category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	7/30	222/9376	9.85465465465465	RPS27/RPS26/RPS29/RPL21/RPL10/RPL18A/RPL41	7.56442703456215
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	7/30	238/9376	9.1921568627451	RPS27/RPS26/RPS29/RPL21/RPL10/RPL18A/RPL41	7.25261357343678
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	4/30	134/9376	9.32935323383085	MYL6/RAMP1/GNAS/MYL9	5.50191750662927
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/30	82/9376	11.4341463414634	B2M/HLA-B/CD74	5.37645348554811
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/30	154/9376	6.08831168831169	MYL6/GNAS/MYL9	3.6070726138937
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/30	170/9376	5.51529411764706	TUBA1B/MYL6/MYL9	3.36595571137692
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/30	180/9376	5.20888888888889	B2M/HLA-B/CD74	3.23026096505453
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/30	194/9376	4.83298969072165	TUBA1B/MYL6/MYL9	3.05635114609807
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/30	75/9376	8.33422222222222	GSTP1/TOP2A	3.61287762458668
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/30	204/9376	4.59607843137255	IGF2/LUM/COL1A1	2.94201981288393
NA	NA	hsa04081	Hormone signaling	3/30	219/9376	4.28127853881278	IGF2/RAMP1/GNAS	2.78369677033196
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/30	89/9376	7.02322097378277	TUBA1B/GNAS	3.23459159848844
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	3/30	227/9376	4.13039647577093	B2M/HLA-B/GNAS	2.70494748517508
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	3/30	233/9376	4.02403433476395	COL1A1/MYL9/COL5A1	2.64821777143799
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/30	103/9376	6.06860841423948	COL1A1/COL5A1	2.9304249268841
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/30	103/9376	6.06860841423948	COL1A1/GNAS	2.9304249268841
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/30	248/9376	3.78064516129032	TUBA1B/MYL9/GAPDH	2.51429929681425
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	3/30	268/9376	3.49850746268657	TUBA1B/GNAS/UBC	2.35109357257967
Organismal Systems	Immune system	hsa04611	Platelet activation	2/30	126/9376	4.96084656084656	COL1A1/GNAS	2.5359214782321
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/30	130/9376	4.80820512820513	COL1A1/GNAS	2.47712796573447
NA	NA	hsa04517	IgSF CAM signaling	3/30	299/9376	3.13578595317726	TUBA1B/MYL6/MYL9	2.12645173374129
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/30	139/9376	4.4968824940048	GNAS/KRT19	2.35318647962141
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/30	155/9376	4.03268817204301	TUBA1B/HLA-B	2.15693954466868
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/30	333/9376	2.81561561561562	HLA-B/COL1A1/GNAS	1.91127481839978
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/30	170/9376	3.67686274509804	IGF2/GSTP1	1.99548494752986
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/30	37/9376	8.44684684684685	HBB	2.57132204786564
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/30	39/9376	8.01367521367521	HLA-B	2.48660986465192
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	3/30	388/9376	2.41649484536082	TUBA1B/APOE/GAPDH	1.6144801382976
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/30	196/9376	3.1891156462585	HLA-B/UBC	1.7547238431533
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/30	44/9376	7.1030303030303	HLA-B	2.29888833578874
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/30	44/9376	7.1030303030303	GNAS	2.29888833578874
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	2/30	200/9376	3.12533333333333	TUBA1B/GAPDH	1.72126891706951
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/30	45/9376	6.94518518518518	HLA-B	2.26485772928101
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/30	203/9376	3.07914614121511	COL1A1/MYL9	1.696722097489
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/30	205/9376	3.04910569105691	B2M/HLA-B	1.68060758977377
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/30	205/9376	3.04910569105691	COL1A1/GAPDH	1.68060758977377
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/30	49/9376	6.37823129251701	GNAS	2.13845395797284
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/30	50/9376	6.25066666666667	CKB	2.10904148406304
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/30	50/9376	6.25066666666667	HBB	2.10904148406304
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/30	214/9376	2.9208722741433	B2M/HLA-B	1.6104365112197
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/30	51/9376	6.1281045751634	GNAS	2.08041951048335
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/30	52/9376	6.01025641025641	GNAS	2.05255058441948
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/30	52/9376	6.01025641025641	APOE	2.05255058441948
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/30	53/9376	5.89685534591195	GNAS	2.02539971702731
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/30	54/9376	5.78765432098765	HLA-B	1.99893417811932
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/30	224/9376	2.79047619047619	B2M/HLA-B	1.53662512816219
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/30	226/9376	2.76578171091445	GNAS/MYL9	1.52234843133926
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/30	59/9376	5.29717514124294	GSTP1	1.87587713574898
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/30	59/9376	5.29717514124294	GNAS	1.87587713574898
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/30	60/9376	5.20888888888889	GNAS	1.85294156454214
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/30	65/9376	4.80820512820513	GNAS	1.74546934447167
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/30	253/9376	2.47061923583663	MYL9/UBC	1.34346093521072
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/30	67/9376	4.66467661691542	GAPDH	1.70551255394648
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/30	68/9376	4.59607843137255	ALDH1A2	1.68612124886079
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/30	69/9376	4.52946859903382	GNAS	1.66710282732054
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/30	69/9376	4.52946859903382	GNAS	1.66710282732054
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/30	70/9376	4.4647619047619	GSTP1	1.6484442681894
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/30	70/9376	4.4647619047619	HLA-B	1.6484442681894
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/30	73/9376	4.28127853881278	GSTP1	1.59450687024501
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/30	73/9376	4.28127853881278	PPIA	1.59450687024501
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/30	75/9376	4.16711111111111	GAPDH	1.56013610185461
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/30	75/9376	4.16711111111111	GNAS	1.56013610185461
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/30	76/9376	4.11228070175439	UBC	1.54339631466192
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/30	76/9376	4.11228070175439	GNAS	1.54339631466192
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/30	79/9376	3.95611814345992	GSTP1	1.49484889365203
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/30	82/9376	3.81138211382114	GSTP1	1.44863457636165
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/30	86/9376	3.63410852713178	GNAS	1.39029963925308
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/30	89/9376	3.51161048689139	COL1A1	1.34878567712122
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/30	90/9376	3.47259259259259	GNAS	1.33534306756048
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/30	91/9376	3.43443223443223	GNAS	1.32208935738486
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/30	93/9376	3.36057347670251	MYL9	1.29612891523851
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/30	93/9376	3.36057347670251	GNAS	1.29612891523851
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/30	93/9376	3.36057347670251	GNAS	1.29612891523851
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/30	97/9376	3.22199312714777	GNAS	1.24626778289458
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/30	98/9376	3.1891156462585	GNAS	1.23420680314434
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/30	99/9376	3.15690235690236	GNAS	1.22229963261595
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/30	99/9376	3.15690235690236	GNAS	1.22229963261595
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/30	99/9376	3.15690235690236	KRT19	1.22229963261595
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/30	101/9376	3.09438943894389	GNAS	1.19893197893947
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/30	101/9376	3.09438943894389	COL1A1	1.19893197893947
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/30	102/9376	3.0640522875817	GNAS	1.18746443762579
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/30	103/9376	3.03430420711974	GNAS	1.17613657836761
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/30	105/9376	2.97650793650794	UBC	1.15388704853622
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/30	105/9376	2.97650793650794	GNAS	1.15388704853622
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/30	106/9376	2.94842767295597	GSTP1	1.14295921088246
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/30	107/9376	2.9208722741433	GNAS	1.13215871237936
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/30	110/9376	2.84121212121212	GAPDH	1.10049328565519
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/30	115/9376	2.71768115942029	GNAS	1.05001597708468
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/30	115/9376	2.71768115942029	GNAS	1.05001597708468
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/30	116/9376	2.69425287356322	GAPDH	1.04024373622943
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/30	116/9376	2.69425287356322	MYL9	1.04024373622943
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/30	116/9376	2.69425287356322	GNAS	1.04024373622943
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	2/30	362/9376	1.72670349907919	IGF2/COL1A1	0.798888440045779
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/30	122/9376	2.56174863387978	GNAS	0.983693223679115
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/30	133/9376	2.34987468671679	HLA-B	0.88827241319952
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/30	133/9376	2.34987468671679	GNAS	0.88827241319952
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/30	137/9376	2.28126520681265	TUBA1B	0.855894449814136
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/30	142/9376	2.20093896713615	UBC	0.816965187918098
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/30	142/9376	2.20093896713615	GSTP1	0.816965187918098
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/30	149/9376	2.09753914988814	GNAS	0.765096599718614
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/30	154/9376	2.02943722943723	GNAS	0.72976167056655
NA	NA	hsa04518	Integrin signaling	1/30	154/9376	2.02943722943723	COL1A1	0.72976167056655
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/30	155/9376	2.01634408602151	GNAS	0.722854650978881
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/30	157/9376	1.99065817409766	HLA-B	0.709194115258733
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/30	160/9376	1.95333333333333	HLA-B	0.689075666621653
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/30	166/9376	1.88273092369478	MYL9	0.650108653831451
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/30	168/9376	1.86031746031746	PPIA	0.637476383054397
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/30	169/9376	1.84930966469428	UBC	0.631224321379275
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/30	178/9376	1.75580524344569	SFRP4	0.576775197122135
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/30	181/9376	1.72670349907919	CD74	0.559311886673652
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/30	184/9376	1.69855072463768	MYL9	0.542169682128268
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	2/30	480/9376	1.30222222222222	TUBA1B/UBC	0.385108410467479
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/30	191/9376	1.63630017452007	GNAS	0.503352839483593
NA	NA	hsa04082	Neuroactive ligand signaling	1/30	199/9376	1.57051926298157	GNAS	0.460871510192476
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/30	205/9376	1.52455284552846	HLA-B	0.430220606618804
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/30	212/9376	1.47421383647799	GNAS	0.395669877911856
NA	NA	hsa04382	Cornified envelope formation	1/30	217/9376	1.44024577572965	KRT19	0.371735820802104
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/30	217/9376	1.44024577572965	GNAS	0.371735820802104
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/30	232/9376	1.34712643678161	MYL9	0.303317139278716
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/30	235/9376	1.32992907801418	GNAS	0.290195749666077
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/30	238/9376	1.31316526610644	IGF2	0.277248922078312
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/30	250/9376	1.25013333333333	HLA-B	0.227109196082907
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/30	254/9376	1.23044619422572	GNAS	0.210947674377627
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	1/30	275/9376	1.13648484848485	TUBA1B	0.130148632401043
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/30	300/9376	1.04177777777778	IGF2	0.0416669869353107
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	1/30	308/9376	1.01471861471861	TUBA1B	0.0148805819826263
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/30	368/9376	0.84927536231884	TUBA1B	-0.167119584172336
NA	NA	hsa04519	Cadherin signaling	1/30	404/9376	0.773597359735974	KRT19	-0.263548721965897