ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0019838 growth factor binding 5/35 136/18639 0.0367647058823529 19.578781512605 5.22997546772758e-06 0.000794956271094592 GO:0033218 amide binding 5/35 247/18639 0.0202429149797571 10.7802197802198 9.2065784264858e-05 0.00699699960412921 GO:0048407 platelet-derived growth factor binding 2/35 11/18639 0.181818181818182 96.825974025974 0.000186411646466523 0.00929558754830693 GO:0038024 cargo receptor activity 3/35 65/18639 0.0461538461538462 24.5789010989011 0.000244620724955445 0.00929558754830693 GO:0001540 amyloid-beta binding 3/35 83/18639 0.036144578313253 19.2485370051635 0.00050279861059129 0.0130289080311984 GO:0035615 clathrin adaptor activity 2/35 18/18639 0.111111111111111 59.1714285714286 0.000514299001231518 0.0130289080311984 GO:0140312 cargo adaptor activity 2/35 21/18639 0.0952380952380952 50.7183673469388 0.000703408282402094 0.015274008417874 GO:0002020 protease binding 3/35 136/18639 0.0220588235294118 11.747268907563 0.00209640343492832 0.039831665263638 GO:0019955 cytokine binding 3/35 144/18639 0.0208333333333333 11.0946428571429 0.00246623795425888 0.0416520187830389 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/35 44/18639 0.0454545454545455 24.2064935064935 0.00308403665048349 0.0468773570873491 GO:0016829 lyase activity 3/35 200/18639 0.015 7.98814285714286 0.00618729577225294 0.0854971779438588 GO:0004518 nuclease activity 3/35 209/18639 0.0143540669856459 7.64415584415584 0.0069846288997795 0.0884719660638736 GO:0004521 RNA endonuclease activity 2/35 73/18639 0.0273972602739726 14.5902152641879 0.00828073332337704 0.09682088193487 GO:0046332 SMAD binding 2/35 79/18639 0.0253164556962025 13.4820976491863 0.00964011411165867 0.104664096069437 GO:0042277 peptide binding 3/35 249/18639 0.0120481927710843 6.41617900172117 0.0112503323149085 0.11400336745774 GO:0005381 iron ion transmembrane transporter activity 1/35 10/18639 0.1 53.2542857142857 0.0186244092187168 0.141159585022732 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/35 10/18639 0.1 53.2542857142857 0.0186244092187168 0.141159585022732 GO:0043121 neurotrophin binding 1/35 10/18639 0.1 53.2542857142857 0.0186244092187168 0.141159585022732 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/35 10/18639 0.1 53.2542857142857 0.0186244092187168 0.141159585022732 GO:0034713 type I transforming growth factor beta receptor binding 1/35 11/18639 0.0909090909090909 48.412987012987 0.0204682089759419 0.141159585022732 GO:0004540 RNA nuclease activity 2/35 121/18639 0.0165289256198347 8.80236127508855 0.0216279180102343 0.141159585022732 GO:0034452 dynactin binding 1/35 12/18639 0.0833333333333333 44.3785714285714 0.0223086434125875 0.141159585022732 GO:0004519 endonuclease activity 2/35 127/18639 0.015748031496063 8.38650168728909 0.0236693402479652 0.141159585022732 GO:0005542 folic acid binding 1/35 13/18639 0.0769230769230769 40.9648351648352 0.0241457184907304 0.141159585022732 GO:0017154 semaphorin receptor activity 1/35 13/18639 0.0769230769230769 40.9648351648352 0.0241457184907304 0.141159585022732 GO:0035673 oligopeptide transmembrane transporter activity 1/35 13/18639 0.0769230769230769 40.9648351648352 0.0241457184907304 0.141159585022732 GO:0008559 ABC-type xenobiotic transporter activity 1/35 14/18639 0.0714285714285714 38.0387755102041 0.0259794401622014 0.143222544109363 GO:0015929 hexosaminidase activity 1/35 15/18639 0.0666666666666667 35.5028571428571 0.0278098143686079 0.143222544109363 GO:0016846 carbon-sulfur lyase activity 1/35 15/18639 0.0666666666666667 35.5028571428571 0.0278098143686079 0.143222544109363 GO:0005159 insulin-like growth factor receptor binding 1/35 16/18639 0.0625 33.2839285714286 0.0296368470413477 0.143222544109363 GO:0015562 efflux transmembrane transporter activity 1/35 16/18639 0.0625 33.2839285714286 0.0296368470413477 0.143222544109363 GO:0030169 low-density lipoprotein particle binding 1/35 17/18639 0.0588235294117647 31.3260504201681 0.0314605441016252 0.143222544109363 GO:0008409 5'-3' exonuclease activity 1/35 18/18639 0.0555555555555556 29.5857142857143 0.0332809114604721 0.143222544109363 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/35 18/18639 0.0555555555555556 29.5857142857143 0.0332809114604721 0.143222544109363 GO:0005178 integrin binding 2/35 161/18639 0.0124223602484472 6.61543921916593 0.03662628323487 0.143222544109363 GO:0015399 primary active transmembrane transporter activity 2/35 166/18639 0.0120481927710843 6.41617900172117 0.0387186848227925 0.143222544109363 GO:0005201 extracellular matrix structural constituent 2/35 168/18639 0.0119047619047619 6.33979591836735 0.0395682978478062 0.143222544109363 GO:0061133 endopeptidase activator activity 1/35 22/18639 0.0454545454545455 24.2064935064935 0.0405292017469829 0.143222544109363 GO:0008201 heparin binding 2/35 172/18639 0.0116279069767442 6.19235880398671 0.0412888699533532 0.143222544109363 GO:0004602 glutathione peroxidase activity 1/35 23/18639 0.0434782608695652 23.1540372670807 0.0423330089091923 0.143222544109363 GO:0005158 insulin receptor binding 1/35 23/18639 0.0434782608695652 23.1540372670807 0.0423330089091923 0.143222544109363 GO:0016849 phosphorus-oxygen lyase activity 1/35 23/18639 0.0434782608695652 23.1540372670807 0.0423330089091923 0.143222544109363 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/35 25/18639 0.04 21.3017142857143 0.0459307457299629 0.143222544109363 GO:0061135 endopeptidase regulator activity 2/35 184/18639 0.0108695652173913 5.78850931677019 0.0466169253877223 0.143222544109363 GO:0004529 DNA exonuclease activity 1/35 26/18639 0.0384615384615385 20.4824175824176 0.0477246870590405 0.143222544109363 GO:0005160 transforming growth factor beta receptor binding 1/35 26/18639 0.0384615384615385 20.4824175824176 0.0477246870590405 0.143222544109363 GO:0015216 purine nucleotide transmembrane transporter activity 1/35 26/18639 0.0384615384615385 20.4824175824176 0.0477246870590405 0.143222544109363 GO:0030507 spectrin binding 1/35 26/18639 0.0384615384615385 20.4824175824176 0.0477246870590405 0.143222544109363 GO:0050750 low-density lipoprotein particle receptor binding 1/35 26/18639 0.0384615384615385 20.4824175824176 0.0477246870590405 0.143222544109363 GO:0004364 glutathione transferase activity 1/35 27/18639 0.037037037037037 19.7238095238095 0.0495153514308738 0.143222544109363 GO:0005044 scavenger receptor activity 1/35 27/18639 0.037037037037037 19.7238095238095 0.0495153514308738 0.143222544109363 GO:0003779 actin binding 3/35 443/18639 0.00677200902934537 3.60638503708481 0.0498167904850454 0.143222544109363 GO:0097718 disordered domain specific binding 1/35 28/18639 0.0357142857142857 19.019387755102 0.0513027446556713 0.143222544109363 GO:0003785 actin monomer binding 1/35 29/18639 0.0344827586206897 18.3635467980296 0.053086872533649 0.143222544109363 GO:0015215 nucleotide transmembrane transporter activity 1/35 30/18639 0.0333333333333333 17.7514285714286 0.0548677408550529 0.143222544109363 GO:0017147 Wnt-protein binding 1/35 31/18639 0.032258064516129 17.178801843318 0.0566453554001696 0.143222544109363 GO:0070325 lipoprotein particle receptor binding 1/35 31/18639 0.032258064516129 17.178801843318 0.0566453554001696 0.143222544109363 GO:0072349 modified amino acid transmembrane transporter activity 1/35 31/18639 0.032258064516129 17.178801843318 0.0566453554001696 0.143222544109363 GO:0022884 macromolecule transmembrane transporter activity 1/35 32/18639 0.03125 16.6419642857143 0.0584197219393453 0.143222544109363 GO:0042910 xenobiotic transmembrane transporter activity 1/35 32/18639 0.03125 16.6419642857143 0.0584197219393453 0.143222544109363 GO:0071813 lipoprotein particle binding 1/35 32/18639 0.03125 16.6419642857143 0.0584197219393453 0.143222544109363 GO:0071814 protein-lipid complex binding 1/35 32/18639 0.03125 16.6419642857143 0.0584197219393453 0.143222544109363 GO:0019956 chemokine binding 1/35 33/18639 0.0303030303030303 16.1376623376623 0.0601908462330051 0.145222359165346 GO:0061134 peptidase regulator activity 2/35 226/18639 0.00884955752212389 4.71276864728192 0.0670682272920037 0.157245252981681 GO:0043394 proteoglycan binding 1/35 37/18639 0.027027027027027 14.3930501930502 0.0672430358145346 0.157245252981681 GO:0042887 amide transmembrane transporter activity 1/35 38/18639 0.0263157894736842 14.0142857142857 0.0689980349407838 0.158904565318169 GO:0001530 lipopolysaccharide binding 1/35 41/18639 0.024390243902439 12.988850174216 0.074243807732704 0.161838410086572 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/35 41/18639 0.024390243902439 12.988850174216 0.074243807732704 0.161838410086572 GO:0005539 glycosaminoglycan binding 2/35 242/18639 0.00826446280991736 4.40118063754427 0.0755211008790739 0.161838410086572 GO:0035198 miRNA binding 1/35 42/18639 0.0238095238095238 12.6795918367347 0.0759860094065048 0.161838410086572 GO:0042056 chemoattractant activity 1/35 42/18639 0.0238095238095238 12.6795918367347 0.0759860094065048 0.161838410086572 GO:0008375 acetylglucosaminyltransferase activity 1/35 43/18639 0.0232558139534884 12.3847176079734 0.0777250258968405 0.161838410086572 GO:0048156 tau protein binding 1/35 43/18639 0.0232558139534884 12.3847176079734 0.0777250258968405 0.161838410086572 GO:0003954 NADH dehydrogenase activity 1/35 44/18639 0.0227272727272727 12.1032467532468 0.0794608628560581 0.163216907488119 GO:0046915 transition metal ion transmembrane transporter activity 1/35 45/18639 0.0222222222222222 11.8342857142857 0.0811935259267781 0.164552212544937 GO:0140359 ABC-type transporter activity 1/35 47/18639 0.0212765957446809 11.3306990881459 0.084649352924669 0.169298705849338 GO:0015605 organophosphate ester transmembrane transporter activity 1/35 50/18639 0.02 10.6508571428571 0.0898094297657741 0.175988648200505 GO:0005021 vascular endothelial growth factor receptor activity 1/35 51/18639 0.0196078431372549 10.4420168067227 0.0915231674578605 0.175988648200505 GO:0005080 protein kinase C binding 1/35 52/18639 0.0192307692307692 10.2412087912088 0.0932337704887936 0.175988648200505 GO:1901681 sulfur compound binding 2/35 275/18639 0.00727272727272727 3.87303896103896 0.0939486395224388 0.175988648200505 GO:0017046 peptide hormone binding 1/35 53/18639 0.0188679245283019 10.0479784366577 0.0949412444239569 0.175988648200505 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/35 53/18639 0.0188679245283019 10.0479784366577 0.0949412444239569 0.175988648200505 GO:0140463 chromatin-protein adaptor activity 1/35 54/18639 0.0185185185185185 9.86190476190476 0.0966455948191559 0.17698952304231 GO:0004601 peroxidase activity 1/35 57/18639 0.0175438596491228 9.34285714285714 0.101739960179597 0.17731544170611 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/35 57/18639 0.0175438596491228 9.34285714285714 0.101739960179597 0.17731544170611 GO:0016504 peptidase activator activity 1/35 57/18639 0.0175438596491228 9.34285714285714 0.101739960179597 0.17731544170611 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/35 58/18639 0.0172413793103448 9.18177339901478 0.103431871781885 0.17731544170611 GO:0061980 regulatory RNA binding 1/35 58/18639 0.0172413793103448 9.18177339901478 0.103431871781885 0.17731544170611 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/35 59/18639 0.0169491525423729 9.02615012106538 0.105120687480052 0.17731544170611 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/35 60/18639 0.0166666666666667 8.87571428571428 0.106806412772743 0.17731544170611 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/35 60/18639 0.0166666666666667 8.87571428571428 0.106806412772743 0.17731544170611 GO:0015026 coreceptor activity 1/35 61/18639 0.0163934426229508 8.73021077283372 0.108489053149133 0.17731544170611 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/35 61/18639 0.0163934426229508 8.73021077283372 0.108489053149133 0.17731544170611 GO:1901682 sulfur compound transmembrane transporter activity 1/35 63/18639 0.0158730158730159 8.4530612244898 0.111845101062452 0.180855908100986 GO:0004536 DNA nuclease activity 1/35 64/18639 0.015625 8.32098214285714 0.113518519530519 0.18162963124883 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/35 68/18639 0.0147058823529412 7.83151260504202 0.120181617236573 0.190287560624573 GO:0098631 cell adhesion mediator activity 1/35 76/18639 0.0131578947368421 7.00714285714286 0.133362172680479 0.20897989945807 GO:0019199 transmembrane receptor protein kinase activity 1/35 78/18639 0.0128205128205128 6.82747252747253 0.136627220798765 0.211911607769513 GO:0048306 calcium-dependent protein binding 1/35 80/18639 0.0125 6.65678571428571 0.139880318056859 0.214765740854976 GO:0004527 exonuclease activity 1/35 84/18639 0.0119047619047619 6.33979591836735 0.146350829690291 0.222453261129242 GO:0016209 antioxidant activity 1/35 86/18639 0.0116279069767442 6.19235880398671 0.149568328549258 0.223285143446853 GO:0008081 phosphoric diester hydrolase activity 1/35 87/18639 0.0114942528735632 6.12118226600985 0.151172657148448 0.223285143446853 GO:0004197 cysteine-type endopeptidase activity 1/35 88/18639 0.0113636363636364 6.05162337662338 0.152774045516268 0.223285143446853 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/35 88/18639 0.0113636363636364 6.05162337662338 0.152774045516268 0.223285143446853 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/35 91/18639 0.010989010989011 5.85211930926217 0.157560621489595 0.22593598553225 GO:0072341 modified amino acid binding 1/35 91/18639 0.010989010989011 5.85211930926217 0.157560621489595 0.22593598553225 GO:0042562 hormone binding 1/35 94/18639 0.0106382978723404 5.66534954407295 0.162320923131509 0.228663175829698 GO:0004867 serine-type endopeptidase inhibitor activity 1/35 95/18639 0.0105263157894737 5.60571428571428 0.16390187582444 0.228663175829698 GO:0140098 catalytic activity, acting on RNA 2/35 387/18639 0.00516795865633075 2.75215946843854 0.164009566352884 0.228663175829698 GO:0004896 cytokine receptor activity 1/35 96/18639 0.0104166666666667 5.54732142857143 0.165479929876755 0.228663175829698 GO:0042626 ATPase-coupled transmembrane transporter activity 1/35 98/18639 0.0102040816326531 5.43411078717201 0.168627362684872 0.230913145298203 GO:0004620 phospholipase activity 1/35 109/18639 0.00917431192660551 4.88571428571429 0.185733191297188 0.252066473903326 GO:0009055 electron transfer activity 1/35 116/18639 0.00862068965517241 4.59088669950739 0.196440175840184 0.264238112634584 GO:0022853 active monoatomic ion transmembrane transporter activity 1/35 118/18639 0.00847457627118644 4.51307506053269 0.199474109902851 0.265965479870467 GO:0022804 active transmembrane transporter activity 2/35 457/18639 0.00437636761487965 2.33060331353548 0.211520167421015 0.279574482156472 GO:0016298 lipase activity 1/35 130/18639 0.00769230769230769 4.09648351648352 0.217445389745001 0.282493155908035 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/35 130/18639 0.00769230769230769 4.09648351648352 0.217445389745001 0.282493155908035 GO:0005179 hormone activity 1/35 132/18639 0.00757575757575758 4.03441558441558 0.220402248958322 0.283907981709025 GO:0004713 protein tyrosine kinase activity 1/35 140/18639 0.00714285714285714 3.80387755102041 0.232121528273035 0.296491363844549 GO:0005543 phospholipid binding 2/35 497/18639 0.00402414486921529 2.14302960620868 0.23931702746819 0.300682355554539 GO:0008194 UDP-glycosyltransferase activity 1/35 145/18639 0.00689655172413793 3.67270935960591 0.239358980408547 0.300682355554539 GO:0019842 vitamin binding 1/35 150/18639 0.00666666666666667 3.55028571428571 0.246530148827893 0.307152316572457 GO:0140375 immune receptor activity 1/35 156/18639 0.00641025641025641 3.41373626373626 0.255048885885287 0.315182363045233 GO:0004866 endopeptidase inhibitor activity 1/35 161/18639 0.0062111801242236 3.30771960958296 0.262076297519995 0.320384422376669 GO:0008083 growth factor activity 1/35 162/18639 0.00617283950617284 3.28730158730159 0.26347403155976 0.320384422376669 GO:0015103 inorganic anion transmembrane transporter activity 1/35 165/18639 0.00606060606060606 3.22753246753247 0.267651820009744 0.322881560646675 GO:0030414 peptidase inhibitor activity 1/35 169/18639 0.00591715976331361 3.15114116652578 0.273186410366412 0.326963262800745 GO:0015078 proton transmembrane transporter activity 1/35 185/18639 0.00540540540540541 2.87861003861004 0.294921254773427 0.34795525070058 GO:0008234 cysteine-type peptidase activity 1/35 187/18639 0.0053475935828877 2.84782276546982 0.297593306520233 0.34795525070058 GO:0031406 carboxylic acid binding 1/35 187/18639 0.0053475935828877 2.84782276546982 0.297593306520233 0.34795525070058 GO:0043177 organic acid binding 1/35 189/18639 0.00529100529100529 2.81768707482993 0.300255520194578 0.348388084500579 GO:0016758 hexosyltransferase activity 1/35 197/18639 0.0050761421319797 2.7032632342277 0.310806695555339 0.35789861912433 GO:0005516 calmodulin binding 1/35 207/18639 0.00483091787439614 2.57267080745342 0.323778491486944 0.370032561699365 GO:0051015 actin filament binding 1/35 209/18639 0.00478468899521531 2.54805194805195 0.32634423830026 0.370181524042086 GO:0016757 glycosyltransferase activity 1/35 267/18639 0.00374531835205993 1.99454253611557 0.396770929080859 0.445298938911262 GO:0008514 organic anion transmembrane transporter activity 1/35 269/18639 0.00371747211895911 1.97971322357939 0.39906719297127 0.445298938911262 GO:0005096 GTPase activator activity 1/35 271/18639 0.003690036900369 1.96510279388508 0.401354964676598 0.445298938911262 GO:0005126 cytokine receptor binding 1/35 275/18639 0.00363636363636364 1.93651948051948 0.405905153369569 0.447083937044743 GO:0030246 carbohydrate binding 1/35 280/18639 0.00357142857142857 1.9019387755102 0.411545661478189 0.450035543486941 GO:0035091 phosphatidylinositol binding 1/35 284/18639 0.00352112676056338 1.8751509054326 0.416020579135813 0.451679485918883 GO:0140097 catalytic activity, acting on DNA 1/35 336/18639 0.00297619047619048 1.58494897959184 0.47127033672078 0.508036107670628 GO:0042578 phosphoric ester hydrolase activity 1/35 363/18639 0.00275482093663912 1.46706021251476 0.497919642606187 0.532984406170003 GO:0046982 protein heterodimerization activity 1/35 369/18639 0.002710027100271 1.44320557491289 0.503662017864674 0.535361025982031 GO:0004175 endopeptidase activity 1/35 405/18639 0.00246913580246914 1.31492063492063 0.536799883417687 0.566622099163114 GO:0004857 enzyme inhibitor activity 1/35 416/18639 0.00240384615384615 1.2801510989011 0.54648938203711 0.569854680798023 GO:0016887 ATP hydrolysis activity 1/35 417/18639 0.00239808153477218 1.27708119218911 0.547360417082311 0.569854680798023 GO:0046873 metal ion transmembrane transporter activity 1/35 450/18639 0.00222222222222222 1.18342857142857 0.575210188262398 0.594775160652276 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 1/35 484/18639 0.00206611570247934 1.10029515938607 0.602160855049346 0.611270282211514 GO:0030695 GTPase regulator activity 1/35 489/18639 0.00204498977505112 1.08904469763365 0.605981374977923 0.611270282211514 GO:0060589 nucleoside-triphosphatase regulator activity 1/35 490/18639 0.00204081632653061 1.0868221574344 0.606741190508269 0.611270282211514 GO:0001216 DNA-binding transcription activator activity 1/35 491/18639 0.00203665987780041 1.08460867035205 0.607499582614292 0.611270282211514 GO:0016755 aminoacyltransferase activity 1/35 496/18639 0.00201612903225806 1.07367511520737 0.611270282211514 0.611270282211514