ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 44/950 175/18639 0.251428571428571 4.93302857142857 4.17575587851272e-19 4.0045498874937e-16 GO:0045296 cadherin binding 47/950 334/18639 0.140718562874251 2.76089820359281 2.49766547213094e-10 1.19763059388679e-07 GO:0140662 ATP-dependent protein folding chaperone 15/950 40/18639 0.375 7.3575 4.42341489648555e-10 1.41401829524321e-07 GO:0044183 protein folding chaperone 20/950 75/18639 0.266666666666667 5.232 6.39612725752595e-10 1.53347150999185e-07 GO:0051082 unfolded protein binding 25/950 121/18639 0.206611570247934 4.05371900826446 1.71486708103993e-09 3.28911506143459e-07 GO:0019843 rRNA binding 18/950 65/18639 0.276923076923077 5.43323076923077 2.35859727736507e-09 3.76982464832184e-07 GO:0015078 proton transmembrane transporter activity 29/950 185/18639 0.156756756756757 3.07556756756757 6.48210286264288e-08 8.88048092182074e-06 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 16/950 68/18639 0.235294117647059 4.61647058823529 2.2059136065095e-07 2.64433893580326e-05 GO:0031072 heat shock protein binding 21/950 131/18639 0.16030534351145 3.14519083969466 2.87118854368752e-06 0.00030594109037737 GO:0098631 cell adhesion mediator activity 15/950 76/18639 0.197368421052632 3.87236842105263 5.57795898639305e-06 0.000532440886030653 GO:0009055 electron transfer activity 19/950 116/18639 0.163793103448276 3.21362068965517 6.10724686792198e-06 0.000532440886030653 GO:0051087 protein-folding chaperone binding 20/950 134/18639 0.149253731343284 2.92835820895522 1.4779226613121e-05 0.00118110652683192 GO:0140416 transcription regulator inhibitor activity 9/950 33/18639 0.272727272727273 5.35090909090909 2.84413681557162e-05 0.00190671700544657 GO:0022853 active monoatomic ion transmembrane transporter activity 18/950 118/18639 0.152542372881356 2.9928813559322 2.89234285343956e-05 0.00190671700544657 GO:0008137 NADH dehydrogenase (ubiquinone) activity 10/950 41/18639 0.24390243902439 4.78536585365854 2.98235193761194e-05 0.00190671700544657 GO:0030159 signaling receptor complex adaptor activity 11/950 52/18639 0.211538461538462 4.15038461538462 5.01835186846357e-05 0.00300787465116035 GO:0003954 NADH dehydrogenase activity 10/950 44/18639 0.227272727272727 4.45909090909091 5.74386854393634e-05 0.00324021760802056 GO:0031625 ubiquitin protein ligase binding 32/950 302/18639 0.105960264900662 2.07894039735099 7.53033658629308e-05 0.00401199599236392 GO:0098632 cell-cell adhesion mediator activity 11/950 55/18639 0.2 3.924 8.64342407420041e-05 0.00436265457218852 GO:0016651 oxidoreductase activity, acting on NAD(P)H 14/950 88/18639 0.159090909090909 3.12136363636364 0.00013762748478474 0.00623509830677115 GO:0048027 mRNA 5'-UTR binding 7/950 24/18639 0.291666666666667 5.7225 0.000140840656011936 0.00623509830677115 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 11/950 58/18639 0.189655172413793 3.72103448275862 0.000143036666057315 0.00623509830677115 GO:0060590 ATPase regulator activity 10/950 49/18639 0.204081632653061 4.00408163265306 0.000150953777001997 0.00629411618021372 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 6/950 18/18639 0.333333333333333 6.54 0.00018870745424627 0.00723881794488691 GO:0098641 cadherin binding involved in cell-cell adhesion 6/950 18/18639 0.333333333333333 6.54 0.00018870745424627 0.00723881794488691 GO:0044389 ubiquitin-like protein ligase binding 32/950 322/18639 0.0993788819875776 1.94981366459627 0.000247000909491108 0.0091105335462297 GO:0015399 primary active transmembrane transporter activity 20/950 166/18639 0.120481927710843 2.36385542168675 0.000310473253284981 0.0106423679694145 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 5/950 13/18639 0.384615384615385 7.54615384615385 0.000310726072099692 0.0106423679694145 GO:0045505 dynein intermediate chain binding 8/950 36/18639 0.222222222222222 4.36 0.000373604126651377 0.012069377143943 GO:0004857 enzyme inhibitor activity 38/950 416/18639 0.0913461538461538 1.79221153846154 0.000377561328799051 0.012069377143943 GO:0016209 antioxidant activity 13/950 86/18639 0.151162790697674 2.96581395348837 0.000395782027794469 0.0122437085372547 GO:0051015 actin filament binding 23/950 209/18639 0.110047846889952 2.15913875598086 0.000432745201545021 0.0129688327588024 GO:0004601 peroxidase activity 10/950 57/18639 0.175438596491228 3.44210526315789 0.000548536355701526 0.0159407989429625 GO:0004129 cytochrome-c oxidase activity 5/950 15/18639 0.333333333333333 6.54 0.000665668898001594 0.018775778623045 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 10/950 59/18639 0.169491525423729 3.32542372881356 0.000727952417272877 0.0199458962332768 GO:0004602 glutathione peroxidase activity 6/950 23/18639 0.260869565217391 5.11826086956522 0.000824369610062025 0.0219602904458189 GO:0035591 signaling adaptor activity 16/950 129/18639 0.124031007751938 2.43348837209302 0.000873050824513371 0.0226285335326574 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/950 16/18639 0.3125 6.13125 0.000927844632455012 0.0231491200939559 GO:0017080 sodium channel regulator activity 8/950 41/18639 0.195121951219512 3.82829268292683 0.000941413643028445 0.0231491200939559 GO:0005525 GTP binding 34/950 378/18639 0.0899470899470899 1.7647619047619 0.000980298217952539 0.0235026497754121 GO:0003779 actin binding 38/950 443/18639 0.0857787810383747 1.68297968397291 0.00123242162593436 0.0288266424212452 GO:0032794 GTPase activating protein binding 4/950 11/18639 0.363636363636364 7.13454545454545 0.001658618101425 0.0370633262215838 GO:0043022 ribosome binding 14/950 112/18639 0.125 2.4525 0.00166185925706788 0.0370633262215838 GO:0043021 ribonucleoprotein complex binding 19/950 177/18639 0.107344632768362 2.10610169491525 0.00176272009170109 0.0384192856350305 GO:0001671 ATPase activator activity 6/950 27/18639 0.222222222222222 4.36 0.00203062839744838 0.042334187677239 GO:0015252 proton channel activity 6/950 27/18639 0.222222222222222 4.36 0.00203062839744838 0.042334187677239 GO:0004859 phospholipase inhibitor activity 4/950 12/18639 0.333333333333333 6.54 0.00238813881360081 0.0482258702381848 GO:0097718 disordered domain specific binding 6/950 28/18639 0.214285714285714 4.20428571428571 0.00247452652987025 0.0482258702381848 GO:0019001 guanyl nucleotide binding 34/950 400/18639 0.085 1.6677 0.00251438322409723 0.0482258702381848 GO:0032561 guanyl ribonucleotide binding 34/950 400/18639 0.085 1.6677 0.00251438322409723 0.0482258702381848 GO:0043024 ribosomal small subunit binding 5/950 20/18639 0.25 4.905 0.00277876970262669 0.0522517675454705 GO:0070182 DNA polymerase binding 5/950 21/18639 0.238095238095238 4.67142857142857 0.00349599993348681 0.064474306465651 GO:0044548 S100 protein binding 4/950 14/18639 0.285714285714286 5.60571428571429 0.00445075485029652 0.0805334698383842 GO:0005200 structural constituent of cytoskeleton 13/950 112/18639 0.116071428571429 2.27732142857143 0.00459181861379498 0.0815472972338776 GO:0099186 structural constituent of postsynapse 5/950 23/18639 0.217391304347826 4.26521739130435 0.00531275585648054 0.0926351430248152 GO:0000774 adenyl-nucleotide exchange factor activity 4/950 15/18639 0.266666666666667 5.232 0.00582714974204012 0.0963489069416634 GO:0031386 protein tag activity 4/950 15/18639 0.266666666666667 5.232 0.00582714974204012 0.0963489069416634 GO:0141047 molecular tag activity 4/950 15/18639 0.266666666666667 5.232 0.00582714974204012 0.0963489069416634 GO:0061135 endopeptidase regulator activity 18/950 184/18639 0.0978260869565217 1.91934782608696 0.00615983169296672 0.100123365992459 GO:0048306 calcium-dependent protein binding 10/950 80/18639 0.125 2.4525 0.00730797097809993 0.113561605333024 GO:0005126 cytokine receptor binding 24/950 275/18639 0.0872727272727273 1.71229090909091 0.00737128385371553 0.113561605333024 GO:0030275 LRR domain binding 4/950 16/18639 0.25 4.905 0.00746025144523517 0.113561605333024 GO:0055102 lipase inhibitor activity 4/950 16/18639 0.25 4.905 0.00746025144523517 0.113561605333024 GO:0051219 phosphoprotein binding 11/950 93/18639 0.118279569892473 2.32064516129032 0.00761557793869075 0.114114675675069 GO:0001618 virus receptor activity 10/950 81/18639 0.123456790123457 2.42222222222222 0.00796730904168585 0.11754845186118 GO:0140272 exogenous protein binding 10/950 82/18639 0.121951219512195 2.39268292682927 0.00867149296531926 0.12599942051123 GO:0004867 serine-type endopeptidase inhibitor activity 11/950 95/18639 0.115789473684211 2.27178947368421 0.00890221915142862 0.127421315913732 GO:0008569 minus-end-directed microtubule motor activity 4/950 17/18639 0.235294117647059 4.61647058823529 0.00936812145262081 0.13095806750852 GO:0008135 translation factor activity, RNA binding 10/950 83/18639 0.120481927710843 2.36385542168675 0.00942242612939298 0.13095806750852 GO:0180051 translation factor activity 10/950 84/18639 0.119047619047619 2.33571428571429 0.0102220220969833 0.140041702728671 GO:0003924 GTPase activity 27/950 331/18639 0.081570996978852 1.60042296072508 0.011106099218183 0.143199173098467 GO:0019887 protein kinase regulator activity 22/950 255/18639 0.0862745098039216 1.69270588235294 0.0113443070681445 0.143199173098467 GO:0003774 cytoskeletal motor activity 15/950 153/18639 0.0980392156862745 1.92352941176471 0.0115249952593591 0.143199173098467 GO:0035254 glutamate receptor binding 7/950 49/18639 0.142857142857143 2.80285714285714 0.0115656950337482 0.143199173098467 GO:0003746 translation elongation factor activity 4/950 18/18639 0.222222222222222 4.36 0.0115671321245577 0.143199173098467 GO:0000146 microfilament motor activity 6/950 38/18639 0.157894736842105 3.09789473684211 0.011774283588648 0.143199173098467 GO:0061134 peptidase regulator activity 20/950 226/18639 0.0884955752212389 1.73628318584071 0.0118210968510025 0.143199173098467 GO:0016175 superoxide-generating NAD(P)H oxidase activity 3/950 10/18639 0.3 5.886 0.0120950292189529 0.143199173098467 GO:0030957 Tat protein binding 3/950 10/18639 0.3 5.886 0.0120950292189529 0.143199173098467 GO:0070513 death domain binding 3/950 10/18639 0.3 5.886 0.0120950292189529 0.143199173098467 GO:0098505 G-rich strand telomeric DNA binding 3/950 10/18639 0.3 5.886 0.0120950292189529 0.143199173098467 GO:0051959 dynein light intermediate chain binding 5/950 28/18639 0.178571428571429 3.50357142857143 0.0125773906915415 0.147094117965711 GO:0016776 phosphotransferase activity, phosphate group as acceptor 6/950 39/18639 0.153846153846154 3.01846153846154 0.0133308132336739 0.154027107121606 GO:0003725 double-stranded RNA binding 9/950 75/18639 0.12 2.3544 0.013753691369349 0.157021309800068 GO:0050145 nucleoside monophosphate kinase activity 4/950 19/18639 0.210526315789474 4.13052631578947 0.0140718857012605 0.158763981029515 GO:0030544 Hsp70 protein binding 7/950 51/18639 0.137254901960784 2.69294117647059 0.0142843564399445 0.159287184022171 GO:0043522 leucine zipper domain binding 3/950 11/18639 0.272727272727273 5.35090909090909 0.0160086833880258 0.172498060327154 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 3/950 11/18639 0.272727272727273 5.35090909090909 0.0160086833880258 0.172498060327154 GO:1990948 ubiquitin ligase inhibitor activity 3/950 11/18639 0.272727272727273 5.35090909090909 0.0160086833880258 0.172498060327154 GO:1990782 protein tyrosine kinase binding 12/950 117/18639 0.102564102564103 2.01230769230769 0.0161930962441118 0.172546436645592 GO:0098918 structural constituent of synapse 5/950 30/18639 0.166666666666667 3.27 0.0167751518765535 0.175791488352898 GO:0042169 SH2 domain binding 6/950 41/18639 0.146341463414634 2.87121951219512 0.0168642512288495 0.175791488352898 GO:0004866 endopeptidase inhibitor activity 15/950 161/18639 0.093167701863354 1.82795031055901 0.0176987714012467 0.182506685739737 GO:0046332 SMAD binding 9/950 79/18639 0.113924050632911 2.23518987341772 0.0188489182903802 0.190305483564863 GO:0051879 Hsp90 protein binding 6/950 42/18639 0.142857142857143 2.80285714285714 0.0188519509266549 0.190305483564863 GO:0070273 phosphatidylinositol-4-phosphate binding 5/950 31/18639 0.161290322580645 3.16451612903226 0.019184563372208 0.191645794520286 GO:0010314 phosphatidylinositol-5-phosphate binding 4/950 21/18639 0.19047619047619 3.73714285714286 0.0200479093520794 0.197063614514079 GO:0016423 tRNA (guanine) methyltransferase activity 3/950 12/18639 0.25 4.905 0.0205488649128341 0.197063614514079 GO:0035259 nuclear glucocorticoid receptor binding 3/950 12/18639 0.25 4.905 0.0205488649128341 0.197063614514079 GO:0043047 single-stranded telomeric DNA binding 3/950 12/18639 0.25 4.905 0.0205488649128341 0.197063614514079 GO:0048156 tau protein binding 6/950 43/18639 0.13953488372093 2.73767441860465 0.0209937265343816 0.199336472737346 GO:0019207 kinase regulator activity 23/950 287/18639 0.0801393728222996 1.57233449477352 0.0217444291794432 0.204440270422412 GO:0019205 nucleobase-containing compound kinase activity 6/950 44/18639 0.136363636363636 2.67545454545455 0.0232942846484448 0.216885621144258 GO:0030414 peptidase inhibitor activity 15/950 169/18639 0.0887573964497041 1.7414201183432 0.0261307154585877 0.240955347353708 GO:0004860 protein kinase inhibitor activity 9/950 84/18639 0.107142857142857 2.10214285714286 0.0269861761090929 0.246473741796382 GO:0140103 catalytic activity, acting on a glycoprotein 4/950 23/18639 0.173913043478261 3.41217391304348 0.0273763681187653 0.247678651187698 GO:0022804 active transmembrane transporter activity 33/950 457/18639 0.0722100656455142 1.41676148796499 0.0282141299322862 0.252872435561332 GO:0042379 chemokine receptor binding 8/950 72/18639 0.111111111111111 2.18 0.0297017612077294 0.263740638872338 GO:0001784 phosphotyrosine residue binding 6/950 47/18639 0.127659574468085 2.50468085106383 0.031190979335363 0.272328554792996 GO:0032036 myosin heavy chain binding 3/950 14/18639 0.214285714285714 4.20428571428571 0.0315208233389182 0.272328554792996 GO:0098847 sequence-specific single stranded DNA binding 3/950 14/18639 0.214285714285714 4.20428571428571 0.0315208233389182 0.272328554792996 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 5/950 36/18639 0.138888888888889 2.725 0.0345931166043089 0.291007007223967 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 5/950 36/18639 0.138888888888889 2.725 0.0345931166043089 0.291007007223967 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 5/950 36/18639 0.138888888888889 2.725 0.0345931166043089 0.291007007223967 GO:0005178 integrin binding 14/950 161/18639 0.0869565217391304 1.70608695652174 0.0358946097842394 0.299329832896396 GO:0031005 filamin binding 3/950 15/18639 0.2 3.924 0.0379442417381377 0.308377354465034 GO:0055105 ubiquitin-protein transferase inhibitor activity 3/950 15/18639 0.2 3.924 0.0379442417381377 0.308377354465034 GO:0140776 protein-containing complex destabilizing activity 3/950 15/18639 0.2 3.924 0.0379442417381377 0.308377354465034 GO:0023023 MHC protein complex binding 5/950 37/18639 0.135135135135135 2.65135135135135 0.0383810577906873 0.309306171607303 GO:0019210 kinase inhibitor activity 9/950 90/18639 0.1 1.962 0.0396830360267061 0.31713359624676 GO:0140297 DNA-binding transcription factor binding 34/950 488/18639 0.069672131147541 1.36696721311475 0.0406241229515506 0.321971354632538 GO:0042162 telomeric DNA binding 5/950 38/18639 0.131578947368421 2.58157894736842 0.0424123872152387 0.333389174913229 GO:0003743 translation initiation factor activity 6/950 51/18639 0.117647058823529 2.30823529411765 0.0441708272117324 0.339644640715955 GO:0003697 single-stranded DNA binding 11/950 121/18639 0.0909090909090909 1.78363636363636 0.0448119386208924 0.339644640715955 GO:0017070 U6 snRNA binding 3/950 16/18639 0.1875 3.67875 0.0449790087288075 0.339644640715955 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 3/950 16/18639 0.1875 3.67875 0.0449790087288075 0.339644640715955 GO:0070411 I-SMAD binding 3/950 16/18639 0.1875 3.67875 0.0449790087288075 0.339644640715955 GO:0004364 glutathione transferase activity 4/950 27/18639 0.148148148148148 2.90666666666667 0.0462675897024303 0.341312450189467 GO:0023026 MHC class II protein complex binding 4/950 27/18639 0.148148148148148 2.90666666666667 0.0462675897024303 0.341312450189467 GO:0035255 ionotropic glutamate receptor binding 4/950 27/18639 0.148148148148148 2.90666666666667 0.0462675897024303 0.341312450189467 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/950 39/18639 0.128205128205128 2.51538461538461 0.0466890892713512 0.34179264588722 GO:0000049 tRNA binding 8/950 80/18639 0.1 1.962 0.0507129212925491 0.368437056966323 GO:0140296 general transcription initiation factor binding 6/950 53/18639 0.113207547169811 2.2211320754717 0.0517570733302054 0.373195739275691 GO:0005125 cytokine activity 18/950 234/18639 0.0769230769230769 1.50923076923077 0.0541739555460209 0.387707637079359 GO:0004896 cytokine receptor activity 9/950 96/18639 0.09375 1.839375 0.055918248182885 0.396693946811449 GO:0016887 ATP hydrolysis activity 29/950 417/18639 0.0695443645083933 1.36446043165468 0.0562569100796215 0.396693946811449 GO:0003785 actin monomer binding 4/950 29/18639 0.137931034482759 2.70620689655172 0.0578517974575418 0.404962582202793 GO:0070064 proline-rich region binding 3/950 18/18639 0.166666666666667 3.27 0.0608184693492483 0.417855034949941 GO:0016859 cis-trans isomerase activity 5/950 42/18639 0.119047619047619 2.33571428571429 0.0610007350291885 0.417855034949941 GO:0035198 miRNA binding 5/950 42/18639 0.119047619047619 2.33571428571429 0.0610007350291885 0.417855034949941 GO:0001965 G-protein alpha-subunit binding 4/950 30/18639 0.133333333333333 2.616 0.0641712813930785 0.431339616411049 GO:0019903 protein phosphatase binding 12/950 144/18639 0.0833333333333333 1.635 0.0642898295392858 0.431339616411049 GO:0005516 calmodulin binding 16/950 207/18639 0.0772946859903382 1.51652173913043 0.0643186289330344 0.431339616411049 GO:0097110 scaffold protein binding 7/950 70/18639 0.1 1.962 0.0651357036967326 0.433785693369212 GO:0005164 tumor necrosis factor receptor binding 4/950 31/18639 0.129032258064516 2.53161290322581 0.0708359803591334 0.468494518375234 GO:0043425 bHLH transcription factor binding 4/950 32/18639 0.125 2.4525 0.0778396295332451 0.511289073440973 GO:0042288 MHC class I protein binding 3/950 20/18639 0.15 2.943 0.0788813871507155 0.511965069506375 GO:0045309 protein phosphorylated amino acid binding 6/950 59/18639 0.101694915254237 1.99525423728814 0.0790102505598994 0.511965069506375 GO:0030291 protein serine/threonine kinase inhibitor activity 5/950 46/18639 0.108695652173913 2.13260869565217 0.083518132888475 0.523635393954357 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 24/950 349/18639 0.0687679083094556 1.34922636103152 0.0844972839522524 0.523635393954357 GO:0016247 channel regulator activity 13/950 168/18639 0.0773809523809524 1.51821428571429 0.0882245721062226 0.523635393954357 GO:0008373 sialyltransferase activity 3/950 21/18639 0.142857142857143 2.80285714285714 0.0886869667838215 0.523635393954357 GO:0005381 iron ion transmembrane transporter activity 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0005528 FK506 binding 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0008140 cAMP response element binding protein binding 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0016783 sulfurtransferase activity 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0019531 oxalate transmembrane transporter activity 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0019911 structural constituent of myelin sheath 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0031720 haptoglobin binding 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0035256 G protein-coupled glutamate receptor binding 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0047429 nucleoside triphosphate diphosphatase activity 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:1905394 retromer complex binding 2/950 10/18639 0.2 3.924 0.0890016363029824 0.523635393954357 GO:0008175 tRNA methyltransferase activity 4/950 34/18639 0.117647058823529 2.30823529411765 0.0928334202412582 0.53955909097798 GO:0019825 oxygen binding 4/950 34/18639 0.117647058823529 2.30823529411765 0.0928334202412582 0.53955909097798 GO:0141108 transporter regulator activity 13/950 170/18639 0.0764705882352941 1.50035294117647 0.0945840639905166 0.546422393776539 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 5/950 48/18639 0.104166666666667 2.04375 0.0962103750673663 0.552489519099427 GO:0008970 phospholipase A1 activity 3/950 22/18639 0.136363636363636 2.67545454545455 0.0989734534086186 0.55832671658156 GO:0061133 endopeptidase activator activity 3/950 22/18639 0.136363636363636 2.67545454545455 0.0989734534086186 0.55832671658156 GO:0140517 protein-RNA adaptor activity 3/950 22/18639 0.136363636363636 2.67545454545455 0.0989734534086186 0.55832671658156 GO:0002162 dystroglycan binding 2/950 11/18639 0.181818181818182 3.56727272727273 0.105222292506306 0.57010270346637 GO:0008271 secondary active sulfate transmembrane transporter activity 2/950 11/18639 0.181818181818182 3.56727272727273 0.105222292506306 0.57010270346637 GO:0031731 CCR6 chemokine receptor binding 2/950 11/18639 0.181818181818182 3.56727272727273 0.105222292506306 0.57010270346637 GO:0042608 T cell receptor binding 2/950 11/18639 0.181818181818182 3.56727272727273 0.105222292506306 0.57010270346637 GO:0045294 alpha-catenin binding 2/950 11/18639 0.181818181818182 3.56727272727273 0.105222292506306 0.57010270346637 GO:0048185 activin binding 2/950 11/18639 0.181818181818182 3.56727272727273 0.105222292506306 0.57010270346637 GO:0070990 snRNP binding 2/950 11/18639 0.181818181818182 3.56727272727273 0.105222292506306 0.57010270346637 GO:0019902 phosphatase binding 14/950 190/18639 0.0736842105263158 1.44568421052632 0.106750459774151 0.575133095075339 GO:0048020 CCR chemokine receptor binding 5/950 50/18639 0.1 1.962 0.109818743837618 0.588358521454055 GO:0099106 ion channel regulator activity 12/950 160/18639 0.075 1.4715 0.116775670672916 0.603858463535956 GO:0030971 receptor tyrosine kinase binding 7/950 81/18639 0.0864197530864197 1.69555555555556 0.118542369545134 0.603858463535956 GO:0005025 transforming growth factor beta receptor activity, type I 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0005026 transforming growth factor beta receptor activity, type II 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0005527 macrolide binding 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0016208 AMP binding 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0016361 activin receptor activity, type I 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0016362 activin receptor activity, type II 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0017002 activin receptor activity 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0017166 vinculin binding 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0031543 peptidyl-proline dioxygenase activity 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0045295 gamma-catenin binding 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0097371 MDM2/MDM4 family protein binding 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/950 12/18639 0.166666666666667 3.27 0.122156978025 0.603858463535956 GO:0001664 G protein-coupled receptor binding 20/950 297/18639 0.0673400673400673 1.32121212121212 0.124928618187641 0.614392537651014 GO:0015631 tubulin binding 25/950 385/18639 0.0649350649350649 1.27402597402597 0.128275360066805 0.62763301175544 GO:0005544 calcium-dependent phospholipid binding 5/950 53/18639 0.0943396226415094 1.85094339622642 0.131860611544819 0.638827624709585 GO:0003777 microtubule motor activity 6/950 68/18639 0.0882352941176471 1.73117647058824 0.132230914730751 0.638827624709585 GO:0017124 SH3 domain binding 9/950 115/18639 0.0782608695652174 1.53547826086957 0.132561728172271 0.638827624709585 GO:0002039 p53 binding 6/950 69/18639 0.0869565217391304 1.70608695652174 0.138997681882594 0.656684449207869 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/950 13/18639 0.153846153846154 3.01846153846154 0.139690956870079 0.656684449207869 GO:0061459 L-arginine transmembrane transporter activity 2/950 13/18639 0.153846153846154 3.01846153846154 0.139690956870079 0.656684449207869 GO:0070123 transforming growth factor beta receptor activity, type III 2/950 13/18639 0.153846153846154 3.01846153846154 0.139690956870079 0.656684449207869 GO:0140666 annealing activity 2/950 13/18639 0.153846153846154 3.01846153846154 0.139690956870079 0.656684449207869 GO:0008157 protein phosphatase 1 binding 3/950 26/18639 0.115384615384615 2.26384615384615 0.144361685520126 0.675331006896588 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 7/950 86/18639 0.0813953488372093 1.59697674418605 0.148543777236201 0.691521759075325 GO:1901981 phosphatidylinositol phosphate binding 13/950 185/18639 0.0702702702702703 1.3787027027027 0.150936407863508 0.699265773628523 GO:0042287 MHC protein binding 4/950 41/18639 0.0975609756097561 1.91414634146341 0.154629338796671 0.706788881531788 GO:0002020 protease binding 10/950 136/18639 0.0735294117647059 1.44264705882353 0.156432733999584 0.706788881531788 GO:0044325 transmembrane transporter binding 10/950 136/18639 0.0735294117647059 1.44264705882353 0.156432733999584 0.706788881531788 GO:0005385 zinc ion transmembrane transporter activity 3/950 27/18639 0.111111111111111 2.18 0.156623447497338 0.706788881531788 GO:0005344 oxygen carrier activity 2/950 14/18639 0.142857142857143 2.80285714285714 0.157719312458605 0.706788881531788 GO:0008195 phosphatidate phosphatase activity 2/950 14/18639 0.142857142857143 2.80285714285714 0.157719312458605 0.706788881531788 GO:0098821 BMP receptor activity 2/950 14/18639 0.142857142857143 2.80285714285714 0.157719312458605 0.706788881531788 GO:0003714 transcription corepressor activity 14/950 204/18639 0.0686274509803922 1.34647058823529 0.159432412316013 0.711142713539798 GO:0016922 nuclear receptor binding 10/950 137/18639 0.072992700729927 1.43211678832117 0.161589278458557 0.717426472415538 GO:0016504 peptidase activator activity 5/950 57/18639 0.087719298245614 1.72105263157895 0.164033030502422 0.72492016705909 GO:0043539 protein serine/threonine kinase activator activity 6/950 73/18639 0.0821917808219178 1.61260273972603 0.167599265651657 0.737283008073116 GO:0008201 heparin binding 12/950 172/18639 0.0697674418604651 1.36883720930233 0.168548148724758 0.738071573639466 GO:0008017 microtubule binding 18/950 276/18639 0.0652173913043478 1.2795652173913 0.170411287801297 0.74283829546111 GO:0061980 regulatory RNA binding 5/950 58/18639 0.0862068965517241 1.69137931034483 0.172526778636055 0.747452435011331 GO:0140375 immune receptor activity 11/950 156/18639 0.0705128205128205 1.38346153846154 0.173096342881072 0.747452435011331 GO:0008242 omega peptidase activity 2/950 15/18639 0.133333333333333 2.616 0.1761462464156 0.747452435011331 GO:0015116 sulfate transmembrane transporter activity 2/950 15/18639 0.133333333333333 2.616 0.1761462464156 0.747452435011331 GO:0016846 carbon-sulfur lyase activity 2/950 15/18639 0.133333333333333 2.616 0.1761462464156 0.747452435011331 GO:0017081 chloride channel regulator activity 2/950 15/18639 0.133333333333333 2.616 0.1761462464156 0.747452435011331 GO:0001786 phosphatidylserine binding 5/950 59/18639 0.0847457627118644 1.66271186440678 0.181185716420884 0.752481552703145 GO:0004879 nuclear receptor activity 5/950 59/18639 0.0847457627118644 1.66271186440678 0.181185716420884 0.752481552703145 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/950 29/18639 0.103448275862069 2.02965517241379 0.182039332875005 0.752481552703145 GO:0043236 laminin binding 3/950 29/18639 0.103448275862069 2.02965517241379 0.182039332875005 0.752481552703145 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/950 29/18639 0.103448275862069 2.02965517241379 0.182039332875005 0.752481552703145 GO:0097472 cyclin-dependent protein kinase activity 3/950 29/18639 0.103448275862069 2.02965517241379 0.182039332875005 0.752481552703145 GO:0098531 ligand-modulated transcription factor activity 5/950 60/18639 0.0833333333333333 1.635 0.1900019623376 0.773963559324003 GO:0005543 phospholipid binding 30/950 497/18639 0.0603621730382294 1.18430583501006 0.192160738116171 0.773963559324003 GO:0004708 MAP kinase kinase activity 2/950 16/18639 0.125 2.4525 0.194884423227999 0.773963559324003 GO:0005024 transforming growth factor beta receptor activity 2/950 16/18639 0.125 2.4525 0.194884423227999 0.773963559324003 GO:0005159 insulin-like growth factor receptor binding 2/950 16/18639 0.125 2.4525 0.194884423227999 0.773963559324003 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/950 16/18639 0.125 2.4525 0.194884423227999 0.773963559324003 GO:0022858 alanine transmembrane transporter activity 2/950 16/18639 0.125 2.4525 0.194884423227999 0.773963559324003 GO:0043023 ribosomal large subunit binding 2/950 16/18639 0.125 2.4525 0.194884423227999 0.773963559324003 GO:0008009 chemokine activity 4/950 45/18639 0.0888888888888889 1.744 0.195306758452981 0.773963559324003 GO:0046915 transition metal ion transmembrane transporter activity 4/950 45/18639 0.0888888888888889 1.744 0.195306758452981 0.773963559324003 GO:0019955 cytokine binding 10/950 144/18639 0.0694444444444444 1.3625 0.199902138057722 0.788914199166073 GO:1902936 phosphatidylinositol bisphosphate binding 8/950 111/18639 0.0720720720720721 1.41405405405405 0.205226278530542 0.806606561929467 GO:0015179 L-amino acid transmembrane transporter activity 5/950 62/18639 0.0806451612903226 1.58225806451613 0.208074110147246 0.807426493037718 GO:0016853 isomerase activity 12/950 180/18639 0.0666666666666667 1.308 0.208416630276871 0.807426493037718 GO:0005310 dicarboxylic acid transmembrane transporter activity 3/950 31/18639 0.0967741935483871 1.89870967741935 0.208453619041149 0.807426493037718 GO:0004550 nucleoside diphosphate kinase activity 2/950 17/18639 0.117647058823529 2.30823529411765 0.213854357905715 0.807426493037718 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/950 17/18639 0.117647058823529 2.30823529411765 0.213854357905715 0.807426493037718 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/950 17/18639 0.117647058823529 2.30823529411765 0.213854357905715 0.807426493037718 GO:0016018 cyclosporin A binding 2/950 17/18639 0.117647058823529 2.30823529411765 0.213854357905715 0.807426493037718 GO:0019198 transmembrane receptor protein phosphatase activity 2/950 17/18639 0.117647058823529 2.30823529411765 0.213854357905715 0.807426493037718 GO:0051787 misfolded protein binding 2/950 17/18639 0.117647058823529 2.30823529411765 0.213854357905715 0.807426493037718 GO:1990226 histone methyltransferase binding 2/950 17/18639 0.117647058823529 2.30823529411765 0.213854357905715 0.807426493037718 GO:0005507 copper ion binding 5/950 63/18639 0.0793650793650794 1.55714285714286 0.217313586135086 0.817269525896265 GO:0015106 bicarbonate transmembrane transporter activity 3/950 32/18639 0.09375 1.839375 0.221965411059208 0.831503239085079 GO:0019209 kinase activator activity 10/950 148/18639 0.0675675675675676 1.32567567567568 0.223392825789524 0.833594240981143 GO:0032266 phosphatidylinositol-3-phosphate binding 4/950 48/18639 0.0833333333333333 1.635 0.227722471729596 0.843137759895423 GO:0140693 molecular condensate scaffold activity 4/950 48/18639 0.0833333333333333 1.635 0.227722471729596 0.843137759895423 GO:0015101 organic cation transmembrane transporter activity 6/950 81/18639 0.0740740740740741 1.45333333333333 0.231166035521979 0.843137759895423 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/950 18/18639 0.111111111111111 2.18 0.232983843975273 0.843137759895423 GO:0008409 5'-3' exonuclease activity 2/950 18/18639 0.111111111111111 2.18 0.232983843975273 0.843137759895423 GO:0015172 acidic amino acid transmembrane transporter activity 2/950 18/18639 0.111111111111111 2.18 0.232983843975273 0.843137759895423 GO:0017075 syntaxin-1 binding 2/950 18/18639 0.111111111111111 2.18 0.232983843975273 0.843137759895423 GO:0034185 apolipoprotein binding 2/950 18/18639 0.111111111111111 2.18 0.232983843975273 0.843137759895423 GO:0019239 deaminase activity 3/950 33/18639 0.0909090909090909 1.78363636363636 0.235644463575725 0.84637842909783 GO:0030296 protein tyrosine kinase activator activity 3/950 33/18639 0.0909090909090909 1.78363636363636 0.235644463575725 0.84637842909783 GO:0016763 pentosyltransferase activity 4/950 49/18639 0.0816326530612245 1.60163265306122 0.23881759396009 0.854235109708634 GO:0015294 solute:monoatomic cation symporter activity 8/950 116/18639 0.0689655172413793 1.35310344827586 0.239613393651327 0.854235109708634 GO:0003712 transcription coregulator activity 29/950 495/18639 0.0585858585858586 1.14945454545455 0.244011114058716 0.866691327341885 GO:0030165 PDZ domain binding 6/950 83/18639 0.072289156626506 1.41831325301205 0.248134975066994 0.878086498484307 GO:0032813 tumor necrosis factor receptor superfamily binding 4/950 50/18639 0.08 1.5696 0.250034885275088 0.881556819775035 GO:0042577 lipid phosphatase activity 2/950 19/18639 0.105263157894737 2.06526315789474 0.252207419291982 0.882725967521939 GO:0070003 threonine-type peptidase activity 2/950 19/18639 0.105263157894737 2.06526315789474 0.252207419291982 0.882725967521939 GO:0008173 RNA methyltransferase activity 5/950 67/18639 0.0746268656716418 1.46417910447761 0.255432515492396 0.887535443323217 GO:0016500 protein-hormone receptor activity 5/950 67/18639 0.0746268656716418 1.46417910447761 0.255432515492396 0.887535443323217 GO:0019838 growth factor binding 9/950 136/18639 0.0661764705882353 1.29838235294118 0.257826508839529 0.889658270323882 GO:0005154 epidermal growth factor receptor binding 3/950 35/18639 0.0857142857142857 1.68171428571429 0.263401657022533 0.889658270323882 GO:0005343 organic acid:sodium symporter activity 3/950 35/18639 0.0857142857142857 1.68171428571429 0.263401657022533 0.889658270323882 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 28/950 484/18639 0.0578512396694215 1.13504132231405 0.270219006855596 0.889658270323882 GO:0001972 retinoic acid binding 2/950 20/18639 0.1 1.962 0.271465867307679 0.889658270323882 GO:0016505 peptidase activator activity involved in apoptotic process 2/950 20/18639 0.1 1.962 0.271465867307679 0.889658270323882 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/950 20/18639 0.1 1.962 0.271465867307679 0.889658270323882 GO:0031418 L-ascorbic acid binding 2/950 20/18639 0.1 1.962 0.271465867307679 0.889658270323882 GO:0015108 chloride transmembrane transporter activity 8/950 121/18639 0.0661157024793388 1.29719008264463 0.275773763588586 0.889658270323882 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/950 36/18639 0.0833333333333333 1.635 0.277430660419173 0.889658270323882 GO:0005484 SNAP receptor activity 3/950 36/18639 0.0833333333333333 1.635 0.277430660419173 0.889658270323882 GO:0055106 ubiquitin-protein transferase regulator activity 3/950 36/18639 0.0833333333333333 1.635 0.277430660419173 0.889658270323882 GO:0030295 protein kinase activator activity 9/950 139/18639 0.0647482014388489 1.27035971223022 0.278286316982249 0.889658270323882 GO:0035091 phosphatidylinositol binding 17/950 284/18639 0.0598591549295775 1.17443661971831 0.281631736312542 0.889658270323882 GO:0016860 intramolecular oxidoreductase activity 4/950 53/18639 0.0754716981132075 1.48075471698113 0.284286132281325 0.889658270323882 GO:0015174 basic amino acid transmembrane transporter activity 2/950 21/18639 0.0952380952380952 1.86857142857143 0.290705751573348 0.889658270323882 GO:0035613 RNA stem-loop binding 2/950 21/18639 0.0952380952380952 1.86857142857143 0.290705751573348 0.889658270323882 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/950 21/18639 0.0952380952380952 1.86857142857143 0.290705751573348 0.889658270323882 GO:0072542 protein phosphatase activator activity 2/950 21/18639 0.0952380952380952 1.86857142857143 0.290705751573348 0.889658270323882 GO:0140312 cargo adaptor activity 2/950 21/18639 0.0952380952380952 1.86857142857143 0.290705751573348 0.889658270323882 GO:0043394 proteoglycan binding 3/950 37/18639 0.0810810810810811 1.59081081081081 0.291528732872635 0.889658270323882 GO:0017069 snRNA binding 4/950 54/18639 0.0740740740740741 1.45333333333333 0.295859515196603 0.889658270323882 GO:0001216 DNA-binding transcription activator activity 28/950 491/18639 0.0570264765784114 1.11885947046843 0.29592487466842 0.889658270323882 GO:0008013 beta-catenin binding 7/950 106/18639 0.0660377358490566 1.29566037735849 0.295944777205374 0.889658270323882 GO:0020037 heme binding 9/950 142/18639 0.0633802816901408 1.24352112676056 0.299185011643899 0.889658270323882 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/950 89/18639 0.0674157303370786 1.32269662921348 0.30089621862993 0.889658270323882 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/950 89/18639 0.0674157303370786 1.32269662921348 0.30089621862993 0.889658270323882 GO:0043531 ADP binding 3/950 38/18639 0.0789473684210526 1.54894736842105 0.305673685579927 0.889658270323882 GO:0008093 cytoskeletal anchor activity 2/950 22/18639 0.0909090909090909 1.78363636363636 0.309878981389821 0.889658270323882 GO:0070034 telomerase RNA binding 2/950 22/18639 0.0909090909090909 1.78363636363636 0.309878981389821 0.889658270323882 GO:0140793 histone H2AXY142 phosphatase activity 6/950 90/18639 0.0666666666666667 1.308 0.309899180907466 0.889658270323882 GO:0072341 modified amino acid binding 6/950 91/18639 0.0659340659340659 1.29362637362637 0.318946596547848 0.889658270323882 GO:0031491 nucleosome binding 5/950 74/18639 0.0675675675675676 1.32567567567568 0.325320750109758 0.889658270323882 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 8/950 128/18639 0.0625 1.22625 0.328591323335023 0.889658270323882 GO:0005212 structural constituent of eye lens 2/950 23/18639 0.0869565217391304 1.70608695652174 0.328942406645794 0.889658270323882 GO:0005283 amino acid:sodium symporter activity 2/950 23/18639 0.0869565217391304 1.70608695652174 0.328942406645794 0.889658270323882 GO:0016493 C-C chemokine receptor activity 2/950 23/18639 0.0869565217391304 1.70608695652174 0.328942406645794 0.889658270323882 GO:0017134 fibroblast growth factor binding 2/950 23/18639 0.0869565217391304 1.70608695652174 0.328942406645794 0.889658270323882 GO:0031681 G-protein beta-subunit binding 2/950 23/18639 0.0869565217391304 1.70608695652174 0.328942406645794 0.889658270323882 GO:0043274 phospholipase binding 2/950 23/18639 0.0869565217391304 1.70608695652174 0.328942406645794 0.889658270323882 GO:0015144 carbohydrate transmembrane transporter activity 3/950 40/18639 0.075 1.4715 0.334020460734255 0.889658270323882 GO:0030331 nuclear estrogen receptor binding 3/950 40/18639 0.075 1.4715 0.334020460734255 0.889658270323882 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/950 40/18639 0.075 1.4715 0.334020460734255 0.889658270323882 GO:0017022 myosin binding 5/950 76/18639 0.0657894736842105 1.29078947368421 0.345713172276266 0.889658270323882 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0015149 hexose transmembrane transporter activity 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0015295 solute:proton symporter activity 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0019957 C-C chemokine binding 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0035035 histone acetyltransferase binding 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0050699 WW domain binding 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0055056 D-glucose transmembrane transporter activity 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0070300 phosphatidic acid binding 2/950 24/18639 0.0833333333333333 1.635 0.347857440001067 0.889658270323882 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/950 41/18639 0.0731707317073171 1.43560975609756 0.348182917729327 0.889658270323882 GO:0008509 monoatomic anion transmembrane transporter activity 9/950 149/18639 0.0604026845637584 1.18510067114094 0.349241286282038 0.889658270323882 GO:0005539 glycosaminoglycan binding 14/950 242/18639 0.0578512396694215 1.13504132231405 0.351746654958471 0.889658270323882 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 14/950 243/18639 0.0576131687242798 1.13037037037037 0.357434147400066 0.889658270323882 GO:0008307 structural constituent of muscle 3/950 42/18639 0.0714285714285714 1.40142857142857 0.362313528224005 0.889658270323882 GO:0019894 kinesin binding 3/950 42/18639 0.0714285714285714 1.40142857142857 0.362313528224005 0.889658270323882 GO:0042056 chemoattractant activity 3/950 42/18639 0.0714285714285714 1.40142857142857 0.362313528224005 0.889658270323882 GO:0016407 acetyltransferase activity 6/950 96/18639 0.0625 1.22625 0.364653830571511 0.889658270323882 GO:0019199 transmembrane receptor protein kinase activity 5/950 78/18639 0.0641025641025641 1.25769230769231 0.366180063887573 0.889658270323882 GO:0003707 nuclear steroid receptor activity 2/950 25/18639 0.08 1.5696 0.366589704684532 0.889658270323882 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/950 25/18639 0.08 1.5696 0.366589704684532 0.889658270323882 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/950 25/18639 0.08 1.5696 0.366589704684532 0.889658270323882 GO:0017025 TBP-class protein binding 2/950 25/18639 0.08 1.5696 0.366589704684532 0.889658270323882 GO:0019211 phosphatase activator activity 2/950 25/18639 0.08 1.5696 0.366589704684532 0.889658270323882 GO:0047617 fatty acyl-CoA hydrolase activity 2/950 25/18639 0.08 1.5696 0.366589704684532 0.889658270323882 GO:0004676 3-phosphoinositide-dependent protein kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0004711 ribosomal protein S6 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0035175 histone H3S10 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0035979 histone H2AXS139 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0044022 histone H3S28 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0044023 histone H4S1 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0044024 histone H2AS1 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0044025 histone H2BS14 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0072354 histone H3T3 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0072371 histone H2AS121 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0072518 Rho-dependent protein serine/threonine kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0140823 histone H2BS36 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0140855 histone H3S57 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0140995 histone H2A kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0140997 histone H4 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0140998 histone H2B kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:1990244 histone H2AT120 kinase activity 14/950 245/18639 0.0571428571428571 1.12114285714286 0.36885501667297 0.889658270323882 GO:0046906 tetrapyrrole binding 9/950 152/18639 0.0592105263157895 1.16171052631579 0.371069856263095 0.889658270323882 GO:0004677 DNA-dependent protein kinase activity 14/950 246/18639 0.0569105691056911 1.11658536585366 0.374585799282128 0.889658270323882 GO:0140857 histone H3T45 kinase activity 14/950 246/18639 0.0569105691056911 1.11658536585366 0.374585799282128 0.889658270323882 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/950 43/18639 0.0697674418604651 1.36883720930233 0.376395129503385 0.889658270323882 GO:0015370 solute:sodium symporter activity 5/950 79/18639 0.0632911392405063 1.24177215189873 0.376423087370863 0.889658270323882 GO:0016835 carbon-oxygen lyase activity 5/950 79/18639 0.0632911392405063 1.24177215189873 0.376423087370863 0.889658270323882 GO:0033293 monocarboxylic acid binding 5/950 79/18639 0.0632911392405063 1.24177215189873 0.376423087370863 0.889658270323882 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 4/950 61/18639 0.0655737704918033 1.28655737704918 0.377807814619632 0.889658270323882 GO:0019905 syntaxin binding 4/950 61/18639 0.0655737704918033 1.28655737704918 0.377807814619632 0.889658270323882 GO:0035402 histone H3T11 kinase activity 14/950 247/18639 0.0566801619433198 1.11206477732794 0.380328420370246 0.889658270323882 GO:0035403 histone H3T6 kinase activity 14/950 247/18639 0.0566801619433198 1.11206477732794 0.380328420370246 0.889658270323882 GO:0004725 protein tyrosine phosphatase activity 6/950 98/18639 0.0612244897959184 1.20122448979592 0.383054230320799 0.889658270323882 GO:0001637 G protein-coupled chemoattractant receptor activity 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0004435 phosphatidylinositol phospholipase C activity 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0004950 chemokine receptor activity 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0005112 Notch binding 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0005160 transforming growth factor beta receptor binding 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0008198 ferrous iron binding 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0015145 monosaccharide transmembrane transporter activity 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0016289 acyl-CoA hydrolase activity 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0050750 low-density lipoprotein particle receptor binding 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0051139 metal cation:proton antiporter activity 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0070412 R-SMAD binding 2/950 26/18639 0.0769230769230769 1.50923076923077 0.385108706281566 0.889658270323882 GO:0005506 iron ion binding 9/950 154/18639 0.0584415584415584 1.14662337662338 0.385693355211021 0.889658270323882 GO:0004679 AMP-activated protein kinase activity 14/950 248/18639 0.0564516129032258 1.10758064516129 0.386081588053568 0.889658270323882 GO:0016757 glycosyltransferase activity 15/950 267/18639 0.0561797752808989 1.10224719101124 0.386685798932032 0.889658270323882 GO:0016779 nucleotidyltransferase activity 8/950 136/18639 0.0588235294117647 1.15411764705882 0.390739337790997 0.889658270323882 GO:0140789 histone phosphatase activity 8/950 136/18639 0.0588235294117647 1.15411764705882 0.390739337790997 0.889658270323882 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/950 27/18639 0.0740740740740741 1.45333333333333 0.403387526984304 0.889658270323882 GO:0001094 TFIID-class transcription factor complex binding 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0004955 prostaglandin receptor activity 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0005522 profilin binding 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0008190 eukaryotic initiation factor 4E binding 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0008401 retinoic acid 4-hydroxylase activity 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0008519 ammonium channel activity 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0016427 tRNA (cytidine) methyltransferase activity 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0031996 thioesterase binding 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0032052 bile acid binding 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0032356 oxidized DNA binding 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0043295 glutathione binding 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0070097 delta-catenin binding 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0141109 transporter activator activity 1/950 10/18639 0.1 1.962 0.407415339581925 0.889658270323882 GO:0004180 carboxypeptidase activity 3/950 46/18639 0.0652173913043478 1.2795652173913 0.41818907350303 0.889658270323882 GO:0046875 ephrin receptor binding 2/950 28/18639 0.0714285714285714 1.40142857142857 0.421402540871366 0.889658270323882 GO:0051019 mitogen-activated protein kinase binding 2/950 28/18639 0.0714285714285714 1.40142857142857 0.421402540871366 0.889658270323882 GO:0051119 sugar transmembrane transporter activity 2/950 28/18639 0.0714285714285714 1.40142857142857 0.421402540871366 0.889658270323882 GO:0051393 alpha-actinin binding 2/950 28/18639 0.0714285714285714 1.40142857142857 0.421402540871366 0.889658270323882 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/950 28/18639 0.0714285714285714 1.40142857142857 0.421402540871366 0.889658270323882 GO:0051117 ATPase binding 5/950 84/18639 0.0595238095238095 1.16785714285714 0.42745834118534 0.889658270323882 GO:0043495 protein-membrane adaptor activity 3/950 47/18639 0.0638297872340425 1.25234042553191 0.431922660536799 0.889658270323882 GO:0008235 metalloexopeptidase activity 4/950 66/18639 0.0606060606060606 1.18909090909091 0.435933298786176 0.889658270323882 GO:0000099 sulfur amino acid transmembrane transporter activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0003953 NAD+ nucleosidase activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0004954 prostanoid receptor activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0005114 type II transforming growth factor beta receptor binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0005536 D-glucose binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0008199 ferric iron binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0010854 adenylate cyclase regulator activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0015173 aromatic amino acid transmembrane transporter activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0019206 nucleoside kinase activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0019215 intermediate filament binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0032050 clathrin heavy chain binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0034056 estrogen response element binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0034713 type I transforming growth factor beta receptor binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0048407 platelet-derived growth factor binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0050786 RAGE receptor binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0050998 nitric-oxide synthase binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0070697 activin receptor binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0140031 phosphorylation-dependent protein binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0140537 transcription regulator activator activity 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:1900750 oligopeptide binding 1/950 11/18639 0.0909090909090909 1.78363636363636 0.437634644289488 0.889658270323882 GO:0004181 metallocarboxypeptidase activity 2/950 29/18639 0.0689655172413793 1.35310344827586 0.439133148871096 0.889658270323882 GO:0004629 phospholipase C activity 2/950 29/18639 0.0689655172413793 1.35310344827586 0.439133148871096 0.889658270323882 GO:0005416 amino acid:monoatomic cation symporter activity 2/950 29/18639 0.0689655172413793 1.35310344827586 0.439133148871096 0.889658270323882 GO:0051020 GTPase binding 17/950 315/18639 0.053968253968254 1.05885714285714 0.439622444399427 0.889658270323882 GO:0030695 GTPase regulator activity 26/950 489/18639 0.0531697341513292 1.04319018404908 0.440676297883598 0.889658270323882 GO:0141003 histone H2AX kinase activity 19/950 354/18639 0.0536723163841808 1.05305084745763 0.441836883317022 0.889658270323882 GO:0016829 lyase activity 11/950 200/18639 0.055 1.0791 0.441887412449947 0.889658270323882 GO:0060589 nucleoside-triphosphatase regulator activity 26/950 490/18639 0.0530612244897959 1.0410612244898 0.444892126348441 0.889658270323882 GO:0050840 extracellular matrix binding 4/950 67/18639 0.0597014925373134 1.17134328358209 0.447393665979432 0.889658270323882 GO:0001968 fibronectin binding 2/950 30/18639 0.0666666666666667 1.308 0.456561532144769 0.889658270323882 GO:0016769 transferase activity, transferring nitrogenous groups 2/950 30/18639 0.0666666666666667 1.308 0.456561532144769 0.889658270323882 GO:0031210 phosphatidylcholine binding 2/950 30/18639 0.0666666666666667 1.308 0.456561532144769 0.889658270323882 GO:0140996 histone H3 kinase activity 19/950 357/18639 0.0532212885154062 1.04420168067227 0.456663488539757 0.889658270323882 GO:0030145 manganese ion binding 4/950 68/18639 0.0588235294117647 1.15411764705882 0.458780118833475 0.889658270323882 GO:0005004 GPI-linked ephrin receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0005008 hepatocyte growth factor receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0005009 insulin receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0005011 macrophage colony-stimulating factor receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0005020 stem cell factor receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0008288 boss receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0036332 placental growth factor receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0038062 protein tyrosine kinase collagen receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0060175 brain-derived neurotrophic factor receptor activity 3/950 49/18639 0.0612244897959184 1.20122448979592 0.459017642054922 0.889658270323882 GO:0019888 protein phosphatase regulator activity 6/950 107/18639 0.0560747663551402 1.10018691588785 0.46535126505009 0.889658270323882 GO:0015103 inorganic anion transmembrane transporter activity 9/950 165/18639 0.0545454545454545 1.07018181818182 0.466154784717164 0.889658270323882 GO:0003720 telomerase activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0004875 complement receptor activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0005049 nuclear export signal receptor activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0005095 GTPase inhibitor activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0005247 voltage-gated chloride channel activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0005436 sodium:phosphate symporter activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0008504 monoamine transmembrane transporter activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0015166 polyol transmembrane transporter activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0015269 calcium-activated potassium channel activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0016273 arginine N-methyltransferase activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0016274 protein-arginine N-methyltransferase activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0035497 cAMP response element binding 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0042301 phosphate ion binding 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0140900 chloride:bicarbonate antiporter activity 1/950 12/18639 0.0833333333333333 1.635 0.466314432131714 0.889658270323882 GO:0015293 symporter activity 8/950 146/18639 0.0547945205479452 1.07506849315068 0.468678291790109 0.889658270323882 GO:0035173 histone kinase activity 19/950 360/18639 0.0527777777777778 1.0355 0.471466514673107 0.889658270323882 GO:0005006 epidermal growth factor receptor activity 3/950 50/18639 0.06 1.1772 0.472356966955762 0.889658270323882 GO:0005007 fibroblast growth factor receptor activity 3/950 50/18639 0.06 1.1772 0.472356966955762 0.889658270323882 GO:0005017 platelet-derived growth factor receptor activity 3/950 50/18639 0.06 1.1772 0.472356966955762 0.889658270323882 GO:0005019 platelet-derived growth factor beta-receptor activity 3/950 50/18639 0.06 1.1772 0.472356966955762 0.889658270323882 GO:0005184 neuropeptide hormone activity 2/950 31/18639 0.0645161290322581 1.2658064516129 0.47367242270364 0.889658270323882 GO:0005452 solute:inorganic anion antiporter activity 2/950 31/18639 0.0645161290322581 1.2658064516129 0.47367242270364 0.889658270323882 GO:0047499 calcium-independent phospholipase A2 activity 2/950 31/18639 0.0645161290322581 1.2658064516129 0.47367242270364 0.889658270323882 GO:0070325 lipoprotein particle receptor binding 2/950 31/18639 0.0645161290322581 1.2658064516129 0.47367242270364 0.889658270323882 GO:0005496 steroid binding 6/950 108/18639 0.0555555555555556 1.09 0.474352724457121 0.889658270323882 GO:0031490 chromatin DNA binding 7/950 128/18639 0.0546875 1.07296875 0.479656250264419 0.889658270323882 GO:0016782 transferase activity, transferring sulphur-containing groups 4/950 70/18639 0.0571428571428571 1.12114285714286 0.481302278818128 0.889658270323882 GO:0031406 carboxylic acid binding 10/950 187/18639 0.053475935828877 1.04919786096257 0.484332610552792 0.889658270323882 GO:0005010 insulin-like growth factor receptor activity 3/950 51/18639 0.0588235294117647 1.15411764705882 0.485544222069709 0.889658270323882 GO:0005021 vascular endothelial growth factor receptor activity 3/950 51/18639 0.0588235294117647 1.15411764705882 0.485544222069709 0.889658270323882 GO:0005030 neurotrophin receptor activity 3/950 51/18639 0.0588235294117647 1.15411764705882 0.485544222069709 0.889658270323882 GO:0030515 snoRNA binding 2/950 32/18639 0.0625 1.22625 0.490452890146602 0.889658270323882 GO:0031369 translation initiation factor binding 2/950 32/18639 0.0625 1.22625 0.490452890146602 0.889658270323882 GO:0047498 calcium-dependent phospholipase A2 activity 2/950 32/18639 0.0625 1.22625 0.490452890146602 0.889658270323882 GO:0051059 NF-kappaB binding 2/950 32/18639 0.0625 1.22625 0.490452890146602 0.889658270323882 GO:0071813 lipoprotein particle binding 2/950 32/18639 0.0625 1.22625 0.490452890146602 0.889658270323882 GO:0071814 protein-lipid complex binding 2/950 32/18639 0.0625 1.22625 0.490452890146602 0.889658270323882 GO:0140142 nucleocytoplasmic carrier activity 2/950 32/18639 0.0625 1.22625 0.490452890146602 0.889658270323882 GO:0160041 neuropeptide activity 2/950 32/18639 0.0625 1.22625 0.490452890146602 0.889658270323882 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0003964 RNA-directed DNA polymerase activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0004465 lipoprotein lipase activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0005172 vascular endothelial growth factor receptor binding 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0008035 high-density lipoprotein particle binding 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0008253 5'-nucleotidase activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0017154 semaphorin receptor activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0031994 insulin-like growth factor I binding 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0032396 inhibitory MHC class I receptor activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0035673 oligopeptide transmembrane transporter activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0043560 insulin receptor substrate binding 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0045159 myosin II binding 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0046974 histone H3K9 methyltransferase activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0051011 microtubule minus-end binding 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0071837 HMG box domain binding 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/950 13/18639 0.0769230769230769 1.50923076923077 0.493533055070183 0.889658270323882 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 7/950 130/18639 0.0538461538461538 1.05646153846154 0.496070209932713 0.8925540925431 GO:0043177 organic acid binding 10/950 189/18639 0.0529100529100529 1.03809523809524 0.497930008309012 0.893699200201078 GO:0005080 protein kinase C binding 3/950 52/18639 0.0576923076923077 1.13192307692308 0.498570461008943 0.893699200201078 GO:0019956 chemokine binding 2/950 33/18639 0.0606060606060606 1.18909090909091 0.506892143473755 0.896187968702124 GO:0005085 guanyl-nucleotide exchange factor activity 12/950 230/18639 0.0521739130434783 1.02365217391304 0.509062996067757 0.896187968702124 GO:0004864 protein phosphatase inhibitor activity 3/950 53/18639 0.0566037735849057 1.11056603773585 0.511427520732601 0.896187968702124 GO:0005003 ephrin receptor activity 3/950 53/18639 0.0566037735849057 1.11056603773585 0.511427520732601 0.896187968702124 GO:0005005 transmembrane-ephrin receptor activity 3/950 53/18639 0.0566037735849057 1.11056603773585 0.511427520732601 0.896187968702124 GO:0038064 collagen receptor activity 3/950 53/18639 0.0566037735849057 1.11056603773585 0.511427520732601 0.896187968702124 GO:0051213 dioxygenase activity 5/950 93/18639 0.0537634408602151 1.05483870967742 0.516664267434772 0.896187968702124 GO:0005096 GTPase activator activity 14/950 271/18639 0.0516605166051661 1.01357933579336 0.51844661760961 0.896187968702124 GO:0005313 L-glutamate transmembrane transporter activity 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:0008174 mRNA methyltransferase activity 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:0008191 metalloendopeptidase inhibitor activity 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:0030983 mismatched DNA binding 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:0031404 chloride ion binding 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:0043176 amine binding 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:0061783 peptidoglycan muralytic activity 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:0071933 Arp2/3 complex binding 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:1901612 cardiolipin binding 1/950 14/18639 0.0714285714285714 1.40142857142857 0.51936488142492 0.896187968702124 GO:0008376 acetylgalactosaminyltransferase activity 2/950 34/18639 0.0588235294117647 1.15411764705882 0.522981346995601 0.896187968702124 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/950 34/18639 0.0588235294117647 1.15411764705882 0.522981346995601 0.896187968702124 GO:0016831 carboxy-lyase activity 2/950 34/18639 0.0588235294117647 1.15411764705882 0.522981346995601 0.896187968702124 GO:0030332 cyclin binding 2/950 34/18639 0.0588235294117647 1.15411764705882 0.522981346995601 0.896187968702124 GO:0050661 NADP binding 3/950 54/18639 0.0555555555555556 1.09 0.524107991646482 0.896187968702124 GO:0140463 chromatin-protein adaptor activity 3/950 54/18639 0.0555555555555556 1.09 0.524107991646482 0.896187968702124 GO:0003684 damaged DNA binding 4/950 74/18639 0.0540540540540541 1.06054054054054 0.52516238470193 0.896187968702124 GO:0016410 N-acyltransferase activity 5/950 94/18639 0.0531914893617021 1.0436170212766 0.52623534680169 0.896187968702124 GO:0001221 transcription coregulator binding 6/950 115/18639 0.0521739130434783 1.02365217391304 0.535933143349433 0.896187968702124 GO:0004674 protein serine/threonine kinase activity 22/950 433/18639 0.0508083140877598 0.996859122401848 0.537634775650199 0.896187968702124 GO:0004623 phospholipase A2 activity 2/950 35/18639 0.0571428571428571 1.12114285714286 0.538713449418212 0.896187968702124 GO:0034061 DNA polymerase activity 2/950 35/18639 0.0571428571428571 1.12114285714286 0.538713449418212 0.896187968702124 GO:0043015 gamma-tubulin binding 2/950 35/18639 0.0571428571428571 1.12114285714286 0.538713449418212 0.896187968702124 GO:0061631 ubiquitin conjugating enzyme activity 2/950 35/18639 0.0571428571428571 1.12114285714286 0.538713449418212 0.896187968702124 GO:0140566 histone reader activity 2/950 35/18639 0.0571428571428571 1.12114285714286 0.538713449418212 0.896187968702124 GO:1901681 sulfur compound binding 14/950 275/18639 0.0509090909090909 0.998836363636364 0.54088596269749 0.896187968702124 GO:0004953 icosanoid receptor activity 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0005523 tropomyosin binding 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0008252 nucleotidase activity 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0015250 water channel activity 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0042809 nuclear vitamin D receptor binding 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0045504 dynein heavy chain binding 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0048531 beta-1,3-galactosyltransferase activity 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0050700 CARD domain binding 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0051371 muscle alpha-actinin binding 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0140161 monocarboxylate:sodium symporter activity 1/950 15/18639 0.0666666666666667 1.308 0.5438804982113 0.896187968702124 GO:0003713 transcription coactivator activity 13/950 256/18639 0.05078125 0.996328125 0.545942849523468 0.898043212166391 GO:0019212 phosphatase inhibitor activity 3/950 56/18639 0.0535714285714286 1.05107142857143 0.548913114291279 0.90138300788585 GO:0019208 phosphatase regulator activity 6/950 117/18639 0.0512820512820513 1.00615384615385 0.552967910419705 0.906489275371789 GO:0003724 RNA helicase activity 4/950 77/18639 0.051948051948052 1.01922077922078 0.556847057933061 0.90795412597672 GO:0003688 DNA replication origin binding 1/950 16/18639 0.0625 1.22625 0.567146903210186 0.90795412597672 GO:0005149 interleukin-1 receptor binding 1/950 16/18639 0.0625 1.22625 0.567146903210186 0.90795412597672 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/950 16/18639 0.0625 1.22625 0.567146903210186 0.90795412597672 GO:0005521 lamin binding 1/950 16/18639 0.0625 1.22625 0.567146903210186 0.90795412597672 GO:0008142 oxysterol binding 1/950 16/18639 0.0625 1.22625 0.567146903210186 0.90795412597672 GO:0015378 sodium:chloride symporter activity 1/950 16/18639 0.0625 1.22625 0.567146903210186 0.90795412597672 GO:0016722 oxidoreductase activity, acting on metal ions 1/950 16/18639 0.0625 1.22625 0.567146903210186 0.90795412597672 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/950 16/18639 0.0625 1.22625 0.567146903210186 0.90795412597672 GO:0030280 structural constituent of skin epidermis 2/950 37/18639 0.0540540540540541 1.06054054054054 0.569086127662773 0.90795412597672 GO:0042805 actinin binding 2/950 37/18639 0.0540540540540541 1.06054054054054 0.569086127662773 0.90795412597672 GO:0106310 protein serine kinase activity 18/950 361/18639 0.0498614958448753 0.978282548476454 0.572882572396272 0.90795412597672 GO:0008186 ATP-dependent activity, acting on RNA 4/950 79/18639 0.0506329113924051 0.993417721518987 0.577325664312301 0.90795412597672 GO:0005501 retinoid binding 2/950 38/18639 0.0526315789473684 1.03263157894737 0.583720152222931 0.90795412597672 GO:0019840 isoprenoid binding 2/950 38/18639 0.0526315789473684 1.03263157894737 0.583720152222931 0.90795412597672 GO:0042887 amide transmembrane transporter activity 2/950 38/18639 0.0526315789473684 1.03263157894737 0.583720152222931 0.90795412597672 GO:0015459 potassium channel regulator activity 3/950 59/18639 0.0508474576271186 0.997627118644068 0.584651101188682 0.90795412597672 GO:0004549 tRNA-specific ribonuclease activity 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0005092 GDP-dissociation inhibitor activity 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0008429 phosphatidylethanolamine binding 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0016805 dipeptidase activity 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0030169 low-density lipoprotein particle binding 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0031489 myosin V binding 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0036041 long-chain fatty acid binding 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0045125 bioactive lipid receptor activity 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0048038 quinone binding 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0070402 NADPH binding 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0070492 oligosaccharide binding 1/950 17/18639 0.0588235294117647 1.15411764705882 0.589227687291716 0.90795412597672 GO:0001098 basal transcription machinery binding 3/950 60/18639 0.05 0.981 0.596154812849625 0.90795412597672 GO:0001099 basal RNA polymerase II transcription machinery binding 3/950 60/18639 0.05 0.981 0.596154812849625 0.90795412597672 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/950 60/18639 0.05 0.981 0.596154812849625 0.90795412597672 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/950 60/18639 0.05 0.981 0.596154812849625 0.90795412597672 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/950 39/18639 0.0512820512820513 1.00615384615385 0.597983710490356 0.90795412597672 GO:0008237 metallopeptidase activity 9/950 184/18639 0.0489130434782609 0.959673913043478 0.598422435738502 0.90795412597672 GO:0008238 exopeptidase activity 5/950 102/18639 0.0490196078431373 0.961764705882353 0.599495858685398 0.90795412597672 GO:0015171 amino acid transmembrane transporter activity 5/950 102/18639 0.0490196078431373 0.961764705882353 0.599495858685398 0.90795412597672 GO:0016836 hydro-lyase activity 3/950 61/18639 0.0491803278688525 0.964918032786885 0.6074486231029 0.90795412597672 GO:0005253 monoatomic anion channel activity 5/950 103/18639 0.0485436893203883 0.952427184466019 0.608195276116942 0.90795412597672 GO:0000900 mRNA regulatory element binding translation repressor activity 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0005372 water transmembrane transporter activity 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0008308 voltage-gated monoatomic anion channel activity 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0015280 ligand-gated sodium channel activity 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0015373 monoatomic anion:sodium symporter activity 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0022851 GABA-gated chloride ion channel activity 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0032393 MHC class I receptor activity 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0035615 clathrin adaptor activity 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0050811 GABA receptor binding 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0070628 proteasome binding 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:1901611 phosphatidylglycerol binding 1/950 18/18639 0.0555555555555556 1.09 0.610183207486801 0.90795412597672 GO:0015036 disulfide oxidoreductase activity 2/950 40/18639 0.05 0.981 0.611876513109098 0.90795412597672 GO:0050997 quaternary ammonium group binding 2/950 40/18639 0.05 0.981 0.611876513109098 0.90795412597672 GO:0061791 GTPase motor activity 2/950 40/18639 0.05 0.981 0.611876513109098 0.90795412597672 GO:0071855 neuropeptide receptor binding 2/950 40/18639 0.05 0.981 0.611876513109098 0.90795412597672 GO:0071949 FAD binding 2/950 40/18639 0.05 0.981 0.611876513109098 0.90795412597672 GO:1990606 membrane scission GTPase motor activity 2/950 40/18639 0.05 0.981 0.611876513109098 0.90795412597672 GO:0005254 chloride channel activity 4/950 83/18639 0.0481927710843374 0.945542168674699 0.616611665330401 0.90795412597672 GO:0046943 carboxylic acid transmembrane transporter activity 9/950 188/18639 0.0478723404255319 0.939255319148936 0.624234760215415 0.90795412597672 GO:0001530 lipopolysaccharide binding 2/950 41/18639 0.0487804878048781 0.957073170731707 0.625399261590112 0.90795412597672 GO:0001727 lipid kinase activity 2/950 41/18639 0.0487804878048781 0.957073170731707 0.625399261590112 0.90795412597672 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/950 41/18639 0.0487804878048781 0.957073170731707 0.625399261590112 0.90795412597672 GO:0140828 metal cation:monoatomic cation antiporter activity 2/950 41/18639 0.0487804878048781 0.957073170731707 0.625399261590112 0.90795412597672 GO:0004527 exonuclease activity 4/950 84/18639 0.0476190476190476 0.934285714285714 0.626069331537655 0.90795412597672 GO:1901682 sulfur compound transmembrane transporter activity 3/950 63/18639 0.0476190476190476 0.934285714285714 0.629397160694442 0.90795412597672 GO:0003756 protein disulfide isomerase activity 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0004890 GABA-A receptor activity 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0005520 insulin-like growth factor binding 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0008301 DNA binding, bending 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0008381 mechanosensitive monoatomic ion channel activity 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0015245 fatty acid transmembrane transporter activity 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0030506 ankyrin binding 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0031420 alkali metal ion binding 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0042834 peptidoglycan binding 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0043395 heparan sulfate proteoglycan binding 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:1990380 K48-linked deubiquitinase activity 1/950 19/18639 0.0526315789473684 1.03263157894737 0.630070751275402 0.90795412597672 GO:0005342 organic acid transmembrane transporter activity 9/950 189/18639 0.0476190476190476 0.934285714285714 0.630549997810736 0.90795412597672 GO:0000149 SNARE binding 5/950 106/18639 0.0471698113207547 0.925471698113208 0.633626344559279 0.911015988654196 GO:0004520 DNA endonuclease activity 2/950 42/18639 0.0476190476190476 0.934285714285714 0.638553548258417 0.913989332507197 GO:0031492 nucleosomal DNA binding 2/950 42/18639 0.0476190476190476 0.934285714285714 0.638553548258417 0.913989332507197 GO:0048487 beta-tubulin binding 2/950 42/18639 0.0476190476190476 0.934285714285714 0.638553548258417 0.913989332507197 GO:0004536 DNA nuclease activity 3/950 64/18639 0.046875 0.9196875 0.640048388106083 0.914763642613611 GO:0000339 RNA cap binding 1/950 20/18639 0.05 0.981 0.648944692536861 0.920618284234984 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/950 20/18639 0.05 0.981 0.648944692536861 0.920618284234984 GO:0010851 cyclase regulator activity 1/950 20/18639 0.05 0.981 0.648944692536861 0.920618284234984 GO:0016408 C-acyltransferase activity 1/950 20/18639 0.05 0.981 0.648944692536861 0.920618284234984 GO:0061608 nuclear import signal receptor activity 1/950 20/18639 0.05 0.981 0.648944692536861 0.920618284234984 GO:0008200 ion channel inhibitor activity 2/950 43/18639 0.0465116279069767 0.912558139534884 0.651341763807443 0.921293143792534 GO:0008375 acetylglucosaminyltransferase activity 2/950 43/18639 0.0465116279069767 0.912558139534884 0.651341763807443 0.921293143792534 GO:0004620 phospholipase activity 5/950 109/18639 0.0458715596330275 0.9 0.658021554163361 0.925492789235962 GO:0001223 transcription coactivator binding 2/950 44/18639 0.0454545454545455 0.891818181818182 0.663767011946311 0.925492789235962 GO:0016248 channel inhibitor activity 2/950 44/18639 0.0454545454545455 0.891818181818182 0.663767011946311 0.925492789235962 GO:0016790 thiolester hydrolase activity 2/950 44/18639 0.0454545454545455 0.891818181818182 0.663767011946311 0.925492789235962 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/950 44/18639 0.0454545454545455 0.891818181818182 0.663767011946311 0.925492789235962 GO:0030547 signaling receptor inhibitor activity 2/950 44/18639 0.0454545454545455 0.891818181818182 0.663767011946311 0.925492789235962 GO:0043014 alpha-tubulin binding 2/950 44/18639 0.0454545454545455 0.891818181818182 0.663767011946311 0.925492789235962 GO:0004222 metalloendopeptidase activity 5/950 110/18639 0.0454545454545455 0.891818181818182 0.66591685064611 0.925492789235962 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/950 21/18639 0.0476190476190476 0.934285714285714 0.666856639585036 0.925492789235962 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/950 21/18639 0.0476190476190476 0.934285714285714 0.666856639585036 0.925492789235962 GO:0005123 death receptor binding 1/950 21/18639 0.0476190476190476 0.934285714285714 0.666856639585036 0.925492789235962 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/950 21/18639 0.0476190476190476 0.934285714285714 0.666856639585036 0.925492789235962 GO:0015125 bile acid transmembrane transporter activity 1/950 21/18639 0.0476190476190476 0.934285714285714 0.666856639585036 0.925492789235962 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/950 67/18639 0.0447761194029851 0.878507462686567 0.670697997980785 0.928669125776387 GO:0003727 single-stranded RNA binding 4/950 89/18639 0.0449438202247191 0.881797752808989 0.671082068991696 0.928669125776387 GO:0004721 phosphoprotein phosphatase activity 8/950 175/18639 0.0457142857142857 0.896914285714286 0.673664301793251 0.930899229711423 GO:0051539 4 iron, 4 sulfur cluster binding 2/950 45/18639 0.0444444444444444 0.872 0.675833030658381 0.931212466093947 GO:0141110 transporter inhibitor activity 2/950 45/18639 0.0444444444444444 0.872 0.675833030658381 0.931212466093947 GO:0016758 hexosyltransferase activity 9/950 197/18639 0.0456852791878173 0.896345177664975 0.678939807702691 0.932884064134137 GO:0032934 sterol binding 3/950 68/18639 0.0441176470588235 0.865588235294118 0.680478823172199 0.932884064134137 GO:1990841 promoter-specific chromatin binding 3/950 68/18639 0.0441176470588235 0.865588235294118 0.680478823172199 0.932884064134137 GO:0015377 chloride:monoatomic cation symporter activity 1/950 22/18639 0.0454545454545455 0.891818181818182 0.683855575689571 0.932884064134137 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/950 22/18639 0.0454545454545455 0.891818181818182 0.683855575689571 0.932884064134137 GO:0034062 5'-3' RNA polymerase activity 1/950 22/18639 0.0454545454545455 0.891818181818182 0.683855575689571 0.932884064134137 GO:0097747 RNA polymerase activity 1/950 22/18639 0.0454545454545455 0.891818181818182 0.683855575689571 0.932884064134137 GO:0030276 clathrin binding 2/950 46/18639 0.0434782608695652 0.853043478260869 0.687544119619988 0.936246143337869 GO:0008080 N-acetyltransferase activity 3/950 69/18639 0.0434782608695652 0.853043478260869 0.690042164758704 0.936246143337869 GO:0015297 antiporter activity 6/950 135/18639 0.0444444444444444 0.872 0.691203879248726 0.936246143337869 GO:0005504 fatty acid binding 2/950 47/18639 0.0425531914893617 0.834893617021277 0.698905073357018 0.936246143337869 GO:0140359 ABC-type transporter activity 2/950 47/18639 0.0425531914893617 0.834893617021277 0.698905073357018 0.936246143337869 GO:0140938 histone H3 methyltransferase activity 2/950 47/18639 0.0425531914893617 0.834893617021277 0.698905073357018 0.936246143337869 GO:0003887 DNA-directed DNA polymerase activity 1/950 23/18639 0.0434782608695652 0.853043478260869 0.699987992464288 0.936246143337869 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/950 23/18639 0.0434782608695652 0.853043478260869 0.699987992464288 0.936246143337869 GO:0005158 insulin receptor binding 1/950 23/18639 0.0434782608695652 0.853043478260869 0.699987992464288 0.936246143337869 GO:0016849 phosphorus-oxygen lyase activity 1/950 23/18639 0.0434782608695652 0.853043478260869 0.699987992464288 0.936246143337869 GO:0016917 GABA receptor activity 1/950 23/18639 0.0434782608695652 0.853043478260869 0.699987992464288 0.936246143337869 GO:0042171 lysophosphatidic acid acyltransferase activity 1/950 23/18639 0.0434782608695652 0.853043478260869 0.699987992464288 0.936246143337869 GO:0071617 lysophospholipid acyltransferase activity 1/950 23/18639 0.0434782608695652 0.853043478260869 0.699987992464288 0.936246143337869 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/950 23/18639 0.0434782608695652 0.853043478260869 0.699987992464288 0.936246143337869 GO:0035401 histone H3Y41 kinase activity 5/950 115/18639 0.0434782608695652 0.853043478260869 0.703580437958563 0.938433435329989 GO:0140801 histone H2AXY142 kinase activity 5/950 115/18639 0.0434782608695652 0.853043478260869 0.703580437958563 0.938433435329989 GO:0015291 secondary active transmembrane transporter activity 13/950 287/18639 0.0452961672473868 0.888710801393728 0.708369881841635 0.939686024395296 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/950 181/18639 0.0441988950276243 0.867182320441989 0.709503316049739 0.939686024395296 GO:0042562 hormone binding 4/950 94/18639 0.0425531914893617 0.834893617021277 0.71221601046893 0.939686024395296 GO:0004622 lysophospholipase activity 1/950 24/18639 0.0416666666666667 0.8175 0.715298016484428 0.939686024395296 GO:0004806 triacylglycerol lipase activity 1/950 24/18639 0.0416666666666667 0.8175 0.715298016484428 0.939686024395296 GO:0005315 phosphate transmembrane transporter activity 1/950 24/18639 0.0416666666666667 0.8175 0.715298016484428 0.939686024395296 GO:0005540 hyaluronic acid binding 1/950 24/18639 0.0416666666666667 0.8175 0.715298016484428 0.939686024395296 GO:0050431 transforming growth factor beta binding 1/950 24/18639 0.0416666666666667 0.8175 0.715298016484428 0.939686024395296 GO:0060229 lipase activator activity 1/950 24/18639 0.0416666666666667 0.8175 0.715298016484428 0.939686024395296 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/950 24/18639 0.0416666666666667 0.8175 0.715298016484428 0.939686024395296 GO:0070840 dynein complex binding 1/950 24/18639 0.0416666666666667 0.8175 0.715298016484428 0.939686024395296 GO:0070851 growth factor receptor binding 6/950 139/18639 0.0431654676258993 0.846906474820144 0.717732395148245 0.93989953386092 GO:0001222 transcription corepressor binding 2/950 49/18639 0.0408163265306122 0.800816326530612 0.720597863475412 0.93989953386092 GO:0004713 protein tyrosine kinase activity 6/950 140/18639 0.0428571428571429 0.840857142857143 0.724112075501261 0.93989953386092 GO:0004521 RNA endonuclease activity 3/950 73/18639 0.0410958904109589 0.806301369863014 0.726138997041293 0.93989953386092 GO:0140104 molecular carrier activity 11/950 249/18639 0.0441767068273092 0.866746987951807 0.729000354034528 0.93989953386092 GO:0000030 mannosyltransferase activity 1/950 25/18639 0.04 0.7848 0.72982752947609 0.93989953386092 GO:0001848 complement binding 1/950 25/18639 0.04 0.7848 0.72982752947609 0.93989953386092 GO:0008483 transaminase activity 1/950 25/18639 0.04 0.7848 0.72982752947609 0.93989953386092 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/950 25/18639 0.04 0.7848 0.72982752947609 0.93989953386092 GO:0042974 nuclear retinoic acid receptor binding 1/950 25/18639 0.04 0.7848 0.72982752947609 0.93989953386092 GO:0120020 cholesterol transfer activity 1/950 25/18639 0.04 0.7848 0.72982752947609 0.93989953386092 GO:0035064 methylated histone binding 3/950 74/18639 0.0405405405405405 0.795405405405405 0.734630966576759 0.93989953386092 GO:0048029 monosaccharide binding 3/950 74/18639 0.0405405405405405 0.795405405405405 0.734630966576759 0.93989953386092 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 10/950 229/18639 0.0436681222707424 0.856768558951965 0.735927678748105 0.93989953386092 GO:0016830 carbon-carbon lyase activity 2/950 51/18639 0.0392156862745098 0.769411764705882 0.740957438738997 0.93989953386092 GO:0016791 phosphatase activity 12/950 273/18639 0.043956043956044 0.862417582417582 0.741074078464918 0.93989953386092 GO:0008170 N-methyltransferase activity 4/950 98/18639 0.0408163265306122 0.800816326530612 0.742316141206973 0.93989953386092 GO:0042626 ATPase-coupled transmembrane transporter activity 4/950 98/18639 0.0408163265306122 0.800816326530612 0.742316141206973 0.93989953386092 GO:0019003 GDP binding 3/950 75/18639 0.04 0.7848 0.742913616445398 0.93989953386092 GO:0004529 DNA exonuclease activity 1/950 26/18639 0.0384615384615385 0.754615384615385 0.743616282403871 0.93989953386092 GO:0005227 calcium-activated cation channel activity 1/950 26/18639 0.0384615384615385 0.754615384615385 0.743616282403871 0.93989953386092 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/950 26/18639 0.0384615384615385 0.754615384615385 0.743616282403871 0.93989953386092 GO:0008143 poly(A) binding 1/950 26/18639 0.0384615384615385 0.754615384615385 0.743616282403871 0.93989953386092 GO:0019865 immunoglobulin binding 1/950 26/18639 0.0384615384615385 0.754615384615385 0.743616282403871 0.93989953386092 GO:0030507 spectrin binding 1/950 26/18639 0.0384615384615385 0.754615384615385 0.743616282403871 0.93989953386092 GO:0034237 protein kinase A regulatory subunit binding 1/950 26/18639 0.0384615384615385 0.754615384615385 0.743616282403871 0.93989953386092 GO:0043548 phosphatidylinositol 3-kinase binding 1/950 26/18639 0.0384615384615385 0.754615384615385 0.743616282403871 0.93989953386092 GO:0070006 metalloaminopeptidase activity 1/950 26/18639 0.0384615384615385 0.754615384615385 0.743616282403871 0.93989953386092 GO:0004518 nuclease activity 9/950 209/18639 0.0430622009569378 0.84488038277512 0.743882947028612 0.93989953386092 GO:0051536 iron-sulfur cluster binding 3/950 76/18639 0.0394736842105263 0.774473684210526 0.750989091887029 0.945623797171574 GO:0140034 methylation-dependent protein binding 3/950 76/18639 0.0394736842105263 0.774473684210526 0.750989091887029 0.945623797171574 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 7/950 167/18639 0.0419161676646707 0.822395209580838 0.753237150427624 0.945623797171574 GO:0016874 ligase activity 7/950 167/18639 0.0419161676646707 0.822395209580838 0.753237150427624 0.945623797171574 GO:0005201 extracellular matrix structural constituent 7/950 168/18639 0.0416666666666667 0.8175 0.75865528432332 0.945623797171574 GO:0051540 metal cluster binding 3/950 77/18639 0.038961038961039 0.764415584415584 0.758859714885163 0.945623797171574 GO:0008146 sulfotransferase activity 2/950 53/18639 0.0377358490566038 0.740377358490566 0.760034305970379 0.945623797171574 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/950 53/18639 0.0377358490566038 0.740377358490566 0.760034305970379 0.945623797171574 GO:0034212 protein N-acetyltransferase activity 2/950 53/18639 0.0377358490566038 0.740377358490566 0.760034305970379 0.945623797171574 GO:0051018 protein kinase A binding 2/950 53/18639 0.0377358490566038 0.740377358490566 0.760034305970379 0.945623797171574 GO:0005216 monoatomic ion channel activity 20/950 448/18639 0.0446428571428571 0.875892857142857 0.761206153785658 0.945623797171574 GO:0005267 potassium channel activity 5/950 124/18639 0.0403225806451613 0.791129032258064 0.763670926640079 0.945623797171574 GO:0003925 G protein activity 2/950 54/18639 0.037037037037037 0.726666666666667 0.769108394982837 0.945623797171574 GO:0015485 cholesterol binding 2/950 54/18639 0.037037037037037 0.726666666666667 0.769108394982837 0.945623797171574 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/950 54/18639 0.037037037037037 0.726666666666667 0.769108394982837 0.945623797171574 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/950 54/18639 0.037037037037037 0.726666666666667 0.769108394982837 0.945623797171574 GO:0051287 NAD binding 2/950 54/18639 0.037037037037037 0.726666666666667 0.769108394982837 0.945623797171574 GO:0046625 sphingolipid binding 1/950 28/18639 0.0357142857142857 0.700714285714286 0.769120502391895 0.945623797171574 GO:0046966 nuclear thyroid hormone receptor binding 1/950 28/18639 0.0357142857142857 0.700714285714286 0.769120502391895 0.945623797171574 GO:0050698 proteoglycan sulfotransferase activity 1/950 28/18639 0.0357142857142857 0.700714285714286 0.769120502391895 0.945623797171574 GO:0051537 2 iron, 2 sulfur cluster binding 1/950 28/18639 0.0357142857142857 0.700714285714286 0.769120502391895 0.945623797171574 GO:0008374 O-acyltransferase activity 2/950 55/18639 0.0363636363636364 0.713454545454545 0.777882100930813 0.948541339222844 GO:0051861 glycolipid binding 1/950 29/18639 0.0344827586206897 0.676551724137931 0.780905765017638 0.948541339222844 GO:0004519 endonuclease activity 5/950 127/18639 0.0393700787401575 0.77244094488189 0.781522060553895 0.948541339222844 GO:0031267 small GTPase binding 12/950 283/18639 0.0424028268551237 0.831943462897527 0.782959784487625 0.948541339222844 GO:0140030 modification-dependent protein binding 7/950 173/18639 0.0404624277456647 0.793872832369942 0.784458004610758 0.948541339222844 GO:0030170 pyridoxal phosphate binding 2/950 56/18639 0.0357142857142857 0.700714285714286 0.786362433769314 0.948541339222844 GO:0170055 lipid transmembrane transporter activity 2/950 56/18639 0.0357142857142857 0.700714285714286 0.786362433769314 0.948541339222844 GO:0033192 calmodulin-dependent protein phosphatase activity 3/950 81/18639 0.037037037037037 0.726666666666667 0.788345435818949 0.948541339222844 GO:0140791 histone H2AXS140 phosphatase activity 3/950 81/18639 0.037037037037037 0.726666666666667 0.788345435818949 0.948541339222844 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/950 81/18639 0.037037037037037 0.726666666666667 0.788345435818949 0.948541339222844 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/950 81/18639 0.037037037037037 0.726666666666667 0.788345435818949 0.948541339222844 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/950 81/18639 0.037037037037037 0.726666666666667 0.788345435818949 0.948541339222844 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/950 81/18639 0.037037037037037 0.726666666666667 0.788345435818949 0.948541339222844 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/950 81/18639 0.037037037037037 0.726666666666667 0.788345435818949 0.948541339222844 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/950 81/18639 0.037037037037037 0.726666666666667 0.788345435818949 0.948541339222844 GO:0022839 monoatomic ion-gated channel activity 1/950 30/18639 0.0333333333333333 0.654 0.792090048909806 0.948541339222844 GO:0033612 receptor serine/threonine kinase binding 1/950 30/18639 0.0333333333333333 0.654 0.792090048909806 0.948541339222844 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/950 30/18639 0.0333333333333333 0.654 0.792090048909806 0.948541339222844 GO:0051721 protein phosphatase 2A binding 1/950 30/18639 0.0333333333333333 0.654 0.792090048909806 0.948541339222844 GO:0070566 adenylyltransferase activity 1/950 30/18639 0.0333333333333333 0.654 0.792090048909806 0.948541339222844 GO:0070279 vitamin B6 binding 2/950 57/18639 0.0350877192982456 0.688421052631579 0.794556469860943 0.948541339222844 GO:0004497 monooxygenase activity 4/950 106/18639 0.0377358490566038 0.740377358490566 0.795227412448006 0.948541339222844 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/950 82/18639 0.0365853658536585 0.71780487804878 0.795231737992875 0.948541339222844 GO:0033549 MAP kinase phosphatase activity 3/950 82/18639 0.0365853658536585 0.71780487804878 0.795231737992875 0.948541339222844 GO:0016298 lipase activity 5/950 130/18639 0.0384615384615385 0.754615384615385 0.798314065839204 0.949736146603489 GO:0001540 amyloid-beta binding 3/950 83/18639 0.036144578313253 0.709156626506024 0.801929990717718 0.949736146603489 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/950 83/18639 0.036144578313253 0.709156626506024 0.801929990717718 0.949736146603489 GO:0008408 3'-5' exonuclease activity 2/950 58/18639 0.0344827586206897 0.676551724137931 0.80247132702789 0.949736146603489 GO:0008327 methyl-CpG binding 1/950 31/18639 0.032258064516129 0.632903225806452 0.802703969783345 0.949736146603489 GO:0016411 acylglycerol O-acyltransferase activity 1/950 31/18639 0.032258064516129 0.632903225806452 0.802703969783345 0.949736146603489 GO:0017018 myosin phosphatase activity 3/950 84/18639 0.0357142857142857 0.700714285714286 0.808443348465127 0.949736146603489 GO:0005179 hormone activity 5/950 132/18639 0.0378787878787879 0.743181818181818 0.808933426955527 0.949736146603489 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 11/950 268/18639 0.041044776119403 0.805298507462687 0.809509368381291 0.949736146603489 GO:0031593 polyubiquitin modification-dependent protein binding 2/950 59/18639 0.0338983050847458 0.665084745762712 0.810114141969616 0.949736146603489 GO:0036002 pre-mRNA binding 2/950 59/18639 0.0338983050847458 0.665084745762712 0.810114141969616 0.949736146603489 GO:0070063 RNA polymerase binding 2/950 59/18639 0.0338983050847458 0.665084745762712 0.810114141969616 0.949736146603489 GO:0008378 galactosyltransferase activity 1/950 32/18639 0.03125 0.613125 0.812776585255498 0.949736146603489 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/950 32/18639 0.03125 0.613125 0.812776585255498 0.949736146603489 GO:0070717 poly-purine tract binding 1/950 32/18639 0.03125 0.613125 0.812776585255498 0.949736146603489 GO:0120015 sterol transfer activity 1/950 32/18639 0.03125 0.613125 0.812776585255498 0.949736146603489 GO:0008514 organic anion transmembrane transporter activity 11/950 269/18639 0.0408921933085502 0.802304832713755 0.813201510673099 0.949736146603489 GO:0033218 amide binding 10/950 247/18639 0.0404858299595142 0.794331983805668 0.814059554231562 0.949736146603489 GO:0050660 flavin adenine dinucleotide binding 3/950 86/18639 0.0348837209302326 0.684418604651163 0.820928335355289 0.95243927490902 GO:0140658 ATP-dependent chromatin remodeler activity 6/950 158/18639 0.0379746835443038 0.745063291139241 0.821853810534333 0.95243927490902 GO:0008168 methyltransferase activity 8/950 204/18639 0.0392156862745098 0.769411764705882 0.82198230109824 0.95243927490902 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/950 33/18639 0.0303030303030303 0.594545454545455 0.822335474061177 0.95243927490902 GO:0071889 14-3-3 protein binding 1/950 33/18639 0.0303030303030303 0.594545454545455 0.822335474061177 0.95243927490902 GO:0140311 protein sequestering activity 1/950 33/18639 0.0303030303030303 0.594545454545455 0.822335474061177 0.95243927490902 GO:0015026 coreceptor activity 2/950 61/18639 0.0327868852459016 0.64327868852459 0.824612166031913 0.95392408591629 GO:0008081 phosphoric diester hydrolase activity 3/950 87/18639 0.0344827586206897 0.676551724137931 0.826906581610934 0.955425797307091 GO:0015020 glucuronosyltransferase activity 1/950 34/18639 0.0294117647058824 0.577058823529412 0.831406811244982 0.955935961969973 GO:0015035 protein-disulfide reductase activity 1/950 34/18639 0.0294117647058824 0.577058823529412 0.831406811244982 0.955935961969973 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/950 34/18639 0.0294117647058824 0.577058823529412 0.831406811244982 0.955935961969973 GO:0005261 monoatomic cation channel activity 14/950 341/18639 0.0410557184750733 0.805513196480938 0.832303421771627 0.955935961969973 GO:0042578 phosphoric ester hydrolase activity 15/950 363/18639 0.0413223140495868 0.810743801652893 0.832332146240801 0.955935961969973 GO:0000287 magnesium ion binding 9/950 230/18639 0.0391304347826087 0.767739130434783 0.834534327441713 0.957318684230386 GO:0008083 growth factor activity 6/950 162/18639 0.037037037037037 0.726666666666667 0.839359251537484 0.96130645168629 GO:0016229 steroid dehydrogenase activity 1/950 35/18639 0.0285714285714286 0.560571428571428 0.840015439534005 0.96130645168629 GO:0140101 catalytic activity, acting on a tRNA 5/950 139/18639 0.0359712230215827 0.705755395683453 0.842625608408332 0.963144169801657 GO:0001217 DNA-binding transcription repressor activity 11/950 278/18639 0.039568345323741 0.776330935251799 0.844058300588273 0.963633226504945 GO:0015081 sodium ion transmembrane transporter activity 6/950 164/18639 0.0365853658536585 0.71780487804878 0.847576912098574 0.963755159555356 GO:0000993 RNA polymerase II complex binding 1/950 36/18639 0.0277777777777778 0.545 0.848184937085214 0.963755159555356 GO:0004190 aspartic-type endopeptidase activity 1/950 36/18639 0.0277777777777778 0.545 0.848184937085214 0.963755159555356 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/950 36/18639 0.0277777777777778 0.545 0.848184937085214 0.963755159555356 GO:0140597 protein carrier chaperone 7/950 188/18639 0.0372340425531915 0.730531914893617 0.849444183277237 0.964043753565527 GO:0160215 deacylase activity 2/950 65/18639 0.0307692307692308 0.603692307692308 0.850655447130356 0.964277273992921 GO:0070001 aspartic-type peptidase activity 1/950 37/18639 0.027027027027027 0.53027027027027 0.855937681791393 0.969119524011743 GO:0016741 transferase activity, transferring one-carbon groups 8/950 215/18639 0.0372093023255814 0.730046511627907 0.862296725856959 0.974036057376462 GO:0042054 histone methyltransferase activity 2/950 67/18639 0.0298507462686567 0.585671641791045 0.862311379262374 0.974036057376462 GO:0008194 UDP-glycosyltransferase activity 5/950 145/18639 0.0344827586206897 0.676551724137931 0.867465831594826 0.977955289026547 GO:0140223 general transcription initiation factor activity 2/950 68/18639 0.0294117647058824 0.577058823529412 0.867821456719652 0.977955289026547 GO:0008276 protein methyltransferase activity 3/950 95/18639 0.0315789473684211 0.619578947368421 0.868840361053825 0.977955289026547 GO:0000217 DNA secondary structure binding 1/950 39/18639 0.0256410256410256 0.503076923076923 0.870276786052637 0.978423725468322 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/950 122/18639 0.0327868852459016 0.64327868852459 0.874690845870164 0.98223480232961 GO:0004177 aminopeptidase activity 1/950 40/18639 0.025 0.4905 0.87690243407683 0.982417563410841 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/950 40/18639 0.025 0.4905 0.87690243407683 0.982417563410841 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/950 70/18639 0.0285714285714286 0.560571428571428 0.878238288739331 0.982766066395587 GO:0005249 voltage-gated potassium channel activity 3/950 98/18639 0.0306122448979592 0.600612244897959 0.882092318371655 0.984586502595535 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/950 41/18639 0.024390243902439 0.478536585365854 0.883190013388998 0.984586502595535 GO:0008227 G protein-coupled amine receptor activity 1/950 41/18639 0.024390243902439 0.478536585365854 0.883190013388998 0.984586502595535 GO:0000510 H3-H4 histone complex chaperone activity 5/950 151/18639 0.033112582781457 0.649668874172185 0.888916246075911 0.984586502595535 GO:0140584 chromatin extrusion motor activity 5/950 151/18639 0.033112582781457 0.649668874172185 0.888916246075911 0.984586502595535 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/950 151/18639 0.033112582781457 0.649668874172185 0.888916246075911 0.984586502595535 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/950 151/18639 0.033112582781457 0.649668874172185 0.888916246075911 0.984586502595535 GO:0004402 histone acetyltransferase activity 1/950 42/18639 0.0238095238095238 0.467142857142857 0.889156756440963 0.984586502595535 GO:0043175 RNA polymerase core enzyme binding 1/950 42/18639 0.0238095238095238 0.467142857142857 0.889156756440963 0.984586502595535 GO:0043130 ubiquitin binding 3/950 100/18639 0.03 0.5886 0.89025150909586 0.984586502595535 GO:0015616 DNA translocase activity 5/950 152/18639 0.0328947368421053 0.645394736842105 0.892185266689802 0.984586502595535 GO:0140674 ATP-dependent histone chaperone activity 5/950 152/18639 0.0328947368421053 0.645394736842105 0.892185266689802 0.984586502595535 GO:0042826 histone deacetylase binding 4/950 127/18639 0.031496062992126 0.617952755905512 0.893333529821069 0.984720523101615 GO:0061775 cohesin loader activity 5/950 153/18639 0.0326797385620915 0.641176470588235 0.895371020397137 0.985833304891911 GO:0003678 DNA helicase activity 2/950 74/18639 0.027027027027027 0.53027027027027 0.896832859837604 0.98631045021131 GO:0001046 core promoter sequence-specific DNA binding 1/950 44/18639 0.0227272727272727 0.445909090909091 0.900192320640659 0.98700703333514 GO:0004386 helicase activity 5/950 155/18639 0.032258064516129 0.632903225806452 0.901498977240745 0.98700703333514 GO:0004722 protein serine/threonine phosphatase activity 3/950 103/18639 0.029126213592233 0.571456310679612 0.901543494246933 0.98700703333514 GO:0046982 protein heterodimerization activity 14/950 369/18639 0.037940379403794 0.744390243902439 0.902381398620927 0.98700703333514 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/950 130/18639 0.0307692307692308 0.603692307692308 0.90331229224045 0.98700703333514 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/950 45/18639 0.0222222222222222 0.436 0.905291395412983 0.98700703333514 GO:0042605 peptide antigen binding 1/950 45/18639 0.0222222222222222 0.436 0.905291395412983 0.98700703333514 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/950 132/18639 0.0303030303030303 0.594545454545455 0.90949770203135 0.98700703333514 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/950 46/18639 0.0217391304347826 0.426521739130435 0.910130223763939 0.98700703333514 GO:0061733 protein-lysine-acetyltransferase activity 1/950 47/18639 0.0212765957446809 0.417446808510638 0.914722074859741 0.98700703333514 GO:0061749 forked DNA-dependent helicase activity 1/950 47/18639 0.0212765957446809 0.417446808510638 0.914722074859741 0.98700703333514 GO:0099095 ligand-gated monoatomic anion channel activity 1/950 47/18639 0.0212765957446809 0.417446808510638 0.914722074859741 0.98700703333514 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/950 47/18639 0.0212765957446809 0.417446808510638 0.914722074859741 0.98700703333514 GO:0003689 DNA clamp loader activity 5/950 160/18639 0.03125 0.613125 0.915470474046038 0.98700703333514 GO:0015079 potassium ion transmembrane transporter activity 5/950 160/18639 0.03125 0.613125 0.915470474046038 0.98700703333514 GO:0008188 neuropeptide receptor activity 1/950 48/18639 0.0208333333333333 0.40875 0.919079541989864 0.98700703333514 GO:0009378 four-way junction helicase activity 1/950 48/18639 0.0208333333333333 0.40875 0.919079541989864 0.98700703333514 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/950 48/18639 0.0208333333333333 0.40875 0.919079541989864 0.98700703333514 GO:0036121 double-stranded DNA helicase activity 1/950 48/18639 0.0208333333333333 0.40875 0.919079541989864 0.98700703333514 GO:0038187 pattern recognition receptor activity 1/950 48/18639 0.0208333333333333 0.40875 0.919079541989864 0.98700703333514 GO:0043138 3'-5' DNA helicase activity 1/950 48/18639 0.0208333333333333 0.40875 0.919079541989864 0.98700703333514 GO:0046873 metal ion transmembrane transporter activity 17/950 450/18639 0.0377777777777778 0.7412 0.923947580116248 0.991124976880853 GO:0140713 histone chaperone activity 5/950 164/18639 0.0304878048780488 0.598170731707317 0.925361260068382 0.991532344587238 GO:0140097 catalytic activity, acting on DNA 12/950 336/18639 0.0357142857142857 0.700714285714286 0.926861453920484 0.992031399899268 GO:0005272 sodium channel activity 1/950 51/18639 0.0196078431372549 0.384705882352941 0.930862144410071 0.994094428161757 GO:0016597 amino acid binding 1/950 51/18639 0.0196078431372549 0.384705882352941 0.930862144410071 0.994094428161757 GO:0005246 calcium channel regulator activity 1/950 53/18639 0.0188679245283019 0.370188679245283 0.937748761592651 0.999223402630392 GO:0017046 peptide hormone binding 1/950 53/18639 0.0188679245283019 0.370188679245283 0.937748761592651 0.999223402630392 GO:0042393 histone binding 8/950 247/18639 0.0323886639676113 0.635465587044534 0.939313436276955 0.999779784006215 GO:0140313 molecular sequestering activity 1/950 55/18639 0.0181818181818182 0.356727272727273 0.943950072975816 0.999999455723609 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/950 56/18639 0.0178571428571429 0.350357142857143 0.94681530277957 0.999999455723609 GO:0032182 ubiquitin-like protein binding 3/950 120/18639 0.025 0.4905 0.947869593709252 0.999999455723609 GO:0004540 RNA nuclease activity 3/950 121/18639 0.0247933884297521 0.486446280991736 0.949833032255607 0.999999455723609 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/950 91/18639 0.021978021978022 0.431208791208791 0.949979295485003 0.999999455723609 GO:0019842 vitamin binding 4/950 150/18639 0.0266666666666667 0.5232 0.95111144235102 0.999999455723609 GO:0008528 G protein-coupled peptide receptor activity 3/950 122/18639 0.0245901639344262 0.482459016393443 0.951727373088853 0.999999455723609 GO:0043178 alcohol binding 2/950 92/18639 0.0217391304347826 0.426521739130435 0.952105700639909 0.999999455723609 GO:0017116 single-stranded DNA helicase activity 1/950 58/18639 0.0172413793103448 0.338275862068965 0.95211426109767 0.999999455723609 GO:0070888 E-box binding 1/950 59/18639 0.0169491525423729 0.332542372881356 0.954562539013671 0.999999455723609 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/950 60/18639 0.0166666666666667 0.327 0.95688576764322 0.999999455723609 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/950 60/18639 0.0166666666666667 0.327 0.95688576764322 0.999999455723609 GO:0008094 ATP-dependent activity, acting on DNA 6/950 210/18639 0.0285714285714286 0.560571428571428 0.959878767430215 0.999999455723609 GO:0003730 mRNA 3'-UTR binding 8/950 262/18639 0.0305343511450382 0.599083969465649 0.960006846716884 0.999999455723609 GO:0140098 catalytic activity, acting on RNA 13/950 387/18639 0.0335917312661499 0.659069767441861 0.96121410685026 0.999999455723609 GO:0030594 neurotransmitter receptor activity 2/950 97/18639 0.0206185567010309 0.404536082474227 0.961504035661613 0.999999455723609 GO:0001653 peptide receptor activity 3/950 128/18639 0.0234375 0.45984375 0.961760372056815 0.999999455723609 GO:0022824 transmitter-gated monoatomic ion channel activity 1/950 63/18639 0.0158730158730159 0.311428571428571 0.963167354960038 0.999999455723609 GO:0022835 transmitter-gated channel activity 1/950 63/18639 0.0158730158730159 0.311428571428571 0.963167354960038 0.999999455723609 GO:0015276 ligand-gated monoatomic ion channel activity 5/950 186/18639 0.0268817204301075 0.52741935483871 0.963463555097484 0.999999455723609 GO:0022834 ligand-gated channel activity 5/950 188/18639 0.0265957446808511 0.521808510638298 0.965839879836663 0.999999455723609 GO:0120013 lipid transfer activity 1/950 65/18639 0.0153846153846154 0.301846153846154 0.966838453614772 0.999999455723609 GO:0099094 ligand-gated monoatomic cation channel activity 3/950 136/18639 0.0220588235294118 0.432794117647059 0.972114442851752 0.999999455723609 GO:0042277 peptide binding 7/950 249/18639 0.0281124497991968 0.551566265060241 0.972787869182409 0.999999455723609 GO:0016279 protein-lysine N-methyltransferase activity 1/950 69/18639 0.0144927536231884 0.284347826086957 0.973120364026264 0.999999455723609 GO:0098960 postsynaptic neurotransmitter receptor activity 1/950 69/18639 0.0144927536231884 0.284347826086957 0.973120364026264 0.999999455723609 GO:0016278 lysine N-methyltransferase activity 1/950 70/18639 0.0142857142857143 0.280285714285714 0.974495466566655 0.999999455723609 GO:0140299 molecular sensor activity 1/950 71/18639 0.0140845070422535 0.276338028169014 0.975800292177171 0.999999455723609 GO:0004843 cysteine-type deubiquitinase activity 2/950 108/18639 0.0185185185185185 0.363333333333333 0.976350341624093 0.999999455723609 GO:0005518 collagen binding 1/950 72/18639 0.0138888888888889 0.2725 0.977038428887193 0.999999455723609 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/950 73/18639 0.0136986301369863 0.268767123287671 0.978213281720562 0.999999455723609 GO:0005244 voltage-gated monoatomic ion channel activity 4/950 173/18639 0.023121387283237 0.45364161849711 0.978763187199862 0.999999455723609 GO:0022843 voltage-gated monoatomic cation channel activity 3/950 143/18639 0.020979020979021 0.411608391608392 0.978939046431081 0.999999455723609 GO:0022832 voltage-gated channel activity 4/950 175/18639 0.0228571428571429 0.448457142857143 0.980290805946481 0.999999455723609 GO:0005319 lipid transporter activity 4/950 178/18639 0.0224719101123595 0.440898876404494 0.982389046404841 0.999999455723609 GO:0101005 deubiquitinase activity 2/950 115/18639 0.0173913043478261 0.341217391304348 0.98272771949911 0.999999455723609 GO:0030246 carbohydrate binding 7/950 280/18639 0.025 0.4905 0.989900304149531 0.999999455723609 GO:0019783 ubiquitin-like protein peptidase activity 2/950 127/18639 0.015748031496063 0.308976377952756 0.989987630871199 0.999999455723609 GO:0004197 cysteine-type endopeptidase activity 1/950 88/18639 0.0113636363636364 0.222954545454545 0.990094107207905 0.999999455723609 GO:0005262 calcium channel activity 2/950 131/18639 0.0152671755725191 0.299541984732824 0.991665536288246 0.999999455723609 GO:0052689 carboxylic ester hydrolase activity 1/950 92/18639 0.0108695652173913 0.213260869565217 0.991972762527487 0.999999455723609 GO:0022836 gated channel activity 8/950 318/18639 0.0251572327044025 0.493584905660377 0.99276006240746 0.999999455723609 GO:0003823 antigen binding 3/950 174/18639 0.0172413793103448 0.338275862068965 0.994171425100257 0.999999455723609 GO:0140767 enzyme-substrate adaptor activity 2/950 139/18639 0.0143884892086331 0.282302158273381 0.994237869742088 0.999999455723609 GO:0004252 serine-type endopeptidase activity 3/950 176/18639 0.0170454545454545 0.334431818181818 0.994645870819427 0.999999455723609 GO:0015085 calcium ion transmembrane transporter activity 2/950 147/18639 0.0136054421768707 0.266938775510204 0.99602728574431 0.999999455723609 GO:0008234 cysteine-type peptidase activity 3/950 187/18639 0.0160427807486631 0.31475935828877 0.996656210054704 0.999999455723609 GO:0004175 endopeptidase activity 10/950 405/18639 0.0246913580246914 0.484444444444444 0.997369139931731 0.999999455723609 GO:0008236 serine-type peptidase activity 3/950 194/18639 0.0154639175257732 0.30340206185567 0.997529584371621 0.999999455723609 GO:0017171 serine hydrolase activity 3/950 198/18639 0.0151515151515152 0.297272727272727 0.997924137905596 0.999999455723609 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/950 122/18639 0.00819672131147541 0.160819672131148 0.998344365482939 0.999999455723609 GO:0061659 ubiquitin-like protein ligase activity 7/950 372/18639 0.0188172043010753 0.369193548387097 0.999619139708128 0.999999455723609 GO:0061630 ubiquitin protein ligase activity 6/950 353/18639 0.0169971671388102 0.333484419263456 0.999770663564185 0.999999455723609 GO:0045182 translation regulator activity 6/950 356/18639 0.0168539325842697 0.330674157303371 0.999796448776105 0.999999455723609 GO:0016755 aminoacyltransferase activity 9/950 496/18639 0.0181451612903226 0.356008064516129 0.99996207812529 0.999999455723609 GO:0019787 ubiquitin-like protein transferase activity 8/950 479/18639 0.0167014613778706 0.32768267223382 0.999978876574404 0.999999455723609 GO:0004842 ubiquitin-protein transferase activity 7/950 449/18639 0.0155902004454343 0.305879732739421 0.999981445487868 0.999999455723609 GO:0030371 translation repressor activity 2/950 329/18639 0.0060790273556231 0.119270516717325 0.999999455723609 0.999999455723609