ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	134/2290	495/18639	0.270707070707071	2.20336641524414	1.50145597455277e-19	1.89033307196194e-16
GO:0042393	histone binding	80/2290	247/18639	0.323886639676113	2.63621095062143	6.48990509194445e-17	4.08539525537903e-14
GO:0003713	transcription coactivator activity	75/2290	256/18639	0.29296875	2.38456093067686	2.2221805673224e-13	9.32575111419633e-11
GO:0140030	modification-dependent protein binding	52/2290	173/18639	0.300578034682081	2.44649519145821	3.76843301273293e-10	1.18611429075769e-07
GO:0003714	transcription corepressor activity	57/2290	204/18639	0.279411764705882	2.2742165425122	1.20766510319835e-09	3.04090072985345e-07
GO:0004674	protein serine/threonine kinase activity	94/2290	433/18639	0.217090069284065	1.76696148532126	1.86126480318236e-08	3.90555397867765e-06
GO:0008094	ATP-dependent activity, acting on DNA	54/2290	210/18639	0.257142857142857	2.09296319401123	7.31357791791888e-08	1.31539922837998e-05
GO:0140033	acetylation-dependent protein binding	13/2290	24/18639	0.541666666666667	4.40878820960699	9.39641744807407e-07	0.000147876119589066
GO:0045296	cadherin binding	72/2290	334/18639	0.215568862275449	1.75457992312319	1.1089516629324e-06	0.000155130015959099
GO:0140097	catalytic activity, acting on DNA	72/2290	336/18639	0.214285714285714	1.74413599500936	1.39852287136311e-06	0.000172518756364267
GO:0140297	DNA-binding transcription factor binding	96/2290	488/18639	0.19672131147541	1.60117402820531	1.63739854056685e-06	0.000172518756364267
GO:0030020	extracellular matrix structural constituent conferring tensile strength	18/2290	44/18639	0.409090909090909	3.32971417229059	1.64434080728451e-06	0.000172518756364267
GO:0140658	ATP-dependent chromatin remodeler activity	41/2290	158/18639	0.259493670886076	2.11209717539108	2.03759404880504e-06	0.000191291224907413
GO:0140034	methylation-dependent protein binding	25/2290	76/18639	0.328947368421053	2.67740174672489	2.17014345734322e-06	0.000191291224907413
GO:0016922	nuclear receptor binding	37/2290	137/18639	0.27007299270073	2.19820546329646	2.27908528483812e-06	0.000191291224907413
GO:0004386	helicase activity	40/2290	155/18639	0.258064516129032	2.10046485420482	3.13278225794959e-06	0.000246510803922409
GO:0070577	lysine-acetylated histone binding	12/2290	23/18639	0.521739130434783	4.24659198784887	4.19741930356862e-06	0.000301112191972581
GO:0005201	extracellular matrix structural constituent	42/2290	168/18639	0.25	2.03482532751092	4.32459038169782e-06	0.000301112191972581
GO:0035064	methylated histone binding	24/2290	74/18639	0.324324324324324	2.639773397852	4.56108994522692e-06	0.000301112191972581
GO:0046332	SMAD binding	25/2290	79/18639	0.316455696202532	2.57572826267205	4.78335491616491e-06	0.000301112191972581
GO:0048407	platelet-derived growth factor binding	8/2290	11/18639	0.727272727272727	5.91949186184994	6.00035391103546e-06	0.000359735503523507
GO:0106310	protein serine kinase activity	73/2290	361/18639	0.202216066481994	1.64589749482878	1.05335077096764e-05	0.000602803918476481
GO:0140463	chromatin-protein adaptor activity	19/2290	54/18639	0.351851851851852	2.86382823871907	1.18415469143275e-05	0.000648195981092973
GO:0015631	tubulin binding	76/2290	385/18639	0.197402597402597	1.60671921964498	1.7025457344925e-05	0.000893127116552524
GO:0140713	histone chaperone activity	39/2290	164/18639	0.23780487804878	1.93556555543721	3.21513451224932e-05	0.00161914174036876
GO:0061775	cohesin loader activity	37/2290	153/18639	0.241830065359477	1.96832776778834	3.43947010963076e-05	0.00166549725693274
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	69/2290	349/18639	0.197707736389685	1.60920283780233	3.87698568668489e-05	0.00180782406649492
GO:0003689	DNA clamp loader activity	38/2290	160/18639	0.2375	1.93308406113537	4.15653623522984e-05	0.00186895682862656
GO:0000510	H3-H4 histone complex chaperone activity	36/2290	151/18639	0.23841059602649	1.9404956765667	6.00299727262554e-05	0.00236180423944861
GO:0140584	chromatin extrusion motor activity	36/2290	151/18639	0.23841059602649	1.9404956765667	6.00299727262554e-05	0.00236180423944861
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	36/2290	151/18639	0.23841059602649	1.9404956765667	6.00299727262554e-05	0.00236180423944861
GO:0140849	ATP-dependent H2AZ histone chaperone activity	36/2290	151/18639	0.23841059602649	1.9404956765667	6.00299727262554e-05	0.00236180423944861
GO:0015616	DNA translocase activity	36/2290	152/18639	0.236842105263158	1.92772925764192	6.94984477215505e-05	0.00257348663768918
GO:0140674	ATP-dependent histone chaperone activity	36/2290	152/18639	0.236842105263158	1.92772925764192	6.94984477215505e-05	0.00257348663768918
GO:0016755	aminoacyltransferase activity	90/2290	496/18639	0.181451612903226	1.47688935061276	8.53843663515094e-05	0.00307139763533001
GO:0016887	ATP hydrolysis activity	78/2290	417/18639	0.18705035971223	1.52245923784989	9.00748922955775e-05	0.00307616827161435
GO:0140938	histone H3 methyltransferase activity	16/2290	47/18639	0.340425531914894	2.77082597788721	9.04036743842183e-05	0.00307616827161435
GO:0019787	ubiquitin-like protein transferase activity	87/2290	479/18639	0.181628392484342	1.47832821288893	0.000107401821666839	0.00355839193364606
GO:0019838	growth factor binding	32/2290	136/18639	0.235294117647059	1.91512972001028	0.000194691083604588	0.00628502754508143
GO:0140996	histone H3 kinase activity	67/2290	357/18639	0.187675070028011	1.52754394334153	0.000247408497392326	0.00778718245542346
GO:0046966	nuclear thyroid hormone receptor binding	11/2290	28/18639	0.392857142857143	3.19758265751716	0.00027220090371061	0.00835855945784532
GO:0035173	histone kinase activity	67/2290	360/18639	0.186111111111111	1.51481441048035	0.00031594987579882	0.00927512725652699
GO:0042054	histone methyltransferase activity	19/2290	67/18639	0.283582089552239	2.30816007299746	0.000322378743483559	0.00927512725652699
GO:0031490	chromatin DNA binding	30/2290	128/18639	0.234375	1.90764874454148	0.000326277772519712	0.00927512725652699
GO:0141003	histone H2AX kinase activity	66/2290	354/18639	0.186440677966102	1.51749685441492	0.00033151765412527	0.00927512725652699
GO:0004842	ubiquitin-protein transferase activity	80/2290	449/18639	0.178173719376392	1.45020958753562	0.000371305803473828	0.0101624784037728
GO:0140857	histone H3T45 kinase activity	49/2290	246/18639	0.199186991869919	1.62124294387049	0.000403069041511369	0.0107971047502726
GO:0019902	phosphatase binding	40/2290	190/18639	0.210526315789474	1.71353711790393	0.000420094062754655	0.011013381326642
GO:0035403	histone H3T6 kinase activity	49/2290	247/18639	0.198380566801619	1.61467920725563	0.000444035561418553	0.011013381326642
GO:0031491	nucleosome binding	20/2290	74/18639	0.27027027027027	2.19981116487667	0.000454998053689514	0.011013381326642
GO:0030332	cyclin binding	12/2290	34/18639	0.352941176470588	2.87269458001541	0.00046417242153094	0.011013381326642
GO:0016279	protein-lysine N-methyltransferase activity	19/2290	69/18639	0.27536231884058	2.24125688247579	0.000485022748851525	0.011013381326642
GO:0004679	AMP-activated protein kinase activity	49/2290	248/18639	0.19758064516129	1.60816840400056	0.00048868781763388	0.011013381326642
GO:0070063	RNA polymerase binding	17/2290	59/18639	0.288135593220339	2.34522241136851	0.000533971290118329	0.011013381326642
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	48/2290	243/18639	0.197530864197531	1.60776322173702	0.000557730031657845	0.011013381326642
GO:0016278	lysine N-methyltransferase activity	19/2290	70/18639	0.271428571428571	2.20923892701185	0.000590117779215131	0.011013381326642
GO:0031625	ubiquitin protein ligase binding	57/2290	302/18639	0.188741721854305	1.53622574394864	0.00059730327722635	0.011013381326642
GO:0140566	histone reader activity	12/2290	35/18639	0.342857142857143	2.79061759201497	0.00062810191511754	0.011013381326642
GO:0008170	N-methyltransferase activity	24/2290	98/18639	0.244897959183673	1.99329828001069	0.00063511048866523	0.011013381326642
GO:0140597	protein carrier chaperone	39/2290	188/18639	0.207446808510638	1.68847208027502	0.000666390728529235	0.011013381326642
GO:0004676	3-phosphoinositide-dependent protein kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0004711	ribosomal protein S6 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0035175	histone H3S10 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0035979	histone H2AXS139 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0044022	histone H3S28 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0044023	histone H4S1 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0044024	histone H2AS1 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0044025	histone H2BS14 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0072354	histone H3T3 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0072371	histone H2AS121 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0072518	Rho-dependent protein serine/threonine kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0140823	histone H2BS36 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0140855	histone H3S57 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0140995	histone H2A kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0140997	histone H4 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0140998	histone H2B kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:1990244	histone H2AT120 kinase activity	48/2290	245/18639	0.195918367346939	1.59463862400856	0.000673574552939981	0.011013381326642
GO:0004677	DNA-dependent protein kinase activity	48/2290	246/18639	0.195121951219512	1.58815635317925	0.000739151646619648	0.0119306656806941
GO:0035402	histone H3T11 kinase activity	48/2290	247/18639	0.194331983805668	1.58172657037286	0.000810335425964644	0.0129140797631581
GO:0097493	structural molecule activity conferring elasticity	6/2290	11/18639	0.545454545454545	4.43961889638746	0.000909545225802721	0.0143139679910703
GO:0008276	protein methyltransferase activity	23/2290	95/18639	0.242105263157895	1.97056768558952	0.000965650066492323	0.0150093016507881
GO:0044389	ubiquitin-like protein ligase binding	59/2290	322/18639	0.183229813664596	1.49136266239931	0.00103424385466384	0.0157982819284041
GO:0016504	peptidase activator activity	16/2290	57/18639	0.280701754385965	2.28471615720524	0.00105233520562012	0.0157982819284041
GO:0008017	microtubule binding	52/2290	276/18639	0.188405797101449	1.53349155116765	0.00105405534708971	0.0157982819284041
GO:0002039	p53 binding	18/2290	69/18639	0.260869565217391	2.12329599392443	0.00134400809825831	0.0199071317142025
GO:0019783	ubiquitin-like protein peptidase activity	28/2290	127/18639	0.220472440944882	1.7944916274112	0.0013961183406622	0.0204385231499268
GO:0070840	dynein complex binding	9/2290	24/18639	0.375	3.05223799126638	0.00145204712039207	0.0210129577537197
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	10/2290	29/18639	0.344827586206897	2.80665562415299	0.00167986602277659	0.0237634980075925
GO:0097472	cyclin-dependent protein kinase activity	10/2290	29/18639	0.344827586206897	2.80665562415299	0.00167986602277659	0.0237634980075925
GO:0001046	core promoter sequence-specific DNA binding	13/2290	44/18639	0.295454545454545	2.40479356887654	0.00182361319283541	0.0255103223308864
GO:0046975	histone H3K36 methyltransferase activity	6/2290	13/18639	0.461538461538462	3.75660060463554	0.00271452459772851	0.0371476790058717
GO:0140666	annealing activity	6/2290	13/18639	0.461538461538462	3.75660060463554	0.00271452459772851	0.0371476790058717
GO:0030695	GTPase regulator activity	81/2290	489/18639	0.165644171779141	1.34822782436306	0.00299564925191002	0.0405540043887604
GO:0060589	nucleoside-triphosphatase regulator activity	81/2290	490/18639	0.16530612244898	1.34547633900722	0.00316726865212634	0.0424211833300751
GO:0005178	integrin binding	32/2290	161/18639	0.198757763975155	1.61774932870433	0.00388681041442132	0.0515104664395415
GO:0002020	protease binding	28/2290	136/18639	0.205882352941176	1.67573850500899	0.00398922942536998	0.0523170817348
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	5/2290	10/18639	0.5	4.06965065502183	0.00411479553910895	0.0528625263646751
GO:0045322	unmethylated CpG binding	5/2290	10/18639	0.5	4.06965065502183	0.00411479553910895	0.0528625263646751
GO:0000149	SNARE binding	23/2290	106/18639	0.216981132075472	1.76607481255665	0.00439474476883648	0.0551593694508212
GO:0004197	cysteine-type endopeptidase activity	20/2290	88/18639	0.227272727272727	1.84984120682811	0.00440240975093461	0.0551593694508212
GO:0043130	ubiquitin binding	22/2290	100/18639	0.22	1.79064628820961	0.00442501692973228	0.0551593694508212
GO:0036408	histone H3K14 acetyltransferase activity	9/2290	28/18639	0.321428571428571	2.61620399251404	0.00486370087151982	0.0600333274239555
GO:0140104	molecular carrier activity	45/2290	249/18639	0.180722891566265	1.47095806808018	0.00495514321861048	0.0605682069148601
GO:0001098	basal transcription machinery binding	15/2290	60/18639	0.25	2.03482532751092	0.00506568024830002	0.0607399184058069
GO:0001099	basal RNA polymerase II transcription machinery binding	15/2290	60/18639	0.25	2.03482532751092	0.00506568024830002	0.0607399184058069
GO:0032182	ubiquitin-like protein binding	25/2290	120/18639	0.208333333333333	1.69568777292576	0.00536458935182685	0.0637171508863208
GO:0140036	ubiquitin-modified protein reader activity	7/2290	19/18639	0.368421052631579	2.99868995633188	0.00550231054345871	0.0639688838689569
GO:1990380	K48-linked deubiquitinase activity	7/2290	19/18639	0.368421052631579	2.99868995633188	0.00550231054345871	0.0639688838689569
GO:0001223	transcription coactivator binding	12/2290	44/18639	0.272727272727273	2.21980944819373	0.00555248221075579	0.0639688838689569
GO:0004843	cysteine-type deubiquitinase activity	23/2290	108/18639	0.212962962962963	1.73336972343523	0.00558902083048868	0.0639688838689569
GO:0050431	transforming growth factor beta binding	8/2290	24/18639	0.333333333333333	2.71310043668122	0.00611751130964863	0.0690673294311315
GO:0101005	deubiquitinase activity	24/2290	115/18639	0.208695652173913	1.69863679513955	0.00614419451651051	0.0690673294311315
GO:0010484	histone H3 acetyltransferase activity	9/2290	29/18639	0.310344827586207	2.52599006173769	0.00629642655345428	0.070152221511495
GO:0042809	nuclear vitamin D receptor binding	6/2290	15/18639	0.4	3.25572052401747	0.00636986785261889	0.0703479265477823
GO:0008186	ATP-dependent activity, acting on RNA	18/2290	79/18639	0.227848101265823	1.85452434912387	0.00650585399947573	0.0712249581333908
GO:0008172	S-methyltransferase activity	5/2290	11/18639	0.454545454545455	3.69968241365621	0.00678583746686415	0.0730101722920664
GO:0034056	estrogen response element binding	5/2290	11/18639	0.454545454545455	3.69968241365621	0.00678583746686415	0.0730101722920664
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	32/2290	167/18639	0.191616766467066	1.55962659833172	0.00684289144596015	0.0730101722920664
GO:0003684	damaged DNA binding	17/2290	74/18639	0.22972972972973	1.86983949014517	0.00738593253305975	0.0781419248665733
GO:0016505	peptidase activator activity involved in apoptotic process	7/2290	20/18639	0.35	2.84875545851528	0.00758025165866518	0.0788722052748716
GO:0043024	ribosomal small subunit binding	7/2290	20/18639	0.35	2.84875545851528	0.00758025165866518	0.0788722052748716
GO:0019208	phosphatase regulator activity	24/2290	117/18639	0.205128205128205	1.66960026872691	0.00765787104822068	0.0790267184402445
GO:0010485	histone H4 acetyltransferase activity	10/2290	35/18639	0.285714285714286	2.32551466001248	0.00773603547994254	0.0791190763494398
GO:0001965	G-protein alpha-subunit binding	9/2290	30/18639	0.3	2.4417903930131	0.00803244751542793	0.0791190763494398
GO:0043995	histone H4K5 acetyltransferase activity	9/2290	30/18639	0.3	2.4417903930131	0.00803244751542793	0.0791190763494398
GO:0043996	histone H4K8 acetyltransferase activity	9/2290	30/18639	0.3	2.4417903930131	0.00803244751542793	0.0791190763494398
GO:0043997	histone H4K12 acetyltransferase activity	9/2290	30/18639	0.3	2.4417903930131	0.00803244751542793	0.0791190763494398
GO:0042974	nuclear retinoic acid receptor binding	8/2290	25/18639	0.32	2.60457641921397	0.00804387750018133	0.0791190763494398
GO:0019903	protein phosphatase binding	28/2290	144/18639	0.194444444444444	1.58264192139738	0.00894356322800286	0.0872864039074077
GO:0005096	GTPase activator activity	47/2290	271/18639	0.173431734317343	1.4116131423323	0.00902811991406785	0.087433869013934
GO:0005159	insulin-like growth factor receptor binding	6/2290	16/18639	0.375	3.05223799126638	0.00914620771928668	0.0879013398365032
GO:0061733	protein-lysine-acetyltransferase activity	12/2290	47/18639	0.25531914893617	2.0781194834154	0.00971781974445449	0.0902713498783005
GO:0061749	forked DNA-dependent helicase activity	12/2290	47/18639	0.25531914893617	2.0781194834154	0.00971781974445449	0.0902713498783005
GO:1990518	single-stranded 3'-5' DNA helicase activity	12/2290	47/18639	0.25531914893617	2.0781194834154	0.00971781974445449	0.0902713498783005
GO:0070325	lipoprotein particle receptor binding	9/2290	31/18639	0.290322580645161	2.36302296098042	0.0101095766367553	0.0902713498783005
GO:0050681	nuclear androgen receptor binding	8/2290	26/18639	0.307692307692308	2.50440040309036	0.0103913797254911	0.0902713498783005
GO:0050750	low-density lipoprotein particle receptor binding	8/2290	26/18639	0.307692307692308	2.50440040309036	0.0103913797254911	0.0902713498783005
GO:0017166	vinculin binding	5/2290	12/18639	0.416666666666667	3.39137554585153	0.0104683217491913	0.0902713498783005
GO:0031543	peptidyl-proline dioxygenase activity	5/2290	12/18639	0.416666666666667	3.39137554585153	0.0104683217491913	0.0902713498783005
GO:0035259	nuclear glucocorticoid receptor binding	5/2290	12/18639	0.416666666666667	3.39137554585153	0.0104683217491913	0.0902713498783005
GO:0035497	cAMP response element binding	5/2290	12/18639	0.416666666666667	3.39137554585153	0.0104683217491913	0.0902713498783005
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	5/2290	12/18639	0.416666666666667	3.39137554585153	0.0104683217491913	0.0902713498783005
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	5/2290	12/18639	0.416666666666667	3.39137554585153	0.0104683217491913	0.0902713498783005
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	5/2290	12/18639	0.416666666666667	3.39137554585153	0.0104683217491913	0.0902713498783005
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	5/2290	12/18639	0.416666666666667	3.39137554585153	0.0104683217491913	0.0902713498783005
GO:1990247	N6-methyladenosine-containing RNA reader activity	5/2290	12/18639	0.416666666666667	3.39137554585153	0.0104683217491913	0.0902713498783005
GO:0004402	histone acetyltransferase activity	11/2290	42/18639	0.261904761904762	2.1317217716781	0.0107108801035005	0.0911148516912644
GO:0043175	RNA polymerase core enzyme binding	11/2290	42/18639	0.261904761904762	2.1317217716781	0.0107108801035005	0.0911148516912644
GO:0003727	single-stranded RNA binding	19/2290	89/18639	0.213483146067416	1.73760365045876	0.010824542428694	0.0914637511256758
GO:0003724	RNA helicase activity	17/2290	77/18639	0.220779220779221	1.79698860091873	0.011071011263595	0.0929226878724409
GO:0009378	four-way junction helicase activity	12/2290	48/18639	0.25	2.03482532751092	0.0115434807214936	0.0943717027815611
GO:0036121	double-stranded DNA helicase activity	12/2290	48/18639	0.25	2.03482532751092	0.0115434807214936	0.0943717027815611
GO:0043138	3'-5' DNA helicase activity	12/2290	48/18639	0.25	2.03482532751092	0.0115434807214936	0.0943717027815611
GO:0140693	molecular condensate scaffold activity	12/2290	48/18639	0.25	2.03482532751092	0.0115434807214936	0.0943717027815611
GO:0001221	transcription coregulator binding	23/2290	115/18639	0.2	1.62786026200873	0.0120487851436006	0.0971869224140277
GO:0017124	SH3 domain binding	23/2290	115/18639	0.2	1.62786026200873	0.0120487851436006	0.0971869224140277
GO:0008234	cysteine-type peptidase activity	34/2290	187/18639	0.181818181818182	1.47987296546249	0.0121194176481353	0.0971869224140277
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	14/2290	60/18639	0.233333333333333	1.89917030567686	0.0124550298603072	0.0980107963605889
GO:0070717	poly-purine tract binding	9/2290	32/18639	0.28125	2.28917849344978	0.0125660046856573	0.0980107963605889
GO:0005518	collagen binding	16/2290	72/18639	0.222222222222222	1.80873362445415	0.0126579828845748	0.0980107963605889
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/2290	17/18639	0.352941176470588	2.87269458001541	0.012689245279409	0.0980107963605889
GO:0015278	intracellularly gated calcium channel activity	6/2290	17/18639	0.352941176470588	2.87269458001541	0.012689245279409	0.0980107963605889
GO:0046965	nuclear retinoid X receptor binding	6/2290	17/18639	0.352941176470588	2.87269458001541	0.012689245279409	0.0980107963605889
GO:0140035	ubiquitin-like protein reader activity	7/2290	22/18639	0.318181818181818	2.58977768955935	0.0133839332083805	0.102123466117279
GO:0140517	protein-RNA adaptor activity	7/2290	22/18639	0.318181818181818	2.58977768955935	0.0133839332083805	0.102123466117279
GO:0019905	syntaxin binding	14/2290	61/18639	0.229508196721311	1.86803636623953	0.0143864714835352	0.109096303244108
GO:0050840	extracellular matrix binding	15/2290	67/18639	0.223880597014925	1.82223163657694	0.014471074377892	0.109096303244108
GO:0097157	pre-mRNA intronic binding	5/2290	13/18639	0.384615384615385	3.13050050386295	0.0153144449688556	0.113416977739936
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	5/2290	13/18639	0.384615384615385	3.13050050386295	0.0153144449688556	0.113416977739936
GO:0140852	histone ubiquitin ligase activity	5/2290	13/18639	0.384615384615385	3.13050050386295	0.0153144449688556	0.113416977739936
GO:0008168	methyltransferase activity	36/2290	204/18639	0.176470588235294	1.43634729000771	0.0157717109571578	0.116120374824922
GO:0061659	ubiquitin-like protein ligase activity	60/2290	372/18639	0.161290322580645	1.31279053387801	0.0163206466128864	0.118999034573969
GO:0003678	DNA helicase activity	16/2290	74/18639	0.216216216216216	1.75984893190133	0.0163517339009505	0.118999034573969
GO:0008409	5'-3' exonuclease activity	6/2290	18/18639	0.333333333333333	2.71310043668122	0.0170929277972811	0.122971406267297
GO:1990381	ubiquitin-specific protease binding	6/2290	18/18639	0.333333333333333	2.71310043668122	0.0170929277972811	0.122971406267297
GO:0017134	fibroblast growth factor binding	7/2290	23/18639	0.304347826086957	2.47717865957851	0.0172433729833423	0.123348901056977
GO:0008201	heparin binding	31/2290	172/18639	0.180232558139535	1.46696709657764	0.0180165124160468	0.127500576953977
GO:1901681	sulfur compound binding	46/2290	275/18639	0.167272727272727	1.36148312822549	0.0180262928497283	0.127500576953977
GO:0061630	ubiquitin protein ligase activity	57/2290	353/18639	0.161473087818697	1.31427811521952	0.0184469108505802	0.129746708161344
GO:0031267	small GTPase binding	47/2290	283/18639	0.166077738515901	1.35175675467156	0.0191261906699458	0.133777078074787
GO:0019888	protein phosphatase regulator activity	21/2290	107/18639	0.196261682242991	1.59743296739175	0.0194768928237038	0.135477392624547
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	75/2290	484/18639	0.15495867768595	1.26125536829189	0.0197856849748584	0.136869106501905
GO:0035091	phosphatidylinositol binding	47/2290	284/18639	0.165492957746479	1.34699704778892	0.0202702889130457	0.139455157057511
GO:0106222	lncRNA binding	8/2290	29/18639	0.275862068965517	2.24532449932239	0.0204538981145103	0.139953574598741
GO:0016741	transferase activity, transferring one-carbon groups	37/2290	215/18639	0.172093023255814	1.40071696963542	0.0210224730222229	0.142924213444425
GO:0030276	clathrin binding	11/2290	46/18639	0.239130434782609	1.9463546610974	0.0211257422175807	0.142924213444425
GO:0005161	platelet-derived growth factor receptor binding	5/2290	14/18639	0.357142857142857	2.9068933250156	0.0214556603185038	0.142924213444425
GO:0008195	phosphatidate phosphatase activity	5/2290	14/18639	0.357142857142857	2.9068933250156	0.0214556603185038	0.142924213444425
GO:0030983	mismatched DNA binding	5/2290	14/18639	0.357142857142857	2.9068933250156	0.0214556603185038	0.142924213444425
GO:0042577	lipid phosphatase activity	6/2290	19/18639	0.315789473684211	2.5703056768559	0.0224424434528915	0.148710717406265
GO:0019207	kinase regulator activity	47/2290	287/18639	0.163763066202091	1.33291693927544	0.0240352351730502	0.158431209857959
GO:0031593	polyubiquitin modification-dependent protein binding	13/2290	59/18639	0.220338983050847	1.79340537339945	0.0247999276362093	0.161221659769152
GO:0034212	protein N-acetyltransferase activity	12/2290	53/18639	0.226415094339623	1.84286067397215	0.0248709504622501	0.161221659769152
GO:0140296	general transcription initiation factor binding	12/2290	53/18639	0.226415094339623	1.84286067397215	0.0248709504622501	0.161221659769152
GO:0032452	histone demethylase activity	8/2290	30/18639	0.266666666666667	2.17048034934498	0.0249707892414493	0.161221659769152
GO:0005543	phospholipid binding	76/2290	497/18639	0.152917505030181	1.24464164902076	0.0252578156242992	0.162113896195453
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/2290	10/18639	0.4	3.25572052401747	0.0258815672242146	0.162113896195453
GO:0035374	chondroitin sulfate binding	4/2290	10/18639	0.4	3.25572052401747	0.0258815672242146	0.162113896195453
GO:0042975	peroxisome proliferator activated receptor binding	4/2290	10/18639	0.4	3.25572052401747	0.0258815672242146	0.162113896195453
GO:0051880	G-quadruplex DNA binding	4/2290	10/18639	0.4	3.25572052401747	0.0258815672242146	0.162113896195453
GO:1905394	retromer complex binding	4/2290	10/18639	0.4	3.25572052401747	0.0258815672242146	0.162113896195453
GO:0043021	ribonucleoprotein complex binding	31/2290	177/18639	0.175141242937853	1.42552734808674	0.0260793953882875	0.162544350464624
GO:0001216	DNA-binding transcription activator activity	75/2290	491/18639	0.152749490835031	1.24327413086207	0.0266819677027329	0.165335188364178
GO:0000993	RNA polymerase II complex binding	9/2290	36/18639	0.25	2.03482532751092	0.0269300929020641	0.165335188364178
GO:0005484	SNAP receptor activity	9/2290	36/18639	0.25	2.03482532751092	0.0269300929020641	0.165335188364178
GO:0019211	phosphatase activator activity	7/2290	25/18639	0.28	2.27900436681223	0.0271837839486773	0.165335188364178
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	7/2290	25/18639	0.28	2.27900436681223	0.0271837839486773	0.165335188364178
GO:0035198	miRNA binding	10/2290	42/18639	0.238095238095238	1.93792888334373	0.0280255088467009	0.169635171336521
GO:0031418	L-ascorbic acid binding	6/2290	20/18639	0.3	2.4417903930131	0.0288119542218456	0.17221312593524
GO:0140939	histone H4 methyltransferase activity	6/2290	20/18639	0.3	2.4417903930131	0.0288119542218456	0.17221312593524
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	5/2290	15/18639	0.333333333333333	2.71310043668122	0.0289985565514463	0.17221312593524
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	5/2290	15/18639	0.333333333333333	2.71310043668122	0.0289985565514463	0.17221312593524
GO:0140457	protein demethylase activity	8/2290	31/18639	0.258064516129032	2.10046485420482	0.0301399066691689	0.17815090373936
GO:0005539	glycosaminoglycan binding	40/2290	242/18639	0.165289256198347	1.34533905951135	0.0307851355263193	0.181114418820729
GO:0001222	transcription corepressor binding	11/2290	49/18639	0.224489795918367	1.8271900900098	0.032802469805474	0.191705269746746
GO:0051213	dioxygenase activity	18/2290	93/18639	0.193548387096774	1.57534864065361	0.0328898635943583	0.191705269746746
GO:0008143	poly(A) binding	7/2290	26/18639	0.269230769230769	2.19135035270406	0.0333704591887986	0.192722055590355
GO:0034237	protein kinase A regulatory subunit binding	7/2290	26/18639	0.269230769230769	2.19135035270406	0.0333704591887986	0.192722055590355
GO:0051020	GTPase binding	50/2290	315/18639	0.158730158730159	1.29195258889582	0.0341085913576212	0.196085463558197
GO:0004713	protein tyrosine kinase activity	25/2290	140/18639	0.178571428571429	1.4534466625078	0.0344302918677782	0.197035170279694
GO:1990841	promoter-specific chromatin binding	14/2290	68/18639	0.205882352941176	1.67573850500899	0.0349680839973831	0.199207320147988
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/2290	11/18639	0.363636363636364	2.95974593092497	0.0367934127998434	0.20772603908073
GO:0004143	ATP-dependent diacylglycerol kinase activity	4/2290	11/18639	0.363636363636364	2.95974593092497	0.0367934127998434	0.20772603908073
GO:0003725	double-stranded RNA binding	15/2290	75/18639	0.2	1.62786026200873	0.0375820732745833	0.209956756610616
GO:0019209	kinase activator activity	26/2290	148/18639	0.175675675675676	1.42987725716983	0.0376803825827157	0.209956756610616
GO:0000062	fatty-acyl-CoA binding	5/2290	16/18639	0.3125	2.54353165938865	0.0380223514751552	0.209956756610616
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/2290	16/18639	0.3125	2.54353165938865	0.0380223514751552	0.209956756610616
GO:0005024	transforming growth factor beta receptor activity	5/2290	16/18639	0.3125	2.54353165938865	0.0380223514751552	0.209956756610616
GO:0008080	N-acetyltransferase activity	14/2290	69/18639	0.202898550724638	1.65145243971901	0.0390890166052301	0.214904244130938
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	43/2290	268/18639	0.16044776119403	1.30593267288014	0.0400259371707827	0.219098499556589
GO:0035255	ionotropic glutamate receptor binding	7/2290	27/18639	0.259259259259259	2.11018922852984	0.0404266526381368	0.22033400723556
GO:0003743	translation initiation factor activity	11/2290	51/18639	0.215686274509804	1.75553557667609	0.042755199033972	0.226733374859598
GO:0019887	protein kinase regulator activity	41/2290	255/18639	0.16078431372549	1.30867197534035	0.0428200206573782	0.226733374859598
GO:0000217	DNA secondary structure binding	9/2290	39/18639	0.230769230769231	1.87830030231777	0.0434095205781343	0.226733374859598
GO:0008135	translation factor activity, RNA binding	16/2290	83/18639	0.192771084337349	1.56902193928553	0.0439401779373128	0.226733374859598
GO:0032931	histone H3K56 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0043992	histone H3K9 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0043993	histone H3K18 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0043994	histone H3K23 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0043999	histone H2AK5 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0044012	histone H2AK9 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0044014	histone H2BK5 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0044015	histone H2BK12 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0044016	histone H3K4 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0044017	histone H3K27 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0044018	histone H3K36 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0046972	histone H4K16 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0050321	tau-protein kinase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0140908	histone H3K122 acetyltransferase activity	6/2290	22/18639	0.272727272727273	2.21980944819373	0.0448424228276726	0.226733374859598
GO:0001217	DNA-binding transcription repressor activity	44/2290	278/18639	0.158273381294964	1.28823473971914	0.0462897937248495	0.233115401198342
GO:0017116	single-stranded DNA helicase activity	12/2290	58/18639	0.206896551724138	1.68399337449179	0.0469855097614112	0.234741098371495
GO:0061980	regulatory RNA binding	12/2290	58/18639	0.206896551724138	1.68399337449179	0.0469855097614112	0.234741098371495
GO:0180051	translation factor activity	16/2290	84/18639	0.19047619047619	1.55034310667498	0.0483291004123109	0.238894380770256
GO:0045499	chemorepellent activity	7/2290	28/18639	0.25	2.03482532751092	0.0483860739447302	0.238894380770256
GO:0141052	histone H3 demethylase activity	7/2290	28/18639	0.25	2.03482532751092	0.0483860739447302	0.238894380770256
GO:1901567	fatty acid derivative binding	5/2290	17/18639	0.294117647058824	2.39391215001284	0.0485778123900494	0.238904163277626
GO:0005165	neurotrophin receptor binding	4/2290	12/18639	0.333333333333333	2.71310043668122	0.0499559583251695	0.241902121274571
GO:0034452	dynactin binding	4/2290	12/18639	0.333333333333333	2.71310043668122	0.0499559583251695	0.241902121274571
GO:0035197	siRNA binding	4/2290	12/18639	0.333333333333333	2.71310043668122	0.0499559583251695	0.241902121274571
GO:0070410	co-SMAD binding	4/2290	12/18639	0.333333333333333	2.71310043668122	0.0499559583251695	0.241902121274571
GO:0019199	transmembrane receptor protein kinase activity	15/2290	78/18639	0.192307692307692	1.56525025193147	0.050887194282229	0.245467347131519
GO:0030295	protein kinase activator activity	24/2290	139/18639	0.172661870503597	1.40534698878452	0.0527600944769424	0.253530377658284
GO:0044013	histone H2B acetyltransferase activity	6/2290	23/18639	0.260869565217391	2.12329599392443	0.054583263949201	0.260427166256899
GO:0051018	protein kinase A binding	11/2290	53/18639	0.207547169811321	1.68928895114114	0.0546090324796039	0.260427166256899
GO:0001727	lipid kinase activity	9/2290	41/18639	0.219512195121951	1.78667589732666	0.0575157905947647	0.27120741707419
GO:0008137	NADH dehydrogenase (ubiquinone) activity	9/2290	41/18639	0.219512195121951	1.78667589732666	0.0575157905947647	0.27120741707419
GO:0061650	ubiquitin-like protein conjugating enzyme activity	9/2290	41/18639	0.219512195121951	1.78667589732666	0.0575157905947647	0.27120741707419
GO:0043015	gamma-tubulin binding	8/2290	35/18639	0.228571428571429	1.86041172800998	0.0579956014628619	0.272449485976653
GO:0051219	phosphoprotein binding	17/2290	93/18639	0.182795698924731	1.48782927172841	0.0596908657334697	0.27783787521662
GO:0042826	histone deacetylase binding	22/2290	127/18639	0.173228346456693	1.40995770725166	0.0597899453800373	0.27783787521662
GO:0000400	four-way junction DNA binding	5/2290	18/18639	0.277777777777778	2.26091703056769	0.0606873833872681	0.27783787521662
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	5/2290	18/18639	0.277777777777778	2.26091703056769	0.0606873833872681	0.27783787521662
GO:0015172	acidic amino acid transmembrane transporter activity	5/2290	18/18639	0.277777777777778	2.26091703056769	0.0606873833872681	0.27783787521662
GO:0031690	adrenergic receptor binding	5/2290	18/18639	0.277777777777778	2.26091703056769	0.0606873833872681	0.27783787521662
GO:0035615	clathrin adaptor activity	5/2290	18/18639	0.277777777777778	2.26091703056769	0.0606873833872681	0.27783787521662
GO:0046974	histone H3K9 methyltransferase activity	4/2290	13/18639	0.307692307692308	2.50440040309036	0.0653521864835312	0.292688903323447
GO:0051011	microtubule minus-end binding	4/2290	13/18639	0.307692307692308	2.50440040309036	0.0653521864835312	0.292688903323447
GO:0001091	RNA polymerase II general transcription initiation factor binding	6/2290	24/18639	0.25	2.03482532751092	0.0655028152179018	0.292688903323447
GO:0035035	histone acetyltransferase binding	6/2290	24/18639	0.25	2.03482532751092	0.0655028152179018	0.292688903323447
GO:0043998	histone H2A acetyltransferase activity	6/2290	24/18639	0.25	2.03482532751092	0.0655028152179018	0.292688903323447
GO:0031492	nucleosomal DNA binding	9/2290	42/18639	0.214285714285714	1.74413599500936	0.065558594707873	0.292688903323447
GO:0048487	beta-tubulin binding	9/2290	42/18639	0.214285714285714	1.74413599500936	0.065558594707873	0.292688903323447
GO:0031624	ubiquitin conjugating enzyme binding	7/2290	30/18639	0.233333333333333	1.89917030567686	0.0671048699302075	0.297482504373702
GO:0098918	structural constituent of synapse	7/2290	30/18639	0.233333333333333	1.89917030567686	0.0671048699302075	0.297482504373702
GO:0044325	transmembrane transporter binding	23/2290	136/18639	0.169117647058824	1.37649948625739	0.0689886664633189	0.304760459920416
GO:0003779	actin binding	65/2290	443/18639	0.146726862302483	1.1942541425572	0.0725601552797038	0.319416907332682
GO:0042800	histone H3K4 methyltransferase activity	5/2290	19/18639	0.263157894736842	2.14192139737991	0.0743462905066883	0.325006874124724
GO:0120227	acyl-CoA binding	5/2290	19/18639	0.263157894736842	2.14192139737991	0.0743462905066883	0.325006874124724
GO:0016407	acetyltransferase activity	17/2290	96/18639	0.177083333333333	1.4413346069869	0.0761654926822064	0.331807457740131
GO:0051015	actin filament binding	33/2290	209/18639	0.157894736842105	1.28515283842795	0.0775891338313956	0.336843860323197
GO:0017147	Wnt-protein binding	7/2290	31/18639	0.225806451612903	1.83790674742922	0.0778863175480102	0.336972074889845
GO:0008331	high voltage-gated calcium channel activity	4/2290	14/18639	0.285714285714286	2.32551466001248	0.0829107969495423	0.355049977413176
GO:0032454	histone H3K9 demethylase activity	4/2290	14/18639	0.285714285714286	2.32551466001248	0.0829107969495423	0.355049977413176
GO:0042813	Wnt receptor activity	4/2290	14/18639	0.285714285714286	2.32551466001248	0.0829107969495423	0.355049977413176
GO:1902936	phosphatidylinositol bisphosphate binding	19/2290	111/18639	0.171171171171171	1.39321373775522	0.0835470363349914	0.355882955049819
GO:0003954	NADH dehydrogenase activity	9/2290	44/18639	0.204545454545455	1.6648570861453	0.0836706550395126	0.355882955049819
GO:0051117	ATPase binding	15/2290	84/18639	0.178571428571429	1.4534466625078	0.0865664498787696	0.366960136018084
GO:0042162	telomeric DNA binding	8/2290	38/18639	0.210526315789474	1.71353711790393	0.0869978824652278	0.367551456455442
GO:0005200	structural constituent of cytoskeleton	19/2290	112/18639	0.169642857142857	1.38077432938241	0.089567444563856	0.374835175792508
GO:0043022	ribosome binding	19/2290	112/18639	0.169642857142857	1.38077432938241	0.089567444563856	0.374835175792508
GO:0043425	bHLH transcription factor binding	7/2290	32/18639	0.21875	1.78047216157205	0.0896150817422915	0.374835175792508
GO:0005160	transforming growth factor beta receptor binding	6/2290	26/18639	0.230769230769231	1.87830030231777	0.0908734927582093	0.376347787442715
GO:0030507	spectrin binding	6/2290	26/18639	0.230769230769231	1.87830030231777	0.0908734927582093	0.376347787442715
GO:0070412	R-SMAD binding	6/2290	26/18639	0.230769230769231	1.87830030231777	0.0908734927582093	0.376347787442715
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	11/2290	58/18639	0.189655172413793	1.54366059328414	0.0931681730947184	0.384585999758198
GO:1901981	phosphatidylinositol phosphate binding	29/2290	185/18639	0.156756756756757	1.27589047562847	0.0997290415983837	0.410323082916226
GO:0030296	protein tyrosine kinase activator activity	7/2290	33/18639	0.212121212121212	1.72651845970623	0.102279321202706	0.416344184633144
GO:0071889	14-3-3 protein binding	7/2290	33/18639	0.212121212121212	1.72651845970623	0.102279321202706	0.416344184633144
GO:0036002	pre-mRNA binding	11/2290	59/18639	0.186440677966102	1.51749685441492	0.102453607537446	0.416344184633144
GO:0061578	K63-linked deubiquitinase activity	4/2290	15/18639	0.266666666666667	2.17048034934498	0.102515248003395	0.416344184633144
GO:0008266	poly(U) RNA binding	6/2290	27/18639	0.222222222222222	1.80873362445415	0.105286875649658	0.419016680179348
GO:0005085	guanyl-nucleotide exchange factor activity	35/2290	230/18639	0.152173913043478	1.23858932978925	0.105778359497615	0.419016680179348
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/2290	21/18639	0.238095238095238	1.93792888334373	0.106168642555371	0.419016680179348
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/2290	21/18639	0.238095238095238	1.93792888334373	0.106168642555371	0.419016680179348
GO:0010314	phosphatidylinositol-5-phosphate binding	5/2290	21/18639	0.238095238095238	1.93792888334373	0.106168642555371	0.419016680179348
GO:0051010	microtubule plus-end binding	5/2290	21/18639	0.238095238095238	1.93792888334373	0.106168642555371	0.419016680179348
GO:0061891	calcium ion sensor activity	5/2290	21/18639	0.238095238095238	1.93792888334373	0.106168642555371	0.419016680179348
GO:0072542	protein phosphatase activator activity	5/2290	21/18639	0.238095238095238	1.93792888334373	0.106168642555371	0.419016680179348
GO:0140312	cargo adaptor activity	5/2290	21/18639	0.238095238095238	1.93792888334373	0.106168642555371	0.419016680179348
GO:0043539	protein serine/threonine kinase activator activity	13/2290	73/18639	0.178082191780822	1.44946461685709	0.107080432832032	0.421294577923527
GO:0035401	histone H3Y41 kinase activity	19/2290	115/18639	0.165217391304348	1.34475412948548	0.109274362621017	0.427183630982002
GO:0140801	histone H2AXY142 kinase activity	19/2290	115/18639	0.165217391304348	1.34475412948548	0.109274362621017	0.427183630982002
GO:0030331	nuclear estrogen receptor binding	8/2290	40/18639	0.2	1.62786026200873	0.110273772890509	0.427183630982002
GO:0032451	demethylase activity	8/2290	40/18639	0.2	1.62786026200873	0.110273772890509	0.427183630982002
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	8/2290	40/18639	0.2	1.62786026200873	0.110273772890509	0.427183630982002
GO:0004090	carbonyl reductase (NADPH) activity	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:0005522	profilin binding	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:0015643	toxic substance binding	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:0016868	intramolecular phosphotransferase activity	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:0019911	structural constituent of myelin sheath	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:0050815	phosphoserine residue binding	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:0140999	histone H3K4 trimethyltransferase activity	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:1990757	ubiquitin ligase activator activity	3/2290	10/18639	0.3	2.4417903930131	0.114765157617039	0.431311443104036
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	28/2290	181/18639	0.154696132596685	1.25911843470289	0.117493730610132	0.438951625158735
GO:0016651	oxidoreductase activity, acting on NAD(P)H	15/2290	88/18639	0.170454545454545	1.38738090512108	0.117495391325253	0.438951625158735
GO:0019789	SUMO transferase activity	6/2290	28/18639	0.214285714285714	1.74413599500936	0.120805276114639	0.448654403033422
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	6/2290	28/18639	0.214285714285714	1.74413599500936	0.120805276114639	0.448654403033422
GO:0042169	SH2 domain binding	8/2290	41/18639	0.195121951219512	1.58815635317925	0.123063586780386	0.453919158106628
GO:0016722	oxidoreductase activity, acting on metal ions	4/2290	16/18639	0.25	2.03482532751092	0.124012880179475	0.453919158106628
GO:0034450	ubiquitin-ubiquitin ligase activity	4/2290	16/18639	0.25	2.03482532751092	0.124012880179475	0.453919158106628
GO:0070411	I-SMAD binding	4/2290	16/18639	0.25	2.03482532751092	0.124012880179475	0.453919158106628
GO:0140784	metal ion sensor activity	5/2290	22/18639	0.227272727272727	1.84984120682811	0.124205766004694	0.453919158106628
GO:0003777	microtubule motor activity	12/2290	68/18639	0.176470588235294	1.43634729000771	0.124386107662261	0.453919158106628
GO:0019003	GDP binding	13/2290	75/18639	0.173333333333333	1.41081222707424	0.12547566058369	0.456571840100767
GO:0016247	channel regulator activity	26/2290	168/18639	0.154761904761905	1.25965377417342	0.127088423213144	0.461107564338178
GO:0061631	ubiquitin conjugating enzyme activity	7/2290	35/18639	0.2	1.62786026200873	0.130324331988496	0.471489465441141
GO:0001540	amyloid-beta binding	14/2290	83/18639	0.168674698795181	1.37289419687484	0.135407151714222	0.488474510052166
GO:0099604	ligand-gated calcium channel activity	6/2290	29/18639	0.206896551724138	1.68399337449179	0.137378760900328	0.49417102849575
GO:0141108	transporter regulator activity	26/2290	170/18639	0.152941176470588	1.24483431800668	0.140157609045939	0.49671710537444
GO:0035254	glutamate receptor binding	9/2290	49/18639	0.183673469387755	1.49497371000802	0.14068951816673	0.49671710537444
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	5/2290	23/18639	0.217391304347826	1.76941332827036	0.143545349908997	0.49671710537444
GO:0042171	lysophosphatidic acid acyltransferase activity	5/2290	23/18639	0.217391304347826	1.76941332827036	0.143545349908997	0.49671710537444
GO:0071617	lysophospholipid acyltransferase activity	5/2290	23/18639	0.217391304347826	1.76941332827036	0.143545349908997	0.49671710537444
GO:0099186	structural constituent of postsynapse	5/2290	23/18639	0.217391304347826	1.76941332827036	0.143545349908997	0.49671710537444
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	5/2290	23/18639	0.217391304347826	1.76941332827036	0.143545349908997	0.49671710537444
GO:0000099	sulfur amino acid transmembrane transporter activity	3/2290	11/18639	0.272727272727273	2.21980944819373	0.144004561923487	0.49671710537444
GO:0005114	type II transforming growth factor beta receptor binding	3/2290	11/18639	0.272727272727273	2.21980944819373	0.144004561923487	0.49671710537444
GO:0010854	adenylate cyclase regulator activity	3/2290	11/18639	0.272727272727273	2.21980944819373	0.144004561923487	0.49671710537444
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/2290	11/18639	0.272727272727273	2.21980944819373	0.144004561923487	0.49671710537444
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/2290	11/18639	0.272727272727273	2.21980944819373	0.144004561923487	0.49671710537444
GO:0050786	RAGE receptor binding	3/2290	11/18639	0.272727272727273	2.21980944819373	0.144004561923487	0.49671710537444
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	3/2290	11/18639	0.272727272727273	2.21980944819373	0.144004561923487	0.49671710537444
GO:0140537	transcription regulator activator activity	3/2290	11/18639	0.272727272727273	2.21980944819373	0.144004561923487	0.49671710537444
GO:0044390	ubiquitin-like protein conjugating enzyme binding	7/2290	36/18639	0.194444444444444	1.58264192139738	0.145640542214629	0.500987548219174
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/2290	17/18639	0.235294117647059	1.91512972001028	0.147223670268529	0.503680980619778
GO:0038191	neuropilin binding	4/2290	17/18639	0.235294117647059	1.91512972001028	0.147223670268529	0.503680980619778
GO:0008200	ion channel inhibitor activity	8/2290	43/18639	0.186046511627907	1.51428861582208	0.150838503953848	0.514304984593228
GO:0008013	beta-catenin binding	17/2290	106/18639	0.160377358490566	1.30535964406361	0.151146024066318	0.514304984593228
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	20/2290	128/18639	0.15625	1.27176582969432	0.153845495735761	0.517449780255593
GO:0005017	platelet-derived growth factor receptor activity	9/2290	50/18639	0.18	1.46507423580786	0.154012922298962	0.517449780255593
GO:0005019	platelet-derived growth factor beta-receptor activity	9/2290	50/18639	0.18	1.46507423580786	0.154012922298962	0.517449780255593
GO:0001968	fibronectin binding	6/2290	30/18639	0.2	1.62786026200873	0.154947233642858	0.517449780255593
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	6/2290	30/18639	0.2	1.62786026200873	0.154947233642858	0.517449780255593
GO:0008187	poly-pyrimidine tract binding	6/2290	30/18639	0.2	1.62786026200873	0.154947233642858	0.517449780255593
GO:0035925	mRNA 3'-UTR AU-rich region binding	6/2290	30/18639	0.2	1.62786026200873	0.154947233642858	0.517449780255593
GO:0043394	proteoglycan binding	7/2290	37/18639	0.189189189189189	1.53986781541367	0.161764428741994	0.53878681424913
GO:0030215	semaphorin receptor binding	5/2290	24/18639	0.208333333333333	1.69568777292576	0.164082859038233	0.543632419813514
GO:0048027	mRNA 5'-UTR binding	5/2290	24/18639	0.208333333333333	1.69568777292576	0.164082859038233	0.543632419813514
GO:0016248	channel inhibitor activity	8/2290	44/18639	0.181818181818182	1.47987296546249	0.165764692601478	0.545070909044272
GO:0043014	alpha-tubulin binding	8/2290	44/18639	0.181818181818182	1.47987296546249	0.165764692601478	0.545070909044272
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/2290	86/18639	0.162790697674419	1.32500253884432	0.165815852393929	0.545070909044272
GO:0005010	insulin-like growth factor receptor activity	9/2290	51/18639	0.176470588235294	1.43634729000771	0.167927838352007	0.549145840221239
GO:0030544	Hsp70 protein binding	9/2290	51/18639	0.176470588235294	1.43634729000771	0.167927838352007	0.549145840221239
GO:0000900	mRNA regulatory element binding translation repressor activity	4/2290	18/18639	0.222222222222222	1.80873362445415	0.171948323663175	0.550550641991101
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/2290	18/18639	0.222222222222222	1.80873362445415	0.171948323663175	0.550550641991101
GO:0017075	syntaxin-1 binding	4/2290	18/18639	0.222222222222222	1.80873362445415	0.171948323663175	0.550550641991101
GO:0070273	phosphatidylinositol-4-phosphate binding	6/2290	31/18639	0.193548387096774	1.57534864065361	0.173441853505621	0.550550641991101
GO:0016410	N-acyltransferase activity	15/2290	94/18639	0.159574468085106	1.29882467713463	0.174509058299007	0.550550641991101
GO:0042562	hormone binding	15/2290	94/18639	0.159574468085106	1.29882467713463	0.174509058299007	0.550550641991101
GO:0099106	ion channel regulator activity	24/2290	160/18639	0.15	1.22089519650655	0.175069393977621	0.550550641991101
GO:0000340	RNA 7-methylguanosine cap binding	3/2290	12/18639	0.25	2.03482532751092	0.17535409645626	0.550550641991101
GO:0005247	voltage-gated chloride channel activity	3/2290	12/18639	0.25	2.03482532751092	0.17535409645626	0.550550641991101
GO:0008603	cAMP-dependent protein kinase regulator activity	3/2290	12/18639	0.25	2.03482532751092	0.17535409645626	0.550550641991101
GO:0016208	AMP binding	3/2290	12/18639	0.25	2.03482532751092	0.17535409645626	0.550550641991101
GO:0016273	arginine N-methyltransferase activity	3/2290	12/18639	0.25	2.03482532751092	0.17535409645626	0.550550641991101
GO:0016274	protein-arginine N-methyltransferase activity	3/2290	12/18639	0.25	2.03482532751092	0.17535409645626	0.550550641991101
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/2290	12/18639	0.25	2.03482532751092	0.17535409645626	0.550550641991101
GO:0045295	gamma-catenin binding	3/2290	12/18639	0.25	2.03482532751092	0.17535409645626	0.550550641991101
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/2290	12/18639	0.25	2.03482532751092	0.17535409645626	0.550550641991101
GO:0003774	cytoskeletal motor activity	23/2290	153/18639	0.150326797385621	1.22355509889545	0.178422925388965	0.555350176161565
GO:0005501	retinoid binding	7/2290	38/18639	0.184210526315789	1.49934497816594	0.178647197256103	0.555350176161565
GO:0019840	isoprenoid binding	7/2290	38/18639	0.184210526315789	1.49934497816594	0.178647197256103	0.555350176161565
GO:0043531	ADP binding	7/2290	38/18639	0.184210526315789	1.49934497816594	0.178647197256103	0.555350176161565
GO:0141110	transporter inhibitor activity	8/2290	45/18639	0.177777777777778	1.44698689956332	0.181336446528336	0.560120941952788
GO:0004879	nuclear receptor activity	10/2290	59/18639	0.169491525423729	1.37954259492266	0.182388714449397	0.560120941952788
GO:0015459	potassium channel regulator activity	10/2290	59/18639	0.169491525423729	1.37954259492266	0.182388714449397	0.560120941952788
GO:0045309	protein phosphorylated amino acid binding	10/2290	59/18639	0.169491525423729	1.37954259492266	0.182388714449397	0.560120941952788
GO:0005080	protein kinase C binding	9/2290	52/18639	0.173076923076923	1.40872522673833	0.182406343288835	0.560120941952788
GO:0140767	enzyme-substrate adaptor activity	21/2290	139/18639	0.151079136690647	1.22967861518645	0.185329464247671	0.566100915962556
GO:0003707	nuclear steroid receptor activity	5/2290	25/18639	0.2	1.62786026200873	0.185702683314167	0.566100915962556
GO:0017025	TBP-class protein binding	5/2290	25/18639	0.2	1.62786026200873	0.185702683314167	0.566100915962556
GO:0031369	translation initiation factor binding	6/2290	32/18639	0.1875	1.52611899563319	0.192786493143313	0.584863120162484
GO:0120015	sterol transfer activity	6/2290	32/18639	0.1875	1.52611899563319	0.192786493143313	0.584863120162484
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/2290	60/18639	0.166666666666667	1.35655021834061	0.196413926964626	0.593009913785286
GO:0098531	ligand-modulated transcription factor activity	10/2290	60/18639	0.166666666666667	1.35655021834061	0.196413926964626	0.593009913785286
GO:0008574	plus-end-directed microtubule motor activity	4/2290	19/18639	0.210526315789474	1.71353711790393	0.197975532504905	0.593455227199227
GO:0030506	ankyrin binding	4/2290	19/18639	0.210526315789474	1.71353711790393	0.197975532504905	0.593455227199227
GO:0043395	heparan sulfate proteoglycan binding	4/2290	19/18639	0.210526315789474	1.71353711790393	0.197975532504905	0.593455227199227
GO:0008157	protein phosphatase 1 binding	5/2290	26/18639	0.192307692307692	1.56525025193147	0.208281062017966	0.612975385192048
GO:0052742	phosphatidylinositol kinase activity	5/2290	26/18639	0.192307692307692	1.56525025193147	0.208281062017966	0.612975385192048
GO:0070006	metalloaminopeptidase activity	5/2290	26/18639	0.192307692307692	1.56525025193147	0.208281062017966	0.612975385192048
GO:0005172	vascular endothelial growth factor receptor binding	3/2290	13/18639	0.230769230769231	1.87830030231777	0.208354669448079	0.612975385192048
GO:0019104	DNA N-glycosylase activity	3/2290	13/18639	0.230769230769231	1.87830030231777	0.208354669448079	0.612975385192048
GO:0070123	transforming growth factor beta receptor activity, type III	3/2290	13/18639	0.230769230769231	1.87830030231777	0.208354669448079	0.612975385192048
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/2290	13/18639	0.230769230769231	1.87830030231777	0.208354669448079	0.612975385192048
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	11/2290	68/18639	0.161764705882353	1.31665168250706	0.208382418476725	0.612975385192048
GO:0042578	phosphoric ester hydrolase activity	50/2290	363/18639	0.137741046831956	1.12111588292612	0.212187301888861	0.622712850997846
GO:0071949	FAD binding	7/2290	40/18639	0.175	1.42437772925764	0.214469019731433	0.627945339167149
GO:0001972	retinoic acid binding	4/2290	20/18639	0.2	1.62786026200873	0.225088314980722	0.655986547594281
GO:0052745	inositol phosphate phosphatase activity	4/2290	20/18639	0.2	1.62786026200873	0.225088314980722	0.655986547594281
GO:0003697	single-stranded DNA binding	18/2290	121/18639	0.148760330578512	1.21080515356022	0.227216892844455	0.659138405740019
GO:0051082	unfolded protein binding	18/2290	121/18639	0.148760330578512	1.21080515356022	0.227216892844455	0.659138405740019
GO:0140313	molecular sequestering activity	9/2290	55/18639	0.163636363636364	1.33188566891624	0.228900104123641	0.662494784118767
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	8/2290	48/18639	0.166666666666667	1.35655021834061	0.231506429536512	0.664456125384357
GO:0032266	phosphatidylinositol-3-phosphate binding	8/2290	48/18639	0.166666666666667	1.35655021834061	0.231506429536512	0.664456125384357
GO:0001671	ATPase activator activity	5/2290	27/18639	0.185185185185185	1.50727802037846	0.231688831647127	0.664456125384357
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/2290	27/18639	0.185185185185185	1.50727802037846	0.231688831647127	0.664456125384357
GO:0035591	signaling adaptor activity	19/2290	129/18639	0.147286821705426	1.19881182085915	0.232683697133218	0.665792669751639
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	18/2290	122/18639	0.147540983606557	1.20088052115398	0.238020426450127	0.679518632427914
GO:0005507	copper ion binding	10/2290	63/18639	0.158730158730159	1.29195258889582	0.241073596780025	0.684734065147455
GO:0005313	L-glutamate transmembrane transporter activity	3/2290	14/18639	0.214285714285714	1.74413599500936	0.242566634674952	0.684734065147455
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/2290	14/18639	0.214285714285714	1.74413599500936	0.242566634674952	0.684734065147455
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/2290	14/18639	0.214285714285714	1.74413599500936	0.242566634674952	0.684734065147455
GO:0071933	Arp2/3 complex binding	3/2290	14/18639	0.214285714285714	1.74413599500936	0.242566634674952	0.684734065147455
GO:0005004	GPI-linked ephrin receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0005008	hepatocyte growth factor receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0005009	insulin receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0005011	macrophage colony-stimulating factor receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0005018	platelet-derived growth factor alpha-receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0005020	stem cell factor receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0008288	boss receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0036332	placental growth factor receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0038062	protein tyrosine kinase collagen receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0060175	brain-derived neurotrophic factor receptor activity	8/2290	49/18639	0.163265306122449	1.32886552000713	0.249226802486713	0.686764337571459
GO:0005496	steroid binding	16/2290	108/18639	0.148148148148148	1.20582241630277	0.249286181310689	0.686764337571459
GO:0005516	calmodulin binding	29/2290	207/18639	0.140096618357488	1.14028858932979	0.252012355816923	0.691137511275548
GO:0004520	DNA endonuclease activity	7/2290	42/18639	0.166666666666667	1.35655021834061	0.252626507776724	0.691137511275548
GO:0019894	kinesin binding	7/2290	42/18639	0.166666666666667	1.35655021834061	0.252626507776724	0.691137511275548
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/2290	21/18639	0.19047619047619	1.55034310667498	0.253069414374923	0.691137511275548
GO:0003924	GTPase activity	45/2290	331/18639	0.13595166163142	1.10655153761923	0.254807488478251	0.694377982671251
GO:0004601	peroxidase activity	9/2290	57/18639	0.157894736842105	1.28515283842795	0.262079353892784	0.712652065984914
GO:0005006	epidermal growth factor receptor activity	8/2290	50/18639	0.16	1.30228820960699	0.267362779665332	0.723743718802377
GO:0005007	fibroblast growth factor receptor activity	8/2290	50/18639	0.16	1.30228820960699	0.267362779665332	0.723743718802377
GO:0008081	phosphoric diester hydrolase activity	13/2290	87/18639	0.149425287356322	1.21621743713296	0.267882901478878	0.723743718802377
GO:0004712	protein serine/threonine/tyrosine kinase activity	7/2290	43/18639	0.162790697674419	1.32500253884432	0.272418619631171	0.728067847938828
GO:0048156	tau protein binding	7/2290	43/18639	0.162790697674419	1.32500253884432	0.272418619631171	0.728067847938828
GO:0045505	dynein intermediate chain binding	6/2290	36/18639	0.166666666666667	1.35655021834061	0.276968327270925	0.728067847938828
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	6/2290	36/18639	0.166666666666667	1.35655021834061	0.276968327270925	0.728067847938828
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	6/2290	36/18639	0.166666666666667	1.35655021834061	0.276968327270925	0.728067847938828
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	6/2290	36/18639	0.166666666666667	1.35655021834061	0.276968327270925	0.728067847938828
GO:0005041	low-density lipoprotein particle receptor activity	3/2290	15/18639	0.2	1.62786026200873	0.277579481342841	0.728067847938828
GO:0008242	omega peptidase activity	3/2290	15/18639	0.2	1.62786026200873	0.277579481342841	0.728067847938828
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/2290	15/18639	0.2	1.62786026200873	0.277579481342841	0.728067847938828
GO:0031005	filamin binding	3/2290	15/18639	0.2	1.62786026200873	0.277579481342841	0.728067847938828
GO:0045504	dynein heavy chain binding	3/2290	15/18639	0.2	1.62786026200873	0.277579481342841	0.728067847938828
GO:0050780	dopamine receptor binding	3/2290	15/18639	0.2	1.62786026200873	0.277579481342841	0.728067847938828
GO:0051371	muscle alpha-actinin binding	3/2290	15/18639	0.2	1.62786026200873	0.277579481342841	0.728067847938828
GO:0120283	protein serine/threonine kinase binding	3/2290	15/18639	0.2	1.62786026200873	0.277579481342841	0.728067847938828
GO:0043236	laminin binding	5/2290	29/18639	0.172413793103448	1.40332781207649	0.280463783980628	0.731273356444097
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2290	29/18639	0.172413793103448	1.40332781207649	0.280463783980628	0.731273356444097
GO:0015377	chloride:monoatomic cation symporter activity	4/2290	22/18639	0.181818181818182	1.47987296546249	0.281705780679418	0.731273356444097
GO:0016881	acid-amino acid ligase activity	4/2290	22/18639	0.181818181818182	1.47987296546249	0.281705780679418	0.731273356444097
GO:0061133	endopeptidase activator activity	4/2290	22/18639	0.181818181818182	1.47987296546249	0.281705780679418	0.731273356444097
GO:0061134	peptidase regulator activity	31/2290	226/18639	0.13716814159292	1.11645283456351	0.28284776568498	0.732727030858827
GO:0005021	vascular endothelial growth factor receptor activity	8/2290	51/18639	0.156862745098039	1.27675314667352	0.285862303630602	0.734684155470418
GO:0005030	neurotrophin receptor activity	8/2290	51/18639	0.156862745098039	1.27675314667352	0.285862303630602	0.734684155470418
GO:0005048	signal sequence binding	8/2290	51/18639	0.156862745098039	1.27675314667352	0.285862303630602	0.734684155470418
GO:0016791	phosphatase activity	37/2290	273/18639	0.135531135531136	1.10312874898028	0.285937439380862	0.734684155470418
GO:0051087	protein-folding chaperone binding	19/2290	134/18639	0.141791044776119	1.15408003649873	0.287406478012688	0.736954696166954
GO:0001786	phosphatidylserine binding	9/2290	59/18639	0.152542372881356	1.24158833543039	0.296631787019743	0.757524178210661
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	9/2290	59/18639	0.152542372881356	1.24158833543039	0.296631787019743	0.757524178210661
GO:0015399	primary active transmembrane transporter activity	23/2290	166/18639	0.13855421686747	1.12773451886147	0.300917150004826	0.766912331692461
GO:0022839	monoatomic ion-gated channel activity	5/2290	30/18639	0.166666666666667	1.35655021834061	0.305567094048182	0.772906622811499
GO:0019210	kinase inhibitor activity	13/2290	90/18639	0.144444444444444	1.1756768558952	0.310126513779465	0.772906622811499
GO:0003887	DNA-directed DNA polymerase activity	4/2290	23/18639	0.173913043478261	1.41553066261629	0.310792187157401	0.772906622811499
GO:0005158	insulin receptor binding	4/2290	23/18639	0.173913043478261	1.41553066261629	0.310792187157401	0.772906622811499
GO:0016849	phosphorus-oxygen lyase activity	4/2290	23/18639	0.173913043478261	1.41553066261629	0.310792187157401	0.772906622811499
GO:0031681	G-protein beta-subunit binding	4/2290	23/18639	0.173913043478261	1.41553066261629	0.310792187157401	0.772906622811499
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/2290	23/18639	0.173913043478261	1.41553066261629	0.310792187157401	0.772906622811499
GO:0005521	lamin binding	3/2290	16/18639	0.1875	1.52611899563319	0.313017927765156	0.772906622811499
GO:0015378	sodium:chloride symporter activity	3/2290	16/18639	0.1875	1.52611899563319	0.313017927765156	0.772906622811499
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/2290	16/18639	0.1875	1.52611899563319	0.313017927765156	0.772906622811499
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/2290	16/18639	0.1875	1.52611899563319	0.313017927765156	0.772906622811499
GO:0022858	alanine transmembrane transporter activity	3/2290	16/18639	0.1875	1.52611899563319	0.313017927765156	0.772906622811499
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/2290	16/18639	0.1875	1.52611899563319	0.313017927765156	0.772906622811499
GO:0097027	ubiquitin-protein transferase activator activity	3/2290	16/18639	0.1875	1.52611899563319	0.313017927765156	0.772906622811499
GO:0004715	non-membrane spanning protein tyrosine kinase activity	7/2290	45/18639	0.155555555555556	1.2661135371179	0.313091642282656	0.772906622811499
GO:0140303	intramembrane lipid transporter activity	7/2290	45/18639	0.155555555555556	1.2661135371179	0.313091642282656	0.772906622811499
GO:0005003	ephrin receptor activity	8/2290	53/18639	0.150943396226415	1.2285737826481	0.323740039966279	0.794519903153109
GO:0005005	transmembrane-ephrin receptor activity	8/2290	53/18639	0.150943396226415	1.2285737826481	0.323740039966279	0.794519903153109
GO:0038064	collagen receptor activity	8/2290	53/18639	0.150943396226415	1.2285737826481	0.323740039966279	0.794519903153109
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	7/2290	46/18639	0.152173913043478	1.23858932978925	0.333836427594766	0.810616148045371
GO:0004860	protein kinase inhibitor activity	12/2290	84/18639	0.142857142857143	1.16275733000624	0.334397269096035	0.810616148045371
GO:0005506	iron ion binding	21/2290	154/18639	0.136363636363636	1.10990472409686	0.339081731423774	0.810616148045371
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/2290	24/18639	0.166666666666667	1.35655021834061	0.340134052781235	0.810616148045371
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/2290	24/18639	0.166666666666667	1.35655021834061	0.340134052781235	0.810616148045371
GO:0005540	hyaluronic acid binding	4/2290	24/18639	0.166666666666667	1.35655021834061	0.340134052781235	0.810616148045371
GO:0140612	DNA damage sensor activity	4/2290	24/18639	0.166666666666667	1.35655021834061	0.340134052781235	0.810616148045371
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	6/2290	39/18639	0.153846153846154	1.25220020154518	0.344726764173153	0.810616148045371
GO:0004659	prenyltransferase activity	3/2290	17/18639	0.176470588235294	1.43634729000771	0.348545268657292	0.810616148045371
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/2290	17/18639	0.176470588235294	1.43634729000771	0.348545268657292	0.810616148045371
GO:0005092	GDP-dissociation inhibitor activity	3/2290	17/18639	0.176470588235294	1.43634729000771	0.348545268657292	0.810616148045371
GO:0008484	sulfuric ester hydrolase activity	3/2290	17/18639	0.176470588235294	1.43634729000771	0.348545268657292	0.810616148045371
GO:0019198	transmembrane receptor protein phosphatase activity	3/2290	17/18639	0.176470588235294	1.43634729000771	0.348545268657292	0.810616148045371
GO:0032183	SUMO binding	3/2290	17/18639	0.176470588235294	1.43634729000771	0.348545268657292	0.810616148045371
GO:0070402	NADPH binding	3/2290	17/18639	0.176470588235294	1.43634729000771	0.348545268657292	0.810616148045371
GO:0070403	NAD+ binding	3/2290	17/18639	0.176470588235294	1.43634729000771	0.348545268657292	0.810616148045371
GO:0004382	GDP phosphatase activity	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0005131	growth hormone receptor binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0005528	FK506 binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0015279	store-operated calcium channel activity	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0030957	Tat protein binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0031419	cobalamin binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0043121	neurotrophin binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0043208	glycosphingolipid binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0043422	protein kinase B binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0070513	death domain binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0099122	RNA polymerase II C-terminal domain binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0140940	histone H2A methyltransferase activity	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0141109	transporter activator activity	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:1990259	histone H2AQ104 methyltransferase activity	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:1990763	arrestin family protein binding	2/2290	10/18639	0.2	1.62786026200873	0.352833716543974	0.810616148045371
GO:0097110	scaffold protein binding	10/2290	70/18639	0.142857142857143	1.16275733000624	0.35621316332104	0.816889567616011
GO:0016209	antioxidant activity	12/2290	86/18639	0.13953488372093	1.13571646186656	0.365258218681177	0.833804454524599
GO:0050660	flavin adenine dinucleotide binding	12/2290	86/18639	0.13953488372093	1.13571646186656	0.365258218681177	0.833804454524599
GO:0004177	aminopeptidase activity	6/2290	40/18639	0.15	1.22089519650655	0.367713424956987	0.833804454524599
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	6/2290	40/18639	0.15	1.22089519650655	0.367713424956987	0.833804454524599
GO:0004709	MAP kinase kinase kinase activity	4/2290	25/18639	0.16	1.30228820960699	0.369549551727344	0.833804454524599
GO:0008483	transaminase activity	4/2290	25/18639	0.16	1.30228820960699	0.369549551727344	0.833804454524599
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/2290	25/18639	0.16	1.30228820960699	0.369549551727344	0.833804454524599
GO:0047617	fatty acyl-CoA hydrolase activity	4/2290	25/18639	0.16	1.30228820960699	0.369549551727344	0.833804454524599
GO:0120020	cholesterol transfer activity	4/2290	25/18639	0.16	1.30228820960699	0.369549551727344	0.833804454524599
GO:0140299	molecular sensor activity	10/2290	71/18639	0.140845070422535	1.14638046620333	0.373400399028606	0.840985871873014
GO:0022853	active monoatomic ion transmembrane transporter activity	16/2290	118/18639	0.135593220338983	1.10363407593812	0.37676711573561	0.841948753674699
GO:0140311	protein sequestering activity	5/2290	33/18639	0.151515151515152	1.23322747121874	0.382221263920437	0.841948753674699
GO:0140416	transcription regulator inhibitor activity	5/2290	33/18639	0.151515151515152	1.23322747121874	0.382221263920437	0.841948753674699
GO:0004706	JUN kinase kinase kinase activity	3/2290	18/18639	0.166666666666667	1.35655021834061	0.383864657656115	0.841948753674699
GO:0008308	voltage-gated monoatomic anion channel activity	3/2290	18/18639	0.166666666666667	1.35655021834061	0.383864657656115	0.841948753674699
GO:0015373	monoatomic anion:sodium symporter activity	3/2290	18/18639	0.166666666666667	1.35655021834061	0.383864657656115	0.841948753674699
GO:0030228	lipoprotein particle receptor activity	3/2290	18/18639	0.166666666666667	1.35655021834061	0.383864657656115	0.841948753674699
GO:0034185	apolipoprotein binding	3/2290	18/18639	0.166666666666667	1.35655021834061	0.383864657656115	0.841948753674699
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/2290	18/18639	0.166666666666667	1.35655021834061	0.383864657656115	0.841948753674699
GO:0070064	proline-rich region binding	3/2290	18/18639	0.166666666666667	1.35655021834061	0.383864657656115	0.841948753674699
GO:0098641	cadherin binding involved in cell-cell adhesion	3/2290	18/18639	0.166666666666667	1.35655021834061	0.383864657656115	0.841948753674699
GO:0004536	DNA nuclease activity	9/2290	64/18639	0.140625	1.14458924672489	0.386785126011175	0.841948753674699
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	6/2290	41/18639	0.146341463414634	1.19111726488444	0.39075782032007	0.841948753674699
GO:0016763	pentosyltransferase activity	7/2290	49/18639	0.142857142857143	1.16275733000624	0.396904338952123	0.841948753674699
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/2290	26/18639	0.153846153846154	1.25220020154518	0.398871095310867	0.841948753674699
GO:0005112	Notch binding	4/2290	26/18639	0.153846153846154	1.25220020154518	0.398871095310867	0.841948753674699
GO:0005227	calcium-activated cation channel activity	4/2290	26/18639	0.153846153846154	1.25220020154518	0.398871095310867	0.841948753674699
GO:0008198	ferrous iron binding	4/2290	26/18639	0.153846153846154	1.25220020154518	0.398871095310867	0.841948753674699
GO:0016289	acyl-CoA hydrolase activity	4/2290	26/18639	0.153846153846154	1.25220020154518	0.398871095310867	0.841948753674699
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0004016	adenylate cyclase activity	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0008199	ferric iron binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0008432	JUN kinase binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0019215	intermediate filament binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0032050	clathrin heavy chain binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0034511	U3 snoRNA binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0034713	type I transforming growth factor beta receptor binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0045294	alpha-catenin binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0048185	activin binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0050998	nitric-oxide synthase binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0070697	activin receptor binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0070990	snRNP binding	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:1990948	ubiquitin ligase inhibitor activity	2/2290	11/18639	0.181818181818182	1.47987296546249	0.399240195348527	0.841948753674699
GO:0008376	acetylgalactosaminyltransferase activity	5/2290	34/18639	0.147058823529412	1.19695607500642	0.407829479267889	0.855762190663787
GO:0015035	protein-disulfide reductase activity	5/2290	34/18639	0.147058823529412	1.19695607500642	0.407829479267889	0.855762190663787
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/2290	34/18639	0.147058823529412	1.19695607500642	0.407829479267889	0.855762190663787
GO:0016859	cis-trans isomerase activity	6/2290	42/18639	0.142857142857143	1.16275733000624	0.413779705743961	0.865627349088761
GO:0005229	intracellularly calcium-gated chloride channel activity	3/2290	19/18639	0.157894736842105	1.28515283842795	0.418718868621967	0.865627349088761
GO:0005520	insulin-like growth factor binding	3/2290	19/18639	0.157894736842105	1.28515283842795	0.418718868621967	0.865627349088761
GO:0008301	DNA binding, bending	3/2290	19/18639	0.157894736842105	1.28515283842795	0.418718868621967	0.865627349088761
GO:0016918	retinal binding	3/2290	19/18639	0.157894736842105	1.28515283842795	0.418718868621967	0.865627349088761
GO:0031420	alkali metal ion binding	3/2290	19/18639	0.157894736842105	1.28515283842795	0.418718868621967	0.865627349088761
GO:0046624	sphingolipid transporter activity	3/2290	19/18639	0.157894736842105	1.28515283842795	0.418718868621967	0.865627349088761
GO:0097001	ceramide binding	3/2290	19/18639	0.157894736842105	1.28515283842795	0.418718868621967	0.865627349088761
GO:0141147	intracellularly calcium-gated channel activity	3/2290	19/18639	0.157894736842105	1.28515283842795	0.418718868621967	0.865627349088761
GO:0042277	peptide binding	32/2290	249/18639	0.1285140562249	1.04601462619035	0.420976155670906	0.868867180310935
GO:0048029	monosaccharide binding	10/2290	74/18639	0.135135135135135	1.09990558243833	0.42529284719101	0.874832434499011
GO:0005044	scavenger receptor activity	4/2290	27/18639	0.148148148148148	1.20582241630277	0.427946271600213	0.874832434499011
GO:0005104	fibroblast growth factor receptor binding	4/2290	27/18639	0.148148148148148	1.20582241630277	0.427946271600213	0.874832434499011
GO:0005385	zinc ion transmembrane transporter activity	4/2290	27/18639	0.148148148148148	1.20582241630277	0.427946271600213	0.874832434499011
GO:0008320	protein transmembrane transporter activity	4/2290	27/18639	0.148148148148148	1.20582241630277	0.427946271600213	0.874832434499011
GO:0005154	epidermal growth factor receptor binding	5/2290	35/18639	0.142857142857143	1.16275733000624	0.433287665296725	0.874832434499011
GO:0005245	voltage-gated calcium channel activity	6/2290	43/18639	0.13953488372093	1.13571646186656	0.436703125113603	0.874832434499011
GO:0016500	protein-hormone receptor activity	9/2290	67/18639	0.134328358208955	1.09333898194616	0.441772266893594	0.874832434499011
GO:0070851	growth factor receptor binding	18/2290	139/18639	0.129496402877698	1.05401024158839	0.443802700505739	0.874832434499011
GO:0005262	calcium channel activity	17/2290	131/18639	0.129770992366412	1.05624520817361	0.443921842047658	0.874832434499011
GO:0031072	heat shock protein binding	17/2290	131/18639	0.129770992366412	1.05624520817361	0.443921842047658	0.874832434499011
GO:0004300	enoyl-CoA hydratase activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0005025	transforming growth factor beta receptor activity, type I	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0005026	transforming growth factor beta receptor activity, type II	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0005049	nuclear export signal receptor activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0005078	MAP-kinase scaffold activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0005095	GTPase inhibitor activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0005527	macrolide binding	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0008179	adenylate cyclase binding	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0008504	monoamine transmembrane transporter activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0010853	cyclase activator activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0015269	calcium-activated potassium channel activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0016361	activin receptor activity, type I	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0016362	activin receptor activity, type II	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0016423	tRNA (guanine) methyltransferase activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0017002	activin receptor activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0036009	protein-glutamine N-methyltransferase activity	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0043047	single-stranded telomeric DNA binding	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2290	12/18639	0.166666666666667	1.35655021834061	0.44401741512698	0.874832434499011
GO:0000339	RNA cap binding	3/2290	20/18639	0.15	1.22089519650655	0.452888966323363	0.878835304277084
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/2290	20/18639	0.15	1.22089519650655	0.452888966323363	0.878835304277084
GO:0010851	cyclase regulator activity	3/2290	20/18639	0.15	1.22089519650655	0.452888966323363	0.878835304277084
GO:0016004	phospholipase activator activity	3/2290	20/18639	0.15	1.22089519650655	0.452888966323363	0.878835304277084
GO:0016408	C-acyltransferase activity	3/2290	20/18639	0.15	1.22089519650655	0.452888966323363	0.878835304277084
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/2290	20/18639	0.15	1.22089519650655	0.452888966323363	0.878835304277084
GO:0140664	ATP-dependent DNA damage sensor activity	3/2290	20/18639	0.15	1.22089519650655	0.452888966323363	0.878835304277084
GO:0046875	ephrin receptor binding	4/2290	28/18639	0.142857142857143	1.16275733000624	0.456638324797739	0.878835304277084
GO:0050698	proteoglycan sulfotransferase activity	4/2290	28/18639	0.142857142857143	1.16275733000624	0.456638324797739	0.878835304277084
GO:0051019	mitogen-activated protein kinase binding	4/2290	28/18639	0.142857142857143	1.16275733000624	0.456638324797739	0.878835304277084
GO:0051393	alpha-actinin binding	4/2290	28/18639	0.142857142857143	1.16275733000624	0.456638324797739	0.878835304277084
GO:0051537	2 iron, 2 sulfur cluster binding	4/2290	28/18639	0.142857142857143	1.16275733000624	0.456638324797739	0.878835304277084
GO:0051959	dynein light intermediate chain binding	4/2290	28/18639	0.142857142857143	1.16275733000624	0.456638324797739	0.878835304277084
GO:0097718	disordered domain specific binding	4/2290	28/18639	0.142857142857143	1.16275733000624	0.456638324797739	0.878835304277084
GO:0055106	ubiquitin-protein transferase regulator activity	5/2290	36/18639	0.138888888888889	1.13045851528384	0.458500461752498	0.878835304277084
GO:0043178	alcohol binding	12/2290	92/18639	0.130434782608696	1.06164799696222	0.45920825808453	0.878835304277084
GO:0004527	exonuclease activity	11/2290	84/18639	0.130952380952381	1.06586088583905	0.459551093786055	0.878835304277084
GO:0098631	cell adhesion mediator activity	10/2290	76/18639	0.131578947368421	1.07096069868996	0.459827155303304	0.878835304277084
GO:0030159	signaling receptor complex adaptor activity	7/2290	52/18639	0.134615384615385	1.09567517635203	0.459910660384443	0.878835304277084
GO:0032934	sterol binding	9/2290	68/18639	0.132352941176471	1.07726046750578	0.460009901126766	0.878835304277084
GO:0000287	magnesium ion binding	29/2290	230/18639	0.126086956521739	1.02625973039681	0.470621003511278	0.897745217304089
GO:0033218	amide binding	31/2290	247/18639	0.125506072874494	1.0215317433658	0.47851982382274	0.909930013286097
GO:0015026	coreceptor activity	8/2290	61/18639	0.131147540983607	1.06744935213687	0.479355780989535	0.909930013286097
GO:0004864	protein phosphatase inhibitor activity	7/2290	53/18639	0.132075471698113	1.07500205981709	0.480632276535033	0.909930013286097
GO:0005544	calcium-dependent phospholipid binding	7/2290	53/18639	0.132075471698113	1.07500205981709	0.480632276535033	0.909930013286097
GO:0008146	sulfotransferase activity	7/2290	53/18639	0.132075471698113	1.07500205981709	0.480632276535033	0.909930013286097
GO:0005123	death receptor binding	3/2290	21/18639	0.142857142857143	1.16275733000624	0.486192224981436	0.909930013286097
GO:0005248	voltage-gated sodium channel activity	3/2290	21/18639	0.142857142857143	1.16275733000624	0.486192224981436	0.909930013286097
GO:0009975	cyclase activity	3/2290	21/18639	0.142857142857143	1.16275733000624	0.486192224981436	0.909930013286097
GO:0035613	RNA stem-loop binding	3/2290	21/18639	0.142857142857143	1.16275733000624	0.486192224981436	0.909930013286097
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/2290	13/18639	0.153846153846154	1.25220020154518	0.486865187068598	0.909930013286097
GO:0008035	high-density lipoprotein particle binding	2/2290	13/18639	0.153846153846154	1.25220020154518	0.486865187068598	0.909930013286097
GO:0008253	5'-nucleotidase activity	2/2290	13/18639	0.153846153846154	1.25220020154518	0.486865187068598	0.909930013286097
GO:0031994	insulin-like growth factor I binding	2/2290	13/18639	0.153846153846154	1.25220020154518	0.486865187068598	0.909930013286097
GO:0004222	metalloendopeptidase activity	14/2290	110/18639	0.127272727272727	1.03591107582374	0.487126949130126	0.909930013286097
GO:0004721	phosphoprotein phosphatase activity	22/2290	175/18639	0.125714285714286	1.02322645040549	0.488603180569059	0.911335413831771
GO:0003925	G protein activity	7/2290	54/18639	0.12962962962963	1.05509461426492	0.50112894289963	0.927785743050629
GO:0015485	cholesterol binding	7/2290	54/18639	0.12962962962963	1.05509461426492	0.50112894289963	0.927785743050629
GO:0050661	NADP binding	7/2290	54/18639	0.12962962962963	1.05509461426492	0.50112894289963	0.927785743050629
GO:0030291	protein serine/threonine kinase inhibitor activity	6/2290	46/18639	0.130434782608696	1.06164799696222	0.504195256713234	0.927785743050629
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	5/2290	38/18639	0.131578947368421	1.07096069868996	0.507850416529054	0.927785743050629
GO:0016769	transferase activity, transferring nitrogenous groups	4/2290	30/18639	0.133333333333333	1.08524017467249	0.512404583217752	0.927785743050629
GO:0031210	phosphatidylcholine binding	4/2290	30/18639	0.133333333333333	1.08524017467249	0.512404583217752	0.927785743050629
GO:0048019	receptor antagonist activity	4/2290	30/18639	0.133333333333333	1.08524017467249	0.512404583217752	0.927785743050629
GO:0051721	protein phosphatase 2A binding	4/2290	30/18639	0.133333333333333	1.08524017467249	0.512404583217752	0.927785743050629
GO:1901682	sulfur compound transmembrane transporter activity	8/2290	63/18639	0.126984126984127	1.03356207111666	0.517382809958491	0.927785743050629
GO:0004407	histone deacetylase activity	3/2290	22/18639	0.136363636363636	1.10990472409686	0.518479558292281	0.927785743050629
GO:0008093	cytoskeletal anchor activity	3/2290	22/18639	0.136363636363636	1.10990472409686	0.518479558292281	0.927785743050629
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2290	22/18639	0.136363636363636	1.10990472409686	0.518479558292281	0.927785743050629
GO:0033558	protein lysine deacetylase activity	3/2290	22/18639	0.136363636363636	1.10990472409686	0.518479558292281	0.927785743050629
GO:0034062	5'-3' RNA polymerase activity	3/2290	22/18639	0.136363636363636	1.10990472409686	0.518479558292281	0.927785743050629
GO:0070034	telomerase RNA binding	3/2290	22/18639	0.136363636363636	1.10990472409686	0.518479558292281	0.927785743050629
GO:0097747	RNA polymerase activity	3/2290	22/18639	0.136363636363636	1.10990472409686	0.518479558292281	0.927785743050629
GO:0098632	cell-cell adhesion mediator activity	7/2290	55/18639	0.127272727272727	1.03591107582374	0.521355132674186	0.927785743050629
GO:0001784	phosphotyrosine residue binding	6/2290	47/18639	0.127659574468085	1.0390597417077	0.526063298927598	0.927785743050629
GO:0005504	fatty acid binding	6/2290	47/18639	0.127659574468085	1.0390597417077	0.526063298927598	0.927785743050629
GO:0140359	ABC-type transporter activity	6/2290	47/18639	0.127659574468085	1.0390597417077	0.526063298927598	0.927785743050629
GO:0004540	RNA nuclease activity	15/2290	121/18639	0.12396694214876	1.00900429463351	0.526750310144146	0.927785743050629
GO:0015108	chloride transmembrane transporter activity	15/2290	121/18639	0.12396694214876	1.00900429463351	0.526750310144146	0.927785743050629
GO:0004065	arylsulfatase activity	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0004705	JUN kinase activity	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0005344	oxygen carrier activity	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0005545	1-phosphatidylinositol binding	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0008494	translation activator activity	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0008559	ABC-type xenobiotic transporter activity	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0019992	diacylglycerol binding	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0034236	protein kinase A catalytic subunit binding	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0042043	neurexin family protein binding	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0044548	S100 protein binding	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0061665	SUMO ligase activity	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0070742	C2H2 zinc finger domain binding	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0098599	palmitoyl hydrolase activity	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0098821	BMP receptor activity	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0098847	sequence-specific single stranded DNA binding	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:1990825	sequence-specific mRNA binding	2/2290	14/18639	0.142857142857143	1.16275733000624	0.527581612467539	0.927785743050629
GO:0048306	calcium-dependent protein binding	10/2290	80/18639	0.125	1.01741266375546	0.527636689455322	0.927785743050629
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2290	31/18639	0.129032258064516	1.05023242710241	0.539282922338527	0.944307648434222
GO:0008327	methyl-CpG binding	4/2290	31/18639	0.129032258064516	1.05023242710241	0.539282922338527	0.944307648434222
GO:0016411	acylglycerol O-acyltransferase activity	4/2290	31/18639	0.129032258064516	1.05023242710241	0.539282922338527	0.944307648434222
GO:0019212	phosphatase inhibitor activity	7/2290	56/18639	0.125	1.01741266375546	0.541269005891136	0.945387031480311
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	28/2290	229/18639	0.122270742358079	0.995198413455121	0.541401151467279	0.945387031480311
GO:0015085	calcium ion transmembrane transporter activity	18/2290	147/18639	0.122448979591837	0.996649140005347	0.543933854001349	0.947586054421227
GO:0030971	receptor tyrosine kinase binding	10/2290	81/18639	0.123456790123457	1.00485201358564	0.54416578025937	0.947586054421227
GO:0004602	glutathione peroxidase activity	3/2290	23/18639	0.130434782608696	1.06164799696222	0.549632663962512	0.955783872829839
GO:0042626	ATPase-coupled transmembrane transporter activity	12/2290	98/18639	0.122448979591837	0.996649140005347	0.551155228200611	0.957109561799407
GO:0038024	cargo receptor activity	8/2290	65/18639	0.123076923076923	1.00176016123614	0.554414090576288	0.957677712118544
GO:0004532	RNA exonuclease activity	5/2290	40/18639	0.125	1.01741266375546	0.555285726645383	0.957677712118544
GO:0015036	disulfide oxidoreductase activity	5/2290	40/18639	0.125	1.01741266375546	0.555285726645383	0.957677712118544
GO:0061791	GTPase motor activity	5/2290	40/18639	0.125	1.01741266375546	0.555285726645383	0.957677712118544
GO:1990606	membrane scission GTPase motor activity	5/2290	40/18639	0.125	1.01741266375546	0.555285726645383	0.957677712118544
GO:0022884	macromolecule transmembrane transporter activity	4/2290	32/18639	0.125	1.01741266375546	0.565385281893956	0.959150390043296
GO:0051059	NF-kappaB binding	4/2290	32/18639	0.125	1.01741266375546	0.565385281893956	0.959150390043296
GO:0071813	lipoprotein particle binding	4/2290	32/18639	0.125	1.01741266375546	0.565385281893956	0.959150390043296
GO:0071814	protein-lipid complex binding	4/2290	32/18639	0.125	1.01741266375546	0.565385281893956	0.959150390043296
GO:0140142	nucleocytoplasmic carrier activity	4/2290	32/18639	0.125	1.01741266375546	0.565385281893956	0.959150390043296
GO:0004129	cytochrome-c oxidase activity	2/2290	15/18639	0.133333333333333	1.08524017467249	0.566043478794415	0.959150390043296
GO:0005523	tropomyosin binding	2/2290	15/18639	0.133333333333333	1.08524017467249	0.566043478794415	0.959150390043296
GO:0008252	nucleotidase activity	2/2290	15/18639	0.133333333333333	1.08524017467249	0.566043478794415	0.959150390043296
GO:0015116	sulfate transmembrane transporter activity	2/2290	15/18639	0.133333333333333	1.08524017467249	0.566043478794415	0.959150390043296
GO:0017081	chloride channel regulator activity	2/2290	15/18639	0.133333333333333	1.08524017467249	0.566043478794415	0.959150390043296
GO:0034483	heparan sulfate sulfotransferase activity	2/2290	15/18639	0.133333333333333	1.08524017467249	0.566043478794415	0.959150390043296
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/2290	15/18639	0.133333333333333	1.08524017467249	0.566043478794415	0.959150390043296
GO:0140776	protein-containing complex destabilizing activity	2/2290	15/18639	0.133333333333333	1.08524017467249	0.566043478794415	0.959150390043296
GO:0060590	ATPase regulator activity	6/2290	49/18639	0.122448979591837	0.996649140005347	0.568545717907751	0.962095509201423
GO:0008235	metalloexopeptidase activity	8/2290	66/18639	0.121212121212121	0.98658197697499	0.572476226733285	0.967446401955981
GO:0005254	chloride channel activity	10/2290	83/18639	0.120481927710843	0.980638712053454	0.576546917497429	0.967728575024412
GO:0030165	PDZ domain binding	10/2290	83/18639	0.120481927710843	0.980638712053454	0.576546917497429	0.967728575024412
GO:0140318	protein transporter activity	5/2290	41/18639	0.121951219512195	0.992597720737033	0.57813682474612	0.967728575024412
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/2290	24/18639	0.125	1.01741266375546	0.579561036988409	0.967728575024412
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/2290	24/18639	0.125	1.01741266375546	0.579561036988409	0.967728575024412
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/2290	24/18639	0.125	1.01741266375546	0.579561036988409	0.967728575024412
GO:0050699	WW domain binding	3/2290	24/18639	0.125	1.01741266375546	0.579561036988409	0.967728575024412
GO:0060229	lipase activator activity	3/2290	24/18639	0.125	1.01741266375546	0.579561036988409	0.967728575024412
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/2290	24/18639	0.125	1.01741266375546	0.579561036988409	0.967728575024412
GO:1990782	protein tyrosine kinase binding	14/2290	117/18639	0.11965811965812	0.973933490090695	0.58449187143011	0.974669226662925
GO:0019956	chemokine binding	4/2290	33/18639	0.121212121212121	0.98658197697499	0.590649284373063	0.983634191832918
GO:0017022	myosin binding	9/2290	76/18639	0.118421052631579	0.963864628820961	0.59942270179361	0.984619730493696
GO:0008307	structural constituent of muscle	5/2290	42/18639	0.119047619047619	0.968964441671865	0.600347246232899	0.984619730493696
GO:0042056	chemoattractant activity	5/2290	42/18639	0.119047619047619	0.968964441671865	0.600347246232899	0.984619730493696
GO:0051879	Hsp90 protein binding	5/2290	42/18639	0.119047619047619	0.968964441671865	0.600347246232899	0.984619730493696
GO:0004707	MAP kinase activity	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0015562	efflux transmembrane transporter activity	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0017070	U6 snRNA binding	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0019841	retinol binding	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0030275	LRR domain binding	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0043023	ribosomal large subunit binding	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0055102	lipase inhibitor activity	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0140327	flippase activity	2/2290	16/18639	0.125	1.01741266375546	0.602189986084309	0.984619730493696
GO:0030145	manganese ion binding	8/2290	68/18639	0.117647058823529	0.957564860005138	0.607557317083305	0.991868522276025
GO:0005537	D-mannose binding	3/2290	25/18639	0.12	0.97671615720524	0.608198966796736	0.991868522276025
GO:0008238	exopeptidase activity	12/2290	102/18639	0.117647058823529	0.957564860005138	0.609145272476805	0.992126646893012
GO:0140789	histone phosphatase activity	16/2290	136/18639	0.117647058823529	0.957564860005138	0.612957908279243	0.997046520056288
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/2290	60/18639	0.116666666666667	0.949585152838428	0.617095309244446	0.999999999920195
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5/2290	43/18639	0.116279069767442	0.946430384888799	0.621879367432806	0.999999999920195
GO:0004435	phosphatidylinositol phospholipase C activity	3/2290	26/18639	0.115384615384615	0.939150151158885	0.635502602207936	0.999999999920195
GO:0030247	polysaccharide binding	3/2290	26/18639	0.115384615384615	0.939150151158885	0.635502602207936	0.999999999920195
GO:0097602	cullin family protein binding	3/2290	26/18639	0.115384615384615	0.939150151158885	0.635502602207936	0.999999999920195
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0008429	phosphatidylethanolamine binding	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0008569	minus-end-directed microtubule motor activity	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0016018	cyclosporin A binding	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0017110	nucleoside diphosphate phosphatase activity	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0030169	low-density lipoprotein particle binding	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0031489	myosin V binding	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0048038	quinone binding	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0051787	misfolded protein binding	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0070492	oligosaccharide binding	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:1990226	histone methyltransferase binding	2/2290	17/18639	0.117647058823529	0.957564860005138	0.636009281741245	0.999999999920195
GO:0034061	DNA polymerase activity	4/2290	35/18639	0.114285714285714	0.930205864004991	0.638475270398745	0.999999999920195
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/2290	70/18639	0.114285714285714	0.930205864004991	0.641097789060044	0.999999999920195
GO:0016790	thiolester hydrolase activity	5/2290	44/18639	0.113636363636364	0.924920603414053	0.642702770925069	0.999999999920195
GO:0019205	nucleobase-containing compound kinase activity	5/2290	44/18639	0.113636363636364	0.924920603414053	0.642702770925069	0.999999999920195
GO:0033293	monocarboxylic acid binding	9/2290	79/18639	0.113924050632911	0.927262174561937	0.646993337485219	0.999999999920195
GO:0015179	L-amino acid transmembrane transporter activity	7/2290	62/18639	0.112903225806452	0.918953373714608	0.65231985753612	0.999999999920195
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/2290	36/18639	0.111111111111111	0.904366812227074	0.660972121479526	0.999999999920195
GO:0046915	transition metal ion transmembrane transporter activity	5/2290	45/18639	0.111111111111111	0.904366812227074	0.662793799806741	0.999999999920195
GO:0008509	monoatomic anion transmembrane transporter activity	17/2290	149/18639	0.114093959731544	0.928645115911023	0.665395314354851	0.999999999920195
GO:0017069	snRNA binding	6/2290	54/18639	0.111111111111111	0.904366812227074	0.665710263810364	0.999999999920195
GO:0051287	NAD binding	6/2290	54/18639	0.111111111111111	0.904366812227074	0.665710263810364	0.999999999920195
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	10/2290	89/18639	0.112359550561798	0.914528237083558	0.666919519763826	0.999999999920195
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	10/2290	89/18639	0.112359550561798	0.914528237083558	0.666919519763826	0.999999999920195
GO:0003746	translation elongation factor activity	2/2290	18/18639	0.111111111111111	0.904366812227074	0.667527359751886	0.999999999920195
GO:0015280	ligand-gated sodium channel activity	2/2290	18/18639	0.111111111111111	0.904366812227074	0.667527359751886	0.999999999920195
GO:0017128	phospholipid scramblase activity	2/2290	18/18639	0.111111111111111	0.904366812227074	0.667527359751886	0.999999999920195
GO:0070628	proteasome binding	2/2290	18/18639	0.111111111111111	0.904366812227074	0.667527359751886	0.999999999920195
GO:0004518	nuclease activity	24/2290	209/18639	0.114832535885167	0.93465660976578	0.670229066082559	0.999999999920195
GO:0004725	protein tyrosine phosphatase activity	11/2290	98/18639	0.112244897959184	0.913595045004902	0.671615122126906	0.999999999920195
GO:0008237	metallopeptidase activity	21/2290	184/18639	0.114130434782609	0.92894199734194	0.674841939961507	0.999999999920195
GO:0019842	vitamin binding	17/2290	150/18639	0.113333333333333	0.922454148471616	0.676293338431402	0.999999999920195
GO:0009055	electron transfer activity	13/2290	116/18639	0.112068965517241	0.912163077849722	0.680676182453186	0.999999999920195
GO:0140793	histone H2AXY142 phosphatase activity	10/2290	90/18639	0.111111111111111	0.904366812227074	0.680840217663382	0.999999999920195
GO:0042805	actinin binding	4/2290	37/18639	0.108108108108108	0.879924465950667	0.682498333913597	0.999999999920195
GO:0008374	O-acyltransferase activity	6/2290	55/18639	0.109090909090909	0.887923779277491	0.683386402316835	0.999999999920195
GO:0016866	intramolecular transferase activity	3/2290	28/18639	0.107142857142857	0.872067997504679	0.686024201782241	0.999999999920195
GO:0046625	sphingolipid binding	3/2290	28/18639	0.107142857142857	0.872067997504679	0.686024201782241	0.999999999920195
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	9/2290	82/18639	0.109756097560976	0.893337948663329	0.691217322297071	0.999999999920195
GO:0072341	modified amino acid binding	10/2290	91/18639	0.10989010989011	0.894428715389414	0.694406437712853	0.999999999920195
GO:0015245	fatty acid transmembrane transporter activity	2/2290	19/18639	0.105263157894737	0.856768558951965	0.696798946943642	0.999999999920195
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/2290	19/18639	0.105263157894737	0.856768558951965	0.696798946943642	0.999999999920195
GO:0050145	nucleoside monophosphate kinase activity	2/2290	19/18639	0.105263157894737	0.856768558951965	0.696798946943642	0.999999999920195
GO:0070003	threonine-type peptidase activity	2/2290	19/18639	0.105263157894737	0.856768558951965	0.696798946943642	0.999999999920195
GO:0046906	tetrapyrrole binding	17/2290	152/18639	0.111842105263158	0.910316593886463	0.697489128174143	0.999999999920195
GO:0030170	pyridoxal phosphate binding	6/2290	56/18639	0.107142857142857	0.872067997504679	0.700440489887919	0.999999999920195
GO:0120013	lipid transfer activity	7/2290	65/18639	0.107692307692308	0.876540141081626	0.70136376949879	0.999999999920195
GO:0160215	deacylase activity	7/2290	65/18639	0.107692307692308	0.876540141081626	0.70136376949879	0.999999999920195
GO:0004857	enzyme inhibitor activity	48/2290	416/18639	0.115384615384615	0.939150151158885	0.702760863642179	0.999999999920195
GO:0000146	microfilament motor activity	4/2290	38/18639	0.105263157894737	0.856768558951965	0.703045147723543	0.999999999920195
GO:0005109	frizzled binding	4/2290	38/18639	0.105263157894737	0.856768558951965	0.703045147723543	0.999999999920195
GO:0019955	cytokine binding	16/2290	144/18639	0.111111111111111	0.904366812227074	0.704106235471749	0.999999999920195
GO:0004519	endonuclease activity	14/2290	127/18639	0.110236220472441	0.897245813705601	0.707833943074619	0.999999999920195
GO:0004629	phospholipase C activity	3/2290	29/18639	0.103448275862069	0.841996687245897	0.709239349911522	0.999999999920195
GO:0005416	amino acid:monoatomic cation symporter activity	3/2290	29/18639	0.103448275862069	0.841996687245897	0.709239349911522	0.999999999920195
GO:0035250	UDP-galactosyltransferase activity	3/2290	29/18639	0.103448275862069	0.841996687245897	0.709239349911522	0.999999999920195
GO:0016779	nucleotidyltransferase activity	15/2290	136/18639	0.110294117647059	0.897717056254816	0.71120335078249	0.999999999920195
GO:0070279	vitamin B6 binding	6/2290	57/18639	0.105263157894737	0.856768558951965	0.716864963981341	0.999999999920195
GO:0016879	ligase activity, forming carbon-nitrogen bonds	5/2290	48/18639	0.104166666666667	0.847843886462882	0.718527461769697	0.999999999920195
GO:0038187	pattern recognition receptor activity	5/2290	48/18639	0.104166666666667	0.847843886462882	0.718527461769697	0.999999999920195
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/2290	39/18639	0.102564102564103	0.834800134363453	0.722611543013739	0.999999999920195
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/2290	39/18639	0.102564102564103	0.834800134363453	0.722611543013739	0.999999999920195
GO:0030742	GTP-dependent protein binding	2/2290	20/18639	0.1	0.813930131004367	0.72390005590145	0.999999999920195
GO:0042288	MHC class I protein binding	2/2290	20/18639	0.1	0.813930131004367	0.72390005590145	0.999999999920195
GO:0061608	nuclear import signal receptor activity	2/2290	20/18639	0.1	0.813930131004367	0.72390005590145	0.999999999920195
GO:0000182	rDNA binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0001094	TFIID-class transcription factor complex binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0004935	adrenergic receptor activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0004955	prostaglandin receptor activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0005031	tumor necrosis factor receptor activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0005337	nucleoside transmembrane transporter activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0005381	iron ion transmembrane transporter activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0008140	cAMP response element binding protein binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0008190	eukaryotic initiation factor 4E binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0008401	retinoic acid 4-hydroxylase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0008519	ammonium channel activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0015187	glycine transmembrane transporter activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0016427	tRNA (cytidine) methyltransferase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0019531	oxalate transmembrane transporter activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0031720	haptoglobin binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0031996	thioesterase binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0032356	oxidized DNA binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0043295	glutathione binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0047429	nucleoside triphosphate diphosphatase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0051864	histone H3K36 demethylase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0070739	protein-glutamic acid ligase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0070740	tubulin-glutamic acid ligase activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0097177	mitochondrial ribosome binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0098505	G-rich strand telomeric DNA binding	1/2290	10/18639	0.1	0.813930131004367	0.730512307042011	0.999999999920195
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/2290	30/18639	0.1	0.813930131004367	0.731109879544163	0.999999999920195
GO:0033612	receptor serine/threonine kinase binding	3/2290	30/18639	0.1	0.813930131004367	0.731109879544163	0.999999999920195
GO:0140098	catalytic activity, acting on RNA	44/2290	387/18639	0.113695090439276	0.925398598557936	0.732979564937387	0.999999999920195
GO:0005253	monoatomic anion channel activity	11/2290	103/18639	0.106796116504854	0.869245770975537	0.734371573269832	0.999999999920195
GO:0050997	quaternary ammonium group binding	4/2290	40/18639	0.1	0.813930131004367	0.741203300388	0.999999999920195
GO:0004867	serine-type endopeptidase inhibitor activity	10/2290	95/18639	0.105263157894737	0.856768558951965	0.745003648569107	0.999999999920195
GO:0070888	E-box binding	6/2290	59/18639	0.101694915254237	0.827725556953593	0.747812171971649	0.999999999920195
GO:0015174	basic amino acid transmembrane transporter activity	2/2290	21/18639	0.0952380952380952	0.775171553337492	0.748921932840399	0.999999999920195
GO:0036122	BMP binding	2/2290	21/18639	0.0952380952380952	0.775171553337492	0.748921932840399	0.999999999920195
GO:1904047	S-adenosyl-L-methionine binding	2/2290	21/18639	0.0952380952380952	0.775171553337492	0.748921932840399	0.999999999920195
GO:0032813	tumor necrosis factor receptor superfamily binding	5/2290	50/18639	0.1	0.813930131004367	0.751848079482257	0.999999999920195
GO:0015175	neutral L-amino acid transmembrane transporter activity	4/2290	41/18639	0.0975609756097561	0.794078176589626	0.758832108565501	0.999999999920195
GO:0017080	sodium channel regulator activity	4/2290	41/18639	0.0975609756097561	0.794078176589626	0.758832108565501	0.999999999920195
GO:0030246	carbohydrate binding	31/2290	280/18639	0.110714285714286	0.901136930754835	0.75945093320668	0.999999999920195
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	6/2290	60/18639	0.1	0.813930131004367	0.762336267830227	0.999999999920195
GO:0002162	dystroglycan binding	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0003953	NAD+ nucleosidase activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0004954	prostanoid receptor activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0005225	volume-sensitive anion channel activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0008526	phosphatidylinositol transfer activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0015217	ADP transmembrane transporter activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0019107	myristoyltransferase activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0019206	nucleoside kinase activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0019864	IgG binding	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0032404	mismatch repair complex binding	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0032794	GTPase activating protein binding	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0035252	UDP-xylosyltransferase activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0042285	xylosyltransferase activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0042608	T cell receptor binding	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0043522	leucine zipper domain binding	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0047676	arachidonate-CoA ligase activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0140031	phosphorylation-dependent protein binding	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0180030	inositol phosphate kinase activity	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:1900750	oligopeptide binding	1/2290	11/18639	0.0909090909090909	0.739936482731243	0.76363951821136	0.999999999920195
GO:0005272	sodium channel activity	5/2290	51/18639	0.0980392156862745	0.797970716670948	0.767365910499745	0.999999999920195
GO:0008378	galactosyltransferase activity	3/2290	32/18639	0.09375	0.763059497816594	0.770932852566772	0.999999999920195
GO:0042910	xenobiotic transmembrane transporter activity	3/2290	32/18639	0.09375	0.763059497816594	0.770932852566772	0.999999999920195
GO:0020037	heme binding	15/2290	142/18639	0.105633802816901	0.8597853496525	0.771046111601652	0.999999999920195
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/2290	22/18639	0.0909090909090909	0.739936482731243	0.771966170295211	0.999999999920195
GO:0016782	transferase activity, transferring sulphur-containing groups	7/2290	70/18639	0.1	0.813930131004367	0.772425636784478	0.999999999920195
GO:0031406	carboxylic acid binding	20/2290	187/18639	0.106951871657754	0.870513509095579	0.778492004494633	0.999999999920195
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/2290	33/18639	0.0909090909090909	0.739936482731243	0.788961209386143	0.999999999920195
GO:0008083	growth factor activity	17/2290	162/18639	0.104938271604938	0.854124211547792	0.790585457321025	0.999999999920195
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0003995	acyl-CoA dehydrogenase activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0004000	adenosine deaminase activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0004126	cytidine deaminase activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0004859	phospholipase inhibitor activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0004875	complement receptor activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0016801	hydrolase activity, acting on ether bonds	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0016803	ether hydrolase activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0035251	UDP-glucosyltransferase activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0097371	MDM2/MDM4 family protein binding	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0097677	STAT family protein binding	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0140900	chloride:bicarbonate antiporter activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:1990459	transferrin receptor binding	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:1990817	poly(A) RNA polymerase activity	1/2290	12/18639	0.0833333333333333	0.678275109170306	0.792696073037213	0.999999999920195
GO:0005283	amino acid:sodium symporter activity	2/2290	23/18639	0.0869565217391304	0.707765331308145	0.793140789945944	0.999999999920195
GO:0033192	calmodulin-dependent protein phosphatase activity	8/2290	81/18639	0.0987654320987654	0.80388161086851	0.793563618425855	0.999999999920195
GO:0140791	histone H2AXS140 phosphatase activity	8/2290	81/18639	0.0987654320987654	0.80388161086851	0.793563618425855	0.999999999920195
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	8/2290	81/18639	0.0987654320987654	0.80388161086851	0.793563618425855	0.999999999920195
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	8/2290	81/18639	0.0987654320987654	0.80388161086851	0.793563618425855	0.999999999920195
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	8/2290	81/18639	0.0987654320987654	0.80388161086851	0.793563618425855	0.999999999920195
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	8/2290	81/18639	0.0987654320987654	0.80388161086851	0.793563618425855	0.999999999920195
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	8/2290	81/18639	0.0987654320987654	0.80388161086851	0.793563618425855	0.999999999920195
GO:1990439	MAP kinase serine/threonine phosphatase activity	8/2290	81/18639	0.0987654320987654	0.80388161086851	0.793563618425855	0.999999999920195
GO:0043177	organic acid binding	20/2290	189/18639	0.105820105820106	0.861301725930547	0.793956850302377	0.999999999920195
GO:0005246	calcium channel regulator activity	5/2290	53/18639	0.0943396226415094	0.767858614155063	0.796166870285729	0.999999999920195
GO:0008194	UDP-glycosyltransferase activity	15/2290	145/18639	0.103448275862069	0.841996687245897	0.79757012075014	0.999999999920195
GO:0033549	MAP kinase phosphatase activity	8/2290	82/18639	0.0975609756097561	0.794078176589626	0.80462808287221	0.999999999920195
GO:0008175	tRNA methyltransferase activity	3/2290	34/18639	0.0882352941176471	0.718173645003853	0.805793720773148	0.999999999920195
GO:0015020	glucuronosyltransferase activity	3/2290	34/18639	0.0882352941176471	0.718173645003853	0.805793720773148	0.999999999920195
GO:0016831	carboxy-lyase activity	3/2290	34/18639	0.0882352941176471	0.718173645003853	0.805793720773148	0.999999999920195
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/2290	34/18639	0.0882352941176471	0.718173645003853	0.805793720773148	0.999999999920195
GO:0019825	oxygen binding	3/2290	34/18639	0.0882352941176471	0.718173645003853	0.805793720773148	0.999999999920195
GO:0051427	hormone receptor binding	3/2290	34/18639	0.0882352941176471	0.718173645003853	0.805793720773148	0.999999999920195
GO:0052866	phosphatidylinositol phosphate phosphatase activity	3/2290	34/18639	0.0882352941176471	0.718173645003853	0.805793720773148	0.999999999920195
GO:0030547	signaling receptor inhibitor activity	4/2290	44/18639	0.0909090909090909	0.739936482731243	0.806129141027732	0.999999999920195
GO:0004521	RNA endonuclease activity	7/2290	73/18639	0.0958904109589041	0.780480947538434	0.80863972545697	0.999999999920195
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	5/2290	54/18639	0.0925925925925926	0.753639010189229	0.809478768905664	0.999999999920195
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	5/2290	54/18639	0.0925925925925926	0.753639010189229	0.809478768905664	0.999999999920195
GO:0005315	phosphate transmembrane transporter activity	2/2290	24/18639	0.0833333333333333	0.678275109170306	0.812557131123902	0.999999999920195
GO:0015295	solute:proton symporter activity	2/2290	24/18639	0.0833333333333333	0.678275109170306	0.812557131123902	0.999999999920195
GO:0070300	phosphatidic acid binding	2/2290	24/18639	0.0833333333333333	0.678275109170306	0.812557131123902	0.999999999920195
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	8/2290	83/18639	0.0963855421686747	0.784510969642763	0.815237614604626	0.999999999920195
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0004535	poly(A)-specific ribonuclease activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0005035	death receptor activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0008417	fucosyltransferase activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0017154	semaphorin receptor activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0019855	calcium channel inhibitor activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0030955	potassium ion binding	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0031432	titin binding	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0035325	Toll-like receptor binding	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0035673	oligopeptide transmembrane transporter activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0039706	co-receptor binding	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0043560	insulin receptor substrate binding	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0045159	myosin II binding	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0061459	L-arginine transmembrane transporter activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0070700	BMP receptor binding	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0071837	HMG box domain binding	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:1901338	catecholamine binding	1/2290	13/18639	0.0769230769230769	0.62610010077259	0.818181980201264	0.999999999920195
GO:0015171	amino acid transmembrane transporter activity	10/2290	102/18639	0.0980392156862745	0.797970716670948	0.819118554019321	0.999999999920195
GO:0051539	4 iron, 4 sulfur cluster binding	4/2290	45/18639	0.0888888888888889	0.723493449781659	0.820113076756609	0.999999999920195
GO:0000175	3'-5'-RNA exonuclease activity	3/2290	35/18639	0.0857142857142857	0.697654398003743	0.821479825495749	0.999999999920195
GO:0017018	myosin phosphatase activity	8/2290	84/18639	0.0952380952380952	0.775171553337492	0.825399415094258	0.999999999920195
GO:0015078	proton transmembrane transporter activity	19/2290	185/18639	0.102702702702703	0.835928242653133	0.828976878762343	0.999999999920195
GO:0000030	mannosyltransferase activity	2/2290	25/18639	0.08	0.651144104803493	0.830327406282786	0.999999999920195
GO:0015662	P-type ion transporter activity	2/2290	25/18639	0.08	0.651144104803493	0.830327406282786	0.999999999920195
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/2290	25/18639	0.08	0.651144104803493	0.830327406282786	0.999999999920195
GO:0140358	P-type transmembrane transporter activity	2/2290	25/18639	0.08	0.651144104803493	0.830327406282786	0.999999999920195
GO:0004175	endopeptidase activity	44/2290	405/18639	0.108641975308642	0.884269771955361	0.830632849814651	0.999999999920195
GO:0004180	carboxypeptidase activity	4/2290	46/18639	0.0869565217391304	0.707765331308145	0.833253837823919	0.999999999920195
GO:0004033	aldo-keto reductase (NADPH) activity	3/2290	36/18639	0.0833333333333333	0.678275109170306	0.836071434951769	0.999999999920195
GO:0016409	palmitoyltransferase activity	3/2290	36/18639	0.0833333333333333	0.678275109170306	0.836071434951769	0.999999999920195
GO:0051536	iron-sulfur cluster binding	7/2290	76/18639	0.0921052631578947	0.749672489082969	0.840244242553251	0.999999999920195
GO:0005347	ATP transmembrane transporter activity	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:0008174	mRNA methyltransferase activity	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:0008191	metalloendopeptidase inhibitor activity	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:0016530	metallochaperone activity	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:0031404	chloride ion binding	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:0046030	inositol trisphosphate phosphatase activity	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:1901612	cardiolipin binding	1/2290	14/18639	0.0714285714285714	0.581378665003119	0.84053585464232	0.999999999920195
GO:0099095	ligand-gated monoatomic anion channel activity	4/2290	47/18639	0.0851063829787234	0.692706494471802	0.84558302644496	0.999999999920195
GO:0001637	G protein-coupled chemoattractant receptor activity	2/2290	26/18639	0.0769230769230769	0.62610010077259	0.846562806622357	0.999999999920195
GO:0004529	DNA exonuclease activity	2/2290	26/18639	0.0769230769230769	0.62610010077259	0.846562806622357	0.999999999920195
GO:0004950	chemokine receptor activity	2/2290	26/18639	0.0769230769230769	0.62610010077259	0.846562806622357	0.999999999920195
GO:0019865	immunoglobulin binding	2/2290	26/18639	0.0769230769230769	0.62610010077259	0.846562806622357	0.999999999920195
GO:0043548	phosphatidylinositol 3-kinase binding	2/2290	26/18639	0.0769230769230769	0.62610010077259	0.846562806622357	0.999999999920195
GO:0008173	RNA methyltransferase activity	6/2290	67/18639	0.0895522388059701	0.728892654630776	0.846975298889297	0.999999999920195
GO:0019001	guanyl nucleotide binding	43/2290	400/18639	0.1075	0.874974890829694	0.847192623781041	0.999999999920195
GO:0032561	guanyl ribonucleotide binding	43/2290	400/18639	0.1075	0.874974890829694	0.847192623781041	0.999999999920195
GO:0019213	deacetylase activity	3/2290	37/18639	0.0810810810810811	0.659943349463	0.849622002690431	0.999999999920195
GO:0051540	metal cluster binding	7/2290	77/18639	0.0909090909090909	0.739936482731243	0.849803398952345	0.999999999920195
GO:0004497	monooxygenase activity	10/2290	106/18639	0.0943396226415094	0.767858614155063	0.853459417508605	0.999999999920195
GO:0016853	isomerase activity	18/2290	180/18639	0.1	0.813930131004367	0.854864491564482	0.999999999920195
GO:0008408	3'-5' exonuclease activity	5/2290	58/18639	0.0862068965517241	0.701663906038247	0.855903377377788	0.999999999920195
GO:0005548	phospholipid transporter activity	6/2290	68/18639	0.0882352941176471	0.718173645003853	0.856783754275603	0.999999999920195
GO:0000774	adenyl-nucleotide exchange factor activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0004089	carbonate dehydratase activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0004467	long-chain fatty acid-CoA ligase activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0004559	alpha-mannosidase activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0004953	icosanoid receptor activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0010181	FMN binding	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0015929	hexosaminidase activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0016846	carbon-sulfur lyase activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0030553	cGMP binding	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0031386	protein tag activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0033130	acetylcholine receptor binding	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0047372	monoacylglycerol lipase activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0048531	beta-1,3-galactosyltransferase activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0140161	monocarboxylate:sodium symporter activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0141047	molecular tag activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0141050	histone H3K deacetylase activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0141051	histone H4K deacetylase activity	1/2290	15/18639	0.0666666666666667	0.542620087336244	0.86014245291717	0.999999999920195
GO:0004364	glutathione transferase activity	2/2290	27/18639	0.0740740740740741	0.602911208151383	0.861372059669433	0.999999999920195
GO:0008395	steroid hydroxylase activity	2/2290	27/18639	0.0740740740740741	0.602911208151383	0.861372059669433	0.999999999920195
GO:0016405	CoA-ligase activity	2/2290	27/18639	0.0740740740740741	0.602911208151383	0.861372059669433	0.999999999920195
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/2290	27/18639	0.0740740740740741	0.602911208151383	0.861372059669433	0.999999999920195
GO:0005525	GTP binding	40/2290	378/18639	0.105820105820106	0.861301725930547	0.865119320296203	0.999999999920195
GO:0016835	carbon-oxygen lyase activity	7/2290	79/18639	0.0886075949367089	0.721203913548173	0.867533373333789	0.999999999920195
GO:0015103	inorganic anion transmembrane transporter activity	16/2290	165/18639	0.096969696969697	0.789265581579992	0.874479497364469	0.999999999920195
GO:0000049	tRNA binding	7/2290	80/18639	0.0875	0.712188864628821	0.875731550529832	0.999999999920195
GO:0003688	DNA replication origin binding	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0004708	MAP kinase kinase activity	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0008142	oxysterol binding	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0008296	3'-5'-DNA exonuclease activity	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0015923	mannosidase activity	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0022841	potassium ion leak channel activity	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0140328	floppase activity	1/2290	16/18639	0.0625	0.508706331877729	0.877339284039361	0.999999999920195
GO:0061135	endopeptidase regulator activity	18/2290	184/18639	0.0978260869565217	0.796235997721663	0.877780319571663	0.999999999920195
GO:0005126	cytokine receptor binding	28/2290	275/18639	0.101818181818182	0.828728860658992	0.879613576206523	0.999999999920195
GO:0001618	virus receptor activity	7/2290	81/18639	0.0864197530864197	0.703396409509947	0.883504192755884	0.999999999920195
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	5/2290	61/18639	0.0819672131147541	0.667155845085546	0.884175538741343	0.999999999920195
GO:0016836	hydro-lyase activity	5/2290	61/18639	0.0819672131147541	0.667155845085546	0.884175538741343	0.999999999920195
GO:0004181	metallocarboxypeptidase activity	2/2290	29/18639	0.0689655172413793	0.561331124830598	0.887128579135058	0.999999999920195
GO:0051861	glycolipid binding	2/2290	29/18639	0.0689655172413793	0.561331124830598	0.887128579135058	0.999999999920195
GO:0016830	carbon-carbon lyase activity	4/2290	51/18639	0.0784313725490196	0.638376573336758	0.887452535404193	0.999999999920195
GO:0140272	exogenous protein binding	7/2290	82/18639	0.0853658536585366	0.694818404515923	0.890865963011694	0.999999999920195
GO:0004550	nucleoside diphosphate kinase activity	1/2290	17/18639	0.0588235294117647	0.478782430002569	0.892422409182993	0.999999999920195
GO:0016805	dipeptidase activity	1/2290	17/18639	0.0588235294117647	0.478782430002569	0.892422409182993	0.999999999920195
GO:0045125	bioactive lipid receptor activity	1/2290	17/18639	0.0588235294117647	0.478782430002569	0.892422409182993	0.999999999920195
GO:0045236	CXCR chemokine receptor binding	1/2290	17/18639	0.0588235294117647	0.478782430002569	0.892422409182993	0.999999999920195
GO:0005319	lipid transporter activity	17/2290	178/18639	0.0955056179775281	0.777349001521024	0.894317380868481	0.999999999920195
GO:0001530	lipopolysaccharide binding	3/2290	41/18639	0.0731707317073171	0.59555863244222	0.894495996889056	0.999999999920195
GO:0015215	nucleotide transmembrane transporter activity	2/2290	30/18639	0.0666666666666667	0.542620087336244	0.898272771962979	0.999999999920195
GO:0070566	adenylyltransferase activity	2/2290	30/18639	0.0666666666666667	0.542620087336244	0.898272771962979	0.999999999920195
GO:0004722	protein serine/threonine phosphatase activity	9/2290	103/18639	0.087378640776699	0.711201085343621	0.899391644332685	0.999999999920195
GO:0005342	organic acid transmembrane transporter activity	18/2290	189/18639	0.0952380952380952	0.775171553337492	0.902308481361484	0.999999999920195
GO:0017046	peptide hormone binding	4/2290	53/18639	0.0754716981132075	0.61428689132405	0.904397381112551	0.999999999920195
GO:0004970	glutamate-gated receptor activity	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:0008525	phosphatidylcholine transporter activity	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:0016854	racemase and epimerase activity	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:0022851	GABA-gated chloride ion channel activity	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:0032393	MHC class I receptor activity	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:0050811	GABA receptor binding	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:1901611	phosphatidylglycerol binding	1/2290	18/18639	0.0555555555555556	0.452183406113537	0.905651529737764	0.999999999920195
GO:0005164	tumor necrosis factor receptor binding	2/2290	31/18639	0.0645161290322581	0.525116213551204	0.908383806731723	0.999999999920195
GO:0005452	solute:inorganic anion antiporter activity	2/2290	31/18639	0.0645161290322581	0.525116213551204	0.908383806731723	0.999999999920195
GO:0016878	acid-thiol ligase activity	2/2290	31/18639	0.0645161290322581	0.525116213551204	0.908383806731723	0.999999999920195
GO:0047499	calcium-independent phospholipase A2 activity	2/2290	31/18639	0.0645161290322581	0.525116213551204	0.908383806731723	0.999999999920195
GO:0072349	modified amino acid transmembrane transporter activity	2/2290	31/18639	0.0645161290322581	0.525116213551204	0.908383806731723	0.999999999920195
GO:0016829	lyase activity	19/2290	200/18639	0.095	0.773233624454148	0.909613736608619	0.999999999920195
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/2290	19/18639	0.0526315789473684	0.428384279475983	0.917254451004104	0.999999999920195
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/2290	19/18639	0.0526315789473684	0.428384279475983	0.917254451004104	0.999999999920195
GO:0004890	GABA-A receptor activity	1/2290	19/18639	0.0526315789473684	0.428384279475983	0.917254451004104	0.999999999920195
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/2290	19/18639	0.0526315789473684	0.428384279475983	0.917254451004104	0.999999999920195
GO:0022840	leak channel activity	1/2290	19/18639	0.0526315789473684	0.428384279475983	0.917254451004104	0.999999999920195
GO:0022842	narrow pore channel activity	1/2290	19/18639	0.0526315789473684	0.428384279475983	0.917254451004104	0.999999999920195
GO:0042834	peptidoglycan binding	1/2290	19/18639	0.0526315789473684	0.428384279475983	0.917254451004104	0.999999999920195
GO:0046527	glucosyltransferase activity	1/2290	19/18639	0.0526315789473684	0.428384279475983	0.917254451004104	0.999999999920195
GO:0015106	bicarbonate transmembrane transporter activity	2/2290	32/18639	0.0625	0.508706331877729	0.917547203676053	0.999999999920195
GO:0030515	snoRNA binding	2/2290	32/18639	0.0625	0.508706331877729	0.917547203676053	0.999999999920195
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/2290	32/18639	0.0625	0.508706331877729	0.917547203676053	0.999999999920195
GO:0047498	calcium-dependent phospholipase A2 activity	2/2290	32/18639	0.0625	0.508706331877729	0.917547203676053	0.999999999920195
GO:0099094	ligand-gated monoatomic cation channel activity	12/2290	136/18639	0.0882352941176471	0.718173645003853	0.919359988766773	0.999999999920195
GO:0022832	voltage-gated channel activity	16/2290	175/18639	0.0914285714285714	0.744164691203993	0.922265701969164	0.999999999920195
GO:0019239	deaminase activity	2/2290	33/18639	0.0606060606060606	0.493290988487495	0.925843074275402	0.999999999920195
GO:0001614	purinergic nucleotide receptor activity	1/2290	20/18639	0.05	0.406965065502183	0.92743099811477	0.999999999920195
GO:0005326	neurotransmitter transmembrane transporter activity	1/2290	20/18639	0.05	0.406965065502183	0.92743099811477	0.999999999920195
GO:0015095	magnesium ion transmembrane transporter activity	1/2290	20/18639	0.05	0.406965065502183	0.92743099811477	0.999999999920195
GO:0016502	nucleotide receptor activity	1/2290	20/18639	0.05	0.406965065502183	0.92743099811477	0.999999999920195
GO:0140223	general transcription initiation factor activity	5/2290	68/18639	0.0735294117647059	0.598478037503211	0.932244983657149	0.999999999920195
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/2290	34/18639	0.0588235294117647	0.478782430002569	0.933346158869293	0.999999999920195
GO:0090482	vitamin transmembrane transporter activity	2/2290	34/18639	0.0588235294117647	0.478782430002569	0.933346158869293	0.999999999920195
GO:0046943	carboxylic acid transmembrane transporter activity	17/2290	188/18639	0.0904255319148936	0.736000650376289	0.934751546322834	0.999999999920195
GO:0030414	peptidase inhibitor activity	15/2290	169/18639	0.0887573964497041	0.722423193199142	0.935243308213901	0.999999999920195
GO:0001846	opsonin binding	1/2290	21/18639	0.0476190476190476	0.387585776668746	0.936356451378489	0.999999999920195
GO:0019200	carbohydrate kinase activity	1/2290	21/18639	0.0476190476190476	0.387585776668746	0.936356451378489	0.999999999920195
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/2290	21/18639	0.0476190476190476	0.387585776668746	0.936356451378489	0.999999999920195
GO:0051428	peptide hormone receptor binding	1/2290	21/18639	0.0476190476190476	0.387585776668746	0.936356451378489	0.999999999920195
GO:0070182	DNA polymerase binding	1/2290	21/18639	0.0476190476190476	0.387585776668746	0.936356451378489	0.999999999920195
GO:0004623	phospholipase A2 activity	2/2290	35/18639	0.0571428571428571	0.465102932002495	0.940125936649507	0.999999999920195
GO:0005343	organic acid:sodium symporter activity	2/2290	35/18639	0.0571428571428571	0.465102932002495	0.940125936649507	0.999999999920195
GO:0016229	steroid dehydrogenase activity	2/2290	35/18639	0.0571428571428571	0.465102932002495	0.940125936649507	0.999999999920195
GO:0004866	endopeptidase inhibitor activity	14/2290	161/18639	0.0869565217391304	0.707765331308145	0.940824292793189	0.999999999920195
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	11/2290	132/18639	0.0833333333333333	0.678275109170306	0.942482608985917	0.999999999920195
GO:0015101	organic cation transmembrane transporter activity	6/2290	81/18639	0.0740740740740741	0.602911208151383	0.943320187680277	0.999999999920195
GO:0008649	rRNA methyltransferase activity	1/2290	22/18639	0.0454545454545455	0.369968241365621	0.944184560001502	0.999999999920195
GO:0008970	phospholipase A1 activity	1/2290	22/18639	0.0454545454545455	0.369968241365621	0.944184560001502	0.999999999920195
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/2290	22/18639	0.0454545454545455	0.369968241365621	0.944184560001502	0.999999999920195
GO:0022843	voltage-gated monoatomic cation channel activity	12/2290	143/18639	0.0839160839160839	0.683018291751916	0.94604873874101	0.999999999920195
GO:0004190	aspartic-type endopeptidase activity	2/2290	36/18639	0.0555555555555556	0.452183406113537	0.946246789690551	0.999999999920195
GO:0005244	voltage-gated monoatomic ion channel activity	15/2290	173/18639	0.0867052023121387	0.705719766766792	0.947745220702181	0.999999999920195
GO:0005267	potassium channel activity	10/2290	124/18639	0.0806451612903226	0.656395266939005	0.949303917672998	0.999999999920195
GO:0001664	G protein-coupled receptor binding	28/2290	297/18639	0.0942760942760943	0.767341537647214	0.949632789510994	0.999999999920195
GO:0000295	adenine nucleotide transmembrane transporter activity	1/2290	23/18639	0.0434782608695652	0.353882665654073	0.951050185913118	0.999999999920195
GO:0005212	structural constituent of eye lens	1/2290	23/18639	0.0434782608695652	0.353882665654073	0.951050185913118	0.999999999920195
GO:0008171	O-methyltransferase activity	1/2290	23/18639	0.0434782608695652	0.353882665654073	0.951050185913118	0.999999999920195
GO:0016493	C-C chemokine receptor activity	1/2290	23/18639	0.0434782608695652	0.353882665654073	0.951050185913118	0.999999999920195
GO:0016917	GABA receptor activity	1/2290	23/18639	0.0434782608695652	0.353882665654073	0.951050185913118	0.999999999920195
GO:0043274	phospholipase binding	1/2290	23/18639	0.0434782608695652	0.353882665654073	0.951050185913118	0.999999999920195
GO:0140102	catalytic activity, acting on a rRNA	1/2290	23/18639	0.0434782608695652	0.353882665654073	0.951050185913118	0.999999999920195
GO:0140103	catalytic activity, acting on a glycoprotein	1/2290	23/18639	0.0434782608695652	0.353882665654073	0.951050185913118	0.999999999920195
GO:0070001	aspartic-type peptidase activity	2/2290	37/18639	0.0540540540540541	0.439962232975333	0.951768206090558	0.999999999920195
GO:0048020	CCR chemokine receptor binding	3/2290	50/18639	0.06	0.48835807860262	0.954589109876867	0.999999999920195
GO:0042887	amide transmembrane transporter activity	2/2290	38/18639	0.0526315789473684	0.428384279475983	0.956745010144691	0.999999999920195
GO:0004622	lysophospholipase activity	1/2290	24/18639	0.0416666666666667	0.339137554585153	0.957071623077867	0.999999999920195
GO:0004806	triacylglycerol lipase activity	1/2290	24/18639	0.0416666666666667	0.339137554585153	0.957071623077867	0.999999999920195
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2290	24/18639	0.0416666666666667	0.339137554585153	0.957071623077867	0.999999999920195
GO:0019957	C-C chemokine binding	1/2290	24/18639	0.0416666666666667	0.339137554585153	0.957071623077867	0.999999999920195
GO:0005251	delayed rectifier potassium channel activity	1/2290	25/18639	0.04	0.325572052401747	0.962352632110995	0.999999999920195
GO:0008139	nuclear localization sequence binding	1/2290	25/18639	0.04	0.325572052401747	0.962352632110995	0.999999999920195
GO:0015645	fatty acid ligase activity	1/2290	25/18639	0.04	0.325572052401747	0.962352632110995	0.999999999920195
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2290	25/18639	0.04	0.325572052401747	0.962352632110995	0.999999999920195
GO:0017056	structural constituent of nuclear pore	1/2290	25/18639	0.04	0.325572052401747	0.962352632110995	0.999999999920195
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/2290	25/18639	0.04	0.325572052401747	0.962352632110995	0.999999999920195
GO:0019707	protein-cysteine S-acyltransferase activity	1/2290	25/18639	0.04	0.325572052401747	0.962352632110995	0.999999999920195
GO:0120515	fatty acid-CoA ligase activity	1/2290	25/18639	0.04	0.325572052401747	0.962352632110995	0.999999999920195
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/2290	52/18639	0.0576923076923077	0.469575075579442	0.962615111400304	0.999999999920195
GO:0016757	glycosyltransferase activity	24/2290	267/18639	0.0898876404494382	0.731622589666847	0.964279361632202	0.999999999920195
GO:0015079	potassium ion transmembrane transporter activity	13/2290	160/18639	0.08125	0.661318231441048	0.964519332976373	0.999999999920195
GO:0071855	neuropeptide receptor binding	2/2290	40/18639	0.05	0.406965065502183	0.965262254002911	0.999999999920195
GO:0016251	RNA polymerase II general transcription initiation factor activity	3/2290	53/18639	0.0566037735849057	0.460715168493038	0.966108175217569	0.999999999920195
GO:0016860	intramolecular oxidoreductase activity	3/2290	53/18639	0.0566037735849057	0.460715168493038	0.966108175217569	0.999999999920195
GO:0019843	rRNA binding	4/2290	65/18639	0.0615384615384615	0.500880080618072	0.966153933460375	0.999999999920195
GO:0008066	glutamate receptor activity	1/2290	26/18639	0.0384615384615385	0.313050050386295	0.966984225130541	0.999999999920195
GO:0015216	purine nucleotide transmembrane transporter activity	1/2290	26/18639	0.0384615384615385	0.313050050386295	0.966984225130541	0.999999999920195
GO:0120014	phospholipid transfer activity	1/2290	26/18639	0.0384615384615385	0.313050050386295	0.966984225130541	0.999999999920195
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/2290	41/18639	0.0487804878048781	0.397039088294813	0.968891292829263	0.999999999920195
GO:0042287	MHC protein binding	2/2290	41/18639	0.0487804878048781	0.397039088294813	0.968891292829263	0.999999999920195
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	9/2290	122/18639	0.0737704918032787	0.600440260576992	0.970966454701679	0.999999999920195
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/2290	27/18639	0.037037037037037	0.301455604075691	0.97104623149443	0.999999999920195
GO:0015252	proton channel activity	1/2290	27/18639	0.037037037037037	0.301455604075691	0.97104623149443	0.999999999920195
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/2290	27/18639	0.037037037037037	0.301455604075691	0.97104623149443	0.999999999920195
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	4/2290	67/18639	0.0597014925373134	0.485928436420518	0.971774652154262	0.999999999920195
GO:0005242	inward rectifier potassium channel activity	1/2290	28/18639	0.0357142857142857	0.29068933250156	0.974608671311631	0.999999999920195
GO:0005261	monoatomic cation channel activity	31/2290	341/18639	0.0909090909090909	0.739936482731243	0.974910996553973	0.999999999920195
GO:0015276	ligand-gated monoatomic ion channel activity	15/2290	186/18639	0.0806451612903226	0.656395266939005	0.975074097211459	0.999999999920195
GO:0008375	acetylglucosaminyltransferase activity	2/2290	43/18639	0.0465116279069767	0.378572153955519	0.975084013921934	0.999999999920195
GO:0015297	antiporter activity	10/2290	135/18639	0.0740740740740741	0.602911208151383	0.975536617585815	0.999999999920195
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3/2290	57/18639	0.0526315789473684	0.428384279475983	0.977227922963791	0.999999999920195
GO:0003785	actin monomer binding	1/2290	29/18639	0.0344827586206897	0.280665562415299	0.977732960317937	0.999999999920195
GO:0016417	S-acyltransferase activity	1/2290	29/18639	0.0344827586206897	0.280665562415299	0.977732960317937	0.999999999920195
GO:0022834	ligand-gated channel activity	15/2290	188/18639	0.0797872340425532	0.649412338567314	0.97787990266685	0.999999999920195
GO:0022804	active transmembrane transporter activity	43/2290	457/18639	0.0940919037199125	0.765842355211986	0.978605901272045	0.999999999920195
GO:0015294	solute:monoatomic cation symporter activity	8/2290	116/18639	0.0689655172413793	0.561331124830598	0.979391754239286	0.999999999920195
GO:0042605	peptide antigen binding	2/2290	45/18639	0.0444444444444444	0.36174672489083	0.980076317305961	0.999999999920195
GO:0042379	chemokine receptor binding	4/2290	72/18639	0.0555555555555556	0.452183406113537	0.982236014421845	0.999999999920195
GO:0004896	cytokine receptor activity	6/2290	96/18639	0.0625	0.508706331877729	0.982844484630445	0.999999999920195
GO:0016798	hydrolase activity, acting on glycosyl bonds	9/2290	130/18639	0.0692307692307692	0.563490090695331	0.983663621311577	0.999999999920195
GO:0043495	protein-membrane adaptor activity	2/2290	47/18639	0.0425531914893617	0.346353247235901	0.984092254441452	0.999999999920195
GO:0005249	voltage-gated potassium channel activity	6/2290	98/18639	0.0612244897959184	0.498324570002674	0.98549352670982	0.999999999920195
GO:0003735	structural constituent of ribosome	13/2290	175/18639	0.0742857142857143	0.604633811603244	0.986238472072395	0.999999999920195
GO:0042923	neuropeptide binding	1/2290	33/18639	0.0303030303030303	0.246645494243748	0.986831449965193	0.999999999920195
GO:0016758	hexosyltransferase activity	15/2290	197/18639	0.0761421319796954	0.619743754571853	0.987294852066799	0.999999999920195
GO:0016874	ligase activity	12/2290	167/18639	0.0718562874251497	0.584859974374395	0.988393922827738	0.999999999920195
GO:0015605	organophosphate ester transmembrane transporter activity	2/2290	50/18639	0.04	0.325572052401747	0.988680067669495	0.999999999920195
GO:0015293	symporter activity	10/2290	146/18639	0.0684931506849315	0.557486391098881	0.988787130416157	0.999999999920195
GO:0003730	mRNA 3'-UTR binding	21/2290	262/18639	0.0801526717557252	0.652386746224874	0.990006076308479	0.999999999920195
GO:0005216	monoatomic ion channel activity	40/2290	448/18639	0.0892857142857143	0.726723331253899	0.990561862760045	0.999999999920195
GO:0015370	solute:sodium symporter activity	4/2290	79/18639	0.0506329113924051	0.412116522027528	0.990889058214531	0.999999999920195
GO:0046873	metal ion transmembrane transporter activity	40/2290	450/18639	0.0888888888888889	0.723493449781659	0.991379899630271	0.999999999920195
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/2290	53/18639	0.0377358490566038	0.307143445662025	0.991967498364362	0.999999999920195
GO:0023023	MHC protein complex binding	1/2290	37/18639	0.027027027027027	0.219981116487667	0.992213164157391	0.999999999920195
GO:0030551	cyclic nucleotide binding	1/2290	37/18639	0.027027027027027	0.219981116487667	0.992213164157391	0.999999999920195
GO:0022836	gated channel activity	26/2290	318/18639	0.0817610062893082	0.665477465601055	0.992882346511687	0.999999999920195
GO:0046982	protein heterodimerization activity	31/2290	369/18639	0.0840108401084011	0.683789540952178	0.993499048143001	0.999999999920195
GO:0005179	hormone activity	8/2290	132/18639	0.0606060606060606	0.493290988487495	0.994123274890329	0.999999999920195
GO:0170055	lipid transmembrane transporter activity	2/2290	56/18639	0.0357142857142857	0.29068933250156	0.994314792144166	0.999999999920195
GO:0004620	phospholipase activity	6/2290	109/18639	0.055045871559633	0.448034934497817	0.994403034489475	0.999999999920195
GO:0140662	ATP-dependent protein folding chaperone	1/2290	40/18639	0.025	0.203482532751092	0.994749581714276	0.999999999920195
GO:0004812	aminoacyl-tRNA ligase activity	1/2290	41/18639	0.024390243902439	0.198519544147407	0.995396038936401	0.999999999920195
GO:0008227	G protein-coupled amine receptor activity	1/2290	41/18639	0.024390243902439	0.198519544147407	0.995396038936401	0.999999999920195
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/2290	41/18639	0.024390243902439	0.198519544147407	0.995396038936401	0.999999999920195
GO:0044183	protein folding chaperone	3/2290	75/18639	0.04	0.325572052401747	0.996503277391896	0.999999999920195
GO:0015081	sodium ion transmembrane transporter activity	10/2290	164/18639	0.0609756097560976	0.496298860368516	0.997155387443538	0.999999999920195
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	4/2290	91/18639	0.043956043956044	0.357771486155766	0.997225076814693	0.999999999920195
GO:0016298	lipase activity	7/2290	130/18639	0.0538461538461538	0.438270070540813	0.997445020820318	0.999999999920195
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	7/2290	130/18639	0.0538461538461538	0.438270070540813	0.997445020820318	0.999999999920195
GO:0022824	transmitter-gated monoatomic ion channel activity	2/2290	63/18639	0.0317460317460317	0.258390517779164	0.997483946896099	0.999999999920195
GO:0022835	transmitter-gated channel activity	2/2290	63/18639	0.0317460317460317	0.258390517779164	0.997483946896099	0.999999999920195
GO:0008514	organic anion transmembrane transporter activity	19/2290	269/18639	0.0706319702602231	0.574894888069999	0.998189691072891	0.999999999920195
GO:0008528	G protein-coupled peptide receptor activity	6/2290	122/18639	0.0491803278688525	0.400293507051328	0.99828410960292	0.999999999920195
GO:0008236	serine-type peptidase activity	12/2290	194/18639	0.0618556701030928	0.503461936703732	0.998382437410378	0.999999999920195
GO:0016597	amino acid binding	1/2290	51/18639	0.0196078431372549	0.15959414333419	0.998763116991686	0.999999999920195
GO:0017171	serine hydrolase activity	12/2290	198/18639	0.0606060606060606	0.493290988487495	0.99881378105528	0.999999999920195
GO:0004252	serine-type endopeptidase activity	10/2290	176/18639	0.0568181818181818	0.462460301707027	0.998922559195054	0.999999999920195
GO:0001653	peptide receptor activity	6/2290	128/18639	0.046875	0.381529748908297	0.999023247146871	0.999999999920195
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/2290	53/18639	0.0188679245283019	0.153571722831013	0.999049113591812	0.999999999920195
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/2290	73/18639	0.0273972602739726	0.222994556439553	0.999228488864916	0.999999999920195
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/2290	56/18639	0.0178571428571429	0.14534466625078	0.999359079685036	0.999999999920195
GO:0052689	carboxylic ester hydrolase activity	3/2290	92/18639	0.0326086956521739	0.265411999240554	0.999456472289395	0.999999999920195
GO:0015291	secondary active transmembrane transporter activity	19/2290	287/18639	0.0662020905923345	0.538838762685818	0.999471203670999	0.999999999920195
GO:0140375	immune receptor activity	7/2290	156/18639	0.0448717948717949	0.365225058784011	0.999764620536522	0.999999999920195
GO:0098960	postsynaptic neurotransmitter receptor activity	1/2290	69/18639	0.0144927536231884	0.117960888551358	0.999884107401228	0.999999999920195
GO:0030594	neurotransmitter receptor activity	2/2290	97/18639	0.0206185567010309	0.167820645567911	0.999957465381309	0.999999999920195
GO:0140101	catalytic activity, acting on a tRNA	4/2290	139/18639	0.0287769784172662	0.234224498130753	0.999983599798953	0.999999999920195
GO:0005125	cytokine activity	10/2290	234/18639	0.0427350427350427	0.347833389318105	0.999993892027851	0.999999999920195
GO:0003823	antigen binding	4/2290	174/18639	0.0229885057471264	0.187110374943533	0.999999692927313	0.999999999920195
GO:0045182	translation regulator activity	13/2290	356/18639	0.0365168539325843	0.297221677052156	0.999999997744696	0.999999999920195
GO:0030371	translation repressor activity	9/2290	329/18639	0.027355623100304	0.222655658937365	0.999999999920195	0.999999999920195