ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003779 actin binding 17/256 443/18639 0.0383747178329571 2.79400924097065 0.000142809286616347 0.0321742285949949 GO:0023023 MHC protein complex binding 5/256 37/18639 0.135135135135135 9.83899915540541 0.000143040510051805 0.0321742285949949 GO:0003735 structural constituent of ribosome 10/256 175/18639 0.0571428571428571 4.16049107142857 0.00015771680683821 0.0321742285949949 GO:0042169 SH2 domain binding 5/256 41/18639 0.121951219512195 8.87909679878049 0.000235163788879904 0.0359800596986253 GO:0023026 MHC class II protein complex binding 4/256 27/18639 0.148148148148148 10.7864583333333 0.000475678917705762 0.0578255025944632 GO:0044325 transmembrane transporter binding 8/256 136/18639 0.0588235294117647 4.28285845588235 0.000589030814312328 0.0578255025944632 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/256 13/18639 0.230769230769231 16.8019831730769 0.00066140280745301 0.0578255025944632 GO:0004601 peroxidase activity 5/256 57/18639 0.087719298245614 6.38671875 0.00109938142085433 0.0786792931016479 GO:0016209 antioxidant activity 6/256 86/18639 0.0697674418604651 5.07966933139535 0.0011894815577868 0.0786792931016479 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 5/256 59/18639 0.0847457627118644 6.17021980932203 0.00128560936440601 0.0786792931016479 GO:0030246 carbohydrate binding 11/256 280/18639 0.0392857142857143 2.86033761160714 0.00176488322236837 0.0943326914170206 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/256 39/18639 0.102564102564103 7.46754807692308 0.0019596798033214 0.0943326914170206 GO:0140662 ATP-dependent protein folding chaperone 4/256 40/18639 0.1 7.280859375 0.00215422143497643 0.0943326914170206 GO:0001614 purinergic nucleotide receptor activity 3/256 20/18639 0.15 10.9212890625 0.00245560340095677 0.0943326914170206 GO:0016502 nucleotide receptor activity 3/256 20/18639 0.15 10.9212890625 0.00245560340095677 0.0943326914170206 GO:0051015 actin filament binding 9/256 209/18639 0.0430622009569378 3.13529829545455 0.00246621415469335 0.0943326914170206 GO:0033691 sialic acid binding 3/256 22/18639 0.136363636363636 9.92844460227273 0.00325078021551269 0.117028087758457 GO:0019955 cytokine binding 7/256 144/18639 0.0486111111111111 3.539306640625 0.00379251314238677 0.117132771947032 GO:0008237 metallopeptidase activity 8/256 184/18639 0.0434782608695652 3.1655910326087 0.00399220902343431 0.117132771947032 GO:0004222 metalloendopeptidase activity 6/256 110/18639 0.0545454545454545 3.97137784090909 0.00412880124136237 0.117132771947032 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/256 24/18639 0.125 9.10107421875 0.00418699985252254 0.117132771947032 GO:0038187 pattern recognition receptor activity 4/256 48/18639 0.0833333333333333 6.0673828125 0.00421065520071032 0.117132771947032 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/256 25/18639 0.12 8.73703125 0.00471018084499159 0.125331768571081 GO:0005021 vascular endothelial growth factor receptor activity 4/256 51/18639 0.0784313725490196 5.71047794117647 0.00523752696047924 0.133556937492221 GO:0140375 immune receptor activity 7/256 156/18639 0.0448717948717949 3.26705228365385 0.00585470497039614 0.138183889417071 GO:0004364 glutathione transferase activity 3/256 27/18639 0.111111111111111 8.08984375 0.00587055739353569 0.138183889417071 GO:0050698 proteoglycan sulfotransferase activity 3/256 28/18639 0.107142857142857 7.80092075892857 0.00650914265425627 0.147540566829809 GO:0005178 integrin binding 7/256 161/18639 0.0434782608695652 3.1655910326087 0.0069250250773343 0.148951964055629 GO:0003785 actin monomer binding 3/256 29/18639 0.103448275862069 7.53192349137931 0.0071875010900379 0.148951964055629 GO:0016651 oxidoreductase activity, acting on NAD(P)H 5/256 88/18639 0.0568181818181818 4.13685191761364 0.007301566865472 0.148951964055629 GO:0071723 lipopeptide binding 2/256 10/18639 0.2 14.56171875 0.00786290003327812 0.155228865173104 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/256 60/18639 0.0666666666666667 4.85390625 0.00928754150933481 0.171426100657762 GO:0042608 T cell receptor binding 2/256 11/18639 0.181818181818182 13.2379261363636 0.00952367225876457 0.171426100657762 GO:1990948 ubiquitin ligase inhibitor activity 2/256 11/18639 0.181818181818182 13.2379261363636 0.00952367225876457 0.171426100657762 GO:0019956 chemokine binding 3/256 33/18639 0.0909090909090909 6.61896306818182 0.0103093761129913 0.17738405361916 GO:0004896 cytokine receptor activity 5/256 96/18639 0.0520833333333333 3.7921142578125 0.0104343560952447 0.17738405361916 GO:0019838 growth factor binding 6/256 136/18639 0.0441176470588235 3.21214384191176 0.0113062060041855 0.182401960178525 GO:0015132 prostaglandin transmembrane transporter activity 2/256 12/18639 0.166666666666667 12.134765625 0.0113256119065097 0.182401960178525 GO:0008253 5'-nucleotidase activity 2/256 13/18639 0.153846153846154 11.2013221153846 0.0132645590154291 0.197997807742503 GO:0017154 semaphorin receptor activity 2/256 13/18639 0.153846153846154 11.2013221153846 0.0132645590154291 0.197997807742503 GO:0071714 icosanoid transmembrane transporter activity 2/256 13/18639 0.153846153846154 11.2013221153846 0.0132645590154291 0.197997807742503 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/256 68/18639 0.0588235294117647 4.28285845588235 0.0142512455460014 0.207661006527448 GO:0097110 scaffold protein binding 4/256 70/18639 0.0571428571428571 4.16049107142857 0.0157097762174061 0.219036904585814 GO:0005518 collagen binding 4/256 72/18639 0.0555555555555556 4.044921875 0.0172589265500693 0.219036904585814 GO:0008252 nucleotidase activity 2/256 15/18639 0.133333333333333 9.7078125 0.0175372685044197 0.219036904585814 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/256 15/18639 0.133333333333333 9.7078125 0.0175372685044197 0.219036904585814 GO:0016846 carbon-sulfur lyase activity 2/256 15/18639 0.133333333333333 9.7078125 0.0175372685044197 0.219036904585814 GO:0034483 heparan sulfate sulfotransferase activity 2/256 15/18639 0.133333333333333 9.7078125 0.0175372685044197 0.219036904585814 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/256 15/18639 0.133333333333333 9.7078125 0.0175372685044197 0.219036904585814 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/256 41/18639 0.0731707317073171 5.32745807926829 0.018593514524405 0.225115574915107 GO:0005200 structural constituent of cytoskeleton 5/256 112/18639 0.0446428571428571 3.25038364955357 0.0192267867021561 0.225115574915107 GO:0044183 protein folding chaperone 4/256 75/18639 0.0533333333333333 3.883125 0.0197558942763282 0.225115574915107 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/256 16/18639 0.125 9.10107421875 0.0198631389630977 0.225115574915107 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/256 16/18639 0.125 9.10107421875 0.0198631389630977 0.225115574915107 GO:0048156 tau protein binding 3/256 43/18639 0.0697674418604651 5.07966933139535 0.0211007354655691 0.233024576200053 GO:0009055 electron transfer activity 5/256 116/18639 0.0431034482758621 3.13830145474138 0.0220072313983005 0.233024576200053 GO:0016805 dipeptidase activity 2/256 17/18639 0.117647058823529 8.56571691176471 0.0223102299483928 0.233024576200053 GO:0003954 NADH dehydrogenase activity 3/256 44/18639 0.0681818181818182 4.96422230113636 0.0224203631362508 0.233024576200053 GO:0019199 transmembrane receptor protein kinase activity 4/256 78/18639 0.0512820512820513 3.73377403846154 0.0224647875748418 0.233024576200053 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/256 18/18639 0.111111111111111 8.08984375 0.0248748002238208 0.238986950426734 GO:0051082 unfolded protein binding 5/256 121/18639 0.0413223140495868 3.00861957644628 0.0258338096904133 0.238986950426734 GO:0140996 histone H3 kinase activity 10/256 357/18639 0.0280112044817927 2.03945640756303 0.0262216443621489 0.238986950426734 GO:0030506 ankyrin binding 2/256 19/18639 0.105263157894737 7.6640625 0.0275531877511166 0.238986950426734 GO:0035173 histone kinase activity 10/256 360/18639 0.0277777777777778 2.0224609375 0.0275588417274927 0.238986950426734 GO:0032266 phosphatidylinositol-3-phosphate binding 3/256 48/18639 0.0625 4.550537109375 0.0281388222677664 0.238986950426734 GO:0005004 GPI-linked ephrin receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0005008 hepatocyte growth factor receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0005009 insulin receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0005011 macrophage colony-stimulating factor receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0005020 stem cell factor receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0008288 boss receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0016763 pentosyltransferase activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0036332 placental growth factor receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0038062 protein tyrosine kinase collagen receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0060175 brain-derived neurotrophic factor receptor activity 3/256 49/18639 0.0612244897959184 4.45766900510204 0.0296781180268493 0.238986950426734 GO:0005006 epidermal growth factor receptor activity 3/256 50/18639 0.06 4.368515625 0.0312610752909707 0.239147225975926 GO:0005007 fibroblast growth factor receptor activity 3/256 50/18639 0.06 4.368515625 0.0312610752909707 0.239147225975926 GO:0005017 platelet-derived growth factor receptor activity 3/256 50/18639 0.06 4.368515625 0.0312610752909707 0.239147225975926 GO:0005019 platelet-derived growth factor beta-receptor activity 3/256 50/18639 0.06 4.368515625 0.0312610752909707 0.239147225975926 GO:0005010 insulin-like growth factor receptor activity 3/256 51/18639 0.0588235294117647 4.28285845588235 0.0328875470616264 0.242156405452424 GO:0005030 neurotrophin receptor activity 3/256 51/18639 0.0588235294117647 4.28285845588235 0.0328875470616264 0.242156405452424 GO:0015125 bile acid transmembrane transporter activity 2/256 21/18639 0.0952380952380952 6.93415178571429 0.0332371536895485 0.242156405452424 GO:0070182 DNA polymerase binding 2/256 21/18639 0.0952380952380952 6.93415178571429 0.0332371536895485 0.242156405452424 GO:0016798 hydrolase activity, acting on glycosyl bonds 5/256 130/18639 0.0384615384615385 2.80033052884615 0.0337412482858954 0.242936987658447 GO:0061133 endopeptidase activator activity 2/256 22/18639 0.0909090909090909 6.61896306818182 0.036235791036952 0.246638281952705 GO:0005003 ephrin receptor activity 3/256 53/18639 0.0566037735849057 4.12124115566038 0.0362703355812801 0.246638281952705 GO:0005005 transmembrane-ephrin receptor activity 3/256 53/18639 0.0566037735849057 4.12124115566038 0.0362703355812801 0.246638281952705 GO:0008146 sulfotransferase activity 3/256 53/18639 0.0566037735849057 4.12124115566038 0.0362703355812801 0.246638281952705 GO:0038064 collagen receptor activity 3/256 53/18639 0.0566037735849057 4.12124115566038 0.0362703355812801 0.246638281952705 GO:0072341 modified amino acid binding 4/256 91/18639 0.043956043956044 3.20037774725275 0.0367328313702076 0.247038382401836 GO:0004602 glutathione peroxidase activity 2/256 23/18639 0.0869565217391304 6.33118206521739 0.0393343607196235 0.258845470542039 GO:0016493 C-C chemokine receptor activity 2/256 23/18639 0.0869565217391304 6.33118206521739 0.0393343607196235 0.258845470542039 GO:0170055 lipid transmembrane transporter activity 3/256 56/18639 0.0535714285714286 3.90046037946429 0.0416659671285158 0.269131212869011 GO:0045296 cadherin binding 9/256 334/18639 0.0269461077844311 1.96190821482036 0.0417769039584249 0.269131212869011 GO:0019957 C-C chemokine binding 2/256 24/18639 0.0833333333333333 6.0673828125 0.0425295753439053 0.269956013832209 GO:0015078 proton transmembrane transporter activity 6/256 185/18639 0.0324324324324324 2.3613597972973 0.0427871459832096 0.269956013832209 GO:0004713 protein tyrosine kinase activity 5/256 140/18639 0.0357142857142857 2.60030691964286 0.044120291906189 0.275526720883547 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 3/256 58/18639 0.0517241379310345 3.76596174568966 0.0454744443370436 0.280407496264123 GO:0005537 D-mannose binding 2/256 25/18639 0.08 5.8246875 0.0458182183438109 0.280407496264123 GO:0001637 G protein-coupled chemoattractant receptor activity 2/256 26/18639 0.0769230769230769 5.60066105769231 0.0491971426681471 0.289506262624096 GO:0004435 phosphatidylinositol phospholipase C activity 2/256 26/18639 0.0769230769230769 5.60066105769231 0.0491971426681471 0.289506262624096 GO:0004950 chemokine receptor activity 2/256 26/18639 0.0769230769230769 5.60066105769231 0.0491971426681471 0.289506262624096 GO:0030507 spectrin binding 2/256 26/18639 0.0769230769230769 5.60066105769231 0.0491971426681471 0.289506262624096 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/256 61/18639 0.0491803278688525 3.58075051229508 0.051498380251211 0.300161987749915 GO:0015252 proton channel activity 2/256 27/18639 0.0740740740740741 5.39322916666667 0.052663269490116 0.304055857810859 GO:0005507 copper ion binding 3/256 63/18639 0.0476190476190476 3.46707589285714 0.0557179373777574 0.316546956696547 GO:0097718 disordered domain specific binding 2/256 28/18639 0.0714285714285714 5.20061383928571 0.0562135869390283 0.316546956696547 GO:0141003 histone H2AX kinase activity 9/256 354/18639 0.0254237288135593 1.85106594279661 0.0563784612417053 0.316546956696547 GO:0004629 phospholipase C activity 2/256 29/18639 0.0689655172413793 5.02128232758621 0.0598451488537683 0.332956646350057 GO:0016500 protein-hormone receptor activity 3/256 67/18639 0.0447761194029851 3.26008628731343 0.0646323486181895 0.356351327516504 GO:0051020 GTPase binding 8/256 315/18639 0.0253968253968254 1.84910714285714 0.0699177478556491 0.382050550782654 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/256 70/18639 0.0428571428571429 3.12036830357143 0.0717212276680114 0.385029748533535 GO:0016782 transferase activity, transferring sulphur-containing groups 3/256 70/18639 0.0428571428571429 3.12036830357143 0.0717212276680114 0.385029748533535 GO:0035401 histone H3Y41 kinase activity 4/256 115/18639 0.0347826086956522 2.53247282608696 0.0740812016400621 0.390842201756189 GO:0140801 histone H2AXY142 kinase activity 4/256 115/18639 0.0347826086956522 2.53247282608696 0.0740812016400621 0.390842201756189 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/256 33/18639 0.0606060606060606 4.41264204545455 0.0751271497626693 0.392972783373963 GO:0042379 chemokine receptor binding 3/256 72/18639 0.0416666666666667 3.03369140625 0.0766325539574548 0.397450195101376 GO:1990782 protein tyrosine kinase binding 4/256 117/18639 0.0341880341880342 2.48918269230769 0.077824172200399 0.399960158361773 GO:0015035 protein-disulfide reductase activity 2/256 34/18639 0.0588235294117647 4.28285845588235 0.0791229568343764 0.399960158361773 GO:0015399 primary active transmembrane transporter activity 5/256 166/18639 0.0301204819277108 2.19302993222892 0.0791639699225691 0.399960158361773 GO:0022853 active monoatomic ion transmembrane transporter activity 4/256 118/18639 0.0338983050847458 2.46808792372881 0.0797306198041444 0.399960158361773 GO:0055106 ubiquitin-protein transferase regulator activity 2/256 36/18639 0.0555555555555556 4.044921875 0.0873066923750423 0.432279626972807 GO:0008528 G protein-coupled peptide receptor activity 4/256 122/18639 0.0327868852459016 2.38716700819672 0.0875860682101767 0.432279626972807 GO:0003823 antigen binding 5/256 174/18639 0.028735632183908 2.09220096982759 0.0922613088676717 0.451711368216121 GO:0035091 phosphatidylinositol binding 7/256 284/18639 0.0246478873239437 1.79457801496479 0.0975402354878608 0.4653394495276 GO:0048306 calcium-dependent protein binding 3/256 80/18639 0.0375 2.730322265625 0.0976794532443424 0.4653394495276 GO:0042826 histone deacetylase binding 4/256 127/18639 0.031496062992126 2.29318405511811 0.0979100821150488 0.4653394495276 GO:0000287 magnesium ion binding 6/256 230/18639 0.0260869565217391 1.89935461956522 0.0980862565180726 0.4653394495276 GO:0001653 peptide receptor activity 4/256 128/18639 0.03125 2.2752685546875 0.100040458512304 0.469323815777713 GO:0001618 virus receptor activity 3/256 81/18639 0.037037037037037 2.69661458333333 0.100459836383792 0.469323815777713 GO:0140272 exogenous protein binding 3/256 82/18639 0.0365853658536585 2.66372903963415 0.103271744573632 0.473162414154401 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/256 130/18639 0.0307692307692308 2.24026442307692 0.104365314139934 0.473162414154401 GO:0015036 disulfide oxidoreductase activity 2/256 40/18639 0.05 3.6404296875 0.104374061945824 0.473162414154401 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/256 40/18639 0.05 3.6404296875 0.104374061945824 0.473162414154401 GO:0017080 sodium channel regulator activity 2/256 41/18639 0.0487804878048781 3.5516387195122 0.108773064377691 0.479934242455754 GO:0048487 beta-tubulin binding 2/256 42/18639 0.0476190476190476 3.46707589285714 0.11322046103999 0.479934242455754 GO:0031406 carboxylic acid binding 5/256 187/18639 0.0267379679144385 1.94675384358289 0.11574861807756 0.479934242455754 GO:0043177 organic acid binding 5/256 189/18639 0.0264550264550265 1.92615327380952 0.119594239130638 0.479934242455754 GO:0019205 nucleobase-containing compound kinase activity 2/256 44/18639 0.0454545454545455 3.30948153409091 0.122251903478234 0.479934242455754 GO:0033218 amide binding 6/256 247/18639 0.0242914979757085 1.76862980769231 0.125738045522473 0.479934242455754 GO:0035403 histone H3T6 kinase activity 6/256 247/18639 0.0242914979757085 1.76862980769231 0.125738045522473 0.479934242455754 GO:0008009 chemokine activity 2/256 45/18639 0.0444444444444444 3.2359375 0.126831805005682 0.479934242455754 GO:0042605 peptide antigen binding 2/256 45/18639 0.0444444444444444 3.2359375 0.126831805005682 0.479934242455754 GO:0042578 phosphoric ester hydrolase activity 8/256 363/18639 0.0220385674931129 1.60459710743802 0.128354251383122 0.479934242455754 GO:0004090 carbonyl reductase (NADPH) activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0005381 iron ion transmembrane transporter activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0008519 ammonium channel activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0016427 tRNA (cytidine) methyltransferase activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0016868 intramolecular phosphotransferase activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0032395 MHC class II receptor activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0035256 G protein-coupled glutamate receptor binding 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0043295 glutathione binding 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0070097 delta-catenin binding 1/256 10/18639 0.1 7.280859375 0.129190452145383 0.479934242455754 GO:0004180 carboxypeptidase activity 2/256 46/18639 0.0434782608695652 3.1655910326087 0.131451810396721 0.479934242455754 GO:0001784 phosphotyrosine residue binding 2/256 47/18639 0.0425531914893617 3.09823803191489 0.13610996588875 0.479934242455754 GO:0051213 dioxygenase activity 3/256 93/18639 0.032258064516129 2.34866431451613 0.13613197659126 0.479934242455754 GO:0030695 GTPase regulator activity 10/256 489/18639 0.0204498977505112 1.48892829754601 0.137619376253108 0.479934242455754 GO:0060589 nucleoside-triphosphatase regulator activity 10/256 490/18639 0.0204081632653061 1.48588966836735 0.138896302673769 0.479934242455754 GO:0003953 NAD+ nucleosidase activity 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0005114 type II transforming growth factor beta receptor binding 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0005225 volume-sensitive anion channel activity 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0019206 nucleoside kinase activity 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0034511 U3 snoRNA binding 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0034713 type I transforming growth factor beta receptor binding 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0035252 UDP-xylosyltransferase activity 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0042285 xylosyltransferase activity 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0047676 arachidonate-CoA ligase activity 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0048407 platelet-derived growth factor binding 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0050786 RAGE receptor binding 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0140031 phosphorylation-dependent protein binding 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:1900750 oligopeptide binding 1/256 11/18639 0.0909090909090909 6.61896306818182 0.141157130134045 0.479934242455754 GO:0060590 ATPase regulator activity 2/256 49/18639 0.0408163265306122 2.97177933673469 0.145533139837941 0.482533593822701 GO:0005543 phospholipid binding 10/256 497/18639 0.0201207243460765 1.46496164486922 0.148008973091153 0.482533593822701 GO:0004725 protein tyrosine phosphatase activity 3/256 98/18639 0.0306122448979592 2.22883450255102 0.152115769970876 0.482533593822701 GO:0004000 adenosine deaminase activity 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0015368 calcium:monoatomic cation antiporter activity 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0017166 vinculin binding 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0035259 nuclear glucocorticoid receptor binding 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0035497 cAMP response element binding 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0042301 phosphate ion binding 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0045295 gamma-catenin binding 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0070679 inositol 1,4,5 trisphosphate binding 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0097371 MDM2/MDM4 family protein binding 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0097677 STAT family protein binding 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/256 12/18639 0.0833333333333333 6.0673828125 0.152959995427458 0.482533593822701 GO:0005542 folic acid binding 1/256 13/18639 0.0769230769230769 5.60066105769231 0.164601281795127 0.491112632050166 GO:0030955 potassium ion binding 1/256 13/18639 0.0769230769230769 5.60066105769231 0.164601281795127 0.491112632050166 GO:0032396 inhibitory MHC class I receptor activity 1/256 13/18639 0.0769230769230769 5.60066105769231 0.164601281795127 0.491112632050166 GO:0035325 Toll-like receptor binding 1/256 13/18639 0.0769230769230769 5.60066105769231 0.164601281795127 0.491112632050166 GO:0035673 oligopeptide transmembrane transporter activity 1/256 13/18639 0.0769230769230769 5.60066105769231 0.164601281795127 0.491112632050166 GO:0046974 histone H3K9 methyltransferase activity 1/256 13/18639 0.0769230769230769 5.60066105769231 0.164601281795127 0.491112632050166 GO:0070700 BMP receptor binding 1/256 13/18639 0.0769230769230769 5.60066105769231 0.164601281795127 0.491112632050166 GO:0071837 HMG box domain binding 1/256 13/18639 0.0769230769230769 5.60066105769231 0.164601281795127 0.491112632050166 GO:0097157 pre-mRNA intronic binding 1/256 13/18639 0.0769230769230769 5.60066105769231 0.164601281795127 0.491112632050166 GO:0004864 protein phosphatase inhibitor activity 2/256 53/18639 0.0377358490566038 2.74749410377358 0.16475629128792 0.491112632050166 GO:0016860 intramolecular oxidoreductase activity 2/256 53/18639 0.0377358490566038 2.74749410377358 0.16475629128792 0.491112632050166 GO:0008238 exopeptidase activity 3/256 102/18639 0.0294117647058824 2.14142922794118 0.165309153925383 0.491112632050166 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/256 54/18639 0.037037037037037 2.69661458333333 0.169630523629911 0.492749099986414 GO:0005096 GTPase activator activity 6/256 271/18639 0.022140221402214 1.61199838560886 0.170430947435673 0.492749099986414 GO:0005344 oxygen carrier activity 1/256 14/18639 0.0714285714285714 5.20061383928571 0.176083192664902 0.492749099986414 GO:0008559 ABC-type xenobiotic transporter activity 1/256 14/18639 0.0714285714285714 5.20061383928571 0.176083192664902 0.492749099986414 GO:0019992 diacylglycerol binding 1/256 14/18639 0.0714285714285714 5.20061383928571 0.176083192664902 0.492749099986414 GO:0030983 mismatched DNA binding 1/256 14/18639 0.0714285714285714 5.20061383928571 0.176083192664902 0.492749099986414 GO:0032036 myosin heavy chain binding 1/256 14/18639 0.0714285714285714 5.20061383928571 0.176083192664902 0.492749099986414 GO:0044548 S100 protein binding 1/256 14/18639 0.0714285714285714 5.20061383928571 0.176083192664902 0.492749099986414 GO:0005126 cytokine receptor binding 6/256 275/18639 0.0218181818181818 1.58855113636364 0.17845929240485 0.492749099986414 GO:0019212 phosphatase inhibitor activity 2/256 56/18639 0.0357142857142857 2.60030691964286 0.179449697407555 0.492749099986414 GO:0019888 protein phosphatase regulator activity 3/256 107/18639 0.0280373831775701 2.04136244158878 0.182252391691759 0.492749099986414 GO:0016504 peptidase activator activity 2/256 57/18639 0.0350877192982456 2.5546875 0.184391531815904 0.492749099986414 GO:0001217 DNA-binding transcription repressor activity 6/256 278/18639 0.0215827338129496 1.57140849820144 0.184579629733577 0.492749099986414 GO:0000774 adenyl-nucleotide exchange factor activity 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0004129 cytochrome-c oxidase activity 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0004467 long-chain fatty acid-CoA ligase activity 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0004559 alpha-mannosidase activity 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0004953 icosanoid receptor activity 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0005041 low-density lipoprotein particle receptor activity 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0005523 tropomyosin binding 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0050700 CARD domain binding 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0120283 protein serine/threonine kinase binding 1/256 15/18639 0.0666666666666667 4.85390625 0.187407901533508 0.492749099986414 GO:0001786 phosphatidylserine binding 2/256 59/18639 0.0338983050847458 2.46808792372881 0.194332211165791 0.492749099986414 GO:0045309 protein phosphorylated amino acid binding 2/256 59/18639 0.0338983050847458 2.46808792372881 0.194332211165791 0.492749099986414 GO:0070063 RNA polymerase binding 2/256 59/18639 0.0338983050847458 2.46808792372881 0.194332211165791 0.492749099986414 GO:0031267 small GTPase binding 6/256 283/18639 0.0212014134275618 1.54364509717315 0.194961273557826 0.492749099986414 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/256 16/18639 0.0625 4.550537109375 0.198577552371536 0.492749099986414 GO:0005159 insulin-like growth factor receptor binding 1/256 16/18639 0.0625 4.550537109375 0.198577552371536 0.492749099986414 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/256 16/18639 0.0625 4.550537109375 0.198577552371536 0.492749099986414 GO:0005521 lamin binding 1/256 16/18639 0.0625 4.550537109375 0.198577552371536 0.492749099986414 GO:0015562 efflux transmembrane transporter activity 1/256 16/18639 0.0625 4.550537109375 0.198577552371536 0.492749099986414 GO:0015923 mannosidase activity 1/256 16/18639 0.0625 4.550537109375 0.198577552371536 0.492749099986414 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/256 16/18639 0.0625 4.550537109375 0.198577552371536 0.492749099986414 GO:0055102 lipase inhibitor activity 1/256 16/18639 0.0625 4.550537109375 0.198577552371536 0.492749099986414 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/256 60/18639 0.0333333333333333 2.426953125 0.199328172437326 0.492749099986414 GO:0015026 coreceptor activity 2/256 61/18639 0.0327868852459016 2.38716700819672 0.204339351833465 0.492749099986414 GO:0019905 syntaxin binding 2/256 61/18639 0.0327868852459016 2.38716700819672 0.204339351833465 0.492749099986414 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0015278 intracellularly gated calcium channel activity 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0016018 cyclosporin A binding 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0019198 transmembrane receptor protein phosphatase activity 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0030169 low-density lipoprotein particle binding 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0036041 long-chain fatty acid binding 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0048038 quinone binding 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0051787 misfolded protein binding 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0070402 NADPH binding 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:1990226 histone methyltransferase binding 1/256 17/18639 0.0588235294117647 4.28285845588235 0.209594260022982 0.492749099986414 GO:0005085 guanyl-nucleotide exchange factor activity 5/256 230/18639 0.0217391304347826 1.58279551630435 0.210142998523618 0.492749099986414 GO:0004857 enzyme inhibitor activity 8/256 416/18639 0.0192307692307692 1.40016526442308 0.214525481186003 0.499181679792249 GO:0019208 phosphatase regulator activity 3/256 117/18639 0.0256410256410256 1.86688701923077 0.217394221673007 0.499181679792249 GO:0008409 5'-3' exonuclease activity 1/256 18/18639 0.0555555555555556 4.044921875 0.220460110599403 0.499181679792249 GO:0017075 syntaxin-1 binding 1/256 18/18639 0.0555555555555556 4.044921875 0.220460110599403 0.499181679792249 GO:0030228 lipoprotein particle receptor activity 1/256 18/18639 0.0555555555555556 4.044921875 0.220460110599403 0.499181679792249 GO:0032393 MHC class I receptor activity 1/256 18/18639 0.0555555555555556 4.044921875 0.220460110599403 0.499181679792249 GO:0070064 proline-rich region binding 1/256 18/18639 0.0555555555555556 4.044921875 0.220460110599403 0.499181679792249 GO:0004252 serine-type endopeptidase activity 4/256 176/18639 0.0227272727272727 1.65474076704545 0.223447841217042 0.499181679792249 GO:0019843 rRNA binding 2/256 65/18639 0.0307692307692308 2.24026442307692 0.224509684626144 0.499181679792249 GO:0106310 protein serine kinase activity 7/256 361/18639 0.0193905817174515 1.41180098684211 0.229166984772632 0.499181679792249 GO:0008235 metalloexopeptidase activity 2/256 66/18639 0.0303030303030303 2.20632102272727 0.229577320928099 0.499181679792249 GO:0015245 fatty acid transmembrane transporter activity 1/256 19/18639 0.0526315789473684 3.83203125 0.231177161868753 0.499181679792249 GO:0031420 alkali metal ion binding 1/256 19/18639 0.0526315789473684 3.83203125 0.231177161868753 0.499181679792249 GO:0034987 immunoglobulin receptor binding 1/256 19/18639 0.0526315789473684 3.83203125 0.231177161868753 0.499181679792249 GO:0043395 heparan sulfate proteoglycan binding 1/256 19/18639 0.0526315789473684 3.83203125 0.231177161868753 0.499181679792249 GO:0050145 nucleoside monophosphate kinase activity 1/256 19/18639 0.0526315789473684 3.83203125 0.231177161868753 0.499181679792249 GO:0016853 isomerase activity 4/256 180/18639 0.0222222222222222 1.61796875 0.235159064697135 0.499181679792249 GO:0031625 ubiquitin protein ligase binding 6/256 302/18639 0.0198675496688742 1.44652835264901 0.236270498970334 0.499181679792249 GO:0016004 phospholipase activator activity 1/256 20/18639 0.05 3.6404296875 0.241747443638978 0.499181679792249 GO:0016505 peptidase activator activity involved in apoptotic process 1/256 20/18639 0.05 3.6404296875 0.241747443638978 0.499181679792249 GO:0042288 MHC class I protein binding 1/256 20/18639 0.05 3.6404296875 0.241747443638978 0.499181679792249 GO:0140664 ATP-dependent DNA damage sensor activity 1/256 20/18639 0.05 3.6404296875 0.241747443638978 0.499181679792249 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/256 243/18639 0.0205761316872428 1.49811921296296 0.242602255922768 0.499181679792249 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0004711 ribosomal protein S6 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0035175 histone H3S10 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0035979 histone H2AXS139 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0044022 histone H3S28 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0044023 histone H4S1 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0044024 histone H2AS1 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0044025 histone H2BS14 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0072354 histone H3T3 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0072371 histone H2AS121 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0140823 histone H2BS36 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0140855 histone H3S57 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0140995 histone H2A kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0140997 histone H4 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:0140998 histone H2B kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:1990244 histone H2AT120 kinase activity 5/256 245/18639 0.0204081632653061 1.48588966836735 0.24771391048649 0.499181679792249 GO:1901981 phosphatidylinositol phosphate binding 4/256 185/18639 0.0216216216216216 1.57423986486487 0.249999172023319 0.499181679792249 GO:0004677 DNA-dependent protein kinase activity 5/256 246/18639 0.0203252032520325 1.47984946646341 0.250280278619998 0.499181679792249 GO:0140857 histone H3T45 kinase activity 5/256 246/18639 0.0203252032520325 1.47984946646341 0.250280278619998 0.499181679792249 GO:0001846 opsonin binding 1/256 21/18639 0.0476190476190476 3.46707589285714 0.252172958136449 0.499181679792249 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/256 21/18639 0.0476190476190476 3.46707589285714 0.252172958136449 0.499181679792249 GO:0010314 phosphatidylinositol-5-phosphate binding 1/256 21/18639 0.0476190476190476 3.46707589285714 0.252172958136449 0.499181679792249 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/256 21/18639 0.0476190476190476 3.46707589285714 0.252172958136449 0.499181679792249 GO:0072542 protein phosphatase activator activity 1/256 21/18639 0.0476190476190476 3.46707589285714 0.252172958136449 0.499181679792249 GO:0035402 histone H3T11 kinase activity 5/256 247/18639 0.0202429149797571 1.47385817307692 0.252853465254244 0.499181679792249 GO:0004679 AMP-activated protein kinase activity 5/256 248/18639 0.0201612903225806 1.46791519657258 0.255433313924083 0.502653338011379 GO:0008093 cytoskeletal anchor activity 1/256 22/18639 0.0454545454545455 3.30948153409091 0.262455680379283 0.508300241747219 GO:0015377 chloride:monoatomic cation symporter activity 1/256 22/18639 0.0454545454545455 3.30948153409091 0.262455680379283 0.508300241747219 GO:0031683 G-protein beta/gamma-subunit complex binding 1/256 22/18639 0.0454545454545455 3.30948153409091 0.262455680379283 0.508300241747219 GO:0070034 telomerase RNA binding 1/256 22/18639 0.0454545454545455 3.30948153409091 0.262455680379283 0.508300241747219 GO:0140517 protein-RNA adaptor activity 1/256 22/18639 0.0454545454545455 3.30948153409091 0.262455680379283 0.508300241747219 GO:0019902 phosphatase binding 4/256 190/18639 0.0210526315789474 1.5328125 0.265033530984127 0.511673567704372 GO:0031072 heat shock protein binding 3/256 131/18639 0.0229007633587786 1.6673723759542 0.268591814498582 0.516912548657649 GO:0048029 monosaccharide binding 2/256 74/18639 0.027027027027027 1.96779983108108 0.270298128871772 0.517818906509732 GO:0031681 G-protein beta-subunit binding 1/256 23/18639 0.0434782608695652 3.1655910326087 0.272597558545631 0.517818906509732 GO:0043274 phospholipase binding 1/256 23/18639 0.0434782608695652 3.1655910326087 0.272597558545631 0.517818906509732 GO:0099186 structural constituent of postsynapse 1/256 23/18639 0.0434782608695652 3.1655910326087 0.272597558545631 0.517818906509732 GO:0019887 protein kinase regulator activity 5/256 255/18639 0.0196078431372549 1.42761948529412 0.273665675672529 0.517818906509732 GO:0003725 double-stranded RNA binding 2/256 75/18639 0.0266666666666667 1.9415625 0.275394833454602 0.517818906509732 GO:0008236 serine-type peptidase activity 4/256 194/18639 0.0206185567010309 1.5012081185567 0.277180201987113 0.517818906509732 GO:0017022 myosin binding 2/256 76/18639 0.0263157894736842 1.916015625 0.28048973492648 0.517818906509732 GO:0044389 ubiquitin-like protein ligase binding 6/256 322/18639 0.0186335403726708 1.35668187111801 0.282333857107195 0.517818906509732 GO:0005540 hyaluronic acid binding 1/256 24/18639 0.0416666666666667 3.03369140625 0.28260051433701 0.517818906509732 GO:0030215 semaphorin receptor binding 1/256 24/18639 0.0416666666666667 3.03369140625 0.28260051433701 0.517818906509732 GO:0048027 mRNA 5'-UTR binding 1/256 24/18639 0.0416666666666667 3.03369140625 0.28260051433701 0.517818906509732 GO:0050431 transforming growth factor beta binding 1/256 24/18639 0.0416666666666667 3.03369140625 0.28260051433701 0.517818906509732 GO:0060229 lipase activator activity 1/256 24/18639 0.0416666666666667 3.03369140625 0.28260051433701 0.517818906509732 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/256 24/18639 0.0416666666666667 3.03369140625 0.28260051433701 0.517818906509732 GO:0140612 DNA damage sensor activity 1/256 24/18639 0.0416666666666667 3.03369140625 0.28260051433701 0.517818906509732 GO:0017171 serine hydrolase activity 4/256 198/18639 0.0202020202020202 1.47088068181818 0.289416072183366 0.524071317911825 GO:0001848 complement binding 1/256 25/18639 0.04 2.91234375 0.292466443336727 0.524071317911825 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/256 25/18639 0.04 2.91234375 0.292466443336727 0.524071317911825 GO:0015645 fatty acid ligase activity 1/256 25/18639 0.04 2.91234375 0.292466443336727 0.524071317911825 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/256 25/18639 0.04 2.91234375 0.292466443336727 0.524071317911825 GO:0019211 phosphatase activator activity 1/256 25/18639 0.04 2.91234375 0.292466443336727 0.524071317911825 GO:0120515 fatty acid-CoA ligase activity 1/256 25/18639 0.04 2.91234375 0.292466443336727 0.524071317911825 GO:0022804 active transmembrane transporter activity 8/256 457/18639 0.0175054704595186 1.27454868708972 0.292863383538961 0.524071317911825 GO:0046332 SMAD binding 2/256 79/18639 0.0253164556962025 1.84325553797468 0.295754659614074 0.527702191497997 GO:0004529 DNA exonuclease activity 1/256 26/18639 0.0384615384615385 2.80033052884615 0.30219721536347 0.528413416578411 GO:0005160 transforming growth factor beta receptor binding 1/256 26/18639 0.0384615384615385 2.80033052884615 0.30219721536347 0.528413416578411 GO:0008143 poly(A) binding 1/256 26/18639 0.0384615384615385 2.80033052884615 0.30219721536347 0.528413416578411 GO:0008157 protein phosphatase 1 binding 1/256 26/18639 0.0384615384615385 2.80033052884615 0.30219721536347 0.528413416578411 GO:0015216 purine nucleotide transmembrane transporter activity 1/256 26/18639 0.0384615384615385 2.80033052884615 0.30219721536347 0.528413416578411 GO:0030247 polysaccharide binding 1/256 26/18639 0.0384615384615385 2.80033052884615 0.30219721536347 0.528413416578411 GO:0043548 phosphatidylinositol 3-kinase binding 1/256 26/18639 0.0384615384615385 2.80033052884615 0.30219721536347 0.528413416578411 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 5/256 268/18639 0.0186567164179104 1.3583692863806 0.30819005350676 0.536006575814394 GO:0020037 heme binding 3/256 142/18639 0.0211267605633803 1.53820972711268 0.309714100877589 0.536006575814394 GO:0001671 ATPase activator activity 1/256 27/18639 0.037037037037037 2.69661458333333 0.311794674820137 0.536006575814394 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/256 27/18639 0.037037037037037 2.69661458333333 0.311794674820137 0.536006575814394 GO:0005044 scavenger receptor activity 1/256 27/18639 0.037037037037037 2.69661458333333 0.311794674820137 0.536006575814394 GO:0016405 CoA-ligase activity 1/256 27/18639 0.037037037037037 2.69661458333333 0.311794674820137 0.536006575814394 GO:0019903 protein phosphatase binding 3/256 144/18639 0.0208333333333333 1.516845703125 0.31722636071498 0.542271481978656 GO:0004860 protein kinase inhibitor activity 2/256 84/18639 0.0238095238095238 1.73353794642857 0.321080146374067 0.542271481978656 GO:0016866 intramolecular transferase activity 1/256 28/18639 0.0357142857142857 2.60030691964286 0.321260641037957 0.542271481978656 GO:0045499 chemorepellent activity 1/256 28/18639 0.0357142857142857 2.60030691964286 0.321260641037957 0.542271481978656 GO:0051019 mitogen-activated protein kinase binding 1/256 28/18639 0.0357142857142857 2.60030691964286 0.321260641037957 0.542271481978656 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/256 28/18639 0.0357142857142857 2.60030691964286 0.321260641037957 0.542271481978656 GO:0016791 phosphatase activity 5/256 273/18639 0.0183150183150183 1.33349072802198 0.321641418232438 0.542271481978656 GO:0004181 metallocarboxypeptidase activity 1/256 29/18639 0.0344827586206897 2.5106411637931 0.330596908615963 0.553087264964399 GO:0099604 ligand-gated calcium channel activity 1/256 29/18639 0.0344827586206897 2.5106411637931 0.330596908615963 0.553087264964399 GO:0050660 flavin adenine dinucleotide binding 2/256 86/18639 0.0232558139534884 1.69322311046512 0.331151713580972 0.553087264964399 GO:0008081 phosphoric diester hydrolase activity 2/256 87/18639 0.0229885057471264 1.67376077586207 0.336172088828802 0.553087264964399 GO:0001965 G-protein alpha-subunit binding 1/256 30/18639 0.0333333333333333 2.426953125 0.339805247755905 0.553087264964399 GO:0001968 fibronectin binding 1/256 30/18639 0.0333333333333333 2.426953125 0.339805247755905 0.553087264964399 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/256 30/18639 0.0333333333333333 2.426953125 0.339805247755905 0.553087264964399 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/256 30/18639 0.0333333333333333 2.426953125 0.339805247755905 0.553087264964399 GO:0015215 nucleotide transmembrane transporter activity 1/256 30/18639 0.0333333333333333 2.426953125 0.339805247755905 0.553087264964399 GO:0031624 ubiquitin conjugating enzyme binding 1/256 30/18639 0.0333333333333333 2.426953125 0.339805247755905 0.553087264964399 GO:0033612 receptor serine/threonine kinase binding 1/256 30/18639 0.0333333333333333 2.426953125 0.339805247755905 0.553087264964399 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/256 30/18639 0.0333333333333333 2.426953125 0.339805247755905 0.553087264964399 GO:0098918 structural constituent of synapse 1/256 30/18639 0.0333333333333333 2.426953125 0.339805247755905 0.553087264964399 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/256 89/18639 0.0224719101123595 1.6361481741573 0.346178726096736 0.557926695589604 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/256 89/18639 0.0224719101123595 1.6361481741573 0.346178726096736 0.557926695589604 GO:0046906 tetrapyrrole binding 3/256 152/18639 0.0197368421052632 1.43701171875 0.347278551449856 0.557926695589604 GO:0005164 tumor necrosis factor receptor binding 1/256 31/18639 0.032258064516129 2.34866431451613 0.348887404592623 0.557926695589604 GO:0016878 acid-thiol ligase activity 1/256 31/18639 0.032258064516129 2.34866431451613 0.348887404592623 0.557926695589604 GO:0072349 modified amino acid transmembrane transporter activity 1/256 31/18639 0.032258064516129 2.34866431451613 0.348887404592623 0.557926695589604 GO:0016887 ATP hydrolysis activity 7/256 417/18639 0.0167865707434053 1.22220660971223 0.34916000720722 0.557926695589604 GO:0019210 kinase inhibitor activity 2/256 90/18639 0.0222222222222222 1.61796875 0.351163729085424 0.558213512208518 GO:0140793 histone H2AXY142 phosphatase activity 2/256 90/18639 0.0222222222222222 1.61796875 0.351163729085424 0.558213512208518 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/256 91/18639 0.021978021978022 1.60018887362637 0.3561357144137 0.558676536046502 GO:0030515 snoRNA binding 1/256 32/18639 0.03125 2.2752685546875 0.357845101519982 0.558676536046502 GO:0042910 xenobiotic transmembrane transporter activity 1/256 32/18639 0.03125 2.2752685546875 0.357845101519982 0.558676536046502 GO:0043425 bHLH transcription factor binding 1/256 32/18639 0.03125 2.2752685546875 0.357845101519982 0.558676536046502 GO:0070717 poly-purine tract binding 1/256 32/18639 0.03125 2.2752685546875 0.357845101519982 0.558676536046502 GO:0071813 lipoprotein particle binding 1/256 32/18639 0.03125 2.2752685546875 0.357845101519982 0.558676536046502 GO:0071814 protein-lipid complex binding 1/256 32/18639 0.03125 2.2752685546875 0.357845101519982 0.558676536046502 GO:0019207 kinase regulator activity 5/256 287/18639 0.0174216027874564 1.26844239982578 0.359606648899734 0.559998140271342 GO:0043178 alcohol binding 2/256 92/18639 0.0217391304347826 1.58279551630435 0.361094100141535 0.560887282453348 GO:0051219 phosphoprotein binding 2/256 93/18639 0.021505376344086 1.56577620967742 0.366038322637145 0.56383965567233 GO:0019239 deaminase activity 1/256 33/18639 0.0303030303030303 2.20632102272727 0.366680037512398 0.56383965567233 GO:0030296 protein tyrosine kinase activator activity 1/256 33/18639 0.0303030303030303 2.20632102272727 0.366680037512398 0.56383965567233 GO:0140311 protein sequestering activity 1/256 33/18639 0.0303030303030303 2.20632102272727 0.366680037512398 0.56383965567233 GO:0008175 tRNA methyltransferase activity 1/256 34/18639 0.0294117647058824 2.14142922794118 0.375393888442035 0.5729203484452 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/256 34/18639 0.0294117647058824 2.14142922794118 0.375393888442035 0.5729203484452 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/256 34/18639 0.0294117647058824 2.14142922794118 0.375393888442035 0.5729203484452 GO:0016407 acetyltransferase activity 2/256 96/18639 0.0208333333333333 1.516845703125 0.380780640903478 0.579695901076936 GO:0005154 epidermal growth factor receptor binding 1/256 35/18639 0.0285714285714286 2.08024553571429 0.383988307391717 0.580248997836372 GO:0043015 gamma-tubulin binding 1/256 35/18639 0.0285714285714286 2.08024553571429 0.383988307391717 0.580248997836372 GO:0061631 ubiquitin conjugating enzyme activity 1/256 35/18639 0.0285714285714286 2.08024553571429 0.383988307391717 0.580248997836372 GO:0004674 protein serine/threonine kinase activity 7/256 433/18639 0.0161662817551963 1.17704424076212 0.385004742409508 0.580351976242903 GO:0004033 aldo-keto reductase (NADPH) activity 1/256 36/18639 0.0277777777777778 2.0224609375 0.392464924963622 0.581570300430355 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/256 36/18639 0.0277777777777778 2.0224609375 0.392464924963622 0.581570300430355 GO:0005484 SNAP receptor activity 1/256 36/18639 0.0277777777777778 2.0224609375 0.392464924963622 0.581570300430355 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/256 36/18639 0.0277777777777778 2.0224609375 0.392464924963622 0.581570300430355 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/256 36/18639 0.0277777777777778 2.0224609375 0.392464924963622 0.581570300430355 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/256 36/18639 0.0277777777777778 2.0224609375 0.392464924963622 0.581570300430355 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/256 36/18639 0.0277777777777778 2.0224609375 0.392464924963622 0.581570300430355 GO:0043394 proteoglycan binding 1/256 37/18639 0.027027027027027 1.96779983108108 0.400825349583807 0.592524429819541 GO:0016874 ligase activity 3/256 167/18639 0.0179640718562874 1.30793880988024 0.403158978666175 0.594538060105299 GO:0042887 amide transmembrane transporter activity 1/256 38/18639 0.0263157894736842 1.916015625 0.409071167802631 0.600363440516091 GO:0043531 ADP binding 1/256 38/18639 0.0263157894736842 1.916015625 0.409071167802631 0.600363440516091 GO:0141108 transporter regulator activity 3/256 170/18639 0.0176470588235294 1.28485753676471 0.414191533176817 0.606423967234957 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/256 39/18639 0.0256410256410256 1.86688701923077 0.417203944591111 0.607925747832762 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/256 39/18639 0.0256410256410256 1.86688701923077 0.417203944591111 0.607925747832762 GO:0071949 FAD binding 1/256 40/18639 0.025 1.82021484375 0.425225223633298 0.61646408116323 GO:0000149 SNARE binding 2/256 106/18639 0.0188679245283019 1.37374705188679 0.428798904725993 0.61646408116323 GO:0004497 monooxygenase activity 2/256 106/18639 0.0188679245283019 1.37374705188679 0.428798904725993 0.61646408116323 GO:0008013 beta-catenin binding 2/256 106/18639 0.0188679245283019 1.37374705188679 0.428798904725993 0.61646408116323 GO:0004721 phosphoprotein phosphatase activity 3/256 175/18639 0.0171428571428571 1.24814732142857 0.432432320342255 0.61646408116323 GO:0008227 G protein-coupled amine receptor activity 1/256 41/18639 0.024390243902439 1.7758193597561 0.433136527614688 0.61646408116323 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/256 41/18639 0.024390243902439 1.7758193597561 0.433136527614688 0.61646408116323 GO:0042287 MHC protein binding 1/256 41/18639 0.024390243902439 1.7758193597561 0.433136527614688 0.61646408116323 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/256 41/18639 0.024390243902439 1.7758193597561 0.433136527614688 0.61646408116323 GO:0140828 metal cation:monoatomic cation antiporter activity 1/256 41/18639 0.024390243902439 1.7758193597561 0.433136527614688 0.61646408116323 GO:0016859 cis-trans isomerase activity 1/256 42/18639 0.0238095238095238 1.73353794642857 0.440939358506754 0.624664091217901 GO:0051879 Hsp90 protein binding 1/256 42/18639 0.0238095238095238 1.73353794642857 0.440939358506754 0.624664091217901 GO:0004620 phospholipase activity 2/256 109/18639 0.018348623853211 1.3359375 0.44282494978353 0.625083829228932 GO:0005319 lipid transporter activity 3/256 178/18639 0.0168539325842697 1.22711113061798 0.443278401773459 0.625083829228932 GO:1902936 phosphatidylinositol bisphosphate binding 2/256 111/18639 0.018018018018018 1.31186655405405 0.452069703306828 0.634568205217352 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/256 181/18639 0.0165745856353591 1.20677227209945 0.454043467809824 0.634568205217352 GO:0001046 core promoter sequence-specific DNA binding 1/256 44/18639 0.0227272727272727 1.65474076704545 0.456225507019011 0.634568205217352 GO:0001223 transcription coactivator binding 1/256 44/18639 0.0227272727272727 1.65474076704545 0.456225507019011 0.634568205217352 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/256 44/18639 0.0227272727272727 1.65474076704545 0.456225507019011 0.634568205217352 GO:0043014 alpha-tubulin binding 1/256 44/18639 0.0227272727272727 1.65474076704545 0.456225507019011 0.634568205217352 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/256 45/18639 0.0222222222222222 1.61796875 0.463711727519314 0.640562778290492 GO:0046915 transition metal ion transmembrane transporter activity 1/256 45/18639 0.0222222222222222 1.61796875 0.463711727519314 0.640562778290492 GO:0141110 transporter inhibitor activity 1/256 45/18639 0.0222222222222222 1.61796875 0.463711727519314 0.640562778290492 GO:0061135 endopeptidase regulator activity 3/256 184/18639 0.016304347826087 1.18709663722826 0.464722015622514 0.640562778290492 GO:0030291 protein serine/threonine kinase inhibitor activity 1/256 46/18639 0.0217391304347826 1.58279551630435 0.47109528123315 0.647888341830759 GO:0005504 fatty acid binding 1/256 47/18639 0.0212765957446809 1.54911901595745 0.478377570697158 0.651190600270655 GO:0043495 protein-membrane adaptor activity 1/256 47/18639 0.0212765957446809 1.54911901595745 0.478377570697158 0.651190600270655 GO:0140359 ABC-type transporter activity 1/256 47/18639 0.0212765957446809 1.54911901595745 0.478377570697158 0.651190600270655 GO:0140938 histone H3 methyltransferase activity 1/256 47/18639 0.0212765957446809 1.54911901595745 0.478377570697158 0.651190600270655 GO:0046943 carboxylic acid transmembrane transporter activity 3/256 188/18639 0.0159574468085106 1.16183926196809 0.47881661784607 0.651190600270655 GO:0005342 organic acid transmembrane transporter activity 3/256 189/18639 0.0158730158730159 1.15569196428571 0.482313456790504 0.654491874846538 GO:0004175 endopeptidase activity 6/256 405/18639 0.0148148148148148 1.07864583333333 0.483463474697087 0.654600987864198 GO:0008188 neuropeptide receptor activity 1/256 48/18639 0.0208333333333333 1.516845703125 0.485559979362258 0.655988316489408 GO:0035254 glutamate receptor binding 1/256 49/18639 0.0204081632653061 1.48588966836735 0.492643871852347 0.664092620206248 GO:0003697 single-stranded DNA binding 2/256 121/18639 0.0165289256198347 1.20344783057851 0.496941648221777 0.667628654284603 GO:0015605 organophosphate ester transmembrane transporter activity 1/256 50/18639 0.02 1.456171875 0.499630594219523 0.667628654284603 GO:0032813 tumor necrosis factor receptor superfamily binding 1/256 50/18639 0.02 1.456171875 0.499630594219523 0.667628654284603 GO:0048020 CCR chemokine receptor binding 1/256 50/18639 0.02 1.456171875 0.499630594219523 0.667628654284603 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/256 122/18639 0.0163934426229508 1.19358350409836 0.501299581489049 0.668399441985398 GO:0005080 protein kinase C binding 1/256 52/18639 0.0192307692307692 1.40016526442308 0.513317821441693 0.679979451779905 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/256 52/18639 0.0192307692307692 1.40016526442308 0.513317821441693 0.679979451779905 GO:0030159 signaling receptor complex adaptor activity 1/256 52/18639 0.0192307692307692 1.40016526442308 0.513317821441693 0.679979451779905 GO:0016829 lyase activity 3/256 200/18639 0.015 1.09212890625 0.520014389431941 0.681483528496728 GO:0005544 calcium-dependent phospholipid binding 1/256 53/18639 0.0188679245283019 1.37374705188679 0.520020927790804 0.681483528496728 GO:0017046 peptide hormone binding 1/256 53/18639 0.0188679245283019 1.37374705188679 0.520020927790804 0.681483528496728 GO:0034212 protein N-acetyltransferase activity 1/256 53/18639 0.0188679245283019 1.37374705188679 0.520020927790804 0.681483528496728 GO:0051018 protein kinase A binding 1/256 53/18639 0.0188679245283019 1.37374705188679 0.520020927790804 0.681483528496728 GO:1901681 sulfur compound binding 4/256 275/18639 0.0145454545454545 1.05903409090909 0.524083708203073 0.682836494290414 GO:0015485 cholesterol binding 1/256 54/18639 0.0185185185185185 1.34830729166667 0.526632067491953 0.682836494290414 GO:0017069 snRNA binding 1/256 54/18639 0.0185185185185185 1.34830729166667 0.526632067491953 0.682836494290414 GO:0050661 NADP binding 1/256 54/18639 0.0185185185185185 1.34830729166667 0.526632067491953 0.682836494290414 GO:0140463 chromatin-protein adaptor activity 1/256 54/18639 0.0185185185185185 1.34830729166667 0.526632067491953 0.682836494290414 GO:0035591 signaling adaptor activity 2/256 129/18639 0.0155038759689922 1.12881540697674 0.53111770926184 0.687196697818702 GO:0140313 molecular sequestering activity 1/256 55/18639 0.0181818181818182 1.32379261363636 0.533152497447404 0.688374110628294 GO:0016298 lipase activity 2/256 130/18639 0.0153846153846154 1.12013221153846 0.535277655520162 0.689663000375451 GO:0005516 calmodulin binding 3/256 207/18639 0.0144927536231884 1.05519701086957 0.543220859174484 0.695889591774773 GO:0005179 hormone activity 2/256 132/18639 0.0151515151515152 1.10316051136364 0.543521609261996 0.695889591774773 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/256 132/18639 0.0151515151515152 1.10316051136364 0.543521609261996 0.695889591774773 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/256 57/18639 0.0175438596491228 1.27734375 0.545926170405847 0.697509011040456 GO:0051087 protein-folding chaperone binding 2/256 134/18639 0.0149253731343284 1.08669542910448 0.551663730128813 0.703371255914237 GO:0008094 ATP-dependent activity, acting on DNA 3/256 210/18639 0.0142857142857143 1.04012276785714 0.552967008819565 0.703567171304727 GO:0036002 pre-mRNA binding 1/256 59/18639 0.0169491525423729 1.23404396186441 0.55835166381325 0.706264933532578 GO:0070888 E-box binding 1/256 59/18639 0.0169491525423729 1.23404396186441 0.55835166381325 0.706264933532578 GO:0002020 protease binding 2/256 136/18639 0.0147058823529412 1.07071461397059 0.559703419547877 0.706264933532578 GO:0140789 histone phosphatase activity 2/256 136/18639 0.0147058823529412 1.07071461397059 0.559703419547877 0.706264933532578 GO:0016922 nuclear receptor binding 2/256 137/18639 0.0145985401459854 1.06289917883212 0.563684695068072 0.709312785079556 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/256 60/18639 0.0166666666666667 1.2134765625 0.564436807734876 0.709312785079556 GO:0016836 hydro-lyase activity 1/256 61/18639 0.0163934426229508 1.19358350409836 0.570438431999899 0.713879077430687 GO:0030295 protein kinase activator activity 2/256 139/18639 0.0143884892086331 1.04760566546763 0.571569849576857 0.713879077430687 GO:0070851 growth factor receptor binding 2/256 139/18639 0.0143884892086331 1.04760566546763 0.571569849576857 0.713879077430687 GO:0046982 protein heterodimerization activity 5/256 369/18639 0.013550135501355 0.98656631097561 0.574488005716876 0.716062442970934 GO:1901682 sulfur compound transmembrane transporter activity 1/256 63/18639 0.0158730158730159 1.15569196428571 0.582195673560243 0.724194618331034 GO:0001664 G protein-coupled receptor binding 4/256 297/18639 0.0134680134680135 0.980587121212121 0.584925366352754 0.726114247886178 GO:0004536 DNA nuclease activity 1/256 64/18639 0.015625 1.13763427734375 0.587953528188181 0.728395868929487 GO:0038024 cargo receptor activity 1/256 65/18639 0.0153846153846154 1.12013221153846 0.593632338243838 0.733945436374199 GO:0005525 GTP binding 5/256 378/18639 0.0132275132275132 0.963076636904762 0.595911286380723 0.735277635614924 GO:0015085 calcium ion transmembrane transporter activity 2/256 147/18639 0.0136054421768707 0.990593112244898 0.602073797351589 0.735715225857843 GO:0061134 peptidase regulator activity 3/256 226/18639 0.0132743362831858 0.966485757743363 0.602806677218495 0.735715225857843 GO:0008173 RNA methyltransferase activity 1/256 67/18639 0.0149253731343284 1.08669542910448 0.604757133661334 0.735715225857843 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/256 67/18639 0.0149253731343284 1.08669542910448 0.604757133661334 0.735715225857843 GO:0042054 histone methyltransferase activity 1/256 67/18639 0.0149253731343284 1.08669542910448 0.604757133661334 0.735715225857843 GO:0050840 extracellular matrix binding 1/256 67/18639 0.0149253731343284 1.08669542910448 0.604757133661334 0.735715225857843 GO:0019209 kinase activator activity 2/256 148/18639 0.0135135135135135 0.983899915540541 0.605769910308767 0.735715225857843 GO:0008509 monoatomic anion transmembrane transporter activity 2/256 149/18639 0.0134228187919463 0.977296560402685 0.609440050176778 0.735715225857843 GO:0030145 manganese ion binding 1/256 68/18639 0.0147058823529412 1.07071461397059 0.610205236923379 0.735715225857843 GO:0032934 sterol binding 1/256 68/18639 0.0147058823529412 1.07071461397059 0.610205236923379 0.735715225857843 GO:1990841 promoter-specific chromatin binding 1/256 68/18639 0.0147058823529412 1.07071461397059 0.610205236923379 0.735715225857843 GO:0008080 N-acetyltransferase activity 1/256 69/18639 0.0144927536231884 1.05519701086957 0.61557853181044 0.735715225857843 GO:0016279 protein-lysine N-methyltransferase activity 1/256 69/18639 0.0144927536231884 1.05519701086957 0.61557853181044 0.735715225857843 GO:0000510 H3-H4 histone complex chaperone activity 2/256 151/18639 0.0132450331125828 0.964352235099338 0.61670246873378 0.735715225857843 GO:0140584 chromatin extrusion motor activity 2/256 151/18639 0.0132450331125828 0.964352235099338 0.61670246873378 0.735715225857843 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/256 151/18639 0.0132450331125828 0.964352235099338 0.61670246873378 0.735715225857843 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/256 151/18639 0.0132450331125828 0.964352235099338 0.61670246873378 0.735715225857843 GO:0015616 DNA translocase activity 2/256 152/18639 0.0131578947368421 0.9580078125 0.620294787630899 0.736390235326291 GO:0140674 ATP-dependent histone chaperone activity 2/256 152/18639 0.0131578947368421 0.9580078125 0.620294787630899 0.736390235326291 GO:0016278 lysine N-methyltransferase activity 1/256 70/18639 0.0142857142857143 1.04012276785714 0.620878041549617 0.736390235326291 GO:0061775 cohesin loader activity 2/256 153/18639 0.0130718954248366 0.951746323529412 0.623861213606474 0.738403630293419 GO:0140299 molecular sensor activity 1/256 71/18639 0.0140845070422535 1.02547315140845 0.626104775426687 0.738403630293419 GO:0005125 cytokine activity 3/256 234/18639 0.0128205128205128 0.933443509615385 0.626318542823327 0.738403630293419 GO:0005506 iron ion binding 2/256 154/18639 0.012987012987013 0.945566152597403 0.627401777373493 0.738403630293419 GO:0140658 ATP-dependent chromatin remodeler activity 2/256 158/18639 0.0126582278481013 0.921627768987342 0.641306163208007 0.751937211230113 GO:0035064 methylated histone binding 1/256 74/18639 0.0135135135135135 0.983899915540541 0.641358209578626 0.751937211230113 GO:0019001 guanyl nucleotide binding 5/256 400/18639 0.0125 0.910107421875 0.645660655676781 0.75335138360159 GO:0032561 guanyl ribonucleotide binding 5/256 400/18639 0.0125 0.910107421875 0.645660655676781 0.75335138360159 GO:0003689 DNA clamp loader activity 2/256 160/18639 0.0125 0.910107421875 0.648104266769414 0.75335138360159 GO:0099106 ion channel regulator activity 2/256 160/18639 0.0125 0.910107421875 0.648104266769414 0.75335138360159 GO:0005539 glycosaminoglycan binding 3/256 242/18639 0.012396694214876 0.902585872933884 0.648862426447808 0.75335138360159 GO:0098631 cell adhesion mediator activity 1/256 76/18639 0.0131578947368421 0.9580078125 0.651181179616407 0.75335138360159 GO:0140034 methylation-dependent protein binding 1/256 76/18639 0.0131578947368421 0.9580078125 0.651181179616407 0.75335138360159 GO:0008083 growth factor activity 2/256 162/18639 0.0123456790123457 0.898871527777778 0.654800210707863 0.756058226046669 GO:0003724 RNA helicase activity 1/256 77/18639 0.012987012987013 0.945566152597403 0.655991696128727 0.756058226046669 GO:0140713 histone chaperone activity 2/256 164/18639 0.0121951219512195 0.887909679878049 0.661394486196314 0.757769441021454 GO:0015103 inorganic anion transmembrane transporter activity 2/256 165/18639 0.0121212121212121 0.882528409090909 0.664653665287216 0.757769441021454 GO:0008186 ATP-dependent activity, acting on RNA 1/256 79/18639 0.0126582278481013 0.921627768987342 0.665415376579605 0.757769441021454 GO:0016835 carbon-oxygen lyase activity 1/256 79/18639 0.0126582278481013 0.921627768987342 0.665415376579605 0.757769441021454 GO:0033293 monocarboxylic acid binding 1/256 79/18639 0.0126582278481013 0.921627768987342 0.665415376579605 0.757769441021454 GO:0042277 peptide binding 3/256 249/18639 0.0120481927710843 0.877211972891566 0.667785868201176 0.757769441021454 GO:0140104 molecular carrier activity 3/256 249/18639 0.0120481927710843 0.877211972891566 0.667785868201176 0.757769441021454 GO:0003924 GTPase activity 4/256 331/18639 0.0120845921450151 0.879862160120846 0.669503946120643 0.757769441021454 GO:0000049 tRNA binding 1/256 80/18639 0.0125 0.910107421875 0.670030336902645 0.757769441021454 GO:0001216 DNA-binding transcription activator activity 6/256 491/18639 0.0122199592668024 0.889718049898167 0.670206446953203 0.757769441021454 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/256 167/18639 0.0119760479041916 0.871959206586826 0.671096465741223 0.757769441021454 GO:0016247 channel regulator activity 2/256 168/18639 0.0119047619047619 0.866768973214286 0.6742802392542 0.758904623814336 GO:0030971 receptor tyrosine kinase binding 1/256 81/18639 0.0123456790123457 0.898871527777778 0.674581887834965 0.758904623814336 GO:0140097 catalytic activity, acting on DNA 4/256 336/18639 0.0119047619047619 0.866768973214286 0.680895057853461 0.764601422763887 GO:0030165 PDZ domain binding 1/256 83/18639 0.0120481927710843 0.877211972891566 0.683498221186745 0.766118885286241 GO:0008201 heparin binding 2/256 172/18639 0.0116279069767442 0.846611555232558 0.686766384811336 0.766799997919267 GO:0004527 exonuclease activity 1/256 84/18639 0.0119047619047619 0.866768973214286 0.687864704015813 0.766799997919267 GO:0180051 translation factor activity 1/256 84/18639 0.0119047619047619 0.866768973214286 0.687864704015813 0.766799997919267 GO:0140030 modification-dependent protein binding 2/256 173/18639 0.0115606936416185 0.841717846820809 0.689826114865294 0.767588331450109 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/256 86/18639 0.0116279069767442 0.846611555232558 0.696418466416248 0.773517425493183 GO:0003730 mRNA 3'-UTR binding 3/256 262/18639 0.0114503816793893 0.833686187977099 0.70093794071242 0.777126847311596 GO:0003727 single-stranded RNA binding 1/256 89/18639 0.0112359550561798 0.818074087078652 0.708813257234592 0.78347218856212 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/256 349/18639 0.0114613180515759 0.834482449856733 0.709221556312769 0.78347218856212 GO:0016757 glycosyltransferase activity 3/256 267/18639 0.0112359550561798 0.818074087078652 0.713003156252882 0.78623050743561 GO:0008514 organic anion transmembrane transporter activity 3/256 269/18639 0.0111524163568773 0.811991751858736 0.717723524842693 0.790012225186561 GO:0052689 carboxylic ester hydrolase activity 1/256 92/18639 0.0108695652173913 0.791397758152174 0.720703882988934 0.791868539298434 GO:0015276 ligand-gated monoatomic ion channel activity 2/256 186/18639 0.010752688172043 0.78288810483871 0.727405386129168 0.795994519618911 GO:0016410 N-acyltransferase activity 1/256 94/18639 0.0106382978723404 0.774559507978723 0.728360998344102 0.795994519618911 GO:0042562 hormone binding 1/256 94/18639 0.0106382978723404 0.774559507978723 0.728360998344102 0.795994519618911 GO:0008276 protein methyltransferase activity 1/256 95/18639 0.0105263157894737 0.76640625 0.732110773724199 0.796614263671509 GO:0022834 ligand-gated channel activity 2/256 188/18639 0.0106382978723404 0.774559507978723 0.732833056286045 0.796614263671509 GO:0140597 protein carrier chaperone 2/256 188/18639 0.0106382978723404 0.774559507978723 0.732833056286045 0.796614263671509 GO:0030594 neurotransmitter receptor activity 1/256 97/18639 0.0103092783505155 0.75060405927835 0.739456340428003 0.801693068213828 GO:0005216 monoatomic ion channel activity 5/256 448/18639 0.0111607142857143 0.812595912388393 0.740125136504596 0.801693068213828 GO:0008170 N-methyltransferase activity 1/256 98/18639 0.0102040816326531 0.742944834183673 0.743053534735544 0.802026037492334 GO:0042626 ATPase-coupled transmembrane transporter activity 1/256 98/18639 0.0102040816326531 0.742944834183673 0.743053534735544 0.802026037492334 GO:0015291 secondary active transmembrane transporter activity 3/256 287/18639 0.0104529616724739 0.76106543989547 0.757535595821998 0.816217930709618 GO:0005253 monoatomic anion channel activity 1/256 103/18639 0.00970873786407767 0.706879550970874 0.760310824496981 0.817768408773554 GO:0003714 transcription corepressor activity 2/256 204/18639 0.00980392156862745 0.713809742647059 0.773031258600423 0.828537881372082 GO:0008168 methyltransferase activity 2/256 204/18639 0.00980392156862745 0.713809742647059 0.773031258600423 0.828537881372082 GO:0005496 steroid binding 1/256 108/18639 0.00925925925925926 0.674153645833333 0.776413286221845 0.830707921621974 GO:0004518 nuclease activity 2/256 209/18639 0.00956937799043062 0.696732954545454 0.784468360378619 0.837861494854651 GO:0043022 ribosome binding 1/256 112/18639 0.00892857142857143 0.650076729910714 0.78851569562132 0.840717083136321 GO:0001221 transcription coregulator binding 1/256 115/18639 0.00869565217391304 0.633118206521739 0.797162240878293 0.846354387409702 GO:0016741 transferase activity, transferring one-carbon groups 2/256 215/18639 0.00930232558139535 0.677289244186047 0.79752420390378 0.846354387409702 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/256 484/18639 0.0103305785123967 0.75215489411157 0.797951767214703 0.846354387409702 GO:0015294 solute:monoatomic cation symporter activity 1/256 116/18639 0.00862068965517241 0.627660290948276 0.799965440313359 0.847022230920027 GO:0140297 DNA-binding transcription factor binding 5/256 488/18639 0.0102459016393443 0.745989690061475 0.803707874088709 0.849515058622263 GO:0004540 RNA nuclease activity 1/256 121/18639 0.00826446280991736 0.601723915289256 0.813413053097632 0.856813749562394 GO:0015108 chloride transmembrane transporter activity 1/256 121/18639 0.00826446280991736 0.601723915289256 0.813413053097632 0.856813749562394 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/256 229/18639 0.00873362445414847 0.635882914847162 0.825305041967486 0.867846538976119 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/256 128/18639 0.0078125 0.568817138671875 0.830740067398856 0.872063329756603 GO:0005262 calcium channel activity 1/256 131/18639 0.00763358778625954 0.555790791984733 0.83766616601762 0.87782824247052 GO:0015297 antiporter activity 1/256 135/18639 0.00740740740740741 0.539322916666667 0.846463743315881 0.885531300699691 GO:0099094 ligand-gated monoatomic cation channel activity 1/256 136/18639 0.00735294117647059 0.535357306985294 0.848587893862311 0.886238551269171 GO:0005261 monoatomic cation channel activity 3/256 341/18639 0.00879765395894428 0.640544813049853 0.850402267527072 0.886620422021411 GO:0140101 catalytic activity, acting on a tRNA 1/256 139/18639 0.00719424460431655 0.523802832733813 0.854786303024945 0.889409593019108 GO:0042393 histone binding 2/256 247/18639 0.00809716599190283 0.589543269230769 0.855984069098456 0.889409593019108 GO:0008194 UDP-glycosyltransferase activity 1/256 145/18639 0.00689655172413793 0.502128232758621 0.866435005341683 0.898475520435497 GO:0015293 symporter activity 1/256 146/18639 0.00684931506849315 0.498688998287671 0.868283855705721 0.898475520435497 GO:0046873 metal ion transmembrane transporter activity 4/256 450/18639 0.00888888888888889 0.6471875 0.869113575323226 0.898475520435497 GO:0019842 vitamin binding 1/256 150/18639 0.00666666666666667 0.485390625 0.875427797015572 0.903476916987403 GO:0004386 helicase activity 1/256 155/18639 0.00645161290322581 0.469732862903226 0.883817319030823 0.910599662031757 GO:0015079 potassium ion transmembrane transporter activity 1/256 160/18639 0.00625 0.4550537109375 0.891643892903585 0.917119432700831 GO:0004866 endopeptidase inhibitor activity 1/256 161/18639 0.0062111801242236 0.452227290372671 0.893145011114348 0.917122058392585 GO:0015081 sodium ion transmembrane transporter activity 1/256 164/18639 0.00609756097560976 0.443954839939024 0.897525206605821 0.920076091193907 GO:0015631 tubulin binding 3/256 385/18639 0.00779220779220779 0.567339691558442 0.901578363490327 0.920985284240372 GO:0005201 extracellular matrix structural constituent 1/256 168/18639 0.00595238095238095 0.433384486607143 0.90308847573263 0.920985284240372 GO:0140098 catalytic activity, acting on RNA 3/256 387/18639 0.00775193798449612 0.564407703488372 0.903479048945514 0.920985284240372 GO:0030414 peptidase inhibitor activity 1/256 169/18639 0.00591715976331361 0.430820081360947 0.904431627170692 0.920985284240372 GO:0016755 aminoacyltransferase activity 4/256 496/18639 0.00806451612903226 0.587166078629032 0.912364564336276 0.92752012188339 GO:0043021 ribonucleoprotein complex binding 1/256 177/18639 0.00564971751412429 0.411347987288136 0.914530250726392 0.928179955961114 GO:0008234 cysteine-type peptidase activity 1/256 187/18639 0.0053475935828877 0.389350768716578 0.925671484750469 0.937932034217363 GO:0022836 gated channel activity 2/256 318/18639 0.00628930817610063 0.457915683962264 0.934788358607185 0.945604091681979 GO:0004842 ubiquitin-protein transferase activity 3/256 449/18639 0.0066815144766147 0.486471673162584 0.948194164402543 0.957582225436232 GO:0061630 ubiquitin protein ligase activity 2/256 353/18639 0.0056657223796034 0.412513279036827 0.956509882246409 0.964388876334106 GO:0019787 ubiquitin-like protein transferase activity 3/256 479/18639 0.00626304801670146 0.45600371868476 0.962086206577563 0.96841572109452 GO:0061659 ubiquitin-like protein ligase activity 2/256 372/18639 0.00537634408602151 0.391444052419355 0.965210843805357 0.969965577026073 GO:0003712 transcription coregulator activity 3/256 495/18639 0.00606060606060606 0.441264204545455 0.9679856468772 0.971159370309585 GO:0003713 transcription coactivator activity 1/256 256/18639 0.00390625 0.284408569335938 0.971704462577905 0.973294813580488 GO:0008017 microtubule binding 1/256 276/18639 0.0036231884057971 0.263799252717391 0.978627985476114 0.978627985476114