294117647058824 1.34364186851211 0.529136392671655 0.708285537834484 GO:0030332 cyclin binding 1/408 34/18639 0.0294117647058824 1.34364186851211 0.529136392671655 0.708285537834484 GO:0051427 hormone receptor binding 1/408 34/18639 0.0294117647058824 1.34364186851211 0.529136392671655 0.708285537834484 GO:0031490 chromatin DNA binding 3/408 128/18639 0.0234375 1.07071461397059 0.533754297745417 0.711981819775191 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/408 128/18639 0.0234375 1.07071461397059 0.533754297745417 0.711981819775191 GO:0035591 signaling adaptor activity 3/408 129/18639 0.0232558139534884 1.06241450068399 0.5390163161229 0.712164434636106 GO:0005154 epidermal growth factor receptor binding 1/408 35/18639 0.0285714285714286 1.30525210084034 0.539462237970766 0.712164434636106 GO:0016229 steroid dehydrogenase activity 1/408 35/18639 0.0285714285714286 1.30525210084034 0.539462237970766 0.712164434636106 GO:0034061 DNA polymerase activity 1/408 35/18639 0.0285714285714286 1.30525210084034 0.539462237970766 0.712164434636106 GO:0043015 gamma-tubulin binding 1/408 35/18639 0.0285714285714286 1.30525210084034 0.539462237970766 0.712164434636106 GO:0061631 ubiquitin conjugating enzyme activity 1/408 35/18639 0.0285714285714286 1.30525210084034 0.539462237970766 0.712164434636106 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/408 130/18639 0.0230769230769231 1.05424208144796 0.544244254505403 0.716860876837895 GO:0004033 aldo-keto reductase (NADPH) activity 1/408 36/18639 0.0277777777777778 1.26899509803922 0.549562184590199 0.716860876837895 GO:0004190 aspartic-type endopeptidase activity 1/408 36/18639 0.0277777777777778 1.26899509803922 0.549562184590199 0.716860876837895 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/408 36/18639 0.0277777777777778 1.26899509803922 0.549562184590199 0.716860876837895 GO:0016409 palmitoyltransferase activity 1/408 36/18639 0.0277777777777778 1.26899509803922 0.549562184590199 0.716860876837895 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/408 36/18639 0.0277777777777778 1.26899509803922 0.549562184590199 0.716860876837895 GO:0045505 dynein intermediate chain binding 1/408 36/18639 0.0277777777777778 1.26899509803922 0.549562184590199 0.716860876837895 GO:0004860 protein kinase inhibitor activity 2/408 84/18639 0.0238095238095238 1.08771008403361 0.55184616409126 0.718618009945665 GO:0016791 phosphatase activity 6/408 273/18639 0.021978021978022 1.00404007756949 0.553326904829934 0.719324976278915 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3/408 132/18639 0.0227272727272727 1.03826871657754 0.554596253318823 0.719755205237796 GO:0042805 actinin binding 1/408 37/18639 0.027027027027027 1.23469793322735 0.559441162641438 0.723594218795924 GO:0070001 aspartic-type peptidase activity 1/408 37/18639 0.027027027027027 1.23469793322735 0.559441162641438 0.723594218795924 GO:0051087 protein-folding chaperone binding 3/408 134/18639 0.0223880597014925 1.02277216856892 0.564807223415008 0.729304950099851 GO:0000287 magnesium ion binding 5/408 230/18639 0.0217391304347826 0.993126598465473 0.568663155050637 0.72993773258696 GO:0005109 frizzled binding 1/408 38/18639 0.0263157894736842 1.20220588235294 0.569103994898308 0.72993773258696 GO:0005501 retinoid binding 1/408 38/18639 0.0263157894736842 1.20220588235294 0.569103994898308 0.72993773258696 GO:0019840 isoprenoid binding 1/408 38/18639 0.0263157894736842 1.20220588235294 0.569103994898308 0.72993773258696 GO:0016779 nucleotidyltransferase activity 3/408 136/18639 0.0220588235294118 1.00773140138408 0.574874413171484 0.734881124837547 GO:0099094 ligand-gated monoatomic cation channel activity 3/408 136/18639 0.0220588235294118 1.00773140138408 0.574874413171484 0.734881124837547 GO:0000217 DNA secondary structure binding 1/408 39/18639 0.0256410256410256 1.17138009049774 0.578555399128268 0.737129553374388 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/408 39/18639 0.0256410256410256 1.17138009049774 0.578555399128268 0.737129553374388 GO:0004532 RNA exonuclease activity 1/408 40/18639 0.025 1.14209558823529 0.587799990373196 0.743964674284227 GO:0015144 carbohydrate transmembrane transporter activity 1/408 40/18639 0.025 1.14209558823529 0.587799990373196 0.743964674284227 GO:0071855 neuropeptide receptor binding 1/408 40/18639 0.025 1.14209558823529 0.587799990373196 0.743964674284227 GO:0071949 FAD binding 1/408 40/18639 0.025 1.14209558823529 0.587799990373196 0.743964674284227 GO:0019210 kinase inhibitor activity 2/408 90/18639 0.0222222222222222 1.01519607843137 0.589417217663145 0.744782546865951 GO:0046943 carboxylic acid transmembrane transporter activity 4/408 188/18639 0.0212765957446809 0.971996245306633 0.592118685072027 0.746965512253693 GO:0005342 organic acid transmembrane transporter activity 4/408 189/18639 0.0211640211640212 0.966853408029879 0.596308545042795 0.748003318953655 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/408 41/18639 0.024390243902439 1.11423959827834 0.596842283180752 0.748003318953655 GO:0042169 SH2 domain binding 1/408 41/18639 0.024390243902439 1.11423959827834 0.596842283180752 0.748003318953655 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/408 41/18639 0.024390243902439 1.11423959827834 0.596842283180752 0.748003318953655 GO:0052689 carboxylic ester hydrolase activity 2/408 92/18639 0.0217391304347826 0.993126598465473 0.601410438218488 0.752498868048255 GO:0019787 ubiquitin-like protein transferase activity 10/408 479/18639 0.0208768267223382 0.953733267837406 0.605331276408369 0.754158594374884 GO:0019894 kinesin binding 1/408 42/18639 0.0238095238095238 1.08771008403361 0.60568669378739 0.754158594374884 GO:0051879 Hsp90 protein binding 1/408 42/18639 0.0238095238095238 1.08771008403361 0.60568669378739 0.754158594374884 GO:0015631 tubulin binding 8/408 385/18639 0.0207792207792208 0.949274255156608 0.608978672314038 0.757028592649704 GO:0016410 N-acyltransferase activity 2/408 94/18639 0.0212765957446809 0.971996245306633 0.613137916942821 0.760965667144246 GO:0008194 UDP-glycosyltransferase activity 3/408 145/18639 0.0206896551724138 0.945182555780933 0.618338654220023 0.765641831102965 GO:0008276 protein methyltransferase activity 2/408 95/18639 0.0210526315789474 0.961764705882353 0.61890213205194 0.765641831102965 GO:0001046 core promoter sequence-specific DNA binding 1/408 44/18639 0.0227272727272727 1.03826871657754 0.622799054555653 0.769222020683069 GO:0004896 cytokine receptor activity 2/408 96/18639 0.0208333333333333 0.951746323529412 0.624600125035089 0.770206263507899 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/408 45/18639 0.0222222222222222 1.01519607843137 0.631075364625096 0.776941901552887 GO:0005249 voltage-gated potassium channel activity 2/408 98/18639 0.0204081632653061 0.932322929171669 0.635797990181218 0.78025129355039 GO:0008170 N-methyltransferase activity 2/408 98/18639 0.0204081632653061 0.932322929171669 0.635797990181218 0.78025129355039 GO:0030291 protein serine/threonine kinase inhibitor activity 1/408 46/18639 0.0217391304347826 0.993126598465473 0.639170516353232 0.783137038407235 GO:0000510 H3-H4 histone complex chaperone activity 3/408 151/18639 0.0198675496688742 0.907625633034671 0.645594381125318 0.785119159147572 GO:0140584 chromatin extrusion motor activity 3/408 151/18639 0.0198675496688742 0.907625633034671 0.645594381125318 0.785119159147572 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/408 151/18639 0.0198675496688742 0.907625633034671 0.645594381125318 0.785119159147572 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/408 151/18639 0.0198675496688742 0.907625633034671 0.645594381125318 0.785119159147572 GO:0003712 transcription coregulator activity 10/408 495/18639 0.0202020202020202 0.922905525846702 0.646387810234525 0.785119159147572 GO:0140938 histone H3 methyltransferase activity 1/408 47/18639 0.0212765957446809 0.971996245306633 0.647088465545287 0.785119159147572 GO:0016755 aminoacyltransferase activity 10/408 496/18639 0.0201612903225806 0.921044829222011 0.648875459862443 0.785119159147572 GO:0015616 DNA translocase activity 3/408 152/18639 0.0197368421052632 0.901654411764706 0.650000868394665 0.785119159147572 GO:0140674 ATP-dependent histone chaperone activity 3/408 152/18639 0.0197368421052632 0.901654411764706 0.650000868394665 0.785119159147572 GO:0004842 ubiquitin-protein transferase activity 9/408 449/18639 0.0200445434298441 0.915711384776628 0.65248509874994 0.786004653783117 GO:0061775 cohesin loader activity 3/408 153/18639 0.0196078431372549 0.89576124567474 0.654368287527483 0.786004653783117 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/408 48/18639 0.0208333333333333 0.951746323529412 0.654833081834956 0.786004653783117 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/408 48/18639 0.0208333333333333 0.951746323529412 0.654833081834956 0.786004653783117 GO:0015605 organophosphate ester transmembrane transporter activity 1/408 50/18639 0.02 0.913676470588235 0.669817374579193 0.802734259847252 GO:0140658 ATP-dependent chromatin remodeler activity 3/408 158/18639 0.0189873417721519 0.867414370811616 0.675618515203701 0.806379466559988 GO:0005048 signal sequence binding 1/408 51/18639 0.0196078431372549 0.89576124567474 0.677064376094696 0.806379466559988 GO:0005272 sodium channel activity 1/408 51/18639 0.0196078431372549 0.89576124567474 0.677064376094696 0.806379466559988 GO:0016830 carbon-carbon lyase activity 1/408 51/18639 0.0196078431372549 0.89576124567474 0.677064376094696 0.806379466559988 GO:0106310 protein serine kinase activity 7/408 361/18639 0.0193905817174515 0.885835913312693 0.679486660260236 0.808009718480001 GO:0003689 DNA clamp loader activity 3/408 160/18639 0.01875 0.856571691176471 0.683844766416362 0.809791851317773 GO:0015079 potassium ion transmembrane transporter activity 3/408 160/18639 0.01875 0.856571691176471 0.683844766416362 0.809791851317773 GO:0030159 signaling receptor complex adaptor activity 1/408 52/18639 0.0192307692307692 0.878535067873303 0.684152698375381 0.809791851317773 GO:0008146 sulfotransferase activity 1/408 53/18639 0.0188679245283019 0.861958934517203 0.691085807487279 0.816737772484966 GO:0004222 metalloendopeptidase activity 2/408 110/18639 0.0181818181818182 0.830614973262032 0.697533840603539 0.823089931912176 GO:0015081 sodium ion transmembrane transporter activity 3/408 164/18639 0.0182926829268293 0.835679698708752 0.699829313707803 0.823265465665468 GO:0140713 histone chaperone activity 3/408 164/18639 0.0182926829268293 0.835679698708752 0.699829313707803 0.823265465665468 GO:0008374 O-acyltransferase activity 1/408 55/18639 0.0181818181818182 0.830614973262032 0.704499874472452 0.826242312356477 GO:0008514 organic anion transmembrane transporter activity 5/408 269/18639 0.0185873605947955 0.849141701290182 0.704514305451285 0.826242312356477 GO:0005200 structural constituent of cytoskeleton 2/408 112/18639 0.0178571428571429 0.81578256302521 0.70693780533348 0.827818773573709 GO:0061659 ubiquitin-like protein ligase activity 7/408 372/18639 0.0188172043010753 0.859641840607211 0.709101130630511 0.829086230478051 GO:0016874 ligase activity 3/408 167/18639 0.0179640718562874 0.820667488552307 0.711410403083364 0.830520211818783 GO:0005201 extracellular matrix structural constituent 3/408 168/18639 0.0178571428571429 0.81578256302521 0.715193662096592 0.833667992139948 GO:0035401 histone H3Y41 kinase activity 2/408 115/18639 0.0173913043478261 0.794501278772379 0.720585837974217 0.837408087463977 GO:0140801 histone H2AXY142 kinase activity 2/408 115/18639 0.0173913043478261 0.794501278772379 0.720585837974217 0.837408087463977 GO:0009055 electron transfer activity 2/408 116/18639 0.0172413793103448 0.787652129817444 0.725014836693302 0.839243613024512 GO:0015294 solute:monoatomic cation symporter activity 2/408 116/18639 0.0172413793103448 0.787652129817444 0.725014836693302 0.839243613024512 GO:0008017 microtubule binding 5/408 276/18639 0.0181159420289855 0.827605498721228 0.725447868885595 0.839243613024512 GO:0004674 protein serine/threonine kinase activity 8/408 433/18639 0.0184757505773672 0.844042928949871 0.734962758025477 0.848970535249308 GO:0003735 structural constituent of ribosome 3/408 175/18639 0.0171428571428571 0.783151260504202 0.740609340824244 0.85405538932683 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/408 229/18639 0.0174672489082969 0.797970716670948 0.741591772218603 0.85405538932683 GO:0005085 guanyl-nucleotide exchange factor activity 4/408 230/18639 0.0173913043478261 0.794501278772379 0.744652455708302 0.856294503040881 GO:0015179 L-amino acid transmembrane transporter activity 1/408 62/18639 0.0161290322580645 0.736835863377609 0.747034979635102 0.857748247575035 GO:0005507 copper ion binding 1/408 63/18639 0.0158730158730159 0.725140056022409 0.752590759809989 0.861547929513824 GO:1901682 sulfur compound transmembrane transporter activity 1/408 63/18639 0.0158730158730159 0.725140056022409 0.752590759809989 0.861547929513824 GO:0005267 potassium channel activity 2/408 124/18639 0.0161290322580645 0.736835863377609 0.758348612755873 0.866845582688159 GO:0046873 metal ion transmembrane transporter activity 8/408 450/18639 0.0177777777777778 0.812156862745098 0.772228540384423 0.881397753682816 GO:0042054 histone methyltransferase activity 1/408 67/18639 0.0149253731343284 0.68184811237928 0.773622927042114 0.881677243746361 GO:0015276 ligand-gated monoatomic ion channel activity 3/408 186/18639 0.0161290322580645 0.736835863377609 0.776873410802039 0.884068109918641 GO:0022834 ligand-gated channel activity 3/408 188/18639 0.0159574468085106 0.728997183979975 0.783000429073605 0.88630389706008 GO:0140597 protein carrier chaperone 3/408 188/18639 0.0159574468085106 0.728997183979975 0.783000429073605 0.88630389706008 GO:0008080 N-acetyltransferase activity 1/408 69/18639 0.0144927536231884 0.662084398976982 0.78346028970891 0.88630389706008 GO:0016279 protein-lysine N-methyltransferase activity 1/408 69/18639 0.0144927536231884 0.662084398976982 0.78346028970891 0.88630389706008 GO:0061630 ubiquitin protein ligase activity 6/408 353/18639 0.0169971671388102 0.776495584069322 0.788134173473619 0.886456163692165 GO:0005179 hormone activity 2/408 132/18639 0.0151515151515152 0.692179144385027 0.788135126417965 0.886456163692165 GO:0016278 lysine N-methyltransferase activity 1/408 70/18639 0.0142857142857143 0.652626050420168 0.788217866542446 0.886456163692165 GO:0016782 transferase activity, transferring sulphur-containing groups 1/408 70/18639 0.0142857142857143 0.652626050420168 0.788217866542446 0.886456163692165 GO:0140104 molecular carrier activity 4/408 249/18639 0.0160642570281124 0.733876683203402 0.797661545713926 0.895763404923252 GO:0019838 growth factor binding 2/408 136/18639 0.0147058823529412 0.671820934256055 0.801782328293544 0.896555916688309 GO:0004521 RNA endonuclease activity 1/408 73/18639 0.0136986301369863 0.625805801772764 0.801874001105841 0.896555916688309 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/408 73/18639 0.0136986301369863 0.625805801772764 0.801874001105841 0.896555916688309 GO:0035064 methylated histone binding 1/408 74/18639 0.0135135135135135 0.617348966613673 0.806227949589565 0.898803542638367 GO:0048029 monosaccharide binding 1/408 74/18639 0.0135135135135135 0.617348966613673 0.806227949589565 0.898803542638367 GO:0016758 hexosyltransferase activity 3/408 197/18639 0.0152284263959391 0.695692744102717 0.808874785562991 0.900445516004084 GO:0004713 protein tyrosine kinase activity 2/408 140/18639 0.0142857142857143 0.652626050420168 0.814644830494013 0.902944742150004 GO:0051536 iron-sulfur cluster binding 1/408 76/18639 0.0131578947368421 0.601102941176471 0.814651579619039 0.902944742150004 GO:0140034 methylation-dependent protein binding 1/408 76/18639 0.0131578947368421 0.601102941176471 0.814651579619039 0.902944742150004 GO:0003724 RNA helicase activity 1/408 77/18639 0.012987012987013 0.59329640947288 0.818725390722601 0.904844920294287 GO:0051540 metal cluster binding 1/408 77/18639 0.012987012987013 0.59329640947288 0.818725390722601 0.904844920294287 GO:0022843 voltage-gated monoatomic cation channel activity 2/408 143/18639 0.013986013986014 0.638934594816948 0.823797580722555 0.908927543282798 GO:0008186 ATP-dependent activity, acting on RNA 1/408 79/18639 0.0126582278481013 0.578276247207744 0.826606993337977 0.908927543282798 GO:0015370 solute:sodium symporter activity 1/408 79/18639 0.0126582278481013 0.578276247207744 0.826606993337977 0.908927543282798 GO:0008168 methyltransferase activity 3/408 204/18639 0.0147058823529412 0.671820934256055 0.827159615660226 0.908927543282798 GO:0000049 tRNA binding 1/408 80/18639 0.0125 0.571047794117647 0.830418649949944 0.911203296869252 GO:0015293 symporter activity 2/408 146/18639 0.0136986301369863 0.625805801772764 0.832542951080521 0.912229204969656 GO:0015101 organic cation transmembrane transporter activity 1/408 81/18639 0.0123456790123457 0.563997821350762 0.834146716700331 0.912682641525183 GO:0051015 actin filament binding 3/408 209/18639 0.0143540669856459 0.655748663101604 0.839287369368119 0.91563806975541 GO:0016757 glycosyltransferase activity 4/408 267/18639 0.0149812734082397 0.684401850627892 0.839354181789123 0.91563806975541 GO:0005254 chloride channel activity 1/408 83/18639 0.0120481927710843 0.550407512402551 0.841359355606208 0.91563806975541 GO:0008094 ATP-dependent activity, acting on DNA 3/408 210/18639 0.0142857142857143 0.652626050420168 0.841622997623943 0.91563806975541 GO:0004527 exonuclease activity 1/408 84/18639 0.0119047619047619 0.543855042016807 0.844847466347352 0.917844202108242 GO:0046906 tetrapyrrole binding 2/408 152/18639 0.0131578947368421 0.601102941176471 0.84886903959762 0.920908844938295 GO:0050660 flavin adenine dinucleotide binding 1/408 86/18639 0.0116279069767442 0.531207250341997 0.851595829134604 0.922562148229154 GO:0016741 transferase activity, transferring one-carbon groups 3/408 215/18639 0.013953488372093 0.637448700410397 0.852865937855983 0.92263494264533 GO:0004386 helicase activity 2/408 155/18639 0.0129032258064516 0.589468690702087 0.856478048683613 0.925237554000466 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/408 88/18639 0.0113636363636364 0.51913435828877 0.858051359846988 0.925633464138734 GO:0015103 inorganic anion transmembrane transporter activity 2/408 165/18639 0.0121212121212121 0.553743315508021 0.879382893441591 0.937720930185319 GO:0016407 acetyltransferase activity 1/408 96/18639 0.0104166666666667 0.475873161764706 0.881190630106735 0.937720930185319 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/408 167/18639 0.0119760479041916 0.547111659034871 0.88353936981327 0.937720930185319 GO:0030594 neurotransmitter receptor activity 1/408 97/18639 0.0103092783505155 0.470967252880534 0.88380478223511 0.937720930185319 GO:0005244 voltage-gated monoatomic ion channel activity 2/408 173/18639 0.0115606936416185 0.528136688201292 0.895227427715079 0.937720930185319 GO:0015171 amino acid transmembrane transporter activity 1/408 102/18639 0.00980392156862745 0.44788062283737 0.896039548538934 0.937720930185319 GO:0016887 ATP hydrolysis activity 6/408 417/18639 0.0143884892086331 0.65732120186204 0.897099371782039 0.937720930185319 GO:0005253 monoatomic anion channel activity 1/408 103/18639 0.00970873786407767 0.443532267275842 0.8983277216088 0.937720930185319 GO:0022832 voltage-gated channel activity 2/408 175/18639 0.0114285714285714 0.522100840336134 0.898874962904592 0.937720930185319 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/408 243/18639 0.0123456790123457 0.563997821350762 0.903791804061456 0.937720930185319 GO:0004497 monooxygenase activity 1/408 106/18639 0.00943396226415094 0.430979467258602 0.904895166642509 0.937720930185319 GO:0008013 beta-catenin binding 1/408 106/18639 0.00943396226415094 0.430979467258602 0.904895166642509 0.937720930185319 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0004711 ribosomal protein S6 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0035175 histone H3S10 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0035979 histone H2AXS139 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0044022 histone H3S28 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0044023 histone H4S1 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0044024 histone H2AS1 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0044025 histone H2BS14 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0072354 histone H3T3 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0072371 histone H2AS121 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0140823 histone H2BS36 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0140855 histone H3S57 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0140995 histone H2A kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0140997 histone H4 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0140998 histone H2B kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:1990244 histone H2AT120 kinase activity 3/408 245/18639 0.0122448979591837 0.559393757503001 0.906737526391054 0.937720930185319 GO:0004677 DNA-dependent protein kinase activity 3/408 246/18639 0.0121951219512195 0.557119799139168 0.908179624103802 0.937720930185319 GO:0140857 histone H3T45 kinase activity 3/408 246/18639 0.0121951219512195 0.557119799139168 0.908179624103802 0.937720930185319 GO:0035402 histone H3T11 kinase activity 3/408 247/18639 0.0121457489878543 0.554864253393665 0.90960152810675 0.937720930185319 GO:0035403 histone H3T6 kinase activity 3/408 247/18639 0.0121457489878543 0.554864253393665 0.90960152810675 0.937720930185319 GO:0004679 AMP-activated protein kinase activity 3/408 248/18639 0.0120967741935484 0.552626897533207 0.911003472932663 0.937905588911883 GO:0022836 gated channel activity 4/408 318/18639 0.0125786163522013 0.574639289678135 0.920270489604395 0.946176227247414 GO:0003713 transcription coactivator activity 3/408 256/18639 0.01171875 0.535357306985294 0.921528121615384 0.946200895955822 GO:0004540 RNA nuclease activity 1/408 121/18639 0.00826446280991736 0.377552260573651 0.931902445651589 0.954297965039744 GO:0015108 chloride transmembrane transporter activity 1/408 121/18639 0.00826446280991736 0.377552260573651 0.931902445651589 0.954297965039744 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/408 122/18639 0.00819672131147541 0.374457569913211 0.933402812979278 0.954559943406808 GO:0016829 lyase activity 2/408 200/18639 0.01 0.456838235294118 0.935511958705544 0.955442972472905 GO:0140097 catalytic activity, acting on DNA 4/408 336/18639 0.0119047619047619 0.543855042016807 0.938621421648945 0.957343923410559 GO:0004519 endonuclease activity 1/408 127/18639 0.0078740157480315 0.35971514590088 0.940424209825121 0.957908856488536 GO:0015291 secondary active transmembrane transporter activity 3/408 287/18639 0.0104529616724739 0.477531256405001 0.952423783895619 0.966176297049797 GO:0141003 histone H2AX kinase activity 4/408 354/18639 0.0112994350282486 0.516201395812562 0.953055804138464 0.966176297049797 GO:0140767 enzyme-substrate adaptor activity 1/408 139/18639 0.00719424460431655 0.32866060093102 0.954407931768059 0.966176297049797 GO:0045182 translation regulator activity 4/408 356/18639 0.0112359550561798 0.513301387970919 0.954450948090192 0.966176297049797 GO:0140996 histone H3 kinase activity 4/408 357/18639 0.0112044817927171 0.511863568956995 0.955134136758891 0.966176297049797 GO:0035173 histone kinase activity 4/408 360/18639 0.0111111111111111 0.507598039215686 0.957127543942323 0.966176297049797 GO:0020037 heme binding 1/408 142/18639 0.00704225352112676 0.321717067108534 0.95735852119667 0.966176297049797 GO:0008509 monoatomic anion transmembrane transporter activity 1/408 149/18639 0.00671140939597315 0.306602842479274 0.96352343204289 0.971120200232453 GO:0140098 catalytic activity, acting on RNA 4/408 387/18639 0.0103359173126615 0.47218422252622 0.971721779409225 0.978097906570703 GO:0042393 histone binding 2/408 247/18639 0.00809716599190283 0.369909502262443 0.973110319333817 0.978211815110141 GO:0016853 isomerase activity 1/408 180/18639 0.00555555555555556 0.253799019607843 0.981745774154409 0.984716958475602 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/408 181/18639 0.00552486187845304 0.252396815079623 0.982149248023253 0.984716958475602 GO:0004518 nuclease activity 1/408 209/18639 0.00478468899521531 0.218582887700535 0.990457831397469 0.991750857287022 GO:0030371 translation repressor activity 2/408 329/18639 0.0060790273556231 0.277713212944752 0.994524261930014 0.994524261930014