category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 2/8 133/9376 17.6240601503759 TYROBP/GZMB 5.64239695210496 Cellular Processes Cell growth and death hsa04210 Apoptosis 2/8 137/9376 17.1094890510949 GZMB/TUBA1B 5.55055942584265 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 2/8 201/9376 11.6616915422886 GZMB/CCND2 4.46507025408896 Human Diseases Immune disease hsa05330 Allograft rejection 1/8 39/9376 30.0512820512821 GZMB 5.31252660023823 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/8 44/9376 26.6363636363636 GZMB 4.9808399533658 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/8 45/9376 26.0444444444444 GZMB 4.92108373779784 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/8 54/9376 21.7037037037037 GZMB 4.45859028105475 Environmental Information Processing Signal transduction hsa04340 Hedgehog signaling pathway 1/8 56/9376 20.9285714285714 CCND2 4.37088535661253 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/8 71/9376 16.5070422535211 CCND2 3.83272047289852 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/8 73/9376 16.0547945205479 MDFIC 3.77339215801589 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/8 75/9376 15.6266666666667 CCND2 3.71636502594649 Organismal Systems Digestive system hsa04971 Gastric acid secretion 1/8 76/9376 15.4210526315789 HRH2 3.68866720376151 Organismal Systems Immune system hsa04623 Cytosolic DNA-sensing pathway 1/8 83/9376 14.1204819277108 CGAS 3.50847232915284 Cellular Processes Cellular community - eukaryotes hsa04540 Gap junction 1/8 89/9376 13.1685393258427 TUBA1B 3.37056666428228 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/8 91/9376 12.8791208791209 BLK 3.32752429024203 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/8 133/9376 8.81203007518797 CCND2 2.65149273325964 Human Diseases Infectious disease: viral hsa05162 Measles 1/8 136/9376 8.61764705882353 CCND2 2.61493866259189 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 1/8 142/9376 8.25352112676056 TYROBP 2.54510267884295 NA NA hsa04518 Integrin signaling 1/8 154/9376 7.61038961038961 CCND2 2.41703004692752 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/8 155/9376 7.56129032258065 TUBA1B 2.40698444394355 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/8 157/9376 7.46496815286624 CCND2 2.38715983807449 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/8 157/9376 7.46496815286624 CCND2 2.38715983807449 Cellular Processes Cell growth and death hsa04110 Cell cycle 1/8 158/9376 7.41772151898734 CCND2 2.37737805920378 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/8 168/9376 6.97619047619048 CCND2 2.28403948425097 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/8 170/9376 6.89411764705882 TUBA1B 2.26628730610123 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/8 178/9376 6.58426966292135 CCND2 2.19804647742034 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/8 180/9376 6.51111111111111 CGAS 2.18164020719183 Cellular Processes Cell motility hsa04814 Motor proteins 1/8 194/9376 6.04123711340206 TUBA1B 2.07336869150688 NA NA hsa04082 Neuroactive ligand signaling 1/8 199/9376 5.8894472361809 HRH2 2.03724437274945 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/8 200/9376 5.86 TUBA1B 2.03016695883304 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/8 203/9376 5.77339901477833 CCND2 2.0092188872554 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/8 205/9376 5.71707317073171 CCND2 1.99548463215177 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 1/8 205/9376 5.71707317073171 CCND2 1.99548463215177 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/8 214/9376 5.47663551401869 CGAS 1.93584539334682 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/8 224/9376 5.23214285714286 CCND2 1.87341292902484 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/8 227/9376 5.16299559471366 CGAS 1.85540728208206 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/8 238/9376 4.92436974789916 CGAS 1.7920082779825 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/8 248/9376 4.7258064516129 TUBA1B 1.73766280781864 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/8 253/9376 4.63241106719368 CGAS 1.71156581605925 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/8 254/9376 4.61417322834646 HRH2 1.70642804307295 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 1/8 268/9376 4.37313432835821 TUBA1B 1.63718106512082 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/8 275/9376 4.26181818181818 TUBA1B 1.6043116218839 NA NA hsa04517 IgSF CAM signaling 1/8 299/9376 3.91973244147157 TUBA1B 1.49939021556913 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/8 308/9376 3.80519480519481 TUBA1B 1.46281639490694 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/8 323/9376 3.62848297213622 CCND2 1.40480925440901 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/8 333/9376 3.51951951951952 CCND2 1.36801471637586 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/8 362/9376 3.23756906077348 CCND2 1.26875903345703 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 1/8 368/9376 3.18478260869565 TUBA1B 1.24946800975133 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/8 370/9376 3.16756756756757 HRH2 1.2431247856989 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/8 388/9376 3.02061855670103 TUBA1B 1.18788899438705 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 1/8 480/9376 2.44166666666667 TUBA1B 0.947535040209385