ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 107/2088 175/18639 0.611428571428571 5.45805418719212 2.91771514552082e-57 3.54210618666228e-54 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 37/2088 68/18639 0.544117647058823 4.85718813387424 3.25985258992909e-18 1.97873052208696e-15 GO:0015078 proton transmembrane transporter activity 64/2088 185/18639 0.345945945945946 3.08816402609506 2.5785841449642e-17 1.04346705066218e-14 GO:0009055 electron transfer activity 47/2088 116/18639 0.405172413793103 3.61686236623068 3.92461680943083e-16 1.19112120166226e-13 GO:0008137 NADH dehydrogenase (ubiquinone) activity 26/2088 41/18639 0.634146341463415 5.66084945332212 1.94880775216924e-15 4.73170522226692e-13 GO:0003954 NADH dehydrogenase activity 26/2088 44/18639 0.590909090909091 5.27488244514107 2.2564514457976e-14 4.56555342533049e-12 GO:0022853 active monoatomic ion transmembrane transporter activity 43/2088 118/18639 0.364406779661017 3.25295879602572 5.57912444006994e-13 9.67579581463557e-11 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 28/2088 58/18639 0.482758620689655 4.30945303210464 2.01171919564067e-12 3.05278387938471e-10 GO:0019843 rRNA binding 28/2088 65/18639 0.430769230769231 3.84535809018568 6.18552265093474e-11 8.34358277581641e-09 GO:0016651 oxidoreductase activity, acting on NAD(P)H 32/2088 88/18639 0.363636363636364 3.24608150470219 5.38997323713293e-10 6.54342750987938e-08 GO:0015399 primary active transmembrane transporter activity 46/2088 166/18639 0.27710843373494 2.47367054424595 3.49418864600097e-09 3.85631365113198e-07 GO:0045296 cadherin binding 67/2088 334/18639 0.20059880239521 1.79069017138137 1.42522758532596e-06 0.00014418552404881 GO:0003743 translation initiation factor activity 18/2088 51/18639 0.352941176470588 3.15060851926978 5.22996842985754e-06 0.000488398590295927 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 10/2088 18/18639 0.555555555555556 4.95929118773946 5.69618754973656e-06 0.000493940834670013 GO:0008135 translation factor activity, RNA binding 24/2088 83/18639 0.289156626506024 2.58122143747403 8.4228758522192e-06 0.000681691418972941 GO:0180051 translation factor activity 24/2088 84/18639 0.285714285714286 2.55049261083744 1.0551727787613e-05 0.000800612345885138 GO:0098641 cadherin binding involved in cell-cell adhesion 9/2088 18/18639 0.5 4.46336206896552 5.15445527132601e-05 0.00368088747022928 GO:0004129 cytochrome-c oxidase activity 8/2088 15/18639 0.533333333333333 4.76091954022988 7.61171924503892e-05 0.00513368175748736 GO:0016675 oxidoreductase activity, acting on a heme group of donors 8/2088 16/18639 0.5 4.46336206896552 0.000137275549779069 0.00877118512798896 GO:0016783 sulfurtransferase activity 6/2088 10/18639 0.6 5.35603448275862 0.000276060326912353 0.0167568618435798 GO:0005484 SNAP receptor activity 12/2088 36/18639 0.333333333333333 2.97557471264368 0.00035906652275361 0.0207574646963277 GO:0015252 proton channel activity 10/2088 27/18639 0.37037037037037 3.30619412515964 0.000424570672988291 0.023428581682172 GO:1990948 ubiquitin ligase inhibitor activity 6/2088 11/18639 0.545454545454545 4.86912225705329 0.000549683370982809 0.028965235826075 GO:0031386 protein tag activity 7/2088 15/18639 0.466666666666667 4.16580459770115 0.000623456571061319 0.028965235826075 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/2088 15/18639 0.466666666666667 4.16580459770115 0.000623456571061319 0.028965235826075 GO:0141047 molecular tag activity 7/2088 15/18639 0.466666666666667 4.16580459770115 0.000623456571061319 0.028965235826075 GO:0051287 NAD binding 15/2088 54/18639 0.277777777777778 2.47964559386973 0.000644202114747962 0.028965235826075 GO:0048027 mRNA 5'-UTR binding 9/2088 24/18639 0.375 3.34752155172414 0.00074126494610077 0.0321391301630834 GO:0010314 phosphatidylinositol-5-phosphate binding 8/2088 21/18639 0.380952380952381 3.40065681444992 0.00129737992263373 0.0543110077957708 GO:0032266 phosphatidylinositol-3-phosphate binding 13/2088 48/18639 0.270833333333333 2.41765445402299 0.00186759823354777 0.0755754751842331 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 25/2088 122/18639 0.204918032786885 1.82924674957603 0.00197861781191656 0.0774852265698935 GO:0033204 ribonuclease P RNA binding 5/2088 10/18639 0.5 4.46336206896552 0.00272316723425201 0.103310156949436 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 26/2088 132/18639 0.196969696969697 1.75829414838036 0.00290490532442139 0.106865304965078 GO:0140101 catalytic activity, acting on a tRNA 27/2088 139/18639 0.194244604316547 1.73396799801538 0.00299735402625728 0.107023170231657 GO:0120227 acyl-CoA binding 7/2088 19/18639 0.368421052631579 3.28879310344828 0.00325969608551107 0.113064887080298 GO:0022804 active transmembrane transporter activity 70/2088 457/18639 0.153172866520788 1.3673319248472 0.00408611018120567 0.137792715555102 GO:0030742 GTP-dependent protein binding 7/2088 20/18639 0.35 3.12435344827586 0.00453574448446078 0.148821454165821 GO:0031593 polyubiquitin modification-dependent protein binding 14/2088 59/18639 0.23728813559322 2.11820572764465 0.00480395626168469 0.153473760570663 GO:0016829 lyase activity 35/2088 200/18639 0.175 1.56217672413793 0.0049539184691839 0.15420659029716 GO:0016853 isomerase activity 32/2088 180/18639 0.177777777777778 1.58697318007663 0.00550896694235013 0.161936132572376 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 14/2088 60/18639 0.233333333333333 2.08290229885057 0.00563398455706143 0.161936132572376 GO:0017069 snRNA binding 13/2088 54/18639 0.240740740740741 2.14902618135377 0.00567645912433299 0.161936132572376 GO:0140098 catalytic activity, acting on RNA 60/2088 387/18639 0.155038759689922 1.38398823843892 0.00573579382258004 0.161936132572376 GO:0043022 ribosome binding 22/2088 112/18639 0.196428571428571 1.75346366995074 0.00604813735821578 0.166873608019863 GO:0098632 cell-cell adhesion mediator activity 13/2088 55/18639 0.236363636363636 2.10995297805643 0.00668790139892269 0.180424717739825 GO:0004526 ribonuclease P activity 5/2088 12/18639 0.416666666666667 3.7194683908046 0.0070623647398665 0.186385017265172 GO:0003713 transcription coactivator activity 42/2088 256/18639 0.1640625 1.46454067887931 0.00727915955053047 0.188019142432851 GO:0043021 ribonucleoprotein complex binding 31/2088 177/18639 0.175141242937853 1.56343756088058 0.0077422369459298 0.195814076090808 GO:0004549 tRNA-specific ribonuclease activity 6/2088 17/18639 0.352941176470588 3.15060851926978 0.00813757482740195 0.201612568172775 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 9/2088 33/18639 0.272727272727273 2.43456112852665 0.00864104940491972 0.209804679551451 GO:0098631 cell adhesion mediator activity 16/2088 76/18639 0.210526315789474 1.87931034482759 0.0091494646875285 0.217793139816855 GO:0016830 carbon-carbon lyase activity 12/2088 51/18639 0.235294117647059 2.10040567951318 0.00933071049153502 0.217836202629298 GO:0051540 metal cluster binding 16/2088 77/18639 0.207792207792208 1.85490371697268 0.0103797843798371 0.234487810484112 GO:0019104 DNA N-glycosylase activity 5/2088 13/18639 0.384615384615385 3.43335543766578 0.0104302650462455 0.234487810484112 GO:0005346 purine ribonucleotide transmembrane transporter activity 6/2088 19/18639 0.315789473684211 2.81896551724138 0.0146718100088749 0.308753088915465 GO:0097001 ceramide binding 6/2088 19/18639 0.315789473684211 2.81896551724138 0.0146718100088749 0.308753088915465 GO:0005347 ATP transmembrane transporter activity 5/2088 14/18639 0.357142857142857 3.1881157635468 0.0147509712990914 0.308753088915465 GO:0071933 Arp2/3 complex binding 5/2088 14/18639 0.357142857142857 3.1881157635468 0.0147509712990914 0.308753088915465 GO:0055106 ubiquitin-protein transferase regulator activity 9/2088 36/18639 0.25 2.23168103448276 0.0155273288707615 0.319494529645838 GO:0019213 deacetylase activity 9/2088 37/18639 0.243243243243243 2.17136533084809 0.0185333804184865 0.373982878103789 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 6/2088 20/18639 0.3 2.67801724137931 0.0190158380907666 0.373982878103789 GO:0016874 ligase activity 28/2088 167/18639 0.167664670658683 1.49669626264712 0.0190996198043121 0.373982878103789 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 5/2088 15/18639 0.333333333333333 2.97557471264368 0.0201234476463885 0.376649162500448 GO:0017081 chloride channel regulator activity 5/2088 15/18639 0.333333333333333 2.97557471264368 0.0201234476463885 0.376649162500448 GO:0051536 iron-sulfur cluster binding 15/2088 76/18639 0.197368421052632 1.76185344827586 0.020166553181655 0.376649162500448 GO:0050681 nuclear androgen receptor binding 7/2088 26/18639 0.269230769230769 2.40334880636605 0.021172136432551 0.38943899438056 GO:0031369 translation initiation factor binding 8/2088 32/18639 0.25 2.23168103448276 0.0219778741330999 0.398225958172885 GO:0140297 DNA-binding transcription factor binding 69/2088 488/18639 0.141393442622951 1.26218025720746 0.024782112361904 0.438905131323057 GO:0004519 endonuclease activity 22/2088 127/18639 0.173228346456693 1.54636166168884 0.024946008287719 0.438905131323057 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 9/2088 39/18639 0.230769230769231 2.06001326259947 0.0257728622524585 0.439156959083243 GO:0160215 deacylase activity 13/2088 65/18639 0.2 1.78534482758621 0.0264759368894257 0.439156959083243 GO:0000062 fatty-acyl-CoA binding 5/2088 16/18639 0.3125 2.78960129310345 0.0266301641456738 0.439156959083243 GO:0005080 protein kinase C binding 11/2088 52/18639 0.211538461538462 1.88834549071618 0.0269878141477138 0.439156959083243 GO:0015217 ADP transmembrane transporter activity 4/2088 11/18639 0.363636363636364 3.24608150470219 0.0271307841278774 0.439156959083243 GO:0034511 U3 snoRNA binding 4/2088 11/18639 0.363636363636364 3.24608150470219 0.0271307841278774 0.439156959083243 GO:0034062 5'-3' RNA polymerase activity 6/2088 22/18639 0.272727272727273 2.43456112852665 0.0301571257909881 0.452179450770946 GO:0097747 RNA polymerase activity 6/2088 22/18639 0.272727272727273 2.43456112852665 0.0301571257909881 0.452179450770946 GO:0016860 intramolecular oxidoreductase activity 11/2088 53/18639 0.207547169811321 1.85271633051399 0.03072487402067 0.452179450770946 GO:0034212 protein N-acetyltransferase activity 11/2088 53/18639 0.207547169811321 1.85271633051399 0.03072487402067 0.452179450770946 GO:0008175 tRNA methyltransferase activity 8/2088 34/18639 0.235294117647059 2.10040567951318 0.0310569060704015 0.452179450770946 GO:0016410 N-acyltransferase activity 17/2088 94/18639 0.180851063829787 1.61440755685987 0.0310924672002853 0.452179450770946 GO:0016866 intramolecular transferase activity 7/2088 28/18639 0.25 2.23168103448276 0.0312875402510374 0.452179450770946 GO:0046966 nuclear thyroid hormone receptor binding 7/2088 28/18639 0.25 2.23168103448276 0.0312875402510374 0.452179450770946 GO:0051537 2 iron, 2 sulfur cluster binding 7/2088 28/18639 0.25 2.23168103448276 0.0312875402510374 0.452179450770946 GO:0008173 RNA methyltransferase activity 13/2088 67/18639 0.194029850746269 1.73205095213587 0.0332086385089673 0.468350419883977 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 13/2088 67/18639 0.194029850746269 1.73205095213587 0.0332086385089673 0.468350419883977 GO:0004550 nucleoside diphosphate kinase activity 5/2088 17/18639 0.294117647058824 2.62550709939148 0.0343354096949538 0.468350419883977 GO:0008429 phosphatidylethanolamine binding 5/2088 17/18639 0.294117647058824 2.62550709939148 0.0343354096949538 0.468350419883977 GO:1901567 fatty acid derivative binding 5/2088 17/18639 0.294117647058824 2.62550709939148 0.0343354096949538 0.468350419883977 GO:0000295 adenine nucleotide transmembrane transporter activity 6/2088 23/18639 0.260869565217391 2.32871064467766 0.0370499427343079 0.470775962461425 GO:0017134 fibroblast growth factor binding 6/2088 23/18639 0.260869565217391 2.32871064467766 0.0370499427343079 0.470775962461425 GO:0004859 phospholipase inhibitor activity 4/2088 12/18639 0.333333333333333 2.97557471264368 0.0371649938218828 0.470775962461425 GO:0016208 AMP binding 4/2088 12/18639 0.333333333333333 2.97557471264368 0.0371649938218828 0.470775962461425 GO:0017166 vinculin binding 4/2088 12/18639 0.333333333333333 2.97557471264368 0.0371649938218828 0.470775962461425 GO:0097371 MDM2/MDM4 family protein binding 4/2088 12/18639 0.333333333333333 2.97557471264368 0.0371649938218828 0.470775962461425 GO:0016407 acetyltransferase activity 17/2088 96/18639 0.177083333333333 1.58077406609195 0.0372277532094702 0.470775962461425 GO:1901981 phosphatidylinositol phosphate binding 29/2088 185/18639 0.156756756756757 1.39932432432432 0.0388471767081697 0.486190438388846 GO:0008080 N-acetyltransferase activity 13/2088 69/18639 0.188405797101449 1.68184657671164 0.0410913147511168 0.509029143957712 GO:0004706 JUN kinase kinase kinase activity 5/2088 18/18639 0.277777777777778 2.47964559386973 0.0432844193624777 0.528807817917835 GO:0003712 transcription coregulator activity 68/2088 495/18639 0.137373737373737 1.22629745733194 0.0437990552788882 0.528807817917835 GO:0042625 ATPase-coupled ion transmembrane transporter activity 6/2088 24/18639 0.25 2.23168103448276 0.0448724079161096 0.528807817917835 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 6/2088 24/18639 0.25 2.23168103448276 0.0448724079161096 0.528807817917835 GO:0046961 proton-transporting ATPase activity, rotational mechanism 6/2088 24/18639 0.25 2.23168103448276 0.0448724079161096 0.528807817917835 GO:0004860 protein kinase inhibitor activity 15/2088 84/18639 0.178571428571429 1.5940578817734 0.0453014934624834 0.528807817917835 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 4/2088 13/18639 0.307692307692308 2.74668435013263 0.0490470954999439 0.551325684601221 GO:0009982 pseudouridine synthase activity 4/2088 13/18639 0.307692307692308 2.74668435013263 0.0490470954999439 0.551325684601221 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/2088 13/18639 0.307692307692308 2.74668435013263 0.0490470954999439 0.551325684601221 GO:0089720 caspase binding 4/2088 13/18639 0.307692307692308 2.74668435013263 0.0490470954999439 0.551325684601221 GO:0070273 phosphatidylinositol-4-phosphate binding 7/2088 31/18639 0.225806451612903 2.01571190211346 0.0517902597310395 0.571889715240599 GO:0043130 ubiquitin binding 17/2088 100/18639 0.17 1.51754310344828 0.0520557186101273 0.571889715240599 GO:0003924 GTPase activity 47/2088 331/18639 0.141993957703928 1.26754088967601 0.0522897515582426 0.571889715240599 GO:0004709 MAP kinase kinase kinase activity 6/2088 25/18639 0.24 2.14241379310345 0.0536482723277117 0.581508951837875 GO:0016835 carbon-oxygen lyase activity 14/2088 79/18639 0.177215189873418 1.58195111305107 0.0547779658610114 0.588499562435999 GO:0070063 RNA polymerase binding 11/2088 59/18639 0.186440677966102 1.66430450029223 0.0610474073731087 0.641306760823829 GO:0008494 translation activator activity 4/2088 14/18639 0.285714285714286 2.55049261083744 0.0627655451802851 0.641306760823829 GO:0016530 metallochaperone activity 4/2088 14/18639 0.285714285714286 2.55049261083744 0.0627655451802851 0.641306760823829 GO:0044548 S100 protein binding 4/2088 14/18639 0.285714285714286 2.55049261083744 0.0627655451802851 0.641306760823829 GO:0004857 enzyme inhibitor activity 57/2088 416/18639 0.137019230769231 1.22313287466844 0.0627998039475081 0.641306760823829 GO:0008157 protein phosphatase 1 binding 6/2088 26/18639 0.230769230769231 2.06001326259947 0.0633911130962599 0.641306760823829 GO:0015216 purine nucleotide transmembrane transporter activity 6/2088 26/18639 0.230769230769231 2.06001326259947 0.0633911130962599 0.641306760823829 GO:0043024 ribosomal small subunit binding 5/2088 20/18639 0.25 2.23168103448276 0.0649989985261924 0.648614290125029 GO:0030971 receptor tyrosine kinase binding 14/2088 81/18639 0.172839506172839 1.54289059174117 0.0652179668707996 0.648614290125029 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 9/2088 46/18639 0.195652173913043 1.74653298350825 0.0662875499752373 0.648614290125029 GO:0106310 protein serine kinase activity 50/2088 361/18639 0.138504155124654 1.23638838475499 0.0665274585545232 0.648614290125029 GO:0016251 RNA polymerase II general transcription initiation factor activity 10/2088 53/18639 0.188679245283019 1.68428757319453 0.0673191108366999 0.648614290125029 GO:1901505 carbohydrate derivative transmembrane transporter activity 10/2088 53/18639 0.188679245283019 1.68428757319453 0.0673191108366999 0.648614290125029 GO:0005525 GTP binding 52/2088 378/18639 0.137566137566138 1.22801496077358 0.0687173056926515 0.656872512684086 GO:0019003 GDP binding 13/2088 75/18639 0.173333333333333 1.54729885057471 0.0723808050854812 0.683007635476037 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 8/2088 40/18639 0.2 1.78534482758621 0.0725765938850155 0.683007635476037 GO:0005504 fatty acid binding 9/2088 47/18639 0.191489361702128 1.70937270726339 0.0742091280848977 0.683487110286838 GO:0061733 protein-lysine-acetyltransferase activity 9/2088 47/18639 0.191489361702128 1.70937270726339 0.0742091280848977 0.683487110286838 GO:0016836 hydro-lyase activity 11/2088 61/18639 0.180327868852459 1.60973713962691 0.0744213414943884 0.683487110286838 GO:0019210 kinase inhibitor activity 15/2088 90/18639 0.166666666666667 1.48778735632184 0.0748795598584427 0.683487110286838 GO:0004467 long-chain fatty acid-CoA ligase activity 4/2088 15/18639 0.266666666666667 2.38045977011494 0.0782717624653383 0.701529605162243 GO:0016846 carbon-sulfur lyase activity 4/2088 15/18639 0.266666666666667 2.38045977011494 0.0782717624653383 0.701529605162243 GO:0016831 carboxy-lyase activity 7/2088 34/18639 0.205882352941176 1.83785496957404 0.0791676737291823 0.701529605162243 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 7/2088 34/18639 0.205882352941176 1.83785496957404 0.0791676737291823 0.701529605162243 GO:0051082 unfolded protein binding 19/2088 121/18639 0.15702479338843 1.40171701339413 0.0808818109242862 0.711525496102054 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 9/2088 48/18639 0.1875 1.67376077586207 0.0826881318861834 0.722182677049113 GO:0019001 guanyl nucleotide binding 54/2088 400/18639 0.135 1.20510775862069 0.0843585052908885 0.723187514429308 GO:0032561 guanyl ribonucleotide binding 54/2088 400/18639 0.135 1.20510775862069 0.0843585052908885 0.723187514429308 GO:0003724 RNA helicase activity 13/2088 77/18639 0.168831168831169 1.5071092700403 0.0855340456899902 0.723187514429308 GO:0046625 sphingolipid binding 6/2088 28/18639 0.214285714285714 1.91286945812808 0.0857817150558651 0.723187514429308 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 6/2088 28/18639 0.214285714285714 1.91286945812808 0.0857817150558651 0.723187514429308 GO:0004520 DNA endonuclease activity 8/2088 42/18639 0.19047619047619 1.70032840722496 0.0915373155830258 0.727846136508478 GO:0051879 Hsp90 protein binding 8/2088 42/18639 0.19047619047619 1.70032840722496 0.0915373155830258 0.727846136508478 GO:0004407 histone deacetylase activity 5/2088 22/18639 0.227272727272727 2.02880094043887 0.0917622976747067 0.727846136508478 GO:0033558 protein lysine deacetylase activity 5/2088 22/18639 0.227272727272727 2.02880094043887 0.0917622976747067 0.727846136508478 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 3/2088 10/18639 0.3 2.67801724137931 0.0923297405455565 0.727846136508478 GO:0031434 mitogen-activated protein kinase kinase binding 3/2088 10/18639 0.3 2.67801724137931 0.0923297405455565 0.727846136508478 GO:0031996 thioesterase binding 3/2088 10/18639 0.3 2.67801724137931 0.0923297405455565 0.727846136508478 GO:0047429 nucleoside triphosphate diphosphatase activity 3/2088 10/18639 0.3 2.67801724137931 0.0923297405455565 0.727846136508478 GO:0070513 death domain binding 3/2088 10/18639 0.3 2.67801724137931 0.0923297405455565 0.727846136508478 GO:0097177 mitochondrial ribosome binding 3/2088 10/18639 0.3 2.67801724137931 0.0923297405455565 0.727846136508478 GO:0017070 U6 snRNA binding 4/2088 16/18639 0.25 2.23168103448276 0.095485628571893 0.733668057508089 GO:0030275 LRR domain binding 4/2088 16/18639 0.25 2.23168103448276 0.095485628571893 0.733668057508089 GO:0043023 ribosomal large subunit binding 4/2088 16/18639 0.25 2.23168103448276 0.095485628571893 0.733668057508089 GO:0055102 lipase inhibitor activity 4/2088 16/18639 0.25 2.23168103448276 0.095485628571893 0.733668057508089 GO:0008186 ATP-dependent activity, acting on RNA 13/2088 79/18639 0.164556962025316 1.46895460497599 0.100095657052692 0.764252375232507 GO:0008200 ion channel inhibitor activity 8/2088 43/18639 0.186046511627907 1.6607858861267 0.101987813630755 0.769026122656751 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 8/2088 43/18639 0.186046511627907 1.6607858861267 0.101987813630755 0.769026122656751 GO:0008171 O-methyltransferase activity 5/2088 23/18639 0.217391304347826 1.94059220389805 0.10696017404704 0.781804552009887 GO:0140102 catalytic activity, acting on a rRNA 5/2088 23/18639 0.217391304347826 1.94059220389805 0.10696017404704 0.781804552009887 GO:0140103 catalytic activity, acting on a glycoprotein 5/2088 23/18639 0.217391304347826 1.94059220389805 0.10696017404704 0.781804552009887 GO:0000049 tRNA binding 13/2088 80/18639 0.1625 1.45059267241379 0.107905589993725 0.781804552009887 GO:0008106 alcohol dehydrogenase (NADP+) activity 6/2088 30/18639 0.2 1.78534482758621 0.111956385640451 0.781804552009887 GO:0015215 nucleotide transmembrane transporter activity 6/2088 30/18639 0.2 1.78534482758621 0.111956385640451 0.781804552009887 GO:0051721 protein phosphatase 2A binding 6/2088 30/18639 0.2 1.78534482758621 0.111956385640451 0.781804552009887 GO:1902936 phosphatidylinositol bisphosphate binding 17/2088 111/18639 0.153153153153153 1.3671559490525 0.112665102831077 0.781804552009887 GO:0016248 channel inhibitor activity 8/2088 44/18639 0.181818181818182 1.6230407523511 0.113074155836249 0.781804552009887 GO:0016790 thiolester hydrolase activity 8/2088 44/18639 0.181818181818182 1.6230407523511 0.113074155836249 0.781804552009887 GO:0022829 wide pore channel activity 7/2088 37/18639 0.189189189189189 1.68883970177074 0.113503855127267 0.781804552009887 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/2088 17/18639 0.235294117647059 2.10040567951318 0.114301080534028 0.781804552009887 GO:0004659 prenyltransferase activity 4/2088 17/18639 0.235294117647059 2.10040567951318 0.114301080534028 0.781804552009887 GO:0070403 NAD+ binding 4/2088 17/18639 0.235294117647059 2.10040567951318 0.114301080534028 0.781804552009887 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 3/2088 11/18639 0.272727272727273 2.43456112852665 0.116779349202186 0.781804552009887 GO:0019107 myristoyltransferase activity 3/2088 11/18639 0.272727272727273 2.43456112852665 0.116779349202186 0.781804552009887 GO:0032050 clathrin heavy chain binding 3/2088 11/18639 0.272727272727273 2.43456112852665 0.116779349202186 0.781804552009887 GO:0043522 leucine zipper domain binding 3/2088 11/18639 0.272727272727273 2.43456112852665 0.116779349202186 0.781804552009887 GO:0045294 alpha-catenin binding 3/2088 11/18639 0.272727272727273 2.43456112852665 0.116779349202186 0.781804552009887 GO:0070990 snRNP binding 3/2088 11/18639 0.272727272727273 2.43456112852665 0.116779349202186 0.781804552009887 GO:0019207 kinase regulator activity 39/2088 287/18639 0.13588850174216 1.21303916856903 0.117206283744481 0.781804552009887 GO:0001786 phosphatidylserine binding 10/2088 59/18639 0.169491525423729 1.51300409117475 0.118931718439683 0.788978722326641 GO:0016741 transferase activity, transferring one-carbon groups 30/2088 215/18639 0.13953488372093 1.24558941459503 0.12114350608352 0.797184510125073 GO:0032182 ubiquitin-like protein binding 18/2088 120/18639 0.15 1.33900862068966 0.121481988775238 0.797184510125073 GO:0141110 transporter inhibitor activity 8/2088 45/18639 0.177777777777778 1.58697318007663 0.124783204951521 0.799510132103351 GO:0001098 basal transcription machinery binding 10/2088 60/18639 0.166666666666667 1.48778735632184 0.129213816407612 0.799510132103351 GO:0001099 basal RNA polymerase II transcription machinery binding 10/2088 60/18639 0.166666666666667 1.48778735632184 0.129213816407612 0.799510132103351 GO:0035591 signaling adaptor activity 19/2088 129/18639 0.147286821705426 1.31478882651697 0.129841481340158 0.799510132103351 GO:0016922 nuclear receptor binding 20/2088 137/18639 0.145985401459854 1.30317140699723 0.130830558223381 0.799510132103351 GO:0000149 SNARE binding 16/2088 106/18639 0.150943396226415 1.34743005855563 0.132792566850519 0.799510132103351 GO:0005544 calcium-dependent phospholipid binding 9/2088 53/18639 0.169811320754717 1.51585881587508 0.133358034856008 0.799510132103351 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/2088 18/18639 0.222222222222222 1.98371647509579 0.134591555154471 0.799510132103351 GO:0070628 proteasome binding 4/2088 18/18639 0.222222222222222 1.98371647509579 0.134591555154471 0.799510132103351 GO:1990381 ubiquitin-specific protease binding 4/2088 18/18639 0.222222222222222 1.98371647509579 0.134591555154471 0.799510132103351 GO:0140223 general transcription initiation factor activity 11/2088 68/18639 0.161764705882353 1.44402890466531 0.134769797580716 0.799510132103351 GO:0072341 modified amino acid binding 14/2088 91/18639 0.153846153846154 1.37334217506631 0.136475638439437 0.799510132103351 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 19/2088 130/18639 0.146153846153846 1.304675066313 0.13697332591165 0.799510132103351 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 10/2088 61/18639 0.163934426229508 1.46339739966083 0.139957438939617 0.799510132103351 GO:0016776 phosphotransferase activity, phosphate group as acceptor 7/2088 39/18639 0.179487179487179 1.60223253757737 0.14008265517619 0.799510132103351 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 33/2088 243/18639 0.135802469135802 1.2122711792252 0.140580333257763 0.799510132103351 GO:0015645 fatty acid ligase activity 5/2088 25/18639 0.2 1.78534482758621 0.140711756756783 0.799510132103351 GO:0017025 TBP-class protein binding 5/2088 25/18639 0.2 1.78534482758621 0.140711756756783 0.799510132103351 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/2088 25/18639 0.2 1.78534482758621 0.140711756756783 0.799510132103351 GO:0120515 fatty acid-CoA ligase activity 5/2088 25/18639 0.2 1.78534482758621 0.140711756756783 0.799510132103351 GO:0030515 snoRNA binding 6/2088 32/18639 0.1875 1.67376077586207 0.141686685434151 0.799510132103351 GO:0051059 NF-kappaB binding 6/2088 32/18639 0.1875 1.67376077586207 0.141686685434151 0.799510132103351 GO:0004300 enoyl-CoA hydratase activity 3/2088 12/18639 0.25 2.23168103448276 0.143317467662287 0.799510132103351 GO:0005078 MAP-kinase scaffold activity 3/2088 12/18639 0.25 2.23168103448276 0.143317467662287 0.799510132103351 GO:0016423 tRNA (guanine) methyltransferase activity 3/2088 12/18639 0.25 2.23168103448276 0.143317467662287 0.799510132103351 GO:0034452 dynactin binding 3/2088 12/18639 0.25 2.23168103448276 0.143317467662287 0.799510132103351 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/2088 12/18639 0.25 2.23168103448276 0.143317467662287 0.799510132103351 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 3/2088 12/18639 0.25 2.23168103448276 0.143317467662287 0.799510132103351 GO:0004676 3-phosphoinositide-dependent protein kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0004711 ribosomal protein S6 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0035175 histone H3S10 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0035979 histone H2AXS139 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0044022 histone H3S28 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0044023 histone H4S1 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0044024 histone H2AS1 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0044025 histone H2BS14 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0072354 histone H3T3 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0072371 histone H2AS121 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0072518 Rho-dependent protein serine/threonine kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0140823 histone H2BS36 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0140855 histone H3S57 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0140995 histone H2A kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0140997 histone H4 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0140998 histone H2B kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:1990244 histone H2AT120 kinase activity 33/2088 245/18639 0.13469387755102 1.20237508796622 0.151472265555001 0.799510132103351 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 31/2088 229/18639 0.135371179039301 1.20842117151031 0.153447079653241 0.804889252733493 GO:0004677 DNA-dependent protein kinase activity 33/2088 246/18639 0.134146341463415 1.1974873843566 0.157098104072161 0.804889252733493 GO:0140857 histone H3T45 kinase activity 33/2088 246/18639 0.134146341463415 1.1974873843566 0.157098104072161 0.804889252733493 GO:0140313 molecular sequestering activity 9/2088 55/18639 0.163636363636364 1.46073667711599 0.157318444872731 0.804889252733493 GO:0140311 protein sequestering activity 6/2088 33/18639 0.181818181818182 1.6230407523511 0.157780945379121 0.804889252733493 GO:0140416 transcription regulator inhibitor activity 6/2088 33/18639 0.181818181818182 1.6230407523511 0.157780945379121 0.804889252733493 GO:0140030 modification-dependent protein binding 24/2088 173/18639 0.138728323699422 1.23838947578234 0.158821583072881 0.804889252733493 GO:0008198 ferrous iron binding 5/2088 26/18639 0.192307692307692 1.71667771883289 0.159121433818812 0.804889252733493 GO:0051139 metal cation:proton antiporter activity 5/2088 26/18639 0.192307692307692 1.71667771883289 0.159121433818812 0.804889252733493 GO:0120014 phospholipid transfer activity 5/2088 26/18639 0.192307692307692 1.71667771883289 0.159121433818812 0.804889252733493 GO:0035402 histone H3T11 kinase activity 33/2088 247/18639 0.133603238866397 1.19263925729443 0.16284263956046 0.816904811679334 GO:0035403 histone H3T6 kinase activity 33/2088 247/18639 0.133603238866397 1.19263925729443 0.16284263956046 0.816904811679334 GO:0044389 ubiquitin-like protein ligase binding 42/2088 322/18639 0.130434782608696 1.16435532233883 0.166116825524159 0.829900519285306 GO:0004679 AMP-activated protein kinase activity 33/2088 248/18639 0.133064516129032 1.18783022803115 0.16870478731916 0.839086788366248 GO:0019212 phosphatase inhibitor activity 9/2088 56/18639 0.160714285714286 1.43465209359606 0.170029118565154 0.839086788366248 GO:0030170 pyridoxal phosphate binding 9/2088 56/18639 0.160714285714286 1.43465209359606 0.170029118565154 0.839086788366248 GO:0005172 vascular endothelial growth factor receptor binding 3/2088 13/18639 0.230769230769231 2.06001326259947 0.17159857931099 0.840002722917509 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 3/2088 13/18639 0.230769230769231 2.06001326259947 0.17159857931099 0.840002722917509 GO:0051020 GTPase binding 41/2088 315/18639 0.13015873015873 1.16189107827039 0.172993139090068 0.843428397009406 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 23/2088 167/18639 0.137724550898204 1.22942907288871 0.173707825479603 0.843525200528954 GO:0004674 protein serine/threonine kinase activity 55/2088 433/18639 0.1270207852194 1.13387950943697 0.176900490448105 0.855606356191231 GO:0016405 CoA-ligase activity 5/2088 27/18639 0.185185185185185 1.65309706257982 0.178443488804133 0.859644426223086 GO:0070279 vitamin B6 binding 9/2088 57/18639 0.157894736842105 1.40948275862069 0.183199208704333 0.873555249794204 GO:0019903 protein phosphatase binding 20/2088 144/18639 0.138888888888889 1.23982279693487 0.183709726809562 0.873555249794204 GO:0004402 histone acetyltransferase activity 7/2088 42/18639 0.166666666666667 1.48778735632184 0.184928912023979 0.873555249794204 GO:0008307 structural constituent of muscle 7/2088 42/18639 0.166666666666667 1.48778735632184 0.184928912023979 0.873555249794204 GO:0043175 RNA polymerase core enzyme binding 7/2088 42/18639 0.166666666666667 1.48778735632184 0.184928912023979 0.873555249794204 GO:0008017 microtubule binding 36/2088 276/18639 0.130434782608696 1.16435532233883 0.187592197097001 0.882701268510696 GO:0032813 tumor necrosis factor receptor superfamily binding 8/2088 50/18639 0.16 1.42827586206897 0.191960422289142 0.899768156984626 GO:0031625 ubiquitin protein ligase binding 39/2088 302/18639 0.129139072847682 1.15278887873944 0.193453818734813 0.903004687497923 GO:0003697 single-stranded DNA binding 17/2088 121/18639 0.140495867768595 1.25416785408948 0.194138569552684 0.903004687497923 GO:0036408 histone H3K14 acetyltransferase activity 5/2088 28/18639 0.178571428571429 1.5940578817734 0.198587352662452 0.918855581150386 GO:0004712 protein serine/threonine/tyrosine kinase activity 7/2088 43/18639 0.162790697674419 1.45318765036087 0.201056347822661 0.918855581150386 GO:0030983 mismatched DNA binding 3/2088 14/18639 0.214285714285714 1.91286945812808 0.201280315892092 0.918855581150386 GO:0031404 chloride ion binding 3/2088 14/18639 0.214285714285714 1.91286945812808 0.201280315892092 0.918855581150386 GO:0003684 damaged DNA binding 11/2088 74/18639 0.148648648648649 1.32694547996272 0.202328492184526 0.918855581150386 GO:0005123 death receptor binding 4/2088 21/18639 0.19047619047619 1.70032840722496 0.202844559924467 0.918855581150386 GO:0051010 microtubule plus-end binding 4/2088 21/18639 0.19047619047619 1.70032840722496 0.202844559924467 0.918855581150386 GO:0008168 methyltransferase activity 27/2088 204/18639 0.132352941176471 1.18147819472617 0.204959267523184 0.924983460123215 GO:0000993 RNA polymerase II complex binding 6/2088 36/18639 0.166666666666667 1.48778735632184 0.21033987023541 0.942260525704015 GO:0004033 aldo-keto reductase (NADPH) activity 6/2088 36/18639 0.166666666666667 1.48778735632184 0.21033987023541 0.942260525704015 GO:0031072 heat shock protein binding 18/2088 131/18639 0.137404580152672 1.22657278231113 0.21201904339335 0.946290877498262 GO:0019887 protein kinase regulator activity 33/2088 255/18639 0.129411764705882 1.15522312373225 0.212913529701341 0.946802289587649 GO:0019205 nucleobase-containing compound kinase activity 7/2088 44/18639 0.159090909090909 1.42016065830721 0.217701627387659 0.961813211263656 GO:0004181 metallocarboxypeptidase activity 5/2088 29/18639 0.172413793103448 1.5390903686088 0.219458203888001 0.961813211263656 GO:0010484 histone H3 acetyltransferase activity 5/2088 29/18639 0.172413793103448 1.5390903686088 0.219458203888001 0.961813211263656 GO:0043236 laminin binding 5/2088 29/18639 0.172413793103448 1.5390903686088 0.219458203888001 0.961813211263656 GO:0008649 rRNA methyltransferase activity 4/2088 22/18639 0.181818181818182 1.6230407523511 0.227529507091081 0.988376840203575 GO:0031267 small GTPase binding 36/2088 283/18639 0.127208480565371 1.13555501401243 0.231860783368075 0.988376840203575 GO:0000774 adenyl-nucleotide exchange factor activity 3/2088 15/18639 0.2 1.78534482758621 0.23203245424878 0.988376840203575 GO:0004089 carbonate dehydratase activity 3/2088 15/18639 0.2 1.78534482758621 0.23203245424878 0.988376840203575 GO:0042809 nuclear vitamin D receptor binding 3/2088 15/18639 0.2 1.78534482758621 0.23203245424878 0.988376840203575 GO:0140776 protein-containing complex destabilizing activity 3/2088 15/18639 0.2 1.78534482758621 0.23203245424878 0.988376840203575 GO:0141050 histone H3K deacetylase activity 3/2088 15/18639 0.2 1.78534482758621 0.23203245424878 0.988376840203575 GO:0141051 histone H4K deacetylase activity 3/2088 15/18639 0.2 1.78534482758621 0.23203245424878 0.988376840203575 GO:0051539 4 iron, 4 sulfur cluster binding 7/2088 45/18639 0.155555555555556 1.38860153256705 0.234818178889052 0.99674569640318 GO:0004864 protein phosphatase inhibitor activity 8/2088 53/18639 0.150943396226415 1.34743005855563 0.238175777047038 0.999999999999902 GO:0019905 syntaxin binding 9/2088 61/18639 0.147540983606557 1.31705765969474 0.239982007689966 0.999999999999902 GO:0016769 transferase activity, transferring nitrogenous groups 5/2088 30/18639 0.166666666666667 1.48778735632184 0.24095856753751 0.999999999999902 GO:0043995 histone H4K5 acetyltransferase activity 5/2088 30/18639 0.166666666666667 1.48778735632184 0.24095856753751 0.999999999999902 GO:0043996 histone H4K8 acetyltransferase activity 5/2088 30/18639 0.166666666666667 1.48778735632184 0.24095856753751 0.999999999999902 GO:0043997 histone H4K12 acetyltransferase activity 5/2088 30/18639 0.166666666666667 1.48778735632184 0.24095856753751 0.999999999999902 GO:0004518 nuclease activity 27/2088 209/18639 0.129186602870813 1.1532131661442 0.243244283552747 0.999999999999902 GO:0051015 actin filament binding 27/2088 209/18639 0.129186602870813 1.1532131661442 0.243244283552747 0.999999999999902 GO:0042162 telomeric DNA binding 6/2088 38/18639 0.157894736842105 1.40948275862069 0.248327798900307 0.999999999999902 GO:0004180 carboxypeptidase activity 7/2088 46/18639 0.152173913043478 1.35841454272864 0.252357683874688 0.999999999999902 GO:0141003 histone H2AX kinase activity 44/2088 354/18639 0.124293785310734 1.10953633352815 0.252678506918422 0.999999999999902 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 12/2088 86/18639 0.13953488372093 1.24558941459503 0.252859440249356 0.999999999999902 GO:0050660 flavin adenine dinucleotide binding 12/2088 86/18639 0.13953488372093 1.24558941459503 0.252859440249356 0.999999999999902 GO:0004602 glutathione peroxidase activity 4/2088 23/18639 0.173913043478261 1.55247376311844 0.252912524574037 0.999999999999902 GO:0043274 phospholipase binding 4/2088 23/18639 0.173913043478261 1.55247376311844 0.252912524574037 0.999999999999902 GO:0097110 scaffold protein binding 10/2088 70/18639 0.142857142857143 1.27524630541872 0.254886883754801 0.999999999999902 GO:0005164 tumor necrosis factor receptor binding 5/2088 31/18639 0.161290322580645 1.43979421579533 0.262989781321895 0.999999999999902 GO:0016878 acid-thiol ligase activity 5/2088 31/18639 0.161290322580645 1.43979421579533 0.262989781321895 0.999999999999902 GO:0005149 interleukin-1 receptor binding 3/2088 16/18639 0.1875 1.67376077586207 0.263543260174216 0.999999999999902 GO:0005324 long-chain fatty acid transmembrane transporter activity 3/2088 16/18639 0.1875 1.67376077586207 0.263543260174216 0.999999999999902 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/2088 16/18639 0.1875 1.67376077586207 0.263543260174216 0.999999999999902 GO:0034450 ubiquitin-ubiquitin ligase activity 3/2088 16/18639 0.1875 1.67376077586207 0.263543260174216 0.999999999999902 GO:0005200 structural constituent of cytoskeleton 15/2088 112/18639 0.133928571428571 1.19554341133005 0.270241424822543 0.999999999999902 GO:0005507 copper ion binding 9/2088 63/18639 0.142857142857143 1.27524630541872 0.270447582721456 0.999999999999902 GO:0140996 histone H3 kinase activity 44/2088 357/18639 0.123249299719888 1.10021249879262 0.271624725949999 0.999999999999902 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 43/2088 349/18639 0.123209169054441 1.09985426341271 0.275187634381289 0.999999999999902 GO:0000287 magnesium ion binding 29/2088 230/18639 0.126086956521739 1.12554347826087 0.276610186912663 0.999999999999902 GO:0005315 phosphate transmembrane transporter activity 4/2088 24/18639 0.166666666666667 1.48778735632184 0.278835217514651 0.999999999999902 GO:0070300 phosphatidic acid binding 4/2088 24/18639 0.166666666666667 1.48778735632184 0.278835217514651 0.999999999999902 GO:0050997 quaternary ammonium group binding 6/2088 40/18639 0.15 1.33900862068966 0.288056959664063 0.999999999999902 GO:0071949 FAD binding 6/2088 40/18639 0.15 1.33900862068966 0.288056959664063 0.999999999999902 GO:0035173 histone kinase activity 44/2088 360/18639 0.122222222222222 1.09104406130268 0.291135002757982 0.999999999999902 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/2088 17/18639 0.176470588235294 1.57530425963489 0.29552372723997 0.999999999999902 GO:0017110 nucleoside diphosphate phosphatase activity 3/2088 17/18639 0.176470588235294 1.57530425963489 0.29552372723997 0.999999999999902 GO:0031489 myosin V binding 3/2088 17/18639 0.176470588235294 1.57530425963489 0.29552372723997 0.999999999999902 GO:0048038 quinone binding 3/2088 17/18639 0.176470588235294 1.57530425963489 0.29552372723997 0.999999999999902 GO:0019902 phosphatase binding 24/2088 190/18639 0.126315789473684 1.12758620689655 0.296774921670347 0.999999999999902 GO:0004521 RNA endonuclease activity 10/2088 73/18639 0.136986301369863 1.22283892300425 0.298884171903554 0.999999999999902 GO:0035091 phosphatidylinositol binding 35/2088 284/18639 0.123239436619718 1.10012445361826 0.299229562700272 0.999999999999902 GO:0004601 peroxidase activity 8/2088 57/18639 0.140350877192982 1.25287356321839 0.304752602163048 0.999999999999902 GO:0015932 nucleobase-containing compound transmembrane transporter activity 8/2088 57/18639 0.140350877192982 1.25287356321839 0.304752602163048 0.999999999999902 GO:0005251 delayed rectifier potassium channel activity 4/2088 25/18639 0.16 1.42827586206897 0.305144448135197 0.999999999999902 GO:0042974 nuclear retinoic acid receptor binding 4/2088 25/18639 0.16 1.42827586206897 0.305144448135197 0.999999999999902 GO:0047617 fatty acyl-CoA hydrolase activity 4/2088 25/18639 0.16 1.42827586206897 0.305144448135197 0.999999999999902 GO:0016763 pentosyltransferase activity 7/2088 49/18639 0.142857142857143 1.27524630541872 0.307014585526407 0.999999999999902 GO:0016877 ligase activity, forming carbon-sulfur bonds 6/2088 41/18639 0.146341463414634 1.30634987384357 0.308404384872104 0.999999999999902 GO:0140318 protein transporter activity 6/2088 41/18639 0.146341463414634 1.30634987384357 0.308404384872104 0.999999999999902 GO:0019888 protein phosphatase regulator activity 14/2088 107/18639 0.130841121495327 1.1679825974863 0.310014126969964 0.999999999999902 GO:0000182 rDNA binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0001094 TFIID-class transcription factor complex binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0004090 carbonyl reductase (NADPH) activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0005345 purine nucleobase transmembrane transporter activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0005381 iron ion transmembrane transporter activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0005522 profilin binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0008140 cAMP response element binding protein binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0008239 dipeptidyl-peptidase activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0016427 tRNA (cytidine) methyltransferase activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0016868 intramolecular phosphotransferase activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0019531 oxalate transmembrane transporter activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0032356 oxidized DNA binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0043295 glutathione binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0050815 phosphoserine residue binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0051880 G-quadruplex DNA binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0070097 delta-catenin binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0099122 RNA polymerase II C-terminal domain binding 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0141109 transporter activator activity 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/2088 10/18639 0.2 1.78534482758621 0.310676701074969 0.999999999999902 GO:0048029 monosaccharide binding 10/2088 74/18639 0.135135135135135 1.20631407269338 0.313970996859652 0.999999999999902 GO:0004721 phosphoprotein phosphatase activity 22/2088 175/18639 0.125714285714286 1.12221674876847 0.315415234488605 0.999999999999902 GO:0019842 vitamin binding 19/2088 150/18639 0.126666666666667 1.1307183908046 0.320105082489735 0.999999999999902 GO:0015605 organophosphate ester transmembrane transporter activity 7/2088 50/18639 0.14 1.24974137931034 0.325744333030148 0.999999999999902 GO:0003746 translation elongation factor activity 3/2088 18/18639 0.166666666666667 1.48778735632184 0.327710161657069 0.999999999999902 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/2088 18/18639 0.166666666666667 1.48778735632184 0.327710161657069 0.999999999999902 GO:0016854 racemase and epimerase activity 3/2088 18/18639 0.166666666666667 1.48778735632184 0.327710161657069 0.999999999999902 GO:0017075 syntaxin-1 binding 3/2088 18/18639 0.166666666666667 1.48778735632184 0.327710161657069 0.999999999999902 GO:0044183 protein folding chaperone 10/2088 75/18639 0.133333333333333 1.19022988505747 0.329224264792104 0.999999999999902 GO:0019208 phosphatase regulator activity 15/2088 117/18639 0.128205128205128 1.14445181255526 0.32971431861798 0.999999999999902 GO:1990782 protein tyrosine kinase binding 15/2088 117/18639 0.128205128205128 1.14445181255526 0.32971431861798 0.999999999999902 GO:0051087 protein-folding chaperone binding 17/2088 134/18639 0.126865671641791 1.13249485331961 0.33061144942514 0.999999999999902 GO:0008376 acetylgalactosaminyltransferase activity 5/2088 34/18639 0.147058823529412 1.31275354969574 0.331290801880864 0.999999999999902 GO:0015035 protein-disulfide reductase activity 5/2088 34/18639 0.147058823529412 1.31275354969574 0.331290801880864 0.999999999999902 GO:0004112 cyclic-nucleotide phosphodiesterase activity 4/2088 26/18639 0.153846153846154 1.37334217506631 0.331694087101812 0.999999999999902 GO:0016289 acyl-CoA hydrolase activity 4/2088 26/18639 0.153846153846154 1.37334217506631 0.331694087101812 0.999999999999902 GO:0030247 polysaccharide binding 4/2088 26/18639 0.153846153846154 1.37334217506631 0.331694087101812 0.999999999999902 GO:0034237 protein kinase A regulatory subunit binding 4/2088 26/18639 0.153846153846154 1.37334217506631 0.331694087101812 0.999999999999902 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/2088 59/18639 0.135593220338983 1.2104032729398 0.339467509604631 0.999999999999902 GO:0045309 protein phosphorylated amino acid binding 8/2088 59/18639 0.135593220338983 1.2104032729398 0.339467509604631 0.999999999999902 GO:0015631 tubulin binding 46/2088 385/18639 0.119480519480519 1.06656963725929 0.343011981251038 0.999999999999902 GO:0033218 amide binding 30/2088 247/18639 0.121457489878543 1.0842175066313 0.346939901827294 0.999999999999902 GO:0002020 protease binding 17/2088 136/18639 0.125 1.11584051724138 0.353616470429719 0.999999999999902 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0005225 volume-sensitive anion channel activity 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0008271 secondary active sulfate transmembrane transporter activity 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0008432 JUN kinase binding 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0008503 benzodiazepine receptor activity 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0015205 nucleobase transmembrane transporter activity 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0019215 intermediate filament binding 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0047676 arachidonate-CoA ligase activity 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:1900750 oligopeptide binding 2/2088 11/18639 0.181818181818182 1.6230407523511 0.353765001491143 0.999999999999902 GO:0010485 histone H4 acetyltransferase activity 5/2088 35/18639 0.142857142857143 1.27524630541872 0.354478163486873 0.999999999999902 GO:0016229 steroid dehydrogenase activity 5/2088 35/18639 0.142857142857143 1.27524630541872 0.354478163486873 0.999999999999902 GO:0004364 glutathione transferase activity 4/2088 27/18639 0.148148148148148 1.32247765006386 0.358346365066626 0.999999999999902 GO:0004683 calcium/calmodulin-dependent protein kinase activity 4/2088 27/18639 0.148148148148148 1.32247765006386 0.358346365066626 0.999999999999902 GO:0008320 protein transmembrane transporter activity 4/2088 27/18639 0.148148148148148 1.32247765006386 0.358346365066626 0.999999999999902 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/2088 27/18639 0.148148148148148 1.32247765006386 0.358346365066626 0.999999999999902 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/2088 19/18639 0.157894736842105 1.40948275862069 0.35986548303945 0.999999999999902 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/2088 19/18639 0.157894736842105 1.40948275862069 0.35986548303945 0.999999999999902 GO:0015245 fatty acid transmembrane transporter activity 3/2088 19/18639 0.157894736842105 1.40948275862069 0.35986548303945 0.999999999999902 GO:0140036 ubiquitin-modified protein reader activity 3/2088 19/18639 0.157894736842105 1.40948275862069 0.35986548303945 0.999999999999902 GO:1990380 K48-linked deubiquitinase activity 3/2088 19/18639 0.157894736842105 1.40948275862069 0.35986548303945 0.999999999999902 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/2088 52/18639 0.134615384615385 1.20167440318302 0.363668539242655 0.999999999999902 GO:0030159 signaling receptor complex adaptor activity 7/2088 52/18639 0.134615384615385 1.20167440318302 0.363668539242655 0.999999999999902 GO:0140104 molecular carrier activity 30/2088 249/18639 0.120481927710843 1.07550893228085 0.364088956795308 0.999999999999902 GO:0004722 protein serine/threonine phosphatase activity 13/2088 103/18639 0.12621359223301 1.12667392032139 0.367868703073491 0.999999999999902 GO:0001223 transcription coactivator binding 6/2088 44/18639 0.136363636363636 1.21728056426332 0.370574958400347 0.999999999999902 GO:0045505 dynein intermediate chain binding 5/2088 36/18639 0.138888888888889 1.23982279693487 0.377726275301625 0.999999999999902 GO:0003779 actin binding 52/2088 443/18639 0.117381489841986 1.04783217871877 0.381006198969581 0.999999999999902 GO:0051018 protein kinase A binding 7/2088 53/18639 0.132075471698113 1.17900130123617 0.382765263924597 0.999999999999902 GO:0140296 general transcription initiation factor binding 7/2088 53/18639 0.132075471698113 1.17900130123617 0.382765263924597 0.999999999999902 GO:0016782 transferase activity, transferring sulphur-containing groups 9/2088 70/18639 0.128571428571429 1.14772167487685 0.383763060747613 0.999999999999902 GO:0033293 monocarboxylic acid binding 10/2088 79/18639 0.126582278481013 1.12996508075076 0.391369406953202 0.999999999999902 GO:0004715 non-membrane spanning protein tyrosine kinase activity 6/2088 45/18639 0.133333333333333 1.19022988505747 0.3914606167867 0.999999999999902 GO:0000339 RNA cap binding 3/2088 20/18639 0.15 1.33900862068966 0.391779543006897 0.999999999999902 GO:0016408 C-acyltransferase activity 3/2088 20/18639 0.15 1.33900862068966 0.391779543006897 0.999999999999902 GO:0004032 aldose reductase (NADPH) activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0005095 GTPase inhibitor activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0016273 arginine N-methyltransferase activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0016274 protein-arginine N-methyltransferase activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0016840 carbon-nitrogen lyase activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0043047 single-stranded telomeric DNA binding 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/2088 12/18639 0.166666666666667 1.48778735632184 0.395854508256913 0.999999999999902 GO:0140299 molecular sensor activity 9/2088 71/18639 0.126760563380282 1.1315565808645 0.400376349134522 0.999999999999902 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/2088 54/18639 0.12962962962963 1.15716794380587 0.401888724921777 0.999999999999902 GO:0050661 NADP binding 7/2088 54/18639 0.12962962962963 1.15716794380587 0.401888724921777 0.999999999999902 GO:0048306 calcium-dependent protein binding 10/2088 80/18639 0.125 1.11584051724138 0.407057298487927 0.999999999999902 GO:0003785 actin monomer binding 4/2088 29/18639 0.137931034482759 1.23127229488704 0.411455213253346 0.999999999999902 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/2088 29/18639 0.137931034482759 1.23127229488704 0.411455213253346 0.999999999999902 GO:0030291 protein serine/threonine kinase inhibitor activity 6/2088 46/18639 0.130434782608696 1.16435532233883 0.412326056723502 0.999999999999902 GO:0101005 deubiquitinase activity 14/2088 115/18639 0.121739130434783 1.08673163418291 0.413055169254634 0.999999999999902 GO:0033192 calmodulin-dependent protein phosphatase activity 10/2088 81/18639 0.123456790123457 1.10206470838655 0.422754607360281 0.999999999999902 GO:0140791 histone H2AXS140 phosphatase activity 10/2088 81/18639 0.123456790123457 1.10206470838655 0.422754607360281 0.999999999999902 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 10/2088 81/18639 0.123456790123457 1.10206470838655 0.422754607360281 0.999999999999902 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 10/2088 81/18639 0.123456790123457 1.10206470838655 0.422754607360281 0.999999999999902 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 10/2088 81/18639 0.123456790123457 1.10206470838655 0.422754607360281 0.999999999999902 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 10/2088 81/18639 0.123456790123457 1.10206470838655 0.422754607360281 0.999999999999902 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 10/2088 81/18639 0.123456790123457 1.10206470838655 0.422754607360281 0.999999999999902 GO:1990439 MAP kinase serine/threonine phosphatase activity 10/2088 81/18639 0.123456790123457 1.10206470838655 0.422754607360281 0.999999999999902 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/2088 21/18639 0.142857142857143 1.27524630541872 0.423268706853968 0.999999999999902 GO:0035613 RNA stem-loop binding 3/2088 21/18639 0.142857142857143 1.27524630541872 0.423268706853968 0.999999999999902 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/2088 21/18639 0.142857142857143 1.27524630541872 0.423268706853968 0.999999999999902 GO:0140312 cargo adaptor activity 3/2088 21/18639 0.142857142857143 1.27524630541872 0.423268706853968 0.999999999999902 GO:1904047 S-adenosyl-L-methionine binding 3/2088 21/18639 0.142857142857143 1.27524630541872 0.423268706853968 0.999999999999902 GO:0004536 DNA nuclease activity 8/2088 64/18639 0.125 1.11584051724138 0.427909493825176 0.999999999999902 GO:0003689 DNA clamp loader activity 19/2088 160/18639 0.11875 1.06004849137931 0.429985869300015 0.999999999999902 GO:0001784 phosphotyrosine residue binding 6/2088 47/18639 0.127659574468085 1.13958180484226 0.43311466563433 0.999999999999902 GO:0043539 protein serine/threonine kinase activator activity 9/2088 73/18639 0.123287671232877 1.10055503070383 0.433613364849642 0.999999999999902 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/2088 13/18639 0.153846153846154 1.37334217506631 0.436628313519808 0.999999999999902 GO:0008035 high-density lipoprotein particle binding 2/2088 13/18639 0.153846153846154 1.37334217506631 0.436628313519808 0.999999999999902 GO:0019855 calcium channel inhibitor activity 2/2088 13/18639 0.153846153846154 1.37334217506631 0.436628313519808 0.999999999999902 GO:0035325 Toll-like receptor binding 2/2088 13/18639 0.153846153846154 1.37334217506631 0.436628313519808 0.999999999999902 GO:0035673 oligopeptide transmembrane transporter activity 2/2088 13/18639 0.153846153846154 1.37334217506631 0.436628313519808 0.999999999999902 GO:0051011 microtubule minus-end binding 2/2088 13/18639 0.153846153846154 1.37334217506631 0.436628313519808 0.999999999999902 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/2088 13/18639 0.153846153846154 1.37334217506631 0.436628313519808 0.999999999999902 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/2088 13/18639 0.153846153846154 1.37334217506631 0.436628313519808 0.999999999999902 GO:0031210 phosphatidylcholine binding 4/2088 30/18639 0.133333333333333 1.19022988505747 0.437685466440398 0.999999999999902 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 10/2088 82/18639 0.121951219512195 1.08862489486964 0.438436690908802 0.999999999999902 GO:0033549 MAP kinase phosphatase activity 10/2088 82/18639 0.121951219512195 1.08862489486964 0.438436690908802 0.999999999999902 GO:0000217 DNA secondary structure binding 5/2088 39/18639 0.128205128205128 1.14445181255526 0.447027934826722 0.999999999999902 GO:0140597 protein carrier chaperone 22/2088 188/18639 0.117021276595745 1.04461665443874 0.44774138002134 0.999999999999902 GO:0140693 molecular condensate scaffold activity 6/2088 48/18639 0.125 1.11584051724138 0.453772983672473 0.999999999999902 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 10/2088 83/18639 0.120481927710843 1.07550893228085 0.454079611531214 0.999999999999902 GO:0008093 cytoskeletal anchor activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0032931 histone H3K56 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0043992 histone H3K9 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0043993 histone H3K18 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0043994 histone H3K23 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0043999 histone H2AK5 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0044012 histone H2AK9 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0044014 histone H2BK5 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0044015 histone H2BK12 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0044016 histone H3K4 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0044017 histone H3K27 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0044018 histone H3K36 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0140035 ubiquitin-like protein reader activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0140908 histone H3K122 acetyltransferase activity 3/2088 22/18639 0.136363636363636 1.21728056426332 0.454174896290214 0.999999999999902 GO:0019783 ubiquitin-like protein peptidase activity 15/2088 127/18639 0.118110236220472 1.05433749660603 0.454992835699217 0.999999999999902 GO:0052689 carboxylic ester hydrolase activity 11/2088 92/18639 0.119565217391304 1.06732571214393 0.457455210784547 0.999999999999902 GO:0008235 metalloexopeptidase activity 8/2088 66/18639 0.121212121212121 1.08202716823406 0.463174695664882 0.999999999999902 GO:0005310 dicarboxylic acid transmembrane transporter activity 4/2088 31/18639 0.129032258064516 1.15183537263626 0.463566308680176 0.999999999999902 GO:0005452 solute:inorganic anion antiporter activity 4/2088 31/18639 0.129032258064516 1.15183537263626 0.463566308680176 0.999999999999902 GO:0017018 myosin phosphatase activity 10/2088 84/18639 0.119047619047619 1.0627052545156 0.469660217657984 0.999999999999902 GO:0051117 ATPase binding 10/2088 84/18639 0.119047619047619 1.0627052545156 0.469660217657984 0.999999999999902 GO:0015036 disulfide oxidoreductase activity 5/2088 40/18639 0.125 1.11584051724138 0.469738074135674 0.999999999999902 GO:0030331 nuclear estrogen receptor binding 5/2088 40/18639 0.125 1.11584051724138 0.469738074135674 0.999999999999902 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 5/2088 40/18639 0.125 1.11584051724138 0.469738074135674 0.999999999999902 GO:0061791 GTPase motor activity 5/2088 40/18639 0.125 1.11584051724138 0.469738074135674 0.999999999999902 GO:0071855 neuropeptide receptor binding 5/2088 40/18639 0.125 1.11584051724138 0.469738074135674 0.999999999999902 GO:0140662 ATP-dependent protein folding chaperone 5/2088 40/18639 0.125 1.11584051724138 0.469738074135674 0.999999999999902 GO:1990606 membrane scission GTPase motor activity 5/2088 40/18639 0.125 1.11584051724138 0.469738074135674 0.999999999999902 GO:0051213 dioxygenase activity 11/2088 93/18639 0.118279569892473 1.05584909158324 0.472259760403788 0.999999999999902 GO:0060590 ATPase regulator activity 6/2088 49/18639 0.122448979591837 1.09306826178747 0.474250899692853 0.999999999999902 GO:0005161 platelet-derived growth factor receptor binding 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0008195 phosphatidate phosphatase activity 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0008559 ABC-type xenobiotic transporter activity 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0032036 myosin heavy chain binding 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0043176 amine binding 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0070742 C2H2 zinc finger domain binding 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0098847 sequence-specific single stranded DNA binding 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:1901612 cardiolipin binding 2/2088 14/18639 0.142857142857143 1.27524630541872 0.475852979791095 0.999999999999902 GO:0044013 histone H2B acetyltransferase activity 3/2088 23/18639 0.130434782608696 1.16435532233883 0.48436425204764 0.999999999999902 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/2088 23/18639 0.130434782608696 1.16435532233883 0.48436425204764 0.999999999999902 GO:0015106 bicarbonate transmembrane transporter activity 4/2088 32/18639 0.125 1.11584051724138 0.489011021692001 0.999999999999902 GO:0022884 macromolecule transmembrane transporter activity 4/2088 32/18639 0.125 1.11584051724138 0.489011021692001 0.999999999999902 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/2088 32/18639 0.125 1.11584051724138 0.489011021692001 0.999999999999902 GO:0043425 bHLH transcription factor binding 4/2088 32/18639 0.125 1.11584051724138 0.489011021692001 0.999999999999902 GO:0004812 aminoacyl-tRNA ligase activity 5/2088 41/18639 0.121951219512195 1.08862489486964 0.492145530977836 0.999999999999902 GO:0016875 ligase activity, forming carbon-oxygen bonds 5/2088 41/18639 0.121951219512195 1.08862489486964 0.492145530977836 0.999999999999902 GO:0042169 SH2 domain binding 5/2088 41/18639 0.121951219512195 1.08862489486964 0.492145530977836 0.999999999999902 GO:0140828 metal cation:monoatomic cation antiporter activity 5/2088 41/18639 0.121951219512195 1.08862489486964 0.492145530977836 0.999999999999902 GO:0030145 manganese ion binding 8/2088 68/18639 0.117647058823529 1.05020283975659 0.497974800556028 0.999999999999902 GO:0016209 antioxidant activity 10/2088 86/18639 0.116279069767442 1.03799117882919 0.500546233450811 0.999999999999902 GO:0140097 catalytic activity, acting on DNA 38/2088 336/18639 0.113095238095238 1.00956999178982 0.501020597525123 0.999999999999902 GO:0005543 phospholipid binding 56/2088 497/18639 0.112676056338028 1.00582807187955 0.503035798756875 0.999999999999902 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0010181 FMN binding 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0015116 sulfate transmembrane transporter activity 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0047372 monoacylglycerol lipase activity 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0048531 beta-1,3-galactosyltransferase activity 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0050700 CARD domain binding 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0051371 muscle alpha-actinin binding 2/2088 15/18639 0.133333333333333 1.19022988505747 0.513363829874528 0.999999999999902 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0004622 lysophospholipase activity 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0015149 hexose transmembrane transporter activity 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0015295 solute:proton symporter activity 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0043998 histone H2A acetyltransferase activity 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0050699 WW domain binding 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0055056 D-glucose transmembrane transporter activity 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0060229 lipase activator activity 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0140612 DNA damage sensor activity 3/2088 24/18639 0.125 1.11584051724138 0.513725542695211 0.999999999999902 GO:0019239 deaminase activity 4/2088 33/18639 0.121212121212121 1.08202716823406 0.513943306684894 0.999999999999902 GO:0071889 14-3-3 protein binding 4/2088 33/18639 0.121212121212121 1.08202716823406 0.513943306684894 0.999999999999902 GO:0016859 cis-trans isomerase activity 5/2088 42/18639 0.119047619047619 1.0627052545156 0.514194436468518 0.999999999999902 GO:0042056 chemoattractant activity 5/2088 42/18639 0.119047619047619 1.0627052545156 0.514194436468518 0.999999999999902 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 7/2088 60/18639 0.116666666666667 1.04145114942529 0.514796533709892 0.999999999999902 GO:0002039 p53 binding 8/2088 69/18639 0.115942028985507 1.03498250874563 0.5151264771453 0.999999999999902 GO:0000510 H3-H4 histone complex chaperone activity 17/2088 151/18639 0.112582781456954 1.0049954327472 0.529744134985372 0.999999999999902 GO:0140584 chromatin extrusion motor activity 17/2088 151/18639 0.112582781456954 1.0049954327472 0.529744134985372 0.999999999999902 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 17/2088 151/18639 0.112582781456954 1.0049954327472 0.529744134985372 0.999999999999902 GO:0140849 ATP-dependent H2AZ histone chaperone activity 17/2088 151/18639 0.112582781456954 1.0049954327472 0.529744134985372 0.999999999999902 GO:0031406 carboxylic acid binding 21/2088 187/18639 0.112299465240642 1.00246634704038 0.529868222271153 0.999999999999902 GO:0001221 transcription coregulator binding 13/2088 115/18639 0.11304347826087 1.00910794602699 0.530074064339571 0.999999999999902 GO:0046332 SMAD binding 9/2088 79/18639 0.113924050632911 1.01696857267569 0.531421002376234 0.999999999999902 GO:0052866 phosphatidylinositol phosphate phosphatase activity 4/2088 34/18639 0.117647058823529 1.05020283975659 0.538296973992098 0.999999999999902 GO:0001217 DNA-binding transcription repressor activity 31/2088 278/18639 0.111510791366906 0.995426072934756 0.539511152860732 0.999999999999902 GO:0015616 DNA translocase activity 17/2088 152/18639 0.111842105263158 0.998383620689655 0.541216465756747 0.999999999999902 GO:0140674 ATP-dependent histone chaperone activity 17/2088 152/18639 0.111842105263158 0.998383620689655 0.541216465756747 0.999999999999902 GO:0008483 transaminase activity 3/2088 25/18639 0.12 1.07120689655172 0.542168419226122 0.999999999999902 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/2088 25/18639 0.12 1.07120689655172 0.542168419226122 0.999999999999902 GO:0120020 cholesterol transfer activity 3/2088 25/18639 0.12 1.07120689655172 0.542168419226122 0.999999999999902 GO:0004725 protein tyrosine phosphatase activity 11/2088 98/18639 0.112244897959184 1.00197923997185 0.544813468389445 0.999999999999902 GO:0008170 N-methyltransferase activity 11/2088 98/18639 0.112244897959184 1.00197923997185 0.544813468389445 0.999999999999902 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 10/2088 89/18639 0.112359550561798 1.00300271212708 0.54588157767294 0.999999999999902 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 10/2088 89/18639 0.112359550561798 1.00300271212708 0.54588157767294 0.999999999999902 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0004707 MAP kinase activity 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0004708 MAP kinase kinase activity 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0005159 insulin-like growth factor receptor binding 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0005521 lamin binding 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0008142 oxysterol binding 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0015378 sodium:chloride symporter activity 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0015385 sodium:proton antiporter activity 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0016722 oxidoreductase activity, acting on metal ions 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0019841 retinol binding 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0097027 ubiquitin-protein transferase activator activity 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/2088 16/18639 0.125 1.11584051724138 0.549052482688858 0.999999999999902 GO:0043177 organic acid binding 21/2088 189/18639 0.111111111111111 0.991858237547893 0.550457656919965 0.999999999999902 GO:0061775 cohesin loader activity 17/2088 153/18639 0.111111111111111 0.991858237547893 0.552602100358216 0.999999999999902 GO:0140793 histone H2AXY142 phosphatase activity 10/2088 90/18639 0.111111111111111 0.991858237547893 0.560654094484741 0.999999999999902 GO:0061631 ubiquitin conjugating enzyme activity 4/2088 35/18639 0.114285714285714 1.02019704433498 0.562015530186321 0.999999999999902 GO:0019838 growth factor binding 15/2088 136/18639 0.110294117647059 0.984565162271805 0.566144584987373 0.999999999999902 GO:1901682 sulfur compound transmembrane transporter activity 7/2088 63/18639 0.111111111111111 0.991858237547893 0.568421613042159 0.999999999999902 GO:0005112 Notch binding 3/2088 26/18639 0.115384615384615 1.03000663129973 0.569621592981466 0.999999999999902 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/2088 26/18639 0.115384615384615 1.03000663129973 0.569621592981466 0.999999999999902 GO:0015145 monosaccharide transmembrane transporter activity 3/2088 26/18639 0.115384615384615 1.03000663129973 0.569621592981466 0.999999999999902 GO:0030507 spectrin binding 3/2088 26/18639 0.115384615384615 1.03000663129973 0.569621592981466 0.999999999999902 GO:0043548 phosphatidylinositol 3-kinase binding 3/2088 26/18639 0.115384615384615 1.03000663129973 0.569621592981466 0.999999999999902 GO:0070412 R-SMAD binding 3/2088 26/18639 0.115384615384615 1.03000663129973 0.569621592981466 0.999999999999902 GO:0097602 cullin family protein binding 3/2088 26/18639 0.115384615384615 1.03000663129973 0.569621592981466 0.999999999999902 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 6/2088 54/18639 0.111111111111111 0.991858237547893 0.572429214996054 0.999999999999902 GO:0016791 phosphatase activity 30/2088 273/18639 0.10989010989011 0.980958696475938 0.573675216520154 0.999999999999902 GO:0140713 histone chaperone activity 18/2088 164/18639 0.109756097560976 0.979762405382675 0.573834716853202 0.999999999999902 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 14/2088 128/18639 0.109375 0.976360452586207 0.579762051265767 0.999999999999902 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/2088 17/18639 0.117647058823529 1.05020283975659 0.58285631674871 0.999999999999902 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/2088 17/18639 0.117647058823529 1.05020283975659 0.58285631674871 0.999999999999902 GO:0016805 dipeptidase activity 2/2088 17/18639 0.117647058823529 1.05020283975659 0.58285631674871 0.999999999999902 GO:0032977 membrane insertase activity 2/2088 17/18639 0.117647058823529 1.05020283975659 0.58285631674871 0.999999999999902 GO:0036041 long-chain fatty acid binding 2/2088 17/18639 0.117647058823529 1.05020283975659 0.58285631674871 0.999999999999902 GO:0038191 neuropilin binding 2/2088 17/18639 0.117647058823529 1.05020283975659 0.58285631674871 0.999999999999902 GO:0070402 NADPH binding 2/2088 17/18639 0.117647058823529 1.05020283975659 0.58285631674871 0.999999999999902 GO:1990226 histone methyltransferase binding 2/2088 17/18639 0.117647058823529 1.05020283975659 0.58285631674871 0.999999999999902 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/2088 36/18639 0.111111111111111 0.991858237547893 0.585051687046907 0.999999999999902 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/2088 36/18639 0.111111111111111 0.991858237547893 0.585051687046907 0.999999999999902 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/2088 36/18639 0.111111111111111 0.991858237547893 0.585051687046907 0.999999999999902 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/2088 36/18639 0.111111111111111 0.991858237547893 0.585051687046907 0.999999999999902 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/2088 36/18639 0.111111111111111 0.991858237547893 0.585051687046907 0.999999999999902 GO:1901681 sulfur compound binding 30/2088 275/18639 0.109090909090909 0.973824451410658 0.590440926864767 0.999999999999902 GO:0008374 O-acyltransferase activity 6/2088 55/18639 0.109090909090909 0.973824451410658 0.590972343639599 0.999999999999902 GO:0005085 guanyl-nucleotide exchange factor activity 25/2088 230/18639 0.108695652173913 0.970296101949025 0.595273512428187 0.999999999999902 GO:0001671 ATPase activator activity 3/2088 27/18639 0.111111111111111 0.991858237547893 0.596030996470821 0.999999999999902 GO:0008266 poly(U) RNA binding 3/2088 27/18639 0.111111111111111 0.991858237547893 0.596030996470821 0.999999999999902 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/2088 27/18639 0.111111111111111 0.991858237547893 0.596030996470821 0.999999999999902 GO:0019209 kinase activator activity 16/2088 148/18639 0.108108108108108 0.965051258154706 0.599133503291536 0.999999999999902 GO:0120013 lipid transfer activity 7/2088 65/18639 0.107692307692308 0.961339522546419 0.60258524896403 0.999999999999902 GO:0051219 phosphoprotein binding 10/2088 93/18639 0.10752688172043 0.959862810530219 0.603728270870136 0.999999999999902 GO:0004540 RNA nuclease activity 13/2088 121/18639 0.107438016528926 0.959069535480194 0.606660385799429 0.999999999999902 GO:0030280 structural constituent of skin epidermis 4/2088 37/18639 0.108108108108108 0.965051258154706 0.60736681364995 0.999999999999902 GO:0070001 aspartic-type peptidase activity 4/2088 37/18639 0.108108108108108 0.965051258154706 0.60736681364995 0.999999999999902 GO:0140658 ATP-dependent chromatin remodeler activity 17/2088 158/18639 0.107594936708861 0.960470318638149 0.607958001291929 0.999999999999902 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 29/2088 268/18639 0.108208955223881 0.965951492537313 0.608061096611389 0.999999999999902 GO:0000400 four-way junction DNA binding 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:0000900 mRNA regulatory element binding translation repressor activity 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:0008308 voltage-gated monoatomic anion channel activity 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:0015373 monoatomic anion:sodium symporter activity 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:0017128 phospholipid scramblase activity 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:0031690 adrenergic receptor binding 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:0035615 clathrin adaptor activity 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:1901611 phosphatidylglycerol binding 2/2088 18/18639 0.111111111111111 0.991858237547893 0.614749586135165 0.999999999999902 GO:0043495 protein-membrane adaptor activity 5/2088 47/18639 0.106382978723404 0.949651504035216 0.617502303159601 0.999999999999902 GO:0051019 mitogen-activated protein kinase binding 3/2088 28/18639 0.107142857142857 0.956434729064039 0.621357971991241 0.999999999999902 GO:0051119 sugar transmembrane transporter activity 3/2088 28/18639 0.107142857142857 0.956434729064039 0.621357971991241 0.999999999999902 GO:0097718 disordered domain specific binding 3/2088 28/18639 0.107142857142857 0.956434729064039 0.621357971991241 0.999999999999902 GO:0030414 peptidase inhibitor activity 18/2088 169/18639 0.106508875739645 0.950775351968986 0.626617138804276 0.999999999999902 GO:0016504 peptidase activator activity 6/2088 57/18639 0.105263157894737 0.939655172413793 0.626744405254398 0.999999999999902 GO:0017022 myosin binding 8/2088 76/18639 0.105263157894737 0.939655172413793 0.62828986591274 0.999999999999902 GO:0061630 ubiquitin protein ligase activity 38/2088 353/18639 0.107648725212465 0.960950473771613 0.629068042744664 0.999999999999902 GO:0004867 serine-type endopeptidase inhibitor activity 10/2088 95/18639 0.105263157894737 0.939655172413793 0.631272417467246 0.999999999999902 GO:0050840 extracellular matrix binding 7/2088 67/18639 0.104477611940299 0.932642820380854 0.635281178586262 0.999999999999902 GO:0004866 endopeptidase inhibitor activity 17/2088 161/18639 0.105590062111801 0.942573356179053 0.639665427536486 0.999999999999902 GO:0061134 peptidase regulator activity 24/2088 226/18639 0.106194690265487 0.94797070491303 0.641456990030824 0.999999999999902 GO:0008301 DNA binding, bending 2/2088 19/18639 0.105263157894737 0.939655172413793 0.64473595120525 0.999999999999902 GO:0008381 mechanosensitive monoatomic ion channel activity 2/2088 19/18639 0.105263157894737 0.939655172413793 0.64473595120525 0.999999999999902 GO:0008574 plus-end-directed microtubule motor activity 2/2088 19/18639 0.105263157894737 0.939655172413793 0.64473595120525 0.999999999999902 GO:0016918 retinal binding 2/2088 19/18639 0.105263157894737 0.939655172413793 0.64473595120525 0.999999999999902 GO:0031420 alkali metal ion binding 2/2088 19/18639 0.105263157894737 0.939655172413793 0.64473595120525 0.999999999999902 GO:0042577 lipid phosphatase activity 2/2088 19/18639 0.105263157894737 0.939655172413793 0.64473595120525 0.999999999999902 GO:0046624 sphingolipid transporter activity 2/2088 19/18639 0.105263157894737 0.939655172413793 0.64473595120525 0.999999999999902 GO:0070003 threonine-type peptidase activity 2/2088 19/18639 0.105263157894737 0.939655172413793 0.64473595120525 0.999999999999902 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/2088 29/18639 0.103448275862069 0.923454221165279 0.645577521076383 0.999999999999902 GO:0016417 S-acyltransferase activity 3/2088 29/18639 0.103448275862069 0.923454221165279 0.645577521076383 0.999999999999902 GO:0035250 UDP-galactosyltransferase activity 3/2088 29/18639 0.103448275862069 0.923454221165279 0.645577521076383 0.999999999999902 GO:0097472 cyclin-dependent protein kinase activity 3/2088 29/18639 0.103448275862069 0.923454221165279 0.645577521076383 0.999999999999902 GO:0035401 histone H3Y41 kinase activity 12/2088 115/18639 0.104347826086957 0.931484257871064 0.647097884738573 0.999999999999902 GO:0140801 histone H2AXY142 kinase activity 12/2088 115/18639 0.104347826086957 0.931484257871064 0.647097884738573 0.999999999999902 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/2088 39/18639 0.102564102564103 0.915561450044209 0.649719197373025 0.999999999999902 GO:0005548 phospholipid transporter activity 7/2088 68/18639 0.102941176470588 0.918927484787018 0.65103764819629 0.999999999999902 GO:0001222 transcription corepressor binding 5/2088 49/18639 0.102040816326531 0.910890218156228 0.654982607081216 0.999999999999902 GO:0015459 potassium channel regulator activity 6/2088 59/18639 0.101694915254237 0.907802454704851 0.660636107102725 0.999999999999902 GO:0015297 antiporter activity 14/2088 135/18639 0.103703703703704 0.9257343550447 0.661171678771657 0.999999999999902 GO:0008094 ATP-dependent activity, acting on DNA 22/2088 210/18639 0.104761904761905 0.935180623973727 0.663759976440052 0.999999999999902 GO:0008187 poly-pyrimidine tract binding 3/2088 30/18639 0.1 0.892672413793103 0.668676638258159 0.999999999999902 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/2088 30/18639 0.1 0.892672413793103 0.668676638258159 0.999999999999902 GO:0070566 adenylyltransferase activity 3/2088 30/18639 0.1 0.892672413793103 0.668676638258159 0.999999999999902 GO:0004177 aminopeptidase activity 4/2088 40/18639 0.1 0.892672413793103 0.669717099954953 0.999999999999902 GO:0032451 demethylase activity 4/2088 40/18639 0.1 0.892672413793103 0.669717099954953 0.999999999999902 GO:0016779 nucleotidyltransferase activity 14/2088 136/18639 0.102941176470588 0.918927484787018 0.672076427238706 0.999999999999902 GO:0140789 histone phosphatase activity 14/2088 136/18639 0.102941176470588 0.918927484787018 0.672076427238706 0.999999999999902 GO:0015464 acetylcholine receptor activity 2/2088 20/18639 0.1 0.892672413793103 0.672842218782844 0.999999999999902 GO:0016004 phospholipase activator activity 2/2088 20/18639 0.1 0.892672413793103 0.672842218782844 0.999999999999902 GO:0016505 peptidase activator activity involved in apoptotic process 2/2088 20/18639 0.1 0.892672413793103 0.672842218782844 0.999999999999902 GO:0031418 L-ascorbic acid binding 2/2088 20/18639 0.1 0.892672413793103 0.672842218782844 0.999999999999902 GO:0052745 inositol phosphate phosphatase activity 2/2088 20/18639 0.1 0.892672413793103 0.672842218782844 0.999999999999902 GO:0061608 nuclear import signal receptor activity 2/2088 20/18639 0.1 0.892672413793103 0.672842218782844 0.999999999999902 GO:0140664 ATP-dependent DNA damage sensor activity 2/2088 20/18639 0.1 0.892672413793103 0.672842218782844 0.999999999999902 GO:0004386 helicase activity 16/2088 155/18639 0.103225806451613 0.92146829810901 0.673908688352651 0.999999999999902 GO:0004843 cysteine-type deubiquitinase activity 11/2088 108/18639 0.101851851851852 0.909203384418902 0.676607756036401 0.999999999999902 GO:0003727 single-stranded RNA binding 9/2088 89/18639 0.101123595505618 0.902702440914374 0.677690229360723 0.999999999999902 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/2088 41/18639 0.0975609756097561 0.870899915895711 0.688914026330858 0.999999999999902 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/2088 41/18639 0.0975609756097561 0.870899915895711 0.688914026330858 0.999999999999902 GO:0016597 amino acid binding 5/2088 51/18639 0.0980392156862745 0.875169033130494 0.690023718024656 0.999999999999902 GO:0030544 Hsp70 protein binding 5/2088 51/18639 0.0980392156862745 0.875169033130494 0.690023718024656 0.999999999999902 GO:0140457 protein demethylase activity 3/2088 31/18639 0.0967741935483871 0.863876529477197 0.690652744998657 0.999999999999902 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0004382 GDP phosphatase activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0004955 prostaglandin receptor activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0005031 tumor necrosis factor receptor activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0005337 nucleoside transmembrane transporter activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0008401 retinoic acid 4-hydroxylase activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0015187 glycine transmembrane transporter activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0015279 store-operated calcium channel activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0015643 toxic substance binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0030957 Tat protein binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0031419 cobalamin binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0035256 G protein-coupled glutamate receptor binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0042166 acetylcholine binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0042975 peroxisome proliferator activated receptor binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0043121 neurotrophin binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0043422 protein kinase B binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0050308 sugar-phosphatase activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0051864 histone H3K36 demethylase activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0071723 lipopeptide binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0098505 G-rich strand telomeric DNA binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0140135 mechanosensitive monoatomic cation channel activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0140940 histone H2A methyltransferase activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:1905394 retromer complex binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:1990259 histone H2AQ104 methyltransferase activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:1990757 ubiquitin ligase activator activity 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:1990763 arrestin family protein binding 1/2088 10/18639 0.1 0.892672413793103 0.695291913558392 0.999999999999902 GO:0061659 ubiquitin-like protein ligase activity 39/2088 372/18639 0.104838709677419 0.935866240266963 0.695568484351543 0.999999999999902 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/2088 21/18639 0.0952380952380952 0.850164203612479 0.699113114775357 0.999999999999902 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/2088 21/18639 0.0952380952380952 0.850164203612479 0.699113114775357 0.999999999999902 GO:0009975 cyclase activity 2/2088 21/18639 0.0952380952380952 0.850164203612479 0.699113114775357 0.999999999999902 GO:0019200 carbohydrate kinase activity 2/2088 21/18639 0.0952380952380952 0.850164203612479 0.699113114775357 0.999999999999902 GO:0051428 peptide hormone receptor binding 2/2088 21/18639 0.0952380952380952 0.850164203612479 0.699113114775357 0.999999999999902 GO:0030295 protein kinase activator activity 14/2088 139/18639 0.100719424460432 0.899094517489457 0.703579225490049 0.999999999999902 GO:0070851 growth factor receptor binding 14/2088 139/18639 0.100719424460432 0.899094517489457 0.703579225490049 0.999999999999902 GO:0019894 kinesin binding 4/2088 42/18639 0.0952380952380952 0.850164203612479 0.707305562105841 0.999999999999902 GO:0048487 beta-tubulin binding 4/2088 42/18639 0.0952380952380952 0.850164203612479 0.707305562105841 0.999999999999902 GO:0016247 channel regulator activity 17/2088 168/18639 0.101190476190476 0.90329946633826 0.708303397339029 0.999999999999902 GO:0008378 galactosyltransferase activity 3/2088 32/18639 0.09375 0.836880387931034 0.711512233616587 0.999999999999902 GO:0070717 poly-purine tract binding 3/2088 32/18639 0.09375 0.836880387931034 0.711512233616587 0.999999999999902 GO:0071813 lipoprotein particle binding 3/2088 32/18639 0.09375 0.836880387931034 0.711512233616587 0.999999999999902 GO:0071814 protein-lipid complex binding 3/2088 32/18639 0.09375 0.836880387931034 0.711512233616587 0.999999999999902 GO:0120015 sterol transfer activity 3/2088 32/18639 0.09375 0.836880387931034 0.711512233616587 0.999999999999902 GO:0004842 ubiquitin-protein transferase activity 47/2088 449/18639 0.10467706013363 0.934423239382536 0.713176899987135 0.999999999999902 GO:0004713 protein tyrosine kinase activity 14/2088 140/18639 0.1 0.892672413793103 0.713662922838769 0.999999999999902 GO:0005516 calmodulin binding 21/2088 207/18639 0.101449275362319 0.905609695152424 0.718159512452527 0.999999999999902 GO:0008238 exopeptidase activity 10/2088 102/18639 0.0980392156862745 0.875169033130494 0.719036850696399 0.999999999999902 GO:0015377 chloride:monoatomic cation symporter activity 2/2088 22/18639 0.0909090909090909 0.811520376175549 0.723606936623872 0.999999999999902 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/2088 22/18639 0.0909090909090909 0.811520376175549 0.723606936623872 0.999999999999902 GO:0046972 histone H4K16 acetyltransferase activity 2/2088 22/18639 0.0909090909090909 0.811520376175549 0.723606936623872 0.999999999999902 GO:0070034 telomerase RNA binding 2/2088 22/18639 0.0909090909090909 0.811520376175549 0.723606936623872 0.999999999999902 GO:0140784 metal ion sensor activity 2/2088 22/18639 0.0909090909090909 0.811520376175549 0.723606936623872 0.999999999999902 GO:0008375 acetylglucosaminyltransferase activity 4/2088 43/18639 0.0930232558139535 0.830392943063352 0.724892319372448 0.999999999999902 GO:0001540 amyloid-beta binding 8/2088 83/18639 0.0963855421686747 0.860407145824678 0.725337006660006 0.999999999999902 GO:0141108 transporter regulator activity 17/2088 170/18639 0.1 0.892672413793103 0.726399196914173 0.999999999999902 GO:0000099 sulfur amino acid transmembrane transporter activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0004016 adenylate cyclase activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0004954 prostanoid receptor activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0005536 D-glucose binding 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0008046 axon guidance receptor activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0008199 ferric iron binding 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0008526 phosphatidylinositol transfer activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0010854 adenylate cyclase regulator activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0019203 carbohydrate phosphatase activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0031731 CCR6 chemokine receptor binding 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0042608 T cell receptor binding 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0048407 platelet-derived growth factor binding 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0050786 RAGE receptor binding 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0050998 nitric-oxide synthase binding 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0097493 structural molecule activity conferring elasticity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0140031 phosphorylation-dependent protein binding 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0140537 transcription regulator activator activity 1/2088 11/18639 0.0909090909090909 0.811520376175549 0.729444604765117 0.999999999999902 GO:0030296 protein tyrosine kinase activator activity 3/2088 33/18639 0.0909090909090909 0.811520376175549 0.731269126309756 0.999999999999902 GO:0015485 cholesterol binding 5/2088 54/18639 0.0925925925925926 0.826548531289911 0.737875228361536 0.999999999999902 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/2088 23/18639 0.0869565217391304 0.77623688155922 0.74639195420256 0.999999999999902 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/2088 23/18639 0.0869565217391304 0.77623688155922 0.74639195420256 0.999999999999902 GO:0005212 structural constituent of eye lens 2/2088 23/18639 0.0869565217391304 0.77623688155922 0.74639195420256 0.999999999999902 GO:0005283 amino acid:sodium symporter activity 2/2088 23/18639 0.0869565217391304 0.77623688155922 0.74639195420256 0.999999999999902 GO:0016849 phosphorus-oxygen lyase activity 2/2088 23/18639 0.0869565217391304 0.77623688155922 0.74639195420256 0.999999999999902 GO:0042171 lysophosphatidic acid acyltransferase activity 2/2088 23/18639 0.0869565217391304 0.77623688155922 0.74639195420256 0.999999999999902 GO:0071617 lysophospholipid acyltransferase activity 2/2088 23/18639 0.0869565217391304 0.77623688155922 0.74639195420256 0.999999999999902 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/2088 23/18639 0.0869565217391304 0.77623688155922 0.74639195420256 0.999999999999902 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/2088 34/18639 0.0882352941176471 0.787652129817444 0.749943850727594 0.999999999999902 GO:0030332 cyclin binding 3/2088 34/18639 0.0882352941176471 0.787652129817444 0.749943850727594 0.999999999999902 GO:0046915 transition metal ion transmembrane transporter activity 4/2088 45/18639 0.0888888888888889 0.793486590038314 0.757675700385443 0.999999999999902 GO:0000340 RNA 7-methylguanosine cap binding 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0003995 acyl-CoA dehydrogenase activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0004000 adenosine deaminase activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0004126 cytidine deaminase activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0008603 cAMP-dependent protein kinase regulator activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0010853 cyclase activator activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0015166 polyol transmembrane transporter activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0015368 calcium:monoatomic cation antiporter activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0016801 hydrolase activity, acting on ether bonds 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0016803 ether hydrolase activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0031543 peptidyl-proline dioxygenase activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0035259 nuclear glucocorticoid receptor binding 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0036009 protein-glutamine N-methyltransferase activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0042301 phosphate ion binding 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0045295 gamma-catenin binding 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0070008 serine-type exopeptidase activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0070410 co-SMAD binding 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0140900 chloride:bicarbonate antiporter activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:1990459 transferrin receptor binding 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:1990817 poly(A) RNA polymerase activity 1/2088 12/18639 0.0833333333333333 0.74389367816092 0.759770977174953 0.999999999999902 GO:0008237 metallopeptidase activity 18/2088 184/18639 0.0978260869565217 0.873266491754123 0.763335674661424 0.999999999999902 GO:0061135 endopeptidase regulator activity 18/2088 184/18639 0.0978260869565217 0.873266491754123 0.763335674661424 0.999999999999902 GO:0170055 lipid transmembrane transporter activity 5/2088 56/18639 0.0892857142857143 0.7970289408867 0.766632271235979 0.999999999999902 GO:0004806 triacylglycerol lipase activity 2/2088 24/18639 0.0833333333333333 0.74389367816092 0.767543446157774 0.999999999999902 GO:0070840 dynein complex binding 2/2088 24/18639 0.0833333333333333 0.74389367816092 0.767543446157774 0.999999999999902 GO:0000175 3'-5'-RNA exonuclease activity 3/2088 35/18639 0.0857142857142857 0.765147783251231 0.767562130778339 0.999999999999902 GO:0005154 epidermal growth factor receptor binding 3/2088 35/18639 0.0857142857142857 0.765147783251231 0.767562130778339 0.999999999999902 GO:0043015 gamma-tubulin binding 3/2088 35/18639 0.0857142857142857 0.765147783251231 0.767562130778339 0.999999999999902 GO:0003714 transcription corepressor activity 20/2088 204/18639 0.0980392156862745 0.875169033130494 0.769098296636403 0.999999999999902 GO:0030276 clathrin binding 4/2088 46/18639 0.0869565217391304 0.77623688155922 0.772893710227876 0.999999999999902 GO:0019787 ubiquitin-like protein transferase activity 49/2088 479/18639 0.102296450939457 0.913172197825931 0.773224893884604 0.999999999999902 GO:0042054 histone methyltransferase activity 6/2088 67/18639 0.0895522388059701 0.799408131755018 0.775833125559087 0.999999999999902 GO:0042626 ATPase-coupled transmembrane transporter activity 9/2088 98/18639 0.0918367346938776 0.819801196340605 0.782535709784069 0.999999999999902 GO:0004190 aspartic-type endopeptidase activity 3/2088 36/18639 0.0833333333333333 0.74389367816092 0.784153989299378 0.999999999999902 GO:0016409 palmitoyltransferase activity 3/2088 36/18639 0.0833333333333333 0.74389367816092 0.784153989299378 0.999999999999902 GO:0002161 aminoacyl-tRNA editing activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0004535 poly(A)-specific ribonuclease activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0005035 death receptor activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0005542 folic acid binding 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0008253 5'-nucleotidase activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0008417 fucosyltransferase activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0017154 semaphorin receptor activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0030955 potassium ion binding 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0031432 titin binding 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0045159 myosin II binding 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0046974 histone H3K9 methyltransferase activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0046975 histone H3K36 methyltransferase activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0061459 L-arginine transmembrane transporter activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0070700 BMP receptor binding 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0071714 icosanoid transmembrane transporter activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0071837 HMG box domain binding 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0097157 pre-mRNA intronic binding 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/2088 13/18639 0.0769230769230769 0.686671087533157 0.786699532479549 0.999999999999902 GO:0000030 mannosyltransferase activity 2/2088 25/18639 0.08 0.714137931034483 0.787141274586614 0.999999999999902 GO:0015271 outward rectifier potassium channel activity 2/2088 25/18639 0.08 0.714137931034483 0.787141274586614 0.999999999999902 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/2088 25/18639 0.08 0.714137931034483 0.787141274586614 0.999999999999902 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/2088 25/18639 0.08 0.714137931034483 0.787141274586614 0.999999999999902 GO:0019707 protein-cysteine S-acyltransferase activity 2/2088 25/18639 0.08 0.714137931034483 0.787141274586614 0.999999999999902 GO:0140938 histone H3 methyltransferase activity 4/2088 47/18639 0.0851063829787234 0.759721203228173 0.787348724838879 0.999999999999902 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/2088 48/18639 0.0833333333333333 0.74389367816092 0.80105855472212 0.999999999999902 GO:0036121 double-stranded DNA helicase activity 4/2088 48/18639 0.0833333333333333 0.74389367816092 0.80105855472212 0.999999999999902 GO:0038187 pattern recognition receptor activity 4/2088 48/18639 0.0833333333333333 0.74389367816092 0.80105855472212 0.999999999999902 GO:0099106 ion channel regulator activity 15/2088 160/18639 0.09375 0.836880387931034 0.803479549096423 0.999999999999902 GO:0008143 poly(A) binding 2/2088 26/18639 0.0769230769230769 0.686671087533157 0.805267914720376 0.999999999999902 GO:0070006 metalloaminopeptidase activity 2/2088 26/18639 0.0769230769230769 0.686671087533157 0.805267914720376 0.999999999999902 GO:0042578 phosphoric ester hydrolase activity 36/2088 363/18639 0.0991735537190083 0.885294955827871 0.805933547917227 0.999999999999902 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/2088 70/18639 0.0857142857142857 0.765147783251231 0.810563435117653 0.999999999999902 GO:0016278 lysine N-methyltransferase activity 6/2088 70/18639 0.0857142857142857 0.765147783251231 0.810563435117653 0.999999999999902 GO:0004705 JUN kinase activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0005313 L-glutamate transmembrane transporter activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0005545 1-phosphatidylinositol binding 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0008174 mRNA methyltransferase activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0008191 metalloendopeptidase inhibitor activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0008474 palmitoyl-(protein) hydrolase activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0015386 potassium:proton antiporter activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0032454 histone H3K9 demethylase activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0034236 protein kinase A catalytic subunit binding 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0042043 neurexin family protein binding 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0046030 inositol trisphosphate phosphatase activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0061665 SUMO ligase activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0098599 palmitoyl hydrolase activity 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:1990825 sequence-specific mRNA binding 1/2088 14/18639 0.0714285714285714 0.63762315270936 0.810610805763276 0.999999999999902 GO:0035254 glutamate receptor binding 4/2088 49/18639 0.0816326530612245 0.728712174524982 0.814043083401312 0.999999999999902 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/2088 38/18639 0.0789473684210526 0.704741379310345 0.814394786979604 0.999999999999902 GO:0005104 fibroblast growth factor receptor binding 2/2088 27/18639 0.0740740740740741 0.661238825031928 0.82200686818034 0.999999999999902 GO:0005385 zinc ion transmembrane transporter activity 2/2088 27/18639 0.0740740740740741 0.661238825031928 0.82200686818034 0.999999999999902 GO:0035255 ionotropic glutamate receptor binding 2/2088 27/18639 0.0740740740740741 0.661238825031928 0.82200686818034 0.999999999999902 GO:0043178 alcohol binding 8/2088 92/18639 0.0869565217391304 0.77623688155922 0.822683372483979 0.999999999999902 GO:0004953 icosanoid receptor activity 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0005041 low-density lipoprotein particle receptor activity 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0005523 tropomyosin binding 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0008242 omega peptidase activity 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0008252 nucleotidase activity 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0015929 hexosaminidase activity 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0030553 cGMP binding 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0045504 dynein heavy chain binding 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0050780 dopamine receptor binding 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0061578 K63-linked deubiquitinase activity 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0140161 monocarboxylate:sodium symporter activity 1/2088 15/18639 0.0666666666666667 0.595114942528736 0.831842732612472 0.999999999999902 GO:0046875 ephrin receptor binding 2/2088 28/18639 0.0714285714285714 0.63762315270936 0.837441398656424 0.999999999999902 GO:0051393 alpha-actinin binding 2/2088 28/18639 0.0714285714285714 0.63762315270936 0.837441398656424 0.999999999999902 GO:0051959 dynein light intermediate chain binding 2/2088 28/18639 0.0714285714285714 0.63762315270936 0.837441398656424 0.999999999999902 GO:0141052 histone H3 demethylase activity 2/2088 28/18639 0.0714285714285714 0.63762315270936 0.837441398656424 0.999999999999902 GO:0004532 RNA exonuclease activity 3/2088 40/18639 0.075 0.669504310344828 0.840961048955168 0.999999999999902 GO:0015144 carbohydrate transmembrane transporter activity 3/2088 40/18639 0.075 0.669504310344828 0.840961048955168 0.999999999999902 GO:0016755 aminoacyltransferase activity 49/2088 496/18639 0.0987903225806452 0.881873957174638 0.846242832511316 0.999999999999902 GO:0008276 protein methyltransferase activity 8/2088 95/18639 0.0842105263157895 0.751724137931034 0.848439044131936 0.999999999999902 GO:0031491 nucleosome binding 6/2088 74/18639 0.0810810810810811 0.72378844361603 0.850131721035575 0.999999999999902 GO:0035064 methylated histone binding 6/2088 74/18639 0.0810810810810811 0.72378844361603 0.850131721035575 0.999999999999902 GO:0003688 DNA replication origin binding 1/2088 16/18639 0.0625 0.55792025862069 0.850695415940713 0.999999999999902 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/2088 16/18639 0.0625 0.55792025862069 0.850695415940713 0.999999999999902 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/2088 16/18639 0.0625 0.55792025862069 0.850695415940713 0.999999999999902 GO:0022841 potassium ion leak channel activity 1/2088 16/18639 0.0625 0.55792025862069 0.850695415940713 0.999999999999902 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/2088 16/18639 0.0625 0.55792025862069 0.850695415940713 0.999999999999902 GO:0022858 alanine transmembrane transporter activity 1/2088 16/18639 0.0625 0.55792025862069 0.850695415940713 0.999999999999902 GO:0070411 I-SMAD binding 1/2088 16/18639 0.0625 0.55792025862069 0.850695415940713 0.999999999999902 GO:0008234 cysteine-type peptidase activity 17/2088 187/18639 0.0909090909090909 0.811520376175549 0.850916637145956 0.999999999999902 GO:0005416 amino acid:monoatomic cation symporter activity 2/2088 29/18639 0.0689655172413793 0.61563614744352 0.851653537736428 0.999999999999902 GO:0051861 glycolipid binding 2/2088 29/18639 0.0689655172413793 0.61563614744352 0.851653537736428 0.999999999999902 GO:0106222 lncRNA binding 2/2088 29/18639 0.0689655172413793 0.61563614744352 0.851653537736428 0.999999999999902 GO:0001727 lipid kinase activity 3/2088 41/18639 0.0731707317073171 0.653174936921783 0.852964761267614 0.999999999999902 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/2088 41/18639 0.0731707317073171 0.653174936921783 0.852964761267614 0.999999999999902 GO:0042826 histone deacetylase binding 11/2088 127/18639 0.0866141732283465 0.77318083084442 0.855096148493194 0.999999999999902 GO:0005246 calcium channel regulator activity 4/2088 53/18639 0.0754716981132075 0.673715029277814 0.85917819419279 0.999999999999902 GO:0031490 chromatin DNA binding 11/2088 128/18639 0.0859375 0.767140355603448 0.86178971915676 0.999999999999902 GO:0031492 nucleosomal DNA binding 3/2088 42/18639 0.0714285714285714 0.63762315270936 0.864169315049289 0.999999999999902 GO:0001968 fibronectin binding 2/2088 30/18639 0.0666666666666667 0.595114942528736 0.86472331627059 0.999999999999902 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/2088 30/18639 0.0666666666666667 0.595114942528736 0.86472331627059 0.999999999999902 GO:0032452 histone demethylase activity 2/2088 30/18639 0.0666666666666667 0.595114942528736 0.86472331627059 0.999999999999902 GO:0033612 receptor serine/threonine kinase binding 2/2088 30/18639 0.0666666666666667 0.595114942528736 0.86472331627059 0.999999999999902 GO:0098918 structural constituent of synapse 2/2088 30/18639 0.0666666666666667 0.595114942528736 0.86472331627059 0.999999999999902 GO:0140034 methylation-dependent protein binding 6/2088 76/18639 0.0789473684210526 0.704741379310345 0.867228594898046 0.999999999999902 GO:0005092 GDP-dissociation inhibitor activity 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0016018 cyclosporin A binding 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0030169 low-density lipoprotein particle binding 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0030548 acetylcholine receptor regulator activity 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0032183 SUMO binding 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0045125 bioactive lipid receptor activity 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0045236 CXCR chemokine receptor binding 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0046965 nuclear retinoid X receptor binding 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0051787 misfolded protein binding 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0070492 oligosaccharide binding 1/2088 17/18639 0.0588235294117647 0.525101419878296 0.867435359640213 0.999999999999902 GO:0003925 G protein activity 4/2088 54/18639 0.0740740740740741 0.661238825031928 0.86888243145929 0.999999999999902 GO:0016798 hydrolase activity, acting on glycosyl bonds 11/2088 130/18639 0.0846153846153846 0.755338196286472 0.874439574545079 0.999999999999902 GO:0048156 tau protein binding 3/2088 43/18639 0.0697674418604651 0.622794707297514 0.874615089725052 0.999999999999902 GO:0004197 cysteine-type endopeptidase activity 7/2088 88/18639 0.0795454545454545 0.710080329153605 0.876168397593854 0.999999999999902 GO:0005184 neuropeptide hormone activity 2/2088 31/18639 0.0645161290322581 0.575917686318131 0.876728183254861 0.999999999999902 GO:0008327 methyl-CpG binding 2/2088 31/18639 0.0645161290322581 0.575917686318131 0.876728183254861 0.999999999999902 GO:0016411 acylglycerol O-acyltransferase activity 2/2088 31/18639 0.0645161290322581 0.575917686318131 0.876728183254861 0.999999999999902 GO:0047499 calcium-independent phospholipase A2 activity 2/2088 31/18639 0.0645161290322581 0.575917686318131 0.876728183254861 0.999999999999902 GO:0005372 water transmembrane transporter activity 1/2088 18/18639 0.0555555555555556 0.495929118773946 0.882299228669922 0.999999999999902 GO:0008525 phosphatidylcholine transporter activity 1/2088 18/18639 0.0555555555555556 0.495929118773946 0.882299228669922 0.999999999999902 GO:0015172 acidic amino acid transmembrane transporter activity 1/2088 18/18639 0.0555555555555556 0.495929118773946 0.882299228669922 0.999999999999902 GO:0022851 GABA-gated chloride ion channel activity 1/2088 18/18639 0.0555555555555556 0.495929118773946 0.882299228669922 0.999999999999902 GO:0030228 lipoprotein particle receptor activity 1/2088 18/18639 0.0555555555555556 0.495929118773946 0.882299228669922 0.999999999999902 GO:0034185 apolipoprotein binding 1/2088 18/18639 0.0555555555555556 0.495929118773946 0.882299228669922 0.999999999999902 GO:0050811 GABA receptor binding 1/2088 18/18639 0.0555555555555556 0.495929118773946 0.882299228669922 0.999999999999902 GO:0070064 proline-rich region binding 1/2088 18/18639 0.0555555555555556 0.495929118773946 0.882299228669922 0.999999999999902 GO:0099602 neurotransmitter receptor regulator activity 1/2088 18/18639 0.0555555555555556 0.495929118773946 0.882299228669922 0.999999999999902 GO:0001046 core promoter sequence-specific DNA binding 3/2088 44/18639 0.0681818181818182 0.608640282131661 0.884342093675384 0.999999999999902 GO:0043014 alpha-tubulin binding 3/2088 44/18639 0.0681818181818182 0.608640282131661 0.884342093675384 0.999999999999902 GO:0003774 cytoskeletal motor activity 13/2088 153/18639 0.0849673202614379 0.758479828713094 0.887254053028594 0.999999999999902 GO:0042910 xenobiotic transmembrane transporter activity 2/2088 32/18639 0.0625 0.55792025862069 0.887742579897412 0.999999999999902 GO:0047498 calcium-dependent phospholipase A2 activity 2/2088 32/18639 0.0625 0.55792025862069 0.887742579897412 0.999999999999902 GO:0140142 nucleocytoplasmic carrier activity 2/2088 32/18639 0.0625 0.55792025862069 0.887742579897412 0.999999999999902 GO:0160041 neuropeptide activity 2/2088 32/18639 0.0625 0.55792025862069 0.887742579897412 0.999999999999902 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 10/2088 122/18639 0.0819672131147541 0.731698699830413 0.889023956610745 0.999999999999902 GO:0003777 microtubule motor activity 5/2088 68/18639 0.0735294117647059 0.65637677484787 0.891098730660757 0.999999999999902 GO:0032934 sterol binding 5/2088 68/18639 0.0735294117647059 0.65637677484787 0.891098730660757 0.999999999999902 GO:0003756 protein disulfide isomerase activity 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0004890 GABA-A receptor activity 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0005520 insulin-like growth factor binding 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0022821 solute:potassium antiporter activity 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0022840 leak channel activity 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0022842 narrow pore channel activity 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0030506 ankyrin binding 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0042800 histone H3K4 methyltransferase activity 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0050145 nucleoside monophosphate kinase activity 1/2088 19/18639 0.0526315789473684 0.469827586206897 0.89549718852907 0.999999999999902 GO:0015103 inorganic anion transmembrane transporter activity 14/2088 165/18639 0.0848484848484849 0.757419017763845 0.895529678672715 0.999999999999902 GO:0016757 glycosyltransferase activity 24/2088 267/18639 0.0898876404494382 0.802402169701666 0.897867424879559 0.999999999999902 GO:0016279 protein-lysine N-methyltransferase activity 5/2088 69/18639 0.072463768115942 0.646864067966017 0.898256118283647 0.999999999999902 GO:0008194 UDP-glycosyltransferase activity 12/2088 145/18639 0.0827586206896552 0.738763376932223 0.899426944983196 0.999999999999902 GO:0016758 hexosyltransferase activity 17/2088 197/18639 0.0862944162436548 0.770326448450901 0.900730760232865 0.999999999999902 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 46/2088 484/18639 0.0950413223140496 0.84840766600171 0.900755297746197 0.999999999999902 GO:0008408 3'-5' exonuclease activity 4/2088 58/18639 0.0689655172413793 0.61563614744352 0.902141431310437 0.999999999999902 GO:0017116 single-stranded DNA helicase activity 4/2088 58/18639 0.0689655172413793 0.61563614744352 0.902141431310437 0.999999999999902 GO:0005253 monoatomic anion channel activity 8/2088 103/18639 0.0776699029126214 0.693337797120857 0.902691972515745 0.999999999999902 GO:0044325 transmembrane transporter binding 11/2088 136/18639 0.0808823529411765 0.722014452332657 0.906873603869971 0.999999999999902 GO:0051427 hormone receptor binding 2/2088 34/18639 0.0588235294117647 0.525101419878296 0.907081003337422 0.999999999999902 GO:0090482 vitamin transmembrane transporter activity 2/2088 34/18639 0.0588235294117647 0.525101419878296 0.907081003337422 0.999999999999902 GO:0046982 protein heterodimerization activity 34/2088 369/18639 0.0921409214092141 0.822516587234838 0.907140099342199 0.999999999999902 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/2088 20/18639 0.05 0.446336206896552 0.907215871147293 0.999999999999902 GO:0010851 cyclase regulator activity 1/2088 20/18639 0.05 0.446336206896552 0.907215871147293 0.999999999999902 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/2088 20/18639 0.05 0.446336206896552 0.907215871147293 0.999999999999902 GO:0030627 pre-mRNA 5'-splice site binding 1/2088 20/18639 0.05 0.446336206896552 0.907215871147293 0.999999999999902 GO:0042288 MHC class I protein binding 1/2088 20/18639 0.05 0.446336206896552 0.907215871147293 0.999999999999902 GO:0140939 histone H4 methyltransferase activity 1/2088 20/18639 0.05 0.446336206896552 0.907215871147293 0.999999999999902 GO:0030246 carbohydrate binding 25/2088 280/18639 0.0892857142857143 0.7970289408867 0.908444603630405 0.999999999999902 GO:0017124 SH3 domain binding 9/2088 115/18639 0.0782608695652174 0.698613193403298 0.908858147774542 0.999999999999902 GO:0004879 nuclear receptor activity 4/2088 59/18639 0.0677966101694915 0.605201636469901 0.909193424266529 0.999999999999902 GO:0070888 E-box binding 4/2088 59/18639 0.0677966101694915 0.605201636469901 0.909193424266529 0.999999999999902 GO:0061749 forked DNA-dependent helicase activity 3/2088 47/18639 0.0638297872340425 0.56979090242113 0.909599639557933 0.999999999999902 GO:0140359 ABC-type transporter activity 3/2088 47/18639 0.0638297872340425 0.56979090242113 0.909599639557933 0.999999999999902 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/2088 47/18639 0.0638297872340425 0.56979090242113 0.909599639557933 0.999999999999902 GO:0015294 solute:monoatomic cation symporter activity 9/2088 116/18639 0.0775862068965517 0.69259066587396 0.913798991110592 0.999999999999902 GO:0030165 PDZ domain binding 6/2088 83/18639 0.072289156626506 0.645305359368509 0.914761262272854 0.999999999999902 GO:0004623 phospholipase A2 activity 2/2088 35/18639 0.0571428571428571 0.510098522167488 0.915536692583427 0.999999999999902 GO:0005343 organic acid:sodium symporter activity 2/2088 35/18639 0.0571428571428571 0.510098522167488 0.915536692583427 0.999999999999902 GO:0140566 histone reader activity 2/2088 35/18639 0.0571428571428571 0.510098522167488 0.915536692583427 0.999999999999902 GO:0098531 ligand-modulated transcription factor activity 4/2088 60/18639 0.0666666666666667 0.595114942528736 0.915789851754245 0.999999999999902 GO:0009378 four-way junction helicase activity 3/2088 48/18639 0.0625 0.55792025862069 0.916835711880321 0.999999999999902 GO:0043138 3'-5' DNA helicase activity 3/2088 48/18639 0.0625 0.55792025862069 0.916835711880321 0.999999999999902 GO:0008509 monoatomic anion transmembrane transporter activity 12/2088 149/18639 0.0805369127516778 0.718930803054848 0.917513509895663 0.999999999999902 GO:0008373 sialyltransferase activity 1/2088 21/18639 0.0476190476190476 0.42508210180624 0.917621008965889 0.999999999999902 GO:0015125 bile acid transmembrane transporter activity 1/2088 21/18639 0.0476190476190476 0.42508210180624 0.917621008965889 0.999999999999902 GO:0015174 basic amino acid transmembrane transporter activity 1/2088 21/18639 0.0476190476190476 0.42508210180624 0.917621008965889 0.999999999999902 GO:0061891 calcium ion sensor activity 1/2088 21/18639 0.0476190476190476 0.42508210180624 0.917621008965889 0.999999999999902 GO:0070182 DNA polymerase binding 1/2088 21/18639 0.0476190476190476 0.42508210180624 0.917621008965889 0.999999999999902 GO:0072542 protein phosphatase activator activity 1/2088 21/18639 0.0476190476190476 0.42508210180624 0.917621008965889 0.999999999999902 GO:0008013 beta-catenin binding 8/2088 106/18639 0.0754716981132075 0.673715029277814 0.918296085013516 0.999999999999902 GO:0001216 DNA-binding transcription activator activity 46/2088 491/18639 0.0936863543788187 0.836312241028162 0.918657521715636 0.999999999999902 GO:0140767 enzyme-substrate adaptor activity 11/2088 139/18639 0.079136690647482 0.706431406598859 0.92026858992529 0.999999999999902 GO:0005004 GPI-linked ephrin receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0005008 hepatocyte growth factor receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0005009 insulin receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0005011 macrophage colony-stimulating factor receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0005020 stem cell factor receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0008288 boss receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0036332 placental growth factor receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0038062 protein tyrosine kinase collagen receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0060175 brain-derived neurotrophic factor receptor activity 3/2088 49/18639 0.0612244897959184 0.546534130893737 0.923539578955039 0.999999999999902 GO:0005243 gap junction channel activity 1/2088 22/18639 0.0454545454545455 0.405760188087774 0.926859774315509 0.999999999999902 GO:0008970 phospholipase A1 activity 1/2088 22/18639 0.0454545454545455 0.405760188087774 0.926859774315509 0.999999999999902 GO:0016881 acid-amino acid ligase activity 1/2088 22/18639 0.0454545454545455 0.405760188087774 0.926859774315509 0.999999999999902 GO:0031683 G-protein beta/gamma-subunit complex binding 1/2088 22/18639 0.0454545454545455 0.405760188087774 0.926859774315509 0.999999999999902 GO:0050321 tau-protein kinase activity 1/2088 22/18639 0.0454545454545455 0.405760188087774 0.926859774315509 0.999999999999902 GO:0061133 endopeptidase activator activity 1/2088 22/18639 0.0454545454545455 0.405760188087774 0.926859774315509 0.999999999999902 GO:0140517 protein-RNA adaptor activity 1/2088 22/18639 0.0454545454545455 0.405760188087774 0.926859774315509 0.999999999999902 GO:0003678 DNA helicase activity 5/2088 74/18639 0.0675675675675676 0.603157036346691 0.928223642618323 0.999999999999902 GO:0046906 tetrapyrrole binding 12/2088 152/18639 0.0789473684210526 0.704741379310345 0.929210042339799 0.999999999999902 GO:0005006 epidermal growth factor receptor activity 3/2088 50/18639 0.06 0.535603448275862 0.929744835701794 0.999999999999902 GO:0005007 fibroblast growth factor receptor activity 3/2088 50/18639 0.06 0.535603448275862 0.929744835701794 0.999999999999902 GO:0005017 platelet-derived growth factor receptor activity 3/2088 50/18639 0.06 0.535603448275862 0.929744835701794 0.999999999999902 GO:0005019 platelet-derived growth factor beta-receptor activity 3/2088 50/18639 0.06 0.535603448275862 0.929744835701794 0.999999999999902 GO:0023023 MHC protein complex binding 2/2088 37/18639 0.0540540540540541 0.482525629077353 0.930322928560266 0.999999999999902 GO:0042805 actinin binding 2/2088 37/18639 0.0540540540540541 0.482525629077353 0.930322928560266 0.999999999999902 GO:0020037 heme binding 11/2088 142/18639 0.0774647887323944 0.691506799417193 0.931992941797892 0.999999999999902 GO:0005158 insulin receptor binding 1/2088 23/18639 0.0434782608695652 0.38811844077961 0.935062857047916 0.999999999999902 GO:0016917 GABA receptor activity 1/2088 23/18639 0.0434782608695652 0.38811844077961 0.935062857047916 0.999999999999902 GO:0031681 G-protein beta-subunit binding 1/2088 23/18639 0.0434782608695652 0.38811844077961 0.935062857047916 0.999999999999902 GO:0070577 lysine-acetylated histone binding 1/2088 23/18639 0.0434782608695652 0.38811844077961 0.935062857047916 0.999999999999902 GO:0099186 structural constituent of postsynapse 1/2088 23/18639 0.0434782608695652 0.38811844077961 0.935062857047916 0.999999999999902 GO:0005010 insulin-like growth factor receptor activity 3/2088 51/18639 0.0588235294117647 0.525101419878296 0.935483643898648 0.999999999999902 GO:0005021 vascular endothelial growth factor receptor activity 3/2088 51/18639 0.0588235294117647 0.525101419878296 0.935483643898648 0.999999999999902 GO:0005030 neurotrophin receptor activity 3/2088 51/18639 0.0588235294117647 0.525101419878296 0.935483643898648 0.999999999999902 GO:0000146 microfilament motor activity 2/2088 38/18639 0.0526315789473684 0.469827586206897 0.936763380870303 0.999999999999902 GO:0005501 retinoid binding 2/2088 38/18639 0.0526315789473684 0.469827586206897 0.936763380870303 0.999999999999902 GO:0019840 isoprenoid binding 2/2088 38/18639 0.0526315789473684 0.469827586206897 0.936763380870303 0.999999999999902 GO:0042887 amide transmembrane transporter activity 2/2088 38/18639 0.0526315789473684 0.469827586206897 0.936763380870303 0.999999999999902 GO:0043531 ADP binding 2/2088 38/18639 0.0526315789473684 0.469827586206897 0.936763380870303 0.999999999999902 GO:0030215 semaphorin receptor binding 1/2088 24/18639 0.0416666666666667 0.37194683908046 0.942346309695314 0.999999999999902 GO:0030552 cAMP binding 1/2088 24/18639 0.0416666666666667 0.37194683908046 0.942346309695314 0.999999999999902 GO:0035035 histone acetyltransferase binding 1/2088 24/18639 0.0416666666666667 0.37194683908046 0.942346309695314 0.999999999999902 GO:0050431 transforming growth factor beta binding 1/2088 24/18639 0.0416666666666667 0.37194683908046 0.942346309695314 0.999999999999902 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/2088 24/18639 0.0416666666666667 0.37194683908046 0.942346309695314 0.999999999999902 GO:0140033 acetylation-dependent protein binding 1/2088 24/18639 0.0416666666666667 0.37194683908046 0.942346309695314 0.999999999999902 GO:0038024 cargo receptor activity 4/2088 65/18639 0.0615384615384615 0.549336870026525 0.942750862612006 0.999999999999902 GO:0005319 lipid transporter activity 14/2088 178/18639 0.0786516853932584 0.702101898488958 0.943941998935759 0.999999999999902 GO:0005003 ephrin receptor activity 3/2088 53/18639 0.0566037735849057 0.50528627195836 0.94568320802261 0.999999999999902 GO:0005005 transmembrane-ephrin receptor activity 3/2088 53/18639 0.0566037735849057 0.50528627195836 0.94568320802261 0.999999999999902 GO:0038064 collagen receptor activity 3/2088 53/18639 0.0566037735849057 0.50528627195836 0.94568320802261 0.999999999999902 GO:0003707 nuclear steroid receptor activity 1/2088 25/18639 0.04 0.357068965517241 0.948813186158176 0.999999999999902 GO:0005537 D-mannose binding 1/2088 25/18639 0.04 0.357068965517241 0.948813186158176 0.999999999999902 GO:0008139 nuclear localization sequence binding 1/2088 25/18639 0.04 0.357068965517241 0.948813186158176 0.999999999999902 GO:0017056 structural constituent of nuclear pore 1/2088 25/18639 0.04 0.357068965517241 0.948813186158176 0.999999999999902 GO:0019211 phosphatase activator activity 1/2088 25/18639 0.04 0.357068965517241 0.948813186158176 0.999999999999902 GO:0016887 ATP hydrolysis activity 37/2088 417/18639 0.0887290167865707 0.792059455883569 0.949363496730626 0.999999999999902 GO:0015370 solute:sodium symporter activity 5/2088 79/18639 0.0632911392405063 0.564982540375382 0.950061086669358 0.999999999999902 GO:0140463 chromatin-protein adaptor activity 3/2088 54/18639 0.0555555555555556 0.495929118773946 0.950200900761629 0.999999999999902 GO:0001530 lipopolysaccharide binding 2/2088 41/18639 0.0487804878048781 0.435449957947855 0.95286039464805 0.999999999999902 GO:0017080 sodium channel regulator activity 2/2088 41/18639 0.0487804878048781 0.435449957947855 0.95286039464805 0.999999999999902 GO:0015291 secondary active transmembrane transporter activity 24/2088 287/18639 0.0836236933797909 0.746485642196324 0.953319689662627 0.999999999999902 GO:0005227 calcium-activated cation channel activity 1/2088 26/18639 0.0384615384615385 0.343335543766578 0.954554997015688 0.999999999999902 GO:0019865 immunoglobulin binding 1/2088 26/18639 0.0384615384615385 0.343335543766578 0.954554997015688 0.999999999999902 GO:0052742 phosphatidylinositol kinase activity 1/2088 26/18639 0.0384615384615385 0.343335543766578 0.954554997015688 0.999999999999902 GO:1990841 promoter-specific chromatin binding 4/2088 68/18639 0.0588235294117647 0.525101419878296 0.95487984656512 0.999999999999902 GO:0042393 histone binding 20/2088 247/18639 0.0809716599190283 0.722811671087533 0.956629565563865 0.999999999999902 GO:0001618 virus receptor activity 5/2088 81/18639 0.0617283950617284 0.551032354193274 0.95695983056275 0.999999999999902 GO:0015101 organic cation transmembrane transporter activity 5/2088 81/18639 0.0617283950617284 0.551032354193274 0.95695983056275 0.999999999999902 GO:0008514 organic anion transmembrane transporter activity 22/2088 269/18639 0.0817843866171004 0.730066658120754 0.958576892825259 0.999999999999902 GO:0005044 scavenger receptor activity 1/2088 27/18639 0.037037037037037 0.330619412515964 0.959653001970894 0.999999999999902 GO:0008395 steroid hydroxylase activity 1/2088 27/18639 0.037037037037037 0.330619412515964 0.959653001970894 0.999999999999902 GO:0023026 MHC class II protein complex binding 1/2088 27/18639 0.037037037037037 0.330619412515964 0.959653001970894 0.999999999999902 GO:0140272 exogenous protein binding 5/2088 82/18639 0.0609756097560976 0.544312447434819 0.960072021220105 0.999999999999902 GO:0019789 SUMO transferase activity 1/2088 28/18639 0.0357142857142857 0.31881157635468 0.964179357649207 0.999999999999902 GO:0045499 chemorepellent activity 1/2088 28/18639 0.0357142857142857 0.31881157635468 0.964179357649207 0.999999999999902 GO:0050698 proteoglycan sulfotransferase activity 1/2088 28/18639 0.0357142857142857 0.31881157635468 0.964179357649207 0.999999999999902 GO:0005496 steroid binding 7/2088 108/18639 0.0648148148148148 0.578583971902937 0.965200374457575 0.999999999999902 GO:0030695 GTPase regulator activity 43/2088 489/18639 0.0879345603271984 0.784967562231154 0.966253469912238 0.999999999999902 GO:0042379 chemokine receptor binding 4/2088 72/18639 0.0555555555555556 0.495929118773946 0.96737869018061 0.999999999999902 GO:0060589 nucleoside-triphosphatase regulator activity 43/2088 490/18639 0.0877551020408163 0.783365587614356 0.967400259442764 0.999999999999902 GO:0015108 chloride transmembrane transporter activity 8/2088 121/18639 0.0661157024793388 0.590196637218581 0.967966053897676 0.999999999999902 GO:0099604 ligand-gated calcium channel activity 1/2088 29/18639 0.0344827586206897 0.30781807372176 0.968198136931807 0.999999999999902 GO:0008009 chemokine activity 2/2088 45/18639 0.0444444444444444 0.396743295019157 0.968324551519949 0.999999999999902 GO:0140303 intramembrane lipid transporter activity 2/2088 45/18639 0.0444444444444444 0.396743295019157 0.968324551519949 0.999999999999902 GO:0005249 voltage-gated potassium channel activity 6/2088 98/18639 0.0612244897959184 0.546534130893737 0.969773882063353 0.999999999999902 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/2088 60/18639 0.05 0.446336206896552 0.970722615308388 0.999999999999902 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/2088 60/18639 0.05 0.446336206896552 0.970722615308388 0.999999999999902 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/2088 46/18639 0.0434782608695652 0.38811844077961 0.971348558876208 0.999999999999902 GO:0022839 monoatomic ion-gated channel activity 1/2088 30/18639 0.0333333333333333 0.297557471264368 0.971766234195987 0.999999999999902 GO:0031624 ubiquitin conjugating enzyme binding 1/2088 30/18639 0.0333333333333333 0.297557471264368 0.971766234195987 0.999999999999902 GO:0008081 phosphoric diester hydrolase activity 5/2088 87/18639 0.0574712643678161 0.5130301228696 0.972753285865426 0.999999999999902 GO:0005267 potassium channel activity 8/2088 124/18639 0.0645161290322581 0.575917686318131 0.973735980777957 0.999999999999902 GO:0099095 ligand-gated monoatomic anion channel activity 2/2088 47/18639 0.0425531914893617 0.379860601614087 0.974092955290354 0.999999999999902 GO:0017147 Wnt-protein binding 1/2088 31/18639 0.032258064516129 0.287958843159066 0.974934169227357 0.999999999999902 GO:0072349 modified amino acid transmembrane transporter activity 1/2088 31/18639 0.032258064516129 0.287958843159066 0.974934169227357 0.999999999999902 GO:0008083 growth factor activity 11/2088 162/18639 0.0679012345679012 0.606135589612601 0.97842840150022 0.999999999999902 GO:0005126 cytokine receptor binding 21/2088 275/18639 0.0763636363636364 0.681677115987461 0.980835137197183 0.999999999999902 GO:0048020 CCR chemokine receptor binding 2/2088 50/18639 0.04 0.357068965517241 0.980885154767618 0.999999999999902 GO:0015020 glucuronosyltransferase activity 1/2088 34/18639 0.0294117647058824 0.262550709939148 0.982461021747544 0.999999999999902 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/2088 34/18639 0.0294117647058824 0.262550709939148 0.982461021747544 0.999999999999902 GO:0019825 oxygen binding 1/2088 34/18639 0.0294117647058824 0.262550709939148 0.982461021747544 0.999999999999902 GO:0005048 signal sequence binding 2/2088 51/18639 0.0392156862745098 0.350067613252197 0.982738277660229 0.999999999999902 GO:0005272 sodium channel activity 2/2088 51/18639 0.0392156862745098 0.350067613252197 0.982738277660229 0.999999999999902 GO:0005506 iron ion binding 10/2088 154/18639 0.0649350649350649 0.579657411553963 0.982779832774148 0.999999999999902 GO:0042562 hormone binding 5/2088 94/18639 0.0531914893617021 0.474825752017608 0.984322313128361 0.999999999999902 GO:0016500 protein-hormone receptor activity 3/2088 67/18639 0.0447761194029851 0.399704065877509 0.984547197613652 0.999999999999902 GO:0019955 cytokine binding 9/2088 144/18639 0.0625 0.55792025862069 0.984736906336333 0.999999999999902 GO:0008146 sulfotransferase activity 2/2088 53/18639 0.0377358490566038 0.336857514638907 0.985935287239965 0.999999999999902 GO:0017046 peptide hormone binding 2/2088 53/18639 0.0377358490566038 0.336857514638907 0.985935287239965 0.999999999999902 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/2088 36/18639 0.0277777777777778 0.247964559386973 0.986176935726468 0.999999999999902 GO:0005096 GTPase activator activity 20/2088 271/18639 0.0738007380073801 0.658798829367604 0.986421807189997 0.999999999999902 GO:0015293 symporter activity 9/2088 146/18639 0.0616438356164384 0.550277515351913 0.986661497600878 0.999999999999902 GO:0004222 metalloendopeptidase activity 6/2088 110/18639 0.0545454545454545 0.486912225705329 0.987706500654146 0.999999999999902 GO:0030551 cyclic nucleotide binding 1/2088 37/18639 0.027027027027027 0.241262814538677 0.987728435925529 0.999999999999902 GO:0043394 proteoglycan binding 1/2088 37/18639 0.027027027027027 0.241262814538677 0.987728435925529 0.999999999999902 GO:0004527 exonuclease activity 4/2088 84/18639 0.0476190476190476 0.42508210180624 0.98816858724314 0.999999999999902 GO:0015079 potassium ion transmembrane transporter activity 10/2088 160/18639 0.0625 0.55792025862069 0.988350029383418 0.999999999999902 GO:0005109 frizzled binding 1/2088 38/18639 0.0263157894736842 0.234913793103448 0.989105869845941 0.999999999999902 GO:0005261 monoatomic cation channel activity 26/2088 341/18639 0.0762463343108504 0.680629992921428 0.989291974052679 0.999999999999902 GO:0005518 collagen binding 3/2088 72/18639 0.0416666666666667 0.37194683908046 0.990315754631505 0.999999999999902 GO:0046943 carboxylic acid transmembrane transporter activity 12/2088 188/18639 0.0638297872340425 0.56979090242113 0.991178885386474 0.999999999999902 GO:0061980 regulatory RNA binding 2/2088 58/18639 0.0344827586206897 0.30781807372176 0.991610982318475 0.999999999999902 GO:0005342 organic acid transmembrane transporter activity 12/2088 189/18639 0.0634920634920635 0.566776135741653 0.991722520625305 0.999999999999902 GO:0008227 G protein-coupled amine receptor activity 1/2088 41/18639 0.024390243902439 0.217724978973928 0.99237828392399 0.999999999999902 GO:0042287 MHC protein binding 1/2088 41/18639 0.024390243902439 0.217724978973928 0.99237828392399 0.999999999999902 GO:0036002 pre-mRNA binding 2/2088 59/18639 0.0338983050847458 0.30260081823495 0.992440280746117 0.999999999999902 GO:0003725 double-stranded RNA binding 3/2088 75/18639 0.04 0.357068965517241 0.992711475455067 0.999999999999902 GO:0016298 lipase activity 7/2088 130/18639 0.0538461538461538 0.48066976127321 0.992910316884496 0.999999999999902 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 11/2088 181/18639 0.0607734806629834 0.542508096780339 0.993592594631408 0.999999999999902 GO:0001664 G protein-coupled receptor binding 21/2088 297/18639 0.0707070707070707 0.631182514803204 0.993809417680252 0.999999999999902 GO:0005245 voltage-gated calcium channel activity 1/2088 43/18639 0.0232558139534884 0.207598235765838 0.993993638422863 0.999999999999902 GO:0015179 L-amino acid transmembrane transporter activity 2/2088 62/18639 0.032258064516129 0.287958843159066 0.994475397117352 0.999999999999902 GO:0019199 transmembrane receptor protein kinase activity 3/2088 78/18639 0.0384615384615385 0.343335543766578 0.994528947021783 0.999999999999902 GO:0030547 signaling receptor inhibitor activity 1/2088 44/18639 0.0227272727272727 0.202880094043887 0.99466804598218 0.999999999999902 GO:0008201 heparin binding 10/2088 172/18639 0.0581395348837209 0.518995589414595 0.994839481963627 0.999999999999902 GO:0022824 transmitter-gated monoatomic ion channel activity 2/2088 63/18639 0.0317460317460317 0.283388067870826 0.995025923226903 0.999999999999902 GO:0022835 transmitter-gated channel activity 2/2088 63/18639 0.0317460317460317 0.283388067870826 0.995025923226903 0.999999999999902 GO:0004620 phospholipase activity 5/2088 109/18639 0.0458715596330275 0.40948275862069 0.995479080294764 0.999999999999902 GO:0005216 monoatomic ion channel activity 34/2088 448/18639 0.0758928571428571 0.677474599753695 0.995985079991615 0.999999999999902 GO:0015081 sodium ion transmembrane transporter activity 9/2088 164/18639 0.0548780487804878 0.489881202691337 0.996248085599494 0.999999999999902 GO:0030594 neurotransmitter receptor activity 4/2088 97/18639 0.0412371134020619 0.368112335584785 0.996274717804063 0.999999999999902 GO:0005254 chloride channel activity 3/2088 83/18639 0.036144578313253 0.322652679684254 0.996626215746952 0.999999999999902 GO:0008188 neuropeptide receptor activity 1/2088 48/18639 0.0208333333333333 0.18597341954023 0.996689020118795 0.999999999999902 GO:0005201 extracellular matrix structural constituent 9/2088 168/18639 0.0535714285714286 0.47821736453202 0.99720452158978 0.999999999999902 GO:0098960 postsynaptic neurotransmitter receptor activity 2/2088 69/18639 0.0289855072463768 0.258745627186407 0.997361323943158 0.999999999999902 GO:0022843 voltage-gated monoatomic cation channel activity 7/2088 143/18639 0.048951048951049 0.436972510248372 0.997427599575328 0.999999999999902 GO:0015171 amino acid transmembrane transporter activity 4/2088 102/18639 0.0392156862745098 0.350067613252197 0.997642179813743 0.999999999999902 GO:0005262 calcium channel activity 6/2088 131/18639 0.0458015267175573 0.408857594103712 0.997733821380111 0.999999999999902 GO:0005244 voltage-gated monoatomic ion channel activity 9/2088 173/18639 0.0520231213872832 0.464396053418378 0.99807598300233 0.999999999999902 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/2088 53/18639 0.0188679245283019 0.168428757319453 0.998175147677958 0.999999999999902 GO:0042277 peptide binding 15/2088 249/18639 0.0602409638554217 0.537754466140424 0.998258997654815 0.999999999999902 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/2088 73/18639 0.0273972602739726 0.24456778460085 0.998277023892169 0.999999999999902 GO:0022832 voltage-gated channel activity 9/2088 175/18639 0.0514285714285714 0.459088669950739 0.998345905022444 0.999999999999902 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/2088 56/18639 0.0178571428571429 0.15940578817734 0.998723693588007 0.999999999999902 GO:0004896 cytokine receptor activity 3/2088 96/18639 0.03125 0.278960129310345 0.999065895159486 0.999999999999902 GO:0005179 hormone activity 5/2088 132/18639 0.0378787878787879 0.338133490073145 0.999406141180916 0.999999999999902 GO:0015085 calcium ion transmembrane transporter activity 6/2088 147/18639 0.0408163265306122 0.364356087262491 0.99942260605744 0.999999999999902 GO:0099094 ligand-gated monoatomic cation channel activity 5/2088 136/18639 0.0367647058823529 0.328188387423935 0.999587875156807 0.999999999999902 GO:0008236 serine-type peptidase activity 9/2088 194/18639 0.0463917525773196 0.414126377532883 0.999623931647827 0.999999999999902 GO:0004497 monooxygenase activity 3/2088 106/18639 0.0283018867924528 0.25264313597918 0.999659865830929 0.999999999999902 GO:0017171 serine hydrolase activity 9/2088 198/18639 0.0454545454545455 0.405760188087774 0.999727319444829 0.999999999999902 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/2088 91/18639 0.021978021978022 0.196191739295188 0.999754037828501 0.999999999999902 GO:0005539 glycosaminoglycan binding 12/2088 242/18639 0.0495867768595041 0.442647477913936 0.999798436188194 0.999999999999902 GO:0005178 integrin binding 6/2088 161/18639 0.0372670807453416 0.332672949239666 0.999833135111726 0.999999999999902 GO:0005125 cytokine activity 11/2088 234/18639 0.047008547008547 0.419632331270262 0.999865649766889 0.999999999999902 GO:0003730 mRNA 3'-UTR binding 13/2088 262/18639 0.049618320610687 0.442929060279021 0.999880128627342 0.999999999999902 GO:0022836 gated channel activity 17/2088 318/18639 0.0534591194968553 0.477214812405118 0.999914153954227 0.999999999999902 GO:0015276 ligand-gated monoatomic ion channel activity 7/2088 186/18639 0.0376344086021505 0.335951983685577 0.99993231964387 0.999999999999902 GO:0008528 G protein-coupled peptide receptor activity 3/2088 122/18639 0.0245901639344262 0.219509609949124 0.99993459491915 0.999999999999902 GO:0022834 ligand-gated channel activity 7/2088 188/18639 0.0372340425531915 0.332378026412326 0.999943342665294 0.999999999999902 GO:0004252 serine-type endopeptidase activity 6/2088 176/18639 0.0340909090909091 0.304320141065831 0.999957560563847 0.999999999999902 GO:0004175 endopeptidase activity 23/2088 405/18639 0.0567901234567901 0.506949765857812 0.999963088812499 0.999999999999902 GO:0001653 peptide receptor activity 3/2088 128/18639 0.0234375 0.209220096982759 0.99996505954698 0.999999999999902 GO:0046873 metal ion transmembrane transporter activity 25/2088 450/18639 0.0555555555555556 0.495929118773946 0.999990543584906 0.999999999999902 GO:0140375 immune receptor activity 3/2088 156/18639 0.0192307692307692 0.171667771883289 0.999998217517541 0.999999999999902 GO:0045182 translation regulator activity 14/2088 356/18639 0.0393258426966292 0.351050949244479 0.999999808085935 0.999999999999902 GO:0030371 translation repressor activity 4/2088 329/18639 0.0121580547112462 0.108531600461168 0.999999999999902 0.999999999999902