ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 95/982 175/18639 0.542857142857143 10.3037823683445 1.31072146592969e-74 1.36839321043059e-71 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 35/982 68/18639 0.514705882352941 9.76945309692105 5.25653967498443e-27 2.74391371034187e-24 GO:0009055 electron transfer activity 40/982 116/18639 0.344827586206897 6.54505232108996 1.60596767170136e-22 5.58876749752073e-20 GO:0022853 active monoatomic ion transmembrane transporter activity 40/982 118/18639 0.338983050847458 6.434119230902 3.33534202390919e-22 8.70524268240298e-20 GO:0008137 NADH dehydrogenase (ubiquinone) activity 22/982 41/18639 0.536585365853659 10.1847399533058 5.63641095504722e-18 1.17688260741386e-15 GO:0003954 NADH dehydrogenase activity 22/982 44/18639 0.5 9.49032586558045 4.16550732500617e-17 6.54902673770143e-15 GO:0015399 primary active transmembrane transporter activity 41/982 166/18639 0.246987951807229 4.68799229504576 4.39110988160058e-17 6.54902673770143e-15 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 24/982 58/18639 0.413793103448276 7.85406278530796 3.66869043347356e-16 4.787641015683e-14 GO:0015078 proton transmembrane transporter activity 41/982 185/18639 0.221621621621622 4.20652281609512 2.59901435732599e-15 3.01485665449814e-13 GO:0016651 oxidoreductase activity, acting on NAD(P)H 25/982 88/18639 0.284090909090909 5.39223060544344 2.04215147847021e-12 2.1320061435229e-10 GO:0019843 rRNA binding 19/982 65/18639 0.292307692307692 5.54819050603165 5.32349770495513e-10 5.05248327633923e-08 GO:0016675 oxidoreductase activity, acting on a heme group of donors 10/982 16/18639 0.625 11.8629073319756 9.44034260454709e-10 8.21309806595597e-08 GO:0022804 active transmembrane transporter activity 56/982 457/18639 0.12253829321663 2.32585666727573 3.42166907112648e-09 2.74786346942772e-07 GO:0004129 cytochrome-c oxidase activity 9/982 15/18639 0.6 11.3883910386965 1.13283304933002e-08 8.44769788214674e-07 GO:0004601 peroxidase activity 14/982 57/18639 0.245614035087719 4.66191446028513 1.06383797081485e-06 7.40431227687132e-05 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 14/982 59/18639 0.23728813559322 4.5038834616314 1.66610437791294e-06 0.000108713310658819 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/982 15/18639 0.466666666666667 8.85763747454175 4.88804146930632e-06 0.000300183252585635 GO:1990948 ubiquitin ligase inhibitor activity 6/982 11/18639 0.545454545454545 10.3530827624514 7.74321097596084e-06 0.000449106236605729 GO:0005201 extracellular matrix structural constituent 24/982 168/18639 0.142857142857143 2.71152167588013 8.17462826443653e-06 0.000449174310951144 GO:0016209 antioxidant activity 16/982 86/18639 0.186046511627907 3.53128404300668 9.29616878720259e-06 0.000485260010691975 GO:0005178 integrin binding 23/982 161/18639 0.142857142857143 2.71152167588013 1.25347795427416e-05 0.000623157611553439 GO:0045296 cadherin binding 37/982 334/18639 0.110778443113772 2.10264704806273 1.63709791925527e-05 0.000776877376228412 GO:0048027 mRNA 5'-UTR binding 8/982 24/18639 0.333333333333333 6.32688391038697 1.99136146275902e-05 0.000903904942226267 GO:0050840 extracellular matrix binding 13/982 67/18639 0.194029850746269 3.68281302246405 3.97998387913835e-05 0.00173129298742518 GO:0004857 enzyme inhibitor activity 42/982 416/18639 0.100961538461538 1.91631579978067 4.22682677610797e-05 0.00176512286170269 GO:0043021 ribonucleoprotein complex binding 23/982 177/18639 0.129943502824859 2.46641237184577 5.81300269772455e-05 0.00233414416016324 GO:0031386 protein tag activity 6/982 15/18639 0.4 7.59226069246436 6.98862600949514e-05 0.00260575912639747 GO:0141047 molecular tag activity 6/982 15/18639 0.4 7.59226069246436 6.98862600949514e-05 0.00260575912639747 GO:0055106 ubiquitin-protein transferase regulator activity 9/982 36/18639 0.25 4.74516293279022 7.81515182631152e-05 0.00281345465747215 GO:0019838 growth factor binding 19/982 136/18639 0.139705882352941 2.65170869773571 9.45661494897093e-05 0.00329090200224188 GO:0003779 actin binding 42/982 443/18639 0.0948081264108352 1.79952002868794 0.000172829594062926 0.00582045471618371 GO:0016860 intramolecular oxidoreductase activity 10/982 53/18639 0.188679245283019 3.58125504361526 0.00038769524660854 0.0126485574206036 GO:0005539 glycosaminoglycan binding 26/982 242/18639 0.107438016528926 2.03924357442225 0.000457678413933053 0.0144792807317002 GO:0098631 cell adhesion mediator activity 12/982 76/18639 0.157894736842105 2.9969450101833 0.000586139990546068 0.0179979455920616 GO:0016504 peptidase activator activity 10/982 57/18639 0.175438596491228 3.32993890020367 0.000709672411517183 0.0211685142178268 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 5/982 15/18639 0.333333333333333 6.32688391038697 0.000774341876659163 0.0221381993190167 GO:0043022 ribosome binding 15/982 112/18639 0.133928571428571 2.54205157113762 0.000784591355175878 0.0221381993190167 GO:0004602 glutathione peroxidase activity 6/982 23/18639 0.260869565217391 4.95147436465067 0.000980605533735769 0.0269408467689511 GO:0005159 insulin-like growth factor receptor binding 5/982 16/18639 0.3125 5.93145366598778 0.00107775116929986 0.0288505697627961 GO:0001094 TFIID-class transcription factor complex binding 4/982 10/18639 0.4 7.59226069246436 0.00124510402974344 0.0309942384408071 GO:0070513 death domain binding 4/982 10/18639 0.4 7.59226069246436 0.00124510402974344 0.0309942384408071 GO:0050431 transforming growth factor beta binding 6/982 24/18639 0.25 4.74516293279022 0.00124977505526339 0.0309942384408071 GO:0005518 collagen binding 11/982 72/18639 0.152777777777778 2.89982179226069 0.00129665123332325 0.0309942384408071 GO:0001540 amyloid-beta binding 12/982 83/18639 0.144578313253012 2.74419061173411 0.00130627058562789 0.0309942384408071 GO:0033218 amide binding 25/982 247/18639 0.101214574898785 1.92111859627135 0.00137658778184642 0.0319368365388369 GO:0051015 actin filament binding 22/982 209/18639 0.105263157894737 1.9979633401222 0.0015796050981081 0.0358501678788013 GO:0010854 adenylate cyclase regulator activity 4/982 11/18639 0.363636363636364 6.9020551749676 0.00187534322811897 0.0399904612093398 GO:0070990 snRNP binding 4/982 11/18639 0.363636363636364 6.9020551749676 0.00187534322811897 0.0399904612093398 GO:0003746 translation elongation factor activity 5/982 18/18639 0.277777777777778 5.2724032586558 0.00193604249141338 0.0399904612093398 GO:0061134 peptidase regulator activity 23/982 226/18639 0.101769911504425 1.93165924697655 0.0019533420030187 0.0399904612093398 GO:0050750 low-density lipoprotein particle receptor binding 6/982 26/18639 0.230769230769231 4.38015039949867 0.00195355701309993 0.0399904612093398 GO:0002020 protease binding 16/982 136/18639 0.117647058823529 2.23301785072481 0.00215282567352436 0.0432221154453738 GO:0005520 insulin-like growth factor binding 5/982 19/18639 0.263157894736842 4.9949083503055 0.00251467612538648 0.049534374998179 GO:0016835 carbon-oxygen lyase activity 11/982 79/18639 0.139240506329114 2.64287555750342 0.00277636447888763 0.0536763799251608 GO:0042277 peptide binding 24/982 249/18639 0.0963855421686747 1.82946040782274 0.00322952935613831 0.0613023390510617 GO:0043236 laminin binding 6/982 29/18639 0.206896551724138 3.92703139265398 0.0035224363127773 0.0656682769739196 GO:0031994 insulin-like growth factor I binding 4/982 13/18639 0.307692307692308 5.84020053266489 0.00373372088832259 0.0683860457440138 GO:0008201 heparin binding 18/982 172/18639 0.104651162790698 1.98634727419126 0.004287207173569 0.077169729124242 GO:0015036 disulfide oxidoreductase activity 7/982 40/18639 0.175 3.32161405295316 0.00447140805867357 0.0791211866653425 GO:0070325 lipoprotein particle receptor binding 6/982 31/18639 0.193548387096774 3.67367452861179 0.00499193445516694 0.0843855081371801 GO:0032036 myosin heavy chain binding 4/982 14/18639 0.285714285714286 5.42304335176026 0.00501139990852985 0.0843855081371801 GO:0044548 S100 protein binding 4/982 14/18639 0.285714285714286 5.42304335176026 0.00501139990852985 0.0843855081371801 GO:1901681 sulfur compound binding 25/982 275/18639 0.0909090909090909 1.7255137937419 0.00572198005280194 0.0948213837321465 GO:0008307 structural constituent of muscle 7/982 42/18639 0.166666666666667 3.16344195519348 0.00590712050971097 0.0963599033146601 GO:0004864 protein phosphatase inhibitor activity 8/982 53/18639 0.150943396226415 2.86500403489221 0.00620497931664526 0.0996615139473486 GO:0016853 isomerase activity 18/982 180/18639 0.1 1.89806517311609 0.00685641014643603 0.106795121160673 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 8/982 54/18639 0.148148148148148 2.81194840461643 0.0069560040602737 0.106795121160673 GO:0017069 snRNA binding 8/982 54/18639 0.148148148148148 2.81194840461643 0.0069560040602737 0.106795121160673 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/982 24/18639 0.208333333333333 3.95430244399185 0.00738828437840158 0.111787954942772 GO:0016247 channel regulator activity 17/982 168/18639 0.101190476190476 1.92066118708176 0.00753388973855286 0.112362584100703 GO:0030547 signaling receptor inhibitor activity 7/982 44/18639 0.159090909090909 3.01964913904832 0.00766158092974739 0.112657612544455 GO:0015035 protein-disulfide reductase activity 6/982 34/18639 0.176470588235294 3.34952677608722 0.00797509300084161 0.115638848512203 GO:0017070 U6 snRNA binding 4/982 16/18639 0.25 4.74516293279022 0.00837694732190745 0.119133699362839 GO:0141108 transporter regulator activity 17/982 170/18639 0.1 1.89806517311609 0.00844434267514376 0.119133699362839 GO:0019212 phosphatase inhibitor activity 8/982 56/18639 0.142857142857143 2.71152167588013 0.00866145794327017 0.120567494570321 GO:0031625 ubiquitin protein ligase binding 26/982 302/18639 0.0860927152317881 1.63409584440458 0.00972119143506758 0.13353847181856 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 6/982 36/18639 0.166666666666667 3.16344195519348 0.0105662551293722 0.139635067785628 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 6/982 36/18639 0.166666666666667 3.16344195519348 0.0105662551293722 0.139635067785628 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 6/982 36/18639 0.166666666666667 3.16344195519348 0.0105662551293722 0.139635067785628 GO:0003714 transcription corepressor activity 19/982 204/18639 0.0931372549019608 1.76780579849048 0.0115849585285443 0.151001054417272 GO:0008135 translation factor activity, RNA binding 10/982 83/18639 0.120481927710843 2.28682550977842 0.0117155990496159 0.151001054417272 GO:0044325 transmembrane transporter binding 14/982 136/18639 0.102941176470588 1.95389061938421 0.0125628622824783 0.159629382589682 GO:0180051 translation factor activity 10/982 84/18639 0.119047619047619 2.25960139656677 0.0126908417192946 0.159629382589682 GO:0005528 FK506 binding 3/982 10/18639 0.3 5.69419551934827 0.0132376740262069 0.164525377182857 GO:0005501 retinoid binding 6/982 38/18639 0.157894736842105 2.9969450101833 0.0137033831819839 0.166352698162688 GO:0019840 isoprenoid binding 6/982 38/18639 0.157894736842105 2.9969450101833 0.0137033831819839 0.166352698162688 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 6/982 39/18639 0.153846153846154 2.92010026633245 0.015492898556672 0.185914782680064 GO:0016918 retinal binding 4/982 19/18639 0.210526315789474 3.9959266802444 0.0157367504866383 0.186695085318754 GO:0004629 phospholipase C activity 5/982 29/18639 0.172413793103448 3.27252616054498 0.0166203940329757 0.194962824386816 GO:0005048 signal sequence binding 7/982 51/18639 0.137254901960784 2.60518749251228 0.0168653068599124 0.195637559574984 GO:0015217 ADP transmembrane transporter activity 3/982 11/18639 0.272727272727273 5.1765413812257 0.0174985480754899 0.198570480334907 GO:0048407 platelet-derived growth factor binding 3/982 11/18639 0.272727272727273 5.1765413812257 0.0174985480754899 0.198570480334907 GO:0003727 single-stranded RNA binding 10/982 89/18639 0.112359550561798 2.13265749788325 0.0185063123868944 0.205597616533798 GO:0010851 cyclase regulator activity 4/982 20/18639 0.2 3.79613034623218 0.0188686494646351 0.205597616533798 GO:0016505 peptidase activator activity involved in apoptotic process 4/982 20/18639 0.2 3.79613034623218 0.0188686494646351 0.205597616533798 GO:0001968 fibronectin binding 5/982 30/18639 0.166666666666667 3.16344195519348 0.0191024605400177 0.205597616533798 GO:0031210 phosphatidylcholine binding 5/982 30/18639 0.166666666666667 3.16344195519348 0.0191024605400177 0.205597616533798 GO:0051540 metal cluster binding 9/982 77/18639 0.116883116883117 2.21851773481101 0.0196109570596878 0.208916726227695 GO:0044389 ubiquitin-like protein ligase binding 26/982 322/18639 0.0807453416149068 1.53259920810616 0.0205640453199016 0.216857205191689 GO:0016859 cis-trans isomerase activity 6/982 42/18639 0.142857142857143 2.71152167588013 0.021816865081622 0.227374979644731 GO:0005527 macrolide binding 3/982 12/18639 0.25 4.74516293279022 0.022432588987938 0.227374979644731 GO:0010853 cyclase activator activity 3/982 12/18639 0.25 4.74516293279022 0.022432588987938 0.227374979644731 GO:0097371 MDM2/MDM4 family protein binding 3/982 12/18639 0.25 4.74516293279022 0.022432588987938 0.227374979644731 GO:0051087 protein-folding chaperone binding 13/982 134/18639 0.0970149253731343 1.84140651123203 0.0245862369327744 0.245543927648821 GO:0098632 cell-cell adhesion mediator activity 7/982 55/18639 0.127272727272727 2.41571931123866 0.0246955099646802 0.245543927648821 GO:0051082 unfolded protein binding 12/982 121/18639 0.0991735537190083 1.88237868408207 0.0258364340719639 0.25112161558869 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/982 22/18639 0.181818181818182 3.4510275874838 0.0262186361103134 0.25112161558869 GO:0031683 G-protein beta/gamma-subunit complex binding 4/982 22/18639 0.181818181818182 3.4510275874838 0.0262186361103134 0.25112161558869 GO:0061133 endopeptidase activator activity 4/982 22/18639 0.181818181818182 3.4510275874838 0.0262186361103134 0.25112161558869 GO:0016248 channel inhibitor activity 6/982 44/18639 0.136363636363636 2.58827069061285 0.0268824511010372 0.255138899540753 GO:0017154 semaphorin receptor activity 3/982 13/18639 0.230769230769231 4.38015039949867 0.0280422494178226 0.261393824930418 GO:0045159 myosin II binding 3/982 13/18639 0.230769230769231 4.38015039949867 0.0280422494178226 0.261393824930418 GO:0141110 transporter inhibitor activity 6/982 45/18639 0.133333333333333 2.53075356415479 0.0296843003288938 0.274251411888187 GO:0017134 fibroblast growth factor binding 4/982 23/18639 0.173913043478261 3.30098290976711 0.0304521535505027 0.278877616725656 GO:0061135 endopeptidase regulator activity 16/982 184/18639 0.0869565217391304 1.65049145488356 0.0340275611124953 0.308910511737759 GO:0005347 ATP transmembrane transporter activity 3/982 14/18639 0.214285714285714 4.06728251382019 0.0343233901930843 0.308910511737759 GO:0005504 fatty acid binding 6/982 47/18639 0.127659574468085 2.42306192312692 0.0358458824768121 0.319855566716169 GO:0008081 phosphoric diester hydrolase activity 9/982 87/18639 0.103448275862069 1.96351569632699 0.0393812328558921 0.348423788996198 GO:0016836 hydro-lyase activity 7/982 61/18639 0.114754098360656 2.17810757570699 0.0406027943565253 0.356048871900122 GO:0050700 CARD domain binding 3/982 15/18639 0.2 3.79613034623218 0.0412662006704164 0.356048871900122 GO:0051371 muscle alpha-actinin binding 3/982 15/18639 0.2 3.79613034623218 0.0412662006704164 0.356048871900122 GO:0004197 cysteine-type endopeptidase activity 9/982 88/18639 0.102272727272727 1.94120301795964 0.0419069544429458 0.35861361015111 GO:0022829 wide pore channel activity 5/982 37/18639 0.135135135135135 2.56495293664336 0.0432908310888667 0.361565021254215 GO:0042805 actinin binding 5/982 37/18639 0.135135135135135 2.56495293664336 0.0432908310888667 0.361565021254215 GO:0043394 proteoglycan binding 5/982 37/18639 0.135135135135135 2.56495293664336 0.0432908310888667 0.361565021254215 GO:0019208 phosphatase regulator activity 11/982 117/18639 0.094017094017094 1.78450571831427 0.0445434997818013 0.367725631929098 GO:0004435 phosphatidylinositol phospholipase C activity 4/982 26/18639 0.153846153846154 2.92010026633245 0.0454373625659518 0.367725631929098 GO:0005112 Notch binding 4/982 26/18639 0.153846153846154 2.92010026633245 0.0454373625659518 0.367725631929098 GO:0008143 poly(A) binding 4/982 26/18639 0.153846153846154 2.92010026633245 0.0454373625659518 0.367725631929098 GO:0051536 iron-sulfur cluster binding 8/982 76/18639 0.105263157894737 1.9979633401222 0.0462269848023734 0.371238247182137 GO:0005507 copper ion binding 7/982 63/18639 0.111111111111111 2.10896130346232 0.0471084132366803 0.372967917480319 GO:0008083 growth factor activity 14/982 162/18639 0.0864197530864197 1.64030323602625 0.0472588718461199 0.372967917480319 GO:0003712 transcription coregulator activity 35/982 495/18639 0.0707070707070707 1.34206628402148 0.0475141120927993 0.372967917480319 GO:0019841 retinol binding 3/982 16/18639 0.1875 3.55887219959267 0.0488560283662262 0.380639504584628 GO:0008320 protein transmembrane transporter activity 4/982 27/18639 0.148148148148148 2.81194840461643 0.0511970390467061 0.395923768627861 GO:0019888 protein phosphatase regulator activity 10/982 107/18639 0.0934579439252336 1.77389268515522 0.0555845600568266 0.417113068650358 GO:0033293 monocarboxylic acid binding 8/982 79/18639 0.10126582278481 1.92209131454794 0.0558773644766055 0.417113068650358 GO:0004550 nucleoside diphosphate kinase activity 3/982 17/18639 0.176470588235294 3.34952677608722 0.0570741254882101 0.417113068650358 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/982 17/18639 0.176470588235294 3.34952677608722 0.0570741254882101 0.417113068650358 GO:0030169 low-density lipoprotein particle binding 3/982 17/18639 0.176470588235294 3.34952677608722 0.0570741254882101 0.417113068650358 GO:0046625 sphingolipid binding 4/982 28/18639 0.142857142857143 2.71152167588013 0.0573361913110692 0.417113068650358 GO:0051393 alpha-actinin binding 4/982 28/18639 0.142857142857143 2.71152167588013 0.0573361913110692 0.417113068650358 GO:0051537 2 iron, 2 sulfur cluster binding 4/982 28/18639 0.142857142857143 2.71152167588013 0.0573361913110692 0.417113068650358 GO:0050997 quaternary ammonium group binding 5/982 40/18639 0.125 2.37258146639511 0.0575328370552218 0.417113068650358 GO:0140318 protein transporter activity 5/982 41/18639 0.121951219512195 2.31471362575133 0.0628090582533787 0.451268267698159 GO:0016829 lyase activity 16/982 200/18639 0.08 1.51845213849287 0.0635992605860405 0.451268267698159 GO:0008308 voltage-gated monoatomic anion channel activity 3/982 18/18639 0.166666666666667 3.16344195519348 0.0658983194089983 0.451268267698159 GO:0031690 adrenergic receptor binding 3/982 18/18639 0.166666666666667 3.16344195519348 0.0658983194089983 0.451268267698159 GO:0035615 clathrin adaptor activity 3/982 18/18639 0.166666666666667 3.16344195519348 0.0658983194089983 0.451268267698159 GO:0070064 proline-rich region binding 3/982 18/18639 0.166666666666667 3.16344195519348 0.0658983194089983 0.451268267698159 GO:0098641 cadherin binding involved in cell-cell adhesion 3/982 18/18639 0.166666666666667 3.16344195519348 0.0658983194089983 0.451268267698159 GO:1901611 phosphatidylglycerol binding 3/982 18/18639 0.166666666666667 3.16344195519348 0.0658983194089983 0.451268267698159 GO:0030246 carbohydrate binding 21/982 280/18639 0.075 1.42354887983707 0.0661341426799026 0.451268267698159 GO:0031492 nucleosomal DNA binding 5/982 42/18639 0.119047619047619 2.25960139656677 0.0683485438171296 0.463349868474567 GO:0008200 ion channel inhibitor activity 5/982 43/18639 0.116279069767442 2.20705252687917 0.0741494807206458 0.491356078622164 GO:0097110 scaffold protein binding 7/982 70/18639 0.1 1.89806517311609 0.0748906952050874 0.491356078622164 GO:0005346 purine ribonucleotide transmembrane transporter activity 3/982 19/18639 0.157894736842105 2.9969450101833 0.0753036135819408 0.491356078622164 GO:0030506 ankyrin binding 3/982 19/18639 0.157894736842105 2.9969450101833 0.0753036135819408 0.491356078622164 GO:0043395 heparan sulfate proteoglycan binding 3/982 19/18639 0.157894736842105 2.9969450101833 0.0753036135819408 0.491356078622164 GO:0097001 ceramide binding 3/982 19/18639 0.157894736842105 2.9969450101833 0.0753036135819408 0.491356078622164 GO:0008327 methyl-CpG binding 4/982 31/18639 0.129032258064516 2.44911635240786 0.0779823319507886 0.505674251904493 GO:0099106 ion channel regulator activity 13/982 160/18639 0.08125 1.54217795315682 0.0801780973653187 0.516703294132054 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 8/982 86/18639 0.0930232558139535 1.76564202150334 0.0830655039474762 0.531845773384207 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/982 20/18639 0.15 2.84709775967413 0.0852627248967594 0.531845773384207 GO:0022884 macromolecule transmembrane transporter activity 4/982 32/18639 0.125 2.37258146639511 0.0855843773261942 0.531845773384207 GO:0070717 poly-purine tract binding 4/982 32/18639 0.125 2.37258146639511 0.0855843773261942 0.531845773384207 GO:0071813 lipoprotein particle binding 4/982 32/18639 0.125 2.37258146639511 0.0855843773261942 0.531845773384207 GO:0071814 protein-lipid complex binding 4/982 32/18639 0.125 2.37258146639511 0.0855843773261942 0.531845773384207 GO:0004090 carbonyl reductase (NADPH) activity 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0004935 adrenergic receptor activity 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0005345 purine nucleobase transmembrane transporter activity 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0008239 dipeptidyl-peptidase activity 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0015643 toxic substance binding 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0016783 sulfurtransferase activity 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0031419 cobalamin binding 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0033204 ribonuclease P RNA binding 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0035374 chondroitin sulfate binding 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0047429 nucleoside triphosphate diphosphatase activity 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0097177 mitochondrial ribosome binding 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0141109 transporter activator activity 2/982 10/18639 0.2 3.79613034623218 0.0942334114385464 0.543997522086668 GO:0048029 monosaccharide binding 7/982 74/18639 0.0945945945945946 1.79546705565036 0.094313746645294 0.543997522086668 GO:0140312 cargo adaptor activity 3/982 21/18639 0.142857142857143 2.71152167588013 0.0957465630067786 0.549227537247675 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 6/982 61/18639 0.0983606557377049 1.86694935060599 0.101037765646999 0.57641217123206 GO:0017022 myosin binding 7/982 76/18639 0.0921052631578947 1.74821792260692 0.104979665350865 0.586778635566018 GO:0034062 5'-3' RNA polymerase activity 3/982 22/18639 0.136363636363636 2.58827069061285 0.106724656727273 0.586778635566018 GO:0070034 telomerase RNA binding 3/982 22/18639 0.136363636363636 2.58827069061285 0.106724656727273 0.586778635566018 GO:0097747 RNA polymerase activity 3/982 22/18639 0.136363636363636 2.58827069061285 0.106724656727273 0.586778635566018 GO:0030414 peptidase inhibitor activity 13/982 169/18639 0.0769230769230769 1.46005013316622 0.110417360839203 0.586778635566018 GO:0015205 nucleobase transmembrane transporter activity 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0034511 U3 snoRNA binding 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0034713 type I transforming growth factor beta receptor binding 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0050786 RAGE receptor binding 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0070697 activin receptor binding 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0097493 structural molecule activity conferring elasticity 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0140537 transcription regulator activator activity 2/982 11/18639 0.181818181818182 3.4510275874838 0.111285603297003 0.586778635566018 GO:0000295 adenine nucleotide transmembrane transporter activity 3/982 23/18639 0.130434782608696 2.47573718232533 0.118165532203789 0.61992369658671 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/982 36/18639 0.111111111111111 2.10896130346232 0.11934036764497 0.622956719106745 GO:0023023 MHC protein complex binding 4/982 37/18639 0.108108108108108 2.05196234931469 0.128558493288134 0.640371119121417 GO:0004526 ribonuclease P activity 2/982 12/18639 0.166666666666667 3.16344195519348 0.129056206158817 0.640371119121417 GO:0005165 neurotrophin receptor binding 2/982 12/18639 0.166666666666667 3.16344195519348 0.129056206158817 0.640371119121417 GO:0015368 calcium:monoatomic cation antiporter activity 2/982 12/18639 0.166666666666667 3.16344195519348 0.129056206158817 0.640371119121417 GO:0016208 AMP binding 2/982 12/18639 0.166666666666667 3.16344195519348 0.129056206158817 0.640371119121417 GO:0016801 hydrolase activity, acting on ether bonds 2/982 12/18639 0.166666666666667 3.16344195519348 0.129056206158817 0.640371119121417 GO:0016803 ether hydrolase activity 2/982 12/18639 0.166666666666667 3.16344195519348 0.129056206158817 0.640371119121417 GO:0031543 peptidyl-proline dioxygenase activity 2/982 12/18639 0.166666666666667 3.16344195519348 0.129056206158817 0.640371119121417 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/982 12/18639 0.166666666666667 3.16344195519348 0.129056206158817 0.640371119121417 GO:0003743 translation initiation factor activity 5/982 51/18639 0.0980392156862745 1.86084820893734 0.129535395719983 0.640371119121417 GO:0030544 Hsp70 protein binding 5/982 51/18639 0.0980392156862745 1.86084820893734 0.129535395719983 0.640371119121417 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/982 24/18639 0.125 2.37258146639511 0.130037047177912 0.640371119121417 GO:0005080 protein kinase C binding 5/982 52/18639 0.0961538461538462 1.82506266645778 0.137502981008107 0.673958273110159 GO:0015662 P-type ion transporter activity 3/982 25/18639 0.12 2.27767820773931 0.142306685333865 0.682936580386153 GO:0017025 TBP-class protein binding 3/982 25/18639 0.12 2.27767820773931 0.142306685333865 0.682936580386153 GO:0019211 phosphatase activator activity 3/982 25/18639 0.12 2.27767820773931 0.142306685333865 0.682936580386153 GO:0140358 P-type transmembrane transporter activity 3/982 25/18639 0.12 2.27767820773931 0.142306685333865 0.682936580386153 GO:0004866 endopeptidase inhibitor activity 12/982 161/18639 0.0745341614906832 1.41470696132876 0.143054119884835 0.682936580386153 GO:0140296 general transcription initiation factor binding 5/982 53/18639 0.0943396226415094 1.79062752180763 0.145680826186683 0.682936580386153 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/982 53/18639 0.0943396226415094 1.79062752180763 0.145680826186683 0.682936580386153 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/982 13/18639 0.153846153846154 2.92010026633245 0.147422380111724 0.682936580386153 GO:0019855 calcium channel inhibitor activity 2/982 13/18639 0.153846153846154 2.92010026633245 0.147422380111724 0.682936580386153 GO:0030955 potassium ion binding 2/982 13/18639 0.153846153846154 2.92010026633245 0.147422380111724 0.682936580386153 GO:0031432 titin binding 2/982 13/18639 0.153846153846154 2.92010026633245 0.147422380111724 0.682936580386153 GO:1901338 catecholamine binding 2/982 13/18639 0.153846153846154 2.92010026633245 0.147422380111724 0.682936580386153 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/982 39/18639 0.102564102564103 1.9467335108883 0.147838761654474 0.682936580386153 GO:0004860 protein kinase inhibitor activity 7/982 84/18639 0.0833333333333333 1.58172097759674 0.153670384626477 0.700256511791055 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/982 54/18639 0.0925925925925926 1.75746775288527 0.15406127802417 0.700256511791055 GO:0051287 NAD binding 5/982 54/18639 0.0925925925925926 1.75746775288527 0.15406127802417 0.700256511791055 GO:0015216 purine nucleotide transmembrane transporter activity 3/982 26/18639 0.115384615384615 2.19007519974933 0.15494181439055 0.700256511791055 GO:0034237 protein kinase A regulatory subunit binding 3/982 26/18639 0.115384615384615 2.19007519974933 0.15494181439055 0.700256511791055 GO:0030331 nuclear estrogen receptor binding 4/982 40/18639 0.1 1.89806517311609 0.157872753276613 0.704355360772581 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/982 40/18639 0.1 1.89806517311609 0.157872753276613 0.704355360772581 GO:0071855 neuropeptide receptor binding 4/982 40/18639 0.1 1.89806517311609 0.157872753276613 0.704355360772581 GO:0005161 platelet-derived growth factor receptor binding 2/982 14/18639 0.142857142857143 2.71152167588013 0.166272211764831 0.707960467519489 GO:0005344 oxygen carrier activity 2/982 14/18639 0.142857142857143 2.71152167588013 0.166272211764831 0.707960467519489 GO:0008191 metalloendopeptidase inhibitor activity 2/982 14/18639 0.142857142857143 2.71152167588013 0.166272211764831 0.707960467519489 GO:0008331 high voltage-gated calcium channel activity 2/982 14/18639 0.142857142857143 2.71152167588013 0.166272211764831 0.707960467519489 GO:0019992 diacylglycerol binding 2/982 14/18639 0.142857142857143 2.71152167588013 0.166272211764831 0.707960467519489 GO:0042043 neurexin family protein binding 2/982 14/18639 0.142857142857143 2.71152167588013 0.166272211764831 0.707960467519489 GO:0042813 Wnt receptor activity 2/982 14/18639 0.142857142857143 2.71152167588013 0.166272211764831 0.707960467519489 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/982 14/18639 0.142857142857143 2.71152167588013 0.166272211764831 0.707960467519489 GO:1901612 cardiolipin binding 2/982 14/18639 0.142857142857143 2.71152167588013 0.166272211764831 0.707960467519489 GO:0004364 glutathione transferase activity 3/982 27/18639 0.111111111111111 2.10896130346232 0.16790991130853 0.707960467519489 GO:0005044 scavenger receptor activity 3/982 27/18639 0.111111111111111 2.10896130346232 0.16790991130853 0.707960467519489 GO:0023026 MHC class II protein complex binding 3/982 27/18639 0.111111111111111 2.10896130346232 0.16790991130853 0.707960467519489 GO:0017080 sodium channel regulator activity 4/982 41/18639 0.0975609756097561 1.85177090060106 0.168149909495341 0.707960467519489 GO:0019842 vitamin binding 11/982 150/18639 0.0733333333333333 1.39191446028513 0.168174517188538 0.707960467519489 GO:0005253 monoatomic anion channel activity 8/982 103/18639 0.0776699029126214 1.47422537717755 0.175762589645743 0.736932303574922 GO:0046906 tetrapyrrole binding 11/982 152/18639 0.0723684210526316 1.37359979633401 0.178651376193643 0.743092232393728 GO:0042056 chemoattractant activity 4/982 42/18639 0.0952380952380952 1.80768111725342 0.178655316408837 0.743092232393728 GO:0045499 chemorepellent activity 3/982 28/18639 0.107142857142857 2.0336412569101 0.181178757708225 0.750597710505505 GO:0005523 tropomyosin binding 2/982 15/18639 0.133333333333333 2.53075356415479 0.185503905779356 0.759176208357356 GO:0031005 filamin binding 2/982 15/18639 0.133333333333333 2.53075356415479 0.185503905779356 0.759176208357356 GO:0034483 heparan sulfate sulfotransferase activity 2/982 15/18639 0.133333333333333 2.53075356415479 0.185503905779356 0.759176208357356 GO:0043539 protein serine/threonine kinase activator activity 6/982 73/18639 0.0821917808219178 1.56005356694473 0.186158150708317 0.759176208357356 GO:0031406 carboxylic acid binding 13/982 187/18639 0.0695187165775401 1.31951054815557 0.188198412477673 0.764510282594128 GO:0048156 tau protein binding 4/982 43/18639 0.0930232558139535 1.76564202150334 0.189373863658908 0.766303541317441 GO:0031491 nucleosome binding 6/982 74/18639 0.0810810810810811 1.53897176198602 0.194262068713878 0.780164867331312 GO:0019210 kinase inhibitor activity 7/982 90/18639 0.0777777777777778 1.47627291242363 0.195879387860986 0.780164867331312 GO:0043177 organic acid binding 13/982 189/18639 0.0687830687830688 1.30554747357191 0.198151062889119 0.780164867331312 GO:0070063 RNA polymerase binding 5/982 59/18639 0.0847457627118644 1.6085298077255 0.198714620557928 0.780164867331312 GO:0016790 thiolester hydrolase activity 4/982 44/18639 0.0909090909090909 1.7255137937419 0.200290314393508 0.780164867331312 GO:0019205 nucleobase-containing compound kinase activity 4/982 44/18639 0.0909090909090909 1.7255137937419 0.200290314393508 0.780164867331312 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/982 44/18639 0.0909090909090909 1.7255137937419 0.200290314393508 0.780164867331312 GO:0005516 calmodulin binding 14/982 207/18639 0.0676328502415459 1.28371557602054 0.203732618147977 0.780164867331312 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/982 16/18639 0.125 2.37258146639511 0.205025031124089 0.780164867331312 GO:0008142 oxysterol binding 2/982 16/18639 0.125 2.37258146639511 0.205025031124089 0.780164867331312 GO:0034450 ubiquitin-ubiquitin ligase activity 2/982 16/18639 0.125 2.37258146639511 0.205025031124089 0.780164867331312 GO:0043023 ribosomal large subunit binding 2/982 16/18639 0.125 2.37258146639511 0.205025031124089 0.780164867331312 GO:0001098 basal transcription machinery binding 5/982 60/18639 0.0833333333333333 1.58172097759674 0.208134736768524 0.780164867331312 GO:0001099 basal RNA polymerase II transcription machinery binding 5/982 60/18639 0.0833333333333333 1.58172097759674 0.208134736768524 0.780164867331312 GO:0001965 G-protein alpha-subunit binding 3/982 30/18639 0.1 1.89806517311609 0.208492335235092 0.780164867331312 GO:0008187 poly-pyrimidine tract binding 3/982 30/18639 0.1 1.89806517311609 0.208492335235092 0.780164867331312 GO:0015215 nucleotide transmembrane transporter activity 3/982 30/18639 0.1 1.89806517311609 0.208492335235092 0.780164867331312 GO:0016769 transferase activity, transferring nitrogenous groups 3/982 30/18639 0.1 1.89806517311609 0.208492335235092 0.780164867331312 GO:0022839 monoatomic ion-gated channel activity 3/982 30/18639 0.1 1.89806517311609 0.208492335235092 0.780164867331312 GO:0033612 receptor serine/threonine kinase binding 3/982 30/18639 0.1 1.89806517311609 0.208492335235092 0.780164867331312 GO:0048019 receptor antagonist activity 3/982 30/18639 0.1 1.89806517311609 0.208492335235092 0.780164867331312 GO:0043178 alcohol binding 7/982 92/18639 0.0760869565217391 1.44418002302311 0.210878790229237 0.785375455170617 GO:0042605 peptide antigen binding 4/982 45/18639 0.0888888888888889 1.68716904276986 0.211389370596689 0.785375455170617 GO:0140297 DNA-binding transcription factor binding 30/982 488/18639 0.0614754098360656 1.16684334412874 0.21478489115098 0.795161086388733 GO:0017147 Wnt-protein binding 3/982 31/18639 0.0967741935483871 1.83683726430589 0.222475549872696 0.800822179379057 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0004549 tRNA-specific ribonuclease activity 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0005092 GDP-dissociation inhibitor activity 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0016018 cyclosporin A binding 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0048038 quinone binding 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0051787 misfolded protein binding 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0070403 NAD+ binding 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0070492 oligosaccharide binding 2/982 17/18639 0.117647058823529 2.23301785072481 0.224751818542207 0.800822179379057 GO:0042562 hormone binding 7/982 94/18639 0.074468085106383 1.4134527884907 0.226286895412027 0.803549383708016 GO:1902936 phosphatidylinositol bisphosphate binding 8/982 111/18639 0.0720720720720721 1.36797489954313 0.230627883164624 0.816188169572431 GO:0030515 snoRNA binding 3/982 32/18639 0.09375 1.77943609979633 0.236636705653369 0.829022552691667 GO:0031369 translation initiation factor binding 3/982 32/18639 0.09375 1.77943609979633 0.236636705653369 0.829022552691667 GO:0043425 bHLH transcription factor binding 3/982 32/18639 0.09375 1.77943609979633 0.236636705653369 0.829022552691667 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/982 18/18639 0.111111111111111 2.10896130346232 0.244608505933858 0.842785426614487 GO:0004970 glutamate-gated receptor activity 2/982 18/18639 0.111111111111111 2.10896130346232 0.244608505933858 0.842785426614487 GO:0017128 phospholipid scramblase activity 2/982 18/18639 0.111111111111111 2.10896130346232 0.244608505933858 0.842785426614487 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/982 18/18639 0.111111111111111 2.10896130346232 0.244608505933858 0.842785426614487 GO:1990381 ubiquitin-specific protease binding 2/982 18/18639 0.111111111111111 2.10896130346232 0.244608505933858 0.842785426614487 GO:0048306 calcium-dependent protein binding 6/982 80/18639 0.075 1.42354887983707 0.24540878322874 0.842785426614487 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/982 33/18639 0.0909090909090909 1.7255137937419 0.250947182590819 0.858979864343657 GO:0001618 virus receptor activity 6/982 81/18639 0.0740740740740741 1.40597420230821 0.254295601556616 0.867596758251982 GO:0019207 kinase regulator activity 18/982 287/18639 0.0627177700348432 1.1904241503864 0.255679722635343 0.86851425638717 GO:0038024 cargo receptor activity 5/982 65/18639 0.0769230769230769 1.46005013316622 0.257181545817103 0.86851425638717 GO:0140272 exogenous protein binding 6/982 82/18639 0.0731707317073171 1.3888281754508 0.263268956236324 0.86851425638717 GO:0003756 protein disulfide isomerase activity 2/982 19/18639 0.105263157894737 1.9979633401222 0.264526728563496 0.86851425638717 GO:0005229 intracellularly calcium-gated chloride channel activity 2/982 19/18639 0.105263157894737 1.9979633401222 0.264526728563496 0.86851425638717 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/982 19/18639 0.105263157894737 1.9979633401222 0.264526728563496 0.86851425638717 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/982 19/18639 0.105263157894737 1.9979633401222 0.264526728563496 0.86851425638717 GO:0031420 alkali metal ion binding 2/982 19/18639 0.105263157894737 1.9979633401222 0.264526728563496 0.86851425638717 GO:0042577 lipid phosphatase activity 2/982 19/18639 0.105263157894737 1.9979633401222 0.264526728563496 0.86851425638717 GO:0070003 threonine-type peptidase activity 2/982 19/18639 0.105263157894737 1.9979633401222 0.264526728563496 0.86851425638717 GO:0141147 intracellularly calcium-gated channel activity 2/982 19/18639 0.105263157894737 1.9979633401222 0.264526728563496 0.86851425638717 GO:0030332 cyclin binding 3/982 34/18639 0.0882352941176471 1.67476338804361 0.265379356118302 0.86851425638717 GO:0051427 hormone receptor binding 3/982 34/18639 0.0882352941176471 1.67476338804361 0.265379356118302 0.86851425638717 GO:0015605 organophosphate ester transmembrane transporter activity 4/982 50/18639 0.08 1.51845213849287 0.269091298939345 0.877910362789613 GO:0005254 chloride channel activity 6/982 83/18639 0.072289156626506 1.37209530586705 0.27232239914698 0.885684064515412 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/982 67/18639 0.0746268656716418 1.41646654710156 0.277534785193303 0.899833278701269 GO:0001972 retinoic acid binding 2/982 20/18639 0.1 1.89806517311609 0.284444951193133 0.910921868238131 GO:0031418 L-ascorbic acid binding 2/982 20/18639 0.1 1.89806517311609 0.284444951193133 0.910921868238131 GO:0042288 MHC class I protein binding 2/982 20/18639 0.1 1.89806517311609 0.284444951193133 0.910921868238131 GO:0052745 inositol phosphate phosphatase activity 2/982 20/18639 0.1 1.89806517311609 0.284444951193133 0.910921868238131 GO:1990841 promoter-specific chromatin binding 5/982 68/18639 0.0735294117647059 1.39563615670301 0.287831686683443 0.91894887124622 GO:0051020 GTPase binding 19/982 315/18639 0.0603174603174603 1.14486470759383 0.304236356128705 0.956039667274779 GO:0009975 cyclase activity 2/982 21/18639 0.0952380952380952 1.80768111725342 0.304307939423275 0.956039667274779 GO:0051428 peptide hormone receptor binding 2/982 21/18639 0.0952380952380952 1.80768111725342 0.304307939423275 0.956039667274779 GO:0061891 calcium ion sensor activity 2/982 21/18639 0.0952380952380952 1.80768111725342 0.304307939423275 0.956039667274779 GO:0072542 protein phosphatase activator activity 2/982 21/18639 0.0952380952380952 1.80768111725342 0.304307939423275 0.956039667274779 GO:0051018 protein kinase A binding 4/982 53/18639 0.0754716981132075 1.43250201744611 0.304943686975576 0.956039667274779 GO:0003697 single-stranded DNA binding 8/982 121/18639 0.0661157024793388 1.25491912272138 0.306200223620251 0.95710489059743 GO:0016782 transferase activity, transferring sulphur-containing groups 5/982 70/18639 0.0714285714285714 1.35576083794006 0.308620437973714 0.961790260431515 GO:0003925 G protein activity 4/982 54/18639 0.0740740740740741 1.40597420230821 0.317014279691689 0.98056854034702 GO:0005109 frizzled binding 3/982 38/18639 0.0789473684210526 1.49847250509165 0.323810076973202 0.98056854034702 GO:0043531 ADP binding 3/982 38/18639 0.0789473684210526 1.49847250509165 0.323810076973202 0.98056854034702 GO:0140517 protein-RNA adaptor activity 2/982 22/18639 0.0909090909090909 1.7255137937419 0.324066267692875 0.98056854034702 GO:0140784 metal ion sensor activity 2/982 22/18639 0.0909090909090909 1.7255137937419 0.324066267692875 0.98056854034702 GO:0020037 heme binding 9/982 142/18639 0.0633802816901408 1.20299905338344 0.333171613538057 0.98056854034702 GO:0005158 insulin receptor binding 2/982 23/18639 0.0869565217391304 1.65049145488356 0.343675861548979 0.98056854034702 GO:0016849 phosphorus-oxygen lyase activity 2/982 23/18639 0.0869565217391304 1.65049145488356 0.343675861548979 0.98056854034702 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/982 23/18639 0.0869565217391304 1.65049145488356 0.343675861548979 0.98056854034702 GO:0019903 protein phosphatase binding 9/982 144/18639 0.0625 1.18629073319756 0.348110269544329 0.98056854034702 GO:0019955 cytokine binding 9/982 144/18639 0.0625 1.18629073319756 0.348110269544329 0.98056854034702 GO:0004620 phospholipase activity 7/982 109/18639 0.0642201834862385 1.21894093686354 0.351127099828529 0.98056854034702 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/982 40/18639 0.075 1.42354887983707 0.353117726220559 0.98056854034702 GO:0015932 nucleobase-containing compound transmembrane transporter activity 4/982 57/18639 0.0701754385964912 1.33197556008147 0.353399744588286 0.98056854034702 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 8/982 128/18639 0.0625 1.18629073319756 0.361915924805253 0.98056854034702 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/982 24/18639 0.0833333333333333 1.58172097759674 0.363097571946349 0.98056854034702 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/982 24/18639 0.0833333333333333 1.58172097759674 0.363097571946349 0.98056854034702 GO:0005315 phosphate transmembrane transporter activity 2/982 24/18639 0.0833333333333333 1.58172097759674 0.363097571946349 0.98056854034702 GO:0015295 solute:proton symporter activity 2/982 24/18639 0.0833333333333333 1.58172097759674 0.363097571946349 0.98056854034702 GO:0030215 semaphorin receptor binding 2/982 24/18639 0.0833333333333333 1.58172097759674 0.363097571946349 0.98056854034702 GO:0070300 phosphatidic acid binding 2/982 24/18639 0.0833333333333333 1.58172097759674 0.363097571946349 0.98056854034702 GO:0001530 lipopolysaccharide binding 3/982 41/18639 0.0731707317073171 1.3888281754508 0.367720448593602 0.98056854034702 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/982 41/18639 0.0731707317073171 1.3888281754508 0.367720448593602 0.98056854034702 GO:0008227 G protein-coupled amine receptor activity 3/982 41/18639 0.0731707317073171 1.3888281754508 0.367720448593602 0.98056854034702 GO:0042287 MHC protein binding 3/982 41/18639 0.0731707317073171 1.3888281754508 0.367720448593602 0.98056854034702 GO:0140828 metal cation:monoatomic cation antiporter activity 3/982 41/18639 0.0731707317073171 1.3888281754508 0.367720448593602 0.98056854034702 GO:0019887 protein kinase regulator activity 15/982 255/18639 0.0588235294117647 1.11650892536241 0.367771854725912 0.98056854034702 GO:0015085 calcium ion transmembrane transporter activity 9/982 147/18639 0.0612244897959184 1.16208071823434 0.370685882396549 0.98056854034702 GO:0003713 transcription coactivator activity 15/982 256/18639 0.05859375 1.11214756237271 0.373481430948484 0.98056854034702 GO:0005200 structural constituent of cytoskeleton 7/982 112/18639 0.0625 1.18629073319756 0.377206217933483 0.98056854034702 GO:0015459 potassium channel regulator activity 4/982 59/18639 0.0677966101694915 1.2868238461804 0.377677564517911 0.98056854034702 GO:0036002 pre-mRNA binding 4/982 59/18639 0.0677966101694915 1.2868238461804 0.377677564517911 0.98056854034702 GO:0016298 lipase activity 8/982 130/18639 0.0615384615384615 1.16804010653298 0.378048373646006 0.98056854034702 GO:0019209 kinase activator activity 9/982 148/18639 0.0608108108108108 1.15422882148951 0.378243835117173 0.98056854034702 GO:0048487 beta-tubulin binding 3/982 42/18639 0.0714285714285714 1.35576083794006 0.382263920300123 0.98056854034702 GO:0015271 outward rectifier potassium channel activity 2/982 25/18639 0.08 1.51845213849287 0.382296779477868 0.98056854034702 GO:0120020 cholesterol transfer activity 2/982 25/18639 0.08 1.51845213849287 0.382296779477868 0.98056854034702 GO:0008509 monoatomic anion transmembrane transporter activity 9/982 149/18639 0.0604026845637584 1.14648231933187 0.385813244147228 0.98056854034702 GO:0046982 protein heterodimerization activity 21/982 369/18639 0.0569105691056911 1.08019969201729 0.389433584195176 0.98056854034702 GO:0005179 hormone activity 8/982 132/18639 0.0606060606060606 1.15034252916127 0.394222610105581 0.98056854034702 GO:0001664 G protein-coupled receptor binding 17/982 297/18639 0.0572390572390572 1.08643461087453 0.397796729568179 0.98056854034702 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/982 26/18639 0.0769230769230769 1.46005013316622 0.401243026568479 0.98056854034702 GO:0005160 transforming growth factor beta receptor binding 2/982 26/18639 0.0769230769230769 1.46005013316622 0.401243026568479 0.98056854034702 GO:0005227 calcium-activated cation channel activity 2/982 26/18639 0.0769230769230769 1.46005013316622 0.401243026568479 0.98056854034702 GO:0008066 glutamate receptor activity 2/982 26/18639 0.0769230769230769 1.46005013316622 0.401243026568479 0.98056854034702 GO:0008198 ferrous iron binding 2/982 26/18639 0.0769230769230769 1.46005013316622 0.401243026568479 0.98056854034702 GO:0019865 immunoglobulin binding 2/982 26/18639 0.0769230769230769 1.46005013316622 0.401243026568479 0.98056854034702 GO:0097602 cullin family protein binding 2/982 26/18639 0.0769230769230769 1.46005013316622 0.401243026568479 0.98056854034702 GO:0015026 coreceptor activity 4/982 61/18639 0.0655737704918033 1.24463290040399 0.401864313880154 0.98056854034702 GO:0001221 transcription coregulator binding 7/982 115/18639 0.0608695652173913 1.15534401841849 0.403364036040669 0.98056854034702 GO:0017124 SH3 domain binding 7/982 115/18639 0.0608695652173913 1.15534401841849 0.403364036040669 0.98056854034702 GO:0042626 ATPase-coupled transmembrane transporter activity 6/982 98/18639 0.0612244897959184 1.16208071823434 0.413436170766808 0.98056854034702 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0005131 growth hormone receptor binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0005337 nucleoside transmembrane transporter activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0015187 glycine transmembrane transporter activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0015279 store-operated calcium channel activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0016868 intramolecular phosphotransferase activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0019531 oxalate transmembrane transporter activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0019911 structural constituent of myelin sheath 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0031434 mitogen-activated protein kinase kinase binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0031720 haptoglobin binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0031996 thioesterase binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0032052 bile acid binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0032356 oxidized DNA binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0043295 glutathione binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0051378 serotonin binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0051880 G-quadruplex DNA binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0070097 delta-catenin binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0098505 G-rich strand telomeric DNA binding 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0140940 histone H2A methyltransferase activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:1990259 histone H2AQ104 methyltransferase activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:1990757 ubiquitin ligase activator activity 1/982 10/18639 0.1 1.89806517311609 0.418051232163516 0.98056854034702 GO:0005104 fibroblast growth factor receptor binding 2/982 27/18639 0.0740740740740741 1.40597420230821 0.419909675789274 0.98056854034702 GO:0008266 poly(U) RNA binding 2/982 27/18639 0.0740740740740741 1.40597420230821 0.419909675789274 0.98056854034702 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/982 27/18639 0.0740740740740741 1.40597420230821 0.419909675789274 0.98056854034702 GO:0035255 ionotropic glutamate receptor binding 2/982 27/18639 0.0740740740740741 1.40597420230821 0.419909675789274 0.98056854034702 GO:0051539 4 iron, 4 sulfur cluster binding 3/982 45/18639 0.0666666666666667 1.26537678207739 0.425369715783361 0.98056854034702 GO:0005244 voltage-gated monoatomic ion channel activity 10/982 173/18639 0.0578034682080925 1.09714749891103 0.428100217388934 0.98056854034702 GO:0005525 GTP binding 21/982 378/18639 0.0555555555555556 1.05448065173116 0.432997325132983 0.98056854034702 GO:0016922 nuclear receptor binding 8/982 137/18639 0.0583941605839416 1.10835922517728 0.434659125162888 0.98056854034702 GO:0004536 DNA nuclease activity 4/982 64/18639 0.0625 1.18629073319756 0.437791063416309 0.98056854034702 GO:0005085 guanyl-nucleotide exchange factor activity 13/982 230/18639 0.0565217391304348 1.07281944567431 0.437869419437336 0.98056854034702 GO:0005242 inward rectifier potassium channel activity 2/982 28/18639 0.0714285714285714 1.35576083794006 0.43827359256474 0.98056854034702 GO:0019789 SUMO transferase activity 2/982 28/18639 0.0714285714285714 1.35576083794006 0.43827359256474 0.98056854034702 GO:0046875 ephrin receptor binding 2/982 28/18639 0.0714285714285714 1.35576083794006 0.43827359256474 0.98056854034702 GO:0050698 proteoglycan sulfotransferase activity 2/982 28/18639 0.0714285714285714 1.35576083794006 0.43827359256474 0.98056854034702 GO:0097718 disordered domain specific binding 2/982 28/18639 0.0714285714285714 1.35576083794006 0.43827359256474 0.98056854034702 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/982 46/18639 0.0652173913043478 1.23786859116267 0.439512551733679 0.98056854034702 GO:0030291 protein serine/threonine kinase inhibitor activity 3/982 46/18639 0.0652173913043478 1.23786859116267 0.439512551733679 0.98056854034702 GO:0022832 voltage-gated channel activity 10/982 175/18639 0.0571428571428571 1.08460867035205 0.442408420273233 0.98056854034702 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 15/982 268/18639 0.0559701492537313 1.06234991032617 0.442615151587524 0.98056854034702 GO:0030165 PDZ domain binding 5/982 83/18639 0.0602409638554217 1.14341275488921 0.445671488308658 0.98056854034702 GO:0008514 organic anion transmembrane transporter activity 15/982 269/18639 0.0557620817843866 1.05840065415395 0.44838985503283 0.98056854034702 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0000099 sulfur amino acid transmembrane transporter activity 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0004016 adenylate cyclase activity 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0005114 type II transforming growth factor beta receptor binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0005536 D-glucose binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0008172 S-methyltransferase activity 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0008432 JUN kinase binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0008526 phosphatidylinositol transfer activity 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0015173 aromatic amino acid transmembrane transporter activity 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0019215 intermediate filament binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0042608 T cell receptor binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0047676 arachidonate-CoA ligase activity 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0048185 activin binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0050998 nitric-oxide synthase binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0140031 phosphorylation-dependent protein binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0180030 inositol phosphate kinase activity 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:1900750 oligopeptide binding 1/982 11/18639 0.0909090909090909 1.7255137937419 0.448727795050167 0.98056854034702 GO:0160215 deacylase activity 4/982 65/18639 0.0615384615384615 1.16804010653298 0.449634310471995 0.98056854034702 GO:0030295 protein kinase activator activity 8/982 139/18639 0.0575539568345324 1.09241161042653 0.450764380373739 0.98056854034702 GO:0042578 phosphoric ester hydrolase activity 20/982 363/18639 0.0550964187327824 1.04576593560115 0.451111159337784 0.98056854034702 GO:0015171 amino acid transmembrane transporter activity 6/982 102/18639 0.0588235294117647 1.11650892536241 0.451244058188562 0.98056854034702 GO:0061749 forked DNA-dependent helicase activity 3/982 47/18639 0.0638297872340425 1.21153096156346 0.453519714707685 0.98056854034702 GO:0099095 ligand-gated monoatomic anion channel activity 3/982 47/18639 0.0638297872340425 1.21153096156346 0.453519714707685 0.98056854034702 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/982 47/18639 0.0638297872340425 1.21153096156346 0.453519714707685 0.98056854034702 GO:0015108 chloride transmembrane transporter activity 7/982 121/18639 0.0578512396694215 1.09805423238121 0.455456876226037 0.98056854034702 GO:0051117 ATPase binding 5/982 84/18639 0.0595238095238095 1.12980069828339 0.456065286480913 0.98056854034702 GO:0003785 actin monomer binding 2/982 29/18639 0.0689655172413793 1.30901046421799 0.456314850655256 0.98056854034702 GO:0005416 amino acid:monoatomic cation symporter activity 2/982 29/18639 0.0689655172413793 1.30901046421799 0.456314850655256 0.98056854034702 GO:0035250 UDP-galactosyltransferase activity 2/982 29/18639 0.0689655172413793 1.30901046421799 0.456314850655256 0.98056854034702 GO:0009378 four-way junction helicase activity 3/982 48/18639 0.0625 1.18629073319756 0.4673790611275 0.98056854034702 GO:0036121 double-stranded DNA helicase activity 3/982 48/18639 0.0625 1.18629073319756 0.4673790611275 0.98056854034702 GO:0043138 3'-5' DNA helicase activity 3/982 48/18639 0.0625 1.18629073319756 0.4673790611275 0.98056854034702 GO:0004175 endopeptidase activity 22/982 405/18639 0.054320987654321 1.03104774835936 0.472610768429106 0.98056854034702 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/982 30/18639 0.0666666666666667 1.26537678207739 0.474016458899553 0.98056854034702 GO:0051721 protein phosphatase 2A binding 2/982 30/18639 0.0666666666666667 1.26537678207739 0.474016458899553 0.98056854034702 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0003995 acyl-CoA dehydrogenase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0004300 enoyl-CoA hydratase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0004859 phospholipase inhibitor activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0005049 nuclear export signal receptor activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0005247 voltage-gated chloride channel activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0008179 adenylate cyclase binding 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0015269 calcium-activated potassium channel activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0016273 arginine N-methyltransferase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0016274 protein-arginine N-methyltransferase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0017166 vinculin binding 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0035259 nuclear glucocorticoid receptor binding 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0035497 cAMP response element binding 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0036009 protein-glutamine N-methyltransferase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0043047 single-stranded telomeric DNA binding 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0140900 chloride:bicarbonate antiporter activity 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:1990459 transferrin receptor binding 1/982 12/18639 0.0833333333333333 1.58172097759674 0.477788848585745 0.98056854034702 GO:0001222 transcription corepressor binding 3/982 49/18639 0.0612244897959184 1.16208071823434 0.481079424368944 0.98056854034702 GO:0016763 pentosyltransferase activity 3/982 49/18639 0.0612244897959184 1.16208071823434 0.481079424368944 0.98056854034702 GO:0140223 general transcription initiation factor activity 4/982 68/18639 0.0588235294117647 1.11650892536241 0.484648062060342 0.98056854034702 GO:0005164 tumor necrosis factor receptor binding 2/982 31/18639 0.0645161290322581 1.22455817620393 0.491364107797958 0.98056854034702 GO:0005184 neuropeptide hormone activity 2/982 31/18639 0.0645161290322581 1.22455817620393 0.491364107797958 0.98056854034702 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/982 31/18639 0.0645161290322581 1.22455817620393 0.491364107797958 0.98056854034702 GO:0005452 solute:inorganic anion antiporter activity 2/982 31/18639 0.0645161290322581 1.22455817620393 0.491364107797958 0.98056854034702 GO:0072349 modified amino acid transmembrane transporter activity 2/982 31/18639 0.0645161290322581 1.22455817620393 0.491364107797958 0.98056854034702 GO:0032813 tumor necrosis factor receptor superfamily binding 3/982 50/18639 0.06 1.13883910386965 0.494610581311259 0.98056854034702 GO:0005216 monoatomic ion channel activity 24/982 448/18639 0.0535714285714286 1.01682062845505 0.496604162889182 0.98056854034702 GO:0001217 DNA-binding transcription repressor activity 15/982 278/18639 0.0539568345323741 1.02413588477487 0.500059035827702 0.98056854034702 GO:0002161 aminoacyl-tRNA editing activity 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0004993 G protein-coupled serotonin receptor activity 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0005172 vascular endothelial growth factor receptor binding 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0008035 high-density lipoprotein particle binding 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0008253 5'-nucleotidase activity 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0008417 fucosyltransferase activity 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0019104 DNA N-glycosylase activity 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0035673 oligopeptide transmembrane transporter activity 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0070700 BMP receptor binding 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0071837 HMG box domain binding 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0089720 caspase binding 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/982 13/18639 0.0769230769230769 1.46005013316622 0.505319387625247 0.98056854034702 GO:0015103 inorganic anion transmembrane transporter activity 9/982 165/18639 0.0545454545454545 1.03530827624514 0.50621795664236 0.98056854034702 GO:0008378 galactosyltransferase activity 2/982 32/18639 0.0625 1.18629073319756 0.508345934607597 0.98056854034702 GO:0015106 bicarbonate transmembrane transporter activity 2/982 32/18639 0.0625 1.18629073319756 0.508345934607597 0.98056854034702 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/982 32/18639 0.0625 1.18629073319756 0.508345934607597 0.98056854034702 GO:0042910 xenobiotic transmembrane transporter activity 2/982 32/18639 0.0625 1.18629073319756 0.508345934607597 0.98056854034702 GO:0120015 sterol transfer activity 2/982 32/18639 0.0625 1.18629073319756 0.508345934607597 0.98056854034702 GO:0140142 nucleocytoplasmic carrier activity 2/982 32/18639 0.0625 1.18629073319756 0.508345934607597 0.98056854034702 GO:0160041 neuropeptide activity 2/982 32/18639 0.0625 1.18629073319756 0.508345934607597 0.98056854034702 GO:0031490 chromatin DNA binding 7/982 128/18639 0.0546875 1.03800439154786 0.51492542746554 0.98056854034702 GO:0030296 protein tyrosine kinase activator activity 2/982 33/18639 0.0606060606060606 1.15034252916127 0.524952305705454 0.98056854034702 GO:0140416 transcription regulator inhibitor activity 2/982 33/18639 0.0606060606060606 1.15034252916127 0.524952305705454 0.98056854034702 GO:0008234 cysteine-type peptidase activity 10/982 187/18639 0.053475935828877 1.01500811396582 0.526898483275212 0.98056854034702 GO:0031267 small GTPase binding 15/982 283/18639 0.0530035335689046 1.00604161119227 0.528332205823624 0.98056854034702 GO:0004065 arylsulfatase activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0005313 L-glutamate transmembrane transporter activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0008195 phosphatidate phosphatase activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0008474 palmitoyl-(protein) hydrolase activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0008494 translation activator activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0008559 ABC-type xenobiotic transporter activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0015926 glucosidase activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0016530 metallochaperone activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0031404 chloride ion binding 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0043176 amine binding 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0046030 inositol trisphosphate phosphatase activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0070742 C2H2 zinc finger domain binding 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0071933 Arp2/3 complex binding 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0098599 palmitoyl hydrolase activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0098847 sequence-specific single stranded DNA binding 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:1901474 azole transmembrane transporter activity 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:1990825 sequence-specific mRNA binding 1/982 14/18639 0.0714285714285714 1.35576083794006 0.531399939614509 0.98056854034702 GO:0016798 hydrolase activity, acting on glycosyl bonds 7/982 130/18639 0.0538461538461538 1.02203509321636 0.531505312780463 0.98056854034702 GO:0005246 calcium channel regulator activity 3/982 53/18639 0.0566037735849057 1.07437651308458 0.534100005894542 0.98056854034702 GO:0008146 sulfotransferase activity 3/982 53/18639 0.0566037735849057 1.07437651308458 0.534100005894542 0.98056854034702 GO:0016251 RNA polymerase II general transcription initiation factor activity 3/982 53/18639 0.0566037735849057 1.07437651308458 0.534100005894542 0.98056854034702 GO:0019001 guanyl nucleotide binding 21/982 400/18639 0.0525 0.996484215885947 0.538947082263899 0.98056854034702 GO:0032561 guanyl ribonucleotide binding 21/982 400/18639 0.0525 0.996484215885947 0.538947082263899 0.98056854034702 GO:0031072 heat shock protein binding 7/982 131/18639 0.0534351145038168 1.01423329861165 0.539711868699853 0.98056854034702 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/982 34/18639 0.0588235294117647 1.11650892536241 0.541175615054651 0.98056854034702 GO:0019825 oxygen binding 2/982 34/18639 0.0588235294117647 1.11650892536241 0.541175615054651 0.98056854034702 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/982 34/18639 0.0588235294117647 1.11650892536241 0.541175615054651 0.98056854034702 GO:0090482 vitamin transmembrane transporter activity 2/982 34/18639 0.0588235294117647 1.11650892536241 0.541175615054651 0.98056854034702 GO:0051213 dioxygenase activity 5/982 93/18639 0.0537634408602151 1.02046514683661 0.546494457228974 0.98056854034702 GO:0015485 cholesterol binding 3/982 54/18639 0.0555555555555556 1.05448065173116 0.54686975449471 0.98056854034702 GO:0019902 phosphatase binding 10/982 190/18639 0.0526315789473684 0.9989816700611 0.5474049116093 0.98056854034702 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 7/982 132/18639 0.053030303030303 1.00654971301611 0.547859267181132 0.98056854034702 GO:0015291 secondary active transmembrane transporter activity 15/982 287/18639 0.0522648083623693 0.992020125321998 0.550615478941492 0.98056854034702 GO:0003678 DNA helicase activity 4/982 74/18639 0.0540540540540541 1.02598117465735 0.551719315769438 0.98056854034702 GO:0003684 damaged DNA binding 4/982 74/18639 0.0540540540540541 1.02598117465735 0.551719315769438 0.98056854034702 GO:0000774 adenyl-nucleotide exchange factor activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0004089 carbonate dehydratase activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0004467 long-chain fatty acid-CoA ligase activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0004559 alpha-mannosidase activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0008252 nucleotidase activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0015116 sulfate transmembrane transporter activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0015929 hexosaminidase activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0017081 chloride channel regulator activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0033130 acetylcholine receptor binding 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0048531 beta-1,3-galactosyltransferase activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0050780 dopamine receptor binding 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0140161 monocarboxylate:sodium symporter activity 1/982 15/18639 0.0666666666666667 1.26537678207739 0.556106799174163 0.98056854034702 GO:0016229 steroid dehydrogenase activity 2/982 35/18639 0.0571428571428571 1.08460867035205 0.557010097683964 0.98056854034702 GO:0019003 GDP binding 4/982 75/18639 0.0533333333333333 1.01230142566191 0.56244616734694 0.98056854034702 GO:0044183 protein folding chaperone 4/982 75/18639 0.0533333333333333 1.01230142566191 0.56244616734694 0.98056854034702 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 18/982 349/18639 0.0515759312320917 0.978944788426637 0.571784495014876 0.98056854034702 GO:0015297 antiporter activity 7/982 135/18639 0.0518518518518519 0.98418194161575 0.571921682301324 0.98056854034702 GO:0004033 aldo-keto reductase (NADPH) activity 2/982 36/18639 0.0555555555555556 1.05448065173116 0.572451657160524 0.98056854034702 GO:0004190 aspartic-type endopeptidase activity 2/982 36/18639 0.0555555555555556 1.05448065173116 0.572451657160524 0.98056854034702 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/982 36/18639 0.0555555555555556 1.05448065173116 0.572451657160524 0.98056854034702 GO:0000062 fatty-acyl-CoA binding 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0003688 DNA replication origin binding 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0004708 MAP kinase kinase activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0005024 transforming growth factor beta receptor activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0015378 sodium:chloride symporter activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0015385 sodium:proton antiporter activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0015562 efflux transmembrane transporter activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0015923 mannosidase activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0022841 potassium ion leak channel activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0022858 alanine transmembrane transporter activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0055102 lipase inhibitor activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0070411 I-SMAD binding 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0097027 ubiquitin-protein transferase activator activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/982 16/18639 0.0625 1.18629073319756 0.579512250377501 0.98056854034702 GO:0019213 deacetylase activity 2/982 37/18639 0.0540540540540541 1.02598117465735 0.587497706101317 0.983609038650794 GO:0070001 aspartic-type peptidase activity 2/982 37/18639 0.0540540540540541 1.02598117465735 0.587497706101317 0.983609038650794 GO:0005126 cytokine receptor binding 14/982 275/18639 0.0509090909090909 0.966287724495464 0.591526369378312 0.983609038650794 GO:0005249 voltage-gated potassium channel activity 5/982 98/18639 0.0510204081632653 0.968400598528617 0.593513236090994 0.983609038650794 GO:0017116 single-stranded DNA helicase activity 3/982 58/18639 0.0517241379310345 0.981757848163495 0.595825154731626 0.983609038650794 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:0008429 phosphatidylethanolamine binding 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:0008484 sulfuric ester hydrolase activity 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:0016805 dipeptidase activity 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:0019198 transmembrane receptor protein phosphatase activity 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:0030548 acetylcholine receptor regulator activity 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:0046965 nuclear retinoid X receptor binding 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:0070402 NADPH binding 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:1901567 fatty acid derivative binding 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:1990226 histone methyltransferase binding 1/982 17/18639 0.0588235294117647 1.11650892536241 0.601684777367207 0.983609038650794 GO:0000146 microfilament motor activity 2/982 38/18639 0.0526315789473684 0.9989816700611 0.602147018830657 0.983609038650794 GO:0042162 telomeric DNA binding 2/982 38/18639 0.0526315789473684 0.9989816700611 0.602147018830657 0.983609038650794 GO:0042887 amide transmembrane transporter activity 2/982 38/18639 0.0526315789473684 0.9989816700611 0.602147018830657 0.983609038650794 GO:0046332 SMAD binding 4/982 79/18639 0.0506329113924051 0.961045657273969 0.603899417416458 0.983609038650794 GO:0004879 nuclear receptor activity 3/982 59/18639 0.0508474576271186 0.9651178846353 0.607511632778789 0.983609038650794 GO:0070888 E-box binding 3/982 59/18639 0.0508474576271186 0.9651178846353 0.607511632778789 0.983609038650794 GO:0015079 potassium ion transmembrane transporter activity 8/982 160/18639 0.05 0.949032586558045 0.611128494692683 0.983609038650794 GO:0022836 gated channel activity 16/982 318/18639 0.050314465408805 0.95500134496407 0.611778439501879 0.983609038650794 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/982 39/18639 0.0512820512820513 0.973366755444149 0.616399595348543 0.983609038650794 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/982 60/18639 0.05 0.949032586558045 0.618970783635567 0.983609038650794 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/982 60/18639 0.05 0.949032586558045 0.618970783635567 0.983609038650794 GO:0098531 ligand-modulated transcription factor activity 3/982 60/18639 0.05 0.949032586558045 0.618970783635567 0.983609038650794 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0004706 JUN kinase kinase kinase activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0008409 5'-3' exonuclease activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0008525 phosphatidylcholine transporter activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0015172 acidic amino acid transmembrane transporter activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0015280 ligand-gated sodium channel activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0015373 monoatomic anion:sodium symporter activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0022851 GABA-gated chloride ion channel activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0032393 MHC class I receptor activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0070628 proteasome binding 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0099602 neurotransmitter receptor regulator activity 1/982 18/18639 0.0555555555555556 1.05448065173116 0.62268926392211 0.983609038650794 GO:0008528 G protein-coupled peptide receptor activity 6/982 122/18639 0.0491803278688525 0.933474675302995 0.626758941866858 0.983609038650794 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/982 122/18639 0.0491803278688525 0.933474675302995 0.626758941866858 0.983609038650794 GO:0061791 GTPase motor activity 2/982 40/18639 0.05 0.949032586558045 0.630256535828963 0.983609038650794 GO:1990606 membrane scission GTPase motor activity 2/982 40/18639 0.05 0.949032586558045 0.630256535828963 0.983609038650794 GO:0022843 voltage-gated monoatomic cation channel activity 7/982 143/18639 0.048951048951049 0.929122812014869 0.632927751678015 0.983609038650794 GO:0015081 sodium ion transmembrane transporter activity 8/982 164/18639 0.0487804878048781 0.925885450300532 0.63887020860285 0.983609038650794 GO:0005267 potassium channel activity 6/982 124/18639 0.0483870967741935 0.918418632152947 0.642466742016064 0.983609038650794 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0004890 GABA-A receptor activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0015245 fatty acid transmembrane transporter activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0022821 solute:potassium antiporter activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0022840 leak channel activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0022842 narrow pore channel activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0034987 immunoglobulin receptor binding 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0046624 sphingolipid transporter activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0050145 nucleoside monophosphate kinase activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0099589 serotonin receptor activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0120227 acyl-CoA binding 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0140036 ubiquitin-modified protein reader activity 1/982 19/18639 0.0526315789473684 0.9989816700611 0.642587182553145 0.983609038650794 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/982 41/18639 0.0487804878048781 0.925885450300532 0.643719924917956 0.983609038650794 GO:0042169 SH2 domain binding 2/982 41/18639 0.0487804878048781 0.925885450300532 0.643719924917956 0.983609038650794 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/982 41/18639 0.0487804878048781 0.925885450300532 0.643719924917956 0.983609038650794 GO:1901981 phosphatidylinositol phosphate binding 9/982 185/18639 0.0486486486486487 0.923383057191611 0.644588787226823 0.983609038650794 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 24/982 484/18639 0.0495867768595041 0.941189342041036 0.650845222156504 0.983609038650794 GO:0015276 ligand-gated monoatomic ion channel activity 9/982 186/18639 0.0483870967741935 0.918418632152947 0.650924076220568 0.983609038650794 GO:0022824 transmitter-gated monoatomic ion channel activity 3/982 63/18639 0.0476190476190476 0.903840558626709 0.651965079593866 0.983609038650794 GO:0022835 transmitter-gated channel activity 3/982 63/18639 0.0476190476190476 0.903840558626709 0.651965079593866 0.983609038650794 GO:1901682 sulfur compound transmembrane transporter activity 3/982 63/18639 0.0476190476190476 0.903840558626709 0.651965079593866 0.983609038650794 GO:0004527 exonuclease activity 4/982 84/18639 0.0476190476190476 0.903840558626709 0.652217938306582 0.983609038650794 GO:0015293 symporter activity 7/982 146/18639 0.0479452054794521 0.910031247384427 0.654486097249859 0.983609038650794 GO:0004520 DNA endonuclease activity 2/982 42/18639 0.0476190476190476 0.903840558626709 0.656792725148848 0.983609038650794 GO:0035198 miRNA binding 2/982 42/18639 0.0476190476190476 0.903840558626709 0.656792725148848 0.983609038650794 GO:0051879 Hsp90 protein binding 2/982 42/18639 0.0476190476190476 0.903840558626709 0.656792725148848 0.983609038650794 GO:0005326 neurotransmitter transmembrane transporter activity 1/982 20/18639 0.05 0.949032586558045 0.661436773677356 0.983609038650794 GO:0016004 phospholipase activator activity 1/982 20/18639 0.05 0.949032586558045 0.661436773677356 0.983609038650794 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/982 20/18639 0.05 0.949032586558045 0.661436773677356 0.983609038650794 GO:0030627 pre-mRNA 5'-splice site binding 1/982 20/18639 0.05 0.949032586558045 0.661436773677356 0.983609038650794 GO:0030742 GTP-dependent protein binding 1/982 20/18639 0.05 0.949032586558045 0.661436773677356 0.983609038650794 GO:0043024 ribosomal small subunit binding 1/982 20/18639 0.05 0.949032586558045 0.661436773677356 0.983609038650794 GO:0061608 nuclear import signal receptor activity 1/982 20/18639 0.05 0.949032586558045 0.661436773677356 0.983609038650794 GO:0140939 histone H4 methyltransferase activity 1/982 20/18639 0.05 0.949032586558045 0.661436773677356 0.983609038650794 GO:0022834 ligand-gated channel activity 9/982 188/18639 0.0478723404255319 0.908648221172596 0.663400801102671 0.983609038650794 GO:0046943 carboxylic acid transmembrane transporter activity 9/982 188/18639 0.0478723404255319 0.908648221172596 0.663400801102671 0.983609038650794 GO:0004519 endonuclease activity 6/982 127/18639 0.047244094488189 0.896723703834373 0.665269805591784 0.983609038650794 GO:0004518 nuclease activity 10/982 209/18639 0.0478468899521531 0.908165154601 0.667847188940965 0.983609038650794 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/982 43/18639 0.0465116279069767 0.88282101075167 0.669478678836684 0.983609038650794 GO:0005245 voltage-gated calcium channel activity 2/982 43/18639 0.0465116279069767 0.88282101075167 0.669478678836684 0.983609038650794 GO:0008375 acetylglucosaminyltransferase activity 2/982 43/18639 0.0465116279069767 0.88282101075167 0.669478678836684 0.983609038650794 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/982 43/18639 0.0465116279069767 0.88282101075167 0.669478678836684 0.983609038650794 GO:0005342 organic acid transmembrane transporter activity 9/982 189/18639 0.0476190476190476 0.903840558626709 0.669540579570376 0.983609038650794 GO:0030695 GTPase regulator activity 24/982 489/18639 0.049079754601227 0.931565729136731 0.670413657114377 0.983609038650794 GO:0001653 peptide receptor activity 6/982 128/18639 0.046875 0.889718049898167 0.672663791401272 0.983609038650794 GO:0060589 nucleoside-triphosphatase regulator activity 24/982 490/18639 0.0489795918367347 0.929664574587472 0.674258435226604 0.983609038650794 GO:0001216 DNA-binding transcription activator activity 24/982 491/18639 0.0488798370672098 0.927771164048598 0.678079627757948 0.983609038650794 GO:0005496 steroid binding 5/982 108/18639 0.0462962962962963 0.878733876442634 0.678791107136258 0.983609038650794 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/982 21/18639 0.0476190476190476 0.903840558626709 0.67929321539006 0.983609038650794 GO:0005123 death receptor binding 1/982 21/18639 0.0476190476190476 0.903840558626709 0.67929321539006 0.983609038650794 GO:0005248 voltage-gated sodium channel activity 1/982 21/18639 0.0476190476190476 0.903840558626709 0.67929321539006 0.983609038650794 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/982 21/18639 0.0476190476190476 0.903840558626709 0.67929321539006 0.983609038650794 GO:0010314 phosphatidylinositol-5-phosphate binding 1/982 21/18639 0.0476190476190476 0.903840558626709 0.67929321539006 0.983609038650794 GO:0015174 basic amino acid transmembrane transporter activity 1/982 21/18639 0.0476190476190476 0.903840558626709 0.67929321539006 0.983609038650794 GO:0036122 BMP binding 1/982 21/18639 0.0476190476190476 0.903840558626709 0.67929321539006 0.983609038650794 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/982 21/18639 0.0476190476190476 0.903840558626709 0.67929321539006 0.983609038650794 GO:1904047 S-adenosyl-L-methionine binding 1/982 21/18639 0.0476190476190476 0.903840558626709 0.67929321539006 0.983609038650794 GO:0001046 core promoter sequence-specific DNA binding 2/982 44/18639 0.0454545454545455 0.86275689687095 0.681782217855688 0.985845755458918 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/982 130/18639 0.0461538461538462 0.876030079899734 0.687135582772242 0.991100117081802 GO:0140303 intramembrane lipid transporter activity 2/982 45/18639 0.0444444444444444 0.843584521384929 0.693708380742773 0.991100117081802 GO:0005262 calcium channel activity 6/982 131/18639 0.0458015267175573 0.869342827381415 0.694211921047716 0.991100117081802 GO:0005243 gap junction channel activity 1/982 22/18639 0.0454545454545455 0.86275689687095 0.696208784328021 0.991100117081802 GO:0015377 chloride:monoatomic cation symporter activity 1/982 22/18639 0.0454545454545455 0.86275689687095 0.696208784328021 0.991100117081802 GO:0140035 ubiquitin-like protein reader activity 1/982 22/18639 0.0454545454545455 0.86275689687095 0.696208784328021 0.991100117081802 GO:0005543 phospholipid binding 24/982 497/18639 0.0482897384305835 0.916570707339762 0.700498165897191 0.991100117081802 GO:0005548 phospholipid transporter activity 3/982 68/18639 0.0441176470588235 0.837381694021804 0.702301271269474 0.991100117081802 GO:0032934 sterol binding 3/982 68/18639 0.0441176470588235 0.837381694021804 0.702301271269474 0.991100117081802 GO:0030276 clathrin binding 2/982 46/18639 0.0434782608695652 0.825245727441778 0.705262736606823 0.991100117081802 GO:0005506 iron ion binding 7/982 154/18639 0.0454545454545455 0.86275689687095 0.708125702054158 0.991100117081802 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/982 23/18639 0.0434782608695652 0.825245727441778 0.712233008090705 0.991100117081802 GO:0005212 structural constituent of eye lens 1/982 23/18639 0.0434782608695652 0.825245727441778 0.712233008090705 0.991100117081802 GO:0005283 amino acid:sodium symporter activity 1/982 23/18639 0.0434782608695652 0.825245727441778 0.712233008090705 0.991100117081802 GO:0016917 GABA receptor activity 1/982 23/18639 0.0434782608695652 0.825245727441778 0.712233008090705 0.991100117081802 GO:0031681 G-protein beta-subunit binding 1/982 23/18639 0.0434782608695652 0.825245727441778 0.712233008090705 0.991100117081802 GO:0043274 phospholipase binding 1/982 23/18639 0.0434782608695652 0.825245727441778 0.712233008090705 0.991100117081802 GO:0099186 structural constituent of postsynapse 1/982 23/18639 0.0434782608695652 0.825245727441778 0.712233008090705 0.991100117081802 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/982 23/18639 0.0434782608695652 0.825245727441778 0.712233008090705 0.991100117081802 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/982 91/18639 0.043956043956044 0.83431436180927 0.712951234539108 0.991100117081802 GO:0004252 serine-type endopeptidase activity 8/982 176/18639 0.0454545454545455 0.86275689687095 0.714998507643894 0.991100117081802 GO:0001784 phosphotyrosine residue binding 2/982 47/18639 0.0425531914893617 0.807687307708974 0.716451315357896 0.991100117081802 GO:0140359 ABC-type transporter activity 2/982 47/18639 0.0425531914893617 0.807687307708974 0.716451315357896 0.991100117081802 GO:0005261 monoatomic cation channel activity 16/982 341/18639 0.0469208211143695 0.890587764511948 0.719172836299608 0.991100117081802 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/982 70/18639 0.0428571428571429 0.813456502764038 0.720815772434589 0.991100117081802 GO:0052689 carboxylic ester hydrolase activity 4/982 92/18639 0.0434782608695652 0.825245727441778 0.720958896127454 0.991100117081802 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/982 48/18639 0.0416666666666667 0.790860488798371 0.727280543802696 0.991100117081802 GO:0140693 molecular condensate scaffold activity 2/982 48/18639 0.0416666666666667 0.790860488798371 0.727280543802696 0.991100117081802 GO:0005540 hyaluronic acid binding 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0015149 hexose transmembrane transporter activity 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0030552 cAMP binding 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0035035 histone acetyltransferase binding 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0050699 WW domain binding 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0055056 D-glucose transmembrane transporter activity 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0060229 lipase activator activity 1/982 24/18639 0.0416666666666667 0.790860488798371 0.727412809662198 0.991100117081802 GO:0099094 ligand-gated monoatomic cation channel activity 6/982 136/18639 0.0441176470588235 0.837381694021804 0.727978463322378 0.991100117081802 GO:0140299 molecular sensor activity 3/982 71/18639 0.0422535211267606 0.801999368922291 0.729731189902933 0.991100117081802 GO:0035254 glutamate receptor binding 2/982 49/18639 0.0408163265306122 0.774720478822894 0.737757187182855 0.991100117081802 GO:0015294 solute:monoatomic cation symporter activity 5/982 116/18639 0.0431034482758621 0.818131540136246 0.737789570635718 0.991100117081802 GO:0004709 MAP kinase kinase kinase activity 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0005251 delayed rectifier potassium channel activity 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0005537 D-mannose binding 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0008139 nuclear localization sequence binding 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0008483 transaminase activity 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0015645 fatty acid ligase activity 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0042974 nuclear retinoic acid receptor binding 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0047617 fatty acyl-CoA hydrolase activity 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0120515 fatty acid-CoA ligase activity 1/982 25/18639 0.04 0.759226069246436 0.741792644253212 0.991100117081802 GO:0004867 serine-type endopeptidase inhibitor activity 4/982 95/18639 0.0421052631578947 0.79918533604888 0.743985305154297 0.991100117081802 GO:1990782 protein tyrosine kinase binding 5/982 117/18639 0.0427350427350427 0.811138962870124 0.744574405677279 0.991100117081802 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/982 73/18639 0.0410958904109589 0.780026783472366 0.746888461989779 0.991100117081802 GO:0070851 growth factor receptor binding 6/982 139/18639 0.0431654676258993 0.819308707819895 0.746938580208102 0.991100117081802 GO:0005006 epidermal growth factor receptor activity 2/982 50/18639 0.04 0.759226069246436 0.747888295760839 0.991100117081802 GO:0046873 metal ion transmembrane transporter activity 21/982 450/18639 0.0466666666666667 0.885763747454175 0.748279237027449 0.991100117081802 GO:0004713 protein tyrosine kinase activity 6/982 140/18639 0.0428571428571429 0.813456502764038 0.753042082566793 0.991100117081802 GO:0004529 DNA exonuclease activity 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0015145 monosaccharide transmembrane transporter activity 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0016289 acyl-CoA hydrolase activity 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0030507 spectrin binding 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0043548 phosphatidylinositol 3-kinase binding 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0050681 nuclear androgen receptor binding 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0051139 metal cation:proton antiporter activity 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0052742 phosphatidylinositol kinase activity 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0070412 R-SMAD binding 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0120014 phospholipid transfer activity 1/982 26/18639 0.0384615384615385 0.730025066583112 0.755414628960601 0.991100117081802 GO:0005272 sodium channel activity 2/982 51/18639 0.0392156862745098 0.744339283574937 0.757681156084735 0.991100117081802 GO:0016597 amino acid binding 2/982 51/18639 0.0392156862745098 0.744339283574937 0.757681156084735 0.991100117081802 GO:0016830 carbon-carbon lyase activity 2/982 51/18639 0.0392156862745098 0.744339283574937 0.757681156084735 0.991100117081802 GO:0030594 neurotransmitter receptor activity 4/982 97/18639 0.0412371134020619 0.782707287882924 0.75851436163636 0.991100117081802 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/982 52/18639 0.0384615384615385 0.730025066583112 0.767143246588009 0.995191919241145 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/982 27/18639 0.037037037037037 0.702987101154107 0.768318665621037 0.995191919241145 GO:0005385 zinc ion transmembrane transporter activity 1/982 27/18639 0.037037037037037 0.702987101154107 0.768318665621037 0.995191919241145 GO:0008395 steroid hydroxylase activity 1/982 27/18639 0.037037037037037 0.702987101154107 0.768318665621037 0.995191919241145 GO:0015252 proton channel activity 1/982 27/18639 0.037037037037037 0.702987101154107 0.768318665621037 0.995191919241145 GO:0016405 CoA-ligase activity 1/982 27/18639 0.037037037037037 0.702987101154107 0.768318665621037 0.995191919241145 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/982 27/18639 0.037037037037037 0.702987101154107 0.768318665621037 0.995191919241145 GO:0005544 calcium-dependent phospholipid binding 2/982 53/18639 0.0377358490566038 0.716251008723053 0.776282197203439 0.999999999891393 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/982 53/18639 0.0377358490566038 0.716251008723053 0.776282197203439 0.999999999891393 GO:0000287 magnesium ion binding 10/982 230/18639 0.0434782608695652 0.825245727441778 0.776512436102869 0.999999999891393 GO:0016866 intramolecular transferase activity 1/982 28/18639 0.0357142857142857 0.677880418970032 0.780542557215715 0.999999999891393 GO:0046966 nuclear thyroid hormone receptor binding 1/982 28/18639 0.0357142857142857 0.677880418970032 0.780542557215715 0.999999999891393 GO:0051019 mitogen-activated protein kinase binding 1/982 28/18639 0.0357142857142857 0.677880418970032 0.780542557215715 0.999999999891393 GO:0051119 sugar transmembrane transporter activity 1/982 28/18639 0.0357142857142857 0.677880418970032 0.780542557215715 0.999999999891393 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/982 28/18639 0.0357142857142857 0.677880418970032 0.780542557215715 0.999999999891393 GO:0050661 NADP binding 2/982 54/18639 0.037037037037037 0.702987101154107 0.785105752692236 0.999999999891393 GO:0019199 transmembrane receptor protein kinase activity 3/982 78/18639 0.0384615384615385 0.730025066583112 0.785971738406479 0.999999999891393 GO:0008238 exopeptidase activity 4/982 102/18639 0.0392156862745098 0.744339283574937 0.792033248826692 0.999999999891393 GO:0016417 S-acyltransferase activity 1/982 29/18639 0.0344827586206897 0.654505232108996 0.792122118164303 0.999999999891393 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/982 29/18639 0.0344827586206897 0.654505232108996 0.792122118164303 0.999999999891393 GO:0051861 glycolipid binding 1/982 29/18639 0.0344827586206897 0.654505232108996 0.792122118164303 0.999999999891393 GO:0140313 molecular sequestering activity 2/982 55/18639 0.0363636363636364 0.69020551749676 0.793621739409598 0.999999999891393 GO:0000049 tRNA binding 3/982 80/18639 0.0375 0.711774439918534 0.800143597015936 0.999999999891393 GO:0030170 pyridoxal phosphate binding 2/982 56/18639 0.0357142857142857 0.677880418970032 0.801838035247001 0.999999999891393 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/982 56/18639 0.0357142857142857 0.677880418970032 0.801838035247001 0.999999999891393 GO:0170055 lipid transmembrane transporter activity 2/982 56/18639 0.0357142857142857 0.677880418970032 0.801838035247001 0.999999999891393 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/982 30/18639 0.0333333333333333 0.632688391038696 0.803091278828604 0.999999999891393 GO:0070566 adenylyltransferase activity 1/982 30/18639 0.0333333333333333 0.632688391038696 0.803091278828604 0.999999999891393 GO:0098918 structural constituent of synapse 1/982 30/18639 0.0333333333333333 0.632688391038696 0.803091278828604 0.999999999891393 GO:0042826 histone deacetylase binding 5/982 127/18639 0.0393700787401575 0.747269753195311 0.80536956537196 0.999999999891393 GO:0030971 receptor tyrosine kinase binding 3/982 81/18639 0.037037037037037 0.702987101154107 0.806929587438216 0.999999999891393 GO:0008236 serine-type peptidase activity 8/982 194/18639 0.0412371134020619 0.782707287882924 0.807738356634864 0.999999999891393 GO:0070279 vitamin B6 binding 2/982 57/18639 0.0350877192982456 0.665987780040733 0.809762542509303 0.999999999891393 GO:0016878 acid-thiol ligase activity 1/982 31/18639 0.032258064516129 0.612279088101964 0.813482184529626 0.999999999891393 GO:0047499 calcium-independent phospholipase A2 activity 1/982 31/18639 0.032258064516129 0.612279088101964 0.813482184529626 0.999999999891393 GO:0070273 phosphatidylinositol-4-phosphate binding 1/982 31/18639 0.032258064516129 0.612279088101964 0.813482184529626 0.999999999891393 GO:0008408 3'-5' exonuclease activity 2/982 58/18639 0.0344827586206897 0.654505232108996 0.817403163501363 0.999999999891393 GO:0061980 regulatory RNA binding 2/982 58/18639 0.0344827586206897 0.654505232108996 0.817403163501363 0.999999999891393 GO:0047498 calcium-dependent phospholipase A2 activity 1/982 32/18639 0.03125 0.593145366598778 0.823325289365821 0.999999999891393 GO:0051059 NF-kappaB binding 1/982 32/18639 0.03125 0.593145366598778 0.823325289365821 0.999999999891393 GO:0045309 protein phosphorylated amino acid binding 2/982 59/18639 0.0338983050847458 0.6434119230902 0.824767778614436 0.999999999891393 GO:0017171 serine hydrolase activity 8/982 198/18639 0.0404040404040404 0.766895019440844 0.824866247742715 0.999999999891393 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/982 60/18639 0.0333333333333333 0.632688391038696 0.831864226717155 0.999999999891393 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/982 60/18639 0.0333333333333333 0.632688391038696 0.831864226717155 0.999999999891393 GO:0019239 deaminase activity 1/982 33/18639 0.0303030303030303 0.575171264580633 0.832649445105207 0.999999999891393 GO:0071889 14-3-3 protein binding 1/982 33/18639 0.0303030303030303 0.575171264580633 0.832649445105207 0.999999999891393 GO:0140311 protein sequestering activity 1/982 33/18639 0.0303030303030303 0.575171264580633 0.832649445105207 0.999999999891393 GO:0005319 lipid transporter activity 7/982 178/18639 0.0393258426966292 0.746430124259136 0.834047909679735 0.999999999891393 GO:0003924 GTPase activity 14/982 331/18639 0.0422960725075529 0.80280702186179 0.835939778644064 0.999999999891393 GO:0004222 metalloendopeptidase activity 4/982 110/18639 0.0363636363636364 0.69020551749676 0.83778321851682 0.999999999891393 GO:0008376 acetylgalactosaminyltransferase activity 1/982 34/18639 0.0294117647058824 0.558254462681203 0.841481985409769 0.999999999891393 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/982 34/18639 0.0294117647058824 0.558254462681203 0.841481985409769 0.999999999891393 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/982 34/18639 0.0294117647058824 0.558254462681203 0.841481985409769 0.999999999891393 GO:0016831 carboxy-lyase activity 1/982 34/18639 0.0294117647058824 0.558254462681203 0.841481985409769 0.999999999891393 GO:0042393 histone binding 10/982 247/18639 0.0404858299595142 0.768447438508538 0.843898264399893 0.999999999891393 GO:0015179 L-amino acid transmembrane transporter activity 2/982 62/18639 0.032258064516129 0.612279088101964 0.845283666790868 0.999999999891393 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/982 181/18639 0.0386740331491713 0.734058354243792 0.846227573941374 0.999999999891393 GO:0016779 nucleotidyltransferase activity 5/982 136/18639 0.0367647058823529 0.697818078351504 0.849724308297178 0.999999999891393 GO:0000175 3'-5'-RNA exonuclease activity 1/982 35/18639 0.0285714285714286 0.542304335176025 0.849848805636999 0.999999999891393 GO:0004623 phospholipase A2 activity 1/982 35/18639 0.0285714285714286 0.542304335176025 0.849848805636999 0.999999999891393 GO:0005154 epidermal growth factor receptor binding 1/982 35/18639 0.0285714285714286 0.542304335176025 0.849848805636999 0.999999999891393 GO:0005343 organic acid:sodium symporter activity 1/982 35/18639 0.0285714285714286 0.542304335176025 0.849848805636999 0.999999999891393 GO:0140104 molecular carrier activity 10/982 249/18639 0.0401606425702811 0.76227516992614 0.85066420274834 0.999999999891393 GO:0005096 GTPase activator activity 11/982 271/18639 0.040590405904059 0.770432358091402 0.850914877416729 0.999999999891393 GO:0016791 phosphatase activity 11/982 273/18639 0.0402930402930403 0.764788164991831 0.857192520787123 0.999999999891393 GO:0008237 metallopeptidase activity 7/982 184/18639 0.0380434782608696 0.722090011511556 0.857678909163365 0.999999999891393 GO:0005484 SNAP receptor activity 1/982 36/18639 0.0277777777777778 0.52724032586558 0.857774438450613 0.999999999891393 GO:0045505 dynein intermediate chain binding 1/982 36/18639 0.0277777777777778 0.52724032586558 0.857774438450613 0.999999999891393 GO:0035401 histone H3Y41 kinase activity 4/982 115/18639 0.0347826086956522 0.660196581953422 0.86186100372559 0.999999999891393 GO:0140801 histone H2AXY142 kinase activity 4/982 115/18639 0.0347826086956522 0.660196581953422 0.86186100372559 0.999999999891393 GO:0120013 lipid transfer activity 2/982 65/18639 0.0307692307692308 0.584020053266489 0.863593371244681 0.999999999891393 GO:0072341 modified amino acid binding 3/982 91/18639 0.032967032967033 0.625735771356953 0.864663294948349 0.999999999891393 GO:0030280 structural constituent of skin epidermis 1/982 37/18639 0.027027027027027 0.512990587328673 0.865282125460315 0.999999999891393 GO:0030551 cyclic nucleotide binding 1/982 37/18639 0.027027027027027 0.512990587328673 0.865282125460315 0.999999999891393 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/982 38/18639 0.0263157894736842 0.49949083503055 0.872393885098955 0.999999999891393 GO:0030145 manganese ion binding 2/982 68/18639 0.0294117647058824 0.558254462681203 0.879896598561082 0.999999999891393 GO:0098960 postsynaptic neurotransmitter receptor activity 2/982 69/18639 0.0289855072463768 0.550163818294519 0.884918196836015 0.999999999891393 GO:0008194 UDP-glycosyltransferase activity 5/982 145/18639 0.0344827586206897 0.654505232108996 0.885354734478779 0.999999999891393 GO:0004177 aminopeptidase activity 1/982 40/18639 0.025 0.474516293279022 0.885511962603864 0.999999999891393 GO:0004532 RNA exonuclease activity 1/982 40/18639 0.025 0.474516293279022 0.885511962603864 0.999999999891393 GO:0015144 carbohydrate transmembrane transporter activity 1/982 40/18639 0.025 0.474516293279022 0.885511962603864 0.999999999891393 GO:0003730 mRNA 3'-UTR binding 10/982 262/18639 0.0381679389312977 0.724452356151179 0.889168305751852 0.999999999891393 GO:0016278 lysine N-methyltransferase activity 2/982 70/18639 0.0285714285714286 0.542304335176025 0.889744738730175 0.999999999891393 GO:0001727 lipid kinase activity 1/982 41/18639 0.024390243902439 0.462942725150266 0.891556763546012 0.999999999891393 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/982 41/18639 0.024390243902439 0.462942725150266 0.891556763546012 0.999999999891393 GO:0008170 N-methyltransferase activity 3/982 98/18639 0.0306122448979592 0.58104035911717 0.895474089008952 0.999999999891393 GO:0004402 histone acetyltransferase activity 1/982 42/18639 0.0238095238095238 0.451920279313355 0.89728271570204 0.999999999891393 GO:0042379 chemokine receptor binding 2/982 72/18639 0.0277777777777778 0.52724032586558 0.898838854863423 0.999999999891393 GO:0016758 hexosyltransferase activity 7/982 197/18639 0.0355329949238579 0.674439401614854 0.899524119964524 0.999999999891393 GO:0016757 glycosyltransferase activity 10/982 267/18639 0.0374531835205993 0.710885832627749 0.901624401090674 0.999999999891393 GO:0043130 ubiquitin binding 3/982 100/18639 0.03 0.569419551934827 0.903038445969649 0.999999999891393 GO:0004521 RNA endonuclease activity 2/982 73/18639 0.0273972602739726 0.520017855648244 0.903119147620427 0.999999999891393 GO:0001223 transcription coactivator binding 1/982 44/18639 0.0227272727272727 0.431378448435475 0.907844398166948 0.999999999891393 GO:0043014 alpha-tubulin binding 1/982 44/18639 0.0227272727272727 0.431378448435475 0.907844398166948 0.999999999891393 GO:0003774 cytoskeletal motor activity 5/982 153/18639 0.0326797385620915 0.620282736312448 0.910693699616107 0.999999999891393 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/982 45/18639 0.0222222222222222 0.421792260692464 0.912711125835679 0.999999999891393 GO:0008009 chemokine activity 1/982 45/18639 0.0222222222222222 0.421792260692464 0.912711125835679 0.999999999891393 GO:0046915 transition metal ion transmembrane transporter activity 1/982 45/18639 0.0222222222222222 0.421792260692464 0.912711125835679 0.999999999891393 GO:0035591 signaling adaptor activity 4/982 129/18639 0.0310077519379845 0.588547340501113 0.913625590855236 0.999999999891393 GO:0004180 carboxypeptidase activity 1/982 46/18639 0.0217391304347826 0.412622863720889 0.917321090040764 0.999999999891393 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/982 46/18639 0.0217391304347826 0.412622863720889 0.917321090040764 0.999999999891393 GO:0043495 protein-membrane adaptor activity 1/982 47/18639 0.0212765957446809 0.403843653854487 0.921687824273001 0.999999999891393 GO:0061733 protein-lysine-acetyltransferase activity 1/982 47/18639 0.0212765957446809 0.403843653854487 0.921687824273001 0.999999999891393 GO:0140938 histone H3 methyltransferase activity 1/982 47/18639 0.0212765957446809 0.403843653854487 0.921687824273001 0.999999999891393 GO:0000149 SNARE binding 3/982 106/18639 0.0283018867924528 0.53718825654229 0.922852600705994 0.999999999891393 GO:0015370 solute:sodium symporter activity 2/982 79/18639 0.0253164556962025 0.480522828636985 0.925442236139312 0.999999999891393 GO:0008188 neuropeptide receptor activity 1/982 48/18639 0.0208333333333333 0.395430244399185 0.92582414938939 0.999999999891393 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/982 48/18639 0.0208333333333333 0.395430244399185 0.92582414938939 0.999999999891393 GO:0032266 phosphatidylinositol-3-phosphate binding 1/982 48/18639 0.0208333333333333 0.395430244399185 0.92582414938939 0.999999999891393 GO:0038187 pattern recognition receptor activity 1/982 48/18639 0.0208333333333333 0.395430244399185 0.92582414938939 0.999999999891393 GO:0005004 GPI-linked ephrin receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0005008 hepatocyte growth factor receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0005009 insulin receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0005011 macrophage colony-stimulating factor receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0005020 stem cell factor receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0008288 boss receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0036332 placental growth factor receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0038062 protein tyrosine kinase collagen receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0060175 brain-derived neurotrophic factor receptor activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0060590 ATPase regulator activity 1/982 49/18639 0.0204081632653061 0.387360239411447 0.929742211102026 0.999999999891393 GO:0005125 cytokine activity 8/982 234/18639 0.0341880341880342 0.648911170296099 0.930484693721906 0.999999999891393 GO:0015101 organic cation transmembrane transporter activity 2/982 81/18639 0.0246913580246914 0.468658067436071 0.931736678322914 0.999999999891393 GO:0033192 calmodulin-dependent protein phosphatase activity 2/982 81/18639 0.0246913580246914 0.468658067436071 0.931736678322914 0.999999999891393 GO:0140791 histone H2AXS140 phosphatase activity 2/982 81/18639 0.0246913580246914 0.468658067436071 0.931736678322914 0.999999999891393 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/982 81/18639 0.0246913580246914 0.468658067436071 0.931736678322914 0.999999999891393 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/982 81/18639 0.0246913580246914 0.468658067436071 0.931736678322914 0.999999999891393 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/982 81/18639 0.0246913580246914 0.468658067436071 0.931736678322914 0.999999999891393 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/982 81/18639 0.0246913580246914 0.468658067436071 0.931736678322914 0.999999999891393 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/982 81/18639 0.0246913580246914 0.468658067436071 0.931736678322914 0.999999999891393 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/982 81/18639 0.0246913580246914 0.468658067436071 0.931736678322914 0.999999999891393 GO:0005007 fibroblast growth factor receptor activity 1/982 50/18639 0.02 0.379613034623218 0.933453515496744 0.999999999891393 GO:0005017 platelet-derived growth factor receptor activity 1/982 50/18639 0.02 0.379613034623218 0.933453515496744 0.999999999891393 GO:0005019 platelet-derived growth factor beta-receptor activity 1/982 50/18639 0.02 0.379613034623218 0.933453515496744 0.999999999891393 GO:0048020 CCR chemokine receptor binding 1/982 50/18639 0.02 0.379613034623218 0.933453515496744 0.999999999891393 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/982 82/18639 0.024390243902439 0.462942725150266 0.934692087100222 0.999999999891393 GO:0033549 MAP kinase phosphatase activity 2/982 82/18639 0.024390243902439 0.462942725150266 0.934692087100222 0.999999999891393 GO:0035091 phosphatidylinositol binding 10/982 284/18639 0.0352112676056338 0.668332807435243 0.935562034340741 0.999999999891393 GO:0005010 insulin-like growth factor receptor activity 1/982 51/18639 0.0196078431372549 0.372169641787469 0.936968962684985 0.999999999891393 GO:0005021 vascular endothelial growth factor receptor activity 1/982 51/18639 0.0196078431372549 0.372169641787469 0.936968962684985 0.999999999891393 GO:0005030 neurotrophin receptor activity 1/982 51/18639 0.0196078431372549 0.372169641787469 0.936968962684985 0.999999999891393 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/982 83/18639 0.0240963855421687 0.457365101955684 0.937525979635837 0.999999999891393 GO:0140101 catalytic activity, acting on a tRNA 4/982 139/18639 0.0287769784172662 0.546205805213263 0.93920568187507 0.999999999891393 GO:0017018 myosin phosphatase activity 2/982 84/18639 0.0238095238095238 0.451920279313355 0.940242939965608 0.999999999891393 GO:0005003 ephrin receptor activity 1/982 53/18639 0.0188679245283019 0.358125504361526 0.943453045638491 0.999999999891393 GO:0005005 transmembrane-ephrin receptor activity 1/982 53/18639 0.0188679245283019 0.358125504361526 0.943453045638491 0.999999999891393 GO:0017046 peptide hormone binding 1/982 53/18639 0.0188679245283019 0.358125504361526 0.943453045638491 0.999999999891393 GO:0034212 protein N-acetyltransferase activity 1/982 53/18639 0.0188679245283019 0.358125504361526 0.943453045638491 0.999999999891393 GO:0038064 collagen receptor activity 1/982 53/18639 0.0188679245283019 0.358125504361526 0.943453045638491 0.999999999891393 GO:0008374 O-acyltransferase activity 1/982 55/18639 0.0181818181818182 0.34510275874838 0.949270711725904 0.999999999891393 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/982 89/18639 0.0224719101123595 0.426531499576649 0.952224187907397 0.999999999891393 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/982 89/18639 0.0224719101123595 0.426531499576649 0.952224187907397 0.999999999891393 GO:0140793 histone H2AXY142 phosphatase activity 2/982 90/18639 0.0222222222222222 0.421792260692464 0.954327878576853 0.999999999891393 GO:0003823 antigen binding 5/982 174/18639 0.028735632183908 0.545421026757497 0.955300073302489 0.999999999891393 GO:0032182 ubiquitin-like protein binding 3/982 120/18639 0.025 0.474516293279022 0.955505601182704 0.999999999891393 GO:0004721 phosphoprotein phosphatase activity 5/982 175/18639 0.0285714285714286 0.542304335176025 0.956800987126695 0.999999999891393 GO:0004540 RNA nuclease activity 3/982 121/18639 0.0247933884297521 0.470594671020518 0.957255956220707 0.999999999891393 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/982 122/18639 0.0245901639344262 0.466737337651497 0.958941636888618 0.999999999891393 GO:0001786 phosphatidylserine binding 1/982 59/18639 0.0169491525423729 0.3217059615451 0.959173492935058 0.999999999891393 GO:0031593 polyubiquitin modification-dependent protein binding 1/982 59/18639 0.0169491525423729 0.3217059615451 0.959173492935058 0.999999999891393 GO:0051219 phosphoprotein binding 2/982 93/18639 0.021505376344086 0.408186058734643 0.960120293814186 0.999999999891393 GO:0016410 N-acyltransferase activity 2/982 94/18639 0.0212765957446809 0.403843653854487 0.961889478421209 0.999999999891393 GO:0019905 syntaxin binding 1/982 61/18639 0.0163934426229508 0.311158225100998 0.963375126932221 0.999999999891393 GO:0008276 protein methyltransferase activity 2/982 95/18639 0.0210526315789474 0.39959266802444 0.963583189676599 0.999999999891393 GO:0004896 cytokine receptor activity 2/982 96/18639 0.0208333333333333 0.395430244399185 0.965204458887102 0.999999999891393 GO:0016407 acetyltransferase activity 2/982 96/18639 0.0208333333333333 0.395430244399185 0.965204458887102 0.999999999891393 GO:0004386 helicase activity 4/982 155/18639 0.0258064516129032 0.489823270481571 0.966144110602356 0.999999999891393 GO:0004725 protein tyrosine phosphatase activity 2/982 98/18639 0.0204081632653061 0.387360239411447 0.968241252000068 0.999999999891393 GO:0008235 metalloexopeptidase activity 1/982 66/18639 0.0151515151515152 0.287585632290317 0.972084972906949 0.999999999891393 GO:0016741 transferase activity, transferring one-carbon groups 6/982 215/18639 0.027906976744186 0.529692606451002 0.972918997644955 0.999999999891393 GO:0016500 protein-hormone receptor activity 1/982 67/18639 0.0149253731343284 0.283293309420312 0.973560908760359 0.999999999891393 GO:0042054 histone methyltransferase activity 1/982 67/18639 0.0149253731343284 0.283293309420312 0.973560908760359 0.999999999891393 GO:0004722 protein serine/threonine phosphatase activity 2/982 103/18639 0.0194174757281553 0.368556344294386 0.974757378529373 0.999999999891393 GO:0002039 p53 binding 1/982 69/18639 0.0144927536231884 0.275081909147259 0.976283011285091 0.999999999891393 GO:0008080 N-acetyltransferase activity 1/982 69/18639 0.0144927536231884 0.275081909147259 0.976283011285091 0.999999999891393 GO:0016279 protein-lysine N-methyltransferase activity 1/982 69/18639 0.0144927536231884 0.275081909147259 0.976283011285091 0.999999999891393 GO:0140789 histone phosphatase activity 3/982 136/18639 0.0220588235294118 0.418690847010902 0.976856626940637 0.999999999891393 GO:0004497 monooxygenase activity 2/982 106/18639 0.0188679245283019 0.358125504361526 0.978025384716554 0.999999999891393 GO:0008013 beta-catenin binding 2/982 106/18639 0.0188679245283019 0.358125504361526 0.978025384716554 0.999999999891393 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/982 167/18639 0.0239520958083832 0.454626388770321 0.978532644320459 0.999999999891393 GO:0016874 ligase activity 4/982 167/18639 0.0239520958083832 0.454626388770321 0.978532644320459 0.999999999891393 GO:0140767 enzyme-substrate adaptor activity 3/982 139/18639 0.0215827338129496 0.409654353909947 0.979578046838484 0.999999999891393 GO:0035064 methylated histone binding 1/982 74/18639 0.0135135135135135 0.256495293664336 0.981925376769928 0.999999999891393 GO:0003725 double-stranded RNA binding 1/982 75/18639 0.0133333333333333 0.253075356415479 0.982881438176441 0.999999999891393 GO:0140034 methylation-dependent protein binding 1/982 76/18639 0.0131578947368421 0.249745417515275 0.98378697726881 0.999999999891393 GO:0015631 tubulin binding 12/982 385/18639 0.0311688311688312 0.591604729282937 0.984471732493129 0.999999999891393 GO:0008168 methyltransferase activity 5/982 204/18639 0.0245098039215686 0.465212052234336 0.984595631777682 0.999999999891393 GO:0140097 catalytic activity, acting on DNA 10/982 336/18639 0.0297619047619048 0.564900349141693 0.984805327903582 0.999999999891393 GO:0016887 ATP hydrolysis activity 13/982 417/18639 0.0311750599520384 0.591722955647702 0.987367380795045 0.999999999891393 GO:0000510 H3-H4 histone complex chaperone activity 3/982 151/18639 0.0198675496688742 0.377099041016442 0.987705615025817 0.999999999891393 GO:0140584 chromatin extrusion motor activity 3/982 151/18639 0.0198675496688742 0.377099041016442 0.987705615025817 0.999999999891393 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/982 151/18639 0.0198675496688742 0.377099041016442 0.987705615025817 0.999999999891393 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/982 151/18639 0.0198675496688742 0.377099041016442 0.987705615025817 0.999999999891393 GO:0015616 DNA translocase activity 3/982 152/18639 0.0197368421052632 0.374618126272912 0.988220357414128 0.999999999891393 GO:0140674 ATP-dependent histone chaperone activity 3/982 152/18639 0.0197368421052632 0.374618126272912 0.988220357414128 0.999999999891393 GO:0061775 cohesin loader activity 3/982 153/18639 0.0196078431372549 0.372169641787469 0.988714340818557 0.999999999891393 GO:0140375 immune receptor activity 3/982 156/18639 0.0192307692307692 0.365012533291556 0.990079542113658 0.999999999891393 GO:0050660 flavin adenine dinucleotide binding 1/982 86/18639 0.0116279069767442 0.220705252687917 0.990586323749306 0.999999999891393 GO:0140597 protein carrier chaperone 4/982 188/18639 0.0212765957446809 0.403843653854487 0.990604050265248 0.999999999891393 GO:0140658 ATP-dependent chromatin remodeler activity 3/982 158/18639 0.0189873417721519 0.360392121477739 0.990899714350733 0.999999999891393 GO:0008017 microtubule binding 7/982 276/18639 0.0253623188405797 0.481393341007704 0.991560753055251 0.999999999891393 GO:0003689 DNA clamp loader activity 3/982 160/18639 0.01875 0.355887219959267 0.991654277258542 0.999999999891393 GO:0140713 histone chaperone activity 3/982 164/18639 0.0182926829268293 0.347207043862699 0.992986285954992 0.999999999891393 GO:0140030 modification-dependent protein binding 3/982 173/18639 0.0173410404624277 0.32914424967331 0.99527403589111 0.999999999891393 GO:0008094 ATP-dependent activity, acting on DNA 4/982 210/18639 0.019047619047619 0.361536223450684 0.996176391496751 0.999999999891393 GO:0004843 cysteine-type deubiquitinase activity 1/982 108/18639 0.00925925925925926 0.175746775288527 0.997156402210708 0.999999999891393 GO:0101005 deubiquitinase activity 1/982 115/18639 0.00869565217391304 0.165049145488356 0.998057704756103 0.999999999891393 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/982 229/18639 0.0174672489082969 0.331539768229885 0.998281323709425 0.999999999891393 GO:0004674 protein serine/threonine kinase activity 11/982 433/18639 0.0254041570438799 0.482187457373602 0.998365673834763 0.999999999891393 GO:0140996 histone H3 kinase activity 8/982 357/18639 0.0224089635854342 0.425336733471393 0.998717095588801 0.999999999891393 GO:0016755 aminoacyltransferase activity 13/982 496/18639 0.0262096774193548 0.497476759082846 0.998804736463826 0.999999999891393 GO:0035173 histone kinase activity 8/982 360/18639 0.0222222222222222 0.421792260692464 0.998849861413784 0.999999999891393 GO:0106310 protein serine kinase activity 8/982 361/18639 0.0221606648199446 0.420623861078358 0.998891101078984 0.999999999891393 GO:0019783 ubiquitin-like protein peptidase activity 1/982 127/18639 0.0078740157480315 0.149453950639062 0.998989908769766 0.999999999891393 GO:0035402 histone H3T11 kinase activity 4/982 247/18639 0.0161943319838057 0.307378975403415 0.999207852196535 0.999999999891393 GO:0035403 histone H3T6 kinase activity 4/982 247/18639 0.0161943319838057 0.307378975403415 0.999207852196535 0.999999999891393 GO:0141003 histone H2AX kinase activity 7/982 354/18639 0.019774011299435 0.375323621802617 0.999523639907385 0.999999999891393 GO:0140098 catalytic activity, acting on RNA 8/982 387/18639 0.020671834625323 0.392364893667409 0.999578029661587 0.999999999891393 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/982 243/18639 0.0123456790123457 0.234329033718036 0.999807926862864 0.999999999891393 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0004711 ribosomal protein S6 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0035175 histone H3S10 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0035979 histone H2AXS139 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0044022 histone H3S28 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0044023 histone H4S1 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0044024 histone H2AS1 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0044025 histone H2BS14 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0072354 histone H3T3 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0072371 histone H2AS121 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0140823 histone H2BS36 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0140855 histone H3S57 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0140995 histone H2A kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0140997 histone H4 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0140998 histone H2B kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:1990244 histone H2AT120 kinase activity 3/982 245/18639 0.0122448979591837 0.232416143646868 0.999825206455657 0.999999999891393 GO:0004677 DNA-dependent protein kinase activity 3/982 246/18639 0.0121951219512195 0.231471362575133 0.999833262187351 0.999999999891393 GO:0140857 histone H3T45 kinase activity 3/982 246/18639 0.0121951219512195 0.231471362575133 0.999833262187351 0.999999999891393 GO:0004679 AMP-activated protein kinase activity 3/982 248/18639 0.0120967741935484 0.229604658038237 0.999848291243665 0.999999999891393 GO:0045182 translation regulator activity 6/982 356/18639 0.0168539325842697 0.319898624682487 0.999874831988431 0.999999999891393 GO:0019787 ubiquitin-like protein transferase activity 10/982 479/18639 0.0208768267223382 0.396255777268495 0.999878375910548 0.999999999891393 GO:0061630 ubiquitin protein ligase activity 5/982 353/18639 0.0141643059490085 0.268847758231741 0.999966170963824 0.999999999891393 GO:0061659 ubiquitin-like protein ligase activity 5/982 372/18639 0.0134408602150538 0.255116286709152 0.999985481462444 0.999999999891393 GO:0004842 ubiquitin-protein transferase activity 7/982 449/18639 0.0155902004454343 0.295912165073778 0.999990048347949 0.999999999891393 GO:0004984 olfactory receptor activity 1/982 419/18639 0.00238663484486874 0.0452998847999067 0.999999999891393 0.999999999891393