category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 5/9 180/9376 28.9382716049383 HLA-DPB1/HLA-DPA1/B2M/HLA-B/CCL5 11.7312135111162 Organismal Systems Immune system hsa04612 Antigen processing and presentation 4/9 82/9376 50.8184281842818 HLA-DPB1/HLA-DPA1/B2M/HLA-B 14.0443694663881 Human Diseases Immune disease hsa05330 Allograft rejection 3/9 39/9376 80.1367521367521 HLA-DPB1/HLA-DPA1/HLA-B 15.3501802395731 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 3/9 44/9376 71.030303030303 HLA-DPB1/HLA-DPA1/HLA-B 14.4321691925082 Human Diseases Immune disease hsa05332 Graft-versus-host disease 3/9 45/9376 69.4518518518518 HLA-DPB1/HLA-DPA1/HLA-B 14.2670438720617 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 3/9 54/9376 57.8765432098765 HLA-DPB1/HLA-DPA1/HLA-B 12.9921838269638 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 4/9 205/9376 20.3273712737127 HLA-DPB1/HLA-DPA1/B2M/HLA-B 8.67257383655119 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 3/9 70/9376 44.647619047619 HLA-DPB1/HLA-DPA1/HLA-B 11.3614742074601 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 4/9 224/9376 18.6031746031746 HLA-DPB1/HLA-DPA1/B2M/HLA-B 8.26539537636392 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 3/9 95/9376 32.8982456140351 HLA-DPB1/HLA-DPA1/CCL5 9.6858524044772 Cellular Processes Transport and catabolism hsa04145 Phagosome 3/9 155/9376 20.1634408602151 HLA-DPB1/HLA-DPA1/HLA-B 7.45687669308619 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 3/9 160/9376 19.5333333333333 HLA-DPB1/HLA-DPA1/HLA-B 7.32907098373625 Human Diseases Immune disease hsa05310 Asthma 2/9 32/9376 65.1111111111111 HLA-DPB1/HLA-DPA1 11.2602623926871 Human Diseases Infectious disease: viral hsa05164 Influenza A 3/9 173/9376 18.0655105973025 HLA-DPB1/HLA-DPA1/CCL5 7.02237892583853 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 2/9 50/9376 41.6711111111111 HLA-DPB1/HLA-DPA1 8.93778630134292 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 3/9 227/9376 13.7679882525698 B2M/HLA-B/CCL5 6.03608326488283 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 2/9 66/9376 31.5690235690236 HLA-DPB1/HLA-DPA1 7.72476589854818 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/9 78/9376 26.7122507122507 HLA-DPB1/HLA-DPA1 7.06804421033794 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 2/9 93/9376 22.4038231780167 HLA-DPB1/HLA-DPA1 6.42976775490632 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 2/9 99/9376 21.0460157126824 HLA-DPB1/HLA-DPA1 6.2151056881825 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 2/9 100/9376 20.8355555555556 HLA-DPB1/HLA-DPA1 6.18116919505675 Organismal Systems Immune system hsa04659 Th17 cell differentiation 2/9 109/9376 19.1151885830785 HLA-DPB1/HLA-DPA1 5.8964844797031 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 2/9 112/9376 18.6031746031746 HLA-DPB1/HLA-DPA1 5.8090801367095 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 2/9 143/9376 14.5703185703186 HLA-DPB1/HLA-DPA1 5.06866136095726 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 2/9 181/9376 11.5113566605279 HLA-DPB1/HLA-DPA1 4.42617749658054 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 2/9 214/9376 9.73624091381101 B2M/HLA-B 4.00721807436349 Genetic Information Processing Translation hsa03010 Ribosome 2/9 222/9376 9.38538538538539 RPL27A/RPS26 3.91922948023617 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 2/9 238/9376 8.75443510737628 RPL27A/RPS26 3.75594911973047 Genetic Information Processing Transcription hsa03020 RNA polymerase 1/9 34/9376 30.640522875817 POLR2J3 5.36675809985215 Metabolism Lipid metabolism hsa00590 Arachidonic acid metabolism 1/9 63/9376 16.5361552028219 PTGDS 3.83509085598688 Genetic Information Processing Replication and repair hsa03420 Nucleotide excision repair 1/9 63/9376 16.5361552028219 POLR2J3 3.83509085598688 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/9 71/9376 14.6729264475743 CCL5 3.58458675697259 Organismal Systems Immune system hsa04623 Cytosolic DNA-sensing pathway 1/9 83/9376 12.5515394912985 CCL5 3.27648042454552 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/9 100/9376 10.4177777777778 CCL5 2.93477426043586 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/9 103/9376 10.1143473570658 CCL5 2.88297377095514 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/9 109/9376 9.55759429153925 CCL5 2.7854924994152 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/9 119/9376 8.75443510737628 CCL5 2.63873117238607 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/9 133/9376 7.83291562238931 HLA-B 2.45998259603897 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/9 157/9376 6.63552724699221 HLA-B 2.20723770020222 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/9 187/9376 5.57100415923945 CCL5 1.95706354289177 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/9 193/9376 5.39781232009211 CCL5 1.91350537607223 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/9 196/9376 5.31519274376417 HLA-B 1.8924025592178 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 1/9 205/9376 5.08184281842818 HLA-B 1.831603622173 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/9 216/9376 4.82304526748971 CCL5 1.76195662088715 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/9 250/9376 4.16711111111111 HLA-B 1.57325711616049 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/9 253/9376 4.11769872639438 CCL5 1.55823229673302 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/9 275/9376 3.78828282828283 CCL5 1.45467256003157 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/9 298/9376 3.49589858314691 CCL5 1.35720862262987 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/9 308/9376 3.38239538239538 POLR2J3 1.31777138874906 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/9 333/9376 3.12846179512846 HLA-B 1.22585285635904