ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0008569 minus-end-directed microtubule motor activity 7/450 17/18639 0.411764705882353 17.0552941176471 7.20021003191623e-08 5.06174765243711e-05 GO:0051959 dynein light intermediate chain binding 7/450 28/18639 0.25 10.355 3.48222745814909e-06 0.00122400295153941 GO:0003779 actin binding 27/450 443/18639 0.0609480812641084 2.52446952595937 1.11305436663012e-05 0.00239842885335224 GO:0141003 histone H2AX kinase activity 23/450 354/18639 0.0649717514124294 2.69112994350282 1.83074509080955e-05 0.00239842885335224 GO:0045505 dynein intermediate chain binding 7/450 36/18639 0.194444444444444 8.05388888888889 2.07761665825138e-05 0.00239842885335224 GO:0140996 histone H3 kinase activity 23/450 357/18639 0.0644257703081232 2.66851540616246 2.09277947649317e-05 0.00239842885335224 GO:0035173 histone kinase activity 23/450 360/18639 0.0638888888888889 2.64627777777778 2.38819373733509e-05 0.00239842885335224 GO:0003777 microtubule motor activity 9/450 68/18639 0.132352941176471 5.48205882352941 3.58825649115866e-05 0.00315318039160568 GO:0008013 beta-catenin binding 11/450 106/18639 0.10377358490566 4.29830188679245 5.08910972295953e-05 0.00397516015026728 GO:0030695 GTPase regulator activity 27/450 489/18639 0.0552147239263804 2.28699386503067 6.22619206333941e-05 0.00411853511689391 GO:0060589 nucleoside-triphosphatase regulator activity 27/450 490/18639 0.0551020408163265 2.28232653061224 6.44436504777141e-05 0.00411853511689391 GO:0022853 active monoatomic ion transmembrane transporter activity 11/450 118/18639 0.0932203389830508 3.86118644067797 0.000135254263480014 0.00792364560220414 GO:0035254 glutamate receptor binding 7/450 49/18639 0.142857142857143 5.91714285714286 0.000163160193853839 0.00882320125224993 GO:0005543 phospholipid binding 26/450 497/18639 0.0523138832997988 2.16684104627767 0.000200927776149746 0.00944794410506087 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/450 13/18639 0.307692307692308 12.7446153846154 0.000201591979482095 0.00944794410506087 GO:0005096 GTPase activator activity 17/450 271/18639 0.0627306273062731 2.59830258302583 0.000335943864866679 0.0143554211014663 GO:0003774 cytoskeletal motor activity 12/450 153/18639 0.0784313725490196 3.24862745098039 0.000347143895768033 0.0143554211014663 GO:0015399 primary active transmembrane transporter activity 12/450 166/18639 0.072289156626506 2.99421686746988 0.000723065492488251 0.02823972451218 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 7/450 68/18639 0.102941176470588 4.26382352941176 0.0012432751405281 0.0404991011388455 GO:0035256 G protein-coupled glutamate receptor binding 3/450 10/18639 0.3 12.426 0.00147819538742373 0.0404991011388455 GO:0035091 phosphatidylinositol binding 16/450 284/18639 0.0563380281690141 2.33352112676056 0.00155366584241545 0.0404991011388455 GO:0051015 actin filament binding 13/450 209/18639 0.062200956937799 2.57636363636364 0.00176113887152371 0.0404991011388455 GO:0015078 proton transmembrane transporter activity 12/450 185/18639 0.0648648648648649 2.6867027027027 0.00184088966938869 0.0404991011388455 GO:0035401 histone H3Y41 kinase activity 9/450 115/18639 0.0782608695652174 3.2415652173913 0.0018935124318057 0.0404991011388455 GO:0140801 histone H2AXY142 kinase activity 9/450 115/18639 0.0782608695652174 3.2415652173913 0.0018935124318057 0.0404991011388455 GO:0098632 cell-cell adhesion mediator activity 6/450 55/18639 0.109090909090909 4.51854545454545 0.00204215528928373 0.0404991011388455 GO:0004713 protein tyrosine kinase activity 10/450 140/18639 0.0714285714285714 2.95857142857143 0.00214485405739233 0.0404991011388455 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 14/450 243/18639 0.0576131687242798 2.38633744855967 0.00243541930333352 0.0404991011388455 GO:0004676 3-phosphoinositide-dependent protein kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0004711 ribosomal protein S6 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0035175 histone H3S10 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0035979 histone H2AXS139 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0044022 histone H3S28 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0044023 histone H4S1 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0044024 histone H2AS1 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0044025 histone H2BS14 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0072354 histone H3T3 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0072371 histone H2AS121 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0072518 Rho-dependent protein serine/threonine kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0140823 histone H2BS36 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0140855 histone H3S57 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0140995 histone H2A kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0140997 histone H4 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0140998 histone H2B kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:1990244 histone H2AT120 kinase activity 14/450 245/18639 0.0571428571428571 2.36685714285714 0.00262422326475679 0.0404991011388455 GO:0004677 DNA-dependent protein kinase activity 14/450 246/18639 0.0569105691056911 2.35723577235772 0.00272304892410113 0.0404991011388455 GO:0140857 histone H3T45 kinase activity 14/450 246/18639 0.0569105691056911 2.35723577235772 0.00272304892410113 0.0404991011388455 GO:0035402 histone H3T11 kinase activity 14/450 247/18639 0.0566801619433198 2.34769230769231 0.00282491512710759 0.0404991011388455 GO:0035403 histone H3T6 kinase activity 14/450 247/18639 0.0566801619433198 2.34769230769231 0.00282491512710759 0.0404991011388455 GO:0004679 AMP-activated protein kinase activity 14/450 248/18639 0.0564516129032258 2.33822580645161 0.00292989157001302 0.0404991011388455 GO:0008137 NADH dehydrogenase (ubiquinone) activity 5/450 41/18639 0.121951219512195 5.05121951219512 0.00293805712387072 0.0404991011388455 GO:0045296 cadherin binding 17/450 334/18639 0.0508982035928144 2.10820359281437 0.00326197839554855 0.04361698237361 GO:0030507 spectrin binding 4/450 26/18639 0.153846153846154 6.37230769230769 0.00328833579772593 0.04361698237361 GO:0003954 NADH dehydrogenase activity 5/450 44/18639 0.113636363636364 4.70681818181818 0.0040138313886376 0.0522541382631895 GO:0004674 protein serine/threonine kinase activity 20/450 433/18639 0.046189376443418 1.91316397228637 0.00448363157678757 0.0573089636087575 GO:0016500 protein-hormone receptor activity 6/450 67/18639 0.0895522388059701 3.70925373134328 0.00552088417886452 0.066055096190966 GO:0098918 structural constituent of synapse 4/450 30/18639 0.133333333333333 5.52266666666667 0.00558760981393528 0.066055096190966 GO:0016887 ATP hydrolysis activity 19/450 417/18639 0.0455635491606715 1.88724220623501 0.00636828727292009 0.066055096190966 GO:0005004 GPI-linked ephrin receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0005008 hepatocyte growth factor receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0005009 insulin receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0005011 macrophage colony-stimulating factor receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0005020 stem cell factor receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0008288 boss receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0036332 placental growth factor receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0038062 protein tyrosine kinase collagen receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0060175 brain-derived neurotrophic factor receptor activity 5/450 49/18639 0.102040816326531 4.2265306122449 0.00638939764009344 0.066055096190966 GO:0005006 epidermal growth factor receptor activity 5/450 50/18639 0.1 4.142 0.00696171710264794 0.0675041302812409 GO:0005007 fibroblast growth factor receptor activity 5/450 50/18639 0.1 4.142 0.00696171710264794 0.0675041302812409 GO:0005017 platelet-derived growth factor receptor activity 5/450 50/18639 0.1 4.142 0.00696171710264794 0.0675041302812409 GO:0005019 platelet-derived growth factor beta-receptor activity 5/450 50/18639 0.1 4.142 0.00696171710264794 0.0675041302812409 GO:0106310 protein serine kinase activity 17/450 361/18639 0.0470914127423823 1.95052631578947 0.00700967497941762 0.0675041302812409 GO:0005010 insulin-like growth factor receptor activity 5/450 51/18639 0.0980392156862745 4.06078431372549 0.0075689114186289 0.0700124306223173 GO:0005021 vascular endothelial growth factor receptor activity 5/450 51/18639 0.0980392156862745 4.06078431372549 0.0075689114186289 0.0700124306223173 GO:0005030 neurotrophin receptor activity 5/450 51/18639 0.0980392156862745 4.06078431372549 0.0075689114186289 0.0700124306223173 GO:0022804 active transmembrane transporter activity 20/450 457/18639 0.0437636761487965 1.81269146608315 0.00798317417263512 0.0728853434202921 GO:0005003 ephrin receptor activity 5/450 53/18639 0.0943396226415094 3.90754716981132 0.00889201699900724 0.0781385993787761 GO:0005005 transmembrane-ephrin receptor activity 5/450 53/18639 0.0943396226415094 3.90754716981132 0.00889201699900724 0.0781385993787761 GO:0038064 collagen receptor activity 5/450 53/18639 0.0943396226415094 3.90754716981132 0.00889201699900724 0.0781385993787761 GO:0098631 cell adhesion mediator activity 6/450 76/18639 0.0789473684210526 3.27 0.0100996110972319 0.0876546493994322 GO:0019199 transmembrane receptor protein kinase activity 6/450 78/18639 0.0769230769230769 3.18615384615385 0.0114013294515048 0.0977455439561937 GO:0005516 calmodulin binding 11/450 207/18639 0.0531400966183575 2.20106280193237 0.0120969279099327 0.102459521935936 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/450 58/18639 0.0862068965517241 3.57068965517241 0.0128795670176225 0.107789709683198 GO:0004714 transmembrane receptor protein tyrosine kinase activity 5/450 60/18639 0.0833333333333333 3.45166666666667 0.0147658062859401 0.122121903753128 GO:0099186 structural constituent of postsynapse 3/450 23/18639 0.130434782608696 5.40260869565217 0.0172945625979746 0.141372994260187 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/450 24/18639 0.125 5.1775 0.0194183823549407 0.156909457419808 GO:0000030 mannosyltransferase activity 3/450 25/18639 0.12 4.9704 0.0216796413012193 0.164555600150978 GO:0004709 MAP kinase kinase kinase activity 3/450 25/18639 0.12 4.9704 0.0216796413012193 0.164555600150978 GO:0015662 P-type ion transporter activity 3/450 25/18639 0.12 4.9704 0.0216796413012193 0.164555600150978 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/450 25/18639 0.12 4.9704 0.0216796413012193 0.164555600150978 GO:0140358 P-type transmembrane transporter activity 3/450 25/18639 0.12 4.9704 0.0216796413012193 0.164555600150978 GO:0140793 histone H2AXY142 phosphatase activity 6/450 90/18639 0.0666666666666667 2.76133333333333 0.0217690907738846 0.164555600150978 GO:0009055 electron transfer activity 7/450 116/18639 0.0603448275862069 2.49948275862069 0.022470654712875 0.168051811310118 GO:0004715 non-membrane spanning protein tyrosine kinase activity 4/450 45/18639 0.0888888888888889 3.68177777777778 0.0229141542882241 0.169564741732859 GO:0004435 phosphatidylinositol phospholipase C activity 3/450 26/18639 0.115384615384615 4.77923076923077 0.0240785072364576 0.174507119455976 GO:0005227 calcium-activated cation channel activity 3/450 26/18639 0.115384615384615 4.77923076923077 0.0240785072364576 0.174507119455976 GO:0005085 guanyl-nucleotide exchange factor activity 11/450 230/18639 0.0478260869565217 1.98095652173913 0.0244077087986113 0.175087951892079 GO:0035255 ionotropic glutamate receptor binding 3/450 27/18639 0.111111111111111 4.60222222222222 0.0266148679410458 0.188992446086416 GO:0015108 chloride transmembrane transporter activity 7/450 121/18639 0.0578512396694215 2.39619834710744 0.0275128532044944 0.189009951783051 GO:0045294 alpha-catenin binding 2/450 11/18639 0.181818181818182 7.53090909090909 0.0276927809867059 0.189009951783051 GO:0050998 nitric-oxide synthase binding 2/450 11/18639 0.181818181818182 7.53090909090909 0.0276927809867059 0.189009951783051 GO:0097493 structural molecule activity conferring elasticity 2/450 11/18639 0.181818181818182 7.53090909090909 0.0276927809867059 0.189009951783051 GO:0004725 protein tyrosine phosphatase activity 6/450 98/18639 0.0612244897959184 2.53591836734694 0.031419028928715 0.212380551316218 GO:0004629 phospholipase C activity 3/450 29/18639 0.103448275862069 4.2848275862069 0.0320983314979653 0.214897808234326 GO:0015269 calcium-activated potassium channel activity 2/450 12/18639 0.166666666666667 6.90333333333333 0.0327084857483256 0.214897808234326 GO:0045295 gamma-catenin binding 2/450 12/18639 0.166666666666667 6.90333333333333 0.0327084857483256 0.214897808234326 GO:0022839 monoatomic ion-gated channel activity 3/450 30/18639 0.1 4.142 0.0350439672406353 0.228110268242284 GO:0035591 signaling adaptor activity 7/450 129/18639 0.0542635658914729 2.24759689922481 0.037089031638559 0.23920724075144 GO:0008035 high-density lipoprotein particle binding 2/450 13/18639 0.153846153846154 6.37230769230769 0.0380485637501401 0.240974237084221 GO:0031994 insulin-like growth factor I binding 2/450 13/18639 0.153846153846154 6.37230769230769 0.0380485637501401 0.240974237084221 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 4/450 54/18639 0.0740740740740741 3.06814814814815 0.0411451328647251 0.258259182177694 GO:0044548 S100 protein binding 2/450 14/18639 0.142857142857143 5.91714285714286 0.0436945030863763 0.271833943979845 GO:0044325 transmembrane transporter binding 7/450 136/18639 0.0514705882352941 2.13191176470588 0.0470809783538088 0.287808067675892 GO:0140789 histone phosphatase activity 7/450 136/18639 0.0514705882352941 2.13191176470588 0.0470809783538088 0.287808067675892 GO:0019825 oxygen binding 3/450 34/18639 0.0882352941176471 3.65470588235294 0.0481589397280852 0.291859781283137 GO:0016874 ligase activity 8/450 167/18639 0.0479041916167665 1.98419161676647 0.0500502275223964 0.300234927418703 GO:0005254 chloride channel activity 5/450 83/18639 0.0602409638554217 2.49518072289157 0.0503950518284594 0.300234927418703 GO:0005201 extracellular matrix structural constituent 8/450 168/18639 0.0476190476190476 1.97238095238095 0.0515004208324491 0.304241981892536 GO:1902936 phosphatidylinositol bisphosphate binding 6/450 111/18639 0.0540540540540541 2.23891891891892 0.0523512866986967 0.306691287909865 GO:0005521 lamin binding 2/450 16/18639 0.125 5.1775 0.0558334018113219 0.32172853666688 GO:0015378 sodium:chloride symporter activity 2/450 16/18639 0.125 5.1775 0.0558334018113219 0.32172853666688 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/450 86/18639 0.0581395348837209 2.40813953488372 0.0570858292815426 0.326271040527841 GO:0008201 heparin binding 8/450 172/18639 0.0465116279069767 1.92651162790698 0.0575706441062251 0.32638840973126 GO:0042578 phosphoric ester hydrolase activity 14/450 363/18639 0.0385674931129477 1.59746556473829 0.0583994442181782 0.328438474283034 GO:0008081 phosphoric diester hydrolase activity 5/450 87/18639 0.0574712643678161 2.38045977011494 0.0594240607485422 0.331548529414485 GO:0016651 oxidoreductase activity, acting on NAD(P)H 5/450 88/18639 0.0568181818181818 2.35340909090909 0.0618161888171216 0.337487802370133 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/450 17/18639 0.117647058823529 4.87294117647059 0.0622927529047863 0.337487802370133 GO:0019198 transmembrane receptor protein phosphatase activity 2/450 17/18639 0.117647058823529 4.87294117647059 0.0622927529047863 0.337487802370133 GO:0004721 phosphoprotein phosphatase activity 8/450 175/18639 0.0457142857142857 1.89348571428571 0.0624088396986021 0.337487802370133 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/450 89/18639 0.0561797752808989 2.32696629213483 0.0642621130717848 0.342244435526248 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/450 89/18639 0.0561797752808989 2.32696629213483 0.0642621130717848 0.342244435526248 GO:0004706 JUN kinase kinase kinase activity 2/450 18/18639 0.111111111111111 4.60222222222222 0.0689907049075739 0.359262707777959 GO:0015373 monoatomic anion:sodium symporter activity 2/450 18/18639 0.111111111111111 4.60222222222222 0.0689907049075739 0.359262707777959 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/450 18/18639 0.111111111111111 4.60222222222222 0.0689907049075739 0.359262707777959 GO:0008509 monoatomic anion transmembrane transporter activity 7/450 149/18639 0.0469798657718121 1.94590604026846 0.0698381351507545 0.361001536845444 GO:0005520 insulin-like growth factor binding 2/450 19/18639 0.105263157894737 4.36 0.0759120298867716 0.383929187125183 GO:0008381 mechanosensitive monoatomic ion channel activity 2/450 19/18639 0.105263157894737 4.36 0.0759120298867716 0.383929187125183 GO:0050145 nucleoside monophosphate kinase activity 2/450 19/18639 0.105263157894737 4.36 0.0759120298867716 0.383929187125183 GO:1901981 phosphatidylinositol phosphate binding 8/450 185/18639 0.0432432432432432 1.79113513513514 0.0803255441376196 0.40334898234819 GO:0015631 tubulin binding 14/450 385/18639 0.0363636363636364 1.50618181818182 0.084919692650346 0.420651742309356 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/450 43/18639 0.0697674418604651 2.88976744186047 0.0849680617466978 0.420651742309356 GO:0042626 ATPase-coupled transmembrane transporter activity 5/450 98/18639 0.0510204081632653 2.11326530612245 0.0886650114974898 0.435122495309747 GO:0019205 nucleobase-containing compound kinase activity 3/450 44/18639 0.0681818181818182 2.82409090909091 0.0896288283911997 0.435122495309747 GO:0009975 cyclase activity 2/450 21/18639 0.0952380952380952 3.9447619047619 0.0903668340188095 0.435122495309747 GO:0010314 phosphatidylinositol-5-phosphate binding 2/450 21/18639 0.0952380952380952 3.9447619047619 0.0903668340188095 0.435122495309747 GO:0015079 potassium ion transmembrane transporter activity 7/450 160/18639 0.04375 1.812125 0.0934461569410182 0.446888764146502 GO:0005178 integrin binding 7/450 161/18639 0.0434782608695652 1.80086956521739 0.0957889017579927 0.454997283350465 GO:0008093 cytoskeletal anchor activity 2/450 22/18639 0.0909090909090909 3.76545454545455 0.0978727458772181 0.458696935677895 GO:0015377 chloride:monoatomic cation symporter activity 2/450 22/18639 0.0909090909090909 3.76545454545455 0.0978727458772181 0.458696935677895 GO:0005253 monoatomic anion channel activity 5/450 103/18639 0.0485436893203883 2.01067961165049 0.104028154066905 0.484316505357845 GO:0015103 inorganic anion transmembrane transporter activity 7/450 165/18639 0.0424242424242424 1.75721212121212 0.10548197960386 0.487854155667851 GO:0016879 ligase activity, forming carbon-nitrogen bonds 3/450 48/18639 0.0625 2.58875 0.109289245055893 0.502159080224137 GO:0019838 growth factor binding 6/450 136/18639 0.0441176470588235 1.82735294117647 0.111867835147405 0.507415529524556 GO:0030215 semaphorin receptor binding 2/450 24/18639 0.0833333333333333 3.45166666666667 0.113376720044619 0.507415529524556 GO:0035035 histone acetyltransferase binding 2/450 24/18639 0.0833333333333333 3.45166666666667 0.113376720044619 0.507415529524556 GO:0070300 phosphatidic acid binding 2/450 24/18639 0.0833333333333333 3.45166666666667 0.113376720044619 0.507415529524556 GO:0001222 transcription corepressor binding 3/450 49/18639 0.0612244897959184 2.53591836734694 0.114444330814115 0.507415529524556 GO:0016922 nuclear receptor binding 6/450 137/18639 0.0437956204379562 1.81401459854015 0.114763967559608 0.507415529524556 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/450 25/18639 0.08 3.3136 0.121350379065784 0.53318322802029 GO:0008066 glutamate receptor activity 2/450 26/18639 0.0769230769230769 3.18615384615385 0.129456368384895 0.555747107959676 GO:0043548 phosphatidylinositol 3-kinase binding 2/450 26/18639 0.0769230769230769 3.18615384615385 0.129456368384895 0.555747107959676 GO:0050681 nuclear androgen receptor binding 2/450 26/18639 0.0769230769230769 3.18615384615385 0.129456368384895 0.555747107959676 GO:0005080 protein kinase C binding 3/450 52/18639 0.0576923076923077 2.38961538461538 0.130438510403053 0.555747107959676 GO:0030159 signaling receptor complex adaptor activity 3/450 52/18639 0.0576923076923077 2.38961538461538 0.130438510403053 0.555747107959676 GO:0005544 calcium-dependent phospholipid binding 3/450 53/18639 0.0566037735849057 2.34452830188679 0.135936269529544 0.572795033726174 GO:0019903 protein phosphatase binding 6/450 144/18639 0.0416666666666667 1.72583333333333 0.136069375010343 0.572795033726174 GO:0015252 proton channel activity 2/450 27/18639 0.0740740740740741 3.06814814814815 0.137683688420403 0.576140672378234 GO:0030165 PDZ domain binding 4/450 83/18639 0.0481927710843374 1.99614457831325 0.140938796478704 0.586272035056382 GO:0045499 chemorepellent activity 2/450 28/18639 0.0714285714285714 2.95857142857143 0.14602179144404 0.600311809269941 GO:0051393 alpha-actinin binding 2/450 28/18639 0.0714285714285714 2.95857142857143 0.14602179144404 0.600311809269941 GO:1990782 protein tyrosine kinase binding 5/450 117/18639 0.0427350427350427 1.77008547008547 0.153318169658905 0.626643449245408 GO:0004181 metallocarboxypeptidase activity 2/450 29/18639 0.0689655172413793 2.85655172413793 0.15446056625486 0.627663457093448 GO:0001968 fibronectin binding 2/450 30/18639 0.0666666666666667 2.76133333333333 0.162990323327305 0.658518375282156 GO:0004879 nuclear receptor activity 3/450 59/18639 0.0508474576271186 2.10610169491525 0.170460035741112 0.680871620034101 GO:0015459 potassium channel regulator activity 3/450 59/18639 0.0508474576271186 2.10610169491525 0.170460035741112 0.680871620034101 GO:0098531 ligand-modulated transcription factor activity 3/450 60/18639 0.05 2.071 0.176442387618564 0.699078877574758 GO:0019902 phosphatase binding 7/450 190/18639 0.0368421052631579 1.526 0.177007169570849 0.699078877574758 GO:0071813 lipoprotein particle binding 2/450 32/18639 0.0625 2.58875 0.180286048627647 0.700916960196352 GO:0071814 protein-lipid complex binding 2/450 32/18639 0.0625 2.58875 0.180286048627647 0.700916960196352 GO:0005267 potassium channel activity 5/450 124/18639 0.0403225806451613 1.67016129032258 0.181020001028819 0.700916960196352 GO:0051213 dioxygenase activity 4/450 93/18639 0.043010752688172 1.78150537634409 0.187368240230264 0.700916960196352 GO:0030296 protein tyrosine kinase activator activity 2/450 33/18639 0.0606060606060606 2.51030303030303 0.189034618875387 0.700916960196352 GO:0042562 hormone binding 4/450 94/18639 0.0425531914893617 1.76255319148936 0.192260470588882 0.700916960196352 GO:0000287 magnesium ion binding 8/450 230/18639 0.0347826086956522 1.44069565217391 0.193704123502655 0.700916960196352 GO:0005216 monoatomic ion channel activity 14/450 448/18639 0.03125 1.294375 0.19714136122974 0.700916960196352 GO:0004867 serine-type endopeptidase inhibitor activity 4/450 95/18639 0.0421052631578947 1.744 0.197192448262732 0.700916960196352 GO:0008376 acetylgalactosaminyltransferase activity 2/450 34/18639 0.0588235294117647 2.43647058823529 0.197839348822093 0.700916960196352 GO:0016758 hexosyltransferase activity 7/450 197/18639 0.0355329949238579 1.47177664974619 0.200041310909987 0.700916960196352 GO:0005154 epidermal growth factor receptor binding 2/450 35/18639 0.0571428571428571 2.36685714285714 0.20669245018103 0.700916960196352 GO:0008235 metalloexopeptidase activity 3/450 66/18639 0.0454545454545455 1.88272727272727 0.21344111138755 0.700916960196352 GO:0016791 phosphatase activity 9/450 273/18639 0.032967032967033 1.36549450549451 0.215952825271956 0.700916960196352 GO:0005337 nucleoside transmembrane transporter activity 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0005345 purine nucleobase transmembrane transporter activity 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0005522 profilin binding 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0008401 retinoic acid 4-hydroxylase activity 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0016783 sulfurtransferase activity 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0019531 oxalate transmembrane transporter activity 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0051864 histone H3K36 demethylase activity 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0070097 delta-catenin binding 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0070513 death domain binding 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0070739 protein-glutamic acid ligase activity 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0070740 tubulin-glutamic acid ligase activity 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0141109 transporter activator activity 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:1990763 arrestin family protein binding 1/450 10/18639 0.1 4.142 0.216865788274519 0.700916960196352 GO:1901681 sulfur compound binding 9/450 275/18639 0.0327272727272727 1.35556363636364 0.22190896893032 0.700916960196352 GO:0003714 transcription corepressor activity 7/450 204/18639 0.0343137254901961 1.42127450980392 0.224167659272062 0.700916960196352 GO:0019213 deacetylase activity 2/450 37/18639 0.0540540540540541 2.23891891891892 0.224514310927046 0.700916960196352 GO:0042805 actinin binding 2/450 37/18639 0.0540540540540541 2.23891891891892 0.224514310927046 0.700916960196352 GO:0008017 microtubule binding 9/450 276/18639 0.0326086956521739 1.35065217391304 0.224910583648516 0.700916960196352 GO:0005539 glycosaminoglycan binding 8/450 242/18639 0.0330578512396694 1.36925619834711 0.231692552718732 0.700916960196352 GO:0051020 GTPase binding 10/450 315/18639 0.0317460317460317 1.31492063492063 0.232297820805647 0.700916960196352 GO:0098960 postsynaptic neurotransmitter receptor activity 3/450 69/18639 0.0434782608695652 1.80086956521739 0.232523900766973 0.700916960196352 GO:0000146 microfilament motor activity 2/450 38/18639 0.0526315789473684 2.18 0.233469155348991 0.700916960196352 GO:0000099 sulfur amino acid transmembrane transporter activity 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0002162 dystroglycan binding 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0004016 adenylate cyclase activity 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0008432 JUN kinase binding 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0008503 benzodiazepine receptor activity 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0008526 phosphatidylinositol transfer activity 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0015205 nucleobase transmembrane transporter activity 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0019206 nucleoside kinase activity 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0031731 CCR6 chemokine receptor binding 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0034056 estrogen response element binding 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0047676 arachidonate-CoA ligase activity 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0140031 phosphorylation-dependent protein binding 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/450 11/18639 0.0909090909090909 3.76545454545455 0.2357830890033 0.700916960196352 GO:0016782 transferase activity, transferring sulphur-containing groups 3/450 70/18639 0.0428571428571429 1.77514285714286 0.238953113085665 0.700916960196352 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/450 39/18639 0.0512820512820513 2.12410256410256 0.242444518559744 0.700916960196352 GO:0031267 small GTPase binding 9/450 283/18639 0.0318021201413428 1.31724381625442 0.246337775056552 0.700916960196352 GO:0004300 enoyl-CoA hydratase activity 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0005025 transforming growth factor beta receptor activity, type I 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0005026 transforming growth factor beta receptor activity, type II 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0005095 GTPase inhibitor activity 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0008504 monoamine transmembrane transporter activity 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0015132 prostaglandin transmembrane transporter activity 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0016208 AMP binding 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0016361 activin receptor activity, type I 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0016362 activin receptor activity, type II 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0017002 activin receptor activity 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0017166 vinculin binding 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0140900 chloride:bicarbonate antiporter activity 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/450 12/18639 0.0833333333333333 3.45166666666667 0.254244416571934 0.700916960196352 GO:0020037 heme binding 5/450 142/18639 0.0352112676056338 1.45845070422535 0.259335174535555 0.703673891769166 GO:0001727 lipid kinase activity 2/450 41/18639 0.0487804878048781 2.02048780487805 0.260432308116567 0.703673891769166 GO:0017080 sodium channel regulator activity 2/450 41/18639 0.0487804878048781 2.02048780487805 0.260432308116567 0.703673891769166 GO:0005319 lipid transporter activity 6/450 178/18639 0.0337078651685393 1.3961797752809 0.260880777463035 0.703673891769166 GO:0005496 steroid binding 4/450 108/18639 0.037037037037037 1.53407407407407 0.264286109634365 0.703673891769166 GO:0019955 cytokine binding 5/450 144/18639 0.0347222222222222 1.43819444444444 0.268514301279656 0.703673891769166 GO:0035198 miRNA binding 2/450 42/18639 0.0476190476190476 1.97238095238095 0.269433192423994 0.703673891769166 GO:0048487 beta-tubulin binding 2/450 42/18639 0.0476190476190476 1.97238095238095 0.269433192423994 0.703673891769166 GO:0004620 phospholipase activity 4/450 109/18639 0.036697247706422 1.52 0.26962761462456 0.703673891769166 GO:0017154 semaphorin receptor activity 1/450 13/18639 0.0769230769230769 3.18615384615385 0.272260737640417 0.703673891769166 GO:0035325 Toll-like receptor binding 1/450 13/18639 0.0769230769230769 3.18615384615385 0.272260737640417 0.703673891769166 GO:0043560 insulin receptor substrate binding 1/450 13/18639 0.0769230769230769 3.18615384615385 0.272260737640417 0.703673891769166 GO:0046974 histone H3K9 methyltransferase activity 1/450 13/18639 0.0769230769230769 3.18615384615385 0.272260737640417 0.703673891769166 GO:0070123 transforming growth factor beta receptor activity, type III 1/450 13/18639 0.0769230769230769 3.18615384615385 0.272260737640417 0.703673891769166 GO:0071714 icosanoid transmembrane transporter activity 1/450 13/18639 0.0769230769230769 3.18615384615385 0.272260737640417 0.703673891769166 GO:0071837 HMG box domain binding 1/450 13/18639 0.0769230769230769 3.18615384615385 0.272260737640417 0.703673891769166 GO:0140333 glycerophospholipid flippase activity 1/450 13/18639 0.0769230769230769 3.18615384615385 0.272260737640417 0.703673891769166 GO:0015293 symporter activity 5/450 146/18639 0.0342465753424658 1.41849315068493 0.277763763054933 0.70681064931933 GO:0003713 transcription coactivator activity 8/450 256/18639 0.03125 1.294375 0.278964533896949 0.70681064931933 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 14/450 484/18639 0.0289256198347107 1.19809917355372 0.282214048074098 0.70681064931933 GO:0015085 calcium ion transmembrane transporter activity 5/450 147/18639 0.0340136054421769 1.40884353741497 0.282412741904922 0.70681064931933 GO:0001223 transcription coactivator binding 2/450 44/18639 0.0454545454545455 1.88272727272727 0.28742209448572 0.70681064931933 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/450 44/18639 0.0454545454545455 1.88272727272727 0.28742209448572 0.70681064931933 GO:0043014 alpha-tubulin binding 2/450 44/18639 0.0454545454545455 1.88272727272727 0.28742209448572 0.70681064931933 GO:0004705 JUN kinase activity 1/450 14/18639 0.0714285714285714 2.95857142857143 0.289842755683035 0.70681064931933 GO:0005545 1-phosphatidylinositol binding 1/450 14/18639 0.0714285714285714 2.95857142857143 0.289842755683035 0.70681064931933 GO:0008195 phosphatidate phosphatase activity 1/450 14/18639 0.0714285714285714 2.95857142857143 0.289842755683035 0.70681064931933 GO:0015386 potassium:proton antiporter activity 1/450 14/18639 0.0714285714285714 2.95857142857143 0.289842755683035 0.70681064931933 GO:0032454 histone H3K9 demethylase activity 1/450 14/18639 0.0714285714285714 2.95857142857143 0.289842755683035 0.70681064931933 GO:0042813 Wnt receptor activity 1/450 14/18639 0.0714285714285714 2.95857142857143 0.289842755683035 0.70681064931933 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/450 14/18639 0.0714285714285714 2.95857142857143 0.289842755683035 0.70681064931933 GO:0098821 BMP receptor activity 1/450 14/18639 0.0714285714285714 2.95857142857143 0.289842755683035 0.70681064931933 GO:0046873 metal ion transmembrane transporter activity 13/450 450/18639 0.0288888888888889 1.19657777777778 0.293478994846195 0.70681064931933 GO:0051539 4 iron, 4 sulfur cluster binding 2/450 45/18639 0.0444444444444444 1.84088888888889 0.296400137845256 0.70681064931933 GO:0015370 solute:sodium symporter activity 3/450 79/18639 0.0379746835443038 1.57291139240506 0.297858184362834 0.70681064931933 GO:0001216 DNA-binding transcription activator activity 14/450 491/18639 0.0285132382892057 1.1810183299389 0.300035546180121 0.70681064931933 GO:0001221 transcription coregulator binding 4/450 115/18639 0.0347826086956522 1.44069565217391 0.302029138090797 0.70681064931933 GO:0004180 carboxypeptidase activity 2/450 46/18639 0.0434782608695652 1.80086956521739 0.305360996267445 0.70681064931933 GO:0046906 tetrapyrrole binding 5/450 152/18639 0.0328947368421053 1.3625 0.305866416221393 0.70681064931933 GO:0004129 cytochrome-c oxidase activity 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0004467 long-chain fatty acid-CoA ligase activity 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0005041 low-density lipoprotein particle receptor activity 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0015116 sulfate transmembrane transporter activity 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0045504 dynein heavy chain binding 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0050780 dopamine receptor binding 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0051371 muscle alpha-actinin binding 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0120283 protein serine/threonine kinase binding 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0140776 protein-containing complex destabilizing activity 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0141050 histone H3K deacetylase activity 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0141051 histone H4K deacetylase activity 1/450 15/18639 0.0666666666666667 2.76133333333333 0.307000917290694 0.70681064931933 GO:0003712 transcription coregulator activity 14/450 495/18639 0.0282828282828283 1.17147474747475 0.310364274895622 0.70681064931933 GO:0001618 virus receptor activity 3/450 81/18639 0.037037037037037 1.53407407407407 0.311098710480209 0.70681064931933 GO:0030971 receptor tyrosine kinase binding 3/450 81/18639 0.037037037037037 1.53407407407407 0.311098710480209 0.70681064931933 GO:0140272 exogenous protein binding 3/450 82/18639 0.0365853658536585 1.51536585365854 0.317726183947065 0.70681064931933 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0004707 MAP kinase activity 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0004708 MAP kinase kinase activity 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0005024 transforming growth factor beta receptor activity 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0015385 sodium:proton antiporter activity 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0016722 oxidoreductase activity, acting on metal ions 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0034450 ubiquitin-ubiquitin ligase activity 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0140327 flippase activity 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0140328 floppase activity 1/450 16/18639 0.0625 2.58875 0.323745418322652 0.70681064931933 GO:0051117 ATPase binding 3/450 84/18639 0.0357142857142857 1.47928571428571 0.330985286525523 0.720379741261432 GO:0004550 nucleoside diphosphate kinase activity 1/450 17/18639 0.0588235294117647 2.43647058823529 0.340086209911268 0.726688770722254 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/450 17/18639 0.0588235294117647 2.43647058823529 0.340086209911268 0.726688770722254 GO:0030169 low-density lipoprotein particle binding 1/450 17/18639 0.0588235294117647 2.43647058823529 0.340086209911268 0.726688770722254 GO:0038191 neuropilin binding 1/450 17/18639 0.0588235294117647 2.43647058823529 0.340086209911268 0.726688770722254 GO:0046965 nuclear retinoid X receptor binding 1/450 17/18639 0.0588235294117647 2.43647058823529 0.340086209911268 0.726688770722254 GO:0048038 quinone binding 1/450 17/18639 0.0588235294117647 2.43647058823529 0.340086209911268 0.726688770722254 GO:0099106 ion channel regulator activity 5/450 160/18639 0.03125 1.294375 0.343916162174354 0.732645642450215 GO:0004866 endopeptidase inhibitor activity 5/450 161/18639 0.031055900621118 1.28633540372671 0.348700867264937 0.738322129909277 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/450 18/18639 0.0555555555555556 2.30111111111111 0.35603300432325 0.738322129909277 GO:0004970 glutamate-gated receptor activity 1/450 18/18639 0.0555555555555556 2.30111111111111 0.35603300432325 0.738322129909277 GO:0015280 ligand-gated sodium channel activity 1/450 18/18639 0.0555555555555556 2.30111111111111 0.35603300432325 0.738322129909277 GO:0022851 GABA-gated chloride ion channel activity 1/450 18/18639 0.0555555555555556 2.30111111111111 0.35603300432325 0.738322129909277 GO:0030228 lipoprotein particle receptor activity 1/450 18/18639 0.0555555555555556 2.30111111111111 0.35603300432325 0.738322129909277 GO:0035615 clathrin adaptor activity 1/450 18/18639 0.0555555555555556 2.30111111111111 0.35603300432325 0.738322129909277 GO:0050811 GABA receptor binding 1/450 18/18639 0.0555555555555556 2.30111111111111 0.35603300432325 0.738322129909277 GO:0070064 proline-rich region binding 1/450 18/18639 0.0555555555555556 2.30111111111111 0.35603300432325 0.738322129909277 GO:0015081 sodium ion transmembrane transporter activity 5/450 164/18639 0.0304878048780488 1.26280487804878 0.363074396209478 0.74213489295064 GO:0008146 sulfotransferase activity 2/450 53/18639 0.0377358490566038 1.56301886792453 0.367263484084734 0.74213489295064 GO:0051018 protein kinase A binding 2/450 53/18639 0.0377358490566038 1.56301886792453 0.367263484084734 0.74213489295064 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/450 53/18639 0.0377358490566038 1.56301886792453 0.367263484084734 0.74213489295064 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/450 53/18639 0.0377358490566038 1.56301886792453 0.367263484084734 0.74213489295064 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/450 19/18639 0.0526315789473684 2.18 0.371595280680832 0.74213489295064 GO:0004890 GABA-A receptor activity 1/450 19/18639 0.0526315789473684 2.18 0.371595280680832 0.74213489295064 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/450 19/18639 0.0526315789473684 2.18 0.371595280680832 0.74213489295064 GO:0015245 fatty acid transmembrane transporter activity 1/450 19/18639 0.0526315789473684 2.18 0.371595280680832 0.74213489295064 GO:0022821 solute:potassium antiporter activity 1/450 19/18639 0.0526315789473684 2.18 0.371595280680832 0.74213489295064 GO:0030506 ankyrin binding 1/450 19/18639 0.0526315789473684 2.18 0.371595280680832 0.74213489295064 GO:0042577 lipid phosphatase activity 1/450 19/18639 0.0526315789473684 2.18 0.371595280680832 0.74213489295064 GO:1990380 K48-linked deubiquitinase activity 1/450 19/18639 0.0526315789473684 2.18 0.371595280680832 0.74213489295064 GO:0140463 chromatin-protein adaptor activity 2/450 54/18639 0.037037037037037 1.53407407407407 0.375946225059334 0.74867466549013 GO:0016247 channel regulator activity 5/450 168/18639 0.0297619047619048 1.2327380952381 0.382256667851548 0.74867466549013 GO:0016298 lipase activity 4/450 130/18639 0.0307692307692308 1.27446153846154 0.384243329853427 0.74867466549013 GO:0001972 retinoic acid binding 1/450 20/18639 0.05 2.071 0.386782290546226 0.74867466549013 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/450 20/18639 0.05 2.071 0.386782290546226 0.74867466549013 GO:0030627 pre-mRNA 5'-splice site binding 1/450 20/18639 0.05 2.071 0.386782290546226 0.74867466549013 GO:0030414 peptidase inhibitor activity 5/450 169/18639 0.029585798816568 1.22544378698225 0.387050546417869 0.74867466549013 GO:0015291 secondary active transmembrane transporter activity 8/450 287/18639 0.0278745644599303 1.15456445993031 0.390459109999101 0.74867466549013 GO:0141108 transporter regulator activity 5/450 170/18639 0.0294117647058824 1.21823529411765 0.391842340723358 0.74867466549013 GO:0030170 pyridoxal phosphate binding 2/450 56/18639 0.0357142857142857 1.47928571428571 0.393160757350271 0.74867466549013 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/450 56/18639 0.0357142857142857 1.47928571428571 0.393160757350271 0.74867466549013 GO:0170055 lipid transmembrane transporter activity 2/450 56/18639 0.0357142857142857 1.47928571428571 0.393160757350271 0.74867466549013 GO:0005123 death receptor binding 1/450 21/18639 0.0476190476190476 1.97238095238095 0.401603063372597 0.74867466549013 GO:0015174 basic amino acid transmembrane transporter activity 1/450 21/18639 0.0476190476190476 1.97238095238095 0.401603063372597 0.74867466549013 GO:0036122 BMP binding 1/450 21/18639 0.0476190476190476 1.97238095238095 0.401603063372597 0.74867466549013 GO:0051010 microtubule plus-end binding 1/450 21/18639 0.0476190476190476 1.97238095238095 0.401603063372597 0.74867466549013 GO:0140312 cargo adaptor activity 1/450 21/18639 0.0476190476190476 1.97238095238095 0.401603063372597 0.74867466549013 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/450 57/18639 0.0350877192982456 1.45333333333333 0.401687358209018 0.74867466549013 GO:0070279 vitamin B6 binding 2/450 57/18639 0.0350877192982456 1.45333333333333 0.401687358209018 0.74867466549013 GO:0004896 cytokine receptor activity 3/450 96/18639 0.03125 1.294375 0.409879454520475 0.74867466549013 GO:0061980 regulatory RNA binding 2/450 58/18639 0.0344827586206897 1.42827586206897 0.41015697805852 0.74867466549013 GO:0004407 histone deacetylase activity 1/450 22/18639 0.0454545454545455 1.88272727272727 0.416066411824757 0.74867466549013 GO:0008649 rRNA methyltransferase activity 1/450 22/18639 0.0454545454545455 1.88272727272727 0.416066411824757 0.74867466549013 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/450 22/18639 0.0454545454545455 1.88272727272727 0.416066411824757 0.74867466549013 GO:0016881 acid-amino acid ligase activity 1/450 22/18639 0.0454545454545455 1.88272727272727 0.416066411824757 0.74867466549013 GO:0033558 protein lysine deacetylase activity 1/450 22/18639 0.0454545454545455 1.88272727272727 0.416066411824757 0.74867466549013 GO:0050321 tau-protein kinase activity 1/450 22/18639 0.0454545454545455 1.88272727272727 0.416066411824757 0.74867466549013 GO:0140517 protein-RNA adaptor activity 1/450 22/18639 0.0454545454545455 1.88272727272727 0.416066411824757 0.74867466549013 GO:0030594 neurotransmitter receptor activity 3/450 97/18639 0.0309278350515464 1.28103092783505 0.416348904856865 0.74867466549013 GO:0002020 protease binding 4/450 136/18639 0.0294117647058824 1.21823529411765 0.416973281271887 0.74867466549013 GO:0099094 ligand-gated monoatomic cation channel activity 4/450 136/18639 0.0294117647058824 1.21823529411765 0.416973281271887 0.74867466549013 GO:0001786 phosphatidylserine binding 2/450 59/18639 0.0338983050847458 1.40406779661017 0.4185673970872 0.74867466549013 GO:0019887 protein kinase regulator activity 7/450 255/18639 0.0274509803921569 1.13701960784314 0.41925580197355 0.74867466549013 GO:0005249 voltage-gated potassium channel activity 3/450 98/18639 0.0306122448979592 1.26795918367347 0.422795308908087 0.74867466549013 GO:0008170 N-methyltransferase activity 3/450 98/18639 0.0306122448979592 1.26795918367347 0.422795308908087 0.74867466549013 GO:0001664 G protein-coupled receptor binding 8/450 297/18639 0.0269360269360269 1.11569023569024 0.427145177656962 0.74867466549013 GO:0000295 adenine nucleotide transmembrane transporter activity 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0003887 DNA-directed DNA polymerase activity 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0005158 insulin receptor binding 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0005212 structural constituent of eye lens 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0016849 phosphorus-oxygen lyase activity 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0016917 GABA receptor activity 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0017134 fibroblast growth factor binding 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0070577 lysine-acetylated histone binding 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0140102 catalytic activity, acting on a rRNA 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0140103 catalytic activity, acting on a glycoprotein 1/450 23/18639 0.0434782608695652 1.80086956521739 0.430180936972679 0.74867466549013 GO:0030295 protein kinase activator activity 4/450 139/18639 0.0287769784172662 1.19194244604317 0.433197366706526 0.74867466549013 GO:0070851 growth factor receptor binding 4/450 139/18639 0.0287769784172662 1.19194244604317 0.433197366706526 0.74867466549013 GO:0016836 hydro-lyase activity 2/450 61/18639 0.0327868852459016 1.35803278688525 0.435202447309175 0.74867466549013 GO:0005261 monoatomic cation channel activity 9/450 341/18639 0.0263929618768328 1.09319648093842 0.440563765477397 0.74867466549013 GO:0015179 L-amino acid transmembrane transporter activity 2/450 62/18639 0.032258064516129 1.33612903225806 0.443423316633848 0.74867466549013 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/450 24/18639 0.0416666666666667 1.72583333333333 0.443955033360856 0.74867466549013 GO:0015149 hexose transmembrane transporter activity 1/450 24/18639 0.0416666666666667 1.72583333333333 0.443955033360856 0.74867466549013 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/450 24/18639 0.0416666666666667 1.72583333333333 0.443955033360856 0.74867466549013 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/450 24/18639 0.0416666666666667 1.72583333333333 0.443955033360856 0.74867466549013 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/450 24/18639 0.0416666666666667 1.72583333333333 0.443955033360856 0.74867466549013 GO:0048027 mRNA 5'-UTR binding 1/450 24/18639 0.0416666666666667 1.72583333333333 0.443955033360856 0.74867466549013 GO:0050431 transforming growth factor beta binding 1/450 24/18639 0.0416666666666667 1.72583333333333 0.443955033360856 0.74867466549013 GO:0055056 D-glucose transmembrane transporter activity 1/450 24/18639 0.0416666666666667 1.72583333333333 0.443955033360856 0.74867466549013 GO:0140033 acetylation-dependent protein binding 1/450 24/18639 0.0416666666666667 1.72583333333333 0.443955033360856 0.74867466549013 GO:0008238 exopeptidase activity 3/450 102/18639 0.0294117647058824 1.21823529411765 0.448324989951655 0.74867466549013 GO:0015171 amino acid transmembrane transporter activity 3/450 102/18639 0.0294117647058824 1.21823529411765 0.448324989951655 0.74867466549013 GO:0022824 transmitter-gated monoatomic ion channel activity 2/450 63/18639 0.0317460317460317 1.31492063492063 0.451577451068721 0.74867466549013 GO:0022835 transmitter-gated channel activity 2/450 63/18639 0.0317460317460317 1.31492063492063 0.451577451068721 0.74867466549013 GO:1901682 sulfur compound transmembrane transporter activity 2/450 63/18639 0.0317460317460317 1.31492063492063 0.451577451068721 0.74867466549013 GO:0022843 voltage-gated monoatomic cation channel activity 4/450 143/18639 0.027972027972028 1.1586013986014 0.454630933625905 0.74867466549013 GO:0003707 nuclear steroid receptor activity 1/450 25/18639 0.04 1.6568 0.457396893956484 0.74867466549013 GO:0005251 delayed rectifier potassium channel activity 1/450 25/18639 0.04 1.6568 0.457396893956484 0.74867466549013 GO:0015645 fatty acid ligase activity 1/450 25/18639 0.04 1.6568 0.457396893956484 0.74867466549013 GO:0017025 TBP-class protein binding 1/450 25/18639 0.04 1.6568 0.457396893956484 0.74867466549013 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/450 25/18639 0.04 1.6568 0.457396893956484 0.74867466549013 GO:0019707 protein-cysteine S-acyltransferase activity 1/450 25/18639 0.04 1.6568 0.457396893956484 0.74867466549013 GO:0042974 nuclear retinoic acid receptor binding 1/450 25/18639 0.04 1.6568 0.457396893956484 0.74867466549013 GO:0120515 fatty acid-CoA ligase activity 1/450 25/18639 0.04 1.6568 0.457396893956484 0.74867466549013 GO:0008237 metallopeptidase activity 5/450 184/18639 0.0271739130434783 1.12554347826087 0.458340455307892 0.74867466549013 GO:0061135 endopeptidase regulator activity 5/450 184/18639 0.0271739130434783 1.12554347826087 0.458340455307892 0.74867466549013 GO:0008194 UDP-glycosyltransferase activity 4/450 145/18639 0.0275862068965517 1.14262068965517 0.46524834985301 0.74867466549013 GO:0016757 glycosyltransferase activity 7/450 267/18639 0.0262172284644195 1.08591760299625 0.466327050703517 0.74867466549013 GO:0120013 lipid transfer activity 2/450 65/18639 0.0307692307692308 1.27446153846154 0.467679337457912 0.74867466549013 GO:0160215 deacylase activity 2/450 65/18639 0.0307692307692308 1.27446153846154 0.467679337457912 0.74867466549013 GO:0015276 ligand-gated monoatomic ion channel activity 5/450 186/18639 0.0268817204301075 1.11344086021505 0.467695135254201 0.74867466549013 GO:0008143 poly(A) binding 1/450 26/18639 0.0384615384615385 1.59307692307692 0.470514514979347 0.74867466549013 GO:0008157 protein phosphatase 1 binding 1/450 26/18639 0.0384615384615385 1.59307692307692 0.470514514979347 0.74867466549013 GO:0015145 monosaccharide transmembrane transporter activity 1/450 26/18639 0.0384615384615385 1.59307692307692 0.470514514979347 0.74867466549013 GO:0015216 purine nucleotide transmembrane transporter activity 1/450 26/18639 0.0384615384615385 1.59307692307692 0.470514514979347 0.74867466549013 GO:0034237 protein kinase A regulatory subunit binding 1/450 26/18639 0.0384615384615385 1.59307692307692 0.470514514979347 0.74867466549013 GO:0051139 metal cation:proton antiporter activity 1/450 26/18639 0.0384615384615385 1.59307692307692 0.470514514979347 0.74867466549013 GO:0070006 metalloaminopeptidase activity 1/450 26/18639 0.0384615384615385 1.59307692307692 0.470514514979347 0.74867466549013 GO:0120014 phospholipid transfer activity 1/450 26/18639 0.0384615384615385 1.59307692307692 0.470514514979347 0.74867466549013 GO:0004497 monooxygenase activity 3/450 106/18639 0.0283018867924528 1.1722641509434 0.473389138274353 0.74867466549013 GO:0008514 organic anion transmembrane transporter activity 7/450 269/18639 0.0260223048327138 1.077843866171 0.474096691155381 0.74867466549013 GO:0022834 ligand-gated channel activity 5/450 188/18639 0.0265957446808511 1.10159574468085 0.476999985644475 0.74867466549013 GO:0046943 carboxylic acid transmembrane transporter activity 5/450 188/18639 0.0265957446808511 1.10159574468085 0.476999985644475 0.74867466549013 GO:0019209 kinase activator activity 4/450 148/18639 0.027027027027027 1.11945945945946 0.481033695399115 0.74867466549013 GO:0005342 organic acid transmembrane transporter activity 5/450 189/18639 0.0264550264550265 1.0957671957672 0.481632433691651 0.74867466549013 GO:0001671 ATPase activator activity 1/450 27/18639 0.037037037037037 1.53407407407407 0.48331570061623 0.74867466549013 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/450 27/18639 0.037037037037037 1.53407407407407 0.48331570061623 0.74867466549013 GO:0005044 scavenger receptor activity 1/450 27/18639 0.037037037037037 1.53407407407407 0.48331570061623 0.74867466549013 GO:0008266 poly(U) RNA binding 1/450 27/18639 0.037037037037037 1.53407407407407 0.48331570061623 0.74867466549013 GO:0016405 CoA-ligase activity 1/450 27/18639 0.037037037037037 1.53407407407407 0.48331570061623 0.74867466549013 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/450 27/18639 0.037037037037037 1.53407407407407 0.48331570061623 0.74867466549013 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/450 67/18639 0.0298507462686567 1.23641791044776 0.48349686789832 0.74867466549013 GO:0005548 phospholipid transporter activity 2/450 68/18639 0.0294117647058824 1.21823529411765 0.491295952876 0.754443877789379 GO:1990841 promoter-specific chromatin binding 2/450 68/18639 0.0294117647058824 1.21823529411765 0.491295952876 0.754443877789379 GO:0046625 sphingolipid binding 1/450 28/18639 0.0357142857142857 1.47928571428571 0.495808067622607 0.754443877789379 GO:0046875 ephrin receptor binding 1/450 28/18639 0.0357142857142857 1.47928571428571 0.495808067622607 0.754443877789379 GO:0050698 proteoglycan sulfotransferase activity 1/450 28/18639 0.0357142857142857 1.47928571428571 0.495808067622607 0.754443877789379 GO:0051119 sugar transmembrane transporter activity 1/450 28/18639 0.0357142857142857 1.47928571428571 0.495808067622607 0.754443877789379 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/450 28/18639 0.0357142857142857 1.47928571428571 0.495808067622607 0.754443877789379 GO:0141052 histone H3 demethylase activity 1/450 28/18639 0.0357142857142857 1.47928571428571 0.495808067622607 0.754443877789379 GO:0022836 gated channel activity 8/450 318/18639 0.0251572327044025 1.04201257861635 0.503204029403237 0.759847857429547 GO:0097110 scaffold protein binding 2/450 70/18639 0.0285714285714286 1.18342857142857 0.506669532293728 0.759847857429547 GO:0003785 actin monomer binding 1/450 29/18639 0.0344827586206897 1.42827586206897 0.507999049814313 0.759847857429547 GO:0016417 S-acyltransferase activity 1/450 29/18639 0.0344827586206897 1.42827586206897 0.507999049814313 0.759847857429547 GO:0043236 laminin binding 1/450 29/18639 0.0344827586206897 1.42827586206897 0.507999049814313 0.759847857429547 GO:0099604 ligand-gated calcium channel activity 1/450 29/18639 0.0344827586206897 1.42827586206897 0.507999049814313 0.759847857429547 GO:0106222 lncRNA binding 1/450 29/18639 0.0344827586206897 1.42827586206897 0.507999049814313 0.759847857429547 GO:0001217 DNA-binding transcription repressor activity 7/450 278/18639 0.0251798561151079 1.04294964028777 0.508668412347607 0.759847857429547 GO:0005200 structural constituent of cytoskeleton 3/450 112/18639 0.0267857142857143 1.10946428571429 0.509970349773426 0.759847857429547 GO:0005506 iron ion binding 4/450 154/18639 0.025974025974026 1.07584415584416 0.512031581749441 0.759847857429547 GO:0140299 molecular sensor activity 2/450 71/18639 0.028169014084507 1.16676056338028 0.514242211447264 0.759847857429547 GO:0140297 DNA-binding transcription factor binding 12/450 488/18639 0.0245901639344262 1.01852459016393 0.515524217063608 0.759847857429547 GO:0001965 G-protein alpha-subunit binding 1/450 30/18639 0.0333333333333333 1.38066666666667 0.519895902451796 0.759847857429547 GO:0008187 poly-pyrimidine tract binding 1/450 30/18639 0.0333333333333333 1.38066666666667 0.519895902451796 0.759847857429547 GO:0015215 nucleotide transmembrane transporter activity 1/450 30/18639 0.0333333333333333 1.38066666666667 0.519895902451796 0.759847857429547 GO:0031624 ubiquitin conjugating enzyme binding 1/450 30/18639 0.0333333333333333 1.38066666666667 0.519895902451796 0.759847857429547 GO:0032452 histone demethylase activity 1/450 30/18639 0.0333333333333333 1.38066666666667 0.519895902451796 0.759847857429547 GO:0051721 protein phosphatase 2A binding 1/450 30/18639 0.0333333333333333 1.38066666666667 0.519895902451796 0.759847857429547 GO:0070566 adenylyltransferase activity 1/450 30/18639 0.0333333333333333 1.38066666666667 0.519895902451796 0.759847857429547 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/450 73/18639 0.0273972602739726 1.13479452054795 0.52915545668773 0.762547983027017 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/450 31/18639 0.032258064516129 1.33612903225806 0.531505706519542 0.762547983027017 GO:0005452 solute:inorganic anion antiporter activity 1/450 31/18639 0.032258064516129 1.33612903225806 0.531505706519542 0.762547983027017 GO:0016411 acylglycerol O-acyltransferase activity 1/450 31/18639 0.032258064516129 1.33612903225806 0.531505706519542 0.762547983027017 GO:0016878 acid-thiol ligase activity 1/450 31/18639 0.032258064516129 1.33612903225806 0.531505706519542 0.762547983027017 GO:0017147 Wnt-protein binding 1/450 31/18639 0.032258064516129 1.33612903225806 0.531505706519542 0.762547983027017 GO:0070273 phosphatidylinositol-4-phosphate binding 1/450 31/18639 0.032258064516129 1.33612903225806 0.531505706519542 0.762547983027017 GO:0072349 modified amino acid transmembrane transporter activity 1/450 31/18639 0.032258064516129 1.33612903225806 0.531505706519542 0.762547983027017 GO:0140457 protein demethylase activity 1/450 31/18639 0.032258064516129 1.33612903225806 0.531505706519542 0.762547983027017 GO:0015294 solute:monoatomic cation symporter activity 3/450 116/18639 0.0258620689655172 1.07120689655172 0.53360242794083 0.763996958945831 GO:0019207 kinase regulator activity 7/450 287/18639 0.024390243902439 1.01024390243902 0.542440922881813 0.767833535514921 GO:0015106 bicarbonate transmembrane transporter activity 1/450 32/18639 0.03125 1.294375 0.542835372903151 0.767833535514921 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/450 32/18639 0.03125 1.294375 0.542835372903151 0.767833535514921 GO:0043425 bHLH transcription factor binding 1/450 32/18639 0.03125 1.294375 0.542835372903151 0.767833535514921 GO:0070717 poly-purine tract binding 1/450 32/18639 0.03125 1.294375 0.542835372903151 0.767833535514921 GO:0120015 sterol transfer activity 1/450 32/18639 0.03125 1.294375 0.542835372903151 0.767833535514921 GO:0003924 GTPase activity 8/450 331/18639 0.0241691842900302 1.00108761329305 0.548747746627868 0.772590927511831 GO:0017022 myosin binding 2/450 76/18639 0.0263157894736842 1.09 0.550935758597115 0.772590927511831 GO:0051536 iron-sulfur cluster binding 2/450 76/18639 0.0263157894736842 1.09 0.550935758597115 0.772590927511831 GO:0008083 growth factor activity 4/450 162/18639 0.0246913580246914 1.02271604938272 0.551989711183973 0.772590927511831 GO:0071889 14-3-3 protein binding 1/450 33/18639 0.0303030303030303 1.25515151515152 0.553891646466519 0.772590927511831 GO:0140311 protein sequestering activity 1/450 33/18639 0.0303030303030303 1.25515151515152 0.553891646466519 0.772590927511831 GO:0140416 transcription regulator inhibitor activity 1/450 33/18639 0.0303030303030303 1.25515151515152 0.553891646466519 0.772590927511831 GO:0051540 metal cluster binding 2/450 77/18639 0.025974025974026 1.07584415584416 0.558036682005125 0.776831262276441 GO:0015020 glucuronosyltransferase activity 1/450 34/18639 0.0294117647058824 1.21823529411765 0.564681110031502 0.782703468944434 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/450 34/18639 0.0294117647058824 1.21823529411765 0.564681110031502 0.782703468944434 GO:0016835 carbon-oxygen lyase activity 2/450 79/18639 0.0253164556962025 1.04860759493671 0.571997639821885 0.782703468944434 GO:0033293 monocarboxylic acid binding 2/450 79/18639 0.0253164556962025 1.04860759493671 0.571997639821885 0.782703468944434 GO:0016229 steroid dehydrogenase activity 1/450 35/18639 0.0285714285714286 1.18342857142857 0.575210188262398 0.782703468944434 GO:0034061 DNA polymerase activity 1/450 35/18639 0.0285714285714286 1.18342857142857 0.575210188262398 0.782703468944434 GO:0043015 gamma-tubulin binding 1/450 35/18639 0.0285714285714286 1.18342857142857 0.575210188262398 0.782703468944434 GO:0061631 ubiquitin conjugating enzyme activity 1/450 35/18639 0.0285714285714286 1.18342857142857 0.575210188262398 0.782703468944434 GO:0004190 aspartic-type endopeptidase activity 1/450 36/18639 0.0277777777777778 1.15055555555556 0.585485151457513 0.782703468944434 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/450 36/18639 0.0277777777777778 1.15055555555556 0.585485151457513 0.782703468944434 GO:0005484 SNAP receptor activity 1/450 36/18639 0.0277777777777778 1.15055555555556 0.585485151457513 0.782703468944434 GO:0016409 palmitoyltransferase activity 1/450 36/18639 0.0277777777777778 1.15055555555556 0.585485151457513 0.782703468944434 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/450 36/18639 0.0277777777777778 1.15055555555556 0.585485151457513 0.782703468944434 GO:0033192 calmodulin-dependent protein phosphatase activity 2/450 81/18639 0.0246913580246914 1.02271604938272 0.585635881457713 0.782703468944434 GO:0140791 histone H2AXS140 phosphatase activity 2/450 81/18639 0.0246913580246914 1.02271604938272 0.585635881457713 0.782703468944434 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/450 81/18639 0.0246913580246914 1.02271604938272 0.585635881457713 0.782703468944434 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/450 81/18639 0.0246913580246914 1.02271604938272 0.585635881457713 0.782703468944434 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/450 81/18639 0.0246913580246914 1.02271604938272 0.585635881457713 0.782703468944434 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/450 81/18639 0.0246913580246914 1.02271604938272 0.585635881457713 0.782703468944434 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/450 81/18639 0.0246913580246914 1.02271604938272 0.585635881457713 0.782703468944434 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/450 81/18639 0.0246913580246914 1.02271604938272 0.585635881457713 0.782703468944434 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/450 82/18639 0.024390243902439 1.01024390243902 0.592333623895479 0.788656321209322 GO:0033549 MAP kinase phosphatase activity 2/450 82/18639 0.024390243902439 1.01024390243902 0.592333623895479 0.788656321209322 GO:0043394 proteoglycan binding 1/450 37/18639 0.027027027027027 1.11945945945946 0.595512119250026 0.789896263835412 GO:0070001 aspartic-type peptidase activity 1/450 37/18639 0.027027027027027 1.11945945945946 0.595512119250026 0.789896263835412 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/450 83/18639 0.0240963855421687 0.998072289156626 0.598950362486056 0.792656844544481 GO:0031490 chromatin DNA binding 3/450 128/18639 0.0234375 0.97078125 0.600435545654101 0.792656844544481 GO:0005244 voltage-gated monoatomic ion channel activity 4/450 173/18639 0.023121387283237 0.957687861271676 0.603969504304845 0.792656844544481 GO:0005501 retinoid binding 1/450 38/18639 0.0263157894736842 1.09 0.605297064220324 0.792656844544481 GO:0019840 isoprenoid binding 1/450 38/18639 0.0263157894736842 1.09 0.605297064220324 0.792656844544481 GO:0004860 protein kinase inhibitor activity 2/450 84/18639 0.0238095238095238 0.986190476190476 0.605486096046069 0.792656844544481 GO:0017018 myosin phosphatase activity 2/450 84/18639 0.0238095238095238 0.986190476190476 0.605486096046069 0.792656844544481 GO:0022832 voltage-gated channel activity 4/450 175/18639 0.0228571428571429 0.946742857142857 0.613019656090377 0.801027543181292 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/450 39/18639 0.0256410256410256 1.06205128205128 0.614845815421919 0.801923206385174 GO:0004177 aminopeptidase activity 1/450 40/18639 0.025 1.0355 0.624164061823001 0.805114376993706 GO:0015144 carbohydrate transmembrane transporter activity 1/450 40/18639 0.025 1.0355 0.624164061823001 0.805114376993706 GO:0030331 nuclear estrogen receptor binding 1/450 40/18639 0.025 1.0355 0.624164061823001 0.805114376993706 GO:0032451 demethylase activity 1/450 40/18639 0.025 1.0355 0.624164061823001 0.805114376993706 GO:0061791 GTPase motor activity 1/450 40/18639 0.025 1.0355 0.624164061823001 0.805114376993706 GO:1990606 membrane scission GTPase motor activity 1/450 40/18639 0.025 1.0355 0.624164061823001 0.805114376993706 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 6/450 268/18639 0.0223880597014925 0.927313432835821 0.630812092613775 0.806485364190146 GO:0004197 cysteine-type endopeptidase activity 2/450 88/18639 0.0227272727272727 0.941363636363636 0.630820560242523 0.806485364190146 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/450 41/18639 0.024390243902439 1.01024390243902 0.633257355665662 0.806485364190146 GO:0042169 SH2 domain binding 1/450 41/18639 0.024390243902439 1.01024390243902 0.633257355665662 0.806485364190146 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/450 41/18639 0.024390243902439 1.01024390243902 0.633257355665662 0.806485364190146 GO:0140318 protein transporter activity 1/450 41/18639 0.024390243902439 1.01024390243902 0.633257355665662 0.806485364190146 GO:0140828 metal cation:monoatomic cation antiporter activity 1/450 41/18639 0.024390243902439 1.01024390243902 0.633257355665662 0.806485364190146 GO:0015297 antiporter activity 3/450 135/18639 0.0222222222222222 0.920444444444444 0.636400537640141 0.807200907205578 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/450 181/18639 0.0220994475138122 0.9153591160221 0.639391569961029 0.807200907205578 GO:0061134 peptidase regulator activity 5/450 226/18639 0.0221238938053097 0.916371681415929 0.639834395947052 0.807200907205578 GO:0016779 nucleotidyltransferase activity 3/450 136/18639 0.0220588235294118 0.913676470588235 0.641350024625891 0.807200907205578 GO:0008307 structural constituent of muscle 1/450 42/18639 0.0238095238095238 0.986190476190476 0.642131115744727 0.807200907205578 GO:0019894 kinesin binding 1/450 42/18639 0.0238095238095238 0.986190476190476 0.642131115744727 0.807200907205578 GO:0051879 Hsp90 protein binding 1/450 42/18639 0.0238095238095238 0.986190476190476 0.642131115744727 0.807200907205578 GO:0019210 kinase inhibitor activity 2/450 90/18639 0.0222222222222222 0.920444444444444 0.643004990092637 0.807200907205578 GO:0072341 modified amino acid binding 2/450 91/18639 0.021978021978022 0.91032967032967 0.648977342040131 0.809744802331897 GO:0005245 voltage-gated calcium channel activity 1/450 43/18639 0.0232558139534884 0.963255813953488 0.650790630608139 0.809744802331897 GO:0008200 ion channel inhibitor activity 1/450 43/18639 0.0232558139534884 0.963255813953488 0.650790630608139 0.809744802331897 GO:0008375 acetylglucosaminyltransferase activity 1/450 43/18639 0.0232558139534884 0.963255813953488 0.650790630608139 0.809744802331897 GO:0048156 tau protein binding 1/450 43/18639 0.0232558139534884 0.963255813953488 0.650790630608139 0.809744802331897 GO:0140767 enzyme-substrate adaptor activity 3/450 139/18639 0.0215827338129496 0.893956834532374 0.655913289380799 0.8146767534182 GO:0001046 core promoter sequence-specific DNA binding 1/450 44/18639 0.0227272727272727 0.941363636363636 0.659241061680754 0.81592687739713 GO:0016248 channel inhibitor activity 1/450 44/18639 0.0227272727272727 0.941363636363636 0.659241061680754 0.81592687739713 GO:0140303 intramembrane lipid transporter activity 1/450 45/18639 0.0222222222222222 0.920444444444444 0.667487446313379 0.823234517119834 GO:0141110 transporter inhibitor activity 1/450 45/18639 0.0222222222222222 0.920444444444444 0.667487446313379 0.823234517119834 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/450 46/18639 0.0217391304347826 0.900434782608696 0.675534700758844 0.830246319289278 GO:0030291 protein serine/threonine kinase inhibitor activity 1/450 46/18639 0.0217391304347826 0.900434782608696 0.675534700758844 0.830246319289278 GO:0043495 protein-membrane adaptor activity 1/450 47/18639 0.0212765957446809 0.881276595744681 0.683387623076841 0.834065102470519 GO:0099095 ligand-gated monoatomic anion channel activity 1/450 47/18639 0.0212765957446809 0.881276595744681 0.683387623076841 0.834065102470519 GO:0140359 ABC-type transporter activity 1/450 47/18639 0.0212765957446809 0.881276595744681 0.683387623076841 0.834065102470519 GO:0140938 histone H3 methyltransferase activity 1/450 47/18639 0.0212765957446809 0.881276595744681 0.683387623076841 0.834065102470519 GO:0032266 phosphatidylinositol-3-phosphate binding 1/450 48/18639 0.0208333333333333 0.862916666666667 0.691050895969237 0.839047979043823 GO:0038187 pattern recognition receptor activity 1/450 48/18639 0.0208333333333333 0.862916666666667 0.691050895969237 0.839047979043823 GO:0140693 molecular condensate scaffold activity 1/450 48/18639 0.0208333333333333 0.862916666666667 0.691050895969237 0.839047979043823 GO:0060590 ATPase regulator activity 1/450 49/18639 0.0204081632653061 0.84530612244898 0.698529089547519 0.846665430951561 GO:0019842 vitamin binding 3/450 150/18639 0.02 0.8284 0.705644958133992 0.849650932903937 GO:0015605 organophosphate ester transmembrane transporter activity 1/450 50/18639 0.02 0.8284 0.705826664033996 0.849650932903937 GO:0032813 tumor necrosis factor receptor superfamily binding 1/450 50/18639 0.02 0.8284 0.705826664033996 0.849650932903937 GO:0048020 CCR chemokine receptor binding 1/450 50/18639 0.02 0.8284 0.705826664033996 0.849650932903937 GO:0005272 sodium channel activity 1/450 51/18639 0.0196078431372549 0.812156862745098 0.712947972398335 0.853277078313345 GO:0016597 amino acid binding 1/450 51/18639 0.0196078431372549 0.812156862745098 0.712947972398335 0.853277078313345 GO:0030544 Hsp70 protein binding 1/450 51/18639 0.0196078431372549 0.812156862745098 0.712947972398335 0.853277078313345 GO:0004722 protein serine/threonine phosphatase activity 2/450 103/18639 0.0194174757281553 0.804271844660194 0.714563520536095 0.853277078313345 GO:0016829 lyase activity 4/450 200/18639 0.02 0.8284 0.71490782237064 0.853277078313345 GO:0017046 peptide hormone binding 1/450 53/18639 0.0188679245283019 0.781509433962264 0.726678681754944 0.864391054608672 GO:0140296 general transcription initiation factor binding 1/450 53/18639 0.0188679245283019 0.781509433962264 0.726678681754944 0.864391054608672 GO:0140375 immune receptor activity 3/450 156/18639 0.0192307692307692 0.796538461538462 0.730364265772891 0.867307565605308 GO:0015485 cholesterol binding 1/450 54/18639 0.0185185185185185 0.767037037037037 0.733296275277502 0.867857376296438 GO:0051287 NAD binding 1/450 54/18639 0.0185185185185185 0.767037037037037 0.733296275277502 0.867857376296438 GO:0008374 O-acyltransferase activity 1/450 55/18639 0.0181818181818182 0.753090909090909 0.739753992583132 0.871760697571645 GO:0140313 molecular sequestering activity 1/450 55/18639 0.0181818181818182 0.753090909090909 0.739753992583132 0.871760697571645 GO:0031625 ubiquitin protein ligase binding 6/450 302/18639 0.0198675496688742 0.822913907284768 0.740382406684528 0.871760697571645 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 7/450 349/18639 0.0200573065902579 0.830773638968481 0.741554618986975 0.871760697571645 GO:0004222 metalloendopeptidase activity 2/450 110/18639 0.0181818181818182 0.753090909090909 0.747864638813212 0.877710920009496 GO:0008408 3'-5' exonuclease activity 1/450 58/18639 0.0172413793103448 0.714137931034483 0.758205966860126 0.888364657837781 GO:0036002 pre-mRNA binding 1/450 59/18639 0.0169491525423729 0.702033898305085 0.764061804270004 0.893736187024647 GO:0017124 SH3 domain binding 2/450 115/18639 0.0173913043478261 0.720347826086956 0.769562625882024 0.894467140489184 GO:0001098 basal transcription machinery binding 1/450 60/18639 0.0166666666666667 0.690333333333333 0.769776130861957 0.894467140489184 GO:0001099 basal RNA polymerase II transcription machinery binding 1/450 60/18639 0.0166666666666667 0.690333333333333 0.769776130861957 0.894467140489184 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/450 60/18639 0.0166666666666667 0.690333333333333 0.769776130861957 0.894467140489184 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/450 167/18639 0.0179640718562874 0.744071856287425 0.771410921469969 0.894887587117803 GO:0004857 enzyme inhibitor activity 8/450 416/18639 0.0192307692307692 0.796538461538462 0.790011480976572 0.914955636122785 GO:0044389 ubiquitin-like protein ligase binding 6/450 322/18639 0.0186335403726708 0.771801242236025 0.792935176664447 0.915738462213143 GO:0019843 rRNA binding 1/450 65/18639 0.0153846153846154 0.637230769230769 0.796341699027433 0.915738462213143 GO:0038024 cargo receptor activity 1/450 65/18639 0.0153846153846154 0.637230769230769 0.796341699027433 0.915738462213143 GO:0005126 cytokine receptor binding 5/450 275/18639 0.0181818181818182 0.753090909090909 0.796963253139795 0.915738462213143 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/450 122/18639 0.0163934426229508 0.679016393442623 0.79720048204046 0.915738462213143 GO:0008173 RNA methyltransferase activity 1/450 67/18639 0.0149253731343284 0.618208955223881 0.806090645638789 0.921433697372469 GO:0042054 histone methyltransferase activity 1/450 67/18639 0.0149253731343284 0.618208955223881 0.806090645638789 0.921433697372469 GO:0050840 extracellular matrix binding 1/450 67/18639 0.0149253731343284 0.618208955223881 0.806090645638789 0.921433697372469 GO:0030145 manganese ion binding 1/450 68/18639 0.0147058823529412 0.609117647058824 0.81078907388898 0.923800192777881 GO:0032934 sterol binding 1/450 68/18639 0.0147058823529412 0.609117647058824 0.81078907388898 0.923800192777881 GO:0016279 protein-lysine N-methyltransferase activity 1/450 69/18639 0.0144927536231884 0.600289855072464 0.815373905979333 0.927520802432802 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/450 128/18639 0.015625 0.6471875 0.818515190390826 0.928104768653656 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/450 70/18639 0.0142857142857143 0.591714285714286 0.81984788240956 0.928104768653656 GO:0016278 lysine N-methyltransferase activity 1/450 70/18639 0.0142857142857143 0.591714285714286 0.81984788240956 0.928104768653656 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/450 130/18639 0.0153846153846154 0.637230769230769 0.825162044646865 0.931867444993591 GO:0005262 calcium channel activity 2/450 131/18639 0.0152671755725191 0.63236641221374 0.828402850733776 0.931867444993591 GO:0005518 collagen binding 1/450 72/18639 0.0138888888888889 0.575277777777778 0.828473902021329 0.931867444993591 GO:0042379 chemokine receptor binding 1/450 72/18639 0.0138888888888889 0.575277777777778 0.828473902021329 0.931867444993591 GO:0008234 cysteine-type peptidase activity 3/450 187/18639 0.0160427807486631 0.664491978609626 0.832885823595665 0.9338416810012 GO:0031406 carboxylic acid binding 3/450 187/18639 0.0160427807486631 0.664491978609626 0.832885823595665 0.9338416810012 GO:0043177 organic acid binding 3/450 189/18639 0.0158730158730159 0.657460317460317 0.838176001249547 0.938276638341452 GO:0019003 GDP binding 1/450 75/18639 0.0133333333333333 0.552266666666667 0.840646316905548 0.939545883600318 GO:0003724 RNA helicase activity 1/450 77/18639 0.012987012987013 0.537922077922078 0.848278498591036 0.946571086523013 GO:0008236 serine-type peptidase activity 3/450 194/18639 0.0154639175257732 0.640515463917526 0.850773639631965 0.94785082196715 GO:0008186 ATP-dependent activity, acting on RNA 1/450 79/18639 0.0126582278481013 0.524303797468354 0.855545913322789 0.950156045917726 GO:0046332 SMAD binding 1/450 79/18639 0.0126582278481013 0.524303797468354 0.855545913322789 0.950156045917726 GO:0000049 tRNA binding 1/450 80/18639 0.0125 0.51775 0.859048302277786 0.950334746315423 GO:0048306 calcium-dependent protein binding 1/450 80/18639 0.0125 0.51775 0.859048302277786 0.950334746315423 GO:0017171 serine hydrolase activity 3/450 198/18639 0.0151515151515152 0.627575757575758 0.860229347789493 0.950334746315423 GO:0004175 endopeptidase activity 7/450 405/18639 0.0172839506172839 0.715901234567901 0.861205530258918 0.950334746315423 GO:0015101 organic cation transmembrane transporter activity 1/450 81/18639 0.0123456790123457 0.511358024691358 0.862465957538036 0.950334746315423 GO:0001540 amyloid-beta binding 1/450 83/18639 0.0120481927710843 0.499036144578313 0.869055199768019 0.954602820995183 GO:0008135 translation factor activity, RNA binding 1/450 83/18639 0.0120481927710843 0.499036144578313 0.869055199768019 0.954602820995183 GO:0004527 exonuclease activity 1/450 84/18639 0.0119047619047619 0.493095238095238 0.872230731138163 0.954930569977323 GO:0180051 translation factor activity 1/450 84/18639 0.0119047619047619 0.493095238095238 0.872230731138163 0.954930569977323 GO:0008168 methyltransferase activity 3/450 204/18639 0.0147058823529412 0.609117647058824 0.873428672112971 0.954930569977323 GO:0016209 antioxidant activity 1/450 86/18639 0.0116279069767442 0.481627906976744 0.878353121637218 0.957336813195293 GO:0050660 flavin adenine dinucleotide binding 1/450 86/18639 0.0116279069767442 0.481627906976744 0.878353121637218 0.957336813195293 GO:0003730 mRNA 3'-UTR binding 4/450 262/18639 0.0152671755725191 0.63236641221374 0.880363138011929 0.958042238424746 GO:0003727 single-stranded RNA binding 1/450 89/18639 0.0112359550561798 0.465393258426966 0.886992193962772 0.963764315851358 GO:0016741 transferase activity, transferring one-carbon groups 3/450 215/18639 0.013953488372093 0.577953488372093 0.894789031780068 0.969489000500489 GO:0043178 alcohol binding 1/450 92/18639 0.0108695652173913 0.450217391304348 0.895019006151945 0.969489000500489 GO:0051219 phosphoprotein binding 1/450 93/18639 0.010752688172043 0.445376344086022 0.897566126830848 0.970752287941671 GO:0008276 protein methyltransferase activity 1/450 95/18639 0.0105263157894737 0.436 0.90247685995466 0.97456410529666 GO:0016407 acetyltransferase activity 1/450 96/18639 0.0104166666666667 0.431458333333333 0.904843415876813 0.975621045032821 GO:0030246 carbohydrate binding 4/450 280/18639 0.0142857142857143 0.591714285714286 0.90922138972321 0.978840179135401 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/450 229/18639 0.0131004366812227 0.542620087336245 0.917274105762549 0.985999535705003 GO:0019001 guanyl nucleotide binding 6/450 400/18639 0.015 0.6213 0.923515635447079 0.988627048228248 GO:0032561 guanyl ribonucleotide binding 6/450 400/18639 0.015 0.6213 0.923515635447079 0.988627048228248 GO:0140030 modification-dependent protein binding 2/450 173/18639 0.0115606936416185 0.478843930635838 0.923937369396812 0.988627048228248 GO:0004252 serine-type endopeptidase activity 2/450 176/18639 0.0113636363636364 0.470681818181818 0.928359567206608 0.990008700313916 GO:0004843 cysteine-type deubiquitinase activity 1/450 108/18639 0.00925925925925926 0.383518518518518 0.929145506128702 0.990008700313916 GO:0043021 ribonucleoprotein complex binding 2/450 177/18639 0.0112994350282486 0.468022598870056 0.929778947073188 0.990008700313916 GO:0061630 ubiquitin protein ligase activity 5/450 353/18639 0.0141643059490085 0.586685552407932 0.930861665586769 0.990008700313916 GO:0043022 ribosome binding 1/450 112/18639 0.00892857142857143 0.369821428571429 0.935781780457628 0.993738053869656 GO:0033218 amide binding 3/450 247/18639 0.0121457489878543 0.503076923076923 0.939741361770082 0.995579970954942 GO:0101005 deubiquitinase activity 1/450 115/18639 0.00869565217391304 0.360173913043478 0.940348649664412 0.995579970954942 GO:0019208 phosphatase regulator activity 1/450 117/18639 0.00854700854700855 0.354017094017094 0.94321172107332 0.997109533706081 GO:0061659 ubiquitin-like protein ligase activity 5/450 372/18639 0.0134408602150538 0.556720430107527 0.94810819913802 0.997634878298367 GO:0003697 single-stranded DNA binding 1/450 121/18639 0.00826446280991736 0.342314049586777 0.948533035391202 0.997634878298367 GO:0008528 G protein-coupled peptide receptor activity 1/450 122/18639 0.00819672131147541 0.339508196721311 0.949783717650299 0.997634878298367 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/450 122/18639 0.00819672131147541 0.339508196721311 0.949783717650299 0.997634878298367 GO:0005525 GTP binding 5/450 378/18639 0.0132275132275132 0.547883597883598 0.952685101167337 0.997634878298367 GO:0019783 ubiquitin-like protein peptidase activity 1/450 127/18639 0.0078740157480315 0.326141732283465 0.955596643024437 0.997634878298367 GO:0042826 histone deacetylase binding 1/450 127/18639 0.0078740157480315 0.326141732283465 0.955596643024437 0.997634878298367 GO:0001653 peptide receptor activity 1/450 128/18639 0.0078125 0.32359375 0.956676024541237 0.997634878298367 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/450 130/18639 0.00769230769230769 0.318615384615385 0.958756877303061 0.997634878298367 GO:0031072 heat shock protein binding 1/450 131/18639 0.00763358778625954 0.31618320610687 0.959759600584364 0.997634878298367 GO:0005179 hormone activity 1/450 132/18639 0.00757575757575758 0.313787878787879 0.960737998019907 0.997634878298367 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/450 132/18639 0.00757575757575758 0.313787878787879 0.960737998019907 0.997634878298367 GO:0051087 protein-folding chaperone binding 1/450 134/18639 0.00746268656716418 0.30910447761194 0.962624156558788 0.998119147582342 GO:0000510 H3-H4 histone complex chaperone activity 1/450 151/18639 0.00662251655629139 0.274304635761589 0.975410241752291 0.999847035581694 GO:0140584 chromatin extrusion motor activity 1/450 151/18639 0.00662251655629139 0.274304635761589 0.975410241752291 0.999847035581694 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/450 151/18639 0.00662251655629139 0.274304635761589 0.975410241752291 0.999847035581694 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/450 151/18639 0.00662251655629139 0.274304635761589 0.975410241752291 0.999847035581694 GO:0015616 DNA translocase activity 1/450 152/18639 0.00657894736842105 0.2725 0.976008759234521 0.999847035581694 GO:0140674 ATP-dependent histone chaperone activity 1/450 152/18639 0.00657894736842105 0.2725 0.976008759234521 0.999847035581694 GO:0061775 cohesin loader activity 1/450 153/18639 0.0065359477124183 0.270718954248366 0.976592740320931 0.999847035581694 GO:0004386 helicase activity 1/450 155/18639 0.00645161290322581 0.267225806451613 0.977718493919851 0.999847035581694 GO:0140658 ATP-dependent chromatin remodeler activity 1/450 158/18639 0.00632911392405063 0.262151898734177 0.979306635847116 0.999847035581694 GO:0003689 DNA clamp loader activity 1/450 160/18639 0.00625 0.258875 0.980302132738517 0.999847035581694 GO:0140713 histone chaperone activity 1/450 164/18639 0.00609756097560976 0.252560975609756 0.982152048402425 0.999847035581694 GO:0042393 histone binding 2/450 247/18639 0.00809716599190283 0.335384615384615 0.983490593376076 0.999847035581694 GO:0042277 peptide binding 2/450 249/18639 0.00803212851405622 0.332690763052209 0.984177552537807 0.999847035581694 GO:0004842 ubiquitin-protein transferase activity 5/450 449/18639 0.0111358574610245 0.461247216035635 0.984990072362201 0.999847035581694 GO:0140597 protein carrier chaperone 1/450 188/18639 0.00531914893617021 0.22031914893617 0.990127978381049 0.999847035581694 GO:0019787 ubiquitin-like protein transferase activity 5/450 479/18639 0.0104384133611691 0.432359081419624 0.991005802996512 0.999847035581694 GO:0016755 aminoacyltransferase activity 5/450 496/18639 0.0100806451612903 0.417540322580645 0.993313019870099 0.999847035581694 GO:0004518 nuclease activity 1/450 209/18639 0.00478468899521531 0.198181818181818 0.994123839859636 0.999847035581694 GO:0008094 ATP-dependent activity, acting on DNA 1/450 210/18639 0.00476190476190476 0.197238095238095 0.99426731636876 0.999847035581694 GO:0005125 cytokine activity 1/450 234/18639 0.00427350427350427 0.177008547008547 0.99683389482367 0.999847035581694 GO:0140097 catalytic activity, acting on DNA 2/450 336/18639 0.00595238095238095 0.246547619047619 0.997616497823832 0.999847035581694 GO:0140104 molecular carrier activity 1/450 249/18639 0.00401606425702811 0.166345381526104 0.997816229354962 0.999847035581694 GO:0046982 protein heterodimerization activity 2/450 369/18639 0.00542005420054201 0.22449864498645 0.998858633383886 0.999847035581694 GO:0140098 catalytic activity, acting on RNA 2/450 387/18639 0.00516795865633075 0.21405684754522 0.999238800401151 0.999847035581694 GO:0045182 translation regulator activity 1/450 356/18639 0.00280898876404494 0.116348314606742 0.999847035581694 0.999847035581694