category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Genetic Information Processing Translation hsa03010 Ribosome 2/4 222/9376 21.1171171171171 RPL27A/RPS20 6.26666200335838 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 2/4 238/9376 19.6974789915966 RPL27A/RPS20 6.03594744189612 Metabolism Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism 1/4 38/9376 61.6842105263158 NAPRT 7.74354923016772 Organismal Systems Excretory system hsa04960 Aldosterone-regulated sodium reabsorption 1/4 38/9376 61.6842105263158 IGF1 7.74354923016772 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 1/4 52/9376 45.0769230769231 IGF1 6.58432566096806 Organismal Systems Nervous system hsa04730 Long-term depression 1/4 60/9376 39.0666666666667 IGF1 6.11090072403869 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 1/4 62/9376 37.8064516129032 IGF1 6.00691065510361 Human Diseases Cancer: specific types hsa05218 Melanoma 1/4 73/9376 32.1095890410959 IGF1 5.51243761560839 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/4 75/9376 31.2533333333333 IGF1 5.43423650940973 Human Diseases Cancer: specific types hsa05214 Glioma 1/4 76/9376 30.8421052631579 IGF1 5.39627748539267 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/4 80/9376 29.3 IGF1 5.25149390051759 Organismal Systems Aging hsa04211 Longevity regulating pathway 1/4 90/9376 26.0444444444444 IGF1 4.93194030347257 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/4 99/9376 23.6767676767677 IGF1 4.68591561696917 Organismal Systems Sensory system hsa04750 Inflammatory mediator regulation of TRP channels 1/4 99/9376 23.6767676767677 IGF1 4.68591561696917 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 1/4 99/9376 23.6767676767677 IGF1 4.68591561696917 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 1/4 105/9376 22.3238095238095 IGF1 4.53937067172441 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/4 106/9376 22.1132075471698 IGF1 4.51613355099578 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 1/4 110/9376 21.3090909090909 IGF1 4.42629313607939 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/4 110/9376 21.3090909090909 IGF1 4.42629313607939 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/4 122/9376 19.2131147540984 IGF1 4.18310615252147 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/4 122/9376 19.2131147540984 IGF1 4.18310615252147 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/4 133/9376 17.6240601503759 IGF1 3.98892563119861 Cellular Processes Cell growth and death hsa04114 Oocyte meiosis 1/4 138/9376 16.9855072463768 IGF1 3.90819729537518 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 1/4 144/9376 16.2777777777778 IGF1 3.81674399318434 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/4 148/9376 15.8378378378378 IGF1 3.75878235149505 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/4 154/9376 15.2207792207792 NAPRT 3.67595925872214 NA NA hsa04518 Integrin signaling 1/4 154/9376 15.2207792207792 IGF1 3.67595925872214 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 1/4 158/9376 14.8354430379747 IGF1 3.62328716976344 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/4 201/9376 11.6616915422886 IGF1 3.15660761425043 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/4 203/9376 11.5467980295567 IGF1 3.13842999247056 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 1/4 204/9376 11.4901960784314 IGF1 3.12943662165627 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/4 212/9376 11.0566037735849 IGF1 3.05968152064884 NA NA hsa04081 Hormone signaling 1/4 219/9376 10.703196347032 IGF1 3.00164801467412 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/4 238/9376 9.84873949579832 IGF1 2.85656299160297 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/4 300/9376 7.81333333333333 IGF1 2.47783574874596 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/4 362/9376 6.47513812154696 IGF1 2.19477539053578