ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 25/1466 68/18639 0.367647058823529 4.67433392183613 1.95421584785888e-11 2.25516508842914e-08 GO:0022853 active monoatomic ion transmembrane transporter activity 32/1466 118/18639 0.271186440677966 3.44791546234421 3.13189841535981e-10 1.80710538566261e-07 GO:0009055 electron transfer activity 31/1466 116/18639 0.267241379310345 3.39775720938985 8.78152913701784e-10 2.54537993250265e-07 GO:0008017 microtubule binding 53/1466 276/18639 0.192028985507246 2.44149267453586 9.61983052844829e-10 2.54537993250265e-07 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 21/1466 58/18639 0.362068965517241 4.60341299336689 1.10285092396128e-09 2.54537993250265e-07 GO:0003954 NADH dehydrogenase activity 17/1466 44/18639 0.386363636363636 4.91230001240233 1.36114032656929e-08 2.61792656143494e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity 16/1466 41/18639 0.390243902439024 4.9616344458124 3.07514677620903e-08 5.06959911392174e-06 GO:0016651 oxidoreductase activity, acting on NAD(P)H 24/1466 88/18639 0.272727272727273 3.46750589110753 4.49061502593646e-08 6.47771217491335e-06 GO:0015399 primary active transmembrane transporter activity 35/1466 166/18639 0.210843373493976 2.68070234553494 6.07688365929443e-08 7.79191526980642e-06 GO:0015631 tubulin binding 60/1466 385/18639 0.155844155844156 1.98143193777573 2.46950719018927e-07 2.84981129747842e-05 GO:0015078 proton transmembrane transporter activity 35/1466 185/18639 0.189189189189189 2.40538696950702 9.49549822312775e-07 9.96164086317221e-05 GO:0003697 single-stranded DNA binding 26/1466 121/18639 0.214876033057851 2.73197433844836 2.02424841517604e-06 0.000194665222592762 GO:0016887 ATP hydrolysis activity 59/1466 417/18639 0.141486810551559 1.79888994670566 7.45783232731769e-06 0.000662026038901894 GO:0016675 oxidoreductase activity, acting on a heme group of donors 8/1466 16/18639 0.5 6.35709413369714 1.04217600781125e-05 0.000859050795010132 GO:0003777 microtubule motor activity 16/1466 68/18639 0.235294117647059 2.99157370997512 5.74269853082103e-05 0.00441804940304498 GO:0004129 cytochrome-c oxidase activity 7/1466 15/18639 0.466666666666667 5.93328785811733 6.71757023563734e-05 0.00484504753245343 GO:0003688 DNA replication origin binding 7/1466 16/18639 0.4375 5.56245736698499 0.000111317657461687 0.00755650451239925 GO:0042277 peptide binding 37/1466 249/18639 0.14859437751004 1.88925689113891 0.000131531233510937 0.00843261352620117 GO:0000217 DNA secondary structure binding 11/1466 39/18639 0.282051282051282 3.58605310105992 0.000146390375238308 0.00889128910657931 GO:0003678 DNA helicase activity 16/1466 74/18639 0.216216216216216 2.7490136794366 0.000167762229622992 0.00967988064924666 GO:0140097 catalytic activity, acting on DNA 45/1466 336/18639 0.133928571428571 1.70279307152602 0.00030852543049339 0.0169542069899701 GO:0004601 peroxidase activity 13/1466 57/18639 0.228070175438596 2.89972714870396 0.000387244190006223 0.0203127179666901 GO:0017116 single-stranded DNA helicase activity 13/1466 58/18639 0.224137931034483 2.84973185303665 0.000463667643441883 0.0232640200231275 GO:0032395 MHC class II receptor activity 5/1466 10/18639 0.5 6.35709413369714 0.000538393524980788 0.0255030526366854 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 13/1466 59/18639 0.220338983050847 2.80143131315467 0.000552492474798211 0.0255030526366854 GO:0050840 extracellular matrix binding 14/1466 67/18639 0.208955223880597 2.65669605587343 0.000607740915532357 0.0269743467893977 GO:0023026 MHC class II protein complex binding 8/1466 27/18639 0.296296296296296 3.76716689404275 0.000821790453787744 0.0350004173108502 GO:0061749 forked DNA-dependent helicase activity 11/1466 47/18639 0.234042553191489 2.97566108385823 0.000849230229379381 0.0350004173108502 GO:0016209 antioxidant activity 16/1466 86/18639 0.186046511627907 2.36543037532917 0.000985655461779463 0.037807837518067 GO:0009378 four-way junction helicase activity 11/1466 48/18639 0.229166666666667 2.91366814461119 0.00102453040477395 0.037807837518067 GO:0036121 double-stranded DNA helicase activity 11/1466 48/18639 0.229166666666667 2.91366814461119 0.00102453040477395 0.037807837518067 GO:0008094 ATP-dependent activity, acting on DNA 30/1466 210/18639 0.142857142857143 1.81631260962775 0.00104839757415784 0.037807837518067 GO:0030695 GTPase regulator activity 57/1466 489/18639 0.116564417177914 1.48202194527909 0.00179261719171766 0.059382626499815 GO:0023023 MHC protein complex binding 9/1466 37/18639 0.243243243243243 3.09264038936617 0.00185683422865124 0.059382626499815 GO:0060589 nucleoside-triphosphatase regulator activity 57/1466 490/18639 0.116326530612245 1.47899741069688 0.00187766151378406 0.059382626499815 GO:0001540 amyloid-beta binding 15/1466 83/18639 0.180722891566265 2.29774486760137 0.00189536662623388 0.059382626499815 GO:0000400 four-way junction DNA binding 6/1466 18/18639 0.333333333333333 4.23806275579809 0.00190394902989008 0.059382626499815 GO:0004386 helicase activity 23/1466 155/18639 0.148387096774194 1.88662148483915 0.00233301388030818 0.0708499478388327 GO:0005096 GTPase activator activity 35/1466 271/18639 0.129151291512915 1.64205383527232 0.00253709937924995 0.0749904171287403 GO:0008574 plus-end-directed microtubule motor activity 6/1466 19/18639 0.315789473684211 4.0150068212824 0.00259932121763398 0.0749904171287403 GO:1990518 single-stranded 3'-5' DNA helicase activity 10/1466 47/18639 0.212765957446809 2.70514643987112 0.00308767862287924 0.086906856848845 GO:0042813 Wnt receptor activity 5/1466 14/18639 0.357142857142857 4.54078152406938 0.0032763193553935 0.0884880374460255 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 9/1466 40/18639 0.225 2.86069236016371 0.00329721456687963 0.0884880374460255 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 10/1466 48/18639 0.208333333333333 2.64878922237381 0.00363061236448591 0.0931050370803719 GO:0043138 3'-5' DNA helicase activity 10/1466 48/18639 0.208333333333333 2.64878922237381 0.00363061236448591 0.0931050370803719 GO:0005178 integrin binding 23/1466 161/18639 0.142857142857143 1.81631260962775 0.00380465297107501 0.0939517198522698 GO:0003779 actin binding 51/1466 443/18639 0.115124153498871 1.46371016170905 0.00389489019396432 0.0939517198522698 GO:0015616 DNA translocase activity 22/1466 152/18639 0.144736842105263 1.84021145975443 0.00390787049645489 0.0939517198522698 GO:0008376 acetylgalactosaminyltransferase activity 8/1466 34/18639 0.235294117647059 2.99157370997512 0.00410498796999912 0.0966766554567139 GO:0003774 cytoskeletal motor activity 22/1466 153/18639 0.143790849673203 1.82818393387369 0.00423413060517365 0.0977237343674077 GO:0070182 DNA polymerase binding 6/1466 21/18639 0.285714285714286 3.63262521925551 0.00453774091664649 0.102677510153138 GO:0003684 damaged DNA binding 13/1466 74/18639 0.175675675675676 2.23357361454224 0.00476129017162624 0.104765155705657 GO:0019838 growth factor binding 20/1466 136/18639 0.147058823529412 1.86973356873445 0.00481157127590973 0.104765155705657 GO:0098631 cell adhesion mediator activity 13/1466 76/18639 0.171052631578947 2.17479536152797 0.00600631500907391 0.128357176305024 GO:0022804 active transmembrane transporter activity 51/1466 457/18639 0.111597374179431 1.41887002546413 0.00712824916569326 0.139695112113294 GO:0003689 DNA clamp loader activity 22/1466 160/18639 0.1375 1.74820088676671 0.0072106638786203 0.139695112113294 GO:0004602 glutathione peroxidase activity 6/1466 23/18639 0.260869565217391 3.3167447654072 0.00737208764197158 0.139695112113294 GO:0001968 fibronectin binding 7/1466 30/18639 0.233333333333333 2.96664392905866 0.00748050969392112 0.139695112113294 GO:0000510 H3-H4 histone complex chaperone activity 21/1466 151/18639 0.139072847682119 1.76819836831311 0.00750528331977836 0.139695112113294 GO:0140584 chromatin extrusion motor activity 21/1466 151/18639 0.139072847682119 1.76819836831311 0.00750528331977836 0.139695112113294 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 21/1466 151/18639 0.139072847682119 1.76819836831311 0.00750528331977836 0.139695112113294 GO:0140849 ATP-dependent H2AZ histone chaperone activity 21/1466 151/18639 0.139072847682119 1.76819836831311 0.00750528331977836 0.139695112113294 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 4/1466 11/18639 0.363636363636364 4.62334118814337 0.00802382700115299 0.143486013264192 GO:0019206 nucleoside kinase activity 4/1466 11/18639 0.363636363636364 4.62334118814337 0.00802382700115299 0.143486013264192 GO:0140674 ATP-dependent histone chaperone activity 21/1466 152/18639 0.138157894736842 1.75656548431105 0.00808196781817373 0.143486013264192 GO:0061775 cohesin loader activity 21/1466 153/18639 0.137254901960784 1.74508466415215 0.00869412373842373 0.152015436274863 GO:0140299 molecular sensor activity 12/1466 71/18639 0.169014084507042 2.14887689026382 0.0089380653444853 0.153948170261732 GO:0140612 DNA damage sensor activity 6/1466 24/18639 0.25 3.17854706684857 0.00918751220560718 0.155917486548098 GO:0140713 histone chaperone activity 22/1466 164/18639 0.134146341463415 1.70556184074801 0.00956704885617601 0.160005425797494 GO:0031690 adrenergic receptor binding 5/1466 18/18639 0.277777777777778 3.53171896316507 0.0107667317184452 0.177497262901225 GO:0016801 hydrolase activity, acting on ether bonds 4/1466 12/18639 0.333333333333333 4.23806275579809 0.011295492789292 0.178561625737575 GO:0016803 ether hydrolase activity 4/1466 12/18639 0.333333333333333 4.23806275579809 0.011295492789292 0.178561625737575 GO:0031543 peptidyl-proline dioxygenase activity 4/1466 12/18639 0.333333333333333 4.23806275579809 0.011295492789292 0.178561625737575 GO:0140658 ATP-dependent chromatin remodeler activity 21/1466 158/18639 0.132911392405063 1.68986046591949 0.0123416265388487 0.192462662511234 GO:0140597 protein carrier chaperone 24/1466 188/18639 0.127659574468085 1.62308786392267 0.0126663576026564 0.194682869632508 GO:0030246 carbohydrate binding 33/1466 280/18639 0.117857142857143 1.4984579029429 0.0128214021595066 0.194682869632508 GO:0005200 structural constituent of cytoskeleton 16/1466 112/18639 0.142857142857143 1.81631260962775 0.014228373595485 0.213240819859606 GO:0140666 annealing activity 4/1466 13/18639 0.307692307692308 3.91205792842901 0.0153153308919319 0.226588357042173 GO:0031418 L-ascorbic acid binding 5/1466 20/18639 0.25 3.17854706684857 0.0170885376257665 0.249622435697905 GO:0008194 UDP-glycosyltransferase activity 19/1466 145/18639 0.131034482758621 1.66599708331373 0.0191866161643479 0.276766938170718 GO:0016835 carbon-oxygen lyase activity 12/1466 79/18639 0.151898734177215 1.93126910390799 0.0201100863626005 0.283306092372629 GO:0042043 neurexin family protein binding 4/1466 14/18639 0.285714285714286 3.63262521925551 0.0201309355065473 0.283306092372629 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 5/1466 21/18639 0.238095238095238 3.02718768271292 0.0210106615973665 0.292124138353747 GO:0140104 molecular carrier activity 29/1466 249/18639 0.116465863453815 1.48076891467644 0.0216374937942649 0.297257950459306 GO:0050661 NADP binding 9/1466 54/18639 0.166666666666667 2.11903137789905 0.0239254934712704 0.324823758421719 GO:0005501 retinoid binding 7/1466 38/18639 0.184210526315789 2.34208731241473 0.026833125566808 0.351431351529619 GO:0019840 isoprenoid binding 7/1466 38/18639 0.184210526315789 2.34208731241473 0.026833125566808 0.351431351529619 GO:0001965 G-protein alpha-subunit binding 6/1466 30/18639 0.2 2.54283765347885 0.0271034577869463 0.351431351529619 GO:0098918 structural constituent of synapse 6/1466 30/18639 0.2 2.54283765347885 0.0271034577869463 0.351431351529619 GO:0003712 transcription coregulator activity 51/1466 495/18639 0.103030303030303 1.30994666997396 0.0285813141187404 0.363458531486382 GO:0019887 protein kinase regulator activity 29/1466 255/18639 0.113725490196078 1.44592729315464 0.0286609413910405 0.363458531486382 GO:0099186 structural constituent of postsynapse 5/1466 23/18639 0.217391304347826 2.76395397117267 0.0305041503912124 0.382628147298468 GO:0003714 transcription corepressor activity 24/1466 204/18639 0.117647058823529 1.49578685498756 0.0308756080822225 0.383123136848223 GO:0017147 Wnt-protein binding 6/1466 31/18639 0.193548387096774 2.46081063239889 0.0314434730936984 0.386018807980085 GO:0005159 insulin-like growth factor receptor binding 4/1466 16/18639 0.25 3.17854706684857 0.0322843949718474 0.392170439973809 GO:0051087 protein-folding chaperone binding 17/1466 134/18639 0.126865671641791 1.61299403392315 0.0338721257962305 0.407171178842188 GO:0070840 dynein complex binding 5/1466 24/18639 0.208333333333333 2.64878922237381 0.0361137920190032 0.429333101211902 GO:0004090 carbonyl reductase (NADPH) activity 3/1466 10/18639 0.3 3.81425648021828 0.0383200254981161 0.429333101211902 GO:0005345 purine nucleobase transmembrane transporter activity 3/1466 10/18639 0.3 3.81425648021828 0.0383200254981161 0.429333101211902 GO:0015643 toxic substance binding 3/1466 10/18639 0.3 3.81425648021828 0.0383200254981161 0.429333101211902 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 3/1466 10/18639 0.3 3.81425648021828 0.0383200254981161 0.429333101211902 GO:0035374 chondroitin sulfate binding 3/1466 10/18639 0.3 3.81425648021828 0.0383200254981161 0.429333101211902 GO:0051880 G-quadruplex DNA binding 3/1466 10/18639 0.3 3.81425648021828 0.0383200254981161 0.429333101211902 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 7/1466 41/18639 0.170731707317073 2.17071507004292 0.0390112961077141 0.42953978160529 GO:0000287 magnesium ion binding 26/1466 230/18639 0.11304347826087 1.43725606500979 0.0390829090715386 0.42953978160529 GO:0070402 NADPH binding 4/1466 17/18639 0.235294117647059 2.99157370997512 0.0396627172283263 0.431799770580081 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 6/1466 33/18639 0.181818181818182 2.31167059407169 0.0414203452353383 0.446720358893275 GO:0004520 DNA endonuclease activity 7/1466 42/18639 0.166666666666667 2.11903137789905 0.0437587070460896 0.462110181827199 GO:0005048 signal sequence binding 8/1466 51/18639 0.156862745098039 1.99438247331675 0.0443275174645753 0.462110181827199 GO:0016853 isomerase activity 21/1466 180/18639 0.116666666666667 1.48332196452933 0.0446212242635027 0.462110181827199 GO:0019207 kinase regulator activity 31/1466 287/18639 0.10801393728223 1.37330953410879 0.0446229740580749 0.462110181827199 GO:0015035 protein-disulfide reductase activity 6/1466 34/18639 0.176470588235294 2.24368028248134 0.0470769664793839 0.462110181827199 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 6/1466 34/18639 0.176470588235294 2.24368028248134 0.0470769664793839 0.462110181827199 GO:0030332 cyclin binding 6/1466 34/18639 0.176470588235294 2.24368028248134 0.0470769664793839 0.462110181827199 GO:0008409 5'-3' exonuclease activity 4/1466 18/18639 0.222222222222222 2.82537517053206 0.0479187130882923 0.462110181827199 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 4/1466 18/18639 0.222222222222222 2.82537517053206 0.0479187130882923 0.462110181827199 GO:0004712 protein serine/threonine/tyrosine kinase activity 7/1466 43/18639 0.162790697674419 2.06975157841302 0.0488628268918815 0.462110181827199 GO:0008432 JUN kinase binding 3/1466 11/18639 0.272727272727273 3.46750589110753 0.0496810999344772 0.462110181827199 GO:0010854 adenylate cyclase regulator activity 3/1466 11/18639 0.272727272727273 3.46750589110753 0.0496810999344772 0.462110181827199 GO:0015205 nucleobase transmembrane transporter activity 3/1466 11/18639 0.272727272727273 3.46750589110753 0.0496810999344772 0.462110181827199 GO:0042608 T cell receptor binding 3/1466 11/18639 0.272727272727273 3.46750589110753 0.0496810999344772 0.462110181827199 GO:0048407 platelet-derived growth factor binding 3/1466 11/18639 0.272727272727273 3.46750589110753 0.0496810999344772 0.462110181827199 GO:0050786 RAGE receptor binding 3/1466 11/18639 0.272727272727273 3.46750589110753 0.0496810999344772 0.462110181827199 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 3/1466 11/18639 0.272727272727273 3.46750589110753 0.0496810999344772 0.462110181827199 GO:0045296 cadherin binding 35/1466 334/18639 0.104790419161677 1.33232511784072 0.050055262329636 0.462110181827199 GO:0008201 heparin binding 20/1466 172/18639 0.116279069767442 1.47839398458073 0.050515353814979 0.462656494464173 GO:0042393 histone binding 27/1466 247/18639 0.109311740890688 1.38981005352083 0.0511900449866365 0.465144188303768 GO:0019205 nucleobase-containing compound kinase activity 7/1466 44/18639 0.159090909090909 2.02271176981272 0.0543292450946998 0.489812100306903 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 4/1466 19/18639 0.210526315789474 2.67667121418827 0.0570480595011267 0.49498842604737 GO:0005229 intracellularly calcium-gated chloride channel activity 4/1466 19/18639 0.210526315789474 2.67667121418827 0.0570480595011267 0.49498842604737 GO:0008301 DNA binding, bending 4/1466 19/18639 0.210526315789474 2.67667121418827 0.0570480595011267 0.49498842604737 GO:0042577 lipid phosphatase activity 4/1466 19/18639 0.210526315789474 2.67667121418827 0.0570480595011267 0.49498842604737 GO:0141147 intracellularly calcium-gated channel activity 4/1466 19/18639 0.210526315789474 2.67667121418827 0.0570480595011267 0.49498842604737 GO:0051287 NAD binding 8/1466 54/18639 0.148148148148148 1.88358344702137 0.059022537792542 0.508298571735772 GO:0042605 peptide antigen binding 7/1466 45/18639 0.155555555555556 1.97776261937244 0.0601621541424541 0.514275006521422 GO:0005247 voltage-gated chloride channel activity 3/1466 12/18639 0.25 3.17854706684857 0.0624763023162056 0.517163887047175 GO:0010853 cyclase activator activity 3/1466 12/18639 0.25 3.17854706684857 0.0624763023162056 0.517163887047175 GO:0016840 carbon-nitrogen lyase activity 3/1466 12/18639 0.25 3.17854706684857 0.0624763023162056 0.517163887047175 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 3/1466 12/18639 0.25 3.17854706684857 0.0624763023162056 0.517163887047175 GO:0042578 phosphoric ester hydrolase activity 37/1466 363/18639 0.101928374655647 1.2959365451614 0.0627408528480109 0.517163887047175 GO:0140297 DNA-binding transcription factor binding 48/1466 488/18639 0.0983606557377049 1.25057589515353 0.0635516637815719 0.517947709944644 GO:0051015 actin filament binding 23/1466 209/18639 0.110047846889952 1.39916904378023 0.0637336003571399 0.517947709944644 GO:0004860 protein kinase inhibitor activity 11/1466 84/18639 0.130952380952381 1.66495322549211 0.0643872505188282 0.519600609082012 GO:0001972 retinoic acid binding 4/1466 20/18639 0.2 2.54283765347885 0.0670379399699667 0.529875224146175 GO:0010851 cyclase regulator activity 4/1466 20/18639 0.2 2.54283765347885 0.0670379399699667 0.529875224146175 GO:0140664 ATP-dependent DNA damage sensor activity 4/1466 20/18639 0.2 2.54283765347885 0.0670379399699667 0.529875224146175 GO:0016829 lyase activity 22/1466 200/18639 0.11 1.39856070941337 0.0688200889819455 0.540261106701804 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 5/1466 29/18639 0.172413793103448 2.19210142541281 0.0731697051308599 0.562918931473416 GO:0043236 laminin binding 5/1466 29/18639 0.172413793103448 2.19210142541281 0.0731697051308599 0.562918931473416 GO:0097472 cyclin-dependent protein kinase activity 5/1466 29/18639 0.172413793103448 2.19210142541281 0.0731697051308599 0.562918931473416 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 28/1466 268/18639 0.104477611940299 1.32834802793671 0.075270864230317 0.563215166751495 GO:0005172 vascular endothelial growth factor receptor binding 3/1466 13/18639 0.230769230769231 2.93404344632175 0.0766245937434876 0.563215166751495 GO:0019104 DNA N-glycosylase activity 3/1466 13/18639 0.230769230769231 2.93404344632175 0.0766245937434876 0.563215166751495 GO:0019855 calcium channel inhibitor activity 3/1466 13/18639 0.230769230769231 2.93404344632175 0.0766245937434876 0.563215166751495 GO:0030955 potassium ion binding 3/1466 13/18639 0.230769230769231 2.93404344632175 0.0766245937434876 0.563215166751495 GO:0045159 myosin II binding 3/1466 13/18639 0.230769230769231 2.93404344632175 0.0766245937434876 0.563215166751495 GO:0140852 histone ubiquitin ligase activity 3/1466 13/18639 0.230769230769231 2.93404344632175 0.0766245937434876 0.563215166751495 GO:0061891 calcium ion sensor activity 4/1466 21/18639 0.19047619047619 2.42175014617034 0.0778678878223432 0.568731281942937 GO:0022839 monoatomic ion-gated channel activity 5/1466 30/18639 0.166666666666667 2.11903137789905 0.0823829545996427 0.597924085584828 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 11/1466 89/18639 0.123595505617978 1.57141652743075 0.0892738343742266 0.628431219901086 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 11/1466 89/18639 0.123595505617978 1.57141652743075 0.0892738343742266 0.628431219901086 GO:0031683 G-protein beta/gamma-subunit complex binding 4/1466 22/18639 0.181818181818182 2.31167059407169 0.0895106537611085 0.628431219901086 GO:0140784 metal ion sensor activity 4/1466 22/18639 0.181818181818182 2.31167059407169 0.0895106537611085 0.628431219901086 GO:0070888 E-box binding 8/1466 59/18639 0.135593220338983 1.7239577311721 0.0896363510700078 0.628431219901086 GO:0015036 disulfide oxidoreductase activity 6/1466 40/18639 0.15 1.90712824010914 0.0906356229055219 0.628431219901086 GO:0071949 FAD binding 6/1466 40/18639 0.15 1.90712824010914 0.0906356229055219 0.628431219901086 GO:0005161 platelet-derived growth factor receptor binding 3/1466 14/18639 0.214285714285714 2.72446891444163 0.092031955080835 0.628431219901086 GO:0008195 phosphatidate phosphatase activity 3/1466 14/18639 0.214285714285714 2.72446891444163 0.092031955080835 0.628431219901086 GO:0043176 amine binding 3/1466 14/18639 0.214285714285714 2.72446891444163 0.092031955080835 0.628431219901086 GO:0019210 kinase inhibitor activity 11/1466 90/18639 0.122222222222222 1.55395634379263 0.0948672651700128 0.638754075797427 GO:0140793 histone H2AXY142 phosphatase activity 11/1466 90/18639 0.122222222222222 1.55395634379263 0.0948672651700128 0.638754075797427 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 15/1466 132/18639 0.113636363636364 1.4447941212948 0.0952042469992698 0.638754075797427 GO:0097110 scaffold protein binding 9/1466 70/18639 0.128571428571429 1.63468134866498 0.096964981467053 0.646806870595255 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 14/1466 122/18639 0.114754098360656 1.45900521101246 0.0982232116671696 0.651434403815596 GO:0061650 ubiquitin-like protein conjugating enzyme activity 6/1466 41/18639 0.146341463414634 1.86061291717965 0.0994855074994318 0.656035860881968 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 4/1466 23/18639 0.173913043478261 2.21116317693813 0.101933075523192 0.663474230318825 GO:0042910 xenobiotic transmembrane transporter activity 5/1466 32/18639 0.15625 1.98659191678035 0.102543251013198 0.663474230318825 GO:0043425 bHLH transcription factor binding 5/1466 32/18639 0.15625 1.98659191678035 0.102543251013198 0.663474230318825 GO:0030544 Hsp70 protein binding 7/1466 51/18639 0.137254901960784 1.74508466415215 0.102913247163839 0.663474230318825 GO:0001217 DNA-binding transcription repressor activity 28/1466 278/18639 0.100719424460432 1.28056572477352 0.105662482317059 0.674862349148048 GO:0004857 enzyme inhibitor activity 40/1466 416/18639 0.0961538461538462 1.22251810263406 0.107981485586516 0.674862349148048 GO:0004559 alpha-mannosidase activity 3/1466 15/18639 0.2 2.54283765347885 0.108595247670552 0.674862349148048 GO:0005523 tropomyosin binding 3/1466 15/18639 0.2 2.54283765347885 0.108595247670552 0.674862349148048 GO:0055105 ubiquitin-protein transferase inhibitor activity 3/1466 15/18639 0.2 2.54283765347885 0.108595247670552 0.674862349148048 GO:0008307 structural constituent of muscle 6/1466 42/18639 0.142857142857143 1.81631260962775 0.108773307574989 0.674862349148048 GO:0031492 nucleosomal DNA binding 6/1466 42/18639 0.142857142857143 1.81631260962775 0.108773307574989 0.674862349148048 GO:0005518 collagen binding 9/1466 72/18639 0.125 1.58927353342428 0.110749209498898 0.683446993378225 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 4/1466 24/18639 0.166666666666667 2.11903137789905 0.11509693222403 0.699062419929107 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 4/1466 24/18639 0.166666666666667 2.11903137789905 0.11509693222403 0.699062419929107 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/1466 24/18639 0.166666666666667 2.11903137789905 0.11509693222403 0.699062419929107 GO:0005507 copper ion binding 8/1466 63/18639 0.126984126984127 1.61450009744689 0.119642342754117 0.717868607904915 GO:0004864 protein phosphatase inhibitor activity 7/1466 53/18639 0.132075471698113 1.67923241267471 0.120059481218066 0.717868607904915 GO:0016860 intramolecular oxidoreductase activity 7/1466 53/18639 0.132075471698113 1.67923241267471 0.120059481218066 0.717868607904915 GO:0048029 monosaccharide binding 9/1466 74/18639 0.121621621621622 1.54632019468309 0.12556420505194 0.734183269185292 GO:0015923 mannosidase activity 3/1466 16/18639 0.1875 2.38391030013643 0.126205444447176 0.734183269185292 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 3/1466 16/18639 0.1875 2.38391030013643 0.126205444447176 0.734183269185292 GO:0004536 DNA nuclease activity 8/1466 64/18639 0.125 1.58927353342428 0.127885207251239 0.734183269185292 GO:0016791 phosphatase activity 27/1466 273/18639 0.0989010989010989 1.25744719128075 0.128820205393055 0.734183269185292 GO:0015662 P-type ion transporter activity 4/1466 25/18639 0.16 2.03427012278308 0.128959769965603 0.734183269185292 GO:0042974 nuclear retinoic acid receptor binding 4/1466 25/18639 0.16 2.03427012278308 0.128959769965603 0.734183269185292 GO:0047617 fatty acyl-CoA hydrolase activity 4/1466 25/18639 0.16 2.03427012278308 0.128959769965603 0.734183269185292 GO:0140358 P-type transmembrane transporter activity 4/1466 25/18639 0.16 2.03427012278308 0.128959769965603 0.734183269185292 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/1466 54/18639 0.12962962962963 1.6481355161437 0.129150089813357 0.734183269185292 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 14/1466 128/18639 0.109375 1.39061434174625 0.130713845973346 0.739284912330762 GO:0019842 vitamin binding 16/1466 150/18639 0.106666666666667 1.35618008185539 0.131328775587354 0.739284912330762 GO:0019888 protein phosphatase regulator activity 12/1466 107/18639 0.11214953271028 1.4258902729788 0.134696142744017 0.754559945274737 GO:0038024 cargo receptor activity 8/1466 65/18639 0.123076923076923 1.5648231713716 0.136413892894765 0.755845533975514 GO:0061631 ubiquitin conjugating enzyme activity 5/1466 35/18639 0.142857142857143 1.81631260962775 0.136855509716731 0.755845533975514 GO:0005539 glycosaminoglycan binding 24/1466 242/18639 0.0991735537190083 1.26091123313001 0.142177067118931 0.755845533975514 GO:0004112 cyclic-nucleotide phosphodiesterase activity 4/1466 26/18639 0.153846153846154 1.9560289642145 0.143475688637734 0.755845533975514 GO:0005227 calcium-activated cation channel activity 4/1466 26/18639 0.153846153846154 1.9560289642145 0.143475688637734 0.755845533975514 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/1466 26/18639 0.153846153846154 1.9560289642145 0.143475688637734 0.755845533975514 GO:0016289 acyl-CoA hydrolase activity 4/1466 26/18639 0.153846153846154 1.9560289642145 0.143475688637734 0.755845533975514 GO:0030247 polysaccharide binding 4/1466 26/18639 0.153846153846154 1.9560289642145 0.143475688637734 0.755845533975514 GO:0034237 protein kinase A regulatory subunit binding 4/1466 26/18639 0.153846153846154 1.9560289642145 0.143475688637734 0.755845533975514 GO:0004550 nucleoside diphosphate kinase activity 3/1466 17/18639 0.176470588235294 2.24368028248134 0.144750314565501 0.755845533975514 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/1466 17/18639 0.176470588235294 2.24368028248134 0.144750314565501 0.755845533975514 GO:0005092 GDP-dissociation inhibitor activity 3/1466 17/18639 0.176470588235294 2.24368028248134 0.144750314565501 0.755845533975514 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/1466 17/18639 0.176470588235294 2.24368028248134 0.144750314565501 0.755845533975514 GO:0019198 transmembrane receptor protein phosphatase activity 3/1466 17/18639 0.176470588235294 2.24368028248134 0.144750314565501 0.755845533975514 GO:0048038 quinone binding 3/1466 17/18639 0.176470588235294 2.24368028248134 0.144750314565501 0.755845533975514 GO:0004725 protein tyrosine phosphatase activity 11/1466 98/18639 0.112244897959184 1.42710276470752 0.146905059510337 0.763641615652835 GO:0019212 phosphatase inhibitor activity 7/1466 56/18639 0.125 1.58927353342428 0.148321748374951 0.764278166076202 GO:0004869 cysteine-type endopeptidase inhibitor activity 5/1466 36/18639 0.138888888888889 1.76585948158254 0.149290440465808 0.764278166076202 GO:0055106 ubiquitin-protein transferase regulator activity 5/1466 36/18639 0.138888888888889 1.76585948158254 0.149290440465808 0.764278166076202 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1466 46/18639 0.130434782608696 1.6583723827036 0.150068706177824 0.764278166076202 GO:0031406 carboxylic acid binding 19/1466 187/18639 0.101604278074866 1.29181592021653 0.150338946013256 0.764278166076202 GO:0016757 glycosyltransferase activity 26/1466 267/18639 0.0973782771535581 1.23808574888484 0.151482342261911 0.766713258641424 GO:0003713 transcription coactivator activity 25/1466 256/18639 0.09765625 1.24161994798772 0.153679790425499 0.770836542096967 GO:0005506 iron ion binding 16/1466 154/18639 0.103896103896104 1.32095462518382 0.154002760255671 0.770836542096967 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 8/1466 67/18639 0.119402985074627 1.51811203192767 0.154300902274176 0.770836542096967 GO:0004364 glutathione transferase activity 4/1466 27/18639 0.148148148148148 1.88358344702137 0.15859608263489 0.787250220825959 GO:0043177 organic acid binding 19/1466 189/18639 0.100529100529101 1.27814591047879 0.161078909392345 0.787250220825959 GO:0005504 fatty acid binding 6/1466 47/18639 0.127659574468085 1.62308786392267 0.161356250790732 0.787250220825959 GO:0008308 voltage-gated monoatomic anion channel activity 3/1466 18/18639 0.166666666666667 2.11903137789905 0.164116634860943 0.787250220825959 GO:0015280 ligand-gated sodium channel activity 3/1466 18/18639 0.166666666666667 2.11903137789905 0.164116634860943 0.787250220825959 GO:0035615 clathrin adaptor activity 3/1466 18/18639 0.166666666666667 2.11903137789905 0.164116634860943 0.787250220825959 GO:0033218 amide binding 24/1466 247/18639 0.097165991902834 1.23538671424074 0.165410149783477 0.787250220825959 GO:0008186 ATP-dependent activity, acting on RNA 9/1466 79/18639 0.113924050632911 1.44845182793099 0.166889364710755 0.787250220825959 GO:0033293 monocarboxylic acid binding 9/1466 79/18639 0.113924050632911 1.44845182793099 0.166889364710755 0.787250220825959 GO:0045499 chemorepellent activity 4/1466 28/18639 0.142857142857143 1.81631260962775 0.174270330522415 0.787250220825959 GO:0004879 nuclear receptor activity 7/1466 59/18639 0.11864406779661 1.50846301477559 0.179391707343921 0.787250220825959 GO:0140789 histone phosphatase activity 14/1466 136/18639 0.102941176470588 1.30881349811412 0.18228215713429 0.787250220825959 GO:0001094 TFIID-class transcription factor complex binding 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0004935 adrenergic receptor activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0005031 tumor necrosis factor receptor activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0005337 nucleoside transmembrane transporter activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0005528 FK506 binding 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0016783 sulfurtransferase activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0016868 intramolecular phosphotransferase activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0019911 structural constituent of myelin sheath 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0031419 cobalamin binding 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0031996 thioesterase binding 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0032356 oxidized DNA binding 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0051378 serotonin binding 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0141109 transporter activator activity 2/1466 10/18639 0.2 2.54283765347885 0.182886593582113 0.787250220825959 GO:0005520 insulin-like growth factor binding 3/1466 19/18639 0.157894736842105 2.0075034106412 0.184191992740909 0.787250220825959 GO:0016918 retinal binding 3/1466 19/18639 0.157894736842105 2.0075034106412 0.184191992740909 0.787250220825959 GO:0031420 alkali metal ion binding 3/1466 19/18639 0.157894736842105 2.0075034106412 0.184191992740909 0.787250220825959 GO:0097001 ceramide binding 3/1466 19/18639 0.157894736842105 2.0075034106412 0.184191992740909 0.787250220825959 GO:0140036 ubiquitin-modified protein reader activity 3/1466 19/18639 0.157894736842105 2.0075034106412 0.184191992740909 0.787250220825959 GO:0001618 virus receptor activity 9/1466 81/18639 0.111111111111111 1.41268758526603 0.185012454221055 0.787839011701465 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 7/1466 60/18639 0.116666666666667 1.48332196452933 0.190315311730216 0.802099200347314 GO:0098531 ligand-modulated transcription factor activity 7/1466 60/18639 0.116666666666667 1.48332196452933 0.190315311730216 0.802099200347314 GO:0035250 UDP-galactosyltransferase activity 4/1466 29/18639 0.137931034482759 1.75368114033024 0.190446430585064 0.802099200347314 GO:0140272 exogenous protein binding 9/1466 82/18639 0.109756097560976 1.39545968788474 0.194386982163979 0.806614927003864 GO:0004519 endonuclease activity 13/1466 127/18639 0.102362204724409 1.3014523423317 0.19874202255916 0.806614927003864 GO:0042826 histone deacetylase binding 13/1466 127/18639 0.102362204724409 1.3014523423317 0.19874202255916 0.806614927003864 GO:0016836 hydro-lyase activity 7/1466 61/18639 0.114754098360656 1.45900521101246 0.201499510562432 0.806614927003864 GO:0042562 hormone binding 10/1466 94/18639 0.106382978723404 1.35257321993556 0.203480620058786 0.806614927003864 GO:0030165 PDZ domain binding 9/1466 83/18639 0.108433734939759 1.37864692056082 0.203959361117334 0.806614927003864 GO:0016004 phospholipase activator activity 3/1466 20/18639 0.15 1.90712824010914 0.204866237347545 0.806614927003864 GO:0016505 peptidase activator activity involved in apoptotic process 3/1466 20/18639 0.15 1.90712824010914 0.204866237347545 0.806614927003864 GO:0008083 growth factor activity 16/1466 162/18639 0.0987654320987654 1.25572229801425 0.205125219879295 0.806614927003864 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/1466 30/18639 0.133333333333333 1.69522510231924 0.207071580736667 0.806614927003864 GO:0016769 transferase activity, transferring nitrogenous groups 4/1466 30/18639 0.133333333333333 1.69522510231924 0.207071580736667 0.806614927003864 GO:0033612 receptor serine/threonine kinase binding 4/1466 30/18639 0.133333333333333 1.69522510231924 0.207071580736667 0.806614927003864 GO:0016758 hexosyltransferase activity 19/1466 197/18639 0.0964467005076142 1.2262415080228 0.207953177290469 0.806614927003864 GO:0019208 phosphatase regulator activity 12/1466 117/18639 0.102564102564103 1.30401930947634 0.208812631604875 0.806614927003864 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0004523 RNA-DNA hybrid ribonuclease activity 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0005225 volume-sensitive anion channel activity 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0008199 ferric iron binding 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0015217 ADP transmembrane transporter activity 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0032794 GTPase activating protein binding 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0070697 activin receptor binding 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0140537 transcription regulator activator activity 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0180030 inositol phosphate kinase activity 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:1990948 ubiquitin ligase inhibitor activity 2/1466 11/18639 0.181818181818182 2.31167059407169 0.212487814392699 0.806614927003864 GO:0004721 phosphoprotein phosphatase activity 17/1466 175/18639 0.0971428571428571 1.23509257454687 0.215284181799585 0.812499925532917 GO:0046906 tetrapyrrole binding 15/1466 152/18639 0.0986842105263158 1.25468963165075 0.215446254084118 0.812499925532917 GO:0005080 protein kinase C binding 6/1466 52/18639 0.115384615384615 1.46702172316088 0.222683265316639 0.833359916265436 GO:0005164 tumor necrosis factor receptor binding 4/1466 31/18639 0.129032258064516 1.64054042159926 0.224092702514633 0.833359916265436 GO:0008327 methyl-CpG binding 4/1466 31/18639 0.129032258064516 1.64054042159926 0.224092702514633 0.833359916265436 GO:0019200 carbohydrate kinase activity 3/1466 21/18639 0.142857142857143 1.81631260962775 0.226032628935079 0.833359916265436 GO:0051010 microtubule plus-end binding 3/1466 21/18639 0.142857142857143 1.81631260962775 0.226032628935079 0.833359916265436 GO:0072542 protein phosphatase activator activity 3/1466 21/18639 0.142857142857143 1.81631260962775 0.226032628935079 0.833359916265436 GO:0140312 cargo adaptor activity 3/1466 21/18639 0.142857142857143 1.81631260962775 0.226032628935079 0.833359916265436 GO:0019894 kinesin binding 5/1466 42/18639 0.119047619047619 1.51359384135646 0.23243779608864 0.838884864377236 GO:0003924 GTPase activity 30/1466 331/18639 0.0906344410876133 1.15234334749797 0.233333074738328 0.838884864377236 GO:0038064 collagen receptor activity 6/1466 53/18639 0.113207547169811 1.4393420680069 0.235784173924967 0.838884864377236 GO:0051018 protein kinase A binding 6/1466 53/18639 0.113207547169811 1.4393420680069 0.235784173924967 0.838884864377236 GO:0042626 ATPase-coupled transmembrane transporter activity 10/1466 98/18639 0.102040816326531 1.29736614973411 0.240941613972723 0.838884864377236 GO:0008378 galactosyltransferase activity 4/1466 32/18639 0.125 1.58927353342428 0.241456909871981 0.838884864377236 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/1466 32/18639 0.125 1.58927353342428 0.241456909871981 0.838884864377236 GO:0071813 lipoprotein particle binding 4/1466 32/18639 0.125 1.58927353342428 0.241456909871981 0.838884864377236 GO:0071814 protein-lipid complex binding 4/1466 32/18639 0.125 1.58927353342428 0.241456909871981 0.838884864377236 GO:0019955 cytokine binding 14/1466 144/18639 0.0972222222222222 1.23610163710778 0.242187535687281 0.838884864377236 GO:0005527 macrolide binding 2/1466 12/18639 0.166666666666667 2.11903137789905 0.242490116807998 0.838884864377236 GO:0035259 nuclear glucocorticoid receptor binding 2/1466 12/18639 0.166666666666667 2.11903137789905 0.242490116807998 0.838884864377236 GO:0035497 cAMP response element binding 2/1466 12/18639 0.166666666666667 2.11903137789905 0.242490116807998 0.838884864377236 GO:0097371 MDM2/MDM4 family protein binding 2/1466 12/18639 0.166666666666667 2.11903137789905 0.242490116807998 0.838884864377236 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/1466 12/18639 0.166666666666667 2.11903137789905 0.242490116807998 0.838884864377236 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/1466 12/18639 0.166666666666667 2.11903137789905 0.242490116807998 0.838884864377236 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/1466 12/18639 0.166666666666667 2.11903137789905 0.242490116807998 0.838884864377236 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/1466 12/18639 0.166666666666667 2.11903137789905 0.242490116807998 0.838884864377236 GO:0008081 phosphoric diester hydrolase activity 9/1466 87/18639 0.103448275862069 1.31526085524768 0.244050747619546 0.838884864377236 GO:0008200 ion channel inhibitor activity 5/1466 43/18639 0.116279069767442 1.47839398458073 0.247431121803102 0.838884864377236 GO:0008093 cytoskeletal anchor activity 3/1466 22/18639 0.136363636363636 1.73375294555376 0.247588730278338 0.838884864377236 GO:0008649 rRNA methyltransferase activity 3/1466 22/18639 0.136363636363636 1.73375294555376 0.247588730278338 0.838884864377236 GO:0061133 endopeptidase activator activity 3/1466 22/18639 0.136363636363636 1.73375294555376 0.247588730278338 0.838884864377236 GO:0140035 ubiquitin-like protein reader activity 3/1466 22/18639 0.136363636363636 1.73375294555376 0.247588730278338 0.838884864377236 GO:0016247 channel regulator activity 16/1466 168/18639 0.0952380952380952 1.21087507308517 0.247954608836984 0.838884864377236 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/1466 54/18639 0.111111111111111 1.41268758526603 0.249113434438919 0.838884864377236 GO:0017069 snRNA binding 6/1466 54/18639 0.111111111111111 1.41268758526603 0.249113434438919 0.838884864377236 GO:1901681 sulfur compound binding 25/1466 275/18639 0.0909090909090909 1.15583529703584 0.252787564747625 0.838884864377236 GO:0004197 cysteine-type endopeptidase activity 9/1466 88/18639 0.102272727272727 1.30031470916532 0.254477244375735 0.838884864377236 GO:0003724 RNA helicase activity 8/1466 77/18639 0.103896103896104 1.32095462518382 0.257933150471295 0.838884864377236 GO:0030296 protein tyrosine kinase activator activity 4/1466 33/18639 0.121212121212121 1.54111372938112 0.259111924252063 0.838884864377236 GO:0140416 transcription regulator inhibitor activity 4/1466 33/18639 0.121212121212121 1.54111372938112 0.259111924252063 0.838884864377236 GO:0098632 cell-cell adhesion mediator activity 6/1466 55/18639 0.109090909090909 1.38700235644301 0.262648854884721 0.838884864377236 GO:0016248 channel inhibitor activity 5/1466 44/18639 0.113636363636364 1.4447941212948 0.262663453753512 0.838884864377236 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/1466 44/18639 0.113636363636364 1.4447941212948 0.262663453753512 0.838884864377236 GO:0141108 transporter regulator activity 16/1466 170/18639 0.0941176470588235 1.19662948399005 0.262963622954413 0.838884864377236 GO:0106310 protein serine kinase activity 32/1466 361/18639 0.0886426592797784 1.12701945860559 0.264365823264755 0.838884864377236 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 31/1466 349/18639 0.0888252148997135 1.12934050512671 0.264591783380159 0.838884864377236 GO:0005085 guanyl-nucleotide exchange factor activity 21/1466 230/18639 0.091304347826087 1.16086066789252 0.269011092429766 0.838884864377236 GO:0003887 DNA-directed DNA polymerase activity 3/1466 23/18639 0.130434782608696 1.6583723827036 0.26943707849161 0.838884864377236 GO:0031681 G-protein beta-subunit binding 3/1466 23/18639 0.130434782608696 1.6583723827036 0.26943707849161 0.838884864377236 GO:0140102 catalytic activity, acting on a rRNA 3/1466 23/18639 0.130434782608696 1.6583723827036 0.26943707849161 0.838884864377236 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/1466 23/18639 0.130434782608696 1.6583723827036 0.26943707849161 0.838884864377236 GO:0002020 protease binding 13/1466 136/18639 0.0955882352941176 1.21532681967739 0.272238926277728 0.838884864377236 GO:0044325 transmembrane transporter binding 13/1466 136/18639 0.0955882352941176 1.21532681967739 0.272238926277728 0.838884864377236 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0004993 G protein-coupled serotonin receptor activity 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0005035 death receptor activity 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0008035 high-density lipoprotein particle binding 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0031994 insulin-like growth factor I binding 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0035673 oligopeptide transmembrane transporter activity 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0070700 BMP receptor binding 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:1901338 catecholamine binding 2/1466 13/18639 0.153846153846154 1.9560289642145 0.272647484637908 0.838884864377236 GO:0015020 glucuronosyltransferase activity 4/1466 34/18639 0.117647058823529 1.49578685498756 0.277006438021026 0.838884864377236 GO:0019825 oxygen binding 4/1466 34/18639 0.117647058823529 1.49578685498756 0.277006438021026 0.838884864377236 GO:0141110 transporter inhibitor activity 5/1466 45/18639 0.111111111111111 1.41268758526603 0.278102542390359 0.838884864377236 GO:0016922 nuclear receptor binding 13/1466 137/18639 0.0948905109489051 1.20645582099362 0.280929285940696 0.838884864377236 GO:0030145 manganese ion binding 7/1466 68/18639 0.102941176470588 1.30881349811412 0.28580023142672 0.838884864377236 GO:0016504 peptidase activator activity 6/1466 57/18639 0.105263157894737 1.33833560709413 0.290248838695448 0.838884864377236 GO:0005540 hyaluronic acid binding 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0015149 hexose transmembrane transporter activity 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0015295 solute:proton symporter activity 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0030215 semaphorin receptor binding 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0050431 transforming growth factor beta binding 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0055056 D-glucose transmembrane transporter activity 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0060229 lipase activator activity 3/1466 24/18639 0.125 1.58927353342428 0.29148567081555 0.838884864377236 GO:0016229 steroid dehydrogenase activity 4/1466 35/18639 0.114285714285714 1.4530500877022 0.295090428769968 0.838884864377236 GO:0140566 histone reader activity 4/1466 35/18639 0.114285714285714 1.4530500877022 0.295090428769968 0.838884864377236 GO:0030295 protein kinase activator activity 13/1466 139/18639 0.0935251798561151 1.18909674443256 0.298563515775609 0.838884864377236 GO:0003735 structural constituent of ribosome 16/1466 175/18639 0.0914285714285714 1.16244007016176 0.301831712438477 0.838884864377236 GO:0005344 oxygen carrier activity 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0005347 ATP transmembrane transporter activity 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0008331 high voltage-gated calcium channel activity 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0008494 translation activator activity 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0030983 mismatched DNA binding 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0032036 myosin heavy chain binding 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0070742 C2H2 zinc finger domain binding 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0071933 Arp2/3 complex binding 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:1990825 sequence-specific mRNA binding 2/1466 14/18639 0.142857142857143 1.81631260962775 0.30275007289742 0.838884864377236 GO:0033192 calmodulin-dependent protein phosphatase activity 8/1466 81/18639 0.0987654320987654 1.25572229801425 0.304335149395808 0.838884864377236 GO:0140791 histone H2AXS140 phosphatase activity 8/1466 81/18639 0.0987654320987654 1.25572229801425 0.304335149395808 0.838884864377236 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 8/1466 81/18639 0.0987654320987654 1.25572229801425 0.304335149395808 0.838884864377236 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 8/1466 81/18639 0.0987654320987654 1.25572229801425 0.304335149395808 0.838884864377236 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 8/1466 81/18639 0.0987654320987654 1.25572229801425 0.304335149395808 0.838884864377236 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 8/1466 81/18639 0.0987654320987654 1.25572229801425 0.304335149395808 0.838884864377236 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 8/1466 81/18639 0.0987654320987654 1.25572229801425 0.304335149395808 0.838884864377236 GO:1990439 MAP kinase serine/threonine phosphatase activity 8/1466 81/18639 0.0987654320987654 1.25572229801425 0.304335149395808 0.838884864377236 GO:0004713 protein tyrosine kinase activity 13/1466 140/18639 0.0928571428571429 1.18060319625804 0.307496624625643 0.838884864377236 GO:0099095 ligand-gated monoatomic anion channel activity 5/1466 47/18639 0.106382978723404 1.35257321993556 0.309473588434418 0.838884864377236 GO:0004033 aldo-keto reductase (NADPH) activity 4/1466 36/18639 0.111111111111111 1.41268758526603 0.313315427307987 0.838884864377236 GO:0004190 aspartic-type endopeptidase activity 4/1466 36/18639 0.111111111111111 1.41268758526603 0.313315427307987 0.838884864377236 GO:0005484 SNAP receptor activity 4/1466 36/18639 0.111111111111111 1.41268758526603 0.313315427307987 0.838884864377236 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/1466 36/18639 0.111111111111111 1.41268758526603 0.313315427307987 0.838884864377236 GO:0045505 dynein intermediate chain binding 4/1466 36/18639 0.111111111111111 1.41268758526603 0.313315427307987 0.838884864377236 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/1466 36/18639 0.111111111111111 1.41268758526603 0.313315427307987 0.838884864377236 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/1466 36/18639 0.111111111111111 1.41268758526603 0.313315427307987 0.838884864377236 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/1466 36/18639 0.111111111111111 1.41268758526603 0.313315427307987 0.838884864377236 GO:0008483 transaminase activity 3/1466 25/18639 0.12 1.52570259208731 0.313648293658725 0.838884864377236 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/1466 25/18639 0.12 1.52570259208731 0.313648293658725 0.838884864377236 GO:0019211 phosphatase activator activity 3/1466 25/18639 0.12 1.52570259208731 0.313648293658725 0.838884864377236 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 3/1466 25/18639 0.12 1.52570259208731 0.313648293658725 0.838884864377236 GO:0120020 cholesterol transfer activity 3/1466 25/18639 0.12 1.52570259208731 0.313648293658725 0.838884864377236 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 8/1466 82/18639 0.0975609756097561 1.2404086114531 0.316221437745195 0.838884864377236 GO:0033549 MAP kinase phosphatase activity 8/1466 82/18639 0.0975609756097561 1.2404086114531 0.316221437745195 0.838884864377236 GO:0044389 ubiquitin-like protein ligase binding 28/1466 322/18639 0.0869565217391304 1.10558158846907 0.316924037550025 0.838884864377236 GO:0015459 potassium channel regulator activity 6/1466 59/18639 0.101694915254237 1.29296829837908 0.318405796040738 0.838884864377236 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 12/1466 130/18639 0.0923076923076923 1.1736173785287 0.32487018719768 0.838884864377236 GO:0020037 heme binding 13/1466 142/18639 0.0915492957746479 1.16397498222624 0.325567471447632 0.838884864377236 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 8/1466 83/18639 0.0963855421686747 1.2254639293874 0.328196059252167 0.838884864377236 GO:0005254 chloride channel activity 8/1466 83/18639 0.0963855421686747 1.2254639293874 0.328196059252167 0.838884864377236 GO:0043394 proteoglycan binding 4/1466 37/18639 0.108108108108108 1.3745068397183 0.331634742370966 0.838884864377236 GO:0070001 aspartic-type peptidase activity 4/1466 37/18639 0.108108108108108 1.3745068397183 0.331634742370966 0.838884864377236 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0008242 omega peptidase activity 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0017081 chloride channel regulator activity 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0031005 filamin binding 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0031386 protein tag activity 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0033130 acetylcholine receptor binding 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0034483 heparan sulfate sulfotransferase activity 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0042809 nuclear vitamin D receptor binding 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0045504 dynein heavy chain binding 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0050780 dopamine receptor binding 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0140776 protein-containing complex destabilizing activity 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0141047 molecular tag activity 2/1466 15/18639 0.133333333333333 1.69522510231924 0.332620046009246 0.838884864377236 GO:0031072 heat shock protein binding 12/1466 131/18639 0.0916030534351145 1.16465846724222 0.334410482332168 0.838884864377236 GO:0004529 DNA exonuclease activity 3/1466 26/18639 0.115384615384615 1.46702172316088 0.335844720400592 0.838884864377236 GO:0005112 Notch binding 3/1466 26/18639 0.115384615384615 1.46702172316088 0.335844720400592 0.838884864377236 GO:0008198 ferrous iron binding 3/1466 26/18639 0.115384615384615 1.46702172316088 0.335844720400592 0.838884864377236 GO:0015145 monosaccharide transmembrane transporter activity 3/1466 26/18639 0.115384615384615 1.46702172316088 0.335844720400592 0.838884864377236 GO:0015216 purine nucleotide transmembrane transporter activity 3/1466 26/18639 0.115384615384615 1.46702172316088 0.335844720400592 0.838884864377236 GO:0019865 immunoglobulin binding 3/1466 26/18639 0.115384615384615 1.46702172316088 0.335844720400592 0.838884864377236 GO:0050681 nuclear androgen receptor binding 3/1466 26/18639 0.115384615384615 1.46702172316088 0.335844720400592 0.838884864377236 GO:0050750 low-density lipoprotein particle receptor binding 3/1466 26/18639 0.115384615384615 1.46702172316088 0.335844720400592 0.838884864377236 GO:0052742 phosphatidylinositol kinase activity 3/1466 26/18639 0.115384615384615 1.46702172316088 0.335844720400592 0.838884864377236 GO:0017018 myosin phosphatase activity 8/1466 84/18639 0.0952380952380952 1.21087507308517 0.340246064724702 0.848043107326794 GO:0016763 pentosyltransferase activity 5/1466 49/18639 0.102040816326531 1.29736614973411 0.341294827088502 0.848823772543387 GO:0015026 coreceptor activity 6/1466 61/18639 0.0983606557377049 1.25057589515353 0.346944096967547 0.857330809208885 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 6/1466 61/18639 0.0983606557377049 1.25057589515353 0.346944096967547 0.857330809208885 GO:0019905 syntaxin binding 6/1466 61/18639 0.0983606557377049 1.25057589515353 0.346944096967547 0.857330809208885 GO:0005109 frizzled binding 4/1466 38/18639 0.105263157894737 1.33833560709413 0.350003645187614 0.860539011910939 GO:0004521 RNA endonuclease activity 7/1466 73/18639 0.0958904109589041 1.21916873796931 0.350344543777942 0.860539011910939 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 16/1466 181/18639 0.0883977900552486 1.12390614518402 0.350479493585911 0.860539011910939 GO:0005017 platelet-derived growth factor receptor activity 5/1466 50/18639 0.1 1.27141882673943 0.357299374933817 0.863772319489922 GO:0005019 platelet-derived growth factor beta-receptor activity 5/1466 50/18639 0.1 1.27141882673943 0.357299374933817 0.863772319489922 GO:0032813 tumor necrosis factor receptor superfamily binding 5/1466 50/18639 0.1 1.27141882673943 0.357299374933817 0.863772319489922 GO:0005044 scavenger receptor activity 3/1466 27/18639 0.111111111111111 1.41268758526603 0.358000800121305 0.863772319489922 GO:0005104 fibroblast growth factor receptor binding 3/1466 27/18639 0.111111111111111 1.41268758526603 0.358000800121305 0.863772319489922 GO:0005385 zinc ion transmembrane transporter activity 3/1466 27/18639 0.111111111111111 1.41268758526603 0.358000800121305 0.863772319489922 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/1466 27/18639 0.111111111111111 1.41268758526603 0.358000800121305 0.863772319489922 GO:0035255 ionotropic glutamate receptor binding 3/1466 27/18639 0.111111111111111 1.41268758526603 0.358000800121305 0.863772319489922 GO:0004708 MAP kinase kinase activity 2/1466 16/18639 0.125 1.58927353342428 0.362107846232399 0.863772319489922 GO:0015562 efflux transmembrane transporter activity 2/1466 16/18639 0.125 1.58927353342428 0.362107846232399 0.863772319489922 GO:0016722 oxidoreductase activity, acting on metal ions 2/1466 16/18639 0.125 1.58927353342428 0.362107846232399 0.863772319489922 GO:0017070 U6 snRNA binding 2/1466 16/18639 0.125 1.58927353342428 0.362107846232399 0.863772319489922 GO:0019841 retinol binding 2/1466 16/18639 0.125 1.58927353342428 0.362107846232399 0.863772319489922 GO:0031491 nucleosome binding 7/1466 74/18639 0.0945945945945946 1.20269348475351 0.3634724346999 0.863772319489922 GO:0005516 calmodulin binding 18/1466 207/18639 0.0869565217391304 1.10558158846907 0.363763262338619 0.863772319489922 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 11/1466 122/18639 0.0901639344262295 1.14636123722407 0.364128365387479 0.863772319489922 GO:0050660 flavin adenine dinucleotide binding 8/1466 86/18639 0.0930232558139535 1.18271518766458 0.364520900859265 0.863772319489922 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/1466 39/18639 0.102564102564103 1.30401930947634 0.368379517090401 0.867571352494536 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/1466 39/18639 0.102564102564103 1.30401930947634 0.368379517090401 0.867571352494536 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/1466 39/18639 0.102564102564103 1.30401930947634 0.368379517090401 0.867571352494536 GO:0099106 ion channel regulator activity 14/1466 160/18639 0.0875 1.112491473397 0.379159773713403 0.878047730398187 GO:0019789 SUMO transferase activity 3/1466 28/18639 0.107142857142857 1.36223445722081 0.380048456473172 0.878047730398187 GO:0036408 histone H3K14 acetyltransferase activity 3/1466 28/18639 0.107142857142857 1.36223445722081 0.380048456473172 0.878047730398187 GO:0046625 sphingolipid binding 3/1466 28/18639 0.107142857142857 1.36223445722081 0.380048456473172 0.878047730398187 GO:0046875 ephrin receptor binding 3/1466 28/18639 0.107142857142857 1.36223445722081 0.380048456473172 0.878047730398187 GO:0051019 mitogen-activated protein kinase binding 3/1466 28/18639 0.107142857142857 1.36223445722081 0.380048456473172 0.878047730398187 GO:0051119 sugar transmembrane transporter activity 3/1466 28/18639 0.107142857142857 1.36223445722081 0.380048456473172 0.878047730398187 GO:0031267 small GTPase binding 24/1466 283/18639 0.0848056537102474 1.07823504741153 0.380525402787461 0.878047730398187 GO:0019209 kinase activator activity 13/1466 148/18639 0.0878378378378378 1.11678680727112 0.381016172845484 0.878047730398187 GO:0030331 nuclear estrogen receptor binding 4/1466 40/18639 0.1 1.27141882673943 0.386721963348062 0.878047730398187 GO:0004674 protein serine/threonine kinase activity 36/1466 433/18639 0.0831408775981524 1.05706877049929 0.388509784424954 0.878047730398187 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 5/1466 52/18639 0.0961538461538462 1.22251810263406 0.389354441430943 0.878047730398187 GO:0017022 myosin binding 7/1466 76/18639 0.0921052631578947 1.17104365620737 0.38981956073029 0.878047730398187 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0008429 phosphatidylethanolamine binding 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0008569 minus-end-directed microtubule motor activity 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0016805 dipeptidase activity 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0017110 nucleoside diphosphate phosphatase activity 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0030169 low-density lipoprotein particle binding 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0038191 neuropilin binding 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0046965 nuclear retinoid X receptor binding 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0051787 misfolded protein binding 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0070492 oligosaccharide binding 2/1466 17/18639 0.117647058823529 1.49578685498756 0.391088850454652 0.878047730398187 GO:0010484 histone H3 acetyltransferase activity 3/1466 29/18639 0.103448275862069 1.31526085524768 0.401925613306415 0.898880150689152 GO:0051861 glycolipid binding 3/1466 29/18639 0.103448275862069 1.31526085524768 0.401925613306415 0.898880150689152 GO:0001727 lipid kinase activity 4/1466 41/18639 0.0975609756097561 1.2404086114531 0.404992896340247 0.899568175611071 GO:0008227 G protein-coupled amine receptor activity 4/1466 41/18639 0.0975609756097561 1.2404086114531 0.404992896340247 0.899568175611071 GO:0005544 calcium-dependent phospholipid binding 5/1466 53/18639 0.0943396226415094 1.19945172333908 0.40535134429615 0.899568175611071 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1466 53/18639 0.0943396226415094 1.19945172333908 0.40535134429615 0.899568175611071 GO:0061134 peptidase regulator activity 19/1466 226/18639 0.084070796460177 1.06889193398447 0.415632392344205 0.901857518119293 GO:0017124 SH3 domain binding 10/1466 115/18639 0.0869565217391304 1.10558158846907 0.418682214713638 0.901857518119293 GO:0035401 histone H3Y41 kinase activity 10/1466 115/18639 0.0869565217391304 1.10558158846907 0.418682214713638 0.901857518119293 GO:0140801 histone H2AXY142 kinase activity 10/1466 115/18639 0.0869565217391304 1.10558158846907 0.418682214713638 0.901857518119293 GO:0008235 metalloexopeptidase activity 6/1466 66/18639 0.0909090909090909 1.15583529703584 0.418860821782711 0.901857518119293 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/1466 18/18639 0.111111111111111 1.41268758526603 0.419460377403865 0.901857518119293 GO:0004970 glutamate-gated receptor activity 2/1466 18/18639 0.111111111111111 1.41268758526603 0.419460377403865 0.901857518119293 GO:0015172 acidic amino acid transmembrane transporter activity 2/1466 18/18639 0.111111111111111 1.41268758526603 0.419460377403865 0.901857518119293 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/1466 18/18639 0.111111111111111 1.41268758526603 0.419460377403865 0.901857518119293 GO:0070064 proline-rich region binding 2/1466 18/18639 0.111111111111111 1.41268758526603 0.419460377403865 0.901857518119293 GO:0070628 proteasome binding 2/1466 18/18639 0.111111111111111 1.41268758526603 0.419460377403865 0.901857518119293 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1466 18/18639 0.111111111111111 1.41268758526603 0.419460377403865 0.901857518119293 GO:1901611 phosphatidylglycerol binding 2/1466 18/18639 0.111111111111111 1.41268758526603 0.419460377403865 0.901857518119293 GO:1990381 ubiquitin-specific protease binding 2/1466 18/18639 0.111111111111111 1.41268758526603 0.419460377403865 0.901857518119293 GO:0043021 ribonucleoprotein complex binding 15/1466 177/18639 0.0847457627118644 1.07747358198257 0.420747705300074 0.901857518119293 GO:0016859 cis-trans isomerase activity 4/1466 42/18639 0.0952380952380952 1.21087507308517 0.423156591103574 0.901857518119293 GO:0042056 chemoattractant activity 4/1466 42/18639 0.0952380952380952 1.21087507308517 0.423156591103574 0.901857518119293 GO:0015215 nucleotide transmembrane transporter activity 3/1466 30/18639 0.1 1.27141882673943 0.42357606136972 0.901857518119293 GO:0031624 ubiquitin conjugating enzyme binding 3/1466 30/18639 0.1 1.27141882673943 0.42357606136972 0.901857518119293 GO:0043995 histone H4K5 acetyltransferase activity 3/1466 30/18639 0.1 1.27141882673943 0.42357606136972 0.901857518119293 GO:0043996 histone H4K8 acetyltransferase activity 3/1466 30/18639 0.1 1.27141882673943 0.42357606136972 0.901857518119293 GO:0043997 histone H4K12 acetyltransferase activity 3/1466 30/18639 0.1 1.27141882673943 0.42357606136972 0.901857518119293 GO:0031625 ubiquitin protein ligase binding 25/1466 302/18639 0.0827814569536424 1.0524990287578 0.424852355843368 0.902909058274855 GO:0072341 modified amino acid binding 8/1466 91/18639 0.0879120879120879 1.117730836694 0.425646048997712 0.902932978939998 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 14/1466 167/18639 0.0838323353293413 1.06586009427257 0.442373761760884 0.931405087673726 GO:0070325 lipoprotein particle receptor binding 3/1466 31/18639 0.0967741935483871 1.23040531619945 0.444949278389908 0.931405087673726 GO:0003756 protein disulfide isomerase activity 2/1466 19/18639 0.105263157894737 1.33833560709413 0.447139010893626 0.931405087673726 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/1466 19/18639 0.105263157894737 1.33833560709413 0.447139010893626 0.931405087673726 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1466 19/18639 0.105263157894737 1.33833560709413 0.447139010893626 0.931405087673726 GO:0015245 fatty acid transmembrane transporter activity 2/1466 19/18639 0.105263157894737 1.33833560709413 0.447139010893626 0.931405087673726 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/1466 19/18639 0.105263157894737 1.33833560709413 0.447139010893626 0.931405087673726 GO:0030506 ankyrin binding 2/1466 19/18639 0.105263157894737 1.33833560709413 0.447139010893626 0.931405087673726 GO:0043395 heparan sulfate proteoglycan binding 2/1466 19/18639 0.105263157894737 1.33833560709413 0.447139010893626 0.931405087673726 GO:0099589 serotonin receptor activity 2/1466 19/18639 0.105263157894737 1.33833560709413 0.447139010893626 0.931405087673726 GO:0051213 dioxygenase activity 8/1466 93/18639 0.0860215053763441 1.09369361439951 0.450021527310564 0.933097363889467 GO:0030170 pyridoxal phosphate binding 5/1466 56/18639 0.0892857142857143 1.13519538101735 0.452922265586641 0.933097363889467 GO:0000149 SNARE binding 9/1466 106/18639 0.0849056603773585 1.07950655100517 0.456389349508104 0.933097363889467 GO:0004497 monooxygenase activity 9/1466 106/18639 0.0849056603773585 1.07950655100517 0.456389349508104 0.933097363889467 GO:0001046 core promoter sequence-specific DNA binding 4/1466 44/18639 0.0909090909090909 1.15583529703584 0.459031342400685 0.933097363889467 GO:0001223 transcription coactivator binding 4/1466 44/18639 0.0909090909090909 1.15583529703584 0.459031342400685 0.933097363889467 GO:0016790 thiolester hydrolase activity 4/1466 44/18639 0.0909090909090909 1.15583529703584 0.459031342400685 0.933097363889467 GO:0043014 alpha-tubulin binding 4/1466 44/18639 0.0909090909090909 1.15583529703584 0.459031342400685 0.933097363889467 GO:0002039 p53 binding 6/1466 69/18639 0.0869565217391304 1.10558158846907 0.461633508992809 0.933097363889467 GO:0022884 macromolecule transmembrane transporter activity 3/1466 32/18639 0.09375 1.19195515006821 0.466000213064177 0.933097363889467 GO:0120015 sterol transfer activity 3/1466 32/18639 0.09375 1.19195515006821 0.466000213064177 0.933097363889467 GO:0015932 nucleobase-containing compound transmembrane transporter activity 5/1466 57/18639 0.087719298245614 1.11527967257844 0.468563941249255 0.933097363889467 GO:0070279 vitamin B6 binding 5/1466 57/18639 0.087719298245614 1.11527967257844 0.468563941249255 0.933097363889467 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/1466 20/18639 0.1 1.27141882673943 0.474058207954301 0.933097363889467 GO:0005326 neurotransmitter transmembrane transporter activity 2/1466 20/18639 0.1 1.27141882673943 0.474058207954301 0.933097363889467 GO:0016408 C-acyltransferase activity 2/1466 20/18639 0.1 1.27141882673943 0.474058207954301 0.933097363889467 GO:0052745 inositol phosphate phosphatase activity 2/1466 20/18639 0.1 1.27141882673943 0.474058207954301 0.933097363889467 GO:0046915 transition metal ion transmembrane transporter activity 4/1466 45/18639 0.0888888888888889 1.13015006821282 0.476682932645595 0.933097363889467 GO:0005496 steroid binding 9/1466 108/18639 0.0833333333333333 1.05951568894952 0.479072956581876 0.933097363889467 GO:0051082 unfolded protein binding 10/1466 121/18639 0.0826446280991736 1.05075936094168 0.483302659548664 0.933097363889467 GO:0016407 acetyltransferase activity 8/1466 96/18639 0.0833333333333333 1.05951568894952 0.486229423464955 0.933097363889467 GO:0019956 chemokine binding 3/1466 33/18639 0.0909090909090909 1.15583529703584 0.486689041945388 0.933097363889467 GO:0042923 neuropeptide binding 3/1466 33/18639 0.0909090909090909 1.15583529703584 0.486689041945388 0.933097363889467 GO:0051117 ATPase binding 7/1466 84/18639 0.0833333333333333 1.05951568894952 0.494288517386369 0.933097363889467 GO:0001216 DNA-binding transcription activator activity 39/1466 491/18639 0.0794297352342159 1.0098846077971 0.498966185065135 0.933097363889467 GO:0001786 phosphatidylserine binding 5/1466 59/18639 0.0847457627118644 1.07747358198257 0.499402160668428 0.933097363889467 GO:0031593 polyubiquitin modification-dependent protein binding 5/1466 59/18639 0.0847457627118644 1.07747358198257 0.499402160668428 0.933097363889467 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1466 21/18639 0.0952380952380952 1.21087507308517 0.500166163640535 0.933097363889467 GO:0005248 voltage-gated sodium channel activity 2/1466 21/18639 0.0952380952380952 1.21087507308517 0.500166163640535 0.933097363889467 GO:0015174 basic amino acid transmembrane transporter activity 2/1466 21/18639 0.0952380952380952 1.21087507308517 0.500166163640535 0.933097363889467 GO:0051428 peptide hormone receptor binding 2/1466 21/18639 0.0952380952380952 1.21087507308517 0.500166163640535 0.933097363889467 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 3/1466 34/18639 0.0882352941176471 1.12184014124067 0.506980906841294 0.933097363889467 GO:0051427 hormone receptor binding 3/1466 34/18639 0.0882352941176471 1.12184014124067 0.506980906841294 0.933097363889467 GO:0061733 protein-lysine-acetyltransferase activity 4/1466 47/18639 0.0851063829787234 1.08205857594845 0.511283637679954 0.933097363889467 GO:0051020 GTPase binding 25/1466 315/18639 0.0793650793650794 1.00906256090431 0.511721942140343 0.933097363889467 GO:0004714 transmembrane receptor protein tyrosine kinase activity 5/1466 60/18639 0.0833333333333333 1.05951568894952 0.514562532358718 0.933097363889467 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 5/1466 60/18639 0.0833333333333333 1.05951568894952 0.514562532358718 0.933097363889467 GO:0043539 protein serine/threonine kinase activator activity 6/1466 73/18639 0.0821917808219178 1.04500177540227 0.517284559433466 0.933097363889467 GO:0043022 ribosome binding 9/1466 112/18639 0.0803571428571429 1.02167584291561 0.523710687179147 0.933097363889467 GO:0016881 acid-amino acid ligase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0032931 histone H3K56 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0034062 5'-3' RNA polymerase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0043992 histone H3K9 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0043993 histone H3K18 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0043994 histone H3K23 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0043999 histone H2AK5 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0044012 histone H2AK9 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0044014 histone H2BK5 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0044015 histone H2BK12 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0044016 histone H3K4 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0044017 histone H3K27 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0044018 histone H3K36 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0046972 histone H4K16 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0050321 tau-protein kinase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0070034 telomerase RNA binding 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0097747 RNA polymerase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0140908 histone H3K122 acetyltransferase activity 2/1466 22/18639 0.0909090909090909 1.15583529703584 0.525423906976755 0.933097363889467 GO:0010485 histone H4 acetyltransferase activity 3/1466 35/18639 0.0857142857142857 1.08978756577665 0.526845639160482 0.933097363889467 GO:0034061 DNA polymerase activity 3/1466 35/18639 0.0857142857142857 1.08978756577665 0.526845639160482 0.933097363889467 GO:0043015 gamma-tubulin binding 3/1466 35/18639 0.0857142857142857 1.08978756577665 0.526845639160482 0.933097363889467 GO:0016741 transferase activity, transferring one-carbon groups 17/1466 215/18639 0.0790697674418605 1.0053079095149 0.527710639482892 0.933097363889467 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1466 48/18639 0.0833333333333333 1.05951568894952 0.528187321295468 0.933097363889467 GO:0140693 molecular condensate scaffold activity 4/1466 48/18639 0.0833333333333333 1.05951568894952 0.528187321295468 0.933097363889467 GO:0035064 methylated histone binding 6/1466 74/18639 0.0810810810810811 1.03088012978872 0.530856217498193 0.933097363889467 GO:0140767 enzyme-substrate adaptor activity 11/1466 139/18639 0.079136690647482 1.00615878375063 0.537060366889703 0.933097363889467 GO:0008168 methyltransferase activity 16/1466 204/18639 0.0784313725490196 0.997191236658374 0.542531723895947 0.933097363889467 GO:0019003 GDP binding 6/1466 75/18639 0.08 1.01713506139154 0.544266677127766 0.933097363889467 GO:0005004 GPI-linked ephrin receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0005008 hepatocyte growth factor receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0005009 insulin receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0005011 macrophage colony-stimulating factor receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0005020 stem cell factor receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0008288 boss receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0035254 glutamate receptor binding 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0036332 placental growth factor receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0038062 protein tyrosine kinase collagen receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0060175 brain-derived neurotrophic factor receptor activity 4/1466 49/18639 0.0816326530612245 1.03789291978729 0.544799987447198 0.933097363889467 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0008171 O-methyltransferase activity 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0016849 phosphorus-oxygen lyase activity 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0017134 fibroblast growth factor binding 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0043274 phospholipase binding 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0044013 histone H2B acetyltransferase activity 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0071617 lysophospholipid acyltransferase activity 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0140103 catalytic activity, acting on a glycoprotein 2/1466 23/18639 0.0869565217391304 1.10558158846907 0.549803604927721 0.933097363889467 GO:0001221 transcription coregulator binding 9/1466 115/18639 0.0782608695652174 0.99502342962216 0.556315319457848 0.933097363889467 GO:0015171 amino acid transmembrane transporter activity 8/1466 102/18639 0.0784313725490196 0.997191236658374 0.556417272960638 0.933097363889467 GO:0140034 methylation-dependent protein binding 6/1466 76/18639 0.0789473684210526 1.0037517053206 0.557505001390407 0.933097363889467 GO:0000182 rDNA binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0005131 growth hormone receptor binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0005381 iron ion transmembrane transporter activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0005522 profilin binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0008401 retinoic acid 4-hydroxylase activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0015187 glycine transmembrane transporter activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0015279 store-operated calcium channel activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0030957 Tat protein binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0031434 mitogen-activated protein kinase kinase binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0031720 haptoglobin binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0035256 G protein-coupled glutamate receptor binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0042166 acetylcholine binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0043121 neurotrophin binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0043208 glycosphingolipid binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0043295 glutathione binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0050815 phosphoserine residue binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0070513 death domain binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0097177 mitochondrial ribosome binding 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0140940 histone H2A methyltransferase activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:1990259 histone H2AQ104 methyltransferase activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:1990757 ubiquitin ligase activator activity 1/1466 10/18639 0.1 1.27141882673943 0.55929692974621 0.933097363889467 GO:0005006 epidermal growth factor receptor activity 4/1466 50/18639 0.08 1.01713506139154 0.561104388535319 0.933097363889467 GO:0005007 fibroblast growth factor receptor activity 4/1466 50/18639 0.08 1.01713506139154 0.561104388535319 0.933097363889467 GO:0019001 guanyl nucleotide binding 31/1466 400/18639 0.0775 0.985349590723056 0.5618852703232 0.933097363889467 GO:0032561 guanyl ribonucleotide binding 31/1466 400/18639 0.0775 0.985349590723056 0.5618852703232 0.933097363889467 GO:0030551 cyclic nucleotide binding 3/1466 37/18639 0.0810810810810811 1.03088012978872 0.565194776680793 0.933097363889467 GO:0042805 actinin binding 3/1466 37/18639 0.0810810810810811 1.03088012978872 0.565194776680793 0.933097363889467 GO:0005201 extracellular matrix structural constituent 13/1466 168/18639 0.0773809523809524 0.9838359968817 0.566158085679326 0.933097363889467 GO:0004722 protein serine/threonine phosphatase activity 8/1466 103/18639 0.0776699029126214 0.987509768341302 0.567728564903328 0.933097363889467 GO:0005253 monoatomic anion channel activity 8/1466 103/18639 0.0776699029126214 0.987509768341302 0.567728564903328 0.933097363889467 GO:0051540 metal cluster binding 6/1466 77/18639 0.0779220779220779 0.990715968887865 0.57056106896513 0.933097363889467 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/1466 24/18639 0.0833333333333333 1.05951568894952 0.573287053483373 0.933097363889467 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1466 24/18639 0.0833333333333333 1.05951568894952 0.573287053483373 0.933097363889467 GO:0030552 cAMP binding 2/1466 24/18639 0.0833333333333333 1.05951568894952 0.573287053483373 0.933097363889467 GO:0035035 histone acetyltransferase binding 2/1466 24/18639 0.0833333333333333 1.05951568894952 0.573287053483373 0.933097363889467 GO:0043998 histone H2A acetyltransferase activity 2/1466 24/18639 0.0833333333333333 1.05951568894952 0.573287053483373 0.933097363889467 GO:0050699 WW domain binding 2/1466 24/18639 0.0833333333333333 1.05951568894952 0.573287053483373 0.933097363889467 GO:0070300 phosphatidic acid binding 2/1466 24/18639 0.0833333333333333 1.05951568894952 0.573287053483373 0.933097363889467 GO:0030414 peptidase inhibitor activity 13/1466 169/18639 0.0769230769230769 0.978014482107252 0.574968050087493 0.933097363889467 GO:0140375 immune receptor activity 12/1466 156/18639 0.0769230769230769 0.978014482107252 0.575307708668712 0.933097363889467 GO:0005010 insulin-like growth factor receptor activity 4/1466 51/18639 0.0784313725490196 0.997191236658374 0.577085326554957 0.933097363889467 GO:0005021 vascular endothelial growth factor receptor activity 4/1466 51/18639 0.0784313725490196 0.997191236658374 0.577085326554957 0.933097363889467 GO:0005030 neurotrophin receptor activity 4/1466 51/18639 0.0784313725490196 0.997191236658374 0.577085326554957 0.933097363889467 GO:0005272 sodium channel activity 4/1466 51/18639 0.0784313725490196 0.997191236658374 0.577085326554957 0.933097363889467 GO:0004518 nuclease activity 16/1466 209/18639 0.076555023923445 0.973334986977552 0.58254810191566 0.933097363889467 GO:0005525 GTP binding 29/1466 378/18639 0.0767195767195767 0.975427142207497 0.584211967303854 0.933097363889467 GO:0019843 rRNA binding 5/1466 65/18639 0.0769230769230769 0.978014482107252 0.587169516948182 0.933097363889467 GO:0061135 endopeptidase regulator activity 14/1466 184/18639 0.0760869565217391 0.967383889910434 0.591547910324131 0.933097363889467 GO:0030159 signaling receptor complex adaptor activity 4/1466 52/18639 0.0769230769230769 0.978014482107252 0.592729566981958 0.933097363889467 GO:0001851 complement component C3b binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0003953 NAD+ nucleosidase activity 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0005114 type II transforming growth factor beta receptor binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0005536 D-glucose binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0008172 S-methyltransferase activity 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0008526 phosphatidylinositol transfer activity 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0019215 intermediate filament binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0019864 IgG binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0032050 clathrin heavy chain binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0032404 mismatch repair complex binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0034056 estrogen response element binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0034511 U3 snoRNA binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0034713 type I transforming growth factor beta receptor binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0035252 UDP-xylosyltransferase activity 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0042285 xylosyltransferase activity 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0048185 activin binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0050998 nitric-oxide synthase binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0070990 snRNP binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0097493 structural molecule activity conferring elasticity 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0140031 phosphorylation-dependent protein binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:1900750 oligopeptide binding 1/1466 11/18639 0.0909090909090909 1.15583529703584 0.593977841281561 0.933097363889467 GO:0003707 nuclear steroid receptor activity 2/1466 25/18639 0.08 1.01713506139154 0.595864336946386 0.933097363889467 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1466 25/18639 0.08 1.01713506139154 0.595864336946386 0.933097363889467 GO:0017025 TBP-class protein binding 2/1466 25/18639 0.08 1.01713506139154 0.595864336946386 0.933097363889467 GO:0046332 SMAD binding 6/1466 79/18639 0.0759493670886076 0.965634551953995 0.596089964571404 0.933097363889467 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 37/1466 484/18639 0.0764462809917355 0.971952408871049 0.597478406382045 0.933097363889467 GO:0005003 ephrin receptor activity 4/1466 53/18639 0.0754716981132075 0.959561378671266 0.608025748425698 0.933097363889467 GO:0005005 transmembrane-ephrin receptor activity 4/1466 53/18639 0.0754716981132075 0.959561378671266 0.608025748425698 0.933097363889467 GO:0005246 calcium channel regulator activity 4/1466 53/18639 0.0754716981132075 0.959561378671266 0.608025748425698 0.933097363889467 GO:0034212 protein N-acetyltransferase activity 4/1466 53/18639 0.0754716981132075 0.959561378671266 0.608025748425698 0.933097363889467 GO:0015276 ligand-gated monoatomic ion channel activity 14/1466 186/18639 0.0752688172043011 0.956981912599569 0.608045560208693 0.933097363889467 GO:0048306 calcium-dependent protein binding 6/1466 80/18639 0.075 0.95356412005457 0.60854652504053 0.933097363889467 GO:0140030 modification-dependent protein binding 13/1466 173/18639 0.0751445086705202 0.955401430497835 0.609448650373346 0.933097363889467 GO:0016500 protein-hormone receptor activity 5/1466 67/18639 0.0746268656716418 0.948820019954796 0.614495931135013 0.933097363889467 GO:0004435 phosphatidylinositol phospholipase C activity 2/1466 26/18639 0.0769230769230769 0.978014482107252 0.617532638325202 0.933097363889467 GO:0008066 glutamate receptor activity 2/1466 26/18639 0.0769230769230769 0.978014482107252 0.617532638325202 0.933097363889467 GO:0097602 cullin family protein binding 2/1466 26/18639 0.0769230769230769 0.978014482107252 0.617532638325202 0.933097363889467 GO:0015108 chloride transmembrane transporter activity 9/1466 121/18639 0.0743801652892562 0.945683424847508 0.618540769858305 0.933097363889467 GO:0015144 carbohydrate transmembrane transporter activity 3/1466 40/18639 0.075 0.95356412005457 0.618998848325268 0.933097363889467 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/1466 40/18639 0.075 0.95356412005457 0.618998848325268 0.933097363889467 GO:0061791 GTPase motor activity 3/1466 40/18639 0.075 0.95356412005457 0.618998848325268 0.933097363889467 GO:1990606 membrane scission GTPase motor activity 3/1466 40/18639 0.075 0.95356412005457 0.618998848325268 0.933097363889467 GO:0030971 receptor tyrosine kinase binding 6/1466 81/18639 0.0740740740740741 0.941791723510687 0.620788260907712 0.933097363889467 GO:0140463 chromatin-protein adaptor activity 4/1466 54/18639 0.0740740740740741 0.941791723510687 0.622964289247023 0.933097363889467 GO:0022834 ligand-gated channel activity 14/1466 188/18639 0.074468085106383 0.946801253954892 0.6242327909548 0.933097363889467 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0004000 adenosine deaminase activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0004032 aldose reductase (NADPH) activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0004300 enoyl-CoA hydratase activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0004859 phospholipase inhibitor activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0005049 nuclear export signal receptor activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0005095 GTPase inhibitor activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0005165 neurotrophin receptor binding 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0008504 monoamine transmembrane transporter activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0015166 polyol transmembrane transporter activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0015269 calcium-activated potassium channel activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0016423 tRNA (guanine) methyltransferase activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0034452 dynactin binding 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0035251 UDP-glucosyltransferase activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0036009 protein-glutamine N-methyltransferase activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/1466 12/18639 0.0833333333333333 1.05951568894952 0.625931270779158 0.933097363889467 GO:0008509 monoatomic anion transmembrane transporter activity 11/1466 149/18639 0.0738255033557047 0.938631348599577 0.63118143540407 0.933097363889467 GO:0035173 histone kinase activity 27/1466 360/18639 0.075 0.95356412005457 0.631242485264503 0.933097363889467 GO:0099094 ligand-gated monoatomic cation channel activity 10/1466 136/18639 0.0735294117647059 0.934866784367226 0.63439133383925 0.933097363889467 GO:0001530 lipopolysaccharide binding 3/1466 41/18639 0.0731707317073171 0.930306458589825 0.635894055060928 0.933097363889467 GO:0042169 SH2 domain binding 3/1466 41/18639 0.0731707317073171 0.930306458589825 0.635894055060928 0.933097363889467 GO:0008374 O-acyltransferase activity 4/1466 55/18639 0.0727272727272727 0.924668237628674 0.637537292208627 0.933097363889467 GO:0004896 cytokine receptor activity 7/1466 96/18639 0.0729166666666667 0.927076227830832 0.637906719685462 0.933097363889467 GO:0001671 ATPase activator activity 2/1466 27/18639 0.0740740740740741 0.941791723510687 0.638295185381514 0.933097363889467 GO:0008320 protein transmembrane transporter activity 2/1466 27/18639 0.0740740740740741 0.941791723510687 0.638295185381514 0.933097363889467 GO:0008395 steroid hydroxylase activity 2/1466 27/18639 0.0740740740740741 0.941791723510687 0.638295185381514 0.933097363889467 GO:0008080 N-acetyltransferase activity 5/1466 69/18639 0.072463768115942 0.921317990390889 0.640731780928985 0.933097363889467 GO:0008135 translation factor activity, RNA binding 6/1466 83/18639 0.072289156626506 0.91909794704055 0.644603002015587 0.933097363889467 GO:0004402 histone acetyltransferase activity 3/1466 42/18639 0.0714285714285714 0.908156304813876 0.652258475365339 0.933097363889467 GO:0051879 Hsp90 protein binding 3/1466 42/18639 0.0714285714285714 0.908156304813876 0.652258475365339 0.933097363889467 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1466 70/18639 0.0714285714285714 0.908156304813876 0.653424678218062 0.933097363889467 GO:0015103 inorganic anion transmembrane transporter activity 12/1466 165/18639 0.0727272727272727 0.924668237628674 0.653761289200315 0.933097363889467 GO:0003964 RNA-directed DNA polymerase activity 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0005542 folic acid binding 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0008253 5'-nucleotidase activity 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0008417 fucosyltransferase activity 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0017154 semaphorin receptor activity 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0031432 titin binding 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0046975 histone H3K36 methyltransferase activity 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0051011 microtubule minus-end binding 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0061459 L-arginine transmembrane transporter activity 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0071837 HMG box domain binding 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0089720 caspase binding 1/1466 13/18639 0.0769230769230769 0.978014482107252 0.655371586290928 0.933097363889467 GO:0180051 translation factor activity 6/1466 84/18639 0.0714285714285714 0.908156304813876 0.656165654679373 0.933097363889467 GO:0016866 intramolecular transferase activity 2/1466 28/18639 0.0714285714285714 0.908156304813876 0.658160318374463 0.933097363889467 GO:0046966 nuclear thyroid hormone receptor binding 2/1466 28/18639 0.0714285714285714 0.908156304813876 0.658160318374463 0.933097363889467 GO:0050698 proteoglycan sulfotransferase activity 2/1466 28/18639 0.0714285714285714 0.908156304813876 0.658160318374463 0.933097363889467 GO:0051393 alpha-actinin binding 2/1466 28/18639 0.0714285714285714 0.908156304813876 0.658160318374463 0.933097363889467 GO:0051959 dynein light intermediate chain binding 2/1466 28/18639 0.0714285714285714 0.908156304813876 0.658160318374463 0.933097363889467 GO:0008170 N-methyltransferase activity 7/1466 98/18639 0.0714285714285714 0.908156304813876 0.659449532751303 0.933097363889467 GO:0070851 growth factor receptor binding 10/1466 139/18639 0.0719424460431655 0.91468980340966 0.661677948943626 0.933097363889467 GO:0005245 voltage-gated calcium channel activity 3/1466 43/18639 0.0697674418604651 0.887036390748437 0.668089382305737 0.933097363889467 GO:0008375 acetylglucosaminyltransferase activity 3/1466 43/18639 0.0697674418604651 0.887036390748437 0.668089382305737 0.933097363889467 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1466 43/18639 0.0697674418604651 0.887036390748437 0.668089382305737 0.933097363889467 GO:0048156 tau protein binding 3/1466 43/18639 0.0697674418604651 0.887036390748437 0.668089382305737 0.933097363889467 GO:0141003 histone H2AX kinase activity 26/1466 354/18639 0.0734463276836158 0.933810437718223 0.672049206694404 0.933097363889467 GO:0005261 monoatomic cation channel activity 25/1466 341/18639 0.0733137829912024 0.932125239545034 0.673403959156714 0.933097363889467 GO:0003785 actin monomer binding 2/1466 29/18639 0.0689655172413793 0.876840570165122 0.677140666898022 0.933097363889467 GO:0004181 metallocarboxypeptidase activity 2/1466 29/18639 0.0689655172413793 0.876840570165122 0.677140666898022 0.933097363889467 GO:0004629 phospholipase C activity 2/1466 29/18639 0.0689655172413793 0.876840570165122 0.677140666898022 0.933097363889467 GO:0005416 amino acid:monoatomic cation symporter activity 2/1466 29/18639 0.0689655172413793 0.876840570165122 0.677140666898022 0.933097363889467 GO:0106222 lncRNA binding 2/1466 29/18639 0.0689655172413793 0.876840570165122 0.677140666898022 0.933097363889467 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/1466 86/18639 0.0697674418604651 0.887036390748437 0.67858072293445 0.933097363889467 GO:0005216 monoatomic ion channel activity 33/1466 448/18639 0.0736607142857143 0.93653618933931 0.679989119368362 0.933097363889467 GO:0046982 protein heterodimerization activity 27/1466 369/18639 0.0731707317073171 0.930306458589825 0.681690284083378 0.933097363889467 GO:0004065 arylsulfatase activity 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0005313 L-glutamate transmembrane transporter activity 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0008392 arachidonate epoxygenase activity 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0008559 ABC-type xenobiotic transporter activity 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0016530 metallochaperone activity 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0019992 diacylglycerol binding 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0031404 chloride ion binding 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0034236 protein kinase A catalytic subunit binding 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0044548 S100 protein binding 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0046030 inositol trisphosphate phosphatase activity 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0098599 palmitoyl hydrolase activity 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:1901612 cardiolipin binding 1/1466 14/18639 0.0714285714285714 0.908156304813876 0.682496318090429 0.933097363889467 GO:0030547 signaling receptor inhibitor activity 3/1466 44/18639 0.0681818181818182 0.866876472776882 0.683386312054888 0.933097363889467 GO:0031490 chromatin DNA binding 9/1466 128/18639 0.0703125 0.89396636255116 0.684967563891836 0.933097363889467 GO:0140996 histone H3 kinase activity 26/1466 357/18639 0.0728291316526611 0.925963291182776 0.688566356001416 0.933097363889467 GO:0031210 phosphatidylcholine binding 2/1466 30/18639 0.0666666666666667 0.847612551159618 0.695252424435758 0.933097363889467 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/1466 30/18639 0.0666666666666667 0.847612551159618 0.695252424435758 0.933097363889467 GO:0048019 receptor antagonist activity 2/1466 30/18639 0.0666666666666667 0.847612551159618 0.695252424435758 0.933097363889467 GO:0051539 4 iron, 4 sulfur cluster binding 3/1466 45/18639 0.0666666666666667 0.847612551159618 0.698150839155552 0.933097363889467 GO:0015294 solute:monoatomic cation symporter activity 8/1466 116/18639 0.0689655172413793 0.876840570165122 0.701076355926037 0.933097363889467 GO:0016798 hydrolase activity, acting on glycosyl bonds 9/1466 130/18639 0.0692307692307692 0.880213033896526 0.702577641818246 0.933097363889467 GO:0019903 protein phosphatase binding 10/1466 144/18639 0.0694444444444444 0.882929740791269 0.704454486605874 0.933097363889467 GO:0004089 carbonate dehydratase activity 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0005041 low-density lipoprotein particle receptor activity 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0008252 nucleotidase activity 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0015116 sulfate transmembrane transporter activity 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0015929 hexosaminidase activity 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0016846 carbon-sulfur lyase activity 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0030553 cGMP binding 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0047372 monoacylglycerol lipase activity 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0048531 beta-1,3-galactosyltransferase activity 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0050700 CARD domain binding 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0051371 muscle alpha-actinin binding 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:0120283 protein serine/threonine kinase binding 1/1466 15/18639 0.0666666666666667 0.847612551159618 0.707487480381942 0.933097363889467 GO:1990782 protein tyrosine kinase binding 8/1466 117/18639 0.0683760683760684 0.869346206317557 0.710143509273643 0.933097363889467 GO:0004180 carboxypeptidase activity 3/1466 46/18639 0.0652173913043478 0.8291861913518 0.71238636414269 0.933097363889467 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/1466 46/18639 0.0652173913043478 0.8291861913518 0.71238636414269 0.933097363889467 GO:0030276 clathrin binding 3/1466 46/18639 0.0652173913043478 0.8291861913518 0.71238636414269 0.933097363889467 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/1466 31/18639 0.0645161290322581 0.82027021079963 0.712514710369955 0.933097363889467 GO:0016411 acylglycerol O-acyltransferase activity 2/1466 31/18639 0.0645161290322581 0.82027021079963 0.712514710369955 0.933097363889467 GO:0051536 iron-sulfur cluster binding 5/1466 76/18639 0.0657894736842105 0.836459754433834 0.723391231636524 0.933097363889467 GO:0140359 ABC-type transporter activity 3/1466 47/18639 0.0638297872340425 0.811543931961336 0.72609791367424 0.933097363889467 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 17/1466 243/18639 0.0699588477366255 0.889469961093426 0.727850900583845 0.933097363889467 GO:0015106 bicarbonate transmembrane transporter activity 2/1466 32/18639 0.0625 0.794636766712142 0.72894901019034 0.933097363889467 GO:0030515 snoRNA binding 2/1466 32/18639 0.0625 0.794636766712142 0.72894901019034 0.933097363889467 GO:0031369 translation initiation factor binding 2/1466 32/18639 0.0625 0.794636766712142 0.72894901019034 0.933097363889467 GO:0140142 nucleocytoplasmic carrier activity 2/1466 32/18639 0.0625 0.794636766712142 0.72894901019034 0.933097363889467 GO:0015179 L-amino acid transmembrane transporter activity 4/1466 62/18639 0.0645161290322581 0.82027021079963 0.72895921987709 0.933097363889467 GO:0004175 endopeptidase activity 29/1466 405/18639 0.0716049382716049 0.91039866606033 0.72924099386971 0.933097363889467 GO:0004866 endopeptidase inhibitor activity 11/1466 161/18639 0.0683229813664596 0.868671248082838 0.729448804898709 0.933097363889467 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0005521 lamin binding 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0008142 oxysterol binding 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0008391 arachidonate monooxygenase activity 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0030275 LRR domain binding 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0055102 lipase inhibitor activity 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0097027 ubiquitin-protein transferase activator activity 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1466 16/18639 0.0625 0.794636766712142 0.730512789325245 0.933097363889467 GO:0005342 organic acid transmembrane transporter activity 13/1466 189/18639 0.0687830687830688 0.874520886117066 0.732339849726821 0.933097363889467 GO:0004252 serine-type endopeptidase activity 12/1466 176/18639 0.0681818181818182 0.866876472776882 0.737832381231361 0.933097363889467 GO:0008188 neuropeptide receptor activity 3/1466 48/18639 0.0625 0.794636766712142 0.739291953166158 0.933097363889467 GO:0038187 pattern recognition receptor activity 3/1466 48/18639 0.0625 0.794636766712142 0.739291953166158 0.933097363889467 GO:0004676 3-phosphoinositide-dependent protein kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0004711 ribosomal protein S6 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0035175 histone H3S10 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0035979 histone H2AXS139 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0044022 histone H3S28 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0044023 histone H4S1 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0044024 histone H2AS1 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0044025 histone H2BS14 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0072354 histone H3T3 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0072371 histone H2AS121 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0072518 Rho-dependent protein serine/threonine kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0140823 histone H2BS36 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0140855 histone H3S57 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0140995 histone H2A kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0140997 histone H4 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0140998 histone H2B kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:1990244 histone H2AT120 kinase activity 17/1466 245/18639 0.0693877551020408 0.882208981819194 0.739897818319629 0.933097363889467 GO:0043178 alcohol binding 6/1466 92/18639 0.0652173913043478 0.8291861913518 0.739966450115508 0.933097363889467 GO:0022824 transmitter-gated monoatomic ion channel activity 4/1466 63/18639 0.0634920634920635 0.807250048723446 0.740494159734207 0.933097363889467 GO:0022835 transmitter-gated channel activity 4/1466 63/18639 0.0634920634920635 0.807250048723446 0.740494159734207 0.933097363889467 GO:0019199 transmembrane receptor protein kinase activity 5/1466 78/18639 0.0641025641025641 0.81501206842271 0.744318058825527 0.933097363889467 GO:0019239 deaminase activity 2/1466 33/18639 0.0606060606060606 0.770556864690562 0.744578685560982 0.933097363889467 GO:0071889 14-3-3 protein binding 2/1466 33/18639 0.0606060606060606 0.770556864690562 0.744578685560982 0.933097363889467 GO:0140311 protein sequestering activity 2/1466 33/18639 0.0606060606060606 0.770556864690562 0.744578685560982 0.933097363889467 GO:0004540 RNA nuclease activity 8/1466 121/18639 0.0661157024793388 0.84060748875334 0.744581270240299 0.933097363889467 GO:0004677 DNA-dependent protein kinase activity 17/1466 246/18639 0.0691056910569106 0.878622766445946 0.745792252908417 0.933097363889467 GO:0140857 histone H3T45 kinase activity 17/1466 246/18639 0.0691056910569106 0.878622766445946 0.745792252908417 0.933097363889467 GO:0015081 sodium ion transmembrane transporter activity 11/1466 164/18639 0.0670731707317073 0.852780920374006 0.751113848341646 0.933097363889467 GO:0035402 histone H3T11 kinase activity 17/1466 247/18639 0.0688259109311741 0.875065589253857 0.751600068197177 0.933097363889467 GO:0035403 histone H3T6 kinase activity 17/1466 247/18639 0.0688259109311741 0.875065589253857 0.751600068197177 0.933097363889467 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/1466 17/18639 0.0588235294117647 0.747893427493781 0.751726785504657 0.933097363889467 GO:0008484 sulfuric ester hydrolase activity 1/1466 17/18639 0.0588235294117647 0.747893427493781 0.751726785504657 0.933097363889467 GO:0016018 cyclosporin A binding 1/1466 17/18639 0.0588235294117647 0.747893427493781 0.751726785504657 0.933097363889467 GO:0030548 acetylcholine receptor regulator activity 1/1466 17/18639 0.0588235294117647 0.747893427493781 0.751726785504657 0.933097363889467 GO:0031489 myosin V binding 1/1466 17/18639 0.0588235294117647 0.747893427493781 0.751726785504657 0.933097363889467 GO:0032977 membrane insertase activity 1/1466 17/18639 0.0588235294117647 0.747893427493781 0.751726785504657 0.933097363889467 GO:1990226 histone methyltransferase binding 1/1466 17/18639 0.0588235294117647 0.747893427493781 0.751726785504657 0.933097363889467 GO:0001222 transcription corepressor binding 3/1466 49/18639 0.0612244897959184 0.778419689840466 0.751976211800003 0.933097363889467 GO:0004679 AMP-activated protein kinase activity 17/1466 248/18639 0.0685483870967742 0.871537098974607 0.757320899239389 0.934924092497447 GO:0016410 N-acyltransferase activity 6/1466 94/18639 0.0638297872340425 0.811543931961336 0.758449480495135 0.934924092497447 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/1466 34/18639 0.0588235294117647 0.747893427493781 0.759428546730962 0.934924092497447 GO:0016831 carboxy-lyase activity 2/1466 34/18639 0.0588235294117647 0.747893427493781 0.759428546730962 0.934924092497447 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/1466 34/18639 0.0588235294117647 0.747893427493781 0.759428546730962 0.934924092497447 GO:0160215 deacylase activity 4/1466 65/18639 0.0615384615384615 0.782411585685801 0.762438388693796 0.934924092497447 GO:0015605 organophosphate ester transmembrane transporter activity 3/1466 50/18639 0.06 0.762851296043656 0.764159519667962 0.934924092497447 GO:0008236 serine-type peptidase activity 13/1466 194/18639 0.0670103092783505 0.851981688021266 0.765084711385353 0.934924092497447 GO:0022836 gated channel activity 22/1466 318/18639 0.0691823899371069 0.87959793044866 0.76570662240548 0.934924092497447 GO:0004867 serine-type endopeptidase inhibitor activity 6/1466 95/18639 0.0631578947368421 0.80300136425648 0.767321563438444 0.934924092497447 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0003746 translation elongation factor activity 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0008525 phosphatidylcholine transporter activity 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0016854 racemase and epimerase activity 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0017075 syntaxin-1 binding 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0017128 phospholipid scramblase activity 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0022851 GABA-gated chloride ion channel activity 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0030228 lipoprotein particle receptor activity 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0034185 apolipoprotein binding 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0099602 neurotransmitter receptor regulator activity 1/1466 18/18639 0.0555555555555556 0.706343792633015 0.771271868334115 0.934924092497447 GO:0015101 organic cation transmembrane transporter activity 5/1466 81/18639 0.0617283950617284 0.784826436258905 0.773477885789939 0.936614354880997 GO:0003743 translation initiation factor activity 3/1466 51/18639 0.0588235294117647 0.747893427493781 0.775851656737525 0.938503995676209 GO:1902936 phosphatidylinositol bisphosphate binding 7/1466 111/18639 0.0630630630630631 0.801795656502341 0.77943158299059 0.941847169393865 GO:0008173 RNA methyltransferase activity 4/1466 67/18639 0.0597014925373134 0.759056015963837 0.782910614532668 0.944842586821264 GO:0030594 neurotransmitter receptor activity 6/1466 97/18639 0.0618556701030928 0.786444635096553 0.78433429208368 0.944842586821264 GO:0017171 serine hydrolase activity 13/1466 198/18639 0.0656565656565657 0.834769936748109 0.789232016364475 0.944842586821264 GO:0004890 GABA-A receptor activity 1/1466 19/18639 0.0526315789473684 0.669167803547067 0.789279249303032 0.944842586821264 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1466 19/18639 0.0526315789473684 0.669167803547067 0.789279249303032 0.944842586821264 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1466 19/18639 0.0526315789473684 0.669167803547067 0.789279249303032 0.944842586821264 GO:0046527 glucosyltransferase activity 1/1466 19/18639 0.0526315789473684 0.669167803547067 0.789279249303032 0.944842586821264 GO:0046624 sphingolipid transporter activity 1/1466 19/18639 0.0526315789473684 0.669167803547067 0.789279249303032 0.944842586821264 GO:0070003 threonine-type peptidase activity 1/1466 19/18639 0.0526315789473684 0.669167803547067 0.789279249303032 0.944842586821264 GO:0032934 sterol binding 4/1466 68/18639 0.0588235294117647 0.747893427493781 0.79260792511087 0.945997054002153 GO:1990841 promoter-specific chromatin binding 4/1466 68/18639 0.0588235294117647 0.747893427493781 0.79260792511087 0.945997054002153 GO:0008514 organic anion transmembrane transporter activity 18/1466 269/18639 0.0669144981412639 0.850763527186233 0.795411281992332 0.945997054002153 GO:0001664 G protein-coupled receptor binding 20/1466 297/18639 0.0673400673400673 0.856174294100624 0.796806751177957 0.945997054002153 GO:0140296 general transcription initiation factor binding 3/1466 53/18639 0.0566037735849057 0.719671034003449 0.79780546114282 0.945997054002153 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 3/1466 53/18639 0.0566037735849057 0.719671034003449 0.79780546114282 0.945997054002153 GO:0022829 wide pore channel activity 2/1466 37/18639 0.0540540540540541 0.68725341985915 0.799561605020145 0.945997054002153 GO:0004527 exonuclease activity 5/1466 84/18639 0.0595238095238095 0.75679692067823 0.800021847959018 0.945997054002153 GO:0046873 metal ion transmembrane transporter activity 31/1466 450/18639 0.0688888888888889 0.875866302864939 0.805637301977386 0.945997054002153 GO:0001614 purinergic nucleotide receptor activity 1/1466 20/18639 0.05 0.635709413369714 0.805869830426649 0.945997054002153 GO:0015464 acetylcholine receptor activity 1/1466 20/18639 0.05 0.635709413369714 0.805869830426649 0.945997054002153 GO:0016502 nucleotide receptor activity 1/1466 20/18639 0.05 0.635709413369714 0.805869830426649 0.945997054002153 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1466 20/18639 0.05 0.635709413369714 0.805869830426649 0.945997054002153 GO:0030742 GTP-dependent protein binding 1/1466 20/18639 0.05 0.635709413369714 0.805869830426649 0.945997054002153 GO:0042288 MHC class I protein binding 1/1466 20/18639 0.05 0.635709413369714 0.805869830426649 0.945997054002153 GO:0043024 ribosomal small subunit binding 1/1466 20/18639 0.05 0.635709413369714 0.805869830426649 0.945997054002153 GO:0061608 nuclear import signal receptor activity 1/1466 20/18639 0.05 0.635709413369714 0.805869830426649 0.945997054002153 GO:0140939 histone H4 methyltransferase activity 1/1466 20/18639 0.05 0.635709413369714 0.805869830426649 0.945997054002153 GO:0043130 ubiquitin binding 6/1466 100/18639 0.06 0.762851296043656 0.808057189415548 0.945997054002153 GO:0003925 G protein activity 3/1466 54/18639 0.0555555555555556 0.706343792633015 0.80809023596022 0.945997054002153 GO:0015485 cholesterol binding 3/1466 54/18639 0.0555555555555556 0.706343792633015 0.80809023596022 0.945997054002153 GO:0016278 lysine N-methyltransferase activity 4/1466 70/18639 0.0571428571428571 0.726525043851101 0.810955935498529 0.945997054002153 GO:0016782 transferase activity, transferring sulphur-containing groups 4/1466 70/18639 0.0571428571428571 0.726525043851101 0.810955935498529 0.945997054002153 GO:0000146 microfilament motor activity 2/1466 38/18639 0.0526315789473684 0.669167803547067 0.811557264698554 0.945997054002153 GO:0042162 telomeric DNA binding 2/1466 38/18639 0.0526315789473684 0.669167803547067 0.811557264698554 0.945997054002153 GO:0042887 amide transmembrane transporter activity 2/1466 38/18639 0.0526315789473684 0.669167803547067 0.811557264698554 0.945997054002153 GO:0046943 carboxylic acid transmembrane transporter activity 12/1466 188/18639 0.0638297872340425 0.811543931961336 0.812855476890686 0.946554208205703 GO:0015079 potassium ion transmembrane transporter activity 10/1466 160/18639 0.0625 0.794636766712142 0.816995935058097 0.946666219666246 GO:0005262 calcium channel activity 8/1466 131/18639 0.0610687022900763 0.776438978161482 0.817839707461531 0.946666219666246 GO:0140313 molecular sequestering activity 3/1466 55/18639 0.0545454545454545 0.693501178221506 0.817929828868966 0.946666219666246 GO:0015293 symporter activity 9/1466 146/18639 0.0616438356164384 0.783751331551702 0.820111591727653 0.946666219666246 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1466 21/18639 0.0476190476190476 0.605437536542584 0.821155013765955 0.946666219666246 GO:0001846 opsonin binding 1/1466 21/18639 0.0476190476190476 0.605437536542584 0.821155013765955 0.946666219666246 GO:0005123 death receptor binding 1/1466 21/18639 0.0476190476190476 0.605437536542584 0.821155013765955 0.946666219666246 GO:0008373 sialyltransferase activity 1/1466 21/18639 0.0476190476190476 0.605437536542584 0.821155013765955 0.946666219666246 GO:0009975 cyclase activity 1/1466 21/18639 0.0476190476190476 0.605437536542584 0.821155013765955 0.946666219666246 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1466 21/18639 0.0476190476190476 0.605437536542584 0.821155013765955 0.946666219666246 GO:0008238 exopeptidase activity 6/1466 102/18639 0.0588235294117647 0.747893427493781 0.822706909008233 0.947508755484531 GO:0015085 calcium ion transmembrane transporter activity 9/1466 147/18639 0.0612244897959184 0.778419689840466 0.826091708310137 0.950458456021833 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 3/1466 56/18639 0.0535714285714286 0.681117228610407 0.827336888157626 0.950942996946117 GO:0050997 quaternary ammonium group binding 2/1466 40/18639 0.05 0.635709413369714 0.833639524607053 0.956100454334991 GO:0071855 neuropeptide receptor binding 2/1466 40/18639 0.05 0.635709413369714 0.833639524607053 0.956100454334991 GO:0005243 gap junction channel activity 1/1466 22/18639 0.0454545454545455 0.577917648517921 0.835237447422583 0.956100454334991 GO:0033691 sialic acid binding 1/1466 22/18639 0.0454545454545455 0.577917648517921 0.835237447422583 0.956100454334991 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 4/1466 73/18639 0.0547945205479452 0.696667850268179 0.835966515098792 0.956100454334991 GO:0003727 single-stranded RNA binding 5/1466 89/18639 0.0561797752808989 0.714280239741251 0.838731170389041 0.958312644187083 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/1466 41/18639 0.0487804878048781 0.62020430572655 0.843780317917111 0.961226541832523 GO:0042287 MHC protein binding 2/1466 41/18639 0.0487804878048781 0.62020430572655 0.843780317917111 0.961226541832523 GO:0140318 protein transporter activity 2/1466 41/18639 0.0487804878048781 0.62020430572655 0.843780317917111 0.961226541832523 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1466 23/18639 0.0434782608695652 0.552790794234533 0.848211712990531 0.961528798419522 GO:0005158 insulin receptor binding 1/1466 23/18639 0.0434782608695652 0.552790794234533 0.848211712990531 0.961528798419522 GO:0005283 amino acid:sodium symporter activity 1/1466 23/18639 0.0434782608695652 0.552790794234533 0.848211712990531 0.961528798419522 GO:0016917 GABA receptor activity 1/1466 23/18639 0.0434782608695652 0.552790794234533 0.848211712990531 0.961528798419522 GO:0070577 lysine-acetylated histone binding 1/1466 23/18639 0.0434782608695652 0.552790794234533 0.848211712990531 0.961528798419522 GO:0044183 protein folding chaperone 4/1466 75/18639 0.0533333333333333 0.678090040927694 0.851054594264732 0.963137711124648 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 5/1466 91/18639 0.0549450549450549 0.698581772933751 0.8523917511661 0.963137711124648 GO:0036002 pre-mRNA binding 3/1466 59/18639 0.0508474576271186 0.646484149189539 0.853092884063941 0.963137711124648 GO:0070063 RNA polymerase binding 3/1466 59/18639 0.0508474576271186 0.646484149189539 0.853092884063941 0.963137711124648 GO:0008528 G protein-coupled peptide receptor activity 7/1466 122/18639 0.0573770491803279 0.729502605506229 0.853804054142561 0.963137711124648 GO:0004806 triacylglycerol lipase activity 1/1466 24/18639 0.0416666666666667 0.529757844474761 0.86016495905606 0.966419407544382 GO:0005315 phosphate transmembrane transporter activity 1/1466 24/18639 0.0416666666666667 0.529757844474761 0.86016495905606 0.966419407544382 GO:0048027 mRNA 5'-UTR binding 1/1466 24/18639 0.0416666666666667 0.529757844474761 0.86016495905606 0.966419407544382 GO:0140033 acetylation-dependent protein binding 1/1466 24/18639 0.0416666666666667 0.529757844474761 0.86016495905606 0.966419407544382 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1466 60/18639 0.05 0.635709413369714 0.860900477431217 0.966419407544382 GO:0005267 potassium channel activity 7/1466 124/18639 0.0564516129032258 0.717736434449677 0.864864208110579 0.967709332460256 GO:0051219 phosphoprotein binding 5/1466 93/18639 0.0537634408602151 0.683558508999692 0.865075787588399 0.967709332460256 GO:0008237 metallopeptidase activity 11/1466 184/18639 0.0597826086956522 0.760087342072484 0.865200218167405 0.967709332460256 GO:1901981 phosphatidylinositol phosphate binding 11/1466 185/18639 0.0594594594594595 0.755978761845065 0.869590426055258 0.967709332460256 GO:0001848 complement binding 1/1466 25/18639 0.04 0.508567530695771 0.871177484977296 0.967709332460256 GO:0004709 MAP kinase kinase kinase activity 1/1466 25/18639 0.04 0.508567530695771 0.871177484977296 0.967709332460256 GO:0005251 delayed rectifier potassium channel activity 1/1466 25/18639 0.04 0.508567530695771 0.871177484977296 0.967709332460256 GO:0008139 nuclear localization sequence binding 1/1466 25/18639 0.04 0.508567530695771 0.871177484977296 0.967709332460256 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1466 25/18639 0.04 0.508567530695771 0.871177484977296 0.967709332460256 GO:0004222 metalloendopeptidase activity 6/1466 110/18639 0.0545454545454545 0.693501178221506 0.872596346328512 0.967709332460256 GO:0008276 protein methyltransferase activity 5/1466 95/18639 0.0526315789473684 0.669167803547067 0.876829611011125 0.967709332460256 GO:0015370 solute:sodium symporter activity 4/1466 79/18639 0.0506329113924051 0.64375636796933 0.877717223885985 0.967709332460256 GO:0008234 cysteine-type peptidase activity 11/1466 187/18639 0.0588235294117647 0.747893427493781 0.878027393398713 0.967709332460256 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/1466 45/18639 0.0444444444444444 0.565075034106412 0.878953674955308 0.967709332460256 GO:0005160 transforming growth factor beta receptor binding 1/1466 26/18639 0.0384615384615385 0.489007241053626 0.88132327884338 0.967709332460256 GO:0008143 poly(A) binding 1/1466 26/18639 0.0384615384615385 0.489007241053626 0.88132327884338 0.967709332460256 GO:0008157 protein phosphatase 1 binding 1/1466 26/18639 0.0384615384615385 0.489007241053626 0.88132327884338 0.967709332460256 GO:0030507 spectrin binding 1/1466 26/18639 0.0384615384615385 0.489007241053626 0.88132327884338 0.967709332460256 GO:0051139 metal cation:proton antiporter activity 1/1466 26/18639 0.0384615384615385 0.489007241053626 0.88132327884338 0.967709332460256 GO:0070006 metalloaminopeptidase activity 1/1466 26/18639 0.0384615384615385 0.489007241053626 0.88132327884338 0.967709332460256 GO:0070412 R-SMAD binding 1/1466 26/18639 0.0384615384615385 0.489007241053626 0.88132327884338 0.967709332460256 GO:0120014 phospholipid transfer activity 1/1466 26/18639 0.0384615384615385 0.489007241053626 0.88132327884338 0.967709332460256 GO:0005244 voltage-gated monoatomic ion channel activity 10/1466 173/18639 0.0578034682080925 0.734924177306027 0.881850170986369 0.967709332460256 GO:1901682 sulfur compound transmembrane transporter activity 3/1466 63/18639 0.0476190476190476 0.605437536542584 0.882175232017495 0.967709332460256 GO:0001653 peptide receptor activity 7/1466 128/18639 0.0546875 0.695307170873124 0.884925709072959 0.967828410773279 GO:0003823 antigen binding 10/1466 174/18639 0.0574712643678161 0.730700475137602 0.885949090364013 0.967828410773279 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1466 46/18639 0.0434782608695652 0.552790794234533 0.886524916355881 0.967828410773279 GO:0035591 signaling adaptor activity 7/1466 129/18639 0.0542635658914729 0.68991719280434 0.88953273371203 0.967828410773279 GO:0019902 phosphatase binding 11/1466 190/18639 0.0578947368421053 0.736084583901773 0.889850528686139 0.967828410773279 GO:0022832 voltage-gated channel activity 10/1466 175/18639 0.0571428571428571 0.726525043851101 0.889930750155039 0.967828410773279 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1466 27/18639 0.037037037037037 0.470895861755343 0.890670513207298 0.967828410773279 GO:0015252 proton channel activity 1/1466 27/18639 0.037037037037037 0.470895861755343 0.890670513207298 0.967828410773279 GO:0016405 CoA-ligase activity 1/1466 27/18639 0.037037037037037 0.470895861755343 0.890670513207298 0.967828410773279 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1466 27/18639 0.037037037037037 0.470895861755343 0.890670513207298 0.967828410773279 GO:0140938 histone H3 methyltransferase activity 2/1466 47/18639 0.0425531914893617 0.541029287974224 0.893655005363954 0.970157926801508 GO:0120013 lipid transfer activity 3/1466 65/18639 0.0461538461538462 0.586808689264351 0.894698699293356 0.970378100549373 GO:0005242 inward rectifier potassium channel activity 1/1466 28/18639 0.0357142857142857 0.454078152406938 0.899282001904811 0.971696095691153 GO:0051537 2 iron, 2 sulfur cluster binding 1/1466 28/18639 0.0357142857142857 0.454078152406938 0.899282001904811 0.971696095691153 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/1466 28/18639 0.0357142857142857 0.454078152406938 0.899282001904811 0.971696095691153 GO:0097718 disordered domain specific binding 1/1466 28/18639 0.0357142857142857 0.454078152406938 0.899282001904811 0.971696095691153 GO:0005179 hormone activity 7/1466 132/18639 0.053030303030303 0.674237256604242 0.902431747683823 0.973880560923974 GO:0005543 phospholipid binding 32/1466 497/18639 0.0643863179074447 0.818619767719551 0.902991507962437 0.973880560923974 GO:0042054 histone methyltransferase activity 3/1466 67/18639 0.0447761194029851 0.569292011972878 0.906012769049666 0.975700677211625 GO:0060590 ATPase regulator activity 2/1466 49/18639 0.0408163265306122 0.518946459893644 0.906680920314587 0.975700677211625 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/1466 29/18639 0.0344827586206897 0.438420285082561 0.907215621012196 0.975700677211625 GO:0140098 catalytic activity, acting on RNA 24/1466 387/18639 0.062015503875969 0.788476791776389 0.910999984689251 0.976246235873577 GO:0140223 general transcription initiation factor activity 3/1466 68/18639 0.0441176470588235 0.560920070620335 0.911246838769918 0.976246235873577 GO:0048020 CCR chemokine receptor binding 2/1466 50/18639 0.04 0.508567530695771 0.912619312008196 0.976246235873577 GO:0051721 protein phosphatase 2A binding 1/1466 30/18639 0.0333333333333333 0.423806275579809 0.914524696756211 0.976246235873577 GO:0016279 protein-lysine N-methyltransferase activity 3/1466 69/18639 0.0434782608695652 0.552790794234533 0.916214688288177 0.976246235873577 GO:0098960 postsynaptic neurotransmitter receptor activity 3/1466 69/18639 0.0434782608695652 0.552790794234533 0.916214688288177 0.976246235873577 GO:0016779 nucleotidyltransferase activity 7/1466 136/18639 0.0514705882352941 0.654406749057058 0.917615931674346 0.976246235873577 GO:0032182 ubiquitin-like protein binding 6/1466 120/18639 0.05 0.635709413369714 0.917913597208416 0.976246235873577 GO:0016830 carbon-carbon lyase activity 2/1466 51/18639 0.0392156862745098 0.498595618329187 0.91820166528455 0.976246235873577 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 13/1466 229/18639 0.0567685589519651 0.721766146183954 0.918845149000382 0.976246235873577 GO:0005184 neuropeptide hormone activity 1/1466 31/18639 0.032258064516129 0.410135105399815 0.921258362969086 0.976246235873577 GO:0005452 solute:inorganic anion antiporter activity 1/1466 31/18639 0.032258064516129 0.410135105399815 0.921258362969086 0.976246235873577 GO:0016878 acid-thiol ligase activity 1/1466 31/18639 0.032258064516129 0.410135105399815 0.921258362969086 0.976246235873577 GO:0047499 calcium-independent phospholipase A2 activity 1/1466 31/18639 0.032258064516129 0.410135105399815 0.921258362969086 0.976246235873577 GO:0070273 phosphatidylinositol-4-phosphate binding 1/1466 31/18639 0.032258064516129 0.410135105399815 0.921258362969086 0.976246235873577 GO:0072349 modified amino acid transmembrane transporter activity 1/1466 31/18639 0.032258064516129 0.410135105399815 0.921258362969086 0.976246235873577 GO:0008013 beta-catenin binding 5/1466 106/18639 0.0471698113207547 0.599725861669541 0.926974273186161 0.978328173319654 GO:0047498 calcium-dependent phospholipase A2 activity 1/1466 32/18639 0.03125 0.397318383356071 0.927461890478078 0.978328173319654 GO:0051059 NF-kappaB binding 1/1466 32/18639 0.03125 0.397318383356071 0.927461890478078 0.978328173319654 GO:0070717 poly-purine tract binding 1/1466 32/18639 0.03125 0.397318383356071 0.927461890478078 0.978328173319654 GO:0160041 neuropeptide activity 1/1466 32/18639 0.03125 0.397318383356071 0.927461890478078 0.978328173319654 GO:0008146 sulfotransferase activity 2/1466 53/18639 0.0377358490566038 0.479780689335633 0.928374330511805 0.978396326402395 GO:0008175 tRNA methyltransferase activity 1/1466 34/18639 0.0294117647058824 0.37394671374689 0.938442094992367 0.986908137331823 GO:0090482 vitamin transmembrane transporter activity 1/1466 34/18639 0.0294117647058824 0.37394671374689 0.938442094992367 0.986908137331823 GO:0022843 voltage-gated monoatomic cation channel activity 7/1466 143/18639 0.048951048951049 0.622372852250069 0.939299855470217 0.986908137331823 GO:0003725 double-stranded RNA binding 3/1466 75/18639 0.04 0.508567530695771 0.941050138573613 0.986908137331823 GO:0170055 lipid transmembrane transporter activity 2/1466 56/18639 0.0357142857142857 0.454078152406938 0.941417234762879 0.986908137331823 GO:0004623 phospholipase A2 activity 1/1466 35/18639 0.0285714285714286 0.363262521925551 0.943292613064992 0.986908137331823 GO:0005154 epidermal growth factor receptor binding 1/1466 35/18639 0.0285714285714286 0.363262521925551 0.943292613064992 0.986908137331823 GO:0005343 organic acid:sodium symporter activity 1/1466 35/18639 0.0285714285714286 0.363262521925551 0.943292613064992 0.986908137331823 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1466 36/18639 0.0277777777777778 0.353171896316508 0.947761169786488 0.989788588175211 GO:0016409 palmitoyltransferase activity 1/1466 36/18639 0.0277777777777778 0.353171896316508 0.947761169786488 0.989788588175211 GO:0016755 aminoacyltransferase activity 30/1466 496/18639 0.0604838709677419 0.769003322624653 0.950466540345127 0.990150015664032 GO:0030280 structural constituent of skin epidermis 1/1466 37/18639 0.027027027027027 0.343626709929575 0.951877824363331 0.990150015664032 GO:0045309 protein phosphorylated amino acid binding 2/1466 59/18639 0.0338983050847458 0.430989432793026 0.952181056716941 0.990150015664032 GO:0005126 cytokine receptor binding 15/1466 275/18639 0.0545454545454545 0.693501178221506 0.952440549191191 0.990150015664032 GO:0005249 voltage-gated potassium channel activity 4/1466 98/18639 0.0408163265306122 0.518946459893644 0.955173724769135 0.990150015664032 GO:0001098 basal transcription machinery binding 2/1466 60/18639 0.0333333333333333 0.423806275579809 0.955328662899207 0.990150015664032 GO:0001099 basal RNA polymerase II transcription machinery binding 2/1466 60/18639 0.0333333333333333 0.423806275579809 0.955328662899207 0.990150015664032 GO:0043531 ADP binding 1/1466 38/18639 0.0263157894736842 0.334583901773533 0.955670271921839 0.990150015664032 GO:0000049 tRNA binding 3/1466 80/18639 0.0375 0.476782060027285 0.956334676793658 0.990150015664032 GO:0016874 ligase activity 8/1466 167/18639 0.0479041916167665 0.609062911012899 0.956687406815768 0.990150015664032 GO:0015297 antiporter activity 6/1466 135/18639 0.0444444444444444 0.565075034106412 0.959539556455566 0.992212050313372 GO:0004177 aminopeptidase activity 1/1466 40/18639 0.025 0.317854706684857 0.962382606363888 0.992879860753669 GO:0140662 ATP-dependent protein folding chaperone 1/1466 40/18639 0.025 0.317854706684857 0.962382606363888 0.992879860753669 GO:0019787 ubiquitin-like protein transferase activity 28/1466 479/18639 0.058455114822547 0.743209335046011 0.964449170647669 0.992879860753669 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/1466 41/18639 0.024390243902439 0.310102152863275 0.965347663575057 0.992879860753669 GO:0017080 sodium channel regulator activity 1/1466 41/18639 0.024390243902439 0.310102152863275 0.965347663575057 0.992879860753669 GO:0140828 metal cation:monoatomic cation antiporter activity 1/1466 41/18639 0.024390243902439 0.310102152863275 0.965347663575057 0.992879860753669 GO:0043175 RNA polymerase core enzyme binding 1/1466 42/18639 0.0238095238095238 0.302718768271292 0.968079157563603 0.993907002121849 GO:0048487 beta-tubulin binding 1/1466 42/18639 0.0238095238095238 0.302718768271292 0.968079157563603 0.993907002121849 GO:0015291 secondary active transmembrane transporter activity 15/1466 287/18639 0.0522648083623693 0.664504613278446 0.968930136383952 0.993907002121849 GO:0005548 phospholipid transporter activity 2/1466 68/18639 0.0294117647058824 0.37394671374689 0.974264552843408 0.995517629267508 GO:0008009 chemokine activity 1/1466 45/18639 0.0222222222222222 0.282537517053206 0.975049007789618 0.995517629267508 GO:0140303 intramembrane lipid transporter activity 1/1466 45/18639 0.0222222222222222 0.282537517053206 0.975049007789618 0.995517629267508 GO:0004620 phospholipase activity 4/1466 109/18639 0.036697247706422 0.466575716234652 0.975942145318845 0.995517629267508 GO:0001784 phosphotyrosine residue binding 1/1466 47/18639 0.0212765957446809 0.270514643987112 0.978828409918381 0.995517629267508 GO:0043495 protein-membrane adaptor activity 1/1466 47/18639 0.0212765957446809 0.270514643987112 0.978828409918381 0.995517629267508 GO:0016298 lipase activity 5/1466 130/18639 0.0384615384615385 0.489007241053626 0.979000087352454 0.995517629267508 GO:0052689 carboxylic ester hydrolase activity 3/1466 92/18639 0.0326086956521739 0.4145930956759 0.979229553036743 0.995517629267508 GO:0005125 cytokine activity 11/1466 234/18639 0.047008547008547 0.59767551684332 0.979802488360018 0.995517629267508 GO:0032266 phosphatidylinositol-3-phosphate binding 1/1466 48/18639 0.0208333333333333 0.264878922237381 0.980497813482261 0.995517629267508 GO:0042379 chemokine receptor binding 2/1466 72/18639 0.0277777777777778 0.353171896316508 0.98054489431133 0.995517629267508 GO:0035091 phosphatidylinositol binding 14/1466 284/18639 0.0492957746478873 0.626755759660281 0.980852291574659 0.995517629267508 GO:0061630 ubiquitin protein ligase activity 18/1466 353/18639 0.0509915014164306 0.6483155490456 0.984432646047812 0.99743888699481 GO:0016597 amino acid binding 1/1466 51/18639 0.0196078431372549 0.249297809164594 0.984757338905281 0.99743888699481 GO:0004842 ubiquitin-protein transferase activity 24/1466 449/18639 0.0534521158129176 0.679600263735997 0.985873015772275 0.99743888699481 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/1466 53/18639 0.0188679245283019 0.239890344667816 0.987066905500929 0.99743888699481 GO:0017046 peptide hormone binding 1/1466 53/18639 0.0188679245283019 0.239890344667816 0.987066905500929 0.99743888699481 GO:0061980 regulatory RNA binding 1/1466 58/18639 0.0172413793103448 0.21921014254128 0.991424260584095 0.999999999999999 GO:0019783 ubiquitin-like protein peptidase activity 4/1466 127/18639 0.031496062992126 0.400446874563599 0.991739934125438 0.999999999999999 GO:0061659 ubiquitin-like protein ligase activity 18/1466 372/18639 0.0483870967741935 0.615202658099723 0.992382782192607 0.999999999999999 GO:0005319 lipid transporter activity 6/1466 178/18639 0.0337078651685393 0.428568143844751 0.995839821448056 0.999999999999999 GO:0140101 catalytic activity, acting on a tRNA 3/1466 139/18639 0.0215827338129496 0.274406941022898 0.999088682255835 0.999999999999999 GO:0030527 structural constituent of chromatin 1/1466 98/18639 0.0102040816326531 0.129736614973411 0.999680831163433 0.999999999999999 GO:0004843 cysteine-type deubiquitinase activity 1/1466 108/18639 0.00925925925925926 0.117723965438836 0.999859975014885 0.999999999999999 GO:0003730 mRNA 3'-UTR binding 7/1466 262/18639 0.0267175572519084 0.339692052945648 0.999902564625382 0.999999999999999 GO:0101005 deubiquitinase activity 1/1466 115/18639 0.00869565217391304 0.110558158846907 0.999921365106848 0.999999999999999 GO:0045182 translation regulator activity 6/1466 356/18639 0.0168539325842697 0.214284071922375 0.999999955717731 0.999999999999999 GO:0030371 translation repressor activity 3/1466 329/18639 0.00911854103343465 0.115934847423048 0.99999999932677 0.999999999999999 GO:0004984 olfactory receptor activity 1/1466 419/18639 0.00238663484486874 0.0303441247431844 0.999999999999999 0.999999999999999