ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0061775 cohesin loader activity 36/1725 153/18639 0.235294117647059 2.54240409207161 1.2247701928544e-07 3.94256701566682e-05 GO:0008094 ATP-dependent activity, acting on DNA 44/1725 210/18639 0.20952380952381 2.26395031055901 1.91235152038617e-07 3.94256701566682e-05 GO:0140097 catalytic activity, acting on DNA 61/1725 336/18639 0.181547619047619 1.96166149068323 2.2870389464493e-07 3.94256701566682e-05 GO:0000510 H3-H4 histone complex chaperone activity 35/1725 151/18639 0.231788079470199 2.50452058738842 2.69371385296546e-07 3.94256701566682e-05 GO:0140584 chromatin extrusion motor activity 35/1725 151/18639 0.231788079470199 2.50452058738842 2.69371385296546e-07 3.94256701566682e-05 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 35/1725 151/18639 0.231788079470199 2.50452058738842 2.69371385296546e-07 3.94256701566682e-05 GO:0140849 ATP-dependent H2AZ histone chaperone activity 35/1725 151/18639 0.231788079470199 2.50452058738842 2.69371385296546e-07 3.94256701566682e-05 GO:0140658 ATP-dependent chromatin remodeler activity 36/1725 158/18639 0.227848101265823 2.46194826637314 2.87206175530836e-07 3.94256701566682e-05 GO:0015616 DNA translocase activity 35/1725 152/18639 0.230263157894737 2.48804347826087 3.19236195600552e-07 3.94256701566682e-05 GO:0140674 ATP-dependent histone chaperone activity 35/1725 152/18639 0.230263157894737 2.48804347826087 3.19236195600552e-07 3.94256701566682e-05 GO:0003689 DNA clamp loader activity 35/1725 160/18639 0.21875 2.36364130434783 1.16100341514089e-06 0.000130349019790818 GO:0005201 extracellular matrix structural constituent 36/1725 168/18639 0.214285714285714 2.31540372670807 1.3794652309125e-06 0.000141969963348078 GO:0140713 histone chaperone activity 35/1725 164/18639 0.213414634146341 2.3059915164369 2.12236703814618e-06 0.000201624868623887 GO:0003779 actin binding 70/1725 443/18639 0.158013544018059 1.70737069388556 6.10610034256846e-06 0.000538645280219432 GO:0140098 catalytic activity, acting on RNA 63/1725 387/18639 0.162790697674419 1.7589888776542 6.7021975442166e-06 0.000551814264473834 GO:0030983 mismatched DNA binding 8/1725 14/18639 0.571428571428571 6.1744099378882 9.54993984639383e-06 0.000737135981893524 GO:0016887 ATP hydrolysis activity 66/1725 417/18639 0.158273381294964 1.71017829214889 1.05624184315552e-05 0.00076732863311592 GO:0003724 RNA helicase activity 20/1725 77/18639 0.25974025974026 2.80654997176736 1.60828521230815e-05 0.00110346235400031 GO:0140597 protein carrier chaperone 36/1725 188/18639 0.191489361702128 2.0690841813136 2.00482822246654e-05 0.00130313834460325 GO:0008186 ATP-dependent activity, acting on RNA 20/1725 79/18639 0.253164556962025 2.73549807374794 2.41897508174326e-05 0.00149371711297646 GO:0030020 extracellular matrix structural constituent conferring tensile strength 14/1725 44/18639 0.318181818181818 3.43802371541502 2.55980000420906e-05 0.00150540619295152 GO:0004386 helicase activity 30/1725 155/18639 0.193548387096774 2.09133239831697 7.75926564169092e-05 0.00435576957613104 GO:0140612 DNA damage sensor activity 9/1725 24/18639 0.375 4.05195652173913 0.000176017611450645 0.00945138044093683 GO:0051015 actin filament binding 36/1725 209/18639 0.172248803827751 1.86118577075099 0.000194900018530995 0.0100292301202408 GO:0140664 ATP-dependent DNA damage sensor activity 8/1725 20/18639 0.4 4.32208695652174 0.000241122052892387 0.0119114294128839 GO:0008168 methyltransferase activity 34/1725 204/18639 0.166666666666667 1.80086956521739 0.000538556074847255 0.0255814135552446 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 29/1725 167/18639 0.173652694610778 1.87635511585525 0.000681106580763736 0.0308805333961539 GO:0016741 transferase activity, transferring one-carbon groups 35/1725 215/18639 0.162790697674419 1.7589888776542 0.00070012545351604 0.0308805333961539 GO:0140104 molecular carrier activity 39/1725 249/18639 0.156626506024096 1.6923834468308 0.000779139048530956 0.0331805767219217 GO:0005178 integrin binding 28/1725 161/18639 0.173913043478261 1.87916824196597 0.000815009925929711 0.0335512419507731 GO:0001618 virus receptor activity 17/1725 81/18639 0.209876543209877 2.2677616747182 0.00103067829901315 0.0410608935252013 GO:0140272 exogenous protein binding 17/1725 82/18639 0.207317073170732 2.24010604453871 0.00119015716522121 0.0459326280952561 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 40/1725 268/18639 0.149253731343284 1.61271901362751 0.00171644488858573 0.0642366496182842 GO:0140299 molecular sensor activity 15/1725 71/18639 0.211267605633803 2.28279240661359 0.00185659304058843 0.066417626336556 GO:0001217 DNA-binding transcription repressor activity 41/1725 278/18639 0.147482014388489 1.5935752267751 0.00190270190324237 0.066417626336556 GO:0048185 activin binding 5/1725 11/18639 0.454545454545455 4.91146245059288 0.00193606036284698 0.066417626336556 GO:0140101 catalytic activity, acting on a tRNA 24/1725 139/18639 0.172661870503597 1.86564904598061 0.00204855987838435 0.0683776067514777 GO:0005024 transforming growth factor beta receptor activity 6/1725 16/18639 0.375 4.05195652173913 0.00220587800364178 0.071691035118358 GO:0004519 endonuclease activity 22/1725 127/18639 0.173228346456693 1.87176994180075 0.00294944591248565 0.0933991205620456 GO:0016779 nucleotidyltransferase activity 23/1725 136/18639 0.169117647058824 1.82735294117647 0.00329151830295266 0.0991469537596715 GO:0019838 growth factor binding 23/1725 136/18639 0.169117647058824 1.82735294117647 0.00329151830295266 0.0991469537596715 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 6/1725 18/18639 0.333333333333333 3.60173913043478 0.00435160924150567 0.126333935454718 GO:0097110 scaffold protein binding 14/1725 70/18639 0.2 2.16104347826087 0.00439867143688491 0.126333935454718 GO:0004033 aldo-keto reductase (NADPH) activity 9/1725 36/18639 0.25 2.70130434782609 0.00458749236660064 0.126455754032405 GO:0070123 transforming growth factor beta receptor activity, type III 5/1725 13/18639 0.384615384615385 4.15585284280936 0.0046076995396423 0.126455754032405 GO:0004518 nuclease activity 31/1725 209/18639 0.148325358851675 1.60268774703557 0.00583426569869525 0.150438675647621 GO:0003756 protein disulfide isomerase activity 6/1725 19/18639 0.315789473684211 3.41217391304348 0.00586861994459392 0.150438675647621 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 6/1725 19/18639 0.315789473684211 3.41217391304348 0.00586861994459392 0.150438675647621 GO:0003954 NADH dehydrogenase activity 10/1725 44/18639 0.227272727272727 2.45573122529644 0.005968821948772 0.150438675647621 GO:0004674 protein serine/threonine kinase activity 56/1725 433/18639 0.12933025404157 1.39744151019179 0.00651075511526152 0.160480449337063 GO:0005161 platelet-derived growth factor receptor binding 5/1725 14/18639 0.357142857142857 3.85900621118012 0.00662712786736048 0.160480449337063 GO:0005085 guanyl-nucleotide exchange factor activity 33/1725 230/18639 0.143478260869565 1.55031379962193 0.00753576653786127 0.178974455274205 GO:0005112 Notch binding 7/1725 26/18639 0.269230769230769 2.90909698996656 0.00782169650624001 0.182260286513329 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 9/1725 39/18639 0.230769230769231 2.49351170568562 0.00802925203571143 0.183631967853771 GO:0050700 CARD domain binding 5/1725 15/18639 0.333333333333333 3.60173913043478 0.00919323848384942 0.206429991410073 GO:0008239 dipeptidyl-peptidase activity 4/1725 10/18639 0.4 4.32208695652174 0.00972865619422064 0.20715328275625 GO:0016427 tRNA (cytidine) methyltransferase activity 4/1725 10/18639 0.4 4.32208695652174 0.00972865619422064 0.20715328275625 GO:0070513 death domain binding 4/1725 10/18639 0.4 4.32208695652174 0.00972865619422064 0.20715328275625 GO:0060589 nucleoside-triphosphatase regulator activity 61/1725 490/18639 0.124489795918367 1.34513930789707 0.0104307688423606 0.218338974920599 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/1725 41/18639 0.219512195121951 2.3718769883351 0.0112308682653377 0.231168705128202 GO:0022858 alanine transmembrane transporter activity 5/1725 16/18639 0.3125 3.37663043478261 0.0123693114293983 0.248827729795203 GO:0034062 5'-3' RNA polymerase activity 6/1725 22/18639 0.272727272727273 2.94687747035573 0.0126932364187027 0.248827729795203 GO:0097747 RNA polymerase activity 6/1725 22/18639 0.272727272727273 2.94687747035573 0.0126932364187027 0.248827729795203 GO:0008276 protein methyltransferase activity 16/1725 95/18639 0.168421052631579 1.81982608695652 0.0133440389105488 0.257498250851997 GO:0032404 mismatch repair complex binding 4/1725 11/18639 0.363636363636364 3.92916996047431 0.0141815680978627 0.265367221225159 GO:0180030 inositol phosphate kinase activity 4/1725 11/18639 0.363636363636364 3.92916996047431 0.0141815680978627 0.265367221225159 GO:0030695 GTPase regulator activity 60/1725 489/18639 0.122699386503067 1.32579354494532 0.014613347667904 0.269365438356141 GO:0001965 G-protein alpha-subunit binding 7/1725 30/18639 0.233333333333333 2.52121739130435 0.0174868321050832 0.304715473986542 GO:0008106 alcohol dehydrogenase (NADP+) activity 7/1725 30/18639 0.233333333333333 2.52121739130435 0.0174868321050832 0.304715473986542 GO:0008170 N-methyltransferase activity 16/1725 98/18639 0.163265306122449 1.76411712511091 0.0176581321718938 0.304715473986542 GO:0031593 polyubiquitin modification-dependent protein binding 11/1725 59/18639 0.186440677966102 2.0145320560059 0.0182288125379066 0.304715473986542 GO:0015399 primary active transmembrane transporter activity 24/1725 166/18639 0.144578313253012 1.56220010476689 0.0187395688341712 0.304715473986542 GO:0003995 acyl-CoA dehydrogenase activity 4/1725 12/18639 0.333333333333333 3.60173913043478 0.0197386541853631 0.304715473986542 GO:0005025 transforming growth factor beta receptor activity, type I 4/1725 12/18639 0.333333333333333 3.60173913043478 0.0197386541853631 0.304715473986542 GO:0005026 transforming growth factor beta receptor activity, type II 4/1725 12/18639 0.333333333333333 3.60173913043478 0.0197386541853631 0.304715473986542 GO:0005078 MAP-kinase scaffold activity 4/1725 12/18639 0.333333333333333 3.60173913043478 0.0197386541853631 0.304715473986542 GO:0016361 activin receptor activity, type I 4/1725 12/18639 0.333333333333333 3.60173913043478 0.0197386541853631 0.304715473986542 GO:0016362 activin receptor activity, type II 4/1725 12/18639 0.333333333333333 3.60173913043478 0.0197386541853631 0.304715473986542 GO:0017002 activin receptor activity 4/1725 12/18639 0.333333333333333 3.60173913043478 0.0197386541853631 0.304715473986542 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 4/1725 12/18639 0.333333333333333 3.60173913043478 0.0197386541853631 0.304715473986542 GO:0009055 electron transfer activity 18/1725 116/18639 0.155172413793103 1.67667166416792 0.0201533156537189 0.30727586212769 GO:0042887 amide transmembrane transporter activity 8/1725 38/18639 0.210526315789474 2.27478260869565 0.0209437644479643 0.315090149059063 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/1725 68/18639 0.176470588235294 1.90680306905371 0.0211760990865605 0.315090149059063 GO:0043021 ribonucleoprotein complex binding 25/1725 177/18639 0.141242937853107 1.52616064848931 0.0217649202825277 0.319485933294612 GO:0016860 intramolecular oxidoreductase activity 10/1725 53/18639 0.188679245283019 2.03872026251025 0.021988910388698 0.319485933294612 GO:0016279 protein-lysine N-methyltransferase activity 12/1725 69/18639 0.173913043478261 1.87916824196597 0.0235472482980803 0.336952138611818 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 6/1725 25/18639 0.24 2.59325217391304 0.0237367093596989 0.336952138611818 GO:0000217 DNA secondary structure binding 8/1725 39/18639 0.205128205128205 2.21645484949833 0.0242765418446747 0.34044219585668 GO:0042910 xenobiotic transmembrane transporter activity 7/1725 32/18639 0.21875 2.36364130434783 0.0245969654278568 0.34044219585668 GO:0046527 glucosyltransferase activity 5/1725 19/18639 0.263157894736842 2.84347826086957 0.0260987262554326 0.34044219585668 GO:0140036 ubiquitin-modified protein reader activity 5/1725 19/18639 0.263157894736842 2.84347826086957 0.0260987262554326 0.34044219585668 GO:0016278 lysine N-methyltransferase activity 12/1725 70/18639 0.171428571428571 1.85232298136646 0.0261078873486834 0.34044219585668 GO:0019199 transmembrane receptor protein kinase activity 13/1725 78/18639 0.166666666666667 1.80086956521739 0.0261581114471295 0.34044219585668 GO:0035673 oligopeptide transmembrane transporter activity 4/1725 13/18639 0.307692307692308 3.32468227424749 0.0264635229167945 0.34044219585668 GO:0045159 myosin II binding 4/1725 13/18639 0.307692307692308 3.32468227424749 0.0264635229167945 0.34044219585668 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 4/1725 13/18639 0.307692307692308 3.32468227424749 0.0264635229167945 0.34044219585668 GO:0032182 ubiquitin-like protein binding 18/1725 120/18639 0.15 1.62078260869565 0.0274871940116802 0.349965820664175 GO:0043022 ribosome binding 17/1725 112/18639 0.151785714285714 1.64007763975155 0.0284739596679693 0.352194671793504 GO:0070412 R-SMAD binding 6/1725 26/18639 0.230769230769231 2.49351170568562 0.0285112132157366 0.352194671793504 GO:0046332 SMAD binding 13/1725 79/18639 0.164556962025316 1.77807374793616 0.0287522050204916 0.352194671793504 GO:0071889 14-3-3 protein binding 7/1725 33/18639 0.212121212121212 2.29201581027668 0.028802965061655 0.352194671793504 GO:0140030 modification-dependent protein binding 24/1725 173/18639 0.138728323699422 1.49898969590349 0.0292737931766863 0.35444249581576 GO:0031267 small GTPase binding 36/1725 283/18639 0.127208480565371 1.37451528652635 0.031311332433432 0.36022788459192 GO:0005518 collagen binding 12/1725 72/18639 0.166666666666667 1.80086956521739 0.0318279865546489 0.36022788459192 GO:0031625 ubiquitin protein ligase binding 38/1725 302/18639 0.125827814569536 1.35959689029657 0.0319779937331603 0.36022788459192 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 5/1725 20/18639 0.25 2.70130434782609 0.0322191844840966 0.36022788459192 GO:0031418 L-ascorbic acid binding 5/1725 20/18639 0.25 2.70130434782609 0.0322191844840966 0.36022788459192 GO:0035091 phosphatidylinositol binding 36/1725 284/18639 0.126760563380282 1.36967544396816 0.0327777602884483 0.36022788459192 GO:0008175 tRNA methyltransferase activity 7/1725 34/18639 0.205882352941176 2.22460358056266 0.0334689637238035 0.36022788459192 GO:0003727 single-stranded RNA binding 14/1725 89/18639 0.157303370786517 1.69969711773327 0.033750178772752 0.36022788459192 GO:0008266 poly(U) RNA binding 6/1725 27/18639 0.222222222222222 2.40115942028986 0.0338765676191909 0.36022788459192 GO:0044389 ubiquitin-like protein ligase binding 40/1725 322/18639 0.124223602484472 1.3422630299757 0.0339078150153165 0.36022788459192 GO:0004065 arylsulfatase activity 4/1725 14/18639 0.285714285714286 3.0872049689441 0.0343980809365682 0.36022788459192 GO:0008331 high voltage-gated calcium channel activity 4/1725 14/18639 0.285714285714286 3.0872049689441 0.0343980809365682 0.36022788459192 GO:0008559 ABC-type xenobiotic transporter activity 4/1725 14/18639 0.285714285714286 3.0872049689441 0.0343980809365682 0.36022788459192 GO:0015926 glucosidase activity 4/1725 14/18639 0.285714285714286 3.0872049689441 0.0343980809365682 0.36022788459192 GO:0098821 BMP receptor activity 4/1725 14/18639 0.285714285714286 3.0872049689441 0.0343980809365682 0.36022788459192 GO:0015101 organic cation transmembrane transporter activity 13/1725 81/18639 0.160493827160494 1.73417069243156 0.0344939961651341 0.36022788459192 GO:0016504 peptidase activator activity 10/1725 57/18639 0.175438596491228 1.89565217391304 0.0348773009771834 0.36022788459192 GO:0004521 RNA endonuclease activity 12/1725 73/18639 0.164383561643836 1.77620011911852 0.0350018997174336 0.36022788459192 GO:0042578 phosphoric ester hydrolase activity 44/1725 363/18639 0.121212121212121 1.3097233201581 0.0388204162119413 0.396224909270641 GO:0004089 carbonate dehydratase activity 4/1725 15/18639 0.266666666666667 2.88139130434783 0.0435634781921022 0.44099094727251 GO:0140035 ubiquitin-like protein reader activity 5/1725 22/18639 0.227272727272727 2.45573122529644 0.0469482335083955 0.471390799860719 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 9/1725 52/18639 0.173076923076923 1.87013377926421 0.0474589319042968 0.472675652433924 GO:1902936 phosphatidylinositol bisphosphate binding 16/1725 111/18639 0.144144144144144 1.55750881316099 0.0494622804125381 0.487578221327726 GO:0019213 deacetylase activity 7/1725 37/18639 0.189189189189189 2.0442303172738 0.0503810348824127 0.487578221327726 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 13/1725 86/18639 0.151162790697674 1.63334681496461 0.052346144165642 0.487578221327726 GO:0050660 flavin adenine dinucleotide binding 13/1725 86/18639 0.151162790697674 1.63334681496461 0.052346144165642 0.487578221327726 GO:0004679 AMP-activated protein kinase activity 31/1725 248/18639 0.125 1.35065217391304 0.0524617244287147 0.487578221327726 GO:0140296 general transcription initiation factor binding 9/1725 53/18639 0.169811320754717 1.83484823625923 0.0526687090324875 0.487578221327726 GO:0008187 poly-pyrimidine tract binding 6/1725 30/18639 0.2 2.16104347826087 0.0536995018518653 0.487578221327726 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 4/1725 16/18639 0.25 2.70130434782609 0.0539615337796702 0.487578221327726 GO:0016798 hydrolase activity, acting on glycosyl bonds 18/1725 130/18639 0.138461538461538 1.49610702341137 0.0543515346809808 0.487578221327726 GO:0099186 structural constituent of postsynapse 5/1725 23/18639 0.217391304347826 2.34896030245747 0.0555844066271183 0.487578221327726 GO:0008081 phosphoric diester hydrolase activity 13/1725 87/18639 0.149425287356322 1.61457271364318 0.0565562841109228 0.487578221327726 GO:0000182 rDNA binding 3/1725 10/18639 0.3 3.2415652173913 0.0579013018695683 0.487578221327726 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 3/1725 10/18639 0.3 3.2415652173913 0.0579013018695683 0.487578221327726 GO:0004862 cAMP-dependent protein kinase inhibitor activity 3/1725 10/18639 0.3 3.2415652173913 0.0579013018695683 0.487578221327726 GO:0005381 iron ion transmembrane transporter activity 3/1725 10/18639 0.3 3.2415652173913 0.0579013018695683 0.487578221327726 GO:0008140 cAMP response element binding protein binding 3/1725 10/18639 0.3 3.2415652173913 0.0579013018695683 0.487578221327726 GO:0016868 intramolecular phosphotransferase activity 3/1725 10/18639 0.3 3.2415652173913 0.0579013018695683 0.487578221327726 GO:0035256 G protein-coupled glutamate receptor binding 3/1725 10/18639 0.3 3.2415652173913 0.0579013018695683 0.487578221327726 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 3/1725 10/18639 0.3 3.2415652173913 0.0579013018695683 0.487578221327726 GO:1905394 retromer complex binding 3/1725 10/18639 0.3 3.2415652173913 0.0579013018695683 0.487578221327726 GO:0016651 oxidoreductase activity, acting on NAD(P)H 13/1725 88/18639 0.147727272727273 1.59622529644269 0.0609893672150137 0.487578221327726 GO:1901682 sulfur compound transmembrane transporter activity 10/1725 63/18639 0.158730158730159 1.71511387163561 0.0627975552721469 0.487578221327726 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 30/1725 243/18639 0.123456790123457 1.33397745571659 0.0634570574165164 0.487578221327726 GO:0140359 ABC-type transporter activity 8/1725 47/18639 0.170212765957447 1.83918593894542 0.0647927764071728 0.487578221327726 GO:0050431 transforming growth factor beta binding 5/1725 24/18639 0.208333333333333 2.25108695652174 0.0650728092556455 0.487578221327726 GO:0008484 sulfuric ester hydrolase activity 4/1725 17/18639 0.235294117647059 2.54240409207161 0.0655764804281784 0.487578221327726 GO:0032183 SUMO binding 4/1725 17/18639 0.235294117647059 2.54240409207161 0.0655764804281784 0.487578221327726 GO:0051787 misfolded protein binding 4/1725 17/18639 0.235294117647059 2.54240409207161 0.0655764804281784 0.487578221327726 GO:0005525 GTP binding 44/1725 378/18639 0.116402116402116 1.25775017253278 0.0667969063798158 0.487578221327726 GO:0004676 3-phosphoinositide-dependent protein kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0004711 ribosomal protein S6 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0035175 histone H3S10 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0035979 histone H2AXS139 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0044022 histone H3S28 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0044023 histone H4S1 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0044024 histone H2AS1 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0044025 histone H2BS14 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0072354 histone H3T3 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0072371 histone H2AS121 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0072518 Rho-dependent protein serine/threonine kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0140823 histone H2BS36 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0140855 histone H3S57 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0140995 histone H2A kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0140997 histone H4 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0140998 histone H2B kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:1990244 histone H2AT120 kinase activity 30/1725 245/18639 0.122448979591837 1.32308784383319 0.069068499931383 0.487578221327726 GO:0030515 snoRNA binding 6/1725 32/18639 0.1875 2.02597826086957 0.0701240365076027 0.487578221327726 GO:0016853 isomerase activity 23/1725 180/18639 0.127777777777778 1.38066666666667 0.0702931104584118 0.487578221327726 GO:0009378 four-way junction helicase activity 8/1725 48/18639 0.166666666666667 1.80086956521739 0.0717378149725346 0.487578221327726 GO:0043138 3'-5' DNA helicase activity 8/1725 48/18639 0.166666666666667 1.80086956521739 0.0717378149725346 0.487578221327726 GO:0061791 GTPase motor activity 7/1725 40/18639 0.175 1.89091304347826 0.0718775518547659 0.487578221327726 GO:1990606 membrane scission GTPase motor activity 7/1725 40/18639 0.175 1.89091304347826 0.0718775518547659 0.487578221327726 GO:0004677 DNA-dependent protein kinase activity 30/1725 246/18639 0.121951219512195 1.31770943796394 0.0720007888529919 0.487578221327726 GO:0140857 histone H3T45 kinase activity 30/1725 246/18639 0.121951219512195 1.31770943796394 0.0720007888529919 0.487578221327726 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 3/1725 11/18639 0.272727272727273 2.94687747035573 0.0742962020339578 0.487578221327726 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 3/1725 11/18639 0.272727272727273 2.94687747035573 0.0742962020339578 0.487578221327726 GO:0003953 NAD+ nucleosidase activity 3/1725 11/18639 0.272727272727273 2.94687747035573 0.0742962020339578 0.487578221327726 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 3/1725 11/18639 0.272727272727273 2.94687747035573 0.0742962020339578 0.487578221327726 GO:0015173 aromatic amino acid transmembrane transporter activity 3/1725 11/18639 0.272727272727273 2.94687747035573 0.0742962020339578 0.487578221327726 GO:0035252 UDP-xylosyltransferase activity 3/1725 11/18639 0.272727272727273 2.94687747035573 0.0742962020339578 0.487578221327726 GO:0042285 xylosyltransferase activity 3/1725 11/18639 0.272727272727273 2.94687747035573 0.0742962020339578 0.487578221327726 GO:0043522 leucine zipper domain binding 3/1725 11/18639 0.272727272727273 2.94687747035573 0.0742962020339578 0.487578221327726 GO:0097493 structural molecule activity conferring elasticity 3/1725 11/18639 0.272727272727273 2.94687747035573 0.0742962020339578 0.487578221327726 GO:0035402 histone H3T11 kinase activity 30/1725 247/18639 0.121457489878543 1.3123745819398 0.0750186136219324 0.487578221327726 GO:0035403 histone H3T6 kinase activity 30/1725 247/18639 0.121457489878543 1.3123745819398 0.0750186136219324 0.487578221327726 GO:0000030 mannosyltransferase activity 5/1725 25/18639 0.2 2.16104347826087 0.0754068342296322 0.487578221327726 GO:0017056 structural constituent of nuclear pore 5/1725 25/18639 0.2 2.16104347826087 0.0754068342296322 0.487578221327726 GO:0044325 transmembrane transporter binding 18/1725 136/18639 0.132352941176471 1.43010230179028 0.0772883315822573 0.488866013860266 GO:0051020 GTPase binding 37/1725 315/18639 0.117460317460317 1.26918426501035 0.0782391897007691 0.488866013860266 GO:0000400 four-way junction DNA binding 4/1725 18/18639 0.222222222222222 2.40115942028986 0.0783768993881237 0.488866013860266 GO:0004706 JUN kinase kinase kinase activity 4/1725 18/18639 0.222222222222222 2.40115942028986 0.0783768993881237 0.488866013860266 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 4/1725 18/18639 0.222222222222222 2.40115942028986 0.0783768993881237 0.488866013860266 GO:0030228 lipoprotein particle receptor activity 4/1725 18/18639 0.222222222222222 2.40115942028986 0.0783768993881237 0.488866013860266 GO:0031690 adrenergic receptor binding 4/1725 18/18639 0.222222222222222 2.40115942028986 0.0783768993881237 0.488866013860266 GO:0035254 glutamate receptor binding 8/1725 49/18639 0.163265306122449 1.76411712511091 0.079117661601827 0.489619803023892 GO:0030165 PDZ domain binding 12/1725 83/18639 0.144578313253012 1.56220010476689 0.079636746853762 0.489619803023892 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 7/1725 41/18639 0.170731707317073 1.84479321314952 0.080083562923746 0.489619803023892 GO:0015175 neutral L-amino acid transmembrane transporter activity 7/1725 41/18639 0.170731707317073 1.84479321314952 0.080083562923746 0.489619803023892 GO:0004222 metalloendopeptidase activity 15/1725 110/18639 0.136363636363636 1.47343873517787 0.0822421429492114 0.500340130750128 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 9/1725 58/18639 0.155172413793103 1.67667166416792 0.0841978933262345 0.509727442440684 GO:0004435 phosphatidylinositol phospholipase C activity 5/1725 26/18639 0.192307692307692 2.07792642140468 0.0865724582805598 0.516811463241069 GO:0005227 calcium-activated cation channel activity 5/1725 26/18639 0.192307692307692 2.07792642140468 0.0865724582805598 0.516811463241069 GO:0004520 DNA endonuclease activity 7/1725 42/18639 0.166666666666667 1.80086956521739 0.0888083353887113 0.516811463241069 GO:0015078 proton transmembrane transporter activity 23/1725 185/18639 0.124324324324324 1.34335135135135 0.0889775390870013 0.516811463241069 GO:1901981 phosphatidylinositol phosphate binding 23/1725 185/18639 0.124324324324324 1.34335135135135 0.0889775390870013 0.516811463241069 GO:0016831 carboxy-lyase activity 6/1725 34/18639 0.176470588235294 1.90680306905371 0.0891288253514504 0.516811463241069 GO:0005096 GTPase activator activity 32/1725 271/18639 0.118081180811808 1.2758928284935 0.0907901690726237 0.516811463241069 GO:0001786 phosphatidylserine binding 9/1725 59/18639 0.152542372881356 1.64825350036846 0.091617930027648 0.516811463241069 GO:0004540 RNA nuclease activity 16/1725 121/18639 0.132231404958678 1.42878907653611 0.0923047761314041 0.516811463241069 GO:0005520 insulin-like growth factor binding 4/1725 19/18639 0.210526315789474 2.27478260869565 0.0923177455568412 0.516811463241069 GO:0022804 active transmembrane transporter activity 51/1725 457/18639 0.111597374179431 1.20583388830749 0.0923653166546417 0.516811463241069 GO:0000995 RNA polymerase III general transcription initiation factor activity 3/1725 12/18639 0.25 2.70130434782609 0.0924820513168228 0.516811463241069 GO:0008603 cAMP-dependent protein kinase regulator activity 3/1725 12/18639 0.25 2.70130434782609 0.0924820513168228 0.516811463241069 GO:0015166 polyol transmembrane transporter activity 3/1725 12/18639 0.25 2.70130434782609 0.0924820513168228 0.516811463241069 GO:0016423 tRNA (guanine) methyltransferase activity 3/1725 12/18639 0.25 2.70130434782609 0.0924820513168228 0.516811463241069 GO:0017166 vinculin binding 3/1725 12/18639 0.25 2.70130434782609 0.0924820513168228 0.516811463241069 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/1725 12/18639 0.25 2.70130434782609 0.0924820513168228 0.516811463241069 GO:0005245 voltage-gated calcium channel activity 7/1725 43/18639 0.162790697674419 1.7589888776542 0.0980469047014413 0.545441113992252 GO:0000339 RNA cap binding 4/1725 20/18639 0.2 2.16104347826087 0.107342385825027 0.587819533988309 GO:0052745 inositol phosphate phosphatase activity 4/1725 20/18639 0.2 2.16104347826087 0.107342385825027 0.587819533988309 GO:0015026 coreceptor activity 9/1725 61/18639 0.147540983606557 1.59421240199572 0.107568594883691 0.587819533988309 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 9/1725 61/18639 0.147540983606557 1.59421240199572 0.107568594883691 0.587819533988309 GO:0016866 intramolecular transferase activity 5/1725 28/18639 0.178571428571429 1.92950310559006 0.111308719368839 0.595172524242432 GO:0051393 alpha-actinin binding 5/1725 28/18639 0.178571428571429 1.92950310559006 0.111308719368839 0.595172524242432 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 5/1725 28/18639 0.178571428571429 1.92950310559006 0.111308719368839 0.595172524242432 GO:0005172 vascular endothelial growth factor receptor binding 3/1725 13/18639 0.230769230769231 2.49351170568562 0.112287609836831 0.595172524242432 GO:0005338 nucleotide-sugar transmembrane transporter activity 3/1725 13/18639 0.230769230769231 2.49351170568562 0.112287609836831 0.595172524242432 GO:0043560 insulin receptor substrate binding 3/1725 13/18639 0.230769230769231 2.49351170568562 0.112287609836831 0.595172524242432 GO:0061459 L-arginine transmembrane transporter activity 3/1725 13/18639 0.230769230769231 2.49351170568562 0.112287609836831 0.595172524242432 GO:0051018 protein kinase A binding 8/1725 53/18639 0.150943396226415 1.6309762100082 0.112956210852025 0.596157779496799 GO:0015179 L-amino acid transmembrane transporter activity 9/1725 62/18639 0.145161290322581 1.56849929873773 0.116092277628262 0.607688356018994 GO:0019903 protein phosphatase binding 18/1725 144/18639 0.125 1.35065217391304 0.116682680310529 0.607688356018994 GO:0019888 protein phosphatase regulator activity 14/1725 107/18639 0.130841121495327 1.41376676147907 0.117160879636749 0.607688356018994 GO:0000287 magnesium ion binding 27/1725 230/18639 0.117391304347826 1.26843856332703 0.118287050379208 0.607688356018994 GO:0000049 tRNA binding 11/1725 80/18639 0.1375 1.48571739130435 0.118567311979271 0.607688356018994 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 12/1725 89/18639 0.134831460674157 1.45688324377137 0.118585339109779 0.607688356018994 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 12/1725 89/18639 0.134831460674157 1.45688324377137 0.118585339109779 0.607688356018994 GO:0005543 phospholipid binding 54/1725 497/18639 0.108651911468813 1.17400752340128 0.120865941219306 0.616815857048935 GO:0019208 phosphatase regulator activity 15/1725 117/18639 0.128205128205128 1.38528428093645 0.122265354833114 0.619080655601361 GO:0042805 actinin binding 6/1725 37/18639 0.162162162162162 1.75219741480611 0.122312291471038 0.619080655601361 GO:0015174 basic amino acid transmembrane transporter activity 4/1725 21/18639 0.19047619047619 2.05813664596273 0.123384592631598 0.619430780081397 GO:0070182 DNA polymerase binding 4/1725 21/18639 0.19047619047619 2.05813664596273 0.123384592631598 0.619430780081397 GO:0030246 carbohydrate binding 32/1725 280/18639 0.114285714285714 1.23488198757764 0.124387687002208 0.621580982425568 GO:0004629 phospholipase C activity 5/1725 29/18639 0.172413793103448 1.86296851574213 0.124819500924325 0.621580982425568 GO:0140793 histone H2AXY142 phosphatase activity 12/1725 90/18639 0.133333333333333 1.44069565217391 0.12597737027435 0.624827519232218 GO:0008237 metallopeptidase activity 22/1725 184/18639 0.119565217391304 1.29192816635161 0.128074359084081 0.631093432008175 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 7/1725 46/18639 0.152173913043478 1.64427221172023 0.128757384936244 0.631093432008175 GO:0022853 active monoatomic ion transmembrane transporter activity 15/1725 118/18639 0.127118644067797 1.37354458364038 0.12877372053932 0.631093432008175 GO:0019001 guanyl nucleotide binding 44/1725 400/18639 0.11 1.18857391304348 0.130221971736708 0.633165886200136 GO:0032561 guanyl ribonucleotide binding 44/1725 400/18639 0.11 1.18857391304348 0.130221971736708 0.633165886200136 GO:0043130 ubiquitin binding 13/1725 100/18639 0.13 1.40467826086957 0.132293894032077 0.634268490982108 GO:0008191 metalloendopeptidase inhibitor activity 3/1725 14/18639 0.214285714285714 2.31540372670807 0.133530208627812 0.634268490982108 GO:0008195 phosphatidate phosphatase activity 3/1725 14/18639 0.214285714285714 2.31540372670807 0.133530208627812 0.634268490982108 GO:0070742 C2H2 zinc finger domain binding 3/1725 14/18639 0.214285714285714 2.31540372670807 0.133530208627812 0.634268490982108 GO:0098847 sequence-specific single stranded DNA binding 3/1725 14/18639 0.214285714285714 2.31540372670807 0.133530208627812 0.634268490982108 GO:1901474 azole transmembrane transporter activity 3/1725 14/18639 0.214285714285714 2.31540372670807 0.133530208627812 0.634268490982108 GO:0004536 DNA nuclease activity 9/1725 64/18639 0.140625 1.51948369565217 0.134209290804113 0.635051625069268 GO:0016791 phosphatase activity 31/1725 273/18639 0.113553113553114 1.22696607740086 0.136304950900022 0.642506161685218 GO:0022839 monoatomic ion-gated channel activity 5/1725 30/18639 0.166666666666667 1.80086956521739 0.139043500738816 0.646856365727415 GO:0098918 structural constituent of synapse 5/1725 30/18639 0.166666666666667 1.80086956521739 0.139043500738816 0.646856365727415 GO:0035591 signaling adaptor activity 16/1725 129/18639 0.124031007751938 1.34018200202224 0.139667139246503 0.646856365727415 GO:0061749 forked DNA-dependent helicase activity 7/1725 47/18639 0.148936170212766 1.60928769657724 0.139951191428832 0.646856365727415 GO:1990518 single-stranded 3'-5' DNA helicase activity 7/1725 47/18639 0.148936170212766 1.60928769657724 0.139951191428832 0.646856365727415 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 4/1725 22/18639 0.181818181818182 1.96458498023715 0.140370450214532 0.646856365727415 GO:0043178 alcohol binding 12/1725 92/18639 0.130434782608696 1.40937618147448 0.141512564453236 0.647288952221284 GO:0052689 carboxylic ester hydrolase activity 12/1725 92/18639 0.130434782608696 1.40937618147448 0.141512564453236 0.647288952221284 GO:0003684 damaged DNA binding 10/1725 74/18639 0.135135135135135 1.46016451233843 0.143729177767779 0.652593876997085 GO:0035064 methylated histone binding 10/1725 74/18639 0.135135135135135 1.46016451233843 0.143729177767779 0.652593876997085 GO:0003697 single-stranded DNA binding 15/1725 121/18639 0.12396694214876 1.33948975925261 0.149456319562085 0.676111921828481 GO:0036121 double-stranded DNA helicase activity 7/1725 48/18639 0.145833333333333 1.57576086956522 0.151597377653077 0.680810041460184 GO:0140693 molecular condensate scaffold activity 7/1725 48/18639 0.145833333333333 1.57576086956522 0.151597377653077 0.680810041460184 GO:0015932 nucleobase-containing compound transmembrane transporter activity 8/1725 57/18639 0.140350877192982 1.51652173913043 0.153420325168543 0.686500368054894 GO:0004559 alpha-mannosidase activity 3/1725 15/18639 0.2 2.16104347826087 0.15602189123674 0.693118833371847 GO:0005041 low-density lipoprotein particle receptor activity 3/1725 15/18639 0.2 2.16104347826087 0.15602189123674 0.693118833371847 GO:0003887 DNA-directed DNA polymerase activity 4/1725 23/18639 0.173913043478261 1.87916824196597 0.158220143601356 0.697863847670267 GO:0005158 insulin receptor binding 4/1725 23/18639 0.173913043478261 1.87916824196597 0.158220143601356 0.697863847670267 GO:0004177 aminopeptidase activity 6/1725 40/18639 0.15 1.62078260869565 0.160663822868124 0.703616387383449 GO:0071949 FAD binding 6/1725 40/18639 0.15 1.62078260869565 0.160663822868124 0.703616387383449 GO:0140034 methylation-dependent protein binding 10/1725 76/18639 0.131578947368421 1.42173913043478 0.162495299413411 0.707928265590742 GO:0008173 RNA methyltransferase activity 9/1725 67/18639 0.134328358208955 1.45144711226476 0.163941282557856 0.707928265590742 GO:0042054 histone methyltransferase activity 9/1725 67/18639 0.134328358208955 1.45144711226476 0.163941282557856 0.707928265590742 GO:0050840 extracellular matrix binding 9/1725 67/18639 0.134328358208955 1.45144711226476 0.163941282557856 0.707928265590742 GO:0070717 poly-purine tract binding 5/1725 32/18639 0.15625 1.6883152173913 0.16946010580925 0.729209862977087 GO:0008201 heparin binding 20/1725 172/18639 0.116279069767442 1.25642062689585 0.17058347988575 0.731495130760074 GO:0106310 protein serine kinase activity 39/1725 361/18639 0.10803324099723 1.16732265446224 0.174318608896934 0.74003683761865 GO:0032934 sterol binding 9/1725 68/18639 0.132352941176471 1.43010230179028 0.174494455000138 0.74003683761865 GO:1990841 promoter-specific chromatin binding 9/1725 68/18639 0.132352941176471 1.43010230179028 0.174494455000138 0.74003683761865 GO:0015459 potassium channel regulator activity 8/1725 59/18639 0.135593220338983 1.46511422254974 0.17592775492773 0.74003683761865 GO:0070063 RNA polymerase binding 8/1725 59/18639 0.135593220338983 1.46511422254974 0.17592775492773 0.74003683761865 GO:0015605 organophosphate ester transmembrane transporter activity 7/1725 50/18639 0.14 1.51273043478261 0.176170712761039 0.74003683761865 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 3/1725 16/18639 0.1875 2.02597826086957 0.17957428141914 0.746714604554338 GO:0015923 mannosidase activity 3/1725 16/18639 0.1875 2.02597826086957 0.17957428141914 0.746714604554338 GO:0030275 LRR domain binding 3/1725 16/18639 0.1875 2.02597826086957 0.17957428141914 0.746714604554338 GO:0003712 transcription coregulator activity 52/1725 495/18639 0.105050505050505 1.13509354413702 0.184415065254875 0.763884404087783 GO:0002039 p53 binding 9/1725 69/18639 0.130434782608696 1.40937618147448 0.185349563379688 0.763884404087783 GO:0140416 transcription regulator inhibitor activity 5/1725 33/18639 0.151515151515152 1.63715415019763 0.185558964555737 0.763884404087783 GO:0001098 basal transcription machinery binding 8/1725 60/18639 0.133333333333333 1.44069565217391 0.187699855426944 0.765047265519064 GO:0001099 basal RNA polymerase II transcription machinery binding 8/1725 60/18639 0.133333333333333 1.44069565217391 0.187699855426944 0.765047265519064 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 8/1725 60/18639 0.133333333333333 1.44069565217391 0.187699855426944 0.765047265519064 GO:0016830 carbon-carbon lyase activity 7/1725 51/18639 0.137254901960784 1.48306905370844 0.18905564562841 0.768038560365416 GO:0022832 voltage-gated channel activity 20/1725 175/18639 0.114285714285714 1.23488198757764 0.19062538406594 0.771876555152249 GO:0004725 protein tyrosine phosphatase activity 12/1725 98/18639 0.122448979591837 1.32308784383319 0.193797784082719 0.775209050199659 GO:0042626 ATPase-coupled transmembrane transporter activity 12/1725 98/18639 0.122448979591837 1.32308784383319 0.193797784082719 0.775209050199659 GO:1901681 sulfur compound binding 30/1725 275/18639 0.109090909090909 1.17875098814229 0.195692158695604 0.775209050199659 GO:0004709 MAP kinase kinase kinase activity 4/1725 25/18639 0.16 1.7288347826087 0.196172044040187 0.775209050199659 GO:0017025 TBP-class protein binding 4/1725 25/18639 0.16 1.7288347826087 0.196172044040187 0.775209050199659 GO:0016836 hydro-lyase activity 8/1725 61/18639 0.131147540983607 1.41707769066287 0.199795140037247 0.775209050199659 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 5/1725 34/18639 0.147058823529412 1.58900255754476 0.202184850625441 0.775209050199659 GO:0052866 phosphatidylinositol phosphate phosphatase activity 5/1725 34/18639 0.147058823529412 1.58900255754476 0.202184850625441 0.775209050199659 GO:0005080 protein kinase C binding 7/1725 52/18639 0.134615384615385 1.45454849498328 0.202308891080793 0.775209050199659 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1725 43/18639 0.13953488372093 1.50770475227503 0.203465338312922 0.775209050199659 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0004549 tRNA-specific ribonuclease activity 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0004659 prenyltransferase activity 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0015278 intracellularly gated calcium channel activity 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0019198 transmembrane receptor protein phosphatase activity 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0030169 low-density lipoprotein particle binding 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0038191 neuropilin binding 3/1725 17/18639 0.176470588235294 1.90680306905371 0.204002381631489 0.775209050199659 GO:0042393 histone binding 27/1725 247/18639 0.109311740890688 1.18113712374582 0.207417619427464 0.785769202432262 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 37/1725 349/18639 0.106017191977077 1.14553880652797 0.213904010595869 0.792472702166758 GO:0004864 protein phosphatase inhibitor activity 7/1725 53/18639 0.132075471698113 1.42710418375718 0.215906038072127 0.792472702166758 GO:0017046 peptide hormone binding 7/1725 53/18639 0.132075471698113 1.42710418375718 0.215906038072127 0.792472702166758 GO:1901505 carbohydrate derivative transmembrane transporter activity 7/1725 53/18639 0.132075471698113 1.42710418375718 0.215906038072127 0.792472702166758 GO:0004112 cyclic-nucleotide phosphodiesterase activity 4/1725 26/18639 0.153846153846154 1.66234113712375 0.216099241451028 0.792472702166758 GO:0005160 transforming growth factor beta receptor binding 4/1725 26/18639 0.153846153846154 1.66234113712375 0.216099241451028 0.792472702166758 GO:0008157 protein phosphatase 1 binding 4/1725 26/18639 0.153846153846154 1.66234113712375 0.216099241451028 0.792472702166758 GO:0008198 ferrous iron binding 4/1725 26/18639 0.153846153846154 1.66234113712375 0.216099241451028 0.792472702166758 GO:0043548 phosphatidylinositol 3-kinase binding 4/1725 26/18639 0.153846153846154 1.66234113712375 0.216099241451028 0.792472702166758 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 11/1725 91/18639 0.120879120879121 1.30612517916866 0.219019678661688 0.792472702166758 GO:0072341 modified amino acid binding 11/1725 91/18639 0.120879120879121 1.30612517916866 0.219019678661688 0.792472702166758 GO:0005343 organic acid:sodium symporter activity 5/1725 35/18639 0.142857142857143 1.54360248447205 0.219285549243656 0.792472702166758 GO:0034061 DNA polymerase activity 5/1725 35/18639 0.142857142857143 1.54360248447205 0.219285549243656 0.792472702166758 GO:0140566 histone reader activity 5/1725 35/18639 0.142857142857143 1.54360248447205 0.219285549243656 0.792472702166758 GO:0016829 lyase activity 22/1725 200/18639 0.11 1.18857391304348 0.226946804401854 0.792472702166758 GO:0008308 voltage-gated monoatomic anion channel activity 3/1725 18/18639 0.166666666666667 1.80086956521739 0.229127478080162 0.792472702166758 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 3/1725 18/18639 0.166666666666667 1.80086956521739 0.229127478080162 0.792472702166758 GO:0015485 cholesterol binding 7/1725 54/18639 0.12962962962963 1.40067632850242 0.229821687003536 0.792472702166758 GO:0140463 chromatin-protein adaptor activity 7/1725 54/18639 0.12962962962963 1.40067632850242 0.229821687003536 0.792472702166758 GO:0015171 amino acid transmembrane transporter activity 12/1725 102/18639 0.117647058823529 1.27120204603581 0.232882352691951 0.792472702166758 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0005528 FK506 binding 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0015187 glycine transmembrane transporter activity 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0015279 store-operated calcium channel activity 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0030957 Tat protein binding 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0033204 ribonuclease P RNA binding 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0043121 neurotrophin binding 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0043295 glutathione binding 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0045322 unmethylated CpG binding 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0140135 mechanosensitive monoatomic cation channel activity 2/1725 10/18639 0.2 2.16104347826087 0.23516223928246 0.792472702166758 GO:0001540 amyloid-beta binding 10/1725 83/18639 0.120481927710843 1.30183342063908 0.23649864531883 0.792472702166758 GO:0008135 translation factor activity, RNA binding 10/1725 83/18639 0.120481927710843 1.30183342063908 0.23649864531883 0.792472702166758 GO:0004364 glutathione transferase activity 4/1725 27/18639 0.148148148148148 1.6007729468599 0.236542796996036 0.792472702166758 GO:0005044 scavenger receptor activity 4/1725 27/18639 0.148148148148148 1.6007729468599 0.236542796996036 0.792472702166758 GO:0008395 steroid hydroxylase activity 4/1725 27/18639 0.148148148148148 1.6007729468599 0.236542796996036 0.792472702166758 GO:0035255 ionotropic glutamate receptor binding 4/1725 27/18639 0.148148148148148 1.6007729468599 0.236542796996036 0.792472702166758 GO:0000993 RNA polymerase II complex binding 5/1725 36/18639 0.138888888888889 1.50072463768116 0.236807772770765 0.792472702166758 GO:0055106 ubiquitin-protein transferase regulator activity 5/1725 36/18639 0.138888888888889 1.50072463768116 0.236807772770765 0.792472702166758 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 14/1725 122/18639 0.114754098360656 1.23994297933001 0.237420971499353 0.792472702166758 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 15/1725 132/18639 0.113636363636364 1.22786561264822 0.238902857850069 0.795269621145109 GO:0140297 DNA-binding transcription factor binding 50/1725 488/18639 0.102459016393443 1.10709194583036 0.242823299503719 0.806147244320141 GO:0180051 translation factor activity 10/1725 84/18639 0.119047619047619 1.28633540372671 0.247978969473329 0.820590243268713 GO:0022843 voltage-gated monoatomic cation channel activity 16/1725 143/18639 0.111888111888112 1.20897537245363 0.248731240760099 0.820590243268713 GO:0005244 voltage-gated monoatomic ion channel activity 19/1725 173/18639 0.109826589595376 1.1867001759236 0.249456725655458 0.820590243268713 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1725 46/18639 0.130434782608696 1.40937618147448 0.249831523456709 0.820590243268713 GO:0160215 deacylase activity 8/1725 65/18639 0.123076923076923 1.329872909699 0.251035145242614 0.820597512247674 GO:0042562 hormone binding 11/1725 94/18639 0.117021276595745 1.26444033302498 0.251162639376211 0.820597512247674 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/1725 19/18639 0.157894736842105 1.70608695652174 0.254779302928285 0.825859420253103 GO:0031420 alkali metal ion binding 3/1725 19/18639 0.157894736842105 1.70608695652174 0.254779302928285 0.825859420253103 GO:0042577 lipid phosphatase activity 3/1725 19/18639 0.157894736842105 1.70608695652174 0.254779302928285 0.825859420253103 GO:0003714 transcription corepressor activity 22/1725 204/18639 0.107843137254902 1.16526854219949 0.255992547213786 0.82761988431682 GO:0050698 proteoglycan sulfotransferase activity 4/1725 28/18639 0.142857142857143 1.54360248447205 0.257415143267235 0.83004621915153 GO:0019212 phosphatase inhibitor activity 7/1725 56/18639 0.125 1.35065217391304 0.258503038931489 0.831383471563512 GO:0017124 SH3 domain binding 13/1725 115/18639 0.11304347826087 1.22145935727788 0.265280935367567 0.849172984102751 GO:0098631 cell adhesion mediator activity 9/1725 76/18639 0.118421052631579 1.2795652173913 0.268609255884683 0.849172984102751 GO:0000099 sulfur amino acid transmembrane transporter activity 2/1725 11/18639 0.181818181818182 1.96458498023715 0.270910247559906 0.849172984102751 GO:0005114 type II transforming growth factor beta receptor binding 2/1725 11/18639 0.181818181818182 1.96458498023715 0.270910247559906 0.849172984102751 GO:0008172 S-methyltransferase activity 2/1725 11/18639 0.181818181818182 1.96458498023715 0.270910247559906 0.849172984102751 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/1725 11/18639 0.181818181818182 1.96458498023715 0.270910247559906 0.849172984102751 GO:0034713 type I transforming growth factor beta receptor binding 2/1725 11/18639 0.181818181818182 1.96458498023715 0.270910247559906 0.849172984102751 GO:0048407 platelet-derived growth factor binding 2/1725 11/18639 0.181818181818182 1.96458498023715 0.270910247559906 0.849172984102751 GO:0050998 nitric-oxide synthase binding 2/1725 11/18639 0.181818181818182 1.96458498023715 0.270910247559906 0.849172984102751 GO:1900750 oligopeptide binding 2/1725 11/18639 0.181818181818182 1.96458498023715 0.270910247559906 0.849172984102751 GO:0042162 telomeric DNA binding 5/1725 38/18639 0.131578947368421 1.42173913043478 0.272901422888856 0.850183041009948 GO:0043531 ADP binding 5/1725 38/18639 0.131578947368421 1.42173913043478 0.272901422888856 0.850183041009948 GO:0033218 amide binding 26/1725 247/18639 0.105263157894737 1.13739130434783 0.273297706300364 0.850183041009948 GO:0005416 amino acid:monoatomic cation symporter activity 4/1725 29/18639 0.137931034482759 1.4903748125937 0.278630446042101 0.860508720310453 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/1725 29/18639 0.137931034482759 1.4903748125937 0.278630446042101 0.860508720310453 GO:0016758 hexosyltransferase activity 21/1725 197/18639 0.106598984771574 1.15182520414919 0.279942999171718 0.860508720310453 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 3/1725 20/18639 0.15 1.62078260869565 0.280797582417095 0.860508720310453 GO:0016505 peptidase activator activity involved in apoptotic process 3/1725 20/18639 0.15 1.62078260869565 0.280797582417095 0.860508720310453 GO:0140939 histone H4 methyltransferase activity 3/1725 20/18639 0.15 1.62078260869565 0.280797582417095 0.860508720310453 GO:0003924 GTPase activity 34/1725 331/18639 0.102719033232628 1.10990148430317 0.28568663435172 0.873324241149441 GO:0017116 single-stranded DNA helicase activity 7/1725 58/18639 0.120689655172414 1.30407796101949 0.28813679399879 0.878639359477791 GO:0005319 lipid transporter activity 19/1725 178/18639 0.106741573033708 1.153365901319 0.290636444347288 0.880600849139798 GO:0016776 phosphotransferase activity, phosphate group as acceptor 5/1725 39/18639 0.128205128205128 1.38528428093645 0.291365472987788 0.880600849139798 GO:0140223 general transcription initiation factor activity 8/1725 68/18639 0.117647058823529 1.27120204603581 0.291902852039522 0.880600849139798 GO:0004175 endopeptidase activity 41/1725 405/18639 0.101234567901235 1.0938615136876 0.29477931354124 0.880600849139798 GO:0001222 transcription corepressor binding 6/1725 49/18639 0.122448979591837 1.32308784383319 0.298786102535893 0.880600849139798 GO:0141003 histone H2AX kinase activity 36/1725 354/18639 0.101694915254237 1.09883566691231 0.299839958077641 0.880600849139798 GO:0001968 fibronectin binding 4/1725 30/18639 0.133333333333333 1.44069565217391 0.300105360704145 0.880600849139798 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 4/1725 30/18639 0.133333333333333 1.44069565217391 0.300105360704145 0.880600849139798 GO:0048019 receptor antagonist activity 4/1725 30/18639 0.133333333333333 1.44069565217391 0.300105360704145 0.880600849139798 GO:0051721 protein phosphatase 2A binding 4/1725 30/18639 0.133333333333333 1.44069565217391 0.300105360704145 0.880600849139798 GO:0070566 adenylyltransferase activity 4/1725 30/18639 0.133333333333333 1.44069565217391 0.300105360704145 0.880600849139798 GO:0019902 phosphatase binding 20/1725 190/18639 0.105263157894737 1.13739130434783 0.305862898446071 0.880600849139798 GO:0004032 aldose reductase (NADPH) activity 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0004526 ribonuclease P activity 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0005165 neurotrophin receptor binding 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0005247 voltage-gated chloride channel activity 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0005527 macrolide binding 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0008179 adenylate cyclase binding 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0015269 calcium-activated potassium channel activity 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0031543 peptidyl-proline dioxygenase activity 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0035251 UDP-glucosyltransferase activity 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0043047 single-stranded telomeric DNA binding 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/1725 12/18639 0.166666666666667 1.80086956521739 0.306595886808522 0.880600849139798 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 3/1725 21/18639 0.142857142857143 1.54360248447205 0.307033080714678 0.880600849139798 GO:0035613 RNA stem-loop binding 3/1725 21/18639 0.142857142857143 1.54360248447205 0.307033080714678 0.880600849139798 GO:0016835 carbon-oxygen lyase activity 9/1725 79/18639 0.113924050632911 1.23097413318657 0.307319000792917 0.880600849139798 GO:0030331 nuclear estrogen receptor binding 5/1725 40/18639 0.125 1.35065217391304 0.310037137290597 0.886333019800665 GO:0005539 glycosaminoglycan binding 25/1725 242/18639 0.103305785123967 1.11624146604384 0.311184439921984 0.887558391001501 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 19/1725 181/18639 0.104972375690608 1.13424933941869 0.316358487852619 0.900236710824849 GO:0140996 histone H3 kinase activity 36/1725 357/18639 0.100840336134454 1.08960175374498 0.318211567244321 0.902179173873905 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/1725 60/18639 0.116666666666667 1.26060869565217 0.318502121302852 0.902179173873905 GO:0019210 kinase inhibitor activity 10/1725 90/18639 0.111111111111111 1.20057971014493 0.320346827591442 0.905327991019292 GO:0072349 modified amino acid transmembrane transporter activity 4/1725 31/18639 0.129032258064516 1.39422159887798 0.321759659329816 0.907244701534983 GO:0005262 calcium channel activity 14/1725 131/18639 0.106870229007634 1.15475605708596 0.326482615570389 0.914048770989799 GO:0001727 lipid kinase activity 5/1725 41/18639 0.121951219512195 1.31770943796394 0.328864853342662 0.914048770989799 GO:0004812 aminoacyl-tRNA ligase activity 5/1725 41/18639 0.121951219512195 1.31770943796394 0.328864853342662 0.914048770989799 GO:0016875 ligase activity, forming carbon-oxygen bonds 5/1725 41/18639 0.121951219512195 1.31770943796394 0.328864853342662 0.914048770989799 GO:0140318 protein transporter activity 5/1725 41/18639 0.121951219512195 1.31770943796394 0.328864853342662 0.914048770989799 GO:0003743 translation initiation factor activity 6/1725 51/18639 0.117647058823529 1.27120204603581 0.332366481270581 0.914048770989799 GO:0005010 insulin-like growth factor receptor activity 6/1725 51/18639 0.117647058823529 1.27120204603581 0.332366481270581 0.914048770989799 GO:0005272 sodium channel activity 6/1725 51/18639 0.117647058823529 1.27120204603581 0.332366481270581 0.914048770989799 GO:0015377 chloride:monoatomic cation symporter activity 3/1725 22/18639 0.136363636363636 1.47343873517787 0.333348232898912 0.914048770989799 GO:0050321 tau-protein kinase activity 3/1725 22/18639 0.136363636363636 1.47343873517787 0.333348232898912 0.914048770989799 GO:0070034 telomerase RNA binding 3/1725 22/18639 0.136363636363636 1.47343873517787 0.333348232898912 0.914048770989799 GO:0140517 protein-RNA adaptor activity 3/1725 22/18639 0.136363636363636 1.47343873517787 0.333348232898912 0.914048770989799 GO:0030971 receptor tyrosine kinase binding 9/1725 81/18639 0.111111111111111 1.20057971014493 0.333794328515303 0.914048770989799 GO:0035173 histone kinase activity 36/1725 360/18639 0.1 1.08052173913043 0.336930786671737 0.916002083694312 GO:0003713 transcription coactivator activity 26/1725 256/18639 0.1015625 1.09740489130435 0.338458295096435 0.916002083694312 GO:0002161 aminoacyl-tRNA editing activity 2/1725 13/18639 0.153846153846154 1.66234113712375 0.341924664439739 0.916002083694312 GO:0009982 pseudouridine synthase activity 2/1725 13/18639 0.153846153846154 1.66234113712375 0.341924664439739 0.916002083694312 GO:0030955 potassium ion binding 2/1725 13/18639 0.153846153846154 1.66234113712375 0.341924664439739 0.916002083694312 GO:0031994 insulin-like growth factor I binding 2/1725 13/18639 0.153846153846154 1.66234113712375 0.341924664439739 0.916002083694312 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/1725 13/18639 0.153846153846154 1.66234113712375 0.341924664439739 0.916002083694312 GO:0046974 histone H3K9 methyltransferase activity 2/1725 13/18639 0.153846153846154 1.66234113712375 0.341924664439739 0.916002083694312 GO:0046975 histone H3K36 methyltransferase activity 2/1725 13/18639 0.153846153846154 1.66234113712375 0.341924664439739 0.916002083694312 GO:0051011 microtubule minus-end binding 2/1725 13/18639 0.153846153846154 1.66234113712375 0.341924664439739 0.916002083694312 GO:0051059 NF-kappaB binding 4/1725 32/18639 0.125 1.35065217391304 0.343516738404182 0.918275263915941 GO:0008307 structural constituent of muscle 5/1725 42/18639 0.119047619047619 1.28633540372671 0.347798510627224 0.919251444556014 GO:0042056 chemoattractant activity 5/1725 42/18639 0.119047619047619 1.28633540372671 0.347798510627224 0.919251444556014 GO:0043175 RNA polymerase core enzyme binding 5/1725 42/18639 0.119047619047619 1.28633540372671 0.347798510627224 0.919251444556014 GO:0005261 monoatomic cation channel activity 34/1725 341/18639 0.0997067448680352 1.07735305367844 0.349253833960195 0.919251444556014 GO:0004721 phosphoprotein phosphatase activity 18/1725 175/18639 0.102857142857143 1.11139378881988 0.354780567541039 0.919251444556014 GO:0051087 protein-folding chaperone binding 14/1725 134/18639 0.104477611940299 1.12890330953926 0.357855456892899 0.919251444556014 GO:0051219 phosphoprotein binding 10/1725 93/18639 0.10752688172043 1.16185133239832 0.358128989896648 0.919251444556014 GO:0004022 alcohol dehydrogenase (NAD+) activity 3/1725 23/18639 0.130434782608696 1.40937618147448 0.359617446293546 0.919251444556014 GO:0005212 structural constituent of eye lens 3/1725 23/18639 0.130434782608696 1.40937618147448 0.359617446293546 0.919251444556014 GO:0005283 amino acid:sodium symporter activity 3/1725 23/18639 0.130434782608696 1.40937618147448 0.359617446293546 0.919251444556014 GO:0008171 O-methyltransferase activity 3/1725 23/18639 0.130434782608696 1.40937618147448 0.359617446293546 0.919251444556014 GO:0016849 phosphorus-oxygen lyase activity 3/1725 23/18639 0.130434782608696 1.40937618147448 0.359617446293546 0.919251444556014 GO:0017134 fibroblast growth factor binding 3/1725 23/18639 0.130434782608696 1.40937618147448 0.359617446293546 0.919251444556014 GO:0042171 lysophosphatidic acid acyltransferase activity 3/1725 23/18639 0.130434782608696 1.40937618147448 0.359617446293546 0.919251444556014 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/1725 23/18639 0.130434782608696 1.40937618147448 0.359617446293546 0.919251444556014 GO:0071617 lysophospholipid acyltransferase activity 3/1725 23/18639 0.130434782608696 1.40937618147448 0.359617446293546 0.919251444556014 GO:0005267 potassium channel activity 13/1725 124/18639 0.104838709677419 1.13280504908836 0.36104810245066 0.919251444556014 GO:0043539 protein serine/threonine kinase activator activity 8/1725 73/18639 0.10958904109589 1.18413341274568 0.362956063694326 0.919251444556014 GO:0030296 protein tyrosine kinase activator activity 4/1725 33/18639 0.121212121212121 1.3097233201581 0.365304017555692 0.919251444556014 GO:0001216 DNA-binding transcription activator activity 48/1725 491/18639 0.0977596741344195 1.05631453112548 0.365794661049453 0.919251444556014 GO:0048156 tau protein binding 5/1725 43/18639 0.116279069767442 1.25642062689585 0.366789717510685 0.919251444556014 GO:0045296 cadherin binding 33/1725 334/18639 0.0988023952095808 1.06758135902109 0.372479532319839 0.919251444556014 GO:0004527 exonuclease activity 9/1725 84/18639 0.107142857142857 1.15770186335404 0.374160844655824 0.919251444556014 GO:0004860 protein kinase inhibitor activity 9/1725 84/18639 0.107142857142857 1.15770186335404 0.374160844655824 0.919251444556014 GO:0005347 ATP transmembrane transporter activity 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0005545 1-phosphatidylinositol binding 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0008174 mRNA methyltransferase activity 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0008494 translation activator activity 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0031404 chloride ion binding 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0034236 protein kinase A catalytic subunit binding 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0042043 neurexin family protein binding 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0042813 Wnt receptor activity 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0046030 inositol trisphosphate phosphatase activity 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0071933 Arp2/3 complex binding 2/1725 14/18639 0.142857142857143 1.54360248447205 0.376657073741727 0.919251444556014 GO:0016874 ligase activity 17/1725 167/18639 0.101796407185629 1.09993230929445 0.377144180539712 0.919251444556014 GO:0003678 DNA helicase activity 8/1725 74/18639 0.108108108108108 1.16813160987074 0.377414492325448 0.919251444556014 GO:0031491 nucleosome binding 8/1725 74/18639 0.108108108108108 1.16813160987074 0.377414492325448 0.919251444556014 GO:0048029 monosaccharide binding 8/1725 74/18639 0.108108108108108 1.16813160987074 0.377414492325448 0.919251444556014 GO:0002020 protease binding 14/1725 136/18639 0.102941176470588 1.11230179028133 0.379049713143408 0.919251444556014 GO:0140789 histone phosphatase activity 14/1725 136/18639 0.102941176470588 1.11230179028133 0.379049713143408 0.919251444556014 GO:0003925 G protein activity 6/1725 54/18639 0.111111111111111 1.20057971014493 0.383431144154108 0.919251444556014 GO:0051287 NAD binding 6/1725 54/18639 0.111111111111111 1.20057971014493 0.383431144154108 0.919251444556014 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/1725 24/18639 0.125 1.35065217391304 0.385727137125409 0.919251444556014 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/1725 24/18639 0.125 1.35065217391304 0.385727137125409 0.919251444556014 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/1725 24/18639 0.125 1.35065217391304 0.385727137125409 0.919251444556014 GO:0004622 lysophospholipase activity 3/1725 24/18639 0.125 1.35065217391304 0.385727137125409 0.919251444556014 GO:0015295 solute:proton symporter activity 3/1725 24/18639 0.125 1.35065217391304 0.385727137125409 0.919251444556014 GO:0030552 cAMP binding 3/1725 24/18639 0.125 1.35065217391304 0.385727137125409 0.919251444556014 GO:0001046 core promoter sequence-specific DNA binding 5/1725 44/18639 0.113636363636364 1.22786561264822 0.385792027239145 0.919251444556014 GO:0019205 nucleobase-containing compound kinase activity 5/1725 44/18639 0.113636363636364 1.22786561264822 0.385792027239145 0.919251444556014 GO:0030547 signaling receptor inhibitor activity 5/1725 44/18639 0.113636363636364 1.22786561264822 0.385792027239145 0.919251444556014 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 47/1725 484/18639 0.0971074380165289 1.04926697808121 0.38585710555394 0.919251444556014 GO:0008376 acetylgalactosaminyltransferase activity 4/1725 34/18639 0.117647058823529 1.27120204603581 0.387053239813059 0.919251444556014 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 4/1725 34/18639 0.117647058823529 1.27120204603581 0.387053239813059 0.919251444556014 GO:0030332 cyclin binding 4/1725 34/18639 0.117647058823529 1.27120204603581 0.387053239813059 0.919251444556014 GO:0090482 vitamin transmembrane transporter activity 4/1725 34/18639 0.117647058823529 1.27120204603581 0.387053239813059 0.919251444556014 GO:0004497 monooxygenase activity 11/1725 106/18639 0.10377358490566 1.12129614438064 0.391826973296668 0.927547108126918 GO:0019209 kinase activator activity 15/1725 148/18639 0.101351351351351 1.09512338425382 0.395640720744452 0.927547108126918 GO:0038024 cargo receptor activity 7/1725 65/18639 0.107692307692308 1.16363879598662 0.39618095171413 0.927547108126918 GO:1990782 protein tyrosine kinase binding 12/1725 117/18639 0.102564102564103 1.10822742474916 0.399002118726557 0.927547108126918 GO:0046915 transition metal ion transmembrane transporter activity 5/1725 45/18639 0.111111111111111 1.20057971014493 0.40476112507913 0.927547108126918 GO:0031490 chromatin DNA binding 13/1725 128/18639 0.1015625 1.09740489130435 0.405374558970283 0.927547108126918 GO:0022836 gated channel activity 31/1725 318/18639 0.0974842767295598 1.05333880229696 0.407798111652026 0.927547108126918 GO:0000175 3'-5'-RNA exonuclease activity 4/1725 35/18639 0.114285714285714 1.23488198757764 0.408700683757498 0.927547108126918 GO:0004129 cytochrome-c oxidase activity 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0005523 tropomyosin binding 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0010181 FMN binding 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0015250 water channel activity 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0017081 chloride channel regulator activity 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0031005 filamin binding 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0033130 acetylcholine receptor binding 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0034483 heparan sulfate sulfotransferase activity 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0050780 dopamine receptor binding 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0051371 muscle alpha-actinin binding 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0140161 monocarboxylate:sodium symporter activity 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0140776 protein-containing complex destabilizing activity 2/1725 15/18639 0.133333333333333 1.44069565217391 0.410600947973263 0.927547108126918 GO:0030295 protein kinase activator activity 14/1725 139/18639 0.100719424460432 1.08829527682202 0.411095256478313 0.927547108126918 GO:0003707 nuclear steroid receptor activity 3/1725 25/18639 0.12 1.29662608695652 0.411575558909758 0.927547108126918 GO:0015271 outward rectifier potassium channel activity 3/1725 25/18639 0.12 1.29662608695652 0.411575558909758 0.927547108126918 GO:0015296 monoatomic anion:monoatomic cation symporter activity 3/1725 25/18639 0.12 1.29662608695652 0.411575558909758 0.927547108126918 GO:0019211 phosphatase activator activity 3/1725 25/18639 0.12 1.29662608695652 0.411575558909758 0.927547108126918 GO:0019207 kinase regulator activity 28/1725 287/18639 0.0975609756097561 1.05416755037116 0.413456826467601 0.930089582308719 GO:0016757 glycosyltransferase activity 26/1725 267/18639 0.0973782771535581 1.05219345383488 0.422613323420748 0.947840615032921 GO:0004197 cysteine-type endopeptidase activity 9/1725 88/18639 0.102272727272727 1.1050790513834 0.428484571460725 0.947840615032921 GO:0005484 SNAP receptor activity 4/1725 36/18639 0.111111111111111 1.20057971014493 0.430187297630839 0.947840615032921 GO:0008236 serine-type peptidase activity 19/1725 194/18639 0.0979381443298969 1.05824294038548 0.433118107547554 0.947840615032921 GO:0046873 metal ion transmembrane transporter activity 43/1725 450/18639 0.0955555555555556 1.03249855072464 0.435898921323517 0.947840615032921 GO:0008143 poly(A) binding 3/1725 26/18639 0.115384615384615 1.24675585284281 0.437072469882635 0.947840615032921 GO:0015216 purine nucleotide transmembrane transporter activity 3/1725 26/18639 0.115384615384615 1.24675585284281 0.437072469882635 0.947840615032921 GO:0034237 protein kinase A regulatory subunit binding 3/1725 26/18639 0.115384615384615 1.24675585284281 0.437072469882635 0.947840615032921 GO:0050750 low-density lipoprotein particle receptor binding 3/1725 26/18639 0.115384615384615 1.24675585284281 0.437072469882635 0.947840615032921 GO:0052742 phosphatidylinositol kinase activity 3/1725 26/18639 0.115384615384615 1.24675585284281 0.437072469882635 0.947840615032921 GO:0070006 metalloaminopeptidase activity 3/1725 26/18639 0.115384615384615 1.24675585284281 0.437072469882635 0.947840615032921 GO:0005504 fatty acid binding 5/1725 47/18639 0.106382978723404 1.14949121184089 0.442433955946163 0.947840615032921 GO:0043495 protein-membrane adaptor activity 5/1725 47/18639 0.106382978723404 1.14949121184089 0.442433955946163 0.947840615032921 GO:0140938 histone H3 methyltransferase activity 5/1725 47/18639 0.106382978723404 1.14949121184089 0.442433955946163 0.947840615032921 GO:0000062 fatty-acyl-CoA binding 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0005159 insulin-like growth factor receptor binding 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0005521 lamin binding 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0015562 efflux transmembrane transporter activity 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0016722 oxidoreductase activity, acting on metal ions 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0019841 retinol binding 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0022841 potassium ion leak channel activity 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0070411 I-SMAD binding 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0097027 ubiquitin-protein transferase activator activity 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0140328 floppase activity 2/1725 16/18639 0.125 1.35065217391304 0.443604757480994 0.947840615032921 GO:0033293 monocarboxylic acid binding 8/1725 79/18639 0.10126582278481 1.09419922949917 0.449815457488134 0.959450932638766 GO:0008408 3'-5' exonuclease activity 6/1725 58/18639 0.103448275862069 1.11778110944528 0.451410310408772 0.959641264701685 GO:0043394 proteoglycan binding 4/1725 37/18639 0.108108108108108 1.16813160987074 0.451458765013505 0.959641264701685 GO:0016879 ligase activity, forming carbon-nitrogen bonds 5/1725 48/18639 0.104166666666667 1.12554347826087 0.46106090765558 0.97370037621566 GO:0032266 phosphatidylinositol-3-phosphate binding 5/1725 48/18639 0.104166666666667 1.12554347826087 0.46106090765558 0.97370037621566 GO:0038187 pattern recognition receptor activity 5/1725 48/18639 0.104166666666667 1.12554347826087 0.46106090765558 0.97370037621566 GO:0015252 proton channel activity 3/1725 27/18639 0.111111111111111 1.20057971014493 0.462138678993461 0.97370037621566 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 3/1725 27/18639 0.111111111111111 1.20057971014493 0.462138678993461 0.97370037621566 GO:0019955 cytokine binding 14/1725 144/18639 0.0972222222222222 1.05050724637681 0.464646323089016 0.97370037621566 GO:0004879 nuclear receptor activity 6/1725 59/18639 0.101694915254237 1.09883566691231 0.468184097592709 0.97370037621566 GO:0017171 serine hydrolase activity 19/1725 198/18639 0.095959595959596 1.03686429512516 0.46965152769226 0.97370037621566 GO:0005109 frizzled binding 4/1725 38/18639 0.105263157894737 1.13739130434783 0.472465511145817 0.97370037621566 GO:0005501 retinoid binding 4/1725 38/18639 0.105263157894737 1.13739130434783 0.472465511145817 0.97370037621566 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 4/1725 38/18639 0.105263157894737 1.13739130434783 0.472465511145817 0.97370037621566 GO:0019840 isoprenoid binding 4/1725 38/18639 0.105263157894737 1.13739130434783 0.472465511145817 0.97370037621566 GO:0008238 exopeptidase activity 10/1725 102/18639 0.0980392156862745 1.05933503836317 0.473231162285369 0.97370037621566 GO:0008194 UDP-glycosyltransferase activity 14/1725 145/18639 0.096551724137931 1.04326236881559 0.475307959390619 0.97370037621566 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1725 17/18639 0.117647058823529 1.27120204603581 0.475551740927595 0.97370037621566 GO:0036041 long-chain fatty acid binding 2/1725 17/18639 0.117647058823529 1.27120204603581 0.475551740927595 0.97370037621566 GO:0045125 bioactive lipid receptor activity 2/1725 17/18639 0.117647058823529 1.27120204603581 0.475551740927595 0.97370037621566 GO:0048038 quinone binding 2/1725 17/18639 0.117647058823529 1.27120204603581 0.475551740927595 0.97370037621566 GO:0070492 oligosaccharide binding 2/1725 17/18639 0.117647058823529 1.27120204603581 0.475551740927595 0.97370037621566 GO:1901567 fatty acid derivative binding 2/1725 17/18639 0.117647058823529 1.27120204603581 0.475551740927595 0.97370037621566 GO:1990226 histone methyltransferase binding 2/1725 17/18639 0.117647058823529 1.27120204603581 0.475551740927595 0.97370037621566 GO:0046943 carboxylic acid transmembrane transporter activity 18/1725 188/18639 0.0957446808510638 1.0345420906568 0.47632014691931 0.97370037621566 GO:0016763 pentosyltransferase activity 5/1725 49/18639 0.102040816326531 1.10257320319432 0.479501226419181 0.97370037621566 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 6/1725 60/18639 0.1 1.08052173913043 0.484815428291582 0.97370037621566 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1725 60/18639 0.1 1.08052173913043 0.484815428291582 0.97370037621566 GO:0098531 ligand-modulated transcription factor activity 6/1725 60/18639 0.1 1.08052173913043 0.484815428291582 0.97370037621566 GO:0005342 organic acid transmembrane transporter activity 18/1725 189/18639 0.0952380952380952 1.02906832298137 0.485663766566358 0.97370037621566 GO:0015293 symporter activity 14/1725 146/18639 0.0958904109589041 1.03611673615247 0.485936084932245 0.97370037621566 GO:0045499 chemorepellent activity 3/1725 28/18639 0.107142857142857 1.15770186335404 0.486705503280608 0.97370037621566 GO:0046875 ephrin receptor binding 3/1725 28/18639 0.107142857142857 1.15770186335404 0.486705503280608 0.97370037621566 GO:0051959 dynein light intermediate chain binding 3/1725 28/18639 0.107142857142857 1.15770186335404 0.486705503280608 0.97370037621566 GO:0097718 disordered domain specific binding 3/1725 28/18639 0.107142857142857 1.15770186335404 0.486705503280608 0.97370037621566 GO:0051213 dioxygenase activity 9/1725 93/18639 0.0967741935483871 1.04566619915849 0.495755109384939 0.97370037621566 GO:0015085 calcium ion transmembrane transporter activity 14/1725 147/18639 0.0952380952380952 1.02906832298137 0.496523604784127 0.97370037621566 GO:0001221 transcription coregulator binding 11/1725 115/18639 0.0956521739130435 1.03354253308129 0.500920415575174 0.97370037621566 GO:0019905 syntaxin binding 6/1725 61/18639 0.0983606557377049 1.06280826799715 0.501280013561343 0.97370037621566 GO:0005372 water transmembrane transporter activity 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0008409 5'-3' exonuclease activity 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0015280 ligand-gated sodium channel activity 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0016854 racemase and epimerase activity 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0017075 syntaxin-1 binding 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0017128 phospholipid scramblase activity 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0034185 apolipoprotein binding 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0070064 proline-rich region binding 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0070628 proteasome binding 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:1990381 ubiquitin-specific protease binding 2/1725 18/18639 0.111111111111111 1.20057971014493 0.506354773783525 0.97370037621566 GO:0003785 actin monomer binding 3/1725 29/18639 0.103448275862069 1.11778110944528 0.510714163731204 0.97370037621566 GO:0004181 metallocarboxypeptidase activity 3/1725 29/18639 0.103448275862069 1.11778110944528 0.510714163731204 0.97370037621566 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/1725 29/18639 0.103448275862069 1.11778110944528 0.510714163731204 0.97370037621566 GO:0016417 S-acyltransferase activity 3/1725 29/18639 0.103448275862069 1.11778110944528 0.510714163731204 0.97370037621566 GO:0035250 UDP-galactosyltransferase activity 3/1725 29/18639 0.103448275862069 1.11778110944528 0.510714163731204 0.97370037621566 GO:0043236 laminin binding 3/1725 29/18639 0.103448275862069 1.11778110944528 0.510714163731204 0.97370037621566 GO:0097472 cyclin-dependent protein kinase activity 3/1725 29/18639 0.103448275862069 1.11778110944528 0.510714163731204 0.97370037621566 GO:0099604 ligand-gated calcium channel activity 3/1725 29/18639 0.103448275862069 1.11778110944528 0.510714163731204 0.97370037621566 GO:0015294 solute:monoatomic cation symporter activity 11/1725 116/18639 0.0948275862068965 1.02463268365817 0.512813357430895 0.97370037621566 GO:0004532 RNA exonuclease activity 4/1725 40/18639 0.1 1.08052173913043 0.513509938483131 0.97370037621566 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/1725 40/18639 0.1 1.08052173913043 0.513509938483131 0.97370037621566 GO:0042826 histone deacetylase binding 12/1725 127/18639 0.094488188976378 1.02096542280041 0.514501749344205 0.97370037621566 GO:0005021 vascular endothelial growth factor receptor activity 5/1725 51/18639 0.0980392156862745 1.05933503836317 0.515696396825265 0.97370037621566 GO:0030544 Hsp70 protein binding 5/1725 51/18639 0.0980392156862745 1.05933503836317 0.515696396825265 0.97370037621566 GO:0015079 potassium ion transmembrane transporter activity 15/1725 160/18639 0.09375 1.01298913043478 0.518941907459206 0.97370037621566 GO:0051117 ATPase binding 8/1725 84/18639 0.0952380952380952 1.02906832298137 0.520706145254959 0.97370037621566 GO:0019842 vitamin binding 14/1725 150/18639 0.0933333333333333 1.00848695652174 0.5279743918575 0.97370037621566 GO:0030159 signaling receptor complex adaptor activity 5/1725 52/18639 0.0961538461538462 1.03896321070234 0.533394894915868 0.97370037621566 GO:0001530 lipopolysaccharide binding 4/1725 41/18639 0.0975609756097561 1.05416755037116 0.533471569309127 0.97370037621566 GO:0015215 nucleotide transmembrane transporter activity 3/1725 30/18639 0.1 1.08052173913043 0.534115141845322 0.97370037621566 GO:0016769 transferase activity, transferring nitrogenous groups 3/1725 30/18639 0.1 1.08052173913043 0.534115141845322 0.97370037621566 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/1725 30/18639 0.1 1.08052173913043 0.534115141845322 0.97370037621566 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0015245 fatty acid transmembrane transporter activity 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0016918 retinal binding 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0022840 leak channel activity 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0022842 narrow pore channel activity 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0030506 ankyrin binding 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0046624 sphingolipid transporter activity 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0050145 nucleoside monophosphate kinase activity 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0070003 threonine-type peptidase activity 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0120227 acyl-CoA binding 2/1725 19/18639 0.105263157894737 1.13739130434783 0.535951888001789 0.97370037621566 GO:0004713 protein tyrosine kinase activity 13/1725 140/18639 0.0928571428571429 1.00334161490683 0.537662849800065 0.97370037621566 GO:0008083 growth factor activity 15/1725 162/18639 0.0925925925925926 1.00048309178744 0.539003450001997 0.97370037621566 GO:0005496 steroid binding 10/1725 108/18639 0.0925925925925926 1.00048309178744 0.547900115381248 0.97370037621566 GO:0016298 lipase activity 12/1725 130/18639 0.0923076923076923 0.997404682274248 0.548116618558937 0.97370037621566 GO:0035198 miRNA binding 4/1725 42/18639 0.0952380952380952 1.02906832298137 0.553016101801959 0.97370037621566 GO:0051879 Hsp90 protein binding 4/1725 42/18639 0.0952380952380952 1.02906832298137 0.553016101801959 0.97370037621566 GO:0016411 acylglycerol O-acyltransferase activity 3/1725 31/18639 0.0967741935483871 1.04566619915849 0.556867514971983 0.97370037621566 GO:0016878 acid-thiol ligase activity 3/1725 31/18639 0.0967741935483871 1.04566619915849 0.556867514971983 0.97370037621566 GO:0047499 calcium-independent phospholipase A2 activity 3/1725 31/18639 0.0967741935483871 1.04566619915849 0.556867514971983 0.97370037621566 GO:0070273 phosphatidylinositol-4-phosphate binding 3/1725 31/18639 0.0967741935483871 1.04566619915849 0.556867514971983 0.97370037621566 GO:0070325 lipoprotein particle receptor binding 3/1725 31/18639 0.0967741935483871 1.04566619915849 0.556867514971983 0.97370037621566 GO:0020037 heme binding 13/1725 142/18639 0.0915492957746479 0.989210042865891 0.558930306540975 0.97370037621566 GO:0031072 heat shock protein binding 12/1725 131/18639 0.0916030534351145 0.989790906073681 0.559138616932295 0.97370037621566 GO:0004620 phospholipase activity 10/1725 109/18639 0.0917431192660551 0.991304347826087 0.559972892483423 0.97370037621566 GO:0005249 voltage-gated potassium channel activity 9/1725 98/18639 0.0918367346938776 0.992315882874889 0.560684985913267 0.97370037621566 GO:0017022 myosin binding 7/1725 76/18639 0.0921052631578947 0.995217391304348 0.563077502015855 0.97370037621566 GO:0001614 purinergic nucleotide receptor activity 2/1725 20/18639 0.1 1.08052173913043 0.564302366400088 0.97370037621566 GO:0001972 retinoic acid binding 2/1725 20/18639 0.1 1.08052173913043 0.564302366400088 0.97370037621566 GO:0015095 magnesium ion transmembrane transporter activity 2/1725 20/18639 0.1 1.08052173913043 0.564302366400088 0.97370037621566 GO:0016502 nucleotide receptor activity 2/1725 20/18639 0.1 1.08052173913043 0.564302366400088 0.97370037621566 GO:0030742 GTP-dependent protein binding 2/1725 20/18639 0.1 1.08052173913043 0.564302366400088 0.97370037621566 GO:0017069 snRNA binding 5/1725 54/18639 0.0925925925925926 1.00048309178744 0.567871849253885 0.97370037621566 GO:0050661 NADP binding 5/1725 54/18639 0.0925925925925926 1.00048309178744 0.567871849253885 0.97370037621566 GO:0031406 carboxylic acid binding 17/1725 187/18639 0.0909090909090909 0.982292490118577 0.568129188738828 0.97370037621566 GO:0004252 serine-type endopeptidase activity 16/1725 176/18639 0.0909090909090909 0.982292490118577 0.5683137089125 0.97370037621566 GO:0005506 iron ion binding 14/1725 154/18639 0.0909090909090909 0.982292490118577 0.568944126868327 0.97370037621566 GO:0008017 microtubule binding 25/1725 276/18639 0.0905797101449275 0.978733459357278 0.576001428808467 0.97370037621566 GO:0015291 secondary active transmembrane transporter activity 26/1725 287/18639 0.0905923344947735 0.978869868201788 0.576034331678727 0.97370037621566 GO:0008378 galactosyltransferase activity 3/1725 32/18639 0.09375 1.01298913043478 0.578938284961756 0.97370037621566 GO:0022884 macromolecule transmembrane transporter activity 3/1725 32/18639 0.09375 1.01298913043478 0.578938284961756 0.97370037621566 GO:0043425 bHLH transcription factor binding 3/1725 32/18639 0.09375 1.01298913043478 0.578938284961756 0.97370037621566 GO:0071813 lipoprotein particle binding 3/1725 32/18639 0.09375 1.01298913043478 0.578938284961756 0.97370037621566 GO:0071814 protein-lipid complex binding 3/1725 32/18639 0.09375 1.01298913043478 0.578938284961756 0.97370037621566 GO:0008235 metalloexopeptidase activity 6/1725 66/18639 0.0909090909090909 0.982292490118577 0.580365184219785 0.97370037621566 GO:0008528 G protein-coupled peptide receptor activity 11/1725 122/18639 0.0901639344262295 0.97424091233072 0.582142364103425 0.97370037621566 GO:0019887 protein kinase regulator activity 23/1725 255/18639 0.0901960784313725 0.974588235294118 0.583853100651227 0.97370037621566 GO:0098632 cell-cell adhesion mediator activity 5/1725 55/18639 0.0909090909090909 0.982292490118577 0.584608962471575 0.97370037621566 GO:0140313 molecular sequestering activity 5/1725 55/18639 0.0909090909090909 0.982292490118577 0.584608962471575 0.97370037621566 GO:0043177 organic acid binding 17/1725 189/18639 0.0899470899470899 0.971897860593513 0.586309164042157 0.97370037621566 GO:0043014 alpha-tubulin binding 4/1725 44/18639 0.0909090909090909 0.982292490118577 0.590748665434692 0.97370037621566 GO:0005123 death receptor binding 2/1725 21/18639 0.0952380952380952 1.02906832298137 0.591383343840657 0.97370037621566 GO:0005248 voltage-gated sodium channel activity 2/1725 21/18639 0.0952380952380952 1.02906832298137 0.591383343840657 0.97370037621566 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/1725 21/18639 0.0952380952380952 1.02906832298137 0.591383343840657 0.97370037621566 GO:0009975 cyclase activity 2/1725 21/18639 0.0952380952380952 1.02906832298137 0.591383343840657 0.97370037621566 GO:0010314 phosphatidylinositol-5-phosphate binding 2/1725 21/18639 0.0952380952380952 1.02906832298137 0.591383343840657 0.97370037621566 GO:0019200 carbohydrate kinase activity 2/1725 21/18639 0.0952380952380952 1.02906832298137 0.591383343840657 0.97370037621566 GO:0072542 protein phosphatase activator activity 2/1725 21/18639 0.0952380952380952 1.02906832298137 0.591383343840657 0.97370037621566 GO:0170055 lipid transmembrane transporter activity 5/1725 56/18639 0.0892857142857143 0.964751552795031 0.600988229532079 0.97370037621566 GO:0008514 organic anion transmembrane transporter activity 24/1725 269/18639 0.0892193308550186 0.964034265395183 0.606333943749523 0.97370037621566 GO:0051539 4 iron, 4 sulfur cluster binding 4/1725 45/18639 0.0888888888888889 0.960463768115942 0.60889379132304 0.97370037621566 GO:0140303 intramembrane lipid transporter activity 4/1725 45/18639 0.0888888888888889 0.960463768115942 0.60889379132304 0.97370037621566 GO:0005548 phospholipid transporter activity 6/1725 68/18639 0.0882352941176471 0.953401534526854 0.610163322145858 0.97370037621566 GO:0030145 manganese ion binding 6/1725 68/18639 0.0882352941176471 0.953401534526854 0.610163322145858 0.97370037621566 GO:0099094 ligand-gated monoatomic cation channel activity 12/1725 136/18639 0.0882352941176471 0.953401534526854 0.612572229296643 0.97370037621566 GO:0004407 histone deacetylase activity 2/1725 22/18639 0.0909090909090909 0.982292490118577 0.617186854934831 0.97370037621566 GO:0008093 cytoskeletal anchor activity 2/1725 22/18639 0.0909090909090909 0.982292490118577 0.617186854934831 0.97370037621566 GO:0016881 acid-amino acid ligase activity 2/1725 22/18639 0.0909090909090909 0.982292490118577 0.617186854934831 0.97370037621566 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1725 22/18639 0.0909090909090909 0.982292490118577 0.617186854934831 0.97370037621566 GO:0031683 G-protein beta/gamma-subunit complex binding 2/1725 22/18639 0.0909090909090909 0.982292490118577 0.617186854934831 0.97370037621566 GO:0033558 protein lysine deacetylase activity 2/1725 22/18639 0.0909090909090909 0.982292490118577 0.617186854934831 0.97370037621566 GO:0061133 endopeptidase activator activity 2/1725 22/18639 0.0909090909090909 0.982292490118577 0.617186854934831 0.97370037621566 GO:0005216 monoatomic ion channel activity 40/1725 448/18639 0.0892857142857143 0.964751552795031 0.619566562687573 0.97370037621566 GO:0015035 protein-disulfide reductase activity 3/1725 34/18639 0.0882352941176471 0.953401534526854 0.620938660594875 0.97370037621566 GO:0001094 TFIID-class transcription factor complex binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0004090 carbonyl reductase (NADPH) activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0004935 adrenergic receptor activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0004983 neuropeptide Y receptor activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0005337 nucleoside transmembrane transporter activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0005345 purine nucleobase transmembrane transporter activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0008519 ammonium channel activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0015203 polyamine transmembrane transporter activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0015643 toxic substance binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0019911 structural constituent of myelin sheath 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0031996 thioesterase binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0032356 oxidized DNA binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0042166 acetylcholine binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0050308 sugar-phosphatase activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0050815 phosphoserine residue binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0051378 serotonin binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0051880 G-quadruplex DNA binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0097177 mitochondrial ribosome binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0098505 G-rich strand telomeric DNA binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0099122 RNA polymerase II C-terminal domain binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0140999 histone H3K4 trimethyltransferase activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:1990757 ubiquitin ligase activator activity 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:1990763 arrestin family protein binding 1/1725 10/18639 0.1 1.08052173913043 0.621443936614551 0.97370037621566 GO:0016922 nuclear receptor binding 12/1725 137/18639 0.0875912408759124 0.946442399238337 0.622882228357229 0.97370037621566 GO:0030276 clathrin binding 4/1725 46/18639 0.0869565217391304 0.939584120982987 0.626535582978994 0.97370037621566 GO:0004623 phospholipase A2 activity 3/1725 35/18639 0.0857142857142857 0.92616149068323 0.64083597092338 0.97370037621566 GO:0043015 gamma-tubulin binding 3/1725 35/18639 0.0857142857142857 0.92616149068323 0.64083597092338 0.97370037621566 GO:0061631 ubiquitin conjugating enzyme activity 3/1725 35/18639 0.0857142857142857 0.92616149068323 0.64083597092338 0.97370037621566 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1725 23/18639 0.0869565217391304 0.939584120982987 0.64171727480543 0.97370037621566 GO:0004602 glutathione peroxidase activity 2/1725 23/18639 0.0869565217391304 0.939584120982987 0.64171727480543 0.97370037621566 GO:0031681 G-protein beta-subunit binding 2/1725 23/18639 0.0869565217391304 0.939584120982987 0.64171727480543 0.97370037621566 GO:0043274 phospholipase binding 2/1725 23/18639 0.0869565217391304 0.939584120982987 0.64171727480543 0.97370037621566 GO:0070577 lysine-acetylated histone binding 2/1725 23/18639 0.0869565217391304 0.939584120982987 0.64171727480543 0.97370037621566 GO:0070851 growth factor receptor binding 12/1725 139/18639 0.0863309352517986 0.932824522990303 0.643084264351772 0.97370037621566 GO:0001784 phosphotyrosine residue binding 4/1725 47/18639 0.0851063829787234 0.919592969472711 0.643661315726234 0.97370037621566 GO:0001653 peptide receptor activity 11/1725 128/18639 0.0859375 0.928573369565217 0.646830262603478 0.97370037621566 GO:0001664 G protein-coupled receptor binding 26/1725 297/18639 0.0875420875420875 0.945911286780852 0.647402505845611 0.97370037621566 GO:0045309 protein phosphorylated amino acid binding 5/1725 59/18639 0.0847457627118644 0.915696389093589 0.647841146653789 0.97370037621566 GO:0008013 beta-catenin binding 9/1725 106/18639 0.0849056603773585 0.917424118129614 0.656331072750952 0.97370037621566 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0002162 dystroglycan binding 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0004016 adenylate cyclase activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0005225 volume-sensitive anion channel activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0008503 benzodiazepine receptor activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0008526 phosphatidylinositol transfer activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0010854 adenylate cyclase regulator activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0015205 nucleobase transmembrane transporter activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0015217 ADP transmembrane transporter activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0019203 carbohydrate phosphatase activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0019206 nucleoside kinase activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0019215 intermediate filament binding 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0031731 CCR6 chemokine receptor binding 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0032050 clathrin heavy chain binding 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0034511 U3 snoRNA binding 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0045294 alpha-catenin binding 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0070697 activin receptor binding 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0070990 snRNP binding 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0140537 transcription regulator activator activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:1990948 ubiquitin ligase inhibitor activity 1/1725 11/18639 0.0909090909090909 0.982292490118577 0.656497305520016 0.97370037621566 GO:0046906 tetrapyrrole binding 13/1725 152/18639 0.0855263157894737 0.924130434782609 0.658824346090253 0.97370037621566 GO:0045505 dynein intermediate chain binding 3/1725 36/18639 0.0833333333333333 0.900434782608696 0.65998585031361 0.97370037621566 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/1725 36/18639 0.0833333333333333 0.900434782608696 0.65998585031361 0.97370037621566 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/1725 36/18639 0.0833333333333333 0.900434782608696 0.65998585031361 0.97370037621566 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/1725 36/18639 0.0833333333333333 0.900434782608696 0.65998585031361 0.97370037621566 GO:0005315 phosphate transmembrane transporter activity 2/1725 24/18639 0.0833333333333333 0.900434782608696 0.664989105503614 0.97370037621566 GO:0005540 hyaluronic acid binding 2/1725 24/18639 0.0833333333333333 0.900434782608696 0.664989105503614 0.97370037621566 GO:0030215 semaphorin receptor binding 2/1725 24/18639 0.0833333333333333 0.900434782608696 0.664989105503614 0.97370037621566 GO:0035035 histone acetyltransferase binding 2/1725 24/18639 0.0833333333333333 0.900434782608696 0.664989105503614 0.97370037621566 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/1725 24/18639 0.0833333333333333 0.900434782608696 0.664989105503614 0.97370037621566 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/1725 24/18639 0.0833333333333333 0.900434782608696 0.664989105503614 0.97370037621566 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/1725 24/18639 0.0833333333333333 0.900434782608696 0.664989105503614 0.97370037621566 GO:0070300 phosphatidic acid binding 2/1725 24/18639 0.0833333333333333 0.900434782608696 0.664989105503614 0.97370037621566 GO:0140033 acetylation-dependent protein binding 2/1725 24/18639 0.0833333333333333 0.900434782608696 0.664989105503614 0.97370037621566 GO:0005004 GPI-linked ephrin receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0005008 hepatocyte growth factor receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0005009 insulin receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0005011 macrophage colony-stimulating factor receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0005020 stem cell factor receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0008288 boss receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0036332 placental growth factor receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0038062 protein tyrosine kinase collagen receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0060175 brain-derived neurotrophic factor receptor activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0060590 ATPase regulator activity 4/1725 49/18639 0.0816326530612245 0.882058562555457 0.676328919615067 0.97370037621566 GO:0030551 cyclic nucleotide binding 3/1725 37/18639 0.0810810810810811 0.876098707403055 0.678385299016561 0.97370037621566 GO:0005537 D-mannose binding 2/1725 25/18639 0.08 0.864417391304348 0.687025066076993 0.97370037621566 GO:0008139 nuclear localization sequence binding 2/1725 25/18639 0.08 0.864417391304348 0.687025066076993 0.97370037621566 GO:0008483 transaminase activity 2/1725 25/18639 0.08 0.864417391304348 0.687025066076993 0.97370037621566 GO:0015645 fatty acid ligase activity 2/1725 25/18639 0.08 0.864417391304348 0.687025066076993 0.97370037621566 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/1725 25/18639 0.08 0.864417391304348 0.687025066076993 0.97370037621566 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/1725 25/18639 0.08 0.864417391304348 0.687025066076993 0.97370037621566 GO:0019707 protein-cysteine S-acyltransferase activity 2/1725 25/18639 0.08 0.864417391304348 0.687025066076993 0.97370037621566 GO:0042974 nuclear retinoic acid receptor binding 2/1725 25/18639 0.08 0.864417391304348 0.687025066076993 0.97370037621566 GO:0120515 fatty acid-CoA ligase activity 2/1725 25/18639 0.08 0.864417391304348 0.687025066076993 0.97370037621566 GO:0003720 telomerase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0004000 adenosine deaminase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0004875 complement receptor activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0005049 nuclear export signal receptor activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0005436 sodium:phosphate symporter activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0008504 monoamine transmembrane transporter activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0016208 AMP binding 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0016801 hydrolase activity, acting on ether bonds 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0016803 ether hydrolase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0016840 carbon-nitrogen lyase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0034452 dynactin binding 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0035259 nuclear glucocorticoid receptor binding 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0035497 cAMP response element binding 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0045295 gamma-catenin binding 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0070008 serine-type exopeptidase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0070410 co-SMAD binding 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0097677 STAT family protein binding 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:1990459 transferrin receptor binding 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:1990817 poly(A) RNA polymerase activity 1/1725 12/18639 0.0833333333333333 0.900434782608696 0.688306525402879 0.97370037621566 GO:0005006 epidermal growth factor receptor activity 4/1725 50/18639 0.08 0.864417391304348 0.691859879956164 0.97370037621566 GO:0005007 fibroblast growth factor receptor activity 4/1725 50/18639 0.08 0.864417391304348 0.691859879956164 0.97370037621566 GO:0005017 platelet-derived growth factor receptor activity 4/1725 50/18639 0.08 0.864417391304348 0.691859879956164 0.97370037621566 GO:0005019 platelet-derived growth factor beta-receptor activity 4/1725 50/18639 0.08 0.864417391304348 0.691859879956164 0.97370037621566 GO:0061134 peptidase regulator activity 19/1725 226/18639 0.084070796460177 0.908403232012313 0.704137312645005 0.97370037621566 GO:0019003 GDP binding 6/1725 75/18639 0.08 0.864417391304348 0.704478509709988 0.97370037621566 GO:0005030 neurotrophin receptor activity 4/1725 51/18639 0.0784313725490196 0.847468030690537 0.706852516818368 0.97370037621566 GO:0005048 signal sequence binding 4/1725 51/18639 0.0784313725490196 0.847468030690537 0.706852516818368 0.97370037621566 GO:0004529 DNA exonuclease activity 2/1725 26/18639 0.0769230769230769 0.831170568561873 0.707854449093189 0.97370037621566 GO:0030247 polysaccharide binding 2/1725 26/18639 0.0769230769230769 0.831170568561873 0.707854449093189 0.97370037621566 GO:0097602 cullin family protein binding 2/1725 26/18639 0.0769230769230769 0.831170568561873 0.707854449093189 0.97370037621566 GO:0120014 phospholipid transfer activity 2/1725 26/18639 0.0769230769230769 0.831170568561873 0.707854449093189 0.97370037621566 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/1725 39/18639 0.0769230769230769 0.831170568561873 0.712941642230377 0.97370037621566 GO:0003964 RNA-directed DNA polymerase activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0004465 lipoprotein lipase activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0004993 G protein-coupled serotonin receptor activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0008035 high-density lipoprotein particle binding 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0008253 5'-nucleotidase activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0008417 fucosyltransferase activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0017154 semaphorin receptor activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0019104 DNA N-glycosylase activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0097157 pre-mRNA intronic binding 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0140333 glycerophospholipid flippase activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:1901338 catecholamine binding 1/1725 13/18639 0.0769230769230769 0.831170568561873 0.717171680483141 0.97370037621566 GO:0001671 ATPase activator activity 2/1725 27/18639 0.0740740740740741 0.800386473429952 0.727511710701167 0.97370037621566 GO:0005104 fibroblast growth factor receptor binding 2/1725 27/18639 0.0740740740740741 0.800386473429952 0.727511710701167 0.97370037621566 GO:0005385 zinc ion transmembrane transporter activity 2/1725 27/18639 0.0740740740740741 0.800386473429952 0.727511710701167 0.97370037621566 GO:0008320 protein transmembrane transporter activity 2/1725 27/18639 0.0740740740740741 0.800386473429952 0.727511710701167 0.97370037621566 GO:0016405 CoA-ligase activity 2/1725 27/18639 0.0740740740740741 0.800386473429952 0.727511710701167 0.97370037621566 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1725 27/18639 0.0740740740740741 0.800386473429952 0.727511710701167 0.97370037621566 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/1725 27/18639 0.0740740740740741 0.800386473429952 0.727511710701167 0.97370037621566 GO:0099106 ion channel regulator activity 13/1725 160/18639 0.08125 0.877923913043478 0.72897129888635 0.97370037621566 GO:0015036 disulfide oxidoreductase activity 3/1725 40/18639 0.075 0.810391304347826 0.729111780372046 0.97370037621566 GO:0050997 quaternary ammonium group binding 3/1725 40/18639 0.075 0.810391304347826 0.729111780372046 0.97370037621566 GO:0019843 rRNA binding 5/1725 65/18639 0.0769230769230769 0.831170568561873 0.730515768115054 0.97370037621566 GO:0120013 lipid transfer activity 5/1725 65/18639 0.0769230769230769 0.831170568561873 0.730515768115054 0.97370037621566 GO:0005003 ephrin receptor activity 4/1725 53/18639 0.0754716981132075 0.815488105004102 0.735226772721494 0.97370037621566 GO:0005005 transmembrane-ephrin receptor activity 4/1725 53/18639 0.0754716981132075 0.815488105004102 0.735226772721494 0.97370037621566 GO:0008146 sulfotransferase activity 4/1725 53/18639 0.0754716981132075 0.815488105004102 0.735226772721494 0.97370037621566 GO:0016251 RNA polymerase II general transcription initiation factor activity 4/1725 53/18639 0.0754716981132075 0.815488105004102 0.735226772721494 0.97370037621566 GO:0034212 protein N-acetyltransferase activity 4/1725 53/18639 0.0754716981132075 0.815488105004102 0.735226772721494 0.97370037621566 GO:0038064 collagen receptor activity 4/1725 53/18639 0.0754716981132075 0.815488105004102 0.735226772721494 0.97370037621566 GO:0005313 L-glutamate transmembrane transporter activity 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0008392 arachidonate epoxygenase activity 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0019992 diacylglycerol binding 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0032036 myosin heavy chain binding 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0043176 amine binding 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0044548 S100 protein binding 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0061665 SUMO ligase activity 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0098599 palmitoyl hydrolase activity 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:1901612 cardiolipin binding 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:1990825 sequence-specific mRNA binding 1/1725 14/18639 0.0714285714285714 0.771801242236025 0.743365111770941 0.97370037621566 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/1725 41/18639 0.0731707317073171 0.790625662778367 0.744557060192803 0.97370037621566 GO:0017080 sodium channel regulator activity 3/1725 41/18639 0.0731707317073171 0.790625662778367 0.744557060192803 0.97370037621566 GO:0042169 SH2 domain binding 3/1725 41/18639 0.0731707317073171 0.790625662778367 0.744557060192803 0.97370037621566 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/1725 41/18639 0.0731707317073171 0.790625662778367 0.744557060192803 0.97370037621566 GO:0019789 SUMO transferase activity 2/1725 28/18639 0.0714285714285714 0.771801242236025 0.746035265118134 0.97370037621566 GO:0036408 histone H3K14 acetyltransferase activity 2/1725 28/18639 0.0714285714285714 0.771801242236025 0.746035265118134 0.97370037621566 GO:0101005 deubiquitinase activity 9/1725 115/18639 0.0782608695652174 0.845625708884688 0.74808569721757 0.97370037621566 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/1725 54/18639 0.0740740740740741 0.800386473429952 0.748615166598902 0.97370037621566 GO:0015276 ligand-gated monoatomic ion channel activity 15/1725 186/18639 0.0806451612903226 0.871388499298738 0.749232580851648 0.97370037621566 GO:0140767 enzyme-substrate adaptor activity 11/1725 139/18639 0.079136690647482 0.855089146074445 0.749758865205401 0.97370037621566 GO:0015370 solute:sodium symporter activity 6/1725 79/18639 0.0759493670886076 0.820649422124381 0.750870412409257 0.97370037621566 GO:0016500 protein-hormone receptor activity 5/1725 67/18639 0.0746268656716418 0.806359506813757 0.754711351964838 0.97370037621566 GO:0008234 cysteine-type peptidase activity 15/1725 187/18639 0.0802139037433155 0.866728667751686 0.756432340593598 0.97370037621566 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 10/1725 128/18639 0.078125 0.844157608695652 0.757341228199178 0.97370037621566 GO:0004402 histone acetyltransferase activity 3/1725 42/18639 0.0714285714285714 0.771801242236025 0.759290980069021 0.97370037621566 GO:0016859 cis-trans isomerase activity 3/1725 42/18639 0.0714285714285714 0.771801242236025 0.759290980069021 0.97370037621566 GO:0019894 kinesin binding 3/1725 42/18639 0.0714285714285714 0.771801242236025 0.759290980069021 0.97370037621566 GO:0031492 nucleosomal DNA binding 3/1725 42/18639 0.0714285714285714 0.771801242236025 0.759290980069021 0.97370037621566 GO:0015081 sodium ion transmembrane transporter activity 13/1725 164/18639 0.0792682926829268 0.856511134676564 0.760334122832852 0.97370037621566 GO:0008374 O-acyltransferase activity 4/1725 55/18639 0.0727272727272727 0.785833992094862 0.761478398295163 0.97370037621566 GO:0010484 histone H3 acetyltransferase activity 2/1725 29/18639 0.0689655172413793 0.745187406296852 0.763466457813462 0.97370037621566 GO:0051861 glycolipid binding 2/1725 29/18639 0.0689655172413793 0.745187406296852 0.763466457813462 0.97370037621566 GO:0106222 lncRNA binding 2/1725 29/18639 0.0689655172413793 0.745187406296852 0.763466457813462 0.97370037621566 GO:0022834 ligand-gated channel activity 15/1725 188/18639 0.0797872340425532 0.862118408880666 0.763493522491936 0.97370037621566 GO:0000774 adenyl-nucleotide exchange factor activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0008020 G protein-coupled photoreceptor activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0008242 omega peptidase activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0008252 nucleotidase activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0015929 hexosaminidase activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0016846 carbon-sulfur lyase activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0031386 protein tag activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0042809 nuclear vitamin D receptor binding 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0047372 monoacylglycerol lipase activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0061578 K63-linked deubiquitinase activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0120283 protein serine/threonine kinase binding 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0141047 molecular tag activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0141050 histone H3K deacetylase activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0141051 histone H4K deacetylase activity 1/1725 15/18639 0.0666666666666667 0.720347826086956 0.767133980613633 0.97370037621566 GO:0000149 SNARE binding 8/1725 106/18639 0.0754716981132075 0.815488105004102 0.775904299542028 0.977523748050399 GO:0031210 phosphatidylcholine binding 2/1725 30/18639 0.0666666666666667 0.720347826086956 0.779848694668329 0.977523748050399 GO:0031624 ubiquitin conjugating enzyme binding 2/1725 30/18639 0.0666666666666667 0.720347826086956 0.779848694668329 0.977523748050399 GO:0043995 histone H4K5 acetyltransferase activity 2/1725 30/18639 0.0666666666666667 0.720347826086956 0.779848694668329 0.977523748050399 GO:0043996 histone H4K8 acetyltransferase activity 2/1725 30/18639 0.0666666666666667 0.720347826086956 0.779848694668329 0.977523748050399 GO:0043997 histone H4K12 acetyltransferase activity 2/1725 30/18639 0.0666666666666667 0.720347826086956 0.779848694668329 0.977523748050399 GO:0004601 peroxidase activity 4/1725 57/18639 0.0701754385964912 0.758260869565217 0.785659946888381 0.977523748050399 GO:0001223 transcription coactivator binding 3/1725 44/18639 0.0681818181818182 0.736719367588933 0.786688628206947 0.977523748050399 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1725 70/18639 0.0714285714285714 0.771801242236025 0.787896879523814 0.977523748050399 GO:0004708 MAP kinase kinase activity 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0008142 oxysterol binding 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0008296 3'-5'-DNA exonuclease activity 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0008391 arachidonate monooxygenase activity 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0015378 sodium:chloride symporter activity 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0015385 sodium:proton antiporter activity 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0017070 U6 snRNA binding 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0043023 ribosomal large subunit binding 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0140327 flippase activity 1/1725 16/18639 0.0625 0.675326086956522 0.788702595489142 0.977523748050399 GO:0016247 channel regulator activity 13/1725 168/18639 0.0773809523809524 0.83611801242236 0.789142653284411 0.977523748050399 GO:0004843 cysteine-type deubiquitinase activity 8/1725 108/18639 0.0740740740740741 0.800386473429952 0.793183448623989 0.979570253357398 GO:0017147 Wnt-protein binding 2/1725 31/18639 0.0645161290322581 0.69711079943899 0.79522670706118 0.979570253357398 GO:0004896 cytokine receptor activity 7/1725 96/18639 0.0729166666666667 0.787880434782609 0.796379532679424 0.979570253357398 GO:0061980 regulatory RNA binding 4/1725 58/18639 0.0689655172413793 0.745187406296852 0.796996537546442 0.979570253357398 GO:0046982 protein heterodimerization activity 30/1725 369/18639 0.0813008130081301 0.87847295864263 0.798744997796459 0.979570253357398 GO:0141108 transporter regulator activity 13/1725 170/18639 0.0764705882352941 0.826281329923274 0.802589606733589 0.979570253357398 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 9/1725 122/18639 0.0737704918032787 0.797106200997862 0.806691594899069 0.979570253357398 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/1725 59/18639 0.0677966101694915 0.732557111274871 0.807844202338635 0.979570253357398 GO:0070888 E-box binding 4/1725 59/18639 0.0677966101694915 0.732557111274871 0.807844202338635 0.979570253357398 GO:0005092 GDP-dissociation inhibitor activity 1/1725 17/18639 0.0588235294117647 0.635601023017903 0.808274523899239 0.979570253357398 GO:0008569 minus-end-directed microtubule motor activity 1/1725 17/18639 0.0588235294117647 0.635601023017903 0.808274523899239 0.979570253357398 GO:0009881 photoreceptor activity 1/1725 17/18639 0.0588235294117647 0.635601023017903 0.808274523899239 0.979570253357398 GO:0016805 dipeptidase activity 1/1725 17/18639 0.0588235294117647 0.635601023017903 0.808274523899239 0.979570253357398 GO:0017110 nucleoside diphosphate phosphatase activity 1/1725 17/18639 0.0588235294117647 0.635601023017903 0.808274523899239 0.979570253357398 GO:0032977 membrane insertase activity 1/1725 17/18639 0.0588235294117647 0.635601023017903 0.808274523899239 0.979570253357398 GO:0070402 NADPH binding 1/1725 17/18639 0.0588235294117647 0.635601023017903 0.808274523899239 0.979570253357398 GO:0005516 calmodulin binding 16/1725 207/18639 0.0772946859903382 0.83518588531821 0.809380544254302 0.979570253357398 GO:0031369 translation initiation factor binding 2/1725 32/18639 0.0625 0.675326086956522 0.809645935201142 0.979570253357398 GO:0047498 calcium-dependent phospholipase A2 activity 2/1725 32/18639 0.0625 0.675326086956522 0.809645935201142 0.979570253357398 GO:0120015 sterol transfer activity 2/1725 32/18639 0.0625 0.675326086956522 0.809645935201142 0.979570253357398 GO:0140142 nucleocytoplasmic carrier activity 2/1725 32/18639 0.0625 0.675326086956522 0.809645935201142 0.979570253357398 GO:0004180 carboxypeptidase activity 3/1725 46/18639 0.0652173913043478 0.70468809073724 0.811447748466471 0.979570253357398 GO:0015297 antiporter activity 10/1725 135/18639 0.0740740740740741 0.800386473429952 0.81199697194436 0.979570253357398 GO:0016209 antioxidant activity 6/1725 86/18639 0.0697674418604651 0.753852376137513 0.818852613791663 0.979570253357398 GO:0061733 protein-lysine-acetyltransferase activity 3/1725 47/18639 0.0638297872340425 0.689694727104533 0.822887732516942 0.979570253357398 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1725 33/18639 0.0606060606060606 0.654861660079051 0.823152014136547 0.979570253357398 GO:0140311 protein sequestering activity 2/1725 33/18639 0.0606060606060606 0.654861660079051 0.823152014136547 0.979570253357398 GO:0008509 monoatomic anion transmembrane transporter activity 11/1725 149/18639 0.0738255033557047 0.797700612780858 0.823854165698707 0.979570253357398 GO:0005200 structural constituent of cytoskeleton 8/1725 112/18639 0.0714285714285714 0.771801242236025 0.824722590845386 0.979570253357398 GO:0003746 translation elongation factor activity 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0004970 glutamate-gated receptor activity 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0008525 phosphatidylcholine transporter activity 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0015172 acidic amino acid transmembrane transporter activity 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0015373 monoatomic anion:sodium symporter activity 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0022851 GABA-gated chloride ion channel activity 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0032393 MHC class I receptor activity 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0035615 clathrin adaptor activity 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0050811 GABA receptor binding 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0098641 cadherin binding involved in cell-cell adhesion 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:1901611 phosphatidylglycerol binding 1/1725 18/18639 0.0555555555555556 0.600289855072464 0.826034509200163 0.979570253357398 GO:0008188 neuropeptide receptor activity 3/1725 48/18639 0.0625 0.675326086956522 0.833729491163167 0.979570253357398 GO:0003725 double-stranded RNA binding 5/1725 75/18639 0.0666666666666667 0.720347826086956 0.835290883804701 0.979570253357398 GO:0019783 ubiquitin-like protein peptidase activity 9/1725 127/18639 0.0708661417322835 0.765724067100308 0.841846535697784 0.979570253357398 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0004890 GABA-A receptor activity 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0008301 DNA binding, bending 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0008574 plus-end-directed microtubule motor activity 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0034987 immunoglobulin receptor binding 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0042800 histone H3K4 methyltransferase activity 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0042834 peptidoglycan binding 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0043395 heparan sulfate proteoglycan binding 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0097001 ceramide binding 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0099589 serotonin receptor activity 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0141147 intracellularly calcium-gated channel activity 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:1990380 K48-linked deubiquitinase activity 1/1725 19/18639 0.0526315789473684 0.568695652173913 0.842150210377851 0.979570253357398 GO:0035401 histone H3Y41 kinase activity 8/1725 115/18639 0.0695652173913043 0.751667296786389 0.845828130828342 0.979570253357398 GO:0140801 histone H2AXY142 kinase activity 8/1725 115/18639 0.0695652173913043 0.751667296786389 0.845828130828342 0.979570253357398 GO:0015103 inorganic anion transmembrane transporter activity 12/1725 165/18639 0.0727272727272727 0.785833992094862 0.846310481912325 0.979570253357398 GO:0005154 epidermal growth factor receptor binding 2/1725 35/18639 0.0571428571428571 0.61744099378882 0.847605765569842 0.979570253357398 GO:0010485 histone H4 acetyltransferase activity 2/1725 35/18639 0.0571428571428571 0.61744099378882 0.847605765569842 0.979570253357398 GO:0016229 steroid dehydrogenase activity 2/1725 35/18639 0.0571428571428571 0.61744099378882 0.847605765569842 0.979570253357398 GO:0003774 cytoskeletal motor activity 11/1725 153/18639 0.0718954248366013 0.776845694799659 0.848372816206397 0.979570253357398 GO:0032813 tumor necrosis factor receptor superfamily binding 3/1725 50/18639 0.06 0.648313043478261 0.853705481948912 0.979570253357398 GO:0005326 neurotransmitter transmembrane transporter activity 1/1725 20/18639 0.05 0.540260869565217 0.856773781113522 0.979570253357398 GO:0010851 cyclase regulator activity 1/1725 20/18639 0.05 0.540260869565217 0.856773781113522 0.979570253357398 GO:0015464 acetylcholine receptor activity 1/1725 20/18639 0.05 0.540260869565217 0.856773781113522 0.979570253357398 GO:0016004 phospholipase activator activity 1/1725 20/18639 0.05 0.540260869565217 0.856773781113522 0.979570253357398 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1725 20/18639 0.05 0.540260869565217 0.856773781113522 0.979570253357398 GO:0042288 MHC class I protein binding 1/1725 20/18639 0.05 0.540260869565217 0.856773781113522 0.979570253357398 GO:0043024 ribosomal small subunit binding 1/1725 20/18639 0.05 0.540260869565217 0.856773781113522 0.979570253357398 GO:0061608 nuclear import signal receptor activity 1/1725 20/18639 0.05 0.540260869565217 0.856773781113522 0.979570253357398 GO:0016409 palmitoyltransferase activity 2/1725 36/18639 0.0555555555555556 0.600289855072464 0.85864223117315 0.979570253357398 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/1725 36/18639 0.0555555555555556 0.600289855072464 0.85864223117315 0.979570253357398 GO:0016597 amino acid binding 3/1725 51/18639 0.0588235294117647 0.635601023017903 0.862883792269571 0.979570253357398 GO:0015631 tubulin binding 30/1725 385/18639 0.0779220779220779 0.841964991530209 0.86326022525758 0.979570253357398 GO:0022829 wide pore channel activity 2/1725 37/18639 0.0540540540540541 0.58406580493537 0.868942627296384 0.979570253357398 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1725 21/18639 0.0476190476190476 0.514534161490683 0.870043302977166 0.979570253357398 GO:0015125 bile acid transmembrane transporter activity 1/1725 21/18639 0.0476190476190476 0.514534161490683 0.870043302977166 0.979570253357398 GO:0036122 BMP binding 1/1725 21/18639 0.0476190476190476 0.514534161490683 0.870043302977166 0.979570253357398 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/1725 21/18639 0.0476190476190476 0.514534161490683 0.870043302977166 0.979570253357398 GO:0051010 microtubule plus-end binding 1/1725 21/18639 0.0476190476190476 0.514534161490683 0.870043302977166 0.979570253357398 GO:0051428 peptide hormone receptor binding 1/1725 21/18639 0.0476190476190476 0.514534161490683 0.870043302977166 0.979570253357398 GO:0140312 cargo adaptor activity 1/1725 21/18639 0.0476190476190476 0.514534161490683 0.870043302977166 0.979570253357398 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1725 67/18639 0.0597014925373134 0.645087605451006 0.878511007471423 0.979570253357398 GO:0000146 microfilament motor activity 2/1725 38/18639 0.0526315789473684 0.568695652173913 0.87854857511572 0.979570253357398 GO:0016755 aminoacyltransferase activity 39/1725 496/18639 0.0786290322580645 0.849603786816269 0.879219367337614 0.979570253357398 GO:0004842 ubiquitin-protein transferase activity 35/1725 449/18639 0.0779510022271715 0.842277524934637 0.879350221216047 0.979570253357398 GO:0005246 calcium channel regulator activity 3/1725 53/18639 0.0566037735849057 0.611616078753076 0.879731237649204 0.979570253357398 GO:0033192 calmodulin-dependent protein phosphatase activity 5/1725 81/18639 0.0617283950617284 0.666988727858293 0.880335427362092 0.979570253357398 GO:0140791 histone H2AXS140 phosphatase activity 5/1725 81/18639 0.0617283950617284 0.666988727858293 0.880335427362092 0.979570253357398 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 5/1725 81/18639 0.0617283950617284 0.666988727858293 0.880335427362092 0.979570253357398 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 5/1725 81/18639 0.0617283950617284 0.666988727858293 0.880335427362092 0.979570253357398 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 5/1725 81/18639 0.0617283950617284 0.666988727858293 0.880335427362092 0.979570253357398 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 5/1725 81/18639 0.0617283950617284 0.666988727858293 0.880335427362092 0.979570253357398 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 5/1725 81/18639 0.0617283950617284 0.666988727858293 0.880335427362092 0.979570253357398 GO:1990439 MAP kinase serine/threonine phosphatase activity 5/1725 81/18639 0.0617283950617284 0.666988727858293 0.880335427362092 0.979570253357398 GO:0008649 rRNA methyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0008970 phospholipase A1 activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0032931 histone H3K56 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0043992 histone H3K9 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0043993 histone H3K18 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0043994 histone H3K23 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0043999 histone H2AK5 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0044012 histone H2AK9 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0044014 histone H2BK5 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0044015 histone H2BK12 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0044016 histone H3K4 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0044017 histone H3K27 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0044018 histone H3K36 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0046972 histone H4K16 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0140908 histone H3K122 acetyltransferase activity 1/1725 22/18639 0.0454545454545455 0.491146245059289 0.882084086217277 0.979570253357398 GO:0004857 enzyme inhibitor activity 32/1725 416/18639 0.0769230769230769 0.831170568561873 0.886691601531244 0.979570253357398 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 5/1725 82/18639 0.0609756097560976 0.658854718981972 0.886719155381629 0.979570253357398 GO:0033549 MAP kinase phosphatase activity 5/1725 82/18639 0.0609756097560976 0.658854718981972 0.886719155381629 0.979570253357398 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/1725 54/18639 0.0555555555555556 0.600289855072464 0.887443947710986 0.979570253357398 GO:0016407 acetyltransferase activity 6/1725 96/18639 0.0625 0.675326086956522 0.889505332146033 0.979570253357398 GO:0008080 N-acetyltransferase activity 4/1725 69/18639 0.0579710144927536 0.626389413988658 0.892195353546387 0.979570253357398 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 5/1725 83/18639 0.0602409638554217 0.650916710319539 0.892808219809957 0.979570253357398 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1725 23/18639 0.0434782608695652 0.469792060491493 0.893009850372361 0.979570253357398 GO:0016917 GABA receptor activity 1/1725 23/18639 0.0434782608695652 0.469792060491493 0.893009850372361 0.979570253357398 GO:0044013 histone H2B acetyltransferase activity 1/1725 23/18639 0.0434782608695652 0.469792060491493 0.893009850372361 0.979570253357398 GO:0140102 catalytic activity, acting on a rRNA 1/1725 23/18639 0.0434782608695652 0.469792060491493 0.893009850372361 0.979570253357398 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1725 23/18639 0.0434782608695652 0.469792060491493 0.893009850372361 0.979570253357398 GO:0015144 carbohydrate transmembrane transporter activity 2/1725 40/18639 0.05 0.540260869565217 0.895836539156871 0.979570253357398 GO:0032451 demethylase activity 2/1725 40/18639 0.05 0.540260869565217 0.895836539156871 0.979570253357398 GO:0071855 neuropeptide receptor binding 2/1725 40/18639 0.05 0.540260869565217 0.895836539156871 0.979570253357398 GO:0019787 ubiquitin-like protein transferase activity 37/1725 479/18639 0.0772442588726514 0.834641009349188 0.896920147116454 0.979570253357398 GO:0005126 cytokine receptor binding 20/1725 275/18639 0.0727272727272727 0.785833992094862 0.897267961570636 0.979570253357398 GO:0016782 transferase activity, transferring sulphur-containing groups 4/1725 70/18639 0.0571428571428571 0.61744099378882 0.898516473184119 0.979570253357398 GO:0017018 myosin phosphatase activity 5/1725 84/18639 0.0595238095238095 0.643167701863354 0.898612603641159 0.979570253357398 GO:0030170 pyridoxal phosphate binding 3/1725 56/18639 0.0535714285714286 0.578850931677019 0.901553873685431 0.979570253357398 GO:0004806 triacylglycerol lipase activity 1/1725 24/18639 0.0416666666666667 0.450217391304348 0.902923795801437 0.979570253357398 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/1725 24/18639 0.0416666666666667 0.450217391304348 0.902923795801437 0.979570253357398 GO:0043998 histone H2A acetyltransferase activity 1/1725 24/18639 0.0416666666666667 0.450217391304348 0.902923795801437 0.979570253357398 GO:0060229 lipase activator activity 1/1725 24/18639 0.0416666666666667 0.450217391304348 0.902923795801437 0.979570253357398 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/1725 24/18639 0.0416666666666667 0.450217391304348 0.902923795801437 0.979570253357398 GO:0070840 dynein complex binding 1/1725 24/18639 0.0416666666666667 0.450217391304348 0.902923795801437 0.979570253357398 GO:0008227 G protein-coupled amine receptor activity 2/1725 41/18639 0.0487804878048781 0.527083775185578 0.903594461155029 0.979570253357398 GO:0042287 MHC protein binding 2/1725 41/18639 0.0487804878048781 0.527083775185578 0.903594461155029 0.979570253357398 GO:0070279 vitamin B6 binding 3/1725 57/18639 0.0526315789473684 0.568695652173913 0.907992425174156 0.979570253357398 GO:0048487 beta-tubulin binding 2/1725 42/18639 0.0476190476190476 0.514534161490683 0.910809635209329 0.979570253357398 GO:0061630 ubiquitin protein ligase activity 26/1725 353/18639 0.0736543909348442 0.795851705875108 0.911690992855105 0.979570253357398 GO:0001848 complement binding 1/1725 25/18639 0.04 0.432208695652174 0.911919576206622 0.979570253357398 GO:0005251 delayed rectifier potassium channel activity 1/1725 25/18639 0.04 0.432208695652174 0.911919576206622 0.979570253357398 GO:0015662 P-type ion transporter activity 1/1725 25/18639 0.04 0.432208695652174 0.911919576206622 0.979570253357398 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/1725 25/18639 0.04 0.432208695652174 0.911919576206622 0.979570253357398 GO:0047617 fatty acyl-CoA hydrolase activity 1/1725 25/18639 0.04 0.432208695652174 0.911919576206622 0.979570253357398 GO:0120020 cholesterol transfer activity 1/1725 25/18639 0.04 0.432208695652174 0.911919576206622 0.979570253357398 GO:0140358 P-type transmembrane transporter activity 1/1725 25/18639 0.04 0.432208695652174 0.911919576206622 0.979570253357398 GO:0008200 ion channel inhibitor activity 2/1725 43/18639 0.0465116279069767 0.502568250758342 0.917516003498045 0.979570253357398 GO:0008375 acetylglucosaminyltransferase activity 2/1725 43/18639 0.0465116279069767 0.502568250758342 0.917516003498045 0.979570253357398 GO:0036002 pre-mRNA binding 3/1725 59/18639 0.0508474576271186 0.549417833456153 0.919736168316353 0.979570253357398 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1725 26/18639 0.0384615384615385 0.415585284280936 0.920082181291159 0.979570253357398 GO:0004950 chemokine receptor activity 1/1725 26/18639 0.0384615384615385 0.415585284280936 0.920082181291159 0.979570253357398 GO:0008066 glutamate receptor activity 1/1725 26/18639 0.0384615384615385 0.415585284280936 0.920082181291159 0.979570253357398 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1725 26/18639 0.0384615384615385 0.415585284280936 0.920082181291159 0.979570253357398 GO:0016289 acyl-CoA hydrolase activity 1/1725 26/18639 0.0384615384615385 0.415585284280936 0.920082181291159 0.979570253357398 GO:0019865 immunoglobulin binding 1/1725 26/18639 0.0384615384615385 0.415585284280936 0.920082181291159 0.979570253357398 GO:0050681 nuclear androgen receptor binding 1/1725 26/18639 0.0384615384615385 0.415585284280936 0.920082181291159 0.979570253357398 GO:0051139 metal cation:proton antiporter activity 1/1725 26/18639 0.0384615384615385 0.415585284280936 0.920082181291159 0.979570253357398 GO:0004722 protein serine/threonine phosphatase activity 6/1725 103/18639 0.058252427184466 0.629430139299282 0.923690846131523 0.98009120271667 GO:0005253 monoatomic anion channel activity 6/1725 103/18639 0.058252427184466 0.629430139299282 0.923690846131523 0.98009120271667 GO:0016248 channel inhibitor activity 2/1725 44/18639 0.0454545454545455 0.491146245059289 0.923745878511906 0.98009120271667 GO:0016790 thiolester hydrolase activity 2/1725 44/18639 0.0454545454545455 0.491146245059289 0.923745878511906 0.98009120271667 GO:0044183 protein folding chaperone 4/1725 75/18639 0.0533333333333333 0.576278260869565 0.92545315554531 0.980330368636894 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1725 27/18639 0.037037037037037 0.400193236714976 0.927488737852313 0.980330368636894 GO:0023026 MHC class II protein complex binding 1/1725 27/18639 0.037037037037037 0.400193236714976 0.927488737852313 0.980330368636894 GO:0061659 ubiquitin-like protein ligase activity 27/1725 372/18639 0.0725806451612903 0.784249649368864 0.928084593369116 0.980330368636894 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/1725 45/18639 0.0444444444444444 0.480231884057971 0.929529953818835 0.980330368636894 GO:0141110 transporter inhibitor activity 2/1725 45/18639 0.0444444444444444 0.480231884057971 0.929529953818835 0.980330368636894 GO:0051536 iron-sulfur cluster binding 4/1725 76/18639 0.0526315789473684 0.568695652173913 0.929997803319158 0.980330368636894 GO:0042277 peptide binding 17/1725 249/18639 0.0682730923694779 0.737705605028811 0.930388542567334 0.980330368636894 GO:0005242 inward rectifier potassium channel activity 1/1725 28/18639 0.0357142857142857 0.385900621118012 0.934209236842467 0.980330368636894 GO:0046625 sphingolipid binding 1/1725 28/18639 0.0357142857142857 0.385900621118012 0.934209236842467 0.980330368636894 GO:0046966 nuclear thyroid hormone receptor binding 1/1725 28/18639 0.0357142857142857 0.385900621118012 0.934209236842467 0.980330368636894 GO:0051019 mitogen-activated protein kinase binding 1/1725 28/18639 0.0357142857142857 0.385900621118012 0.934209236842467 0.980330368636894 GO:0051540 metal cluster binding 4/1725 77/18639 0.051948051948052 0.561309994353473 0.934290561850708 0.980330368636894 GO:0015108 chloride transmembrane transporter activity 7/1725 121/18639 0.0578512396694215 0.625095220984549 0.93885866613935 0.98118874113222 GO:0051082 unfolded protein binding 7/1725 121/18639 0.0578512396694215 0.625095220984549 0.93885866613935 0.98118874113222 GO:0005507 copper ion binding 3/1725 63/18639 0.0476190476190476 0.514534161490683 0.939209941575557 0.98118874113222 GO:0022824 transmitter-gated monoatomic ion channel activity 3/1725 63/18639 0.0476190476190476 0.514534161490683 0.939209941575557 0.98118874113222 GO:0022835 transmitter-gated channel activity 3/1725 63/18639 0.0476190476190476 0.514534161490683 0.939209941575557 0.98118874113222 GO:0099095 ligand-gated monoatomic anion channel activity 2/1725 47/18639 0.0425531914893617 0.459796484736355 0.939875530979284 0.98118874113222 GO:0016410 N-acyltransferase activity 5/1725 94/18639 0.0531914893617021 0.574745605920444 0.943133881199333 0.983758735879372 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/1725 48/18639 0.0416666666666667 0.450217391304348 0.944490576188681 0.98387979726844 GO:0032452 histone demethylase activity 1/1725 30/18639 0.0333333333333333 0.360173913043478 0.94584024491112 0.98387979726844 GO:0033612 receptor serine/threonine kinase binding 1/1725 30/18639 0.0333333333333333 0.360173913043478 0.94584024491112 0.98387979726844 GO:0004867 serine-type endopeptidase inhibitor activity 5/1725 95/18639 0.0526315789473684 0.568695652173913 0.946436598505998 0.98387979726844 GO:0005164 tumor necrosis factor receptor binding 1/1725 31/18639 0.032258064516129 0.348555399719495 0.950860696172785 0.984336093691022 GO:0005184 neuropeptide hormone activity 1/1725 31/18639 0.032258064516129 0.348555399719495 0.950860696172785 0.984336093691022 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1725 31/18639 0.032258064516129 0.348555399719495 0.950860696172785 0.984336093691022 GO:0008327 methyl-CpG binding 1/1725 31/18639 0.032258064516129 0.348555399719495 0.950860696172785 0.984336093691022 GO:0140457 protein demethylase activity 1/1725 31/18639 0.032258064516129 0.348555399719495 0.950860696172785 0.984336093691022 GO:0030594 neurotransmitter receptor activity 5/1725 97/18639 0.0515463917525773 0.556969968623935 0.952526016670134 0.984618364192382 GO:0048020 CCR chemokine receptor binding 2/1725 50/18639 0.04 0.432208695652174 0.952727890858216 0.984618364192382 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1725 32/18639 0.03125 0.337663043478261 0.955416011042838 0.985746678060071 GO:0160041 neuropeptide activity 1/1725 32/18639 0.03125 0.337663043478261 0.955416011042838 0.985746678060071 GO:0019239 deaminase activity 1/1725 33/18639 0.0303030303030303 0.327430830039526 0.959549260946159 0.986463450084027 GO:0019956 chemokine binding 1/1725 33/18639 0.0303030303030303 0.327430830039526 0.959549260946159 0.986463450084027 GO:0061135 endopeptidase regulator activity 11/1725 184/18639 0.0597826086956522 0.645964083175803 0.959617960120331 0.986463450084027 GO:0005544 calcium-dependent phospholipid binding 2/1725 53/18639 0.0377358490566038 0.407744052502051 0.962928236609325 0.986463450084027 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/1725 53/18639 0.0377358490566038 0.407744052502051 0.962928236609325 0.986463450084027 GO:0015020 glucuronosyltransferase activity 1/1725 34/18639 0.0294117647058824 0.317800511508951 0.963299531013228 0.986463450084027 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/1725 34/18639 0.0294117647058824 0.317800511508951 0.963299531013228 0.986463450084027 GO:0019825 oxygen binding 1/1725 34/18639 0.0294117647058824 0.317800511508951 0.963299531013228 0.986463450084027 GO:0051427 hormone receptor binding 1/1725 34/18639 0.0294117647058824 0.317800511508951 0.963299531013228 0.986463450084027 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 14/1725 229/18639 0.0611353711790393 0.660580975887602 0.967494974577732 0.989415089391601 GO:0042379 chemokine receptor binding 3/1725 72/18639 0.0416666666666667 0.450217391304348 0.96813209855089 0.989415089391601 GO:0004190 aspartic-type endopeptidase activity 1/1725 36/18639 0.0277777777777778 0.300144927536232 0.969789719038879 0.989415089391601 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1725 36/18639 0.0277777777777778 0.300144927536232 0.969789719038879 0.989415089391601 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/1725 73/18639 0.0410958904109589 0.444050029779631 0.970385214371527 0.989415089391601 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/1725 56/18639 0.0357142857142857 0.385900621118012 0.970995314378976 0.989415089391601 GO:0023023 MHC protein complex binding 1/1725 37/18639 0.027027027027027 0.292032902467685 0.972591027142837 0.989415089391601 GO:0070001 aspartic-type peptidase activity 1/1725 37/18639 0.027027027027027 0.292032902467685 0.972591027142837 0.989415089391601 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/1725 40/18639 0.025 0.270130434782609 0.979531197650914 0.99475112947821 GO:0140662 ATP-dependent protein folding chaperone 1/1725 40/18639 0.025 0.270130434782609 0.979531197650914 0.99475112947821 GO:0140375 immune receptor activity 8/1725 156/18639 0.0512820512820513 0.554113712374582 0.980252732449378 0.99475112947821 GO:0140828 metal cation:monoatomic cation antiporter activity 1/1725 41/18639 0.024390243902439 0.263541887592789 0.981429616063311 0.995127730573225 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/1725 130/18639 0.0461538461538462 0.498702341137124 0.984253599184026 0.995988514392983 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/1725 43/18639 0.0232558139534884 0.251284125379171 0.984714817742693 0.995988514392983 GO:0004866 endopeptidase inhibitor activity 8/1725 161/18639 0.0496894409937888 0.536905211990278 0.985114296040157 0.995988514392983 GO:0005254 chloride channel activity 3/1725 83/18639 0.036144578313253 0.390550026191723 0.985983808092132 0.995988514392983 GO:0005125 cytokine activity 13/1725 234/18639 0.0555555555555556 0.600289855072464 0.9863108932005 0.995988514392983 GO:0008009 chemokine activity 1/1725 45/18639 0.0222222222222222 0.240115942028986 0.987419126101103 0.996287781293282 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/1725 46/18639 0.0217391304347826 0.234896030245747 0.988586277196919 0.996287781293282 GO:0003777 microtubule motor activity 2/1725 68/18639 0.0294117647058824 0.317800511508951 0.989342773861942 0.996287781293282 GO:0098960 postsynaptic neurotransmitter receptor activity 2/1725 69/18639 0.0289855072463768 0.313194706994329 0.990207867663158 0.996287781293282 GO:0030414 peptidase inhibitor activity 8/1725 169/18639 0.0473372781065089 0.51148958065346 0.990640806014697 0.996287781293282 GO:0048306 calcium-dependent protein binding 2/1725 80/18639 0.025 0.270130434782609 0.99618036581851 1 GO:0005179 hormone activity 4/1725 132/18639 0.0303030303030303 0.327430830039526 0.998677935815119 1 GO:0003735 structural constituent of ribosome 3/1725 175/18639 0.0171428571428571 0.185232298136646 0.999993090525883 1 GO:0003730 mRNA 3'-UTR binding 5/1725 262/18639 0.0190839694656489 0.20620643876535 0.999999810560545 1 GO:0003823 antigen binding 1/1725 174/18639 0.00574712643678161 0.0620989505247376 0.999999957798686 1 GO:0045182 translation regulator activity 2/1725 356/18639 0.00561797752808989 0.0607034684904739 0.999999999999974 1 GO:0004984 olfactory receptor activity 1/1725 419/18639 0.00238663484486874 0.0257881083324686 1 1