category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	5/28	88/9376	19.025974025974	C1QA/C1QB/A2M/C1QC/F13A1	9.29788725473897
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/28	238/9376	7.03481392557023	C1QA/NRP1/C1QB/C1QC/F13A1	5.1609789473475
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	5/28	250/9376	6.69714285714286	DAB2/IL2RA/FOLR2/SNX6/AP2A2	4.99680249518583
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/28	78/9376	12.8791208791209	C1QA/C1QB/C1QC	5.76556847027605
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/28	99/9376	10.1471861471861	C1QA/C1QB/C1QC	5.00733489270103
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/28	103/9376	9.75312066574203	C1QA/C1QB/C1QC	4.88851216127316
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	2/28	30/9376	22.3238095238095	FOLR2/ABCC5	6.40203192539385
NA	NA	hsa04981	Folate transport and metabolism	2/28	31/9376	21.6036866359447	FOLR2/ABCC5	6.28841843342506
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	4/28	275/9376	4.87064935064935	MT-ND1/C1QA/C1QB/C1QC	3.56542184712089
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	3/28	143/9376	7.02497502497503	C1QA/C1QB/C1QC	3.97335303351788
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/28	144/9376	6.97619047619048	C1QA/C1QB/C1QC	3.955151114421
NA	NA	hsa04518	Integrin signaling	3/28	154/9376	6.52319109461967	IGF1/COL1A1/COL1A2	3.78218852745791
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/28	157/9376	6.39854413102821	C1QA/C1QB/C1QC	3.73327409392137
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	4/28	362/9376	3.70007892659826	IGF1/IL2RA/COL1A1/COL1A2	2.86732730026434
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/28	203/9376	4.94862772695285	IGF1/COL1A1/COL1A2	3.11274694093737
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/28	204/9376	4.92436974789916	IGF1/COL1A1/COL1A2	3.10140356574428
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	3/28	205/9376	4.90034843205575	MT-ND1/COL1A1/COL1A2	3.09013385167271
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/28	89/9376	7.52487961476726	COL1A1/COL1A2	3.38481616051684
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/28	93/9376	7.20122887864823	MAF/IL2RA	3.28912487251697
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/28	101/9376	6.63083451202263	COL1A1/COL1A2	3.11373604068474
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/28	103/9376	6.50208044382802	COL1A1/COL1A2	3.07284546724301
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/28	103/9376	6.50208044382802	COL1A1/COL1A2	3.07284546724301
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	3/28	250/9376	4.01828571428571	HEXA/LGMN/AP2A2	2.64725283646656
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/28	106/9376	6.31805929919137	IGF1/FOLR2	3.0135024105835
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/28	15/9376	22.3238095238095	HEXA	4.52329178130363
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/28	16/9376	20.9285714285714	HEXA	4.366199107849
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	1/28	18/9376	18.6031746031746	HEXA	4.09110881355463
Organismal Systems	Immune system	hsa04611	Platelet activation	2/28	126/9376	5.31519274376417	COL1A1/COL1A2	2.66882383133494
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/28	19/9376	17.6240601503759	HEXA	3.96963786342852
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/28	130/9376	5.15164835164835	COL1A1/COL1A2	2.60867871628675
NA	NA	hsa04517	IgSF CAM signaling	3/28	299/9376	3.35977066411849	EPB41L2/NRP1/MTSS1	2.26954880451046
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/28	38/9376	8.81203007518797	HEXA	2.64079124865659
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/28	38/9376	8.81203007518797	IGF1	2.64079124865659
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/28	42/9376	7.97278911564626	SLC40A1	2.47857793735949
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/28	201/9376	3.3319118692253	IGF1/MAF	1.82899461668235
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/28	44/9376	7.61038961038961	HEXA	2.40531152588794
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/28	45/9376	7.44126984126984	ABCC5	2.37038536678053
NA	NA	hsa04081	Hormone signaling	2/28	219/9376	3.05805609915199	IGF1/SLC40A1	1.68658394191907
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/28	51/9376	6.56582633053221	PLD3	2.18120066196397
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/28	224/9376	2.98979591836735	IL2RA/NRP1	1.64960453213027
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/28	52/9376	6.43956043956044	IGF1	2.15263128631854
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/28	53/9376	6.31805929919137	AP2A2	2.12480250815885
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/28	55/9376	6.08831168831169	HEXA	2.07123367894842
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/28	233/9376	2.87431023911711	COL1A1/COL1A2	1.58555160038497
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/28	60/9376	5.58095238095238	IGF1	1.94814807897987
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/28	61/9376	5.48946135831382	SLC40A1	1.92518747587651
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/28	62/9376	5.40092165898618	IGF1	1.90272781825762
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/28	63/9376	5.31519274376417	LTC4S	1.88074958248028
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/28	66/9376	5.07359307359307	MAF	1.8175236589027
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/28	73/9376	4.58708414872798	IGF1	1.68382435311362
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/28	75/9376	4.4647619047619	IGF1	1.64871089244615
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/28	76/9376	4.40601503759398	IGF1	1.63161310514547
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/28	79/9376	4.23869801084991	AP2A2	1.58204155474363
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/28	80/9376	4.18571428571429	IGF1	1.56606239430163
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/28	82/9376	4.08362369337979	LGMN	1.53487236959022
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	2/28	308/9376	2.17439703153989	MT-ND1/AP2A2	1.14693775564899
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/28	90/9376	3.72063492063492	IGF1	1.41932706773096
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/28	98/9376	3.41690962099125	MARCKS	1.31628995255868
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/28	99/9376	3.38239538239538	IGF1	1.30416625774561
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/28	99/9376	3.38239538239538	IGF1	1.30416625774561
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/28	99/9376	3.38239538239538	IGF1	1.30416625774561
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/28	100/9376	3.34857142857143	IL2RA	1.29219693091837
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/28	100/9376	3.34857142857143	IL2RA	1.29219693091837
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/28	333/9376	2.01115401115401	COL1A1/COL1A2	1.02822571823441
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/28	104/9376	3.21978021978022	PLD3	1.24579113838811
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/28	105/9376	3.1891156462585	IGF1	1.23454056871824
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/28	109/9376	3.07208387942333	IL2RA	1.19084791728458
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/28	110/9376	3.04415584415584	IGF1	1.18023774466725
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/28	110/9376	3.04415584415584	IGF1	1.18023774466725
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/28	122/9376	2.74473067915691	IGF1	1.0615705637537
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/28	122/9376	2.74473067915691	IGF1	1.0615705637537
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/28	133/9376	2.51772287862513	IGF1	0.964755197245632
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/28	136/9376	2.46218487394958	IL2RA	0.940028579300301
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/28	138/9376	2.42650103519669	MT-ND1	0.923906361468261
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/28	138/9376	2.42650103519669	IGF1	0.923906361468261
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/28	144/9376	2.32539682539683	IGF1	0.877171628297885
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/28	148/9376	2.26254826254826	IGF1	0.847286633853201
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/28	149/9376	2.24736337488015	MT-ND1	0.839964949645983
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/28	155/9376	2.16036866359447	MSR1	0.797219902012292
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/28	158/9376	2.11934900542495	IGF1	0.776570719157807
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/28	160/9376	2.09285714285714	SIGLEC1	0.763057834011308
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/28	168/9376	1.99319727891156	IL2RA	0.710907029523862
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/28	178/9376	1.88121990369181	SFRP4	0.649610294052663
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/28	184/9376	1.81987577639752	NRP1	0.614691575218536
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/28	212/9376	1.57951482479784	IGF1	0.467084270775639
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/28	227/9376	1.47514159848962	MT-ND1	0.396601608488812
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/28	235/9376	1.42492401215805	MT-ND1	0.361038613038777
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/28	238/9376	1.40696278511405	IGF1	0.348034983718083
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/28	268/9376	1.24946695095949	MT-ND1	0.22676405115317
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/28	298/9376	1.12368168744008	IL2RA	0.118747300825402
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/28	300/9376	1.11619047619048	IGF1	0.111941009049213
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/28	323/9376	1.03670942061035	MARCKS	0.0367441185006352
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/28	368/9376	0.909937888198758	MT-ND1	-0.0964621969358229
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/28	388/9376	0.863033873343152	MT-ND1	-0.150800508926641
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	1/28	480/9376	0.697619047619048	MT-ND1	-0.372205652398103