ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	26/453	68/18639	0.382352941176471	15.7321776392676	8.93440079493514e-25	6.42383417155836e-22
GO:0009055	electron transfer activity	30/453	116/18639	0.258620689655172	10.641128111441	1.10889776241544e-22	3.9864874558835e-20
GO:0003735	structural constituent of ribosome	33/453	175/18639	0.188571428571429	7.75890255439924	3.41379099188183e-20	8.18171907721013e-18
GO:0022853	active monoatomic ion transmembrane transporter activity	27/453	118/18639	0.228813559322034	9.4146930070715	4.98839941286241e-19	8.96664794462018e-17
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	19/453	58/18639	0.327586206896552	13.4787622744919	5.79282106725255e-17	8.33007669470916e-15
GO:0003954	NADH dehydrogenase activity	17/453	44/18639	0.386363636363636	15.8972004816376	1.0047965353803e-16	1.20408118156406e-14
GO:0008137	NADH dehydrogenase (ubiquinone) activity	16/453	41/18639	0.390243902439024	16.0568567275077	6.72977866018232e-16	6.9124440809587e-14
GO:0016651	oxidoreductase activity, acting on NAD(P)H	21/453	88/18639	0.238636363636364	9.81885912101144	1.761514547414e-15	1.58316119948833e-13
GO:0015399	primary active transmembrane transporter activity	27/453	166/18639	0.162650602409639	6.69237213755685	4.60656808864025e-15	3.68013606192482e-13
GO:0015078	proton transmembrane transporter activity	28/453	185/18639	0.151351351351351	6.22745659566852	9.47547245421539e-15	6.81286469458087e-13
GO:0016675	oxidoreductase activity, acting on a heme group of donors	8/453	16/18639	0.5	20.5728476821192	1.24206247988686e-09	8.1185720276241e-08
GO:0004129	cytochrome-c oxidase activity	7/453	15/18639	0.466666666666667	19.2013245033113	2.60057914728025e-08	1.55818033907875e-06
GO:0022804	active transmembrane transporter activity	30/453	457/18639	0.0656455142231947	2.70103033025635	9.12827711525876e-07	5.04863941990081e-05
GO:0016209	antioxidant activity	12/453	86/18639	0.13953488372093	5.74125981826582	1.10295296248777e-06	5.66445128591931e-05
GO:0043021	ribonucleoprotein complex binding	17/453	177/18639	0.096045197740113	3.95184644741273	1.57547712910394e-06	7.55178703883821e-05
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	5/453	15/18639	0.333333333333333	13.7152317880795	2.03643474603335e-05	0.000915122863998735
GO:0016853	isomerase activity	15/453	180/18639	0.0833333333333333	3.42880794701987	3.52592375689699e-05	0.00149125834188761
GO:0017069	snRNA binding	8/453	54/18639	0.148148148148148	6.09565857247976	4.46584554145276e-05	0.0017838571912803
GO:0004601	peroxidase activity	8/453	57/18639	0.140350877192982	5.77483443708609	6.65523314916308e-05	0.00251848033381487
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	8/453	59/18639	0.135593220338983	5.57907733752385	8.56042881029681e-05	0.00307747415730171
GO:0070990	snRNP binding	4/453	11/18639	0.363636363636364	14.9620710415412	9.92105602249574e-05	0.00339678060960688
GO:0016860	intramolecular oxidoreductase activity	7/453	53/18639	0.132075471698113	5.43433712357866	0.000280568346659508	0.00887730958506813
GO:0032036	myosin heavy chain binding	4/453	14/18639	0.285714285714286	11.755912961211	0.000283975132762958	0.00887730958506813
GO:0031386	protein tag activity	4/453	15/18639	0.266666666666667	10.9721854304636	0.00037983360014573	0.0109240143401912
GO:0141047	molecular tag activity	4/453	15/18639	0.266666666666667	10.9721854304636	0.00037983360014573	0.0109240143401912
GO:0043022	ribosome binding	10/453	112/18639	0.0892857142857143	3.67372280037843	0.000404348558107075	0.0111817928184226
GO:0005159	insulin-like growth factor receptor binding	4/453	16/18639	0.25	10.2864238410596	0.00049676790834227	0.012756290217789
GO:0017070	U6 snRNA binding	4/453	16/18639	0.25	10.2864238410596	0.00049676790834227	0.012756290217789
GO:0016918	retinal binding	4/453	19/18639	0.210526315789474	8.66225165562914	0.000998555025893656	0.0247572780557772
GO:0051287	NAD binding	6/453	54/18639	0.111111111111111	4.57174392935982	0.00191970500230164	0.0460089298884959
GO:0005501	retinoid binding	5/453	38/18639	0.131578947368421	5.41390728476821	0.00214902609142967	0.0482859299918103
GO:0019840	isoprenoid binding	5/453	38/18639	0.131578947368421	5.41390728476821	0.00214902609142967	0.0482859299918103
GO:0016504	peptidase activator activity	6/453	57/18639	0.105263157894737	4.33112582781457	0.00253769111397999	0.0552909063924732
GO:0031625	ubiquitin protein ligase binding	16/453	302/18639	0.0529801324503311	2.17990439015833	0.00307332336995059	0.0631956215091193
GO:0033293	monocarboxylic acid binding	7/453	79/18639	0.0886075949367089	3.64582110822366	0.0030762819927944	0.0631956215091193
GO:0120014	phospholipid transfer activity	4/453	26/18639	0.153846153846154	6.3301069791136	0.00336763583402795	0.0672591712407249
GO:0019205	nucleobase-containing compound kinase activity	5/453	44/18639	0.113636363636364	4.67564720048164	0.0041284566615897	0.0802259551265674
GO:0005504	fatty acid binding	5/453	47/18639	0.106382978723404	4.37720163449345	0.00549569245962361	0.10398428627551
GO:0044389	ubiquitin-like protein ligase binding	16/453	322/18639	0.0496894409937888	2.04450660194973	0.00567840311033578	0.104686457341831
GO:0019841	retinol binding	3/453	16/18639	0.1875	7.7148178807947	0.00630918258776495	0.113407557015075
GO:0071813	lipoprotein particle binding	4/453	32/18639	0.125	5.1432119205298	0.00722456459758719	0.119367896016898
GO:0071814	protein-lipid complex binding	4/453	32/18639	0.125	5.1432119205298	0.00722456459758719	0.119367896016898
GO:0004550	nucleoside diphosphate kinase activity	3/453	17/18639	0.176470588235294	7.26100506427737	0.00752460374864684	0.119367896016898
GO:0016018	cyclosporin A binding	3/453	17/18639	0.176470588235294	7.26100506427737	0.00752460374864684	0.119367896016898
GO:0030169	low-density lipoprotein particle binding	3/453	17/18639	0.176470588235294	7.26100506427737	0.00752460374864684	0.119367896016898
GO:0033218	amide binding	13/453	247/18639	0.0526315789473684	2.16556291390728	0.00763688903585159	0.119367896016898
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	4/453	34/18639	0.117647058823529	4.84067004285158	0.0089697572188193	0.137218200858108
GO:0061134	peptidase regulator activity	12/453	226/18639	0.0530973451327434	2.18472718748169	0.00950820068303774	0.142424922731336
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	8/453	122/18639	0.0655737704918033	2.69807838454022	0.0099139240784486	0.145471661477644
GO:0097001	ceramide binding	3/453	19/18639	0.157894736842105	6.49668874172185	0.0103444642488977	0.148753395899149
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	4/453	36/18639	0.111111111111111	4.57174392935982	0.0109689509193925	0.148805202095155
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	4/453	36/18639	0.111111111111111	4.57174392935982	0.0109689509193925	0.148805202095155
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	4/453	36/18639	0.111111111111111	4.57174392935982	0.0109689509193925	0.148805202095155
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/453	20/18639	0.15	6.17185430463576	0.0119538833167752	0.156269856450207
GO:0016505	peptidase activator activity involved in apoptotic process	3/453	20/18639	0.15	6.17185430463576	0.0119538833167752	0.156269856450207
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4/453	39/18639	0.102564102564103	4.22007131940907	0.014471031167831	0.185797703744115
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	8/453	132/18639	0.0606060606060606	2.49367850692354	0.0154127304579795	0.1867123165305
GO:0031683	G-protein beta/gamma-subunit complex binding	3/453	22/18639	0.136363636363636	5.61077664057796	0.015580999988637	0.1867123165305
GO:0034062	5'-3' RNA polymerase activity	3/453	22/18639	0.136363636363636	5.61077664057796	0.015580999988637	0.1867123165305
GO:0097747	RNA polymerase activity	3/453	22/18639	0.136363636363636	5.61077664057796	0.015580999988637	0.1867123165305
GO:0045296	cadherin binding	15/453	334/18639	0.0449101796407186	1.84786057025023	0.0170978734782632	0.198965739645468
GO:0061650	ubiquitin-like protein conjugating enzyme activity	4/453	41/18639	0.0975609756097561	4.01421418187692	0.0171569900667858	0.198965739645468
GO:0004602	glutathione peroxidase activity	3/453	23/18639	0.130434782608696	5.36682983011805	0.0176012601395039	0.200877873655608
GO:0016859	cis-trans isomerase activity	4/453	42/18639	0.0952380952380952	3.91863765373699	0.0186088450199912	0.209058743271463
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/453	24/18639	0.125	5.1432119205298	0.0197604397896638	0.216071643690208
GO:0008200	ion channel inhibitor activity	4/453	43/18639	0.0930232558139535	3.82750654551055	0.0201346316095187	0.216071643690208
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/453	43/18639	0.0930232558139535	3.82750654551055	0.0201346316095187	0.216071643690208
GO:0019843	rRNA binding	5/453	65/18639	0.0769230769230769	3.1650534895568	0.0207901874516406	0.216639779387385
GO:0120013	lipid transfer activity	5/453	65/18639	0.0769230769230769	3.1650534895568	0.0207901874516406	0.216639779387385
GO:0016248	channel inhibitor activity	4/453	44/18639	0.0909090909090909	3.74051776038531	0.0217352491043116	0.218608756787514
GO:0001094	TFIID-class transcription factor complex binding	2/453	10/18639	0.2	8.22913907284768	0.0233089450972771	0.218608756787514
GO:0004090	carbonyl reductase (NADPH) activity	2/453	10/18639	0.2	8.22913907284768	0.0233089450972771	0.218608756787514
GO:0016783	sulfurtransferase activity	2/453	10/18639	0.2	8.22913907284768	0.0233089450972771	0.218608756787514
GO:0016868	intramolecular phosphotransferase activity	2/453	10/18639	0.2	8.22913907284768	0.0233089450972771	0.218608756787514
GO:0033204	ribonuclease P RNA binding	2/453	10/18639	0.2	8.22913907284768	0.0233089450972771	0.218608756787514
GO:0043295	glutathione binding	2/453	10/18639	0.2	8.22913907284768	0.0233089450972771	0.218608756787514
GO:0141110	transporter inhibitor activity	4/453	45/18639	0.0888888888888889	3.65739514348786	0.0234115080287045	0.218608756787514
GO:0097602	cullin family protein binding	3/453	26/18639	0.115384615384615	4.7475802343352	0.0244969670260005	0.224545293647016
GO:0005548	phospholipid transporter activity	5/453	68/18639	0.0735294117647059	3.02541877678224	0.0247491826341755	0.224545293647016
GO:0008201	heparin binding	9/453	172/18639	0.0523255813953488	2.15297243184968	0.0249841773181658	0.224545293647016
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/453	11/18639	0.181818181818182	7.48103552077062	0.0280365866852484	0.237156539137572
GO:0010854	adenylate cyclase regulator activity	2/453	11/18639	0.181818181818182	7.48103552077062	0.0280365866852484	0.237156539137572
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/453	11/18639	0.181818181818182	7.48103552077062	0.0280365866852484	0.237156539137572
GO:0019206	nucleoside kinase activity	2/453	11/18639	0.181818181818182	7.48103552077062	0.0280365866852484	0.237156539137572
GO:1900750	oligopeptide binding	2/453	11/18639	0.181818181818182	7.48103552077062	0.0280365866852484	0.237156539137572
GO:0016866	intramolecular transferase activity	3/453	28/18639	0.107142857142857	4.40846736045412	0.0297904764108474	0.246199454475854
GO:0046625	sphingolipid binding	3/453	28/18639	0.107142857142857	4.40846736045412	0.0297904764108474	0.246199454475854
GO:0005518	collagen binding	5/453	72/18639	0.0694444444444444	2.85733995584989	0.0307367279404821	0.251133038513711
GO:0004526	ribonuclease P activity	2/453	12/18639	0.166666666666667	6.85761589403973	0.0331110861086439	0.261613966067197
GO:0010853	cyclase activator activity	2/453	12/18639	0.166666666666667	6.85761589403973	0.0331110861086439	0.261613966067197
GO:0016208	AMP binding	2/453	12/18639	0.166666666666667	6.85761589403973	0.0331110861086439	0.261613966067197
GO:0031210	phosphatidylcholine binding	3/453	30/18639	0.1	4.11456953642384	0.035636596682216	0.278507750157753
GO:1901681	sulfur compound binding	12/453	275/18639	0.0436363636363636	1.79544852498495	0.0371995142258798	0.287596244391479
GO:0019855	calcium channel inhibitor activity	2/453	13/18639	0.153846153846154	6.3301069791136	0.0385128695326844	0.294582480787235
GO:0030332	cyclin binding	3/453	34/18639	0.0882352941176471	3.63050253213868	0.0489511060265254	0.370482581400755
GO:0055106	ubiquitin-protein transferase regulator activity	3/453	36/18639	0.0833333333333333	3.42880794701987	0.0563941299293013	0.414504844138359
GO:0034450	ubiquitin-ubiquitin ligase activity	2/453	16/18639	0.125	5.1432119205298	0.0564971832066192	0.414504844138359
GO:0097027	ubiquitin-protein transferase activator activity	2/453	16/18639	0.125	5.1432119205298	0.0564971832066192	0.414504844138359
GO:0022829	wide pore channel activity	3/453	37/18639	0.0810810810810811	3.33613746196528	0.0603052793386322	0.432987403336005
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/453	17/18639	0.117647058823529	4.84067004285158	0.0630268604676822	0.432987403336005
GO:0004549	tRNA-specific ribonuclease activity	2/453	17/18639	0.117647058823529	4.84067004285158	0.0630268604676822	0.432987403336005
GO:0008429	phosphatidylethanolamine binding	2/453	17/18639	0.117647058823529	4.84067004285158	0.0630268604676822	0.432987403336005
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/453	17/18639	0.117647058823529	4.84067004285158	0.0630268604676822	0.432987403336005
GO:0051787	misfolded protein binding	2/453	17/18639	0.117647058823529	4.84067004285158	0.0630268604676822	0.432987403336005
GO:0004197	cysteine-type endopeptidase activity	5/453	88/18639	0.0568181818181818	2.33782360024082	0.0632318182896809	0.432987403336005
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/453	39/18639	0.0769230769230769	3.1650534895568	0.0684956412938451	0.448069364880808
GO:0003746	translation elongation factor activity	2/453	18/18639	0.111111111111111	4.57174392935982	0.0697966187296947	0.448069364880808
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/453	18/18639	0.111111111111111	4.57174392935982	0.0697966187296947	0.448069364880808
GO:0008308	voltage-gated monoatomic anion channel activity	2/453	18/18639	0.111111111111111	4.57174392935982	0.0697966187296947	0.448069364880808
GO:0031690	adrenergic receptor binding	2/453	18/18639	0.111111111111111	4.57174392935982	0.0697966187296947	0.448069364880808
GO:0070628	proteasome binding	2/453	18/18639	0.111111111111111	4.57174392935982	0.0697966187296947	0.448069364880808
GO:1901611	phosphatidylglycerol binding	2/453	18/18639	0.111111111111111	4.57174392935982	0.0697966187296947	0.448069364880808
GO:0005539	glycosaminoglycan binding	10/453	242/18639	0.0413223140495868	1.70023534562969	0.0722196803549951	0.449817035791163
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3/453	40/18639	0.075	3.08592715231788	0.0727700383025075	0.449817035791163
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	3/453	40/18639	0.075	3.08592715231788	0.0727700383025075	0.449817035791163
GO:0050997	quaternary ammonium group binding	3/453	40/18639	0.075	3.08592715231788	0.0727700383025075	0.449817035791163
GO:0052689	carboxylic ester hydrolase activity	5/453	92/18639	0.0543478260869565	2.23617909588252	0.0735330394230134	0.449817035791163
GO:0019842	vitamin binding	7/453	150/18639	0.0466666666666667	1.92013245033113	0.0738225455123189	0.449817035791163
GO:0046624	sphingolipid transporter activity	2/453	19/18639	0.105263157894737	4.33112582781457	0.0767909898450826	0.458499419648883
GO:0070003	threonine-type peptidase activity	2/453	19/18639	0.105263157894737	4.33112582781457	0.0767909898450826	0.458499419648883
GO:0140318	protein transporter activity	3/453	41/18639	0.0731707317073171	3.01066063640769	0.0771605421105908	0.458499419648883
GO:0046906	tetrapyrrole binding	7/453	152/18639	0.0460526315789474	1.89486754966887	0.0779783357260022	0.45956084743439
GO:0008307	structural constituent of muscle	3/453	42/18639	0.0714285714285714	2.93897824030274	0.0816645188098677	0.477372268490202
GO:0001972	retinoic acid binding	2/453	20/18639	0.1	4.11456953642384	0.0839951127926724	0.483139888783451
GO:0010851	cyclase regulator activity	2/453	20/18639	0.1	4.11456953642384	0.0839951127926724	0.483139888783451
GO:0048156	tau protein binding	3/453	43/18639	0.0697674418604651	2.87062990913291	0.0862792603498939	0.49099650711144
GO:0031406	carboxylic acid binding	8/453	187/18639	0.0427807486631016	1.76024365194603	0.0867267822018815	0.49099650711144
GO:0043177	organic acid binding	8/453	189/18639	0.0423280423280423	1.74161673499422	0.0908486260654814	0.509401542188354
GO:0051428	peptide hormone receptor binding	2/453	21/18639	0.0952380952380952	3.91863765373699	0.091394713410706	0.509401542188354
GO:0005178	integrin binding	7/453	161/18639	0.0434782608695652	1.78894327670602	0.0983282319395985	0.539119734373821
GO:0061133	endopeptidase activator activity	2/453	22/18639	0.0909090909090909	3.74051776038531	0.0989760847529128	0.539119734373821
GO:0070034	telomerase RNA binding	2/453	22/18639	0.0909090909090909	3.74051776038531	0.0989760847529128	0.539119734373821
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3/453	46/18639	0.0652173913043478	2.68341491505903	0.100760053522495	0.544710364531385
GO:0004521	RNA endonuclease activity	4/453	73/18639	0.0547945205479452	2.25455865009526	0.101811497029607	0.546287062420055
GO:0005179	hormone activity	6/453	132/18639	0.0454545454545455	1.87025888019266	0.103064607399678	0.548914464595323
GO:0005158	insulin receptor binding	2/453	23/18639	0.0869565217391304	3.57788655341204	0.106726068049428	0.564235609761314
GO:0051087	protein-folding chaperone binding	6/453	134/18639	0.0447761194029851	1.84234456854799	0.108694850358463	0.57037027687259
GO:0000287	magnesium ion binding	9/453	230/18639	0.0391304347826087	1.61004894903542	0.109473015588898	0.57037027687259
GO:0017022	myosin binding	4/453	76/18639	0.0526315789473684	2.16556291390728	0.113625850647462	0.587748105147664
GO:0048027	mRNA 5'-UTR binding	2/453	24/18639	0.0833333333333333	3.42880794701987	0.114632034254861	0.58871737592318
GO:0051540	metal cluster binding	4/453	77/18639	0.051948051948052	2.13743872022018	0.117692932630236	0.600150486249216
GO:0017025	TBP-class protein binding	2/453	25/18639	0.08	3.29165562913907	0.12268186616632	0.616840991423667
GO:0120020	cholesterol transfer activity	2/453	25/18639	0.08	3.29165562913907	0.12268186616632	0.616840991423667
GO:0016835	carbon-oxygen lyase activity	4/453	79/18639	0.0506329113924051	2.08332634755638	0.12601341527226	0.629191983199689
GO:0000049	tRNA binding	4/453	80/18639	0.05	2.05728476821192	0.1302643446197	0.644460093473118
GO:0050750	low-density lipoprotein particle receptor binding	2/453	26/18639	0.0769230769230769	3.1650534895568	0.13086394109468	0.644460093473118
GO:0005080	protein kinase C binding	3/453	52/18639	0.0576923076923077	2.3737901171676	0.132322840636977	0.644860271887921
GO:0020037	heme binding	6/453	142/18639	0.0422535211267606	1.7385505083481	0.132738971125747	0.644860271887921
GO:0140296	general transcription initiation factor binding	3/453	53/18639	0.0566037735849057	2.32900162439085	0.137885409163192	0.662656655750895
GO:0004364	glutathione transferase activity	2/453	27/18639	0.0740740740740741	3.04782928623988	0.139167114072858	0.662656655750895
GO:0008320	protein transmembrane transporter activity	2/453	27/18639	0.0740740740740741	3.04782928623988	0.139167114072858	0.662656655750895
GO:0051393	alpha-actinin binding	2/453	28/18639	0.0714285714285714	2.93897824030274	0.147580701585321	0.690252740190239
GO:0051537	2 iron, 2 sulfur cluster binding	2/453	28/18639	0.0714285714285714	2.93897824030274	0.147580701585321	0.690252740190239
GO:0051117	ATPase binding	4/453	84/18639	0.0476190476190476	1.9593188268685	0.1478427287751	0.690252740190239
GO:0051861	glycolipid binding	2/453	29/18639	0.0689655172413793	2.83763416305092	0.156094465803489	0.724076909114249
GO:0061135	endopeptidase regulator activity	7/453	184/18639	0.0380434782608696	1.56532536711777	0.161983545094045	0.740114330658981
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/453	30/18639	0.0666666666666667	2.74304635761589	0.164698599312151	0.740114330658981
GO:0016769	transferase activity, transferring nitrogenous groups	2/453	30/18639	0.0666666666666667	2.74304635761589	0.164698599312151	0.740114330658981
GO:0022839	monoatomic ion-gated channel activity	2/453	30/18639	0.0666666666666667	2.74304635761589	0.164698599312151	0.740114330658981
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/453	30/18639	0.0666666666666667	2.74304635761589	0.164698599312151	0.740114330658981
GO:0008234	cysteine-type peptidase activity	7/453	187/18639	0.0374331550802139	1.54021319545277	0.171414783381166	0.742040998301312
GO:0004540	RNA nuclease activity	5/453	121/18639	0.0413223140495868	1.70023534562969	0.172134204248958	0.742040998301312
GO:0051082	unfolded protein binding	5/453	121/18639	0.0413223140495868	1.70023534562969	0.172134204248958	0.742040998301312
GO:0070063	RNA polymerase binding	3/453	59/18639	0.0508474576271186	2.09215400157144	0.172795733897991	0.742040998301312
GO:0008327	methyl-CpG binding	2/453	31/18639	0.0645161290322581	2.65456099124119	0.173383710312407	0.742040998301312
GO:0017147	Wnt-protein binding	2/453	31/18639	0.0645161290322581	2.65456099124119	0.173383710312407	0.742040998301312
GO:0070325	lipoprotein particle receptor binding	2/453	31/18639	0.0645161290322581	2.65456099124119	0.173383710312407	0.742040998301312
GO:0072349	modified amino acid transmembrane transporter activity	2/453	31/18639	0.0645161290322581	2.65456099124119	0.173383710312407	0.742040998301312
GO:0001098	basal transcription machinery binding	3/453	60/18639	0.05	2.05728476821192	0.17884160246029	0.74464799479165
GO:0001099	basal RNA polymerase II transcription machinery binding	3/453	60/18639	0.05	2.05728476821192	0.17884160246029	0.74464799479165
GO:0022884	macromolecule transmembrane transporter activity	2/453	32/18639	0.0625	2.5716059602649	0.182140808287078	0.74464799479165
GO:0030515	snoRNA binding	2/453	32/18639	0.0625	2.5716059602649	0.182140808287078	0.74464799479165
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/453	32/18639	0.0625	2.5716059602649	0.182140808287078	0.74464799479165
GO:0120015	sterol transfer activity	2/453	32/18639	0.0625	2.5716059602649	0.182140808287078	0.74464799479165
GO:0140142	nucleocytoplasmic carrier activity	2/453	32/18639	0.0625	2.5716059602649	0.182140808287078	0.74464799479165
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	3/453	61/18639	0.0491803278688525	2.02355878840517	0.184944463374777	0.74464799479165
GO:0016836	hydro-lyase activity	3/453	61/18639	0.0491803278688525	2.02355878840517	0.184944463374777	0.74464799479165
GO:0043178	alcohol binding	4/453	92/18639	0.0434782608695652	1.78894327670602	0.185477200811515	0.74464799479165
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/453	33/18639	0.0606060606060606	2.49367850692354	0.190961290114938	0.74464799479165
GO:0005507	copper ion binding	3/453	63/18639	0.0476190476190476	1.9593188268685	0.197309384002876	0.74464799479165
GO:0015035	protein-disulfide reductase activity	2/453	34/18639	0.0588235294117647	2.42033502142579	0.199836926620463	0.74464799479165
GO:0051427	hormone receptor binding	2/453	34/18639	0.0588235294117647	2.42033502142579	0.199836926620463	0.74464799479165
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	5/453	128/18639	0.0390625	1.60725372516556	0.201227319124488	0.74464799479165
GO:0008083	growth factor activity	6/453	162/18639	0.037037037037037	1.52391464311994	0.202371352281606	0.74464799479165
GO:0016229	steroid dehydrogenase activity	2/453	35/18639	0.0571428571428571	2.35118259224219	0.20875984954624	0.74464799479165
GO:0061631	ubiquitin conjugating enzyme activity	2/453	35/18639	0.0571428571428571	2.35118259224219	0.20875984954624	0.74464799479165
GO:0160215	deacylase activity	3/453	65/18639	0.0461538461538462	1.89903209373408	0.20986722783122	0.74464799479165
GO:0004857	enzyme inhibitor activity	13/453	416/18639	0.03125	1.28580298013245	0.214640101917957	0.74464799479165
GO:0016829	lyase activity	7/453	200/18639	0.035	1.44009933774834	0.214848893720126	0.74464799479165
GO:0004033	aldo-keto reductase (NADPH) activity	2/453	36/18639	0.0555555555555556	2.28587196467991	0.217722538935472	0.74464799479165
GO:0004190	aspartic-type endopeptidase activity	2/453	36/18639	0.0555555555555556	2.28587196467991	0.217722538935472	0.74464799479165
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0005345	purine nucleobase transmembrane transporter activity	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0005528	FK506 binding	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0008190	eukaryotic initiation factor 4E binding	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0008239	dipeptidyl-peptidase activity	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0015643	toxic substance binding	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0031419	cobalamin binding	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0032052	bile acid binding	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0035374	chondroitin sulfate binding	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0047429	nucleoside triphosphate diphosphatase activity	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0070097	delta-catenin binding	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0070513	death domain binding	1/453	10/18639	0.1	4.11456953642384	0.218156810456388	0.74464799479165
GO:0005201	extracellular matrix structural constituent	6/453	168/18639	0.0357142857142857	1.46948912015137	0.225476907843192	0.74464799479165
GO:0003712	transcription coregulator activity	15/453	495/18639	0.0303030303030303	1.24683925346177	0.226042736349932	0.74464799479165
GO:0042805	actinin binding	2/453	37/18639	0.0540540540540541	2.22409164131018	0.226717810912434	0.74464799479165
GO:0043394	proteoglycan binding	2/453	37/18639	0.0540540540540541	2.22409164131018	0.226717810912434	0.74464799479165
GO:0070001	aspartic-type peptidase activity	2/453	37/18639	0.0540540540540541	2.22409164131018	0.226717810912434	0.74464799479165
GO:0003714	transcription corepressor activity	7/453	204/18639	0.0343137254901961	1.41186209583171	0.22896298151285	0.74464799479165
GO:0030414	peptidase inhibitor activity	6/453	169/18639	0.0355029585798817	1.46079391825699	0.229409720746666	0.74464799479165
GO:0005109	frizzled binding	2/453	38/18639	0.0526315789473684	2.16556291390728	0.235738805849048	0.74464799479165
GO:0002020	protease binding	5/453	136/18639	0.0367647058823529	1.51270938839112	0.236315957020232	0.74464799479165
GO:0016779	nucleotidyltransferase activity	5/453	136/18639	0.0367647058823529	1.51270938839112	0.236315957020232	0.74464799479165
GO:0019838	growth factor binding	5/453	136/18639	0.0367647058823529	1.51270938839112	0.236315957020232	0.74464799479165
GO:0005536	D-glucose binding	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0008172	S-methyltransferase activity	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0008199	ferric iron binding	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0008432	JUN kinase binding	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0008526	phosphatidylinositol transfer activity	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0015205	nucleobase transmembrane transporter activity	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0015217	ADP transmembrane transporter activity	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0019215	intermediate filament binding	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0032050	clathrin heavy chain binding	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0034511	U3 snoRNA binding	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0050786	RAGE receptor binding	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0180030	inositol phosphate kinase activity	1/453	11/18639	0.0909090909090909	3.74051776038531	0.237168832833502	0.74464799479165
GO:0015036	disulfide oxidoreductase activity	2/453	40/18639	0.05	2.05728476821192	0.253832078937854	0.766093113172478
GO:0004300	enoyl-CoA hydratase activity	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0004859	phospholipase inhibitor activity	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0005049	nuclear export signal receptor activity	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0005165	neurotrophin receptor binding	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0005247	voltage-gated chloride channel activity	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0005527	macrolide binding	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0016801	hydrolase activity, acting on ether bonds	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0016803	ether hydrolase activity	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0017166	vinculin binding	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0035497	cAMP response element binding	1/453	12/18639	0.0833333333333333	3.42880794701987	0.255719537081216	0.766093113172478
GO:0008013	beta-catenin binding	4/453	106/18639	0.0377358490566038	1.5526677495939	0.257401998020808	0.767933761730129
GO:0005319	lipid transporter activity	6/453	178/18639	0.0337078651685393	1.38693355160354	0.265714896445208	0.772065281014421
GO:0042056	chemoattractant activity	2/453	42/18639	0.0476190476190476	1.9593188268685	0.27195353969649	0.772065281014421
GO:0048487	beta-tubulin binding	2/453	42/18639	0.0476190476190476	1.9593188268685	0.27195353969649	0.772065281014421
GO:0002161	aminoacyl-tRNA editing activity	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0008035	high-density lipoprotein particle binding	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0008253	5'-nucleotidase activity	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0009982	pseudouridine synthase activity	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0030955	potassium ion binding	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0031432	titin binding	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0031994	insulin-like growth factor I binding	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0035673	oligopeptide transmembrane transporter activity	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0045159	myosin II binding	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/453	13/18639	0.0769230769230769	3.1650534895568	0.273820092710261	0.772065281014421
GO:0051536	iron-sulfur cluster binding	3/453	76/18639	0.0394736842105263	1.62417218543046	0.281397501416847	0.773339948904529
GO:0004175	endopeptidase activity	12/453	405/18639	0.0296296296296296	1.21913171449595	0.282440056508606	0.773339948904529
GO:0003713	transcription coactivator activity	8/453	256/18639	0.03125	1.28580298013245	0.284899380027699	0.773339948904529
GO:0001046	core promoter sequence-specific DNA binding	2/453	44/18639	0.0454545454545455	1.87025888019266	0.290058861079445	0.773339948904529
GO:0043014	alpha-tubulin binding	2/453	44/18639	0.0454545454545455	1.87025888019266	0.290058861079445	0.773339948904529
GO:0005344	oxygen carrier activity	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:0005347	ATP transmembrane transporter activity	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:0008331	high voltage-gated calcium channel activity	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:0016530	metallochaperone activity	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:0019992	diacylglycerol binding	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:0031404	chloride ion binding	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:0044548	S100 protein binding	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:0070742	C2H2 zinc finger domain binding	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:1901612	cardiolipin binding	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:1990825	sequence-specific mRNA binding	1/453	14/18639	0.0714285714285714	2.93897824030274	0.29148139937848	0.773339948904529
GO:0001221	transcription coregulator binding	4/453	115/18639	0.0347826086956522	1.43115462136481	0.306201176330995	0.776102913118624
GO:0048306	calcium-dependent protein binding	3/453	80/18639	0.0375	1.54296357615894	0.308005944578427	0.776102913118624
GO:0030276	clathrin binding	2/453	46/18639	0.0434782608695652	1.78894327670602	0.308107890297697	0.776102913118624
GO:0000774	adenyl-nucleotide exchange factor activity	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0008242	omega peptidase activity	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0008252	nucleotidase activity	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0015929	hexosaminidase activity	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0016846	carbon-sulfur lyase activity	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0031005	filamin binding	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0033130	acetylcholine receptor binding	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0050780	dopamine receptor binding	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0051371	muscle alpha-actinin binding	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0061578	K63-linked deubiquitinase activity	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0140161	monocarboxylate:sodium symporter activity	1/453	15/18639	0.0666666666666667	2.74304635761589	0.308714093396281	0.776102913118624
GO:0005525	GTP binding	11/453	378/18639	0.0291005291005291	1.19736150530853	0.314106992430102	0.786909155251719
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/453	16/18639	0.0625	2.5716059602649	0.325528554075592	0.78798461614377
GO:0008142	oxysterol binding	1/453	16/18639	0.0625	2.5716059602649	0.325528554075592	0.78798461614377
GO:0015378	sodium:chloride symporter activity	1/453	16/18639	0.0625	2.5716059602649	0.325528554075592	0.78798461614377
GO:0015562	efflux transmembrane transporter activity	1/453	16/18639	0.0625	2.5716059602649	0.325528554075592	0.78798461614377
GO:0016722	oxidoreductase activity, acting on metal ions	1/453	16/18639	0.0625	2.5716059602649	0.325528554075592	0.78798461614377
GO:0043023	ribosomal large subunit binding	1/453	16/18639	0.0625	2.5716059602649	0.325528554075592	0.78798461614377
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/453	16/18639	0.0625	2.5716059602649	0.325528554075592	0.78798461614377
GO:0055102	lipase inhibitor activity	1/453	16/18639	0.0625	2.5716059602649	0.325528554075592	0.78798461614377
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/453	48/18639	0.0416666666666667	1.71440397350993	0.326064351616072	0.78798461614377
GO:0001540	amyloid-beta binding	3/453	83/18639	0.036144578313253	1.48719380834597	0.328024340055617	0.78798461614377
GO:0008135	translation factor activity, RNA binding	3/453	83/18639	0.036144578313253	1.48719380834597	0.328024340055617	0.78798461614377
GO:0032182	ubiquitin-like protein binding	4/453	120/18639	0.0333333333333333	1.37152317880795	0.333737468717899	0.78798461614377
GO:0004527	exonuclease activity	3/453	84/18639	0.0357142857142857	1.46948912015137	0.334697733066007	0.78798461614377
GO:0004860	protein kinase inhibitor activity	3/453	84/18639	0.0357142857142857	1.46948912015137	0.334697733066007	0.78798461614377
GO:0180051	translation factor activity	3/453	84/18639	0.0357142857142857	1.46948912015137	0.334697733066007	0.78798461614377
GO:0016763	pentosyltransferase activity	2/453	49/18639	0.0408163265306122	1.67941613731585	0.334997524400978	0.78798461614377
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/453	17/18639	0.0588235294117647	2.42033502142579	0.341934909926087	0.78798461614377
GO:0005092	GDP-dissociation inhibitor activity	1/453	17/18639	0.0588235294117647	2.42033502142579	0.341934909926087	0.78798461614377
GO:0017110	nucleoside diphosphate phosphatase activity	1/453	17/18639	0.0588235294117647	2.42033502142579	0.341934909926087	0.78798461614377
GO:0019198	transmembrane receptor protein phosphatase activity	1/453	17/18639	0.0588235294117647	2.42033502142579	0.341934909926087	0.78798461614377
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/453	17/18639	0.0588235294117647	2.42033502142579	0.341934909926087	0.78798461614377
GO:0030548	acetylcholine receptor regulator activity	1/453	17/18639	0.0588235294117647	2.42033502142579	0.341934909926087	0.78798461614377
GO:0032183	SUMO binding	1/453	17/18639	0.0588235294117647	2.42033502142579	0.341934909926087	0.78798461614377
GO:0070402	NADPH binding	1/453	17/18639	0.0588235294117647	2.42033502142579	0.341934909926087	0.78798461614377
GO:0070492	oligosaccharide binding	1/453	17/18639	0.0588235294117647	2.42033502142579	0.341934909926087	0.78798461614377
GO:0032813	tumor necrosis factor receptor superfamily binding	2/453	50/18639	0.04	1.64582781456954	0.343895567968448	0.789970969231036
GO:0004866	endopeptidase inhibitor activity	5/453	161/18639	0.031055900621118	1.27781662621858	0.353839548230484	0.796783433873021
GO:0008409	5'-3' exonuclease activity	1/453	18/18639	0.0555555555555556	2.28587196467991	0.357943044702345	0.796783433873021
GO:0008525	phosphatidylcholine transporter activity	1/453	18/18639	0.0555555555555556	2.28587196467991	0.357943044702345	0.796783433873021
GO:0015280	ligand-gated sodium channel activity	1/453	18/18639	0.0555555555555556	2.28587196467991	0.357943044702345	0.796783433873021
GO:0015373	monoatomic anion:sodium symporter activity	1/453	18/18639	0.0555555555555556	2.28587196467991	0.357943044702345	0.796783433873021
GO:0017128	phospholipid scramblase activity	1/453	18/18639	0.0555555555555556	2.28587196467991	0.357943044702345	0.796783433873021
GO:0035615	clathrin adaptor activity	1/453	18/18639	0.0555555555555556	2.28587196467991	0.357943044702345	0.796783433873021
GO:0098641	cadherin binding involved in cell-cell adhesion	1/453	18/18639	0.0555555555555556	2.28587196467991	0.357943044702345	0.796783433873021
GO:0099602	neurotransmitter receptor regulator activity	1/453	18/18639	0.0555555555555556	2.28587196467991	0.357943044702345	0.796783433873021
GO:1990381	ubiquitin-specific protease binding	1/453	18/18639	0.0555555555555556	2.28587196467991	0.357943044702345	0.796783433873021
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/453	52/18639	0.0384615384615385	1.5825267447784	0.36157220027501	0.796875467310416
GO:0005246	calcium channel regulator activity	2/453	53/18639	0.0377358490566038	1.5526677495939	0.370344231299003	0.796875467310416
GO:0030246	carbohydrate binding	8/453	280/18639	0.0285714285714286	1.1755912961211	0.37165063308768	0.796875467310416
GO:0004519	endonuclease activity	4/453	127/18639	0.031496062992126	1.29592741304688	0.372436891652623	0.796875467310416
GO:0019783	ubiquitin-like protein peptidase activity	4/453	127/18639	0.031496062992126	1.29592741304688	0.372436891652623	0.796875467310416
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/453	19/18639	0.0526315789473684	2.16556291390728	0.373562603305526	0.796875467310416
GO:0005229	intracellularly calcium-gated chloride channel activity	1/453	19/18639	0.0526315789473684	2.16556291390728	0.373562603305526	0.796875467310416
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/453	19/18639	0.0526315789473684	2.16556291390728	0.373562603305526	0.796875467310416
GO:0005520	insulin-like growth factor binding	1/453	19/18639	0.0526315789473684	2.16556291390728	0.373562603305526	0.796875467310416
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/453	19/18639	0.0526315789473684	2.16556291390728	0.373562603305526	0.796875467310416
GO:0030506	ankyrin binding	1/453	19/18639	0.0526315789473684	2.16556291390728	0.373562603305526	0.796875467310416
GO:0031420	alkali metal ion binding	1/453	19/18639	0.0526315789473684	2.16556291390728	0.373562603305526	0.796875467310416
GO:0043395	heparan sulfate proteoglycan binding	1/453	19/18639	0.0526315789473684	2.16556291390728	0.373562603305526	0.796875467310416
GO:0141147	intracellularly calcium-gated channel activity	1/453	19/18639	0.0526315789473684	2.16556291390728	0.373562603305526	0.796875467310416
GO:0019210	kinase inhibitor activity	3/453	90/18639	0.0333333333333333	1.37152317880795	0.374609051392101	0.796875467310416
GO:0003925	G protein activity	2/453	54/18639	0.037037037037037	1.52391464311994	0.379068003409179	0.798712443524141
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	2/453	54/18639	0.037037037037037	1.52391464311994	0.379068003409179	0.798712443524141
GO:0050661	NADP binding	2/453	54/18639	0.037037037037037	1.52391464311994	0.379068003409179	0.798712443524141
GO:0019001	guanyl nucleotide binding	11/453	400/18639	0.0275	1.13150662251656	0.381311979693382	0.798712443524141
GO:0032561	guanyl ribonucleotide binding	11/453	400/18639	0.0275	1.13150662251656	0.381311979693382	0.798712443524141
GO:0016247	channel regulator activity	5/453	168/18639	0.0297619047619048	1.22457426679281	0.387626432709418	0.798712443524141
GO:0140313	molecular sequestering activity	2/453	55/18639	0.0363636363636364	1.49620710415412	0.387740681929674	0.798712443524141
GO:0030627	pre-mRNA 5'-splice site binding	1/453	20/18639	0.05	2.05728476821192	0.388802997543045	0.798712443524141
GO:0030742	GTP-dependent protein binding	1/453	20/18639	0.05	2.05728476821192	0.388802997543045	0.798712443524141
GO:0042288	MHC class I protein binding	1/453	20/18639	0.05	2.05728476821192	0.388802997543045	0.798712443524141
GO:0043024	ribosomal small subunit binding	1/453	20/18639	0.05	2.05728476821192	0.388802997543045	0.798712443524141
GO:0061608	nuclear import signal receptor activity	1/453	20/18639	0.05	2.05728476821192	0.388802997543045	0.798712443524141
GO:0030170	pyridoxal phosphate binding	2/453	56/18639	0.0357142857142857	1.46948912015137	0.396359597821747	0.799562487735556
GO:0141108	transporter regulator activity	5/453	170/18639	0.0294117647058824	1.21016751071289	0.397270893494469	0.799562487735556
GO:0004518	nuclease activity	6/453	209/18639	0.0287081339712919	1.18121613485852	0.398205494723386	0.799562487735556
GO:0042562	hormone binding	3/453	94/18639	0.0319148936170213	1.31316049034803	0.40096454170272	0.799562487735556
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/453	21/18639	0.0476190476190476	1.9593188268685	0.403673411749662	0.799562487735556
GO:0005123	death receptor binding	1/453	21/18639	0.0476190476190476	1.9593188268685	0.403673411749662	0.799562487735556
GO:0005248	voltage-gated sodium channel activity	1/453	21/18639	0.0476190476190476	1.9593188268685	0.403673411749662	0.799562487735556
GO:0010314	phosphatidylinositol-5-phosphate binding	1/453	21/18639	0.0476190476190476	1.9593188268685	0.403673411749662	0.799562487735556
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/453	21/18639	0.0476190476190476	1.9593188268685	0.403673411749662	0.799562487735556
GO:0051010	microtubule plus-end binding	1/453	21/18639	0.0476190476190476	1.9593188268685	0.403673411749662	0.799562487735556
GO:0070182	DNA polymerase binding	1/453	21/18639	0.0476190476190476	1.9593188268685	0.403673411749662	0.799562487735556
GO:0072542	protein phosphatase activator activity	1/453	21/18639	0.0476190476190476	1.9593188268685	0.403673411749662	0.799562487735556
GO:0140312	cargo adaptor activity	1/453	21/18639	0.0476190476190476	1.9593188268685	0.403673411749662	0.799562487735556
GO:0070279	vitamin B6 binding	2/453	57/18639	0.0350877192982456	1.44370860927152	0.404922241338044	0.799832669016631
GO:0008408	3'-5' exonuclease activity	2/453	58/18639	0.0344827586206897	1.41881708152546	0.413426255886356	0.814393090362438
GO:0005243	gap junction channel activity	1/453	22/18639	0.0454545454545455	1.87025888019266	0.418182808273316	0.817047388990529
GO:0015377	chloride:monoatomic cation symporter activity	1/453	22/18639	0.0454545454545455	1.87025888019266	0.418182808273316	0.817047388990529
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/453	22/18639	0.0454545454545455	1.87025888019266	0.418182808273316	0.817047388990529
GO:0036002	pre-mRNA binding	2/453	59/18639	0.0338983050847458	1.39476933438096	0.421869432096474	0.822016589911557
GO:0016741	transferase activity, transferring one-carbon groups	6/453	215/18639	0.027906976744186	1.14825196365316	0.424196260429615	0.822360877523845
GO:0004252	serine-type endopeptidase activity	5/453	176/18639	0.0284090909090909	1.16891180012041	0.426096632129713	0.822360877523845
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	2/453	60/18639	0.0333333333333333	1.37152317880795	0.430249702083928	0.822360877523845
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/453	60/18639	0.0333333333333333	1.37152317880795	0.430249702083928	0.822360877523845
GO:0000295	adenine nucleotide transmembrane transporter activity	1/453	23/18639	0.0434782608695652	1.78894327670602	0.432339932828948	0.822360877523845
GO:0003887	DNA-directed DNA polymerase activity	1/453	23/18639	0.0434782608695652	1.78894327670602	0.432339932828948	0.822360877523845
GO:0005283	amino acid:sodium symporter activity	1/453	23/18639	0.0434782608695652	1.78894327670602	0.432339932828948	0.822360877523845
GO:0017134	fibroblast growth factor binding	1/453	23/18639	0.0434782608695652	1.78894327670602	0.432339932828948	0.822360877523845
GO:0140103	catalytic activity, acting on a glycoprotein	1/453	23/18639	0.0434782608695652	1.78894327670602	0.432339932828948	0.822360877523845
GO:0140101	catalytic activity, acting on a tRNA	4/453	139/18639	0.0287769784172662	1.1840487874601	0.438189238888121	0.824638141082718
GO:0015026	coreceptor activity	2/453	61/18639	0.0327868852459016	1.34903919227011	0.438565133904578	0.824638141082718
GO:0043130	ubiquitin binding	3/453	100/18639	0.03	1.23437086092715	0.439870424305285	0.824638141082718
GO:0005540	hyaluronic acid binding	1/453	24/18639	0.0416666666666667	1.71440397350993	0.446153319723473	0.824638141082718
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/453	24/18639	0.0416666666666667	1.71440397350993	0.446153319723473	0.824638141082718
GO:0035035	histone acetyltransferase binding	1/453	24/18639	0.0416666666666667	1.71440397350993	0.446153319723473	0.824638141082718
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/453	24/18639	0.0416666666666667	1.71440397350993	0.446153319723473	0.824638141082718
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/453	24/18639	0.0416666666666667	1.71440397350993	0.446153319723473	0.824638141082718
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/453	24/18639	0.0416666666666667	1.71440397350993	0.446153319723473	0.824638141082718
GO:0050431	transforming growth factor beta binding	1/453	24/18639	0.0416666666666667	1.71440397350993	0.446153319723473	0.824638141082718
GO:0070300	phosphatidic acid binding	1/453	24/18639	0.0416666666666667	1.71440397350993	0.446153319723473	0.824638141082718
GO:0008483	transaminase activity	1/453	25/18639	0.04	1.64582781456954	0.459631296955021	0.834532582097627
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/453	25/18639	0.04	1.64582781456954	0.459631296955021	0.834532582097627
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/453	25/18639	0.04	1.64582781456954	0.459631296955021	0.834532582097627
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/453	25/18639	0.04	1.64582781456954	0.459631296955021	0.834532582097627
GO:0017056	structural constituent of nuclear pore	1/453	25/18639	0.04	1.64582781456954	0.459631296955021	0.834532582097627
GO:0019211	phosphatase activator activity	1/453	25/18639	0.04	1.64582781456954	0.459631296955021	0.834532582097627
GO:0047617	fatty acyl-CoA hydrolase activity	1/453	25/18639	0.04	1.64582781456954	0.459631296955021	0.834532582097627
GO:0004536	DNA nuclease activity	2/453	64/18639	0.03125	1.28580298013245	0.463105008710124	0.838721665648814
GO:0140098	catalytic activity, acting on RNA	10/453	387/18639	0.0258397932816537	1.06319626264182	0.467049684291473	0.839333954728897
GO:0004435	phosphatidylinositol phospholipase C activity	1/453	26/18639	0.0384615384615385	1.5825267447784	0.472781991189435	0.839333954728897
GO:0004529	DNA exonuclease activity	1/453	26/18639	0.0384615384615385	1.5825267447784	0.472781991189435	0.839333954728897
GO:0005227	calcium-activated cation channel activity	1/453	26/18639	0.0384615384615385	1.5825267447784	0.472781991189435	0.839333954728897
GO:0008198	ferrous iron binding	1/453	26/18639	0.0384615384615385	1.5825267447784	0.472781991189435	0.839333954728897
GO:0015216	purine nucleotide transmembrane transporter activity	1/453	26/18639	0.0384615384615385	1.5825267447784	0.472781991189435	0.839333954728897
GO:0016289	acyl-CoA hydrolase activity	1/453	26/18639	0.0384615384615385	1.5825267447784	0.472781991189435	0.839333954728897
GO:0050681	nuclear androgen receptor binding	1/453	26/18639	0.0384615384615385	1.5825267447784	0.472781991189435	0.839333954728897
GO:0005385	zinc ion transmembrane transporter activity	1/453	27/18639	0.037037037037037	1.52391464311994	0.485613332616995	0.851960329952232
GO:0008266	poly(U) RNA binding	1/453	27/18639	0.037037037037037	1.52391464311994	0.485613332616995	0.851960329952232
GO:0023026	MHC class II protein complex binding	1/453	27/18639	0.037037037037037	1.52391464311994	0.485613332616995	0.851960329952232
GO:0035255	ionotropic glutamate receptor binding	1/453	27/18639	0.037037037037037	1.52391464311994	0.485613332616995	0.851960329952232
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/453	67/18639	0.0298507462686567	1.22822971236533	0.487003749110386	0.851960329952232
GO:0050840	extracellular matrix binding	2/453	67/18639	0.0298507462686567	1.22822971236533	0.487003749110386	0.851960329952232
GO:0005085	guanyl-nucleotide exchange factor activity	6/453	230/18639	0.0260869565217391	1.07336596602361	0.48825890076446	0.852082887499143
GO:0005496	steroid binding	3/453	108/18639	0.0277777777777778	1.14293598233996	0.490142469454059	0.853298875393387
GO:0030145	manganese ion binding	2/453	68/18639	0.0294117647058824	1.21016751071289	0.49482155667415	0.858891294769118
GO:0019789	SUMO transferase activity	1/453	28/18639	0.0357142857142857	1.46948912015137	0.498133059692243	0.858891294769118
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/453	28/18639	0.0357142857142857	1.46948912015137	0.498133059692243	0.858891294769118
GO:0097718	disordered domain specific binding	1/453	28/18639	0.0357142857142857	1.46948912015137	0.498133059692243	0.858891294769118
GO:0005126	cytokine receptor binding	7/453	275/18639	0.0254545454545455	1.04734497290789	0.504231057870784	0.85951980583029
GO:0016782	transferase activity, transferring sulphur-containing groups	2/453	70/18639	0.0285714285714286	1.1755912961211	0.510228222039159	0.85951980583029
GO:0097110	scaffold protein binding	2/453	70/18639	0.0285714285714286	1.1755912961211	0.510228222039159	0.85951980583029
GO:0004629	phospholipase C activity	1/453	29/18639	0.0344827586206897	1.41881708152546	0.510348723759698	0.85951980583029
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/453	29/18639	0.0344827586206897	1.41881708152546	0.510348723759698	0.85951980583029
GO:0005416	amino acid:monoatomic cation symporter activity	1/453	29/18639	0.0344827586206897	1.41881708152546	0.510348723759698	0.85951980583029
GO:0035250	UDP-galactosyltransferase activity	1/453	29/18639	0.0344827586206897	1.41881708152546	0.510348723759698	0.85951980583029
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/453	29/18639	0.0344827586206897	1.41881708152546	0.510348723759698	0.85951980583029
GO:0097472	cyclin-dependent protein kinase activity	1/453	29/18639	0.0344827586206897	1.41881708152546	0.510348723759698	0.85951980583029
GO:0008236	serine-type peptidase activity	5/453	194/18639	0.0257731958762887	1.06045606608862	0.510451957009087	0.85951980583029
GO:0005200	structural constituent of cytoskeleton	3/453	112/18639	0.0267857142857143	1.10211684011353	0.514440550185816	0.864212045756078
GO:0001968	fibronectin binding	1/453	30/18639	0.0333333333333333	1.37152317880795	0.522267693568234	0.869237202952686
GO:0008187	poly-pyrimidine tract binding	1/453	30/18639	0.0333333333333333	1.37152317880795	0.522267693568234	0.869237202952686
GO:0015215	nucleotide transmembrane transporter activity	1/453	30/18639	0.0333333333333333	1.37152317880795	0.522267693568234	0.869237202952686
GO:0051721	protein phosphatase 2A binding	1/453	30/18639	0.0333333333333333	1.37152317880795	0.522267693568234	0.869237202952686
GO:0017171	serine hydrolase activity	5/453	198/18639	0.0252525252525253	1.03903271121814	0.52854464659151	0.87765265796604
GO:0101005	deubiquitinase activity	3/453	115/18639	0.0260869565217391	1.07336596602361	0.532253256326385	0.878425761573437
GO:0043539	protein serine/threonine kinase activator activity	2/453	73/18639	0.0273972602739726	1.12727932504763	0.532753230134465	0.878425761573437
GO:0005164	tumor necrosis factor receptor binding	1/453	31/18639	0.032258064516129	1.32728049562059	0.533897159676762	0.878425761573437
GO:0005184	neuropeptide hormone activity	1/453	31/18639	0.032258064516129	1.32728049562059	0.533897159676762	0.878425761573437
GO:0046982	protein heterodimerization activity	9/453	369/18639	0.024390243902439	1.00355354546923	0.542983031614915	0.884492250404219
GO:1990782	protein tyrosine kinase binding	3/453	117/18639	0.0256410256410256	1.05501782985227	0.543922418242602	0.884492250404219
GO:0008378	galactosyltransferase activity	1/453	32/18639	0.03125	1.28580298013245	0.545244138753848	0.884492250404219
GO:0015106	bicarbonate transmembrane transporter activity	1/453	32/18639	0.03125	1.28580298013245	0.545244138753848	0.884492250404219
GO:0031369	translation initiation factor binding	1/453	32/18639	0.03125	1.28580298013245	0.545244138753848	0.884492250404219
GO:0160041	neuropeptide activity	1/453	32/18639	0.03125	1.28580298013245	0.545244138753848	0.884492250404219
GO:0019003	GDP binding	2/453	75/18639	0.0266666666666667	1.09721854304636	0.547372053031902	0.884492250404219
GO:0099106	ion channel regulator activity	4/453	160/18639	0.025	1.02864238410596	0.547425662628481	0.884492250404219
GO:0019207	kinase regulator activity	7/453	287/18639	0.024390243902439	1.00355354546923	0.549503534882786	0.884938580265375
GO:0005543	phospholipid binding	12/453	497/18639	0.0241448692152917	0.993457433341773	0.550563760488215	0.884938580265375
GO:0098631	cell adhesion mediator activity	2/453	76/18639	0.0263157894736842	1.08278145695364	0.554560554426903	0.884938580265375
GO:0008168	methyltransferase activity	5/453	204/18639	0.0245098039215686	1.00847292559408	0.555113218087829	0.884938580265375
GO:0019956	chemokine binding	1/453	33/18639	0.0303030303030303	1.24683925346177	0.556315477773814	0.884938580265375
GO:0030296	protein tyrosine kinase activator activity	1/453	33/18639	0.0303030303030303	1.24683925346177	0.556315477773814	0.884938580265375
GO:0003924	GTPase activity	8/453	331/18639	0.0241691842900302	0.99445789399972	0.556317438497844	0.884938580265375
GO:0042277	peptide binding	6/453	249/18639	0.0240963855421687	0.991462538897311	0.565760237611671	0.890300742319608
GO:0140104	molecular carrier activity	6/453	249/18639	0.0240963855421687	0.991462538897311	0.565760237611671	0.890300742319608
GO:0003697	single-stranded DNA binding	3/453	121/18639	0.0247933884297521	1.02014120737781	0.566745512893028	0.890300742319608
GO:0008376	acetylgalactosaminyltransferase activity	1/453	34/18639	0.0294117647058824	1.21016751071289	0.567117858111795	0.890300742319608
GO:0016831	carboxy-lyase activity	1/453	34/18639	0.0294117647058824	1.21016751071289	0.567117858111795	0.890300742319608
GO:0019825	oxygen binding	1/453	34/18639	0.0294117647058824	1.21016751071289	0.567117858111795	0.890300742319608
GO:0000175	3'-5'-RNA exonuclease activity	1/453	35/18639	0.0285714285714286	1.1755912961211	0.577657799540193	0.900945678675486
GO:0005343	organic acid:sodium symporter activity	1/453	35/18639	0.0285714285714286	1.1755912961211	0.577657799540193	0.900945678675486
GO:0034061	DNA polymerase activity	1/453	35/18639	0.0285714285714286	1.1755912961211	0.577657799540193	0.900945678675486
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	4/453	167/18639	0.0239520958083832	0.985525637466788	0.581338709108293	0.903396382132003
GO:0001664	G protein-coupled receptor binding	7/453	297/18639	0.0235690235690236	0.969763863803599	0.585838231136738	0.903396382132003
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/453	36/18639	0.0277777777777778	1.14293598233996	0.587941664128899	0.903396382132003
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/453	36/18639	0.0277777777777778	1.14293598233996	0.587941664128899	0.903396382132003
GO:0045505	dynein intermediate chain binding	1/453	36/18639	0.0277777777777778	1.14293598233996	0.587941664128899	0.903396382132003
GO:0019887	protein kinase regulator activity	6/453	255/18639	0.0235294117647059	0.968134008570316	0.589053649961652	0.903396382132003
GO:0001618	virus receptor activity	2/453	81/18639	0.0246913580246914	1.01594309541329	0.589280811154255	0.903396382132003
GO:0030971	receptor tyrosine kinase binding	2/453	81/18639	0.0246913580246914	1.01594309541329	0.589280811154255	0.903396382132003
GO:0140272	exogenous protein binding	2/453	82/18639	0.024390243902439	1.00355354546923	0.595979084178821	0.908973572044578
GO:0019213	deacetylase activity	1/453	37/18639	0.027027027027027	1.11204582065509	0.597975660051579	0.908973572044578
GO:0023023	MHC protein complex binding	1/453	37/18639	0.027027027027027	1.11204582065509	0.597975660051579	0.908973572044578
GO:0030280	structural constituent of skin epidermis	1/453	37/18639	0.027027027027027	1.11204582065509	0.597975660051579	0.908973572044578
GO:0031490	chromatin DNA binding	3/453	128/18639	0.0234375	0.964352235099338	0.604956526191468	0.914191721278061
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/453	38/18639	0.0263157894736842	1.08278145695364	0.607765845300296	0.914191721278061
GO:0042162	telomeric DNA binding	1/453	38/18639	0.0263157894736842	1.08278145695364	0.607765845300296	0.914191721278061
GO:0042887	amide transmembrane transporter activity	1/453	38/18639	0.0263157894736842	1.08278145695364	0.607765845300296	0.914191721278061
GO:0043531	ADP binding	1/453	38/18639	0.0263157894736842	1.08278145695364	0.607765845300296	0.914191721278061
GO:0000217	DNA secondary structure binding	1/453	39/18639	0.0256410256410256	1.05501782985227	0.61731813131067	0.926621579149002
GO:0004532	RNA exonuclease activity	1/453	40/18639	0.025	1.02864238410596	0.626638286499717	0.930894479324993
GO:0061791	GTPase motor activity	1/453	40/18639	0.025	1.02864238410596	0.626638286499717	0.930894479324993
GO:0071855	neuropeptide receptor binding	1/453	40/18639	0.025	1.02864238410596	0.626638286499717	0.930894479324993
GO:0071949	FAD binding	1/453	40/18639	0.025	1.02864238410596	0.626638286499717	0.930894479324993
GO:1990606	membrane scission GTPase motor activity	1/453	40/18639	0.025	1.02864238410596	0.626638286499717	0.930894479324993
GO:0001530	lipopolysaccharide binding	1/453	41/18639	0.024390243902439	1.00355354546923	0.635731939718472	0.936662427577011
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/453	41/18639	0.024390243902439	1.00355354546923	0.635731939718472	0.936662427577011
GO:0042169	SH2 domain binding	1/453	41/18639	0.024390243902439	1.00355354546923	0.635731939718472	0.936662427577011
GO:0042287	MHC protein binding	1/453	41/18639	0.024390243902439	1.00355354546923	0.635731939718472	0.936662427577011
GO:0003727	single-stranded RNA binding	2/453	89/18639	0.0224719101123595	0.924622367735695	0.640572630772028	0.941864461196499
GO:0004520	DNA endonuclease activity	1/453	42/18639	0.0238095238095238	0.979659413434248	0.644604583621447	0.942013608991505
GO:0031492	nucleosomal DNA binding	1/453	42/18639	0.0238095238095238	0.979659413434248	0.644604583621447	0.942013608991505
GO:0035198	miRNA binding	1/453	42/18639	0.0238095238095238	0.979659413434248	0.644604583621447	0.942013608991505
GO:0016922	nuclear receptor binding	3/453	137/18639	0.0218978102189781	0.90100062841398	0.650702896269192	0.946965876108031
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/453	91/18639	0.021978021978022	0.904300997016229	0.652581181268685	0.946965876108031
GO:0072341	modified amino acid binding	2/453	91/18639	0.021978021978022	0.904300997016229	0.652581181268685	0.946965876108031
GO:0005245	voltage-gated calcium channel activity	1/453	43/18639	0.0232558139534884	0.956876636377637	0.653261577954914	0.946965876108031
GO:0001223	transcription coactivator binding	1/453	44/18639	0.0227272727272727	0.935129440096328	0.661708152765972	0.953443210097663
GO:0016790	thiolester hydrolase activity	1/453	44/18639	0.0227272727272727	0.935129440096328	0.661708152765972	0.953443210097663
GO:0030547	signaling receptor inhibitor activity	1/453	44/18639	0.0227272727272727	0.935129440096328	0.661708152765972	0.953443210097663
GO:0004715	non-membrane spanning protein tyrosine kinase activity	1/453	45/18639	0.0222222222222222	0.914348785871965	0.669949411534297	0.957641405354194
GO:0046915	transition metal ion transmembrane transporter activity	1/453	45/18639	0.0222222222222222	0.914348785871965	0.669949411534297	0.957641405354194
GO:0051539	4 iron, 4 sulfur cluster binding	1/453	45/18639	0.0222222222222222	0.914348785871965	0.669949411534297	0.957641405354194
GO:0140303	intramembrane lipid transporter activity	1/453	45/18639	0.0222222222222222	0.914348785871965	0.669949411534297	0.957641405354194
GO:0004867	serine-type endopeptidase inhibitor activity	2/453	95/18639	0.0210526315789474	0.866225165562914	0.675637161663104	0.963855395309071
GO:0019955	cytokine binding	3/453	144/18639	0.0208333333333333	0.857201986754967	0.683588682636638	0.968193521194156
GO:0061749	forked DNA-dependent helicase activity	1/453	47/18639	0.0212765957446809	0.87544032689869	0.685835780288494	0.968193521194156
GO:0099095	ligand-gated monoatomic anion channel activity	1/453	47/18639	0.0212765957446809	0.87544032689869	0.685835780288494	0.968193521194156
GO:1990518	single-stranded 3'-5' DNA helicase activity	1/453	47/18639	0.0212765957446809	0.87544032689869	0.685835780288494	0.968193521194156
GO:0008170	N-methyltransferase activity	2/453	98/18639	0.0204081632653061	0.839708068657927	0.69210147444773	0.968193521194156
GO:0009378	four-way junction helicase activity	1/453	48/18639	0.0208333333333333	0.857201986754967	0.693490491536844	0.968193521194156
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/453	48/18639	0.0208333333333333	0.857201986754967	0.693490491536844	0.968193521194156
GO:0032266	phosphatidylinositol-3-phosphate binding	1/453	48/18639	0.0208333333333333	0.857201986754967	0.693490491536844	0.968193521194156
GO:0036121	double-stranded DNA helicase activity	1/453	48/18639	0.0208333333333333	0.857201986754967	0.693490491536844	0.968193521194156
GO:0043138	3'-5' DNA helicase activity	1/453	48/18639	0.0208333333333333	0.857201986754967	0.693490491536844	0.968193521194156
GO:0140693	molecular condensate scaffold activity	1/453	48/18639	0.0208333333333333	0.857201986754967	0.693490491536844	0.968193521194156
GO:0001222	transcription corepressor binding	1/453	49/18639	0.0204081632653061	0.839708068657927	0.700959095018841	0.972952875132329
GO:0035254	glutamate receptor binding	1/453	49/18639	0.0204081632653061	0.839708068657927	0.700959095018841	0.972952875132329
GO:0060590	ATPase regulator activity	1/453	49/18639	0.0204081632653061	0.839708068657927	0.700959095018841	0.972952875132329
GO:0008509	monoatomic anion transmembrane transporter activity	3/453	149/18639	0.0201342281879195	0.828436819414196	0.70563234127017	0.977406813919778
GO:0015605	organophosphate ester transmembrane transporter activity	1/453	50/18639	0.02	0.822913907284768	0.708246105774971	0.977406813919778
GO:0048020	CCR chemokine receptor binding	1/453	50/18639	0.02	0.822913907284768	0.708246105774971	0.977406813919778
GO:0003743	translation initiation factor activity	1/453	51/18639	0.0196078431372549	0.806778340475263	0.71535592954623	0.977834436014714
GO:0005048	signal sequence binding	1/453	51/18639	0.0196078431372549	0.806778340475263	0.71535592954623	0.977834436014714
GO:0005272	sodium channel activity	1/453	51/18639	0.0196078431372549	0.806778340475263	0.71535592954623	0.977834436014714
GO:0016597	amino acid binding	1/453	51/18639	0.0196078431372549	0.806778340475263	0.71535592954623	0.977834436014714
GO:0016830	carbon-carbon lyase activity	1/453	51/18639	0.0196078431372549	0.806778340475263	0.71535592954623	0.977834436014714
GO:0005253	monoatomic anion channel activity	2/453	103/18639	0.0194174757281553	0.798945541053173	0.718006092253633	0.979594649583229
GO:0042393	histone binding	5/453	247/18639	0.0202429149797571	0.832908813041263	0.720426841145005	0.981035793150111
GO:0005506	iron ion binding	3/453	154/18639	0.0194805194805195	0.801539520082566	0.726483792797994	0.983480181845811
GO:0004864	protein phosphatase inhibitor activity	1/453	53/18639	0.0188679245283019	0.776333874796951	0.729061108378049	0.983480181845811
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/453	53/18639	0.0188679245283019	0.776333874796951	0.729061108378049	0.983480181845811
GO:0017046	peptide hormone binding	1/453	53/18639	0.0188679245283019	0.776333874796951	0.729061108378049	0.983480181845811
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/453	53/18639	0.0188679245283019	0.776333874796951	0.729061108378049	0.983480181845811
GO:0015485	cholesterol binding	1/453	54/18639	0.0185185185185185	0.761957321559971	0.735664751868028	0.986833874240881
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	1/453	54/18639	0.0185185185185185	0.761957321559971	0.735664751868028	0.986833874240881
GO:0140463	chromatin-protein adaptor activity	1/453	54/18639	0.0185185185185185	0.761957321559971	0.735664751868028	0.986833874240881
GO:0019888	protein phosphatase regulator activity	2/453	107/18639	0.0186915887850467	0.769078418023148	0.737389619977469	0.987305655053632
GO:0004843	cysteine-type deubiquitinase activity	2/453	108/18639	0.0185185185185185	0.761957321559971	0.742054660553383	0.989935994719773
GO:0098632	cell-cell adhesion mediator activity	1/453	55/18639	0.0181818181818182	0.748103552077062	0.74210779020022	0.989935994719773
GO:0019212	phosphatase inhibitor activity	1/453	56/18639	0.0178571428571429	0.734744560075686	0.748394120970737	0.996472912922148
GO:0051015	actin filament binding	4/453	209/18639	0.0191387559808612	0.787477423239013	0.751016871357707	0.997310294767409
GO:0140297	DNA-binding transcription factor binding	10/453	488/18639	0.0204918032786885	0.84314949516882	0.751797190214097	0.997310294767409
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/453	57/18639	0.0175438596491228	0.721854304635762	0.75452754739275	0.999088962385611
GO:0017116	single-stranded DNA helicase activity	1/453	58/18639	0.0172413793103448	0.709408540762731	0.760511780577072	0.999556182771441
GO:0061980	regulatory RNA binding	1/453	58/18639	0.0172413793103448	0.709408540762731	0.760511780577072	0.999556182771441
GO:0004879	nuclear receptor activity	1/453	59/18639	0.0169491525423729	0.697384667190482	0.766350441757772	0.999556182771441
GO:0015459	potassium channel regulator activity	1/453	59/18639	0.0169491525423729	0.697384667190482	0.766350441757772	0.999556182771441
GO:0003730	mRNA 3'-UTR binding	5/453	262/18639	0.0190839694656489	0.785223193974016	0.766526405615059	0.999556182771441
GO:0098531	ligand-modulated transcription factor activity	1/453	60/18639	0.0166666666666667	0.685761589403973	0.772047064464109	0.999556182771441
GO:0035401	histone H3Y41 kinase activity	2/453	115/18639	0.0173913043478261	0.715577310682407	0.772760994911438	0.999556182771441
GO:0140801	histone H2AXY142 kinase activity	2/453	115/18639	0.0173913043478261	0.715577310682407	0.772760994911438	0.999556182771441
GO:0015294	solute:monoatomic cation symporter activity	2/453	116/18639	0.0172413793103448	0.709408540762731	0.776877699233804	0.999556182771441
GO:0019905	syntaxin binding	1/453	61/18639	0.0163934426229508	0.674519596135056	0.777605096640101	0.999556182771441
GO:0016757	glycosyltransferase activity	5/453	267/18639	0.0187265917602996	0.770518639779746	0.780549216187821	0.999556182771441
GO:0019208	phosphatase regulator activity	2/453	117/18639	0.0170940170940171	0.703345219901511	0.780929095424955	0.999556182771441
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	5/453	268/18639	0.0186567164179104	0.767643570228329	0.783274618482153	0.999556182771441
GO:1901682	sulfur compound transmembrane transporter activity	1/453	63/18639	0.0158730158730159	0.653106275622832	0.788318765611785	0.999556182771441
GO:0005244	voltage-gated monoatomic ion channel activity	3/453	173/18639	0.0173410404624277	0.713509168165984	0.795279508017551	0.999556182771441
GO:0015108	chloride transmembrane transporter activity	2/453	121/18639	0.0165289256198347	0.680094138251874	0.796496327311789	0.999556182771441
GO:0038024	cargo receptor activity	1/453	65/18639	0.0153846153846154	0.63301069791136	0.798517397884021	0.999556182771441
GO:0008528	G protein-coupled peptide receptor activity	2/453	122/18639	0.0163934426229508	0.674519596135056	0.800232249085292	0.999556182771441
GO:0004721	phosphoprotein phosphatase activity	3/453	175/18639	0.0171428571428571	0.705354777672658	0.80160749137828	0.999556182771441
GO:0022832	voltage-gated channel activity	3/453	175/18639	0.0171428571428571	0.705354777672658	0.80160749137828	0.999556182771441
GO:0001217	DNA-binding transcription repressor activity	5/453	278/18639	0.0179856115107914	0.740030492162561	0.80910603368013	0.999556182771441
GO:0032934	sterol binding	1/453	68/18639	0.0147058823529412	0.605083755356447	0.812903374391982	0.999556182771441
GO:0140223	general transcription initiation factor activity	1/453	68/18639	0.0147058823529412	0.605083755356447	0.812903374391982	0.999556182771441
GO:0002039	p53 binding	1/453	69/18639	0.0144927536231884	0.596314425568673	0.817467198171015	0.999556182771441
GO:0042826	histone deacetylase binding	2/453	127/18639	0.015748031496063	0.647963706523439	0.818013701910119	0.999556182771441
GO:0001653	peptide receptor activity	2/453	128/18639	0.015625	0.642901490066225	0.821395561842161	0.999556182771441
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/453	70/18639	0.0142857142857143	0.587795648060549	0.821919936955535	0.999556182771441
GO:0016278	lysine N-methyltransferase activity	1/453	70/18639	0.0142857142857143	0.587795648060549	0.821919936955535	0.999556182771441
GO:0035591	signaling adaptor activity	2/453	129/18639	0.0155038759689922	0.637917757585092	0.824721006541654	0.999556182771441
GO:0140299	molecular sensor activity	1/453	71/18639	0.0140845070422535	0.579516836116034	0.826264288754724	0.999556182771441
GO:0016298	lipase activity	2/453	130/18639	0.0153846153846154	0.63301069791136	0.827990773117082	0.999556182771441
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/453	130/18639	0.0153846153846154	0.63301069791136	0.827990773117082	0.999556182771441
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	2/453	130/18639	0.0153846153846154	0.63301069791136	0.827990773117082	0.999556182771441
GO:0015631	tubulin binding	7/453	385/18639	0.0181818181818182	0.748103552077062	0.829944768561003	0.999556182771441
GO:0042379	chemokine receptor binding	1/453	72/18639	0.0138888888888889	0.571467991169978	0.830502886190857	0.999556182771441
GO:0005262	calcium channel activity	2/453	131/18639	0.0152671755725191	0.628178555179212	0.831205596254235	0.999556182771441
GO:0003678	DNA helicase activity	1/453	74/18639	0.0135135135135135	0.556022910327546	0.838673030977734	0.999556182771441
GO:0003684	damaged DNA binding	1/453	74/18639	0.0135135135135135	0.556022910327546	0.838673030977734	0.999556182771441
GO:0031491	nucleosome binding	1/453	74/18639	0.0135135135135135	0.556022910327546	0.838673030977734	0.999556182771441
GO:0048029	monosaccharide binding	1/453	74/18639	0.0135135135135135	0.556022910327546	0.838673030977734	0.999556182771441
GO:0019902	phosphatase binding	3/453	190/18639	0.0157894736842105	0.649668874172185	0.844009593866157	0.999556182771441
GO:0044325	transmembrane transporter binding	2/453	136/18639	0.0147058823529412	0.605083755356447	0.846481066198724	0.999556182771441
GO:0099094	ligand-gated monoatomic cation channel activity	2/453	136/18639	0.0147058823529412	0.605083755356447	0.846481066198724	0.999556182771441
GO:0140789	histone phosphatase activity	2/453	136/18639	0.0147058823529412	0.605083755356447	0.846481066198724	0.999556182771441
GO:0030295	protein kinase activator activity	2/453	139/18639	0.0143884892086331	0.592024393730049	0.855033344168741	0.999556182771441
GO:0016755	aminoacyltransferase activity	9/453	496/18639	0.0181451612903226	0.746595278786584	0.855203489763253	0.999556182771441
GO:0015370	solute:sodium symporter activity	1/453	79/18639	0.0126582278481013	0.520831586889094	0.857420068298936	0.999556182771441
GO:0046332	SMAD binding	1/453	79/18639	0.0126582278481013	0.520831586889094	0.857420068298936	0.999556182771441
GO:0004713	protein tyrosine kinase activity	2/453	140/18639	0.0142857142857143	0.587795648060549	0.857786193186565	0.999556182771441
GO:0016758	hexosyltransferase activity	3/453	197/18639	0.0152284263959391	0.626584193364037	0.860959694040457	0.999556182771441
GO:0033192	calmodulin-dependent protein phosphatase activity	1/453	81/18639	0.0123456790123457	0.507971547706647	0.864295304052245	0.999556182771441
GO:0140791	histone H2AXS140 phosphatase activity	1/453	81/18639	0.0123456790123457	0.507971547706647	0.864295304052245	0.999556182771441
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	1/453	81/18639	0.0123456790123457	0.507971547706647	0.864295304052245	0.999556182771441
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	1/453	81/18639	0.0123456790123457	0.507971547706647	0.864295304052245	0.999556182771441
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	1/453	81/18639	0.0123456790123457	0.507971547706647	0.864295304052245	0.999556182771441
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	1/453	81/18639	0.0123456790123457	0.507971547706647	0.864295304052245	0.999556182771441
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	1/453	81/18639	0.0123456790123457	0.507971547706647	0.864295304052245	0.999556182771441
GO:1990439	MAP kinase serine/threonine phosphatase activity	1/453	81/18639	0.0123456790123457	0.507971547706647	0.864295304052245	0.999556182771441
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	1/453	82/18639	0.0121951219512195	0.501776772734615	0.867607849976608	0.999556182771441
GO:0033549	MAP kinase phosphatase activity	1/453	82/18639	0.0121951219512195	0.501776772734615	0.867607849976608	0.999556182771441
GO:0019903	protein phosphatase binding	2/453	144/18639	0.0138888888888889	0.571467991169978	0.868326549983557	0.999556182771441
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	1/453	83/18639	0.0120481927710843	0.495731269448656	0.870839710943391	0.999556182771441
GO:0005254	chloride channel activity	1/453	83/18639	0.0120481927710843	0.495731269448656	0.870839710943391	0.999556182771441
GO:0008194	UDP-glycosyltransferase activity	2/453	145/18639	0.0137931034482759	0.567526832610185	0.870847291804467	0.999556182771441
GO:0015293	symporter activity	2/453	146/18639	0.0136986301369863	0.563639662523814	0.873323640356636	0.999556182771441
GO:0017018	myosin phosphatase activity	1/453	84/18639	0.0119047619047619	0.489829706717124	0.873992847984922	0.999556182771441
GO:0015085	calcium ion transmembrane transporter activity	2/453	147/18639	0.0136054421768707	0.559805379105284	0.875756258463551	0.999556182771441
GO:0019209	kinase activator activity	2/453	148/18639	0.0135135135135135	0.556022910327546	0.878145803035298	0.999556182771441
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/453	86/18639	0.0116279069767442	0.478438318188819	0.880070557775487	0.999556182771441
GO:0050660	flavin adenine dinucleotide binding	1/453	86/18639	0.0116279069767442	0.478438318188819	0.880070557775487	0.999556182771441
GO:0008081	phosphoric diester hydrolase activity	1/453	87/18639	0.0114942528735632	0.472939027175154	0.882998819368098	0.999556182771441
GO:0051020	GTPase binding	5/453	315/18639	0.0158730158730159	0.653106275622832	0.883995329816532	0.999556182771441
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	1/453	89/18639	0.0112359550561798	0.462311183867847	0.888643044966398	0.999556182771441
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	1/453	89/18639	0.0112359550561798	0.462311183867847	0.888643044966398	0.999556182771441
GO:0003774	cytoskeletal motor activity	2/453	153/18639	0.0130718954248366	0.537852226983509	0.889469988321373	0.999556182771441
GO:0140793	histone H2AXY142 phosphatase activity	1/453	90/18639	0.0111111111111111	0.457174392935982	0.891362435835952	0.999556182771441
GO:0008514	organic anion transmembrane transporter activity	4/453	269/18639	0.0148698884758364	0.611831901326965	0.895340752370597	0.999556182771441
GO:0051213	dioxygenase activity	1/453	93/18639	0.010752688172043	0.442426831873531	0.899129419528398	0.999556182771441
GO:0019787	ubiquitin-like protein transferase activity	8/453	479/18639	0.0167014613778706	0.687193241991456	0.899494275320319	0.999556182771441
GO:0016791	phosphatase activity	4/453	273/18639	0.0146520146520147	0.602867331344152	0.901629535374734	0.999556182771441
GO:0008276	protein methyltransferase activity	1/453	95/18639	0.0105263157894737	0.433112582781457	0.903997047602678	0.999556182771441
GO:0008017	microtubule binding	4/453	276/18639	0.0144927536231884	0.596314425568673	0.906125266528658	0.999556182771441
GO:0004896	cytokine receptor activity	1/453	96/18639	0.0104166666666667	0.428600993377483	0.906342244832832	0.999556182771441
GO:0016407	acetyltransferase activity	1/453	96/18639	0.0104166666666667	0.428600993377483	0.906342244832832	0.999556182771441
GO:0004725	protein tyrosine phosphatase activity	1/453	98/18639	0.0102040816326531	0.419854034328963	0.910862531749196	0.999556182771441
GO:0042626	ATPase-coupled transmembrane transporter activity	1/453	98/18639	0.0102040816326531	0.419854034328963	0.910862531749196	0.999556182771441
GO:0030695	GTPase regulator activity	8/453	489/18639	0.016359918200409	0.673140210457888	0.91097777931835	0.999556182771441
GO:0015081	sodium ion transmembrane transporter activity	2/453	164/18639	0.0121951219512195	0.501776772734615	0.911032319041431	0.999556182771441
GO:0060589	nucleoside-triphosphatase regulator activity	8/453	490/18639	0.0163265306122449	0.671766454926341	0.9120623489891	0.999556182771441
GO:0015103	inorganic anion transmembrane transporter activity	2/453	165/18639	0.0121212121212121	0.498735701384708	0.912784004134533	0.999556182771441
GO:0031267	small GTPase binding	4/453	283/18639	0.0141342756183746	0.581564598787822	0.915915174957547	0.999556182771441
GO:0016874	ligase activity	2/453	167/18639	0.0119760479041916	0.492762818733394	0.916190877968324	0.999556182771441
GO:0003779	actin binding	7/453	443/18639	0.0158013544018059	0.650157714559072	0.916485806443357	0.999556182771441
GO:0008238	exopeptidase activity	1/453	102/18639	0.00980392156862745	0.403389170237631	0.919260444095973	0.999556182771441
GO:0015171	amino acid transmembrane transporter activity	1/453	102/18639	0.00980392156862745	0.403389170237631	0.919260444095973	0.999556182771441
GO:0004722	protein serine/threonine phosphatase activity	1/453	103/18639	0.00970873786407767	0.399472770526586	0.92123352597678	0.999556182771441
GO:0005125	cytokine activity	3/453	234/18639	0.0128205128205128	0.527508914926133	0.926233516329067	0.999556182771441
GO:0000149	SNARE binding	1/453	106/18639	0.00943396226415094	0.388166937398476	0.926868744677652	0.999556182771441
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	5/453	349/18639	0.0143266475644699	0.589479876278487	0.929124969373462	0.999556182771441
GO:0004620	phospholipase activity	1/453	109/18639	0.00917431192660551	0.377483443708609	0.932101626967228	0.999556182771441
GO:1902936	phosphatidylinositol bisphosphate binding	1/453	111/18639	0.00900900900900901	0.370681940218364	0.935380936750599	0.999556182771441
GO:0017124	SH3 domain binding	1/453	115/18639	0.00869565217391304	0.357788655341204	0.941473010105028	0.999556182771441
GO:0042578	phosphoric ester hydrolase activity	5/453	363/18639	0.0137741046831956	0.566745115209895	0.942634675628098	0.999556182771441
GO:0015276	ligand-gated monoatomic ion channel activity	2/453	186/18639	0.010752688172043	0.442426831873531	0.942870130559938	0.999556182771441
GO:0022834	ligand-gated channel activity	2/453	188/18639	0.0106382978723404	0.437720163449345	0.945154075371742	0.999556182771441
GO:0140597	protein carrier chaperone	2/453	188/18639	0.0106382978723404	0.437720163449345	0.945154075371742	0.999556182771441
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/453	122/18639	0.00819672131147541	0.337259798067528	0.950787464779231	0.999556182771441
GO:0022836	gated channel activity	4/453	318/18639	0.0125786163522013	0.517555916531301	0.952438784100514	0.999556182771441
GO:0031072	heat shock protein binding	1/453	131/18639	0.00763358778625954	0.314089277589606	0.960622853602327	0.999556182771441
GO:0005516	calmodulin binding	2/453	207/18639	0.00966183574879227	0.397542950379115	0.962922404124177	0.999556182771441
GO:0004842	ubiquitin-protein transferase activity	6/453	449/18639	0.0133630289532294	0.549831118453075	0.963782391775116	0.999556182771441
GO:0015297	antiporter activity	1/453	135/18639	0.00740740740740741	0.304782928623988	0.964339065880079	0.999556182771441
GO:0140097	catalytic activity, acting on DNA	4/453	336/18639	0.0119047619047619	0.489829706717124	0.964916731234545	0.999556182771441
GO:0140767	enzyme-substrate adaptor activity	1/453	139/18639	0.00719424460431655	0.296012196865025	0.967705261933684	0.999556182771441
GO:0005261	monoatomic cation channel activity	4/453	341/18639	0.0117302052785924	0.482647452952943	0.967800110716756	0.999556182771441
GO:0022843	voltage-gated monoatomic cation channel activity	1/453	143/18639	0.00699300699300699	0.287732135414255	0.970754342461674	0.999556182771441
GO:0015291	secondary active transmembrane transporter activity	3/453	287/18639	0.0104529616724739	0.43009437662967	0.972017210838693	0.999556182771441
GO:0061630	ubiquitin protein ligase activity	4/453	353/18639	0.0113314447592068	0.466240174099019	0.973844541710313	0.999556182771441
GO:0045182	translation regulator activity	4/453	356/18639	0.0112359550561798	0.462311183867847	0.975180325992865	0.999556182771441
GO:0000510	H3-H4 histone complex chaperone activity	1/453	151/18639	0.00662251655629139	0.272488048769791	0.976017616788028	0.999556182771441
GO:0140584	chromatin extrusion motor activity	1/453	151/18639	0.00662251655629139	0.272488048769791	0.976017616788028	0.999556182771441
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	1/453	151/18639	0.00662251655629139	0.272488048769791	0.976017616788028	0.999556182771441
GO:0140849	ATP-dependent H2AZ histone chaperone activity	1/453	151/18639	0.00662251655629139	0.272488048769791	0.976017616788028	0.999556182771441
GO:0015616	DNA translocase activity	1/453	152/18639	0.00657894736842105	0.270695364238411	0.976605242252925	0.999556182771441
GO:0140674	ATP-dependent histone chaperone activity	1/453	152/18639	0.00657894736842105	0.270695364238411	0.976605242252925	0.999556182771441
GO:0061775	cohesin loader activity	1/453	153/18639	0.0065359477124183	0.268926113491754	0.977178500502475	0.999556182771441
GO:0004386	helicase activity	1/453	155/18639	0.00645161290322581	0.265456099124119	0.978283308881245	0.999556182771441
GO:0140375	immune receptor activity	1/453	156/18639	0.00641025641025641	0.263754457463067	0.978815534648222	0.999556182771441
GO:0140658	ATP-dependent chromatin remodeler activity	1/453	158/18639	0.00632911392405063	0.260415793444547	0.979841257197798	0.999556182771441
GO:0003689	DNA clamp loader activity	1/453	160/18639	0.00625	0.25716059602649	0.980817419998867	0.999556182771441
GO:0061659	ubiquitin-like protein ligase activity	4/453	372/18639	0.010752688172043	0.442426831873531	0.981287674236267	0.999556182771441
GO:0140713	histone chaperone activity	1/453	164/18639	0.00609756097560976	0.250888386367307	0.982630509517237	0.999556182771441
GO:0035402	histone H3T11 kinase activity	2/453	247/18639	0.00809716599190283	0.333163525216505	0.984060859703378	0.999556182771441
GO:0005216	monoatomic ion channel activity	5/453	448/18639	0.0111607142857143	0.459215350047304	0.985484023185297	0.999556182771441
GO:0046873	metal ion transmembrane transporter activity	5/453	450/18639	0.0111111111111111	0.457174392935982	0.985968922302441	0.999556182771441
GO:0003823	antigen binding	1/453	174/18639	0.00574712643678161	0.236469513587577	0.986449795073326	0.999556182771441
GO:0030371	translation repressor activity	3/453	329/18639	0.00911854103343465	0.37518871152801	0.987522690656027	0.999556182771441
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1/453	181/18639	0.00552486187845304	0.227324283780323	0.988612672202048	0.999556182771441
GO:0008237	metallopeptidase activity	1/453	184/18639	0.00543478260869565	0.223617909588252	0.989430717681461	0.999556182771441
GO:1901981	phosphatidylinositol phosphate binding	1/453	185/18639	0.00540540540540541	0.222409164131018	0.989690153329811	0.999556182771441
GO:0046943	carboxylic acid transmembrane transporter activity	1/453	188/18639	0.00531914893617021	0.218860081724672	0.990430951044619	0.999556182771441
GO:0005096	GTPase activator activity	2/453	271/18639	0.00738007380073801	0.303658268370763	0.990498439240854	0.999556182771441
GO:0005342	organic acid transmembrane transporter activity	1/453	189/18639	0.00529100529100529	0.217702091874277	0.990665885691889	0.999556182771441
GO:0141003	histone H2AX kinase activity	3/453	354/18639	0.00847457627118644	0.348692333595241	0.992388101742988	0.999556182771441
GO:0140996	histone H3 kinase activity	3/453	357/18639	0.00840336134453781	0.34576214591797	0.992830713489043	0.999556182771441
GO:0035091	phosphatidylinositol binding	2/453	284/18639	0.00704225352112676	0.289758418058017	0.992841052995891	0.999556182771441
GO:0035173	histone kinase activity	3/453	360/18639	0.00833333333333333	0.342880794701987	0.993248420670017	0.999556182771441
GO:0004674	protein serine/threonine kinase activity	4/453	433/18639	0.0092378752886836	0.380098802441001	0.993874565054171	0.999556182771441
GO:0008094	ATP-dependent activity, acting on DNA	1/453	210/18639	0.00476190476190476	0.19593188268685	0.994463602463413	0.999556182771441
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	1/453	229/18639	0.00436681222707424	0.179675525608028	0.996550468262592	0.999556182771441
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	1/453	243/18639	0.00411522633744856	0.169323849235549	0.997566530644776	0.999556182771441
GO:0004676	3-phosphoinositide-dependent protein kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0004711	ribosomal protein S6 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0035175	histone H3S10 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0035979	histone H2AXS139 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0044022	histone H3S28 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0044023	histone H4S1 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0044024	histone H2AS1 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0044025	histone H2BS14 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0072354	histone H3T3 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0072371	histone H2AS121 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0072518	Rho-dependent protein serine/threonine kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0140823	histone H2BS36 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0140855	histone H3S57 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0140995	histone H2A kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0140997	histone H4 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0140998	histone H2B kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:1990244	histone H2AT120 kinase activity	1/453	245/18639	0.00408163265306122	0.167941613731585	0.997684906167847	0.999556182771441
GO:0004677	DNA-dependent protein kinase activity	1/453	246/18639	0.0040650406504065	0.167258924244872	0.997741921363343	0.999556182771441
GO:0140857	histone H3T45 kinase activity	1/453	246/18639	0.0040650406504065	0.167258924244872	0.997741921363343	0.999556182771441
GO:0035403	histone H3T6 kinase activity	1/453	247/18639	0.00404858299595142	0.166581762608253	0.997797535435132	0.999556182771441
GO:0004679	AMP-activated protein kinase activity	1/453	248/18639	0.00403225806451613	0.165910061952574	0.997851782740911	0.999556182771441
GO:0016887	ATP hydrolysis activity	3/453	417/18639	0.00719424460431655	0.296012196865025	0.997887782496665	0.999556182771441
GO:0106310	protein serine kinase activity	2/453	361/18639	0.00554016620498615	0.227953990937609	0.998706297721557	0.999556182771441
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	3/453	484/18639	0.00619834710743802	0.255035301844453	0.999484501480425	0.999556182771441
GO:0001216	DNA-binding transcription activator activity	3/453	491/18639	0.00610997963340122	0.251399360677628	0.999556182771441	0.999556182771441