category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	4/20	138/9376	13.5884057971014	MT-ATP8/MT-ND5/MT-ND4L/MT-ATP6	6.88774131779074
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	5/20	275/9376	8.52363636363636	MT-ATP8/MT-ND5/MT-ND4L/HSPA1B/MT-ATP6	5.85470633179584
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	4/20	205/9376	9.14731707317073	MT-ATP8/MT-ND5/MT-ND4L/MT-ATP6	5.45304060466582
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	4/20	227/9376	8.26079295154185	MT-ATP8/MT-ND5/MT-ND4L/MT-ATP6	5.11994972974011
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	4/20	235/9376	7.97957446808511	MT-ATP8/MT-ND5/MT-ND4L/MT-ATP6	5.00981341579809
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/20	268/9376	6.99701492537313	MT-ATP8/MT-ND5/MT-ND4L/MT-ATP6	4.60517931431872
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	4/20	308/9376	6.08831168831169	MT-ATP8/MT-ND5/MT-ND4L/MT-ATP6	4.19806190532165
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	4/20	368/9376	5.09565217391304	MT-ATP8/MT-ND5/MT-ND4L/MT-ATP6	3.70585409775956
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	4/20	388/9376	4.83298969072165	MT-ATP8/MT-ND5/MT-ND4L/MT-ATP6	3.5651475741652
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/20	82/9376	11.4341463414634	HLA-DRB1/HSPA1B	4.38750925020208
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	4/20	480/9376	3.90666666666667	MT-ATP8/MT-ND5/MT-ND4L/MT-ATP6	3.02255346183628
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/20	99/9376	9.47070707070707	HLA-DRB1/DEFB1	3.91731965788202
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/20	100/9376	9.376	CXCL14/TNFSF10	3.89324583938533
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/20	112/9376	8.37142857142857	HLA-DRB1/HSPA1B	3.62841479577084
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/20	133/9376	7.04962406015038	PLCG2/TNFSF10	3.24865251668632
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/20	149/9376	6.29261744966443	MT-ND5/MT-ND4L	3.01084853101732
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/20	160/9376	5.86	CDH2/HLA-DRB1	2.86668884848708
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/20	173/9376	5.41965317919075	HLA-DRB1/TNFSF10	2.71270183126548
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	2/20	193/9376	4.8580310880829	PLCG2/CXCL14	2.50384600444325
Human Diseases	Immune disease	hsa05310	Asthma	1/20	32/9376	14.65	HLA-DRB1	3.57599378323606
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/20	205/9376	4.57365853658537	PLCG2/HLA-DRB1	2.39186776851765
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/20	37/9376	12.6702702702703	PAX8	3.28841876449314
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/20	216/9376	4.34074074074074	TNFSF10/HSPA1B	2.29655812430727
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/20	39/9376	12.0205128205128	HLA-DRB1	3.18849659619102
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/20	42/9376	11.1619047619048	SAT1	3.0515563689665
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/20	44/9376	10.6545454545455	HLA-DRB1	2.96774330711014
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/20	45/9376	10.4177777777778	DEFB1	2.92783184562285
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/20	45/9376	10.4177777777778	HLA-DRB1	2.92783184562285
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/20	50/9376	9.376	SAT1	2.74555086965988
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/20	50/9376	9.376	HLA-DRB1	2.74555086965988
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/20	51/9376	9.1921568627451	PLCG2	2.71215469355708
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/20	54/9376	8.68148148148148	HLA-DRB1	2.61723577458828
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/20	56/9376	8.37142857142857	HSPA1B	2.55795705191804
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/20	60/9376	7.81333333333333	PLCG2	2.44780068209057
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/20	62/9376	7.56129032258064	HSPA1B	2.39647284447153
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/20	298/9376	3.14630872483221	CXCL14/TNFSF10	1.74084764088817
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/20	66/9376	7.1030303030303	HLA-DRB1	2.30037258441586
NA	NA	hsa04517	IgSF CAM signaling	2/20	299/9376	3.13578595317726	CDH2/PLCG2	1.73531244657407
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/20	69/9376	6.79420289855072	PLCG2	2.23341236858006
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/20	70/9376	6.69714285714286	HLA-DRB1	2.21197459653116
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/20	71/9376	6.60281690140845	PLCG2	2.19095241438927
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/20	73/9376	6.42191780821918	PLCG2	2.15009861182797
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/20	75/9376	6.25066666666667	PAX8	2.11074508848556
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/20	76/9376	6.16842105263158	PLCG2	2.09160050570481
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/20	78/9376	6.01025641025641	PLCG2	2.05431961193387
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/20	78/9376	6.01025641025641	HLA-DRB1	2.05431961193387
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/20	79/9376	5.93417721518987	SYT1	2.03616235155032
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/20	80/9376	5.86	PLCG2	2.01831400931884
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/20	86/9376	5.45116279069767	PLCG2	1.91721304771969
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/20	86/9376	5.45116279069767	CDH2	1.91721304771969
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/20	91/9376	5.15164835164835	PLCG2	1.83994920131691
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/20	93/9376	5.04086021505376	HLA-DRB1	1.81061725869943
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/20	95/9376	4.93473684210526	HLA-DRB1	1.78211463835577
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/20	98/9376	4.78367346938775	PLCG2	1.74082467142843
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/20	98/9376	4.78367346938775	PLCG2	1.74082467142843
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/20	99/9376	4.73535353535354	PLCG2	1.72743239862243
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/20	100/9376	4.688	HLA-DRB1	1.71421808209803
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/20	101/9376	4.64158415841584	PLCG2	1.70117741494846
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/20	105/9376	4.46476190476191	PLCG2	1.65067009812867
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/20	105/9376	4.46476190476191	PLCG2	1.65067009812867
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/20	109/9376	4.30091743119266	HLA-DRB1	1.60263217667027
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/20	110/9376	4.26181818181818	PLCG2	1.59098275888582
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/20	110/9376	4.26181818181818	ID3	1.59098275888582
NA	NA	hsa04519	Cadherin signaling	2/20	404/9376	2.32079207920792	CDH2/CDH12	1.25468884069957
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/20	116/9376	4.04137931034483	PLCG2	1.52387596034699
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/20	120/9376	3.90666666666667	PLCG2	1.48159570283513
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/20	122/9376	3.84262295081967	PLCG2	1.46113369255766
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/20	122/9376	3.84262295081967	PLCG2	1.46113369255766
Organismal Systems	Immune system	hsa04611	Platelet activation	1/20	126/9376	3.72063492063492	PLCG2	1.4214782003701
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/20	133/9376	3.52481203007519	TNFSF10	1.35582589498293
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/20	136/9376	3.44705882352941	HSPA1B	1.32902578600563
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/20	137/9376	3.42189781021898	TNFSF10	1.32025902228434
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/20	139/9376	3.3726618705036	HSPA1B	1.30296667680754
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/20	142/9376	3.30140845070423	PLCG2	1.27761049307071
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/20	143/9376	3.27832167832168	HLA-DRB1	1.26930845494202
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/20	144/9376	3.25555555555556	ID3	1.26107932631419
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/20	149/9376	3.14630872483221	PLCG2	1.22098574717137
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/20	155/9376	3.02451612903226	HLA-DRB1	1.17504259137042
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/20	168/9376	2.79047619047619	TNFSF10	1.08266990588691
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/20	170/9376	2.75764705882353	RAB13	1.06924241130768
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/20	170/9376	2.75764705882353	PLCG2	1.06924241130768
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/20	174/9376	2.69425287356322	HSPA1B	1.04295908148857
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/20	180/9376	2.60444444444444	HLA-DRB1	1.00488643685928
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/20	181/9376	2.59005524861878	HLA-DRB1	0.998691066047727
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/20	183/9376	2.56174863387978	RMRP	0.986423883616965
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/20	184/9376	2.54782608695652	PLCG2	0.980350997539969
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/20	194/9376	2.41649484536082	KIF9	0.921727932300927
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/20	195/9376	2.40410256410256	PLCG2	0.916065808859919
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/20	196/9376	2.39183673469388	PLCG2	0.910438299969023
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/20	200/9376	2.344	TNFSF10	0.888266111576046
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/20	201/9376	2.33233830845771	PAX8	0.882805513729981
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	1/20	204/9376	2.29803921568627	PLCG2	0.866615402368112
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/20	214/9376	2.19065420560748	PLCG2	0.814615975339017
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/20	224/9376	2.09285714285714	HLA-DRB1	0.765393779034458
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/20	233/9376	2.01201716738197	CSRP1	0.723230961206668
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/20	238/9376	1.96974789915966	PLCG2	0.700611527276542
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/20	238/9376	1.96974789915966	PLCG2	0.700611527276542
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/20	243/9376	1.92921810699589	HSPA1B	0.678530855320068
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/20	248/9376	1.89032258064516	TNFSF10	0.656963047674288
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/20	250/9376	1.8752	HSPA1B	0.648474063399921
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/20	253/9376	1.85296442687747	PLCG2	0.635883962384914
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/20	254/9376	1.84566929133858	PLCG2	0.631724782021106
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/20	300/9376	1.56266666666667	HSPA1B	0.457952148413946
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/20	323/9376	1.45139318885449	PLCG2	0.381694174844688