ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	66/1274	489/18639	0.134969325153374	1.97464148472036	8.20737049274905e-08	4.83439161273345e-05
GO:0060589	nucleoside-triphosphatase regulator activity	66/1274	490/18639	0.13469387755102	1.9706116041393	8.87044332611642e-08	4.83439161273345e-05
GO:0005085	guanyl-nucleotide exchange factor activity	36/1274	230/18639	0.156521739130435	2.28995972971128	2.58446297963255e-06	0.000467633140915872
GO:0106310	protein serine kinase activity	49/1274	361/18639	0.135734072022161	1.98582995951417	3.2321951672949e-06	0.000467633140915872
GO:0140996	histone H3 kinase activity	48/1274	357/18639	0.134453781512605	1.96709892748308	5.28118001803668e-06	0.000467633140915872
GO:0035403	histone H3T6 kinase activity	37/1274	247/18639	0.149797570850202	2.19158314213259	5.39943490712104e-06	0.000467633140915872
GO:0035173	histone kinase activity	48/1274	360/18639	0.133333333333333	1.95070643642072	6.64733696096625e-06	0.000467633140915872
GO:0141003	histone H2AX kinase activity	47/1274	354/18639	0.132768361581921	1.94244073118165	9.26046494052043e-06	0.000467633140915872
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	36/1274	243/18639	0.148148148148148	2.16745159602302	9.26634377085589e-06	0.000467633140915872
GO:0004676	3-phosphoinositide-dependent protein kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0004711	ribosomal protein S6 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0035175	histone H3S10 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0035979	histone H2AXS139 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0044022	histone H3S28 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0044023	histone H4S1 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0044024	histone H2AS1 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0044025	histone H2BS14 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0072354	histone H3T3 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0072371	histone H2AS121 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0072518	Rho-dependent protein serine/threonine kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0140823	histone H2BS36 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0140855	histone H3S57 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0140995	histone H2A kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0140997	histone H4 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0140998	histone H2B kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:1990244	histone H2AT120 kinase activity	36/1274	245/18639	0.146938775510204	2.14975811360651	1.11545519851492e-05	0.000467633140915872
GO:0004677	DNA-dependent protein kinase activity	36/1274	246/18639	0.146341463414634	2.14101925948616	1.22255914853442e-05	0.000475924811393754
GO:0140857	histone H3T45 kinase activity	36/1274	246/18639	0.146341463414634	2.14101925948616	1.22255914853442e-05	0.000475924811393754
GO:0035402	histone H3T11 kinase activity	36/1274	247/18639	0.145748987854251	2.1323511653182	1.33902437925291e-05	0.000503288473581267
GO:0004679	AMP-activated protein kinase activity	36/1274	248/18639	0.145161290322581	2.12375297513546	1.46558361138241e-05	0.000532495378802275
GO:0005096	GTPase activator activity	37/1274	271/18639	0.136531365313653	1.99749459817989	4.39906647369042e-05	0.0015467685342976
GO:0004674	protein serine/threonine kinase activity	52/1274	433/18639	0.120092378752887	1.75698732148749	5.21642549892336e-05	0.00177684493557077
GO:0140666	annealing activity	6/1274	13/18639	0.461538461538462	6.75244535684096	0.000113824566213138	0.00375965991431275
GO:0140938	histone H3 methyltransferase activity	11/1274	47/18639	0.234042553191489	3.42411236180233	0.000257562134353305	0.00825713901309125
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	8/1274	27/18639	0.296296296296296	4.33490319204605	0.000320022721419661	0.00996642189564088
GO:0140328	floppase activity	6/1274	16/18639	0.375	5.48636185243328	0.000444403233884495	0.0134555423592806
GO:0004407	histone deacetylase activity	7/1274	22/18639	0.318181818181818	4.6550949050949	0.000469525580094765	0.0134679705869288
GO:0033558	protein lysine deacetylase activity	7/1274	22/18639	0.318181818181818	4.6550949050949	0.000469525580094765	0.0134679705869288
GO:0035091	phosphatidylinositol binding	35/1274	284/18639	0.123239436619718	1.80302971676211	0.000516428944963304	0.0144335269233334
GO:0140097	catalytic activity, acting on DNA	39/1274	336/18639	0.116071428571429	1.69815962099125	0.000837759735691588	0.0228289527975958
GO:0016887	ATP hydrolysis activity	46/1274	417/18639	0.11031175059952	1.61389381430491	0.000909359593026336	0.0241756574731392
GO:0046975	histone H3K36 methyltransferase activity	5/1274	13/18639	0.384615384615385	5.62703779736747	0.00119783786628533	0.031086744625024
GO:0140416	transcription regulator inhibitor activity	8/1274	33/18639	0.242424242424242	3.5467389753104	0.00138688853545212	0.0351560117126236
GO:0050681	nuclear androgen receptor binding	7/1274	26/18639	0.269230769230769	3.93892645815723	0.00142314318384957	0.0352551379635462
GO:1901981	phosphatidylinositol phosphate binding	24/1274	185/18639	0.12972972972973	1.89798464084178	0.00184982885844968	0.0448069656824478
GO:1990841	promoter-specific chromatin binding	12/1274	68/18639	0.176470588235294	2.58181734232154	0.00202360567090554	0.0479506561149357
GO:0004712	protein serine/threonine/tyrosine kinase activity	9/1274	43/18639	0.209302325581395	3.0621554525209	0.0021488613594477	0.0498352953574041
GO:0002039	p53 binding	12/1274	69/18639	0.173913043478261	2.5443996996792	0.00230036263044432	0.0522374013996732
GO:0008094	ATP-dependent activity, acting on DNA	26/1274	210/18639	0.123809523809524	1.81137026239067	0.00238943552292258	0.0531527493874615
GO:0030295	protein kinase activator activity	19/1274	139/18639	0.136690647482014	1.99982494381261	0.00292715685099213	0.0638120193516285
GO:0019213	deacetylase activity	8/1274	37/18639	0.216216216216216	3.16330773473631	0.00302378026184573	0.0646258918708204
GO:0051082	unfolded protein binding	17/1274	121/18639	0.140495867768595	2.05549645160035	0.00355847563820199	0.0745911239546186
GO:0140693	molecular condensate scaffold activity	9/1274	48/18639	0.1875	2.74318092621664	0.00470296765962928	0.0967214103584135
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	4/1274	11/18639	0.363636363636364	5.32010846296561	0.00485761384121105	0.0980518349429638
GO:0140662	ATP-dependent protein folding chaperone	8/1274	40/18639	0.2	2.92605965463108	0.0050221326131846	0.099529537243113
GO:0001222	transcription corepressor binding	9/1274	49/18639	0.183673469387755	2.68719764200814	0.00541936645389231	0.102135278413016
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	11/1274	67/18639	0.164179104477612	2.40198926872701	0.00543472123665591	0.102135278413016
GO:0042054	histone methyltransferase activity	11/1274	67/18639	0.164179104477612	2.40198926872701	0.00543472123665591	0.102135278413016
GO:0042974	nuclear retinoic acid receptor binding	6/1274	25/18639	0.24	3.5112715855573	0.00578272423730917	0.106525634265023
GO:0019209	kinase activator activity	19/1274	148/18639	0.128378378378378	1.87821396749968	0.00586379638156091	0.106525634265023
GO:0008525	phosphatidylcholine transporter activity	5/1274	18/18639	0.277777777777778	4.06397174254317	0.00598609745272909	0.106883923389902
GO:0071889	14-3-3 protein binding	7/1274	33/18639	0.212121212121212	3.1033966033966	0.00607963600933387	0.106883923389902
GO:0016741	transferase activity, transferring one-carbon groups	25/1274	215/18639	0.116279069767442	1.70119747362272	0.00647415938511092	0.1112364749489
GO:0008168	methyltransferase activity	24/1274	204/18639	0.117647058823529	1.7212115615477	0.00653131596030237	0.1112364749489
GO:0016279	protein-lysine N-methyltransferase activity	11/1274	69/18639	0.159420289855072	2.3323663913726	0.00681230126100531	0.113887922092082
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/1274	12/18639	0.333333333333333	4.87676609105181	0.00689596592484164	0.113887922092082
GO:0008175	tRNA methyltransferase activity	7/1274	34/18639	0.205882352941176	3.01212023270847	0.00721342566529402	0.117352745898067
GO:0016278	lysine N-methyltransferase activity	11/1274	70/18639	0.157142857142857	2.29904687149585	0.00759629708137379	0.121764173804374
GO:0003697	single-stranded DNA binding	16/1274	121/18639	0.132231404958678	1.93458489562386	0.00826420199221067	0.130550437268256
GO:0019887	protein kinase regulator activity	28/1274	255/18639	0.109803921568627	1.60646412411118	0.00893015174102977	0.139055219967464
GO:0046974	histone H3K9 methyltransferase activity	4/1274	13/18639	0.307692307692308	4.50163023789397	0.0094284672842	0.140081061656093
GO:0140333	glycerophospholipid flippase activity	4/1274	13/18639	0.307692307692308	4.50163023789397	0.0094284672842	0.140081061656093
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/1274	13/18639	0.307692307692308	4.50163023789397	0.0094284672842	0.140081061656093
GO:0004386	helicase activity	19/1274	155/18639	0.12258064516129	1.7933914012255	0.00953134609011405	0.140081061656093
GO:0140939	histone H4 methyltransferase activity	5/1274	20/18639	0.25	3.65757456828885	0.00966574780294488	0.140081061656093
GO:0005543	phospholipid binding	48/1274	497/18639	0.096579476861167	1.41298655354419	0.00976711989528722	0.140081061656093
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	20/1274	167/18639	0.119760479041916	1.75213152971921	0.0102013543767066	0.144408782735197
GO:0140303	intramembrane lipid transporter activity	8/1274	45/18639	0.177777777777778	2.60094191522763	0.0104117512771051	0.145497549898007
GO:0140297	DNA-binding transcription factor binding	47/1274	488/18639	0.0963114754098361	1.40906561237357	0.0109885522735837	0.151614202255775
GO:0140789	histone phosphatase activity	17/1274	136/18639	0.125	1.82878728414443	0.0114071552164418	0.15542248982402
GO:0160215	deacylase activity	10/1274	65/18639	0.153846153846154	2.25081511894699	0.012325517898624	0.165152257255192
GO:0008276	protein methyltransferase activity	13/1274	95/18639	0.136842105263158	2.00204081632653	0.0124324333831194	0.165152257255192
GO:0015294	solute:monoatomic cation symporter activity	15/1274	116/18639	0.129310344827586	1.89184891463217	0.0125758140845697	0.165152257255192
GO:0001784	phosphotyrosine residue binding	8/1274	47/18639	0.170212765957447	2.49026353585624	0.0134697988761537	0.174786675892947
GO:0035591	signaling adaptor activity	16/1274	129/18639	0.124031007751938	1.8146106385309	0.0148226986507645	0.190079312109803
GO:0008173	RNA methyltransferase activity	10/1274	67/18639	0.149253731343284	2.18362660793364	0.0151069344994567	0.191471611679161
GO:0000774	adenyl-nucleotide exchange factor activity	4/1274	15/18639	0.266666666666667	3.90141287284144	0.0161344409800239	0.197601580541866
GO:0141050	histone H3K deacetylase activity	4/1274	15/18639	0.266666666666667	3.90141287284144	0.0161344409800239	0.197601580541866
GO:0141051	histone H4K deacetylase activity	4/1274	15/18639	0.266666666666667	3.90141287284144	0.0161344409800239	0.197601580541866
GO:0061775	cohesin loader activity	18/1274	153/18639	0.117647058823529	1.7212115615477	0.0169082930061467	0.204778215296666
GO:0060590	ATPase regulator activity	8/1274	49/18639	0.163265306122449	2.38862012622946	0.0171361014444471	0.205256599719202
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	12/1274	89/18639	0.134831460674157	1.97262448626815	0.0177744188928246	0.208323834335256
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	12/1274	89/18639	0.134831460674157	1.97262448626815	0.0177744188928246	0.208323834335256
GO:0070063	RNA polymerase binding	9/1274	59/18639	0.152542372881356	2.23174041454913	0.018043319190097	0.209225722523465
GO:0140793	histone H2AXY142 phosphatase activity	12/1274	90/18639	0.133333333333333	1.95070643642072	0.0192770180512777	0.221178417640976
GO:0042169	SH2 domain binding	7/1274	41/18639	0.170731707317073	2.49785580273385	0.0199193628652734	0.224298599890159
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	9/1274	60/18639	0.15	2.19454474097331	0.0199820084795683	0.224298599890159
GO:0004708	MAP kinase kinase activity	4/1274	16/18639	0.25	3.65757456828885	0.0203720746689227	0.224298599890159
GO:0140327	flippase activity	4/1274	16/18639	0.25	3.65757456828885	0.0203720746689227	0.224298599890159
GO:0003712	transcription coregulator activity	46/1274	495/18639	0.0929292929292929	1.35958327386899	0.0209919178558467	0.228811904628729
GO:0030544	Hsp70 protein binding	8/1274	51/18639	0.156862745098039	2.29494874873026	0.0214695160778932	0.230665546166671
GO:0001618	virus receptor activity	11/1274	81/18639	0.135802469135802	1.98683062968777	0.0215852162467894	0.230665546166671
GO:0003714	transcription corepressor activity	22/1274	204/18639	0.107843137254902	1.57777726475205	0.0227029745770708	0.238085089656986
GO:0140658	ATP-dependent chromatin remodeler activity	18/1274	158/18639	0.113924050632911	1.66674284124555	0.0227163755269051	0.238085089656986
GO:0140272	exogenous protein binding	11/1274	82/18639	0.134146341463415	1.96260098786231	0.0234445836087948	0.243377106034156
GO:0032183	SUMO binding	4/1274	17/18639	0.235294117647059	3.44242312309539	0.0252319481853576	0.249802485162857
GO:0046965	nuclear retinoid X receptor binding	4/1274	17/18639	0.235294117647059	3.44242312309539	0.0252319481853576	0.249802485162857
GO:0031625	ubiquitin protein ligase binding	30/1274	302/18639	0.0993377483443709	1.4533408880618	0.0253934302999784	0.249802485162857
GO:0005516	calmodulin binding	22/1274	207/18639	0.106280193236715	1.55491092758173	0.0262848701695408	0.249802485162857
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/1274	10/18639	0.3	4.38908948194663	0.0265844846595335	0.249802485162857
GO:0016427	tRNA (cytidine) methyltransferase activity	3/1274	10/18639	0.3	4.38908948194663	0.0265844846595335	0.249802485162857
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/1274	10/18639	0.3	4.38908948194663	0.0265844846595335	0.249802485162857
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/1274	10/18639	0.3	4.38908948194663	0.0265844846595335	0.249802485162857
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/1274	10/18639	0.3	4.38908948194663	0.0265844846595335	0.249802485162857
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/1274	10/18639	0.3	4.38908948194663	0.0265844846595335	0.249802485162857
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/1274	10/18639	0.3	4.38908948194663	0.0265844846595335	0.249802485162857
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	27/1274	268/18639	0.100746268656716	1.47394796035521	0.0279484937266059	0.260374856085474
GO:0000510	H3-H4 histone complex chaperone activity	17/1274	151/18639	0.112582781456954	1.6471196731367	0.0290762428999103	0.261926485627291
GO:0140584	chromatin extrusion motor activity	17/1274	151/18639	0.112582781456954	1.6471196731367	0.0290762428999103	0.261926485627291
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	17/1274	151/18639	0.112582781456954	1.6471196731367	0.0290762428999103	0.261926485627291
GO:0140849	ATP-dependent H2AZ histone chaperone activity	17/1274	151/18639	0.112582781456954	1.6471196731367	0.0290762428999103	0.261926485627291
GO:0004721	phosphoprotein phosphatase activity	19/1274	175/18639	0.108571428571429	1.58843238394259	0.0306007395787996	0.268286771567001
GO:0015616	DNA translocase activity	17/1274	152/18639	0.111842105263158	1.63628335949765	0.0307355315930795	0.268286771567001
GO:0140674	ATP-dependent histone chaperone activity	17/1274	152/18639	0.111842105263158	1.63628335949765	0.0307355315930795	0.268286771567001
GO:0003725	double-stranded RNA binding	10/1274	75/18639	0.133333333333333	1.95070643642072	0.0310129662545341	0.268286771567001
GO:0044183	protein folding chaperone	10/1274	75/18639	0.133333333333333	1.95070643642072	0.0310129662545341	0.268286771567001
GO:0004715	non-membrane spanning protein tyrosine kinase activity	7/1274	45/18639	0.155555555555556	2.27582417582418	0.0317909614175174	0.272851558622788
GO:0031072	heat shock protein binding	15/1274	131/18639	0.114503816793893	1.6752249931094	0.0339916811870154	0.288128321949259
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/1274	11/18639	0.272727272727273	3.9900813472242	0.0347320612164044	0.288128321949259
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/1274	11/18639	0.272727272727273	3.9900813472242	0.0347320612164044	0.288128321949259
GO:0004725	protein tyrosine phosphatase activity	12/1274	98/18639	0.122448979591837	1.79146509467209	0.0348926041259653	0.288128321949259
GO:0008170	N-methyltransferase activity	12/1274	98/18639	0.122448979591837	1.79146509467209	0.0348926041259653	0.288128321949259
GO:0019207	kinase regulator activity	28/1274	287/18639	0.0975609756097561	1.42734617299077	0.0365992753038438	0.295576743910612
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	33/1274	349/18639	0.0945558739255014	1.38338063900896	0.0366701640023058	0.295576743910612
GO:0046624	sphingolipid transporter activity	4/1274	19/18639	0.210526315789474	3.08006279434851	0.0368793001576544	0.295576743910612
GO:0050145	nucleoside monophosphate kinase activity	4/1274	19/18639	0.210526315789474	3.08006279434851	0.0368793001576544	0.295576743910612
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	5/1274	28/18639	0.178571428571429	2.61255326306347	0.0390376064559055	0.305190293184441
GO:0097718	disordered domain specific binding	5/1274	28/18639	0.178571428571429	2.61255326306347	0.0390376064559055	0.305190293184441
GO:0061749	forked DNA-dependent helicase activity	7/1274	47/18639	0.148936170212766	2.17898059387421	0.0391987532530474	0.305190293184441
GO:1990518	single-stranded 3'-5' DNA helicase activity	7/1274	47/18639	0.148936170212766	2.17898059387421	0.0391987532530474	0.305190293184441
GO:0005548	phospholipid transporter activity	9/1274	68/18639	0.132352941176471	1.93636300674116	0.0411671627790141	0.311504727371094
GO:0015293	symporter activity	16/1274	146/18639	0.10958904109589	1.60332035870196	0.0414157282227586	0.311504727371094
GO:0001217	DNA-binding transcription repressor activity	27/1274	278/18639	0.0971223021582734	1.42092824955107	0.0414508860533642	0.311504727371094
GO:0042162	telomeric DNA binding	6/1274	38/18639	0.157894736842105	2.31004709576138	0.0424834833913515	0.311504727371094
GO:0009378	four-way junction helicase activity	7/1274	48/18639	0.145833333333333	2.13358516483516	0.043292146349026	0.311504727371094
GO:0016879	ligase activity, forming carbon-nitrogen bonds	7/1274	48/18639	0.145833333333333	2.13358516483516	0.043292146349026	0.311504727371094
GO:0036121	double-stranded DNA helicase activity	7/1274	48/18639	0.145833333333333	2.13358516483516	0.043292146349026	0.311504727371094
GO:0043138	3'-5' DNA helicase activity	7/1274	48/18639	0.145833333333333	2.13358516483516	0.043292146349026	0.311504727371094
GO:0031418	L-ascorbic acid binding	4/1274	20/18639	0.2	2.92605965463108	0.0436826882463317	0.311504727371094
GO:0140664	ATP-dependent DNA damage sensor activity	4/1274	20/18639	0.2	2.92605965463108	0.0436826882463317	0.311504727371094
GO:0003995	acyl-CoA dehydrogenase activity	3/1274	12/18639	0.25	3.65757456828885	0.0440107596469253	0.311504727371094
GO:0031543	peptidyl-proline dioxygenase activity	3/1274	12/18639	0.25	3.65757456828885	0.0440107596469253	0.311504727371094
GO:0034452	dynactin binding	3/1274	12/18639	0.25	3.65757456828885	0.0440107596469253	0.311504727371094
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/1274	12/18639	0.25	3.65757456828885	0.0440107596469253	0.311504727371094
GO:0001786	phosphatidylserine binding	8/1274	59/18639	0.135593220338983	1.98376925737701	0.0464958049708071	0.321611017225126
GO:0031593	polyubiquitin modification-dependent protein binding	8/1274	59/18639	0.135593220338983	1.98376925737701	0.0464958049708071	0.321611017225126
GO:0045309	protein phosphorylated amino acid binding	8/1274	59/18639	0.135593220338983	1.98376925737701	0.0464958049708071	0.321611017225126
GO:0003689	DNA clamp loader activity	17/1274	160/18639	0.10625	1.55446919152276	0.0466188446986881	0.321611017225126
GO:0016776	phosphotransferase activity, phosphate group as acceptor	6/1274	39/18639	0.153846153846154	2.25081511894699	0.0474197620870494	0.323783541218109
GO:0016922	nuclear receptor binding	15/1274	137/18639	0.109489051094891	1.601857475163	0.0475278592613738	0.323783541218109
GO:0097110	scaffold protein binding	9/1274	70/18639	0.128571428571429	1.8810383494057	0.0482035063241245	0.326346719834135
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/1274	21/18639	0.19047619047619	2.78672348060103	0.0511407232043262	0.339898709101924
GO:0008373	sialyltransferase activity	4/1274	21/18639	0.19047619047619	2.78672348060103	0.0511407232043262	0.339898709101924
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/1274	21/18639	0.19047619047619	2.78672348060103	0.0511407232043262	0.339898709101924
GO:0051213	dioxygenase activity	11/1274	93/18639	0.118279569892473	1.73046538714741	0.0521391304987918	0.343824247386282
GO:0044389	ubiquitin-like protein ligase binding	30/1274	322/18639	0.093167701863354	1.36307126768529	0.0523622248313053	0.343824247386282
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/1274	13/18639	0.230769230769231	3.37622267842048	0.0543854473557428	0.345350674885286
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/1274	13/18639	0.230769230769231	3.37622267842048	0.0543854473557428	0.345350674885286
GO:0140098	catalytic activity, acting on RNA	35/1274	387/18639	0.0904392764857881	1.32315359059545	0.0550216216169527	0.345350674885286
GO:0140713	histone chaperone activity	17/1274	164/18639	0.103658536585366	1.5165553088027	0.0564383335223758	0.345350674885286
GO:0070273	phosphatidylinositol-4-phosphate binding	5/1274	31/18639	0.161290322580645	2.35972552792829	0.0571138909344384	0.345350674885286
GO:0015291	secondary active transmembrane transporter activity	27/1274	287/18639	0.0940766550522648	1.37636952395539	0.0572855299384326	0.345350674885286
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0016881	acid-amino acid ligase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0032931	histone H3K56 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0043992	histone H3K9 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0043993	histone H3K18 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0043994	histone H3K23 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0043999	histone H2AK5 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0044012	histone H2AK9 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0044014	histone H2BK5 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0044015	histone H2BK12 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0044016	histone H3K4 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0044017	histone H3K27 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0044018	histone H3K36 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0046972	histone H4K16 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0140908	histone H3K122 acetyltransferase activity	4/1274	22/18639	0.181818181818182	2.6600542314828	0.059248235049127	0.345350674885286
GO:0043539	protein serine/threonine kinase activator activity	9/1274	73/18639	0.123287671232877	1.80373540353971	0.0601749003215288	0.348886390162055
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	14/1274	130/18639	0.107692307692308	1.57557058326289	0.0606778393846164	0.349940978461544
GO:0019902	phosphatase binding	19/1274	190/18639	0.1	1.46302982731554	0.0614068861432043	0.352281609979435
GO:0015106	bicarbonate transmembrane transporter activity	5/1274	32/18639	0.15625	2.28598410518053	0.0640439721706465	0.358989694292505
GO:0051059	NF-kappaB binding	5/1274	32/18639	0.15625	2.28598410518053	0.0640439721706465	0.358989694292505
GO:0004520	DNA endonuclease activity	6/1274	42/18639	0.142857142857143	2.09004261045077	0.0642777497357252	0.358989694292505
GO:0019894	kinesin binding	6/1274	42/18639	0.142857142857143	2.09004261045077	0.0642777497357252	0.358989694292505
GO:0043175	RNA polymerase core enzyme binding	6/1274	42/18639	0.142857142857143	2.09004261045077	0.0642777497357252	0.358989694292505
GO:0003678	DNA helicase activity	9/1274	74/18639	0.121621621621622	1.77936060078917	0.0645522753039734	0.358989694292505
GO:0032454	histone H3K9 demethylase activity	3/1274	14/18639	0.214285714285714	3.13506391567616	0.0658097768239587	0.362286145141995
GO:0034236	protein kinase A catalytic subunit binding	3/1274	14/18639	0.214285714285714	3.13506391567616	0.0658097768239587	0.362286145141995
GO:0008171	O-methyltransferase activity	4/1274	23/18639	0.173913043478261	2.5443996996792	0.0679954812711107	0.369892036993288
GO:0044013	histone H2B acetyltransferase activity	4/1274	23/18639	0.173913043478261	2.5443996996792	0.0679954812711107	0.369892036993288
GO:0016757	glycosyltransferase activity	25/1274	267/18639	0.0936329588014981	1.36987811546399	0.068209449023533	0.369892036993288
GO:0004536	DNA nuclease activity	8/1274	64/18639	0.125	1.82878728414443	0.0691540465039481	0.373157973709423
GO:0030296	protein tyrosine kinase activator activity	5/1274	33/18639	0.151515151515152	2.216711859569	0.0714239135735518	0.383507713276707
GO:0051287	NAD binding	7/1274	54/18639	0.12962962962963	1.89652014652015	0.0735418461941882	0.392944178194437
GO:0051087	protein-folding chaperone binding	14/1274	134/18639	0.104477611940299	1.52853862555355	0.0741171502925356	0.394086311311531
GO:1902936	phosphatidylinositol bisphosphate binding	12/1274	111/18639	0.108108108108108	1.58165386736815	0.0764883399431937	0.394764748868459
GO:0019205	nucleobase-containing compound kinase activity	6/1274	44/18639	0.136363636363636	1.9950406736121	0.0772354587662815	0.394764748868459
GO:0035035	histone acetyltransferase binding	4/1274	24/18639	0.166666666666667	2.4383830455259	0.0773685578134135	0.394764748868459
GO:0043998	histone H2A acetyltransferase activity	4/1274	24/18639	0.166666666666667	2.4383830455259	0.0773685578134135	0.394764748868459
GO:0070300	phosphatidic acid binding	4/1274	24/18639	0.166666666666667	2.4383830455259	0.0773685578134135	0.394764748868459
GO:0140612	DNA damage sensor activity	4/1274	24/18639	0.166666666666667	2.4383830455259	0.0773685578134135	0.394764748868459
GO:0004089	carbonate dehydratase activity	3/1274	15/18639	0.2	2.92605965463108	0.0782286107849423	0.394764748868459
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/1274	15/18639	0.2	2.92605965463108	0.0782286107849423	0.394764748868459
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/1274	15/18639	0.2	2.92605965463108	0.0782286107849423	0.394764748868459
GO:0010181	FMN binding	3/1274	15/18639	0.2	2.92605965463108	0.0782286107849423	0.394764748868459
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/1274	15/18639	0.2	2.92605965463108	0.0782286107849423	0.394764748868459
GO:0000030	mannosyltransferase activity	4/1274	25/18639	0.16	2.34084772370487	0.0873498179416505	0.436749089708252
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	4/1274	25/18639	0.16	2.34084772370487	0.0873498179416505	0.436749089708252
GO:0046332	SMAD binding	9/1274	79/18639	0.113924050632911	1.66674284124555	0.0893971487613137	0.444944713012931
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/1274	16/18639	0.1875	2.74318092621664	0.0915801191194083	0.449650134415113
GO:0022858	alanine transmembrane transporter activity	3/1274	16/18639	0.1875	2.74318092621664	0.0915801191194083	0.449650134415113
GO:0030275	LRR domain binding	3/1274	16/18639	0.1875	2.74318092621664	0.0915801191194083	0.449650134415113
GO:0140597	protein carrier chaperone	18/1274	188/18639	0.0957446808510638	1.40077323891914	0.0926958893143573	0.45308753072937
GO:0140101	catalytic activity, acting on a tRNA	14/1274	139/18639	0.100719424460432	1.47355522175666	0.0934592901989327	0.454779581771592
GO:0000993	RNA polymerase II complex binding	5/1274	36/18639	0.138888888888889	2.03198587127159	0.0962059794708848	0.466064522770064
GO:0004713	protein tyrosine kinase activity	14/1274	140/18639	0.1	1.46302982731554	0.0976714593251658	0.471070312674472
GO:0017116	single-stranded DNA helicase activity	7/1274	58/18639	0.120689655172414	1.76572565365669	0.0992162404109595	0.476412784352184
GO:0015101	organic cation transmembrane transporter activity	9/1274	81/18639	0.111111111111111	1.62558869701727	0.100719213691238	0.481508521594075
GO:0005319	lipid transporter activity	17/1274	178/18639	0.0955056179775281	1.39727567777327	0.101744344114323	0.484285306046343
GO:0051219	phosphoprotein binding	10/1274	93/18639	0.10752688172043	1.5731503519522	0.102489387237123	0.485710574297669
GO:0004659	prenyltransferase activity	3/1274	17/18639	0.176470588235294	2.58181734232154	0.105797584319562	0.488641385204757
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/1274	17/18639	0.176470588235294	2.58181734232154	0.105797584319562	0.488641385204757
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/1274	17/18639	0.176470588235294	2.58181734232154	0.105797584319562	0.488641385204757
GO:0016805	dipeptidase activity	3/1274	17/18639	0.176470588235294	2.58181734232154	0.105797584319562	0.488641385204757
GO:0019198	transmembrane receptor protein phosphatase activity	3/1274	17/18639	0.176470588235294	2.58181734232154	0.105797584319562	0.488641385204757
GO:0070403	NAD+ binding	3/1274	17/18639	0.176470588235294	2.58181734232154	0.105797584319562	0.488641385204757
GO:0000287	magnesium ion binding	21/1274	230/18639	0.091304347826087	1.33580984233158	0.107500569262136	0.492728530771215
GO:0016874	ligase activity	16/1274	167/18639	0.0958083832335329	1.40170522377537	0.107586596627109	0.492728530771215
GO:0001671	ATPase activator activity	4/1274	27/18639	0.148148148148148	2.16745159602302	0.109050096974549	0.497341446452965
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	7/1274	60/18639	0.116666666666667	1.70686813186813	0.113674893815012	0.516273476076515
GO:0016763	pentosyltransferase activity	6/1274	49/18639	0.122448979591837	1.79146509467209	0.115517494576706	0.52030607061409
GO:0035254	glutamate receptor binding	6/1274	49/18639	0.122448979591837	1.79146509467209	0.115517494576706	0.52030607061409
GO:0042578	phosphoric ester hydrolase activity	31/1274	363/18639	0.0853994490358127	1.24941941175707	0.118021613150799	0.528851140665307
GO:0036408	histone H3K14 acetyltransferase activity	4/1274	28/18639	0.142857142857143	2.09004261045077	0.120718845394323	0.528851140665307
GO:0046966	nuclear thyroid hormone receptor binding	4/1274	28/18639	0.142857142857143	2.09004261045077	0.120718845394323	0.528851140665307
GO:0051959	dynein light intermediate chain binding	4/1274	28/18639	0.142857142857143	2.09004261045077	0.120718845394323	0.528851140665307
GO:0000400	four-way junction DNA binding	3/1274	18/18639	0.166666666666667	2.4383830455259	0.120810948647396	0.528851140665307
GO:0015280	ligand-gated sodium channel activity	3/1274	18/18639	0.166666666666667	2.4383830455259	0.120810948647396	0.528851140665307
GO:1901611	phosphatidylglycerol binding	3/1274	18/18639	0.166666666666667	2.4383830455259	0.120810948647396	0.528851140665307
GO:0016836	hydro-lyase activity	7/1274	61/18639	0.114754098360656	1.67888668708341	0.121296716580665	0.528853684291697
GO:0016791	phosphatase activity	24/1274	273/18639	0.0879120879120879	1.28618006796971	0.123002666495611	0.534155005897277
GO:0032813	tumor necrosis factor receptor superfamily binding	6/1274	50/18639	0.12	1.75563579277865	0.124140715617053	0.536954541186845
GO:0004518	nuclease activity	19/1274	209/18639	0.0909090909090909	1.3300271157414	0.124632567816763	0.536954541186845
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	12/1274	122/18639	0.0983606557377049	1.43904573178578	0.129475191071849	0.555621882946125
GO:0140104	molecular carrier activity	22/1274	249/18639	0.0883534136546185	1.29263679521855	0.130134970242388	0.556263206134128
GO:0010484	histone H3 acetyltransferase activity	4/1274	29/18639	0.137931034482759	2.01797217560764	0.132896025465732	0.560004119883607
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/1274	29/18639	0.137931034482759	2.01797217560764	0.132896025465732	0.560004119883607
GO:0016830	carbon-carbon lyase activity	6/1274	51/18639	0.117647058823529	1.7212115615477	0.133068505148487	0.560004119883607
GO:0030331	nuclear estrogen receptor binding	5/1274	40/18639	0.125	1.82878728414443	0.135048129718872	0.560004119883607
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	5/1274	40/18639	0.125	1.82878728414443	0.135048129718872	0.560004119883607
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/1274	19/18639	0.157894736842105	2.31004709576138	0.136548132739222	0.560004119883607
GO:0042800	histone H3K4 methyltransferase activity	3/1274	19/18639	0.157894736842105	2.31004709576138	0.136548132739222	0.560004119883607
GO:0140036	ubiquitin-modified protein reader activity	3/1274	19/18639	0.157894736842105	2.31004709576138	0.136548132739222	0.560004119883607
GO:0016829	lyase activity	18/1274	200/18639	0.09	1.31672684458399	0.141072632453838	0.560004119883607
GO:0005080	protein kinase C binding	6/1274	52/18639	0.115384615384615	1.68811133921024	0.142291490348039	0.560004119883607
GO:0030159	signaling receptor complex adaptor activity	6/1274	52/18639	0.115384615384615	1.68811133921024	0.142291490348039	0.560004119883607
GO:0001965	G-protein alpha-subunit binding	4/1274	30/18639	0.133333333333333	1.95070643642072	0.145551373646421	0.560004119883607
GO:0043995	histone H4K5 acetyltransferase activity	4/1274	30/18639	0.133333333333333	1.95070643642072	0.145551373646421	0.560004119883607
GO:0043996	histone H4K8 acetyltransferase activity	4/1274	30/18639	0.133333333333333	1.95070643642072	0.145551373646421	0.560004119883607
GO:0043997	histone H4K12 acetyltransferase activity	4/1274	30/18639	0.133333333333333	1.95070643642072	0.145551373646421	0.560004119883607
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	5/1274	41/18639	0.121951219512195	1.78418271623847	0.145705535859825	0.560004119883607
GO:0017080	sodium channel regulator activity	5/1274	41/18639	0.121951219512195	1.78418271623847	0.145705535859825	0.560004119883607
GO:0042287	MHC protein binding	5/1274	41/18639	0.121951219512195	1.78418271623847	0.145705535859825	0.560004119883607
GO:0005522	profilin binding	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:0008140	cAMP response element binding protein binding	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:0015187	glycine transmembrane transporter activity	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:0030957	Tat protein binding	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:0051864	histone H3K36 demethylase activity	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:0051880	G-quadruplex DNA binding	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:0070513	death domain binding	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:0140940	histone H2A methyltransferase activity	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:1905394	retromer complex binding	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:1990259	histone H2AQ104 methyltransferase activity	2/1274	10/18639	0.2	2.92605965463108	0.145909330318298	0.560004119883607
GO:0051018	protein kinase A binding	6/1274	53/18639	0.113207547169811	1.65626018186665	0.151799519632857	0.575100702550825
GO:0016505	peptidase activator activity involved in apoptotic process	3/1274	20/18639	0.15	2.19454474097331	0.152936152355615	0.575100702550825
GO:0042288	MHC class I protein binding	3/1274	20/18639	0.15	2.19454474097331	0.152936152355615	0.575100702550825
GO:0043024	ribosomal small subunit binding	3/1274	20/18639	0.15	2.19454474097331	0.152936152355615	0.575100702550825
GO:0015081	sodium ion transmembrane transporter activity	15/1274	164/18639	0.0914634146341463	1.33813703717885	0.152984693575473	0.575100702550825
GO:0003727	single-stranded RNA binding	9/1274	89/18639	0.101123595505618	1.47946836470111	0.153655195060775	0.575100702550825
GO:0043021	ribonucleoprotein complex binding	16/1274	177/18639	0.0903954802259887	1.32251283825134	0.154020658897493	0.575100702550825
GO:0003724	RNA helicase activity	8/1274	77/18639	0.103896103896104	1.52003098941874	0.154621734180872	0.575100702550825
GO:0008307	structural constituent of muscle	5/1274	42/18639	0.119047619047619	1.74170217537564	0.156709290741461	0.575100702550825
GO:0003713	transcription coactivator activity	22/1274	256/18639	0.0859375	1.25729125784929	0.158660082533226	0.575100702550825
GO:0004519	endonuclease activity	12/1274	127/18639	0.094488188976378	1.38239038801469	0.158938342517126	0.575100702550825
GO:0019783	ubiquitin-like protein peptidase activity	12/1274	127/18639	0.094488188976378	1.38239038801469	0.158938342517126	0.575100702550825
GO:0003779	actin binding	36/1274	443/18639	0.0812641083521445	1.18891814409389	0.159618677867487	0.575100702550825
GO:0022804	active transmembrane transporter activity	37/1274	457/18639	0.0809628008752735	1.18450992583534	0.161228958427616	0.575100702550825
GO:0017069	snRNA binding	6/1274	54/18639	0.111111111111111	1.62558869701727	0.16158172881269	0.575100702550825
GO:0050661	NADP binding	6/1274	54/18639	0.111111111111111	1.62558869701727	0.16158172881269	0.575100702550825
GO:0017124	SH3 domain binding	11/1274	115/18639	0.0956521739130435	1.39941983482356	0.162482536624054	0.575100702550825
GO:0035401	histone H3Y41 kinase activity	11/1274	115/18639	0.0956521739130435	1.39941983482356	0.162482536624054	0.575100702550825
GO:0101005	deubiquitinase activity	11/1274	115/18639	0.0956521739130435	1.39941983482356	0.162482536624054	0.575100702550825
GO:0140801	histone H2AXY142 kinase activity	11/1274	115/18639	0.0956521739130435	1.39941983482356	0.162482536624054	0.575100702550825
GO:0004722	protein serine/threonine phosphatase activity	10/1274	103/18639	0.0970873786407767	1.42041730807334	0.16578484652378	0.575100702550825
GO:0048156	tau protein binding	5/1274	43/18639	0.116279069767442	1.70119747362272	0.16804143643663	0.575100702550825
GO:0072341	modified amino acid binding	9/1274	91/18639	0.0989010989010989	1.44695257646592	0.168688428100698	0.575100702550825
GO:0005123	death receptor binding	3/1274	21/18639	0.142857142857143	2.09004261045077	0.169902057214163	0.575100702550825
GO:0019200	carbohydrate kinase activity	3/1274	21/18639	0.142857142857143	2.09004261045077	0.169902057214163	0.575100702550825
GO:0070182	DNA polymerase binding	3/1274	21/18639	0.142857142857143	2.09004261045077	0.169902057214163	0.575100702550825
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0005225	volume-sensitive anion channel activity	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0008526	phosphatidylinositol transfer activity	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0019206	nucleoside kinase activity	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0042608	T cell receptor binding	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0043522	leucine zipper domain binding	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0097493	structural molecule activity conferring elasticity	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0140031	phosphorylation-dependent protein binding	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0180030	inositol phosphate kinase activity	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:1990948	ubiquitin ligase inhibitor activity	2/1274	11/18639	0.181818181818182	2.6600542314828	0.170615390118718	0.575100702550825
GO:0008186	ATP-dependent activity, acting on RNA	8/1274	79/18639	0.10126582278481	1.48154919221827	0.170947364794924	0.575100702550825
GO:0015370	solute:sodium symporter activity	8/1274	79/18639	0.10126582278481	1.48154919221827	0.170947364794924	0.575100702550825
GO:0016835	carbon-oxygen lyase activity	8/1274	79/18639	0.10126582278481	1.48154919221827	0.170947364794924	0.575100702550825
GO:0043178	alcohol binding	9/1274	92/18639	0.0978260869565217	1.43122483106955	0.176453698253472	0.591798557219336
GO:0001216	DNA-binding transcription activator activity	39/1274	491/18639	0.0794297352342159	1.16208071823434	0.183878048509932	0.597542252610786
GO:0019903	protein phosphatase binding	13/1274	144/18639	0.0902777777777778	1.32079081632653	0.185839301626864	0.597542252610786
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/1274	33/18639	0.121212121212121	1.7733694876552	0.186064680757141	0.597542252610786
GO:0015377	chloride:monoatomic cation symporter activity	3/1274	22/18639	0.136363636363636	1.9950406736121	0.187373713345484	0.597542252610786
GO:0050321	tau-protein kinase activity	3/1274	22/18639	0.136363636363636	1.9950406736121	0.187373713345484	0.597542252610786
GO:0140035	ubiquitin-like protein reader activity	3/1274	22/18639	0.136363636363636	1.9950406736121	0.187373713345484	0.597542252610786
GO:0033192	calmodulin-dependent protein phosphatase activity	8/1274	81/18639	0.0987654320987654	1.44496773068202	0.188011931989541	0.597542252610786
GO:0140791	histone H2AXS140 phosphatase activity	8/1274	81/18639	0.0987654320987654	1.44496773068202	0.188011931989541	0.597542252610786
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	8/1274	81/18639	0.0987654320987654	1.44496773068202	0.188011931989541	0.597542252610786
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	8/1274	81/18639	0.0987654320987654	1.44496773068202	0.188011931989541	0.597542252610786
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	8/1274	81/18639	0.0987654320987654	1.44496773068202	0.188011931989541	0.597542252610786
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	8/1274	81/18639	0.0987654320987654	1.44496773068202	0.188011931989541	0.597542252610786
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	8/1274	81/18639	0.0987654320987654	1.44496773068202	0.188011931989541	0.597542252610786
GO:1990439	MAP kinase serine/threonine phosphatase activity	8/1274	81/18639	0.0987654320987654	1.44496773068202	0.188011931989541	0.597542252610786
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	12/1274	132/18639	0.0909090909090909	1.3300271157414	0.191497626984932	0.597542252610786
GO:0015932	nucleobase-containing compound transmembrane transporter activity	6/1274	57/18639	0.105263157894737	1.54003139717425	0.192455510458745	0.597542252610786
GO:0004126	cytidine deaminase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0005436	sodium:phosphate symporter activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0016273	arginine N-methyltransferase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0016274	protein-arginine N-methyltransferase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0016423	tRNA (guanine) methyltransferase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0036009	protein-glutamine N-methyltransferase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0043047	single-stranded telomeric DNA binding	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0045295	gamma-catenin binding	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0070679	inositol 1,4,5 trisphosphate binding	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0097371	MDM2/MDM4 family protein binding	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/1274	12/18639	0.166666666666667	2.4383830455259	0.195936316213077	0.597542252610786
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	8/1274	82/18639	0.0975609756097561	1.42734617299077	0.196805200630525	0.597542252610786
GO:0033549	MAP kinase phosphatase activity	8/1274	82/18639	0.0975609756097561	1.42734617299077	0.196805200630525	0.597542252610786
GO:0004843	cysteine-type deubiquitinase activity	10/1274	108/18639	0.0925925925925926	1.35465724751439	0.203156426392332	0.606167522866022
GO:0030276	clathrin binding	5/1274	46/18639	0.108695652173913	1.5902498122995	0.203817623883949	0.606167522866022
GO:0030291	protein serine/threonine kinase inhibitor activity	5/1274	46/18639	0.108695652173913	1.5902498122995	0.203817623883949	0.606167522866022
GO:0140030	modification-dependent protein binding	15/1274	173/18639	0.0867052023121387	1.26852297166087	0.204545084647078	0.606167522866022
GO:0003887	DNA-directed DNA polymerase activity	3/1274	23/18639	0.130434782608696	1.9082997747594	0.20528044815664	0.606167522866022
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/1274	23/18639	0.130434782608696	1.9082997747594	0.20528044815664	0.606167522866022
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/1274	23/18639	0.130434782608696	1.9082997747594	0.20528044815664	0.606167522866022
GO:0005283	amino acid:sodium symporter activity	3/1274	23/18639	0.130434782608696	1.9082997747594	0.20528044815664	0.606167522866022
GO:0140103	catalytic activity, acting on a glycoprotein	3/1274	23/18639	0.130434782608696	1.9082997747594	0.20528044815664	0.606167522866022
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/1274	23/18639	0.130434782608696	1.9082997747594	0.20528044815664	0.606167522866022
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	8/1274	83/18639	0.0963855421686747	1.41014923114751	0.205763287578375	0.606167522866022
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	38/1274	484/18639	0.0785123966942149	1.14865978177666	0.2074371291818	0.609451403795586
GO:0015297	antiporter activity	12/1274	135/18639	0.0888888888888889	1.30047095761381	0.212391123538214	0.621268183369205
GO:0005343	organic acid:sodium symporter activity	4/1274	35/18639	0.114285714285714	1.67203408836062	0.214860861337916	0.621268183369205
GO:0010485	histone H4 acetyltransferase activity	4/1274	35/18639	0.114285714285714	1.67203408836062	0.214860861337916	0.621268183369205
GO:0140566	histone reader activity	4/1274	35/18639	0.114285714285714	1.67203408836062	0.214860861337916	0.621268183369205
GO:0004527	exonuclease activity	8/1274	84/18639	0.0952380952380952	1.39336174030052	0.214878995532285	0.621268183369205
GO:0017018	myosin phosphatase activity	8/1274	84/18639	0.0952380952380952	1.39336174030052	0.214878995532285	0.621268183369205
GO:0140359	ABC-type transporter activity	5/1274	47/18639	0.106382978723404	1.55641470991015	0.216269963856867	0.622740704194887
GO:0004465	lipoprotein lipase activity	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0008035	high-density lipoprotein particle binding	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0008253	5'-nucleotidase activity	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0035325	Toll-like receptor binding	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0035673	oligopeptide transmembrane transporter activity	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0061459	L-arginine transmembrane transporter activity	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0071837	HMG box domain binding	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0140852	histone ubiquitin ligase activity	2/1274	13/18639	0.153846153846154	2.25081511894699	0.221672837823501	0.622740704194887
GO:0004806	triacylglycerol lipase activity	3/1274	24/18639	0.125	1.82878728414443	0.22355357534853	0.624803582384352
GO:0015295	solute:proton symporter activity	3/1274	24/18639	0.125	1.82878728414443	0.22355357534853	0.624803582384352
GO:0001098	basal transcription machinery binding	6/1274	60/18639	0.1	1.46302982731554	0.225351427855274	0.626614939699613
GO:0001099	basal RNA polymerase II transcription machinery binding	6/1274	60/18639	0.1	1.46302982731554	0.225351427855274	0.626614939699613
GO:0032266	phosphatidylinositol-3-phosphate binding	5/1274	48/18639	0.104166666666667	1.52398940345369	0.228951660675067	0.6350058782082
GO:0008483	transaminase activity	3/1274	25/18639	0.12	1.75563579277865	0.242126814994922	0.661614009744771
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/1274	25/18639	0.12	1.75563579277865	0.242126814994922	0.661614009744771
GO:0120020	cholesterol transfer activity	3/1274	25/18639	0.12	1.75563579277865	0.242126814994922	0.661614009744771
GO:0051020	GTPase binding	25/1274	315/18639	0.0793650793650794	1.16113478358376	0.246332429228172	0.661614009744771
GO:0042393	histone binding	20/1274	247/18639	0.0809716599190283	1.18463953628789	0.246876701734403	0.661614009744771
GO:0005545	1-phosphatidylinositol binding	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0008559	ABC-type xenobiotic transporter activity	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0015386	potassium:proton antiporter activity	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0019763	immunoglobulin receptor activity	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0019992	diacylglycerol binding	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0030983	mismatched DNA binding	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0070742	C2H2 zinc finger domain binding	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0071933	Arp2/3 complex binding	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0098847	sequence-specific single stranded DNA binding	2/1274	14/18639	0.142857142857143	2.09004261045077	0.247650014656758	0.661614009744771
GO:0042826	histone deacetylase binding	11/1274	127/18639	0.0866141732283465	1.26719118901346	0.25088300870094	0.668612419276343
GO:0004197	cysteine-type endopeptidase activity	8/1274	88/18639	0.0909090909090909	1.3300271157414	0.252766691576869	0.671989497118992
GO:0015605	organophosphate ester transmembrane transporter activity	5/1274	50/18639	0.1	1.46302982731554	0.254919816956558	0.676064721368975
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	11/1274	128/18639	0.0859375	1.25729125784929	0.258937608081638	0.678808874585095
GO:0000146	microfilament motor activity	4/1274	38/18639	0.105263157894737	1.54003139717425	0.260054084131796	0.678808874585095
GO:0043531	ADP binding	4/1274	38/18639	0.105263157894737	1.54003139717425	0.260054084131796	0.678808874585095
GO:0001221	transcription coregulator binding	10/1274	115/18639	0.0869565217391304	1.2721998498396	0.260697933735521	0.678808874585095
GO:0004435	phosphatidylinositol phospholipase C activity	3/1274	26/18639	0.115384615384615	1.68811133921024	0.260936622432252	0.678808874585095
GO:0034237	protein kinase A regulatory subunit binding	3/1274	26/18639	0.115384615384615	1.68811133921024	0.260936622432252	0.678808874585095
GO:0050750	low-density lipoprotein particle receptor binding	3/1274	26/18639	0.115384615384615	1.68811133921024	0.260936622432252	0.678808874585095
GO:0052742	phosphatidylinositol kinase activity	3/1274	26/18639	0.115384615384615	1.68811133921024	0.260936622432252	0.678808874585095
GO:0016758	hexosyltransferase activity	16/1274	197/18639	0.0812182741116751	1.1882475754847	0.272862452227525	0.701998075679065
GO:0008252	nucleotidase activity	2/1274	15/18639	0.133333333333333	1.95070643642072	0.273714846021654	0.701998075679065
GO:0017081	chloride channel regulator activity	2/1274	15/18639	0.133333333333333	1.95070643642072	0.273714846021654	0.701998075679065
GO:0048531	beta-1,3-galactosyltransferase activity	2/1274	15/18639	0.133333333333333	1.95070643642072	0.273714846021654	0.701998075679065
GO:0140161	monocarboxylate:sodium symporter activity	2/1274	15/18639	0.133333333333333	1.95070643642072	0.273714846021654	0.701998075679065
GO:0140776	protein-containing complex destabilizing activity	2/1274	15/18639	0.133333333333333	1.95070643642072	0.273714846021654	0.701998075679065
GO:0000217	DNA secondary structure binding	4/1274	39/18639	0.102564102564103	1.50054341263132	0.275516938485831	0.703310217680458
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/1274	39/18639	0.102564102564103	1.50054341263132	0.275516938485831	0.703310217680458
GO:0005385	zinc ion transmembrane transporter activity	3/1274	27/18639	0.111111111111111	1.62558869701727	0.279922438114465	0.709570831499459
GO:0016405	CoA-ligase activity	3/1274	27/18639	0.111111111111111	1.62558869701727	0.279922438114465	0.709570831499459
GO:0035255	ionotropic glutamate receptor binding	3/1274	27/18639	0.111111111111111	1.62558869701727	0.279922438114465	0.709570831499459
GO:0120013	lipid transfer activity	6/1274	65/18639	0.0923076923076923	1.35048907136819	0.283660698843164	0.717378565519834
GO:0052689	carboxylic ester hydrolase activity	8/1274	92/18639	0.0869565217391304	1.2721998498396	0.292551876691202	0.738151725910672
GO:0008234	cysteine-type peptidase activity	15/1274	187/18639	0.0802139037433155	1.17355333741888	0.297675262183783	0.740839367498758
GO:0046875	ephrin receptor binding	3/1274	28/18639	0.107142857142857	1.56753195783808	0.299026869240882	0.740839367498758
GO:0051019	mitogen-activated protein kinase binding	3/1274	28/18639	0.107142857142857	1.56753195783808	0.299026869240882	0.740839367498758
GO:0141052	histone H3 demethylase activity	3/1274	28/18639	0.107142857142857	1.56753195783808	0.299026869240882	0.740839367498758
GO:0000062	fatty-acyl-CoA binding	2/1274	16/18639	0.125	1.82878728414443	0.299734092721974	0.740839367498758
GO:0015385	sodium:proton antiporter activity	2/1274	16/18639	0.125	1.82878728414443	0.299734092721974	0.740839367498758
GO:0015562	efflux transmembrane transporter activity	2/1274	16/18639	0.125	1.82878728414443	0.299734092721974	0.740839367498758
GO:0017070	U6 snRNA binding	2/1274	16/18639	0.125	1.82878728414443	0.299734092721974	0.740839367498758
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/1274	16/18639	0.125	1.82878728414443	0.299734092721974	0.740839367498758
GO:0000049	tRNA binding	7/1274	80/18639	0.0875	1.2801510989011	0.305678096629588	0.749914041833596
GO:0048306	calcium-dependent protein binding	7/1274	80/18639	0.0875	1.2801510989011	0.305678096629588	0.749914041833596
GO:0001727	lipid kinase activity	4/1274	41/18639	0.0975609756097561	1.42734617299077	0.306845562071361	0.749914041833596
GO:0015175	neutral L-amino acid transmembrane transporter activity	4/1274	41/18639	0.0975609756097561	1.42734617299077	0.306845562071361	0.749914041833596
GO:0140828	metal cation:monoatomic cation antiporter activity	4/1274	41/18639	0.0975609756097561	1.42734617299077	0.306845562071361	0.749914041833596
GO:0015485	cholesterol binding	5/1274	54/18639	0.0925925925925926	1.35465724751439	0.308692902383839	0.751060856246394
GO:0140463	chromatin-protein adaptor activity	5/1274	54/18639	0.0925925925925926	1.35465724751439	0.308692902383839	0.751060856246394
GO:0004629	phospholipase C activity	3/1274	29/18639	0.103448275862069	1.51347913170573	0.3181958127534	0.761135057445609
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	3/1274	29/18639	0.103448275862069	1.51347913170573	0.3181958127534	0.761135057445609
GO:0005416	amino acid:monoatomic cation symporter activity	3/1274	29/18639	0.103448275862069	1.51347913170573	0.3181958127534	0.761135057445609
GO:0035250	UDP-galactosyltransferase activity	3/1274	29/18639	0.103448275862069	1.51347913170573	0.3181958127534	0.761135057445609
GO:0097472	cyclin-dependent protein kinase activity	3/1274	29/18639	0.103448275862069	1.51347913170573	0.3181958127534	0.761135057445609
GO:0032934	sterol binding	6/1274	68/18639	0.0882352941176471	1.29090867116077	0.320105903124463	0.761135057445609
GO:0008509	monoatomic anion transmembrane transporter activity	12/1274	149/18639	0.0805369127516778	1.17827905555614	0.3204991528589	0.761135057445609
GO:0004402	histone acetyltransferase activity	4/1274	42/18639	0.0952380952380952	1.39336174030052	0.322649380106087	0.761135057445609
GO:0048487	beta-tubulin binding	4/1274	42/18639	0.0952380952380952	1.39336174030052	0.322649380106087	0.761135057445609
GO:0004867	serine-type endopeptidase inhibitor activity	8/1274	95/18639	0.0842105263157895	1.2320251177394	0.323317970639074	0.761135057445609
GO:0004550	nucleoside diphosphate kinase activity	2/1274	17/18639	0.117647058823529	1.7212115615477	0.325592293842296	0.761135057445609
GO:0008569	minus-end-directed microtubule motor activity	2/1274	17/18639	0.117647058823529	1.7212115615477	0.325592293842296	0.761135057445609
GO:0015278	intracellularly gated calcium channel activity	2/1274	17/18639	0.117647058823529	1.7212115615477	0.325592293842296	0.761135057445609
GO:0030169	low-density lipoprotein particle binding	2/1274	17/18639	0.117647058823529	1.7212115615477	0.325592293842296	0.761135057445609
GO:0045125	bioactive lipid receptor activity	2/1274	17/18639	0.117647058823529	1.7212115615477	0.325592293842296	0.761135057445609
GO:0048038	quinone binding	2/1274	17/18639	0.117647058823529	1.7212115615477	0.325592293842296	0.761135057445609
GO:0070402	NADPH binding	2/1274	17/18639	0.117647058823529	1.7212115615477	0.325592293842296	0.761135057445609
GO:1901567	fatty acid derivative binding	2/1274	17/18639	0.117647058823529	1.7212115615477	0.325592293842296	0.761135057445609
GO:0016779	nucleotidyltransferase activity	11/1274	136/18639	0.0808823529411765	1.18333294856404	0.326100983327614	0.761135057445609
GO:0004620	phospholipase activity	9/1274	109/18639	0.0825688073394495	1.20800627943485	0.328190251516323	0.764374731095709
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/1274	30/18639	0.1	1.46302982731554	0.337378528209731	0.779115668958914
GO:0016769	transferase activity, transferring nitrogenous groups	3/1274	30/18639	0.1	1.46302982731554	0.337378528209731	0.779115668958914
GO:0032452	histone demethylase activity	3/1274	30/18639	0.1	1.46302982731554	0.337378528209731	0.779115668958914
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/1274	30/18639	0.1	1.46302982731554	0.337378528209731	0.779115668958914
GO:0008135	translation factor activity, RNA binding	7/1274	83/18639	0.0843373493975904	1.23388057725407	0.339268478417176	0.781823766331336
GO:0004860	protein kinase inhibitor activity	7/1274	84/18639	0.0833333333333333	1.21919152276295	0.350576613224893	0.791476900582089
GO:0180051	translation factor activity	7/1274	84/18639	0.0833333333333333	1.21919152276295	0.350576613224893	0.791476900582089
GO:0000900	mRNA regulatory element binding translation repressor activity	2/1274	18/18639	0.111111111111111	1.62558869701727	0.351189961991658	0.791476900582089
GO:0003746	translation elongation factor activity	2/1274	18/18639	0.111111111111111	1.62558869701727	0.351189961991658	0.791476900582089
GO:0008308	voltage-gated monoatomic anion channel activity	2/1274	18/18639	0.111111111111111	1.62558869701727	0.351189961991658	0.791476900582089
GO:0034185	apolipoprotein binding	2/1274	18/18639	0.111111111111111	1.62558869701727	0.351189961991658	0.791476900582089
GO:0035615	clathrin adaptor activity	2/1274	18/18639	0.111111111111111	1.62558869701727	0.351189961991658	0.791476900582089
GO:0070064	proline-rich region binding	2/1274	18/18639	0.111111111111111	1.62558869701727	0.351189961991658	0.791476900582089
GO:0098641	cadherin binding involved in cell-cell adhesion	2/1274	18/18639	0.111111111111111	1.62558869701727	0.351189961991658	0.791476900582089
GO:0001046	core promoter sequence-specific DNA binding	4/1274	44/18639	0.0909090909090909	1.3300271157414	0.354388942763045	0.791476900582089
GO:0043014	alpha-tubulin binding	4/1274	44/18639	0.0909090909090909	1.3300271157414	0.354388942763045	0.791476900582089
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	14/1274	181/18639	0.0773480662983425	1.13162528079655	0.355345253206792	0.791476900582089
GO:0005164	tumor necrosis factor receptor binding	3/1274	31/18639	0.0967741935483871	1.41583531675698	0.356527668060372	0.791476900582089
GO:0005452	solute:inorganic anion antiporter activity	3/1274	31/18639	0.0967741935483871	1.41583531675698	0.356527668060372	0.791476900582089
GO:0016878	acid-thiol ligase activity	3/1274	31/18639	0.0967741935483871	1.41583531675698	0.356527668060372	0.791476900582089
GO:0047499	calcium-independent phospholipase A2 activity	3/1274	31/18639	0.0967741935483871	1.41583531675698	0.356527668060372	0.791476900582089
GO:0070325	lipoprotein particle receptor binding	3/1274	31/18639	0.0967741935483871	1.41583531675698	0.356527668060372	0.791476900582089
GO:0140457	protein demethylase activity	3/1274	31/18639	0.0967741935483871	1.41583531675698	0.356527668060372	0.791476900582089
GO:0043022	ribosome binding	9/1274	112/18639	0.0803571428571429	1.17564896837856	0.357505309595996	0.792034120852917
GO:0008408	3'-5' exonuclease activity	5/1274	58/18639	0.0862068965517241	1.26123260975478	0.363837579173069	0.802799516798877
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	5/1274	58/18639	0.0862068965517241	1.26123260975478	0.363837579173069	0.802799516798877
GO:0008009	chemokine activity	4/1274	45/18639	0.0888888888888889	1.30047095761381	0.370269301372683	0.810912483547517
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	7/1274	86/18639	0.0813953488372093	1.19083823153591	0.373297576538215	0.810912483547517
GO:0050660	flavin adenine dinucleotide binding	7/1274	86/18639	0.0813953488372093	1.19083823153591	0.373297576538215	0.810912483547517
GO:0008378	galactosyltransferase activity	3/1274	32/18639	0.09375	1.37159046310832	0.375599271978055	0.810912483547517
GO:0031369	translation initiation factor binding	3/1274	32/18639	0.09375	1.37159046310832	0.375599271978055	0.810912483547517
GO:0043425	bHLH transcription factor binding	3/1274	32/18639	0.09375	1.37159046310832	0.375599271978055	0.810912483547517
GO:0047498	calcium-dependent phospholipase A2 activity	3/1274	32/18639	0.09375	1.37159046310832	0.375599271978055	0.810912483547517
GO:0071813	lipoprotein particle binding	3/1274	32/18639	0.09375	1.37159046310832	0.375599271978055	0.810912483547517
GO:0071814	protein-lipid complex binding	3/1274	32/18639	0.09375	1.37159046310832	0.375599271978055	0.810912483547517
GO:0120015	sterol transfer activity	3/1274	32/18639	0.09375	1.37159046310832	0.375599271978055	0.810912483547517
GO:0022821	solute:potassium antiporter activity	2/1274	19/18639	0.105263157894737	1.54003139717425	0.37644194190371	0.810912483547517
GO:0120227	acyl-CoA binding	2/1274	19/18639	0.105263157894737	1.54003139717425	0.37644194190371	0.810912483547517
GO:0031267	small GTPase binding	21/1274	283/18639	0.0742049469964664	1.08564050790199	0.380168737330724	0.817325293275127
GO:0008514	organic anion transmembrane transporter activity	20/1274	269/18639	0.0743494423791822	1.08775451845022	0.381177608791563	0.817881089729929
GO:0004521	RNA endonuclease activity	6/1274	73/18639	0.0821917808219178	1.20249026902647	0.382055225148894	0.818153625564429
GO:0008081	phosphoric diester hydrolase activity	7/1274	87/18639	0.0804597701149425	1.17715043577113	0.384690159458769	0.82218092903933
GO:0003684	damaged DNA binding	6/1274	74/18639	0.0810810810810811	1.18624040052611	0.394504922627333	0.83832841500811
GO:0031491	nucleosome binding	6/1274	74/18639	0.0810810810810811	1.18624040052611	0.394504922627333	0.83832841500811
GO:0140311	protein sequestering activity	3/1274	33/18639	0.0909090909090909	1.3300271157414	0.394552731100147	0.83832841500811
GO:0016651	oxidoreductase activity, acting on NAD(P)H	7/1274	88/18639	0.0795454545454545	1.16377372627373	0.396090952979428	0.839959413905791
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/1274	20/18639	0.1	1.46302982731554	0.401275918520165	0.847379106996739
GO:0052745	inositol phosphate phosphatase activity	2/1274	20/18639	0.1	1.46302982731554	0.401275918520165	0.847379106996739
GO:0061733	protein-lysine-acetyltransferase activity	4/1274	47/18639	0.0851063829787234	1.24513176792812	0.401922016804875	0.847379106996739
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	5/1274	61/18639	0.0819672131147541	1.19920477648815	0.405368857753023	0.852996245078754
GO:0046943	carboxylic acid transmembrane transporter activity	14/1274	188/18639	0.074468085106383	1.08949029693711	0.409707231727631	0.860464128291171
GO:0003924	GTPase activity	24/1274	331/18639	0.0725075528700906	1.06080712554601	0.412243477365964	0.861476659270551
GO:0008376	acetylgalactosaminyltransferase activity	3/1274	34/18639	0.0882352941176471	1.29090867116077	0.413350727338072	0.861476659270551
GO:0016831	carboxy-lyase activity	3/1274	34/18639	0.0882352941176471	1.29090867116077	0.413350727338072	0.861476659270551
GO:0030332	cyclin binding	3/1274	34/18639	0.0882352941176471	1.29090867116077	0.413350727338072	0.861476659270551
GO:0005342	organic acid transmembrane transporter activity	14/1274	189/18639	0.0740740740740741	1.08372579801151	0.417527293789607	0.86555570406517
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/1274	48/18639	0.0833333333333333	1.21919152276295	0.417646594634858	0.86555570406517
GO:0019210	kinase inhibitor activity	7/1274	90/18639	0.0777777777777778	1.13791208791209	0.418878860174207	0.86555570406517
GO:0003735	structural constituent of ribosome	13/1274	175/18639	0.0742857142857143	1.0868221574344	0.419361938847051	0.86555570406517
GO:0005248	voltage-gated sodium channel activity	2/1274	21/18639	0.0952380952380952	1.39336174030052	0.425631061815533	0.86555570406517
GO:0009975	cyclase activity	2/1274	21/18639	0.0952380952380952	1.39336174030052	0.425631061815533	0.86555570406517
GO:0010314	phosphatidylinositol-5-phosphate binding	2/1274	21/18639	0.0952380952380952	1.39336174030052	0.425631061815533	0.86555570406517
GO:0015125	bile acid transmembrane transporter activity	2/1274	21/18639	0.0952380952380952	1.39336174030052	0.425631061815533	0.86555570406517
GO:0015174	basic amino acid transmembrane transporter activity	2/1274	21/18639	0.0952380952380952	1.39336174030052	0.425631061815533	0.86555570406517
GO:0035613	RNA stem-loop binding	2/1274	21/18639	0.0952380952380952	1.39336174030052	0.425631061815533	0.86555570406517
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/1274	21/18639	0.0952380952380952	1.39336174030052	0.425631061815533	0.86555570406517
GO:0051010	microtubule plus-end binding	2/1274	21/18639	0.0952380952380952	1.39336174030052	0.425631061815533	0.86555570406517
GO:0140312	cargo adaptor activity	2/1274	21/18639	0.0952380952380952	1.39336174030052	0.425631061815533	0.86555570406517
GO:0045296	cadherin binding	24/1274	334/18639	0.0718562874251497	1.05127891783153	0.429975190137234	0.872761559123995
GO:0004623	phospholipase A2 activity	3/1274	35/18639	0.0857142857142857	1.25402556627046	0.431959152275587	0.873535205900537
GO:0034061	DNA polymerase activity	3/1274	35/18639	0.0857142857142857	1.25402556627046	0.431959152275587	0.873535205900537
GO:0048020	CCR chemokine receptor binding	4/1274	50/18639	0.08	1.17042386185243	0.448782709390676	0.879865047082592
GO:0008649	rRNA methyltransferase activity	2/1274	22/18639	0.0909090909090909	1.3300271157414	0.449456796662538	0.879865047082592
GO:0008970	phospholipase A1 activity	2/1274	22/18639	0.0909090909090909	1.3300271157414	0.449456796662538	0.879865047082592
GO:0033691	sialic acid binding	2/1274	22/18639	0.0909090909090909	1.3300271157414	0.449456796662538	0.879865047082592
GO:0070034	telomerase RNA binding	2/1274	22/18639	0.0909090909090909	1.3300271157414	0.449456796662538	0.879865047082592
GO:0019842	vitamin binding	11/1274	150/18639	0.0733333333333333	1.0728885400314	0.449722312863595	0.879865047082592
GO:0004033	aldo-keto reductase (NADPH) activity	3/1274	36/18639	0.0833333333333333	1.21919152276295	0.450347009612341	0.879865047082592
GO:0045505	dynein intermediate chain binding	3/1274	36/18639	0.0833333333333333	1.21919152276295	0.450347009612341	0.879865047082592
GO:0055106	ubiquitin-protein transferase regulator activity	3/1274	36/18639	0.0833333333333333	1.21919152276295	0.450347009612341	0.879865047082592
GO:0002020	protease binding	10/1274	136/18639	0.0735294117647059	1.07575722596731	0.452957131743201	0.879865047082592
GO:0038024	cargo receptor activity	5/1274	65/18639	0.0769230769230769	1.12540755947349	0.460113604595416	0.879865047082592
GO:0005496	steroid binding	8/1274	108/18639	0.0740740740740741	1.08372579801151	0.460114339940843	0.879865047082592
GO:0003743	translation initiation factor activity	4/1274	51/18639	0.0784313725490196	1.14747437436513	0.464154469784625	0.879865047082592
GO:0005272	sodium channel activity	4/1274	51/18639	0.0784313725490196	1.14747437436513	0.464154469784625	0.879865047082592
GO:0004602	glutathione peroxidase activity	2/1274	23/18639	0.0869565217391304	1.2721998498396	0.472711686996433	0.879865047082592
GO:0016849	phosphorus-oxygen lyase activity	2/1274	23/18639	0.0869565217391304	1.2721998498396	0.472711686996433	0.879865047082592
GO:0043274	phospholipase binding	2/1274	23/18639	0.0869565217391304	1.2721998498396	0.472711686996433	0.879865047082592
GO:0140102	catalytic activity, acting on a rRNA	2/1274	23/18639	0.0869565217391304	1.2721998498396	0.472711686996433	0.879865047082592
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/1274	52/18639	0.0769230769230769	1.12540755947349	0.479371069508037	0.879865047082592
GO:0004222	metalloendopeptidase activity	8/1274	110/18639	0.0727272727272727	1.06402169259312	0.480967406305305	0.879865047082592
GO:0042887	amide transmembrane transporter activity	3/1274	38/18639	0.0789473684210526	1.15502354788069	0.486351923501905	0.879865047082592
GO:0008237	metallopeptidase activity	13/1274	184/18639	0.0706521739130435	1.03366237799468	0.492280572096608	0.879865047082592
GO:0034212	protein N-acetyltransferase activity	4/1274	53/18639	0.0754716981132075	1.10417345457777	0.494415932535342	0.879865047082592
GO:1901505	carbohydrate derivative transmembrane transporter activity	4/1274	53/18639	0.0754716981132075	1.10417345457777	0.494415932535342	0.879865047082592
GO:0004622	lysophospholipase activity	2/1274	24/18639	0.0833333333333333	1.21919152276295	0.49536242441897	0.879865047082592
GO:0005315	phosphate transmembrane transporter activity	2/1274	24/18639	0.0833333333333333	1.21919152276295	0.49536242441897	0.879865047082592
GO:0015149	hexose transmembrane transporter activity	2/1274	24/18639	0.0833333333333333	1.21919152276295	0.49536242441897	0.879865047082592
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/1274	24/18639	0.0833333333333333	1.21919152276295	0.49536242441897	0.879865047082592
GO:0050699	WW domain binding	2/1274	24/18639	0.0833333333333333	1.21919152276295	0.49536242441897	0.879865047082592
GO:0055056	D-glucose transmembrane transporter activity	2/1274	24/18639	0.0833333333333333	1.21919152276295	0.49536242441897	0.879865047082592
GO:0060229	lipase activator activity	2/1274	24/18639	0.0833333333333333	1.21919152276295	0.49536242441897	0.879865047082592
GO:0001540	amyloid-beta binding	6/1274	83/18639	0.072289156626506	1.05761192336063	0.504752507985002	0.879865047082592
GO:0030165	PDZ domain binding	6/1274	83/18639	0.072289156626506	1.05761192336063	0.504752507985002	0.879865047082592
GO:0001094	TFIID-class transcription factor complex binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0004955	prostaglandin receptor activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0008190	eukaryotic initiation factor 4E binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0015279	store-operated calcium channel activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0016783	sulfurtransferase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0019531	oxalate transmembrane transporter activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0031434	mitogen-activated protein kinase kinase binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0032052	bile acid binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0032356	oxidized DNA binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0035256	G protein-coupled glutamate receptor binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0035374	chondroitin sulfate binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0042975	peroxisome proliferator activated receptor binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0043121	neurotrophin binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0043295	glutathione binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0047429	nucleoside triphosphate diphosphatase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0070739	protein-glutamic acid ligase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0070740	tubulin-glutamic acid ligase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0071723	lipopeptide binding	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0140999	histone H3K4 trimethyltransferase activity	1/1274	10/18639	0.1	1.46302982731554	0.507456218002538	0.879865047082592
GO:0042626	ATPase-coupled transmembrane transporter activity	7/1274	98/18639	0.0714285714285714	1.04502130522539	0.508553722994469	0.879865047082592
GO:0005126	cytokine receptor binding	19/1274	275/18639	0.0690909090909091	1.01082060796347	0.515007557113149	0.879865047082592
GO:0031406	carboxylic acid binding	13/1274	187/18639	0.0695187165775401	1.01707955909637	0.51621841794199	0.879865047082592
GO:0051117	ATPase binding	6/1274	84/18639	0.0714285714285714	1.04502130522539	0.516612192197318	0.879865047082592
GO:0004709	MAP kinase kinase kinase activity	2/1274	25/18639	0.08	1.17042386185243	0.517382912194974	0.879865047082592
GO:0015645	fatty acid ligase activity	2/1274	25/18639	0.08	1.17042386185243	0.517382912194974	0.879865047082592
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/1274	25/18639	0.08	1.17042386185243	0.517382912194974	0.879865047082592
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/1274	25/18639	0.08	1.17042386185243	0.517382912194974	0.879865047082592
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/1274	25/18639	0.08	1.17042386185243	0.517382912194974	0.879865047082592
GO:0019707	protein-cysteine S-acyltransferase activity	2/1274	25/18639	0.08	1.17042386185243	0.517382912194974	0.879865047082592
GO:0047617	fatty acyl-CoA hydrolase activity	2/1274	25/18639	0.08	1.17042386185243	0.517382912194974	0.879865047082592
GO:0120515	fatty acid-CoA ligase activity	2/1274	25/18639	0.08	1.17042386185243	0.517382912194974	0.879865047082592
GO:0015144	carbohydrate transmembrane transporter activity	3/1274	40/18639	0.075	1.09727237048666	0.521175310047296	0.879865047082592
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3/1274	40/18639	0.075	1.09727237048666	0.521175310047296	0.879865047082592
GO:0032451	demethylase activity	3/1274	40/18639	0.075	1.09727237048666	0.521175310047296	0.879865047082592
GO:0071949	FAD binding	3/1274	40/18639	0.075	1.09727237048666	0.521175310047296	0.879865047082592
GO:0098632	cell-cell adhesion mediator activity	4/1274	55/18639	0.0727272727272727	1.06402169259312	0.523930578329651	0.879865047082592
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/1274	70/18639	0.0714285714285714	1.04502130522539	0.526267045917373	0.879865047082592
GO:0043177	organic acid binding	13/1274	189/18639	0.0687830687830688	1.00631681243926	0.532004791058073	0.879865047082592
GO:0016298	lipase activity	9/1274	130/18639	0.0692307692307692	1.01286680352614	0.533783006135593	0.879865047082592
GO:0016798	hydrolase activity, acting on glycosyl bonds	9/1274	130/18639	0.0692307692307692	1.01286680352614	0.533783006135593	0.879865047082592
GO:0008194	UDP-glycosyltransferase activity	10/1274	145/18639	0.0689655172413793	1.00898608780382	0.535395665709071	0.879865047082592
GO:0004812	aminoacyl-tRNA ligase activity	3/1274	41/18639	0.0731707317073171	1.07050962974308	0.538096079624344	0.879865047082592
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/1274	41/18639	0.0731707317073171	1.07050962974308	0.538096079624344	0.879865047082592
GO:0016875	ligase activity, forming carbon-oxygen bonds	3/1274	41/18639	0.0731707317073171	1.07050962974308	0.538096079624344	0.879865047082592
GO:0016877	ligase activity, forming carbon-sulfur bonds	3/1274	41/18639	0.0731707317073171	1.07050962974308	0.538096079624344	0.879865047082592
GO:0004529	DNA exonuclease activity	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0008143	poly(A) binding	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0008157	protein phosphatase 1 binding	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0008198	ferrous iron binding	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0015145	monosaccharide transmembrane transporter activity	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0015216	purine nucleotide transmembrane transporter activity	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0016289	acyl-CoA hydrolase activity	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0051139	metal cation:proton antiporter activity	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0120014	phospholipid transfer activity	2/1274	26/18639	0.0769230769230769	1.12540755947349	0.538753436341867	0.879865047082592
GO:0003953	NAD+ nucleosidase activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0004016	adenylate cyclase activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0004954	prostanoid receptor activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0005114	type II transforming growth factor beta receptor binding	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0005536	D-glucose binding	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0008172	S-methyltransferase activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0008271	secondary active sulfate transmembrane transporter activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0015217	ADP transmembrane transporter activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0019107	myristoyltransferase activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0019215	intermediate filament binding	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0031731	CCR6 chemokine receptor binding	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0032794	GTPase activating protein binding	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0035252	UDP-xylosyltransferase activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0042285	xylosyltransferase activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0047676	arachidonate-CoA ligase activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0048185	activin binding	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0048407	platelet-derived growth factor binding	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0070990	snRNP binding	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0140537	transcription regulator activator activity	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:1900750	oligopeptide binding	1/1274	11/18639	0.0909090909090909	1.3300271157414	0.54114030079092	0.879865047082592
GO:0061630	ubiquitin protein ligase activity	24/1274	353/18639	0.0679886685552408	0.994694500157875	0.54160200065439	0.879865047082592
GO:0005178	integrin binding	11/1274	161/18639	0.0683229813664596	0.999585596302544	0.545422781112788	0.879865047082592
GO:0015171	amino acid transmembrane transporter activity	7/1274	102/18639	0.0686274509803922	1.00404007756949	0.551636045399305	0.879865047082592
GO:0042379	chemokine receptor binding	5/1274	72/18639	0.0694444444444444	1.01599293563579	0.551723863707558	0.879865047082592
GO:1990782	protein tyrosine kinase binding	8/1274	117/18639	0.0683760683760684	1.00036227508755	0.552009200632595	0.879865047082592
GO:0004601	peroxidase activity	4/1274	57/18639	0.0701754385964912	1.02668759811617	0.55259113235907	0.879865047082592
GO:0016504	peptidase activator activity	4/1274	57/18639	0.0701754385964912	1.02668759811617	0.55259113235907	0.879865047082592
GO:0031492	nucleosomal DNA binding	3/1274	42/18639	0.0714285714285714	1.04502130522539	0.55466890266421	0.879865047082592
GO:0035198	miRNA binding	3/1274	42/18639	0.0714285714285714	1.04502130522539	0.55466890266421	0.879865047082592
GO:0051879	Hsp90 protein binding	3/1274	42/18639	0.0714285714285714	1.04502130522539	0.55466890266421	0.879865047082592
GO:0015631	tubulin binding	26/1274	385/18639	0.0675324675324675	0.988020143122184	0.555155549140873	0.879865047082592
GO:0004364	glutathione transferase activity	2/1274	27/18639	0.0740740740740741	1.08372579801151	0.559459916200059	0.879865047082592
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/1274	27/18639	0.0740740740740741	1.08372579801151	0.559459916200059	0.879865047082592
GO:0015252	proton channel activity	2/1274	27/18639	0.0740740740740741	1.08372579801151	0.559459916200059	0.879865047082592
GO:0008200	ion channel inhibitor activity	3/1274	43/18639	0.0697674418604651	1.02071848417363	0.570881074981689	0.879865047082592
GO:0008375	acetylglucosaminyltransferase activity	3/1274	43/18639	0.0697674418604651	1.02071848417363	0.570881074981689	0.879865047082592
GO:0051015	actin filament binding	14/1274	209/18639	0.0669856459330144	0.98001998001998	0.570953414796061	0.879865047082592
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0004300	enoyl-CoA hydratase activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0004859	phospholipase inhibitor activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0005025	transforming growth factor beta receptor activity, type I	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0005026	transforming growth factor beta receptor activity, type II	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0005049	nuclear export signal receptor activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0005078	MAP-kinase scaffold activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0005165	neurotrophin receptor binding	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0015132	prostaglandin transmembrane transporter activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0015166	polyol transmembrane transporter activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0015368	calcium:monoatomic cation antiporter activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0016208	AMP binding	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0016361	activin receptor activity, type I	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0016362	activin receptor activity, type II	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0017002	activin receptor activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0017166	vinculin binding	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0035251	UDP-glucosyltransferase activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0035497	cAMP response element binding	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0042301	phosphate ion binding	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0070008	serine-type exopeptidase activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0140900	chloride:bicarbonate antiporter activity	1/1274	12/18639	0.0833333333333333	1.21919152276295	0.572522481207087	0.879865047082592
GO:0048029	monosaccharide binding	5/1274	74/18639	0.0675675675675676	0.988533667105096	0.576496207320938	0.879865047082592
GO:0015103	inorganic anion transmembrane transporter activity	11/1274	165/18639	0.0666666666666667	0.975353218210361	0.578773639134176	0.879865047082592
GO:0004842	ubiquitin-protein transferase activity	30/1274	449/18639	0.066815144766147	0.97752549709279	0.57938489521436	0.879865047082592
GO:0051119	sugar transmembrane transporter activity	2/1274	28/18639	0.0714285714285714	1.04502130522539	0.579493227504611	0.879865047082592
GO:0004879	nuclear receptor activity	4/1274	59/18639	0.0677966101694915	0.991884628688503	0.580309492610126	0.879865047082592
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	4/1274	59/18639	0.0677966101694915	0.991884628688503	0.580309492610126	0.879865047082592
GO:0036002	pre-mRNA binding	4/1274	59/18639	0.0677966101694915	0.991884628688503	0.580309492610126	0.879865047082592
GO:0003954	NADH dehydrogenase activity	3/1274	44/18639	0.0681818181818182	0.997520336806051	0.586721962705004	0.879865047082592
GO:0016248	channel inhibitor activity	3/1274	44/18639	0.0681818181818182	0.997520336806051	0.586721962705004	0.879865047082592
GO:0016790	thiolester hydrolase activity	3/1274	44/18639	0.0681818181818182	0.997520336806051	0.586721962705004	0.879865047082592
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/1274	44/18639	0.0681818181818182	0.997520336806051	0.586721962705004	0.879865047082592
GO:0004540	RNA nuclease activity	8/1274	121/18639	0.0661157024793388	0.967292447811928	0.590742910589556	0.879865047082592
GO:0008013	beta-catenin binding	7/1274	106/18639	0.0660377358490566	0.966151772755546	0.593004273397464	0.879865047082592
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/1274	60/18639	0.0666666666666667	0.975353218210361	0.59379275813768	0.879865047082592
GO:0098531	ligand-modulated transcription factor activity	4/1274	60/18639	0.0666666666666667	0.975353218210361	0.59379275813768	0.879865047082592
GO:0005525	GTP binding	25/1274	378/18639	0.0661375661375661	0.967612319653136	0.598165195203077	0.879865047082592
GO:0003785	actin monomer binding	2/1274	29/18639	0.0689655172413793	1.00898608780382	0.598848591560256	0.879865047082592
GO:0016417	S-acyltransferase activity	2/1274	29/18639	0.0689655172413793	1.00898608780382	0.598848591560256	0.879865047082592
GO:0051861	glycolipid binding	2/1274	29/18639	0.0689655172413793	1.00898608780382	0.598848591560256	0.879865047082592
GO:0099604	ligand-gated calcium channel activity	2/1274	29/18639	0.0689655172413793	1.00898608780382	0.598848591560256	0.879865047082592
GO:0051536	iron-sulfur cluster binding	5/1274	76/18639	0.0657894736842105	0.962519623233909	0.600525618513303	0.879865047082592
GO:0098631	cell adhesion mediator activity	5/1274	76/18639	0.0657894736842105	0.962519623233909	0.600525618513303	0.879865047082592
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0004535	poly(A)-specific ribonuclease activity	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0009982	pseudouridine synthase activity	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0019104	DNA N-glycosylase activity	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0031432	titin binding	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0032396	inhibitory MHC class I receptor activity	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0045159	myosin II binding	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0070123	transforming growth factor beta receptor activity, type III	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0071714	icosanoid transmembrane transporter activity	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0089720	caspase binding	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0097157	pre-mRNA intronic binding	1/1274	13/18639	0.0769230769230769	1.12540755947349	0.601759951489053	0.879865047082592
GO:0046915	transition metal ion transmembrane transporter activity	3/1274	45/18639	0.0666666666666667	0.975353218210361	0.602182867085884	0.879865047082592
GO:0051539	4 iron, 4 sulfur cluster binding	3/1274	45/18639	0.0666666666666667	0.975353218210361	0.602182867085884	0.879865047082592
GO:0141110	transporter inhibitor activity	3/1274	45/18639	0.0666666666666667	0.975353218210361	0.602182867085884	0.879865047082592
GO:0003774	cytoskeletal motor activity	10/1274	153/18639	0.065359477124183	0.956228645304276	0.604730503133156	0.88124563414545
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	15/1274	229/18639	0.0655021834061135	0.958316480774372	0.60615772522411	0.88124563414545
GO:0019905	syntaxin binding	4/1274	61/18639	0.0655737704918033	0.959363821190519	0.607015487989235	0.88124563414545
GO:0051540	metal cluster binding	5/1274	77/18639	0.0649350649350649	0.950019368386715	0.612246319463181	0.88124563414545
GO:0005506	iron ion binding	10/1274	154/18639	0.0649350649350649	0.950019368386715	0.613043831190139	0.88124563414545
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3/1274	46/18639	0.0652173913043478	0.954149887379701	0.617256892085883	0.88124563414545
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/1274	30/18639	0.0666666666666667	0.975353218210361	0.617525024656722	0.88124563414545
GO:0015215	nucleotide transmembrane transporter activity	2/1274	30/18639	0.0666666666666667	0.975353218210361	0.617525024656722	0.88124563414545
GO:0031210	phosphatidylcholine binding	2/1274	30/18639	0.0666666666666667	0.975353218210361	0.617525024656722	0.88124563414545
GO:0051721	protein phosphatase 2A binding	2/1274	30/18639	0.0666666666666667	0.975353218210361	0.617525024656722	0.88124563414545
GO:0070566	adenylyltransferase activity	2/1274	30/18639	0.0666666666666667	0.975353218210361	0.617525024656722	0.88124563414545
GO:0015179	L-amino acid transmembrane transporter activity	4/1274	62/18639	0.0645161290322581	0.943890211171317	0.619971486653315	0.88124563414545
GO:0016410	N-acyltransferase activity	6/1274	94/18639	0.0638297872340425	0.93384882594609	0.62798145803766	0.88124563414545
GO:0004065	arylsulfatase activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0005161	platelet-derived growth factor receptor binding	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0005344	oxygen carrier activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0005347	ATP transmembrane transporter activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0008494	translation activator activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0015926	glucosidase activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0016530	metallochaperone activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0031404	chloride ion binding	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0032036	myosin heavy chain binding	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0042043	neurexin family protein binding	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0043176	amine binding	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0044548	S100 protein binding	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0046030	inositol trisphosphate phosphatase activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0098599	palmitoyl hydrolase activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:0098821	BMP receptor activity	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:1901612	cardiolipin binding	1/1274	14/18639	0.0714285714285714	1.04502130522539	0.628999177399229	0.88124563414545
GO:1901682	sulfur compound transmembrane transporter activity	4/1274	63/18639	0.0634920634920635	0.92890782686701	0.632655502764463	0.88523042106966
GO:0016411	acylglycerol O-acyltransferase activity	2/1274	31/18639	0.0645161290322581	0.943890211171317	0.635524842353022	0.886968089839685
GO:0017147	Wnt-protein binding	2/1274	31/18639	0.0645161290322581	0.943890211171317	0.635524842353022	0.886968089839685
GO:0061659	ubiquitin-like protein ligase activity	24/1274	372/18639	0.0645161290322581	0.943890211171317	0.646292374455339	0.888257193409873
GO:0016407	acetyltransferase activity	6/1274	96/18639	0.0625	0.914393642072214	0.648390294310925	0.888257193409873
GO:0019787	ubiquitin-like protein transferase activity	31/1274	479/18639	0.0647181628392484	0.946846026028847	0.651659414055132	0.888257193409873
GO:0022884	macromolecule transmembrane transporter activity	2/1274	32/18639	0.0625	0.914393642072214	0.652853213711353	0.888257193409873
GO:0042910	xenobiotic transmembrane transporter activity	2/1274	32/18639	0.0625	0.914393642072214	0.652853213711353	0.888257193409873
GO:0070717	poly-purine tract binding	2/1274	32/18639	0.0625	0.914393642072214	0.652853213711353	0.888257193409873
GO:0140142	nucleocytoplasmic carrier activity	2/1274	32/18639	0.0625	0.914393642072214	0.652853213711353	0.888257193409873
GO:0031490	chromatin DNA binding	8/1274	128/18639	0.0625	0.914393642072214	0.654316377637083	0.888257193409873
GO:0004467	long-chain fatty acid-CoA ligase activity	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0004559	alpha-mannosidase activity	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0004953	icosanoid receptor activity	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0008242	omega peptidase activity	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0015116	sulfate transmembrane transporter activity	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0016846	carbon-sulfur lyase activity	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0031005	filamin binding	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0047372	monoacylglycerol lipase activity	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0050700	CARD domain binding	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0050780	dopamine receptor binding	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0051371	muscle alpha-actinin binding	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0061578	K63-linked deubiquitinase activity	1/1274	15/18639	0.0666666666666667	0.975353218210361	0.654376629640484	0.888257193409873
GO:0004175	endopeptidase activity	26/1274	405/18639	0.0641975308641975	0.939229024943311	0.659767374691946	0.894460744296295
GO:0008235	metalloexopeptidase activity	4/1274	66/18639	0.0606060606060606	0.886684743827601	0.669036328472804	0.900172006485026
GO:0019239	deaminase activity	2/1274	33/18639	0.0606060606060606	0.886684743827601	0.669517760976592	0.900172006485026
GO:0003688	DNA replication origin binding	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0005024	transforming growth factor beta receptor activity	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0005149	interleukin-1 receptor binding	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0005521	lamin binding	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0008142	oxysterol binding	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0008296	3'-5'-DNA exonuclease activity	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0015378	sodium:chloride symporter activity	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0015923	mannosidase activity	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0034450	ubiquitin-ubiquitin ligase activity	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0055102	lipase inhibitor activity	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0070411	I-SMAD binding	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/1274	16/18639	0.0625	0.914393642072214	0.678019465435052	0.900172006485026
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/1274	34/18639	0.0588235294117647	0.860605780773848	0.685528200579	0.906827352707657
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/1274	34/18639	0.0588235294117647	0.860605780773848	0.685528200579	0.906827352707657
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/1274	34/18639	0.0588235294117647	0.860605780773848	0.685528200579	0.906827352707657
GO:0009055	electron transfer activity	7/1274	116/18639	0.0603448275862069	0.882862826828344	0.687103037691094	0.906949373212229
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/1274	17/18639	0.0588235294117647	0.860605780773848	0.700046163659599	0.906949373212229
GO:0005092	GDP-dissociation inhibitor activity	1/1274	17/18639	0.0588235294117647	0.860605780773848	0.700046163659599	0.906949373212229
GO:0008429	phosphatidylethanolamine binding	1/1274	17/18639	0.0588235294117647	0.860605780773848	0.700046163659599	0.906949373212229
GO:0008484	sulfuric ester hydrolase activity	1/1274	17/18639	0.0588235294117647	0.860605780773848	0.700046163659599	0.906949373212229
GO:0017110	nucleoside diphosphate phosphatase activity	1/1274	17/18639	0.0588235294117647	0.860605780773848	0.700046163659599	0.906949373212229
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/1274	17/18639	0.0588235294117647	0.860605780773848	0.700046163659599	0.906949373212229
GO:0051787	misfolded protein binding	1/1274	17/18639	0.0588235294117647	0.860605780773848	0.700046163659599	0.906949373212229
GO:0000175	3'-5'-RNA exonuclease activity	2/1274	35/18639	0.0571428571428571	0.836017044180309	0.700896021688298	0.906949373212229
GO:0043015	gamma-tubulin binding	2/1274	35/18639	0.0571428571428571	0.836017044180309	0.700896021688298	0.906949373212229
GO:0008080	N-acetyltransferase activity	4/1274	69/18639	0.0579710144927536	0.848133233226401	0.702861150549592	0.906949373212229
GO:0008238	exopeptidase activity	6/1274	102/18639	0.0588235294117647	0.860605780773848	0.705372074348136	0.906949373212229
GO:0015399	primary active transmembrane transporter activity	10/1274	166/18639	0.0602409638554217	0.881343269467194	0.705382222240642	0.906949373212229
GO:0019001	guanyl nucleotide binding	25/1274	400/18639	0.0625	0.914393642072214	0.708831249165042	0.906949373212229
GO:0032561	guanyl ribonucleotide binding	25/1274	400/18639	0.0625	0.914393642072214	0.708831249165042	0.906949373212229
GO:0004864	protein phosphatase inhibitor activity	3/1274	53/18639	0.0566037735849057	0.828130090933325	0.711684114338385	0.906949373212229
GO:0005246	calcium channel regulator activity	3/1274	53/18639	0.0566037735849057	0.828130090933325	0.711684114338385	0.906949373212229
GO:0005544	calcium-dependent phospholipid binding	3/1274	53/18639	0.0566037735849057	0.828130090933325	0.711684114338385	0.906949373212229
GO:0016251	RNA polymerase II general transcription initiation factor activity	3/1274	53/18639	0.0566037735849057	0.828130090933325	0.711684114338385	0.906949373212229
GO:0016860	intramolecular oxidoreductase activity	3/1274	53/18639	0.0566037735849057	0.828130090933325	0.711684114338385	0.906949373212229
GO:0140296	general transcription initiation factor binding	3/1274	53/18639	0.0566037735849057	0.828130090933325	0.711684114338385	0.906949373212229
GO:0005253	monoatomic anion channel activity	6/1274	103/18639	0.058252427184466	0.852250384844005	0.714231037894159	0.906949373212229
GO:0016409	palmitoyltransferase activity	2/1274	36/18639	0.0555555555555556	0.812794348508634	0.715634198869236	0.906949373212229
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/1274	36/18639	0.0555555555555556	0.812794348508634	0.715634198869236	0.906949373212229
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/1274	36/18639	0.0555555555555556	0.812794348508634	0.715634198869236	0.906949373212229
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/1274	36/18639	0.0555555555555556	0.812794348508634	0.715634198869236	0.906949373212229
GO:0044325	transmembrane transporter binding	8/1274	136/18639	0.0588235294117647	0.860605780773848	0.719400647797787	0.906949373212229
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0004706	JUN kinase kinase kinase activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0004970	glutamate-gated receptor activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0008409	5'-3' exonuclease activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0015172	acidic amino acid transmembrane transporter activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0015373	monoatomic anion:sodium symporter activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0016854	racemase and epimerase activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0017075	syntaxin-1 binding	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0022851	GABA-gated chloride ion channel activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0030228	lipoprotein particle receptor activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0032393	MHC class I receptor activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0050811	GABA receptor binding	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0070628	proteasome binding	1/1274	18/18639	0.0555555555555556	0.812794348508634	0.72056711669889	0.906949373212229
GO:0140299	molecular sensor activity	4/1274	71/18639	0.0563380281690141	0.824242156234108	0.72398095098439	0.910195197892716
GO:0016755	aminoacyltransferase activity	31/1274	496/18639	0.0625	0.914393642072214	0.725103303017575	0.91055599111654
GO:0015078	proton transmembrane transporter activity	11/1274	185/18639	0.0594594594594595	0.869909627052484	0.726531663269744	0.911024687392276
GO:0015108	chloride transmembrane transporter activity	7/1274	121/18639	0.0578512396694215	0.846380891835437	0.728526662291244	0.911024687392276
GO:0023023	MHC protein complex binding	2/1274	37/18639	0.0540540540540541	0.790826933684077	0.729756935684377	0.911024687392276
GO:0140313	molecular sequestering activity	3/1274	55/18639	0.0545454545454545	0.798016269444841	0.735109452577012	0.911024687392276
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0004890	GABA-A receptor activity	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0008301	DNA binding, bending	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0008381	mechanosensitive monoatomic ion channel activity	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0015245	fatty acid transmembrane transporter activity	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0030506	ankyrin binding	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0031420	alkali metal ion binding	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0034987	immunoglobulin receptor binding	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0046527	glucosyltransferase activity	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0070003	threonine-type peptidase activity	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0097001	ceramide binding	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:1990380	K48-linked deubiquitinase activity	1/1274	19/18639	0.0526315789473684	0.770015698587127	0.739685181965289	0.911024687392276
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/1274	38/18639	0.0526315789473684	0.770015698587127	0.743279436361181	0.914418268209579
GO:0019212	phosphatase inhibitor activity	3/1274	56/18639	0.0535714285714286	0.78376597891904	0.746245446564062	0.914771663429499
GO:0030170	pyridoxal phosphate binding	3/1274	56/18639	0.0535714285714286	0.78376597891904	0.746245446564062	0.914771663429499
GO:0170055	lipid transmembrane transporter activity	3/1274	56/18639	0.0535714285714286	0.78376597891904	0.746245446564062	0.914771663429499
GO:0140375	immune receptor activity	9/1274	156/18639	0.0576923076923077	0.84405566960512	0.746923651791058	0.914771663429499
GO:0035064	methylated histone binding	4/1274	74/18639	0.0540540540540541	0.790826933684077	0.753533398550444	0.917412059395106
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	5/1274	91/18639	0.0549450549450549	0.803862542481067	0.753704650070747	0.917412059395106
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/1274	39/18639	0.0512820512820513	0.750271706315662	0.756217702889538	0.917412059395106
GO:0070279	vitamin B6 binding	3/1274	57/18639	0.0526315789473684	0.770015698587127	0.757004019575451	0.917412059395106
GO:0000339	RNA cap binding	1/1274	20/18639	0.05	0.731514913657771	0.757496195830822	0.917412059395106
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/1274	20/18639	0.05	0.731514913657771	0.757496195830822	0.917412059395106
GO:0016004	phospholipase activator activity	1/1274	20/18639	0.05	0.731514913657771	0.757496195830822	0.917412059395106
GO:0016408	C-acyltransferase activity	1/1274	20/18639	0.05	0.731514913657771	0.757496195830822	0.917412059395106
GO:0030742	GTP-dependent protein binding	1/1274	20/18639	0.05	0.731514913657771	0.757496195830822	0.917412059395106
GO:0061608	nuclear import signal receptor activity	1/1274	20/18639	0.05	0.731514913657771	0.757496195830822	0.917412059395106
GO:0061980	regulatory RNA binding	3/1274	58/18639	0.0517241379310345	0.756739565852866	0.767391172804684	0.924681354423166
GO:0004177	aminopeptidase activity	2/1274	40/18639	0.05	0.731514913657771	0.768588355144393	0.924681354423166
GO:0004532	RNA exonuclease activity	2/1274	40/18639	0.05	0.731514913657771	0.768588355144393	0.924681354423166
GO:0050997	quaternary ammonium group binding	2/1274	40/18639	0.05	0.731514913657771	0.768588355144393	0.924681354423166
GO:0061791	GTPase motor activity	2/1274	40/18639	0.05	0.731514913657771	0.768588355144393	0.924681354423166
GO:1990606	membrane scission GTPase motor activity	2/1274	40/18639	0.05	0.731514913657771	0.768588355144393	0.924681354423166
GO:0140034	methylation-dependent protein binding	4/1274	76/18639	0.0526315789473684	0.770015698587127	0.771841659247624	0.927571564035182
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/1274	21/18639	0.0476190476190476	0.696680870150258	0.774089452531586	0.9292483516073
GO:0015459	potassium channel regulator activity	3/1274	59/18639	0.0508474576271186	0.743913471516377	0.777413405672249	0.931023053689204
GO:0070888	E-box binding	3/1274	59/18639	0.0508474576271186	0.743913471516377	0.777413405672249	0.931023053689204
GO:0061134	peptidase regulator activity	13/1274	226/18639	0.0575221238938053	0.841565829871772	0.778563521455124	0.931023053689204
GO:0004866	endopeptidase inhibitor activity	9/1274	161/18639	0.0559006211180124	0.817842760611172	0.778984426572985	0.931023053689204
GO:0033038	bitter taste receptor activity	1/1274	22/18639	0.0454545454545455	0.665013557870701	0.789548150430112	0.939527820926662
GO:0034062	5'-3' RNA polymerase activity	1/1274	22/18639	0.0454545454545455	0.665013557870701	0.789548150430112	0.939527820926662
GO:0061133	endopeptidase activator activity	1/1274	22/18639	0.0454545454545455	0.665013557870701	0.789548150430112	0.939527820926662
GO:0097747	RNA polymerase activity	1/1274	22/18639	0.0454545454545455	0.665013557870701	0.789548150430112	0.939527820926662
GO:0016859	cis-trans isomerase activity	2/1274	42/18639	0.0476190476190476	0.696680870150258	0.791695450296405	0.941055660657668
GO:0033293	monocarboxylic acid binding	4/1274	79/18639	0.0506329113924051	0.740774596109135	0.797276259561624	0.944294494144632
GO:0033218	amide binding	14/1274	247/18639	0.0566801619433198	0.829247675401522	0.802322885882509	0.944294494144632
GO:0005245	voltage-gated calcium channel activity	2/1274	43/18639	0.0465116279069767	0.680478989449089	0.802466883238586	0.944294494144632
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/1274	43/18639	0.0465116279069767	0.680478989449089	0.802466883238586	0.944294494144632
GO:0000295	adenine nucleotide transmembrane transporter activity	1/1274	23/18639	0.0434782608695652	0.636099924919801	0.803949807858916	0.944294494144632
GO:0016917	GABA receptor activity	1/1274	23/18639	0.0434782608695652	0.636099924919801	0.803949807858916	0.944294494144632
GO:0031681	G-protein beta-subunit binding	1/1274	23/18639	0.0434782608695652	0.636099924919801	0.803949807858916	0.944294494144632
GO:0042171	lysophosphatidic acid acyltransferase activity	1/1274	23/18639	0.0434782608695652	0.636099924919801	0.803949807858916	0.944294494144632
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/1274	23/18639	0.0434782608695652	0.636099924919801	0.803949807858916	0.944294494144632
GO:0070577	lysine-acetylated histone binding	1/1274	23/18639	0.0434782608695652	0.636099924919801	0.803949807858916	0.944294494144632
GO:0071617	lysophospholipid acyltransferase activity	1/1274	23/18639	0.0434782608695652	0.636099924919801	0.803949807858916	0.944294494144632
GO:0030971	receptor tyrosine kinase binding	4/1274	81/18639	0.0493827160493827	0.722483865341008	0.812926268631569	0.946790275422657
GO:0061135	endopeptidase regulator activity	10/1274	184/18639	0.0543478260869565	0.795124906149751	0.815120171871633	0.946790275422657
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0005540	hyaluronic acid binding	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0030552	cAMP binding	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0048027	mRNA 5'-UTR binding	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0050431	transforming growth factor beta binding	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0140033	acetylation-dependent protein binding	1/1274	24/18639	0.0416666666666667	0.609595761381476	0.817366650617174	0.946790275422657
GO:0030414	peptidase inhibitor activity	9/1274	169/18639	0.0532544378698225	0.779128310404726	0.823988396479593	0.95344729528955
GO:0003707	nuclear steroid receptor activity	1/1274	25/18639	0.04	0.585211930926217	0.829865973051433	0.956681977355227
GO:0017025	TBP-class protein binding	1/1274	25/18639	0.04	0.585211930926217	0.829865973051433	0.956681977355227
GO:0019211	phosphatase activator activity	1/1274	25/18639	0.04	0.585211930926217	0.829865973051433	0.956681977355227
GO:0019843	rRNA binding	3/1274	65/18639	0.0461538461538462	0.675244535684096	0.83029463355784	0.956681977355227
GO:0004180	carboxypeptidase activity	2/1274	46/18639	0.0434782608695652	0.636099924919801	0.831864596636686	0.957459725706262
GO:0004857	enzyme inhibitor activity	24/1274	416/18639	0.0576923076923077	0.84405566960512	0.83368644414295	0.957459725706262
GO:0032182	ubiquitin-like protein binding	6/1274	120/18639	0.05	0.731514913657771	0.836970704475464	0.957459725706262
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/1274	26/18639	0.0384615384615385	0.562703779736747	0.841510474519815	0.957459725706262
GO:0005160	transforming growth factor beta receptor binding	1/1274	26/18639	0.0384615384615385	0.562703779736747	0.841510474519815	0.957459725706262
GO:0005227	calcium-activated cation channel activity	1/1274	26/18639	0.0384615384615385	0.562703779736747	0.841510474519815	0.957459725706262
GO:0008066	glutamate receptor activity	1/1274	26/18639	0.0384615384615385	0.562703779736747	0.841510474519815	0.957459725706262
GO:0019865	immunoglobulin binding	1/1274	26/18639	0.0384615384615385	0.562703779736747	0.841510474519815	0.957459725706262
GO:0030247	polysaccharide binding	1/1274	26/18639	0.0384615384615385	0.562703779736747	0.841510474519815	0.957459725706262
GO:0030507	spectrin binding	1/1274	26/18639	0.0384615384615385	0.562703779736747	0.841510474519815	0.957459725706262
GO:0043548	phosphatidylinositol 3-kinase binding	1/1274	26/18639	0.0384615384615385	0.562703779736747	0.841510474519815	0.957459725706262
GO:0070006	metalloaminopeptidase activity	1/1274	26/18639	0.0384615384615385	0.562703779736747	0.841510474519815	0.957459725706262
GO:0140767	enzyme-substrate adaptor activity	7/1274	139/18639	0.0503597122302158	0.73677761087833	0.845471925301466	0.95887855327607
GO:0016209	antioxidant activity	4/1274	86/18639	0.0465116279069767	0.680478989449089	0.847745567874797	0.95887855327607
GO:1901681	sulfur compound binding	15/1274	275/18639	0.0545454545454545	0.798016269444841	0.850544305191206	0.95887855327607
GO:0008266	poly(U) RNA binding	1/1274	27/18639	0.037037037037037	0.541862899005756	0.852358572916729	0.95887855327607
GO:0008320	protein transmembrane transporter activity	1/1274	27/18639	0.037037037037037	0.541862899005756	0.852358572916729	0.95887855327607
GO:0023026	MHC class II protein complex binding	1/1274	27/18639	0.037037037037037	0.541862899005756	0.852358572916729	0.95887855327607
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/1274	27/18639	0.037037037037037	0.541862899005756	0.852358572916729	0.95887855327607
GO:0003777	microtubule motor activity	3/1274	68/18639	0.0441176470588235	0.645454335580386	0.852434236811479	0.95887855327607
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	3/1274	68/18639	0.0441176470588235	0.645454335580386	0.852434236811479	0.95887855327607
GO:0030145	manganese ion binding	3/1274	68/18639	0.0441176470588235	0.645454335580386	0.852434236811479	0.95887855327607
GO:0140223	general transcription initiation factor activity	3/1274	68/18639	0.0441176470588235	0.645454335580386	0.852434236811479	0.95887855327607
GO:0000149	SNARE binding	5/1274	106/18639	0.0471698113207547	0.690108409111104	0.858258694023752	0.961649507702845
GO:0008527	taste receptor activity	1/1274	28/18639	0.0357142857142857	0.522510652612693	0.862464696820882	0.961649507702845
GO:0016866	intramolecular transferase activity	1/1274	28/18639	0.0357142857142857	0.522510652612693	0.862464696820882	0.961649507702845
GO:0019789	SUMO transferase activity	1/1274	28/18639	0.0357142857142857	0.522510652612693	0.862464696820882	0.961649507702845
GO:0045499	chemorepellent activity	1/1274	28/18639	0.0357142857142857	0.522510652612693	0.862464696820882	0.961649507702845
GO:0046625	sphingolipid binding	1/1274	28/18639	0.0357142857142857	0.522510652612693	0.862464696820882	0.961649507702845
GO:0051393	alpha-actinin binding	1/1274	28/18639	0.0357142857142857	0.522510652612693	0.862464696820882	0.961649507702845
GO:0051537	2 iron, 2 sulfur cluster binding	1/1274	28/18639	0.0357142857142857	0.522510652612693	0.862464696820882	0.961649507702845
GO:0099106	ion channel regulator activity	8/1274	160/18639	0.05	0.731514913657771	0.86283781516824	0.961649507702845
GO:0106222	lncRNA binding	1/1274	29/18639	0.0344827586206897	0.504493043901911	0.871879557723047	0.969089548709914
GO:0005048	signal sequence binding	2/1274	51/18639	0.0392156862745098	0.573737187182565	0.872180593838923	0.969089548709914
GO:0016597	amino acid binding	2/1274	51/18639	0.0392156862745098	0.573737187182565	0.872180593838923	0.969089548709914
GO:0016853	isomerase activity	9/1274	180/18639	0.05	0.731514913657771	0.873938929496548	0.970054412577635
GO:0008187	poly-pyrimidine tract binding	1/1274	30/18639	0.0333333333333333	0.487676609105181	0.880650403690851	0.974526842662972
GO:0022839	monoatomic ion-gated channel activity	1/1274	30/18639	0.0333333333333333	0.487676609105181	0.880650403690851	0.974526842662972
GO:0048019	receptor antagonist activity	1/1274	30/18639	0.0333333333333333	0.487676609105181	0.880650403690851	0.974526842662972
GO:0015085	calcium ion transmembrane transporter activity	7/1274	147/18639	0.0476190476190476	0.696680870150258	0.882523396070912	0.975609028110846
GO:0046873	metal ion transmembrane transporter activity	25/1274	450/18639	0.0555555555555556	0.812794348508634	0.88416292830378	0.976431197417548
GO:0005200	structural constituent of cytoskeleton	5/1274	112/18639	0.0446428571428571	0.653138315765867	0.888195492515991	0.976628194306084
GO:0005184	neuropeptide hormone activity	1/1274	31/18639	0.032258064516129	0.471945105585659	0.888821255735446	0.976628194306084
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/1274	31/18639	0.032258064516129	0.471945105585659	0.888821255735446	0.976628194306084
GO:0008327	methyl-CpG binding	1/1274	31/18639	0.032258064516129	0.471945105585659	0.888821255735446	0.976628194306084
GO:0072349	modified amino acid transmembrane transporter activity	1/1274	31/18639	0.032258064516129	0.471945105585659	0.888821255735446	0.976628194306084
GO:0005262	calcium channel activity	6/1274	131/18639	0.0458015267175573	0.67008999724376	0.8908469408069	0.977868243181794
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/1274	54/18639	0.037037037037037	0.541862899005756	0.891890749740157	0.978029091767375
GO:0016247	channel regulator activity	8/1274	168/18639	0.0476190476190476	0.696680870150258	0.894804337371258	0.979070250084264
GO:0030515	snoRNA binding	1/1274	32/18639	0.03125	0.457196821036107	0.896433128058803	0.979070250084264
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/1274	32/18639	0.03125	0.457196821036107	0.896433128058803	0.979070250084264
GO:0160041	neuropeptide activity	1/1274	32/18639	0.03125	0.457196821036107	0.896433128058803	0.979070250084264
GO:0008374	O-acyltransferase activity	2/1274	55/18639	0.0363636363636364	0.532010846296561	0.897807025104804	0.979589246610847
GO:0017022	myosin binding	3/1274	76/18639	0.0394736842105263	0.577511773940345	0.899561965442448	0.980522542332268
GO:0141108	transporter regulator activity	8/1274	170/18639	0.0470588235294118	0.688484624619078	0.901742380185286	0.981917277124837
GO:0008017	microtubule binding	14/1274	276/18639	0.0507246376811594	0.742116579073101	0.90609468759991	0.984168540967118
GO:0019208	phosphatase regulator activity	5/1274	117/18639	0.0427350427350427	0.625226421929719	0.908827739121742	0.984168540967118
GO:0019838	growth factor binding	6/1274	136/18639	0.0441176470588235	0.645454335580386	0.909829055319521	0.984168540967118
GO:0015020	glucuronosyltransferase activity	1/1274	34/18639	0.0294117647058824	0.430302890386924	0.910130173665005	0.984168540967118
GO:0015035	protein-disulfide reductase activity	1/1274	34/18639	0.0294117647058824	0.430302890386924	0.910130173665005	0.984168540967118
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/1274	34/18639	0.0294117647058824	0.430302890386924	0.910130173665005	0.984168540967118
GO:0090482	vitamin transmembrane transporter activity	1/1274	34/18639	0.0294117647058824	0.430302890386924	0.910130173665005	0.984168540967118
GO:0022853	active monoatomic ion transmembrane transporter activity	5/1274	118/18639	0.0423728813559322	0.619927892930314	0.91252967751971	0.985785280967774
GO:0005154	epidermal growth factor receptor binding	1/1274	35/18639	0.0285714285714286	0.418008522090155	0.916284119311379	0.986906808349212
GO:0016229	steroid dehydrogenase activity	1/1274	35/18639	0.0285714285714286	0.418008522090155	0.916284119311379	0.986906808349212
GO:0061631	ubiquitin conjugating enzyme activity	1/1274	35/18639	0.0285714285714286	0.418008522090155	0.916284119311379	0.986906808349212
GO:0004252	serine-type endopeptidase activity	8/1274	176/18639	0.0454545454545455	0.665013557870701	0.920276768755867	0.989114617535931
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/1274	36/18639	0.0277777777777778	0.406397174254317	0.922016974181154	0.989114617535931
GO:0005484	SNAP receptor activity	1/1274	36/18639	0.0277777777777778	0.406397174254317	0.922016974181154	0.989114617535931
GO:0046982	protein heterodimerization activity	19/1274	369/18639	0.0514905149051491	0.753321591300685	0.924196697428262	0.989114617535931
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	5/1274	122/18639	0.040983606557377	0.599602388244074	0.926047945303083	0.989114617535931
GO:0022829	wide pore channel activity	1/1274	37/18639	0.027027027027027	0.395413466842038	0.927357530806065	0.989114617535931
GO:0030551	cyclic nucleotide binding	1/1274	37/18639	0.027027027027027	0.395413466842038	0.927357530806065	0.989114617535931
GO:0042805	actinin binding	1/1274	37/18639	0.027027027027027	0.395413466842038	0.927357530806065	0.989114617535931
GO:0070001	aspartic-type peptidase activity	1/1274	37/18639	0.027027027027027	0.395413466842038	0.927357530806065	0.989114617535931
GO:0015026	coreceptor activity	2/1274	61/18639	0.0327868852459016	0.47968191059526	0.927408384515341	0.989114617535931
GO:0005109	frizzled binding	1/1274	38/18639	0.0263157894736842	0.385007849293564	0.93233261443971	0.993394476773494
GO:0019955	cytokine binding	6/1274	144/18639	0.0416666666666667	0.609595761381476	0.934260268533865	0.99367246863411
GO:0022824	transmitter-gated monoatomic ion channel activity	2/1274	63/18639	0.0317460317460317	0.464453913433505	0.935328397081281	0.99367246863411
GO:0022835	transmitter-gated channel activity	2/1274	63/18639	0.0317460317460317	0.464453913433505	0.935328397081281	0.99367246863411
GO:0004497	monooxygenase activity	4/1274	106/18639	0.0377358490566038	0.552086727288884	0.937263114939734	0.994758320627371
GO:0019888	protein phosphatase regulator activity	4/1274	107/18639	0.0373831775700935	0.546927038248801	0.940120999653955	0.9961167381243
GO:0015036	disulfide oxidoreductase activity	1/1274	40/18639	0.025	0.365757456828885	0.941284624099109	0.9961167381243
GO:0071855	neuropeptide receptor binding	1/1274	40/18639	0.025	0.365757456828885	0.941284624099109	0.9961167381243
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/1274	41/18639	0.024390243902439	0.356836543247693	0.945306527905643	0.998308462949491
GO:0140318	protein transporter activity	1/1274	41/18639	0.024390243902439	0.356836543247693	0.945306527905643	0.998308462949491
GO:0005201	extracellular matrix structural constituent	7/1274	168/18639	0.0416666666666667	0.609595761381476	0.946103341492499	0.998308462949491
GO:0050840	extracellular matrix binding	2/1274	67/18639	0.0298507462686567	0.436725321586729	0.948775863648656	0.999485915086539
GO:0042056	chemoattractant activity	1/1274	42/18639	0.0238095238095238	0.348340435075129	0.949053139554649	0.999485915086539
GO:0030246	carbohydrate binding	13/1274	280/18639	0.0464285714285714	0.679263848396501	0.950186819951855	0.999713932188728
GO:0008201	heparin binding	7/1274	172/18639	0.0406976744186047	0.595419115767953	0.953944587586935	0.999999999999908
GO:0001223	transcription coactivator binding	1/1274	44/18639	0.0227272727272727	0.33250677893535	0.955794517296684	0.999999999999908
GO:0030547	signaling receptor inhibitor activity	1/1274	44/18639	0.0227272727272727	0.33250677893535	0.955794517296684	0.999999999999908
GO:0016782	transferase activity, transferring sulphur-containing groups	2/1274	70/18639	0.0285714285714286	0.418008522090155	0.957064194783297	0.999999999999908
GO:0008236	serine-type peptidase activity	8/1274	194/18639	0.0412371134020619	0.6033112689961	0.958938773104512	0.999999999999908
GO:0099094	ligand-gated monoatomic cation channel activity	5/1274	136/18639	0.0367647058823529	0.537878612983655	0.959890334007319	0.999999999999908
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/1274	46/18639	0.0217391304347826	0.3180499624599	0.961644470967644	0.999999999999908
GO:0005125	cytokine activity	10/1274	234/18639	0.0427350427350427	0.625226421929719	0.962531119219134	0.999999999999908
GO:0004896	cytokine receptor activity	3/1274	96/18639	0.03125	0.457196821036107	0.963919839364049	0.999999999999908
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/1274	73/18639	0.0273972602739726	0.400830089675491	0.964059010795536	0.999999999999908
GO:0005504	fatty acid binding	1/1274	47/18639	0.0212765957446809	0.31128294198203	0.964272607577509	0.999999999999908
GO:0043495	protein-membrane adaptor activity	1/1274	47/18639	0.0212765957446809	0.31128294198203	0.964272607577509	0.999999999999908
GO:0099095	ligand-gated monoatomic anion channel activity	1/1274	47/18639	0.0212765957446809	0.31128294198203	0.964272607577509	0.999999999999908
GO:0017171	serine hydrolase activity	8/1274	198/18639	0.0404040404040404	0.591123162551734	0.964810364752357	0.999999999999908
GO:0008188	neuropeptide receptor activity	1/1274	48/18639	0.0208333333333333	0.304797880690738	0.966720794859472	0.999999999999908
GO:0038187	pattern recognition receptor activity	1/1274	48/18639	0.0208333333333333	0.304797880690738	0.966720794859472	0.999999999999908
GO:0020037	heme binding	5/1274	142/18639	0.0352112676056338	0.515151347646318	0.969462542326669	0.999999999999908
GO:0043130	ubiquitin binding	3/1274	100/18639	0.03	0.438908948194662	0.97085432697539	0.999999999999908
GO:0001664	G protein-coupled receptor binding	13/1274	297/18639	0.0437710437710438	0.640383426097712	0.971301227094157	0.999999999999908
GO:0015276	ligand-gated monoatomic ion channel activity	7/1274	186/18639	0.0376344086021505	0.550602623183268	0.973953995000356	0.999999999999908
GO:0022834	ligand-gated channel activity	7/1274	188/18639	0.0372340425531915	0.544745148468553	0.97604731957392	0.999999999999908
GO:0008146	sulfotransferase activity	1/1274	53/18639	0.0188679245283019	0.276043363644442	0.976665135349451	0.999999999999908
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/1274	53/18639	0.0188679245283019	0.276043363644442	0.976665135349451	0.999999999999908
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/1274	54/18639	0.0185185185185185	0.270931449502878	0.978264652059061	0.999999999999908
GO:0005254	chloride channel activity	2/1274	83/18639	0.0240963855421687	0.352537307786877	0.980299828246743	0.999999999999908
GO:0046906	tetrapyrrole binding	5/1274	152/18639	0.0328947368421053	0.481259811616954	0.980853868585605	0.999999999999908
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/1274	56/18639	0.0178571428571429	0.261255326306347	0.981142502499427	0.999999999999908
GO:0022832	voltage-gated channel activity	6/1274	175/18639	0.0342857142857143	0.501610226508186	0.98257465701805	0.999999999999908
GO:0015079	potassium ion transmembrane transporter activity	5/1274	160/18639	0.03125	0.457196821036107	0.986955201868837	0.999999999999908
GO:0070851	growth factor receptor binding	4/1274	139/18639	0.0287769784172662	0.42101577764476	0.987683301087233	0.999999999999908
GO:0005507	copper ion binding	1/1274	63/18639	0.0158730158730159	0.232226956716753	0.988530592473709	0.999999999999908
GO:0042277	peptide binding	9/1274	249/18639	0.036144578313253	0.528805961680316	0.990024908297048	0.999999999999908
GO:0016500	protein-hormone receptor activity	1/1274	67/18639	0.0149253731343284	0.218362660793364	0.991368086591836	0.999999999999908
GO:0030594	neurotransmitter receptor activity	2/1274	97/18639	0.0206185567010309	0.30165563449805	0.991664070893716	0.999999999999908
GO:0098960	postsynaptic neurotransmitter receptor activity	1/1274	69/18639	0.0144927536231884	0.2120333083066	0.992511759430537	0.999999999999908
GO:0005216	monoatomic ion channel activity	19/1274	448/18639	0.0424107142857143	0.620481399977573	0.992565692213098	0.999999999999908
GO:0005244	voltage-gated monoatomic ion channel activity	5/1274	173/18639	0.0289017341040462	0.422840990553625	0.993127927695004	0.999999999999908
GO:0022836	gated channel activity	12/1274	318/18639	0.0377358490566038	0.552086727288884	0.993214494197044	0.999999999999908
GO:0005518	collagen binding	1/1274	72/18639	0.0138888888888889	0.203198587127159	0.993949713526821	0.999999999999908
GO:0005539	glycosaminoglycan binding	8/1274	242/18639	0.0330578512396694	0.483646223905964	0.994392736606533	0.999999999999908
GO:0019199	transmembrane receptor protein kinase activity	1/1274	78/18639	0.0128205128205128	0.187567926578916	0.996050685596384	0.999999999999908
GO:0022843	voltage-gated monoatomic cation channel activity	3/1274	143/18639	0.020979020979021	0.306929334401862	0.997416318115945	0.999999999999908
GO:0008528	G protein-coupled peptide receptor activity	2/1274	122/18639	0.0163934426229508	0.23984095529763	0.99827545234628	0.999999999999908
GO:0042562	hormone binding	1/1274	94/18639	0.0106382978723404	0.155641470991015	0.998734661144875	0.999999999999908
GO:0001653	peptide receptor activity	2/1274	128/18639	0.015625	0.228598410518053	0.998825504269026	0.999999999999908
GO:0005261	monoatomic cation channel activity	11/1274	341/18639	0.032258064516129	0.471945105585659	0.998857682011476	0.999999999999908
GO:0005179	hormone activity	2/1274	132/18639	0.0151515151515152	0.2216711859569	0.999091837365597	0.999999999999908
GO:0003730	mRNA 3'-UTR binding	6/1274	262/18639	0.0229007633587786	0.33504499862188	0.999771176518213	0.999999999999908
GO:0005267	potassium channel activity	1/1274	124/18639	0.00806451612903226	0.117986276396415	0.999850660750422	0.999999999999908
GO:0003823	antigen binding	2/1274	174/18639	0.0114942528735632	0.168164347967304	0.999941545881699	0.999999999999908
GO:0008083	growth factor activity	1/1274	162/18639	0.00617283950617284	0.090310483167626	0.999990081963297	0.999999999999908
GO:0045182	translation regulator activity	5/1274	356/18639	0.0140449438202247	0.205481717319599	0.999999787929736	0.999999999999908
GO:0030371	translation repressor activity	2/1274	329/18639	0.0060790273556231	0.0889379834234372	0.999999998419231	0.999999999999908
GO:0004984	olfactory receptor activity	1/1274	419/18639	0.00238663484486874	0.0349171796495356	0.999999999999908	0.999999999999908