ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0050661 NADP binding 3/29 54/18639 0.0555555555555556 35.7068965517241 7.96290334989086e-05 0.0121036130918341 GO:0008093 cytoskeletal anchor activity 2/29 22/18639 0.0909090909090909 58.4294670846395 0.000529614027852728 0.0335478498299512 GO:0005200 structural constituent of cytoskeleton 3/29 112/18639 0.0267857142857143 17.2158251231527 0.00068868448892844 0.0335478498299512 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/29 122/18639 0.0245901639344262 15.8046919163369 0.000882838153419767 0.0335478498299512 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3/29 132/18639 0.0227272727272727 14.6073667711599 0.00110869638568414 0.0337043701247979 GO:0071949 FAD binding 2/29 40/18639 0.05 32.1362068965517 0.00175754251815747 0.0445244104599893 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/29 52/18639 0.0384615384615385 24.7201591511936 0.00295349876655245 0.0604436471991522 GO:0051287 NAD binding 2/29 54/18639 0.037037037037037 23.8045977011494 0.00318124458942906 0.0604436471991522 GO:0050660 flavin adenine dinucleotide binding 2/29 86/18639 0.0232558139534884 14.9470729751403 0.007879349151633 0.113073548444578 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/29 88/18639 0.0227272727272727 14.6073667711599 0.00823647596178095 0.113073548444578 GO:0004867 serine-type endopeptidase inhibitor activity 2/29 95/18639 0.0210526315789474 13.5310344827586 0.00954278154970311 0.113073548444578 GO:0015291 secondary active transmembrane transporter activity 3/29 287/18639 0.0104529616724739 6.71837077976691 0.00981924554724037 0.113073548444578 GO:0004222 metalloendopeptidase activity 2/29 110/18639 0.0181818181818182 11.6858934169279 0.0126299034702869 0.113073548444578 GO:0015294 solute:monoatomic cation symporter activity 2/29 116/18639 0.0172413793103448 11.0814506539834 0.0139714621715542 0.113073548444578 GO:0045296 cadherin binding 3/29 334/18639 0.00898203592814371 5.77297129878175 0.0147621590700692 0.113073548444578 GO:0004090 carbonyl reductase (NADPH) activity 1/29 10/18639 0.1 64.2724137931035 0.0154539967144554 0.113073548444578 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/29 10/18639 0.1 64.2724137931035 0.0154539967144554 0.113073548444578 GO:0015173 aromatic amino acid transmembrane transporter activity 1/29 11/18639 0.0909090909090909 58.4294670846395 0.0169866519345573 0.113073548444578 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/29 11/18639 0.0909090909090909 58.4294670846395 0.0169866519345573 0.113073548444578 GO:0048407 platelet-derived growth factor binding 1/29 11/18639 0.0909090909090909 58.4294670846395 0.0169866519345573 0.113073548444578 GO:0002020 protease binding 2/29 136/18639 0.0147058823529412 9.45182555780933 0.0188647911368057 0.113073548444578 GO:0035673 oligopeptide transmembrane transporter activity 1/29 13/18639 0.0769230769230769 49.4403183023873 0.0200450544493924 0.113073548444578 GO:0061459 L-arginine transmembrane transporter activity 1/29 13/18639 0.0769230769230769 49.4403183023873 0.0200450544493924 0.113073548444578 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/29 13/18639 0.0769230769230769 49.4403183023873 0.0200450544493924 0.113073548444578 GO:0020037 heme binding 2/29 142/18639 0.0140845070422535 9.05245264691598 0.0204549108919711 0.113073548444578 GO:0015293 symporter activity 2/29 146/18639 0.0136986301369863 8.80444024563061 0.0215452858529032 0.113073548444578 GO:0043176 amine binding 1/29 14/18639 0.0714285714285714 45.9088669950739 0.0215708084180904 0.113073548444578 GO:1901474 azole transmembrane transporter activity 1/29 14/18639 0.0714285714285714 45.9088669950739 0.0215708084180904 0.113073548444578 GO:0046906 tetrapyrrole binding 2/29 152/18639 0.0131578947368421 8.45689655172414 0.0232254925434599 0.113073548444578 GO:0004708 MAP kinase kinase activity 1/29 16/18639 0.0625 40.1702586206897 0.0246154384280356 0.113073548444578 GO:0016722 oxidoreductase activity, acting on metal ions 1/29 16/18639 0.0625 40.1702586206897 0.0246154384280356 0.113073548444578 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/29 16/18639 0.0625 40.1702586206897 0.0246154384280356 0.113073548444578 GO:0004866 endopeptidase inhibitor activity 2/29 161/18639 0.0124223602484472 7.98415078175198 0.0258441479036081 0.113073548444578 GO:0005178 integrin binding 2/29 161/18639 0.0124223602484472 7.98415078175198 0.0258441479036081 0.113073548444578 GO:0070402 NADPH binding 1/29 17/18639 0.0588235294117647 37.8073022312373 0.0261343211153355 0.113073548444578 GO:0015103 inorganic anion transmembrane transporter activity 2/29 165/18639 0.0121212121212121 7.79059561128527 0.027045075570031 0.113073548444578 GO:0005201 extracellular matrix structural constituent 2/29 168/18639 0.0119047619047619 7.65147783251231 0.0279604773857988 0.113073548444578 GO:0030414 peptidase inhibitor activity 2/29 169/18639 0.0118343195266272 7.60620281575189 0.0282683871111446 0.113073548444578 GO:0015174 basic amino acid transmembrane transporter activity 1/29 21/18639 0.0476190476190476 30.6059113300493 0.0321870470676945 0.117998987350449 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/29 21/18639 0.0476190476190476 30.6059113300493 0.0321870470676945 0.117998987350449 GO:0008237 metallopeptidase activity 2/29 184/18639 0.0108695652173913 6.98613193403298 0.0330500108456349 0.117998987350449 GO:0061135 endopeptidase regulator activity 2/29 184/18639 0.0108695652173913 6.98613193403298 0.0330500108456349 0.117998987350449 GO:0022804 active transmembrane transporter activity 3/29 457/18639 0.00656455142231947 4.21919565381423 0.0333812924741402 0.117998987350449 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/29 23/18639 0.0434782608695652 27.9445277361319 0.0351997734127414 0.121278615683842 GO:0005315 phosphate transmembrane transporter activity 1/29 24/18639 0.0416666666666667 26.7801724137931 0.0367027389569521 0.121278615683842 GO:0015295 solute:proton symporter activity 1/29 24/18639 0.0416666666666667 26.7801724137931 0.0367027389569521 0.121278615683842 GO:0030507 spectrin binding 1/29 26/18639 0.0384615384615385 24.7201591511936 0.0397018912076957 0.128397605607867 GO:0051537 2 iron, 2 sulfur cluster binding 1/29 28/18639 0.0357142857142857 22.9544334975369 0.0426920268466456 0.135191418347711 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/29 30/18639 0.0333333333333333 21.4241379310345 0.0456731720159113 0.136061957609004 GO:0033612 receptor serine/threonine kinase binding 1/29 30/18639 0.0333333333333333 21.4241379310345 0.0456731720159113 0.136061957609004 GO:0005452 solute:inorganic anion antiporter activity 1/29 31/18639 0.032258064516129 20.7330367074527 0.0471603813238556 0.136061957609004 GO:0061134 peptidase regulator activity 2/29 226/18639 0.00884955752212389 5.68782422947818 0.0479591767219814 0.136061957609004 GO:0015106 bicarbonate transmembrane transporter activity 1/29 32/18639 0.03125 20.0851293103448 0.0486453527846041 0.136061957609004 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/29 32/18639 0.03125 20.0851293103448 0.0486453527846041 0.136061957609004 GO:0042923 neuropeptide binding 1/29 33/18639 0.0303030303030303 19.4764890282132 0.0501280896454224 0.136061957609004 GO:0140416 transcription regulator inhibitor activity 1/29 33/18639 0.0303030303030303 19.4764890282132 0.0501280896454224 0.136061957609004 GO:0016229 steroid dehydrogenase activity 1/29 35/18639 0.0285714285714286 18.3635467980296 0.053086872533649 0.141564993423064 GO:0004033 aldo-keto reductase (NADPH) activity 1/29 36/18639 0.0277777777777778 17.8534482758621 0.0545629250329249 0.142992493189734 GO:0005501 retinoid binding 1/29 38/18639 0.0263157894736842 16.9137931034483 0.0575083682875641 0.143299540650979 GO:0019840 isoprenoid binding 1/29 38/18639 0.0263157894736842 16.9137931034483 0.0575083682875641 0.143299540650979 GO:0042887 amide transmembrane transporter activity 1/29 38/18639 0.0263157894736842 16.9137931034483 0.0575083682875641 0.143299540650979 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/29 40/18639 0.025 16.0681034482759 0.0604449506920435 0.148187621051461 GO:0008307 structural constituent of muscle 1/29 42/18639 0.0238095238095238 15.3029556650246 0.06337269795343 0.152662714070936 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/29 43/18639 0.0232558139534884 14.9470729751403 0.0648332664192767 0.152662714070936 GO:0008514 organic anion transmembrane transporter activity 2/29 269/18639 0.00743494423791822 4.7786181258813 0.0652833974645449 0.152662714070936 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/29 44/18639 0.0227272727272727 14.6073667711599 0.0662916357069643 0.152671645870584 GO:0005504 fatty acid binding 1/29 47/18639 0.0212765957446809 13.6749816581071 0.0706535804108926 0.160288719738145 GO:0016860 intramolecular oxidoreductase activity 1/29 53/18639 0.0188679245283019 12.1268705270007 0.079318521688572 0.175782284881353 GO:0031625 ubiquitin protein ligase binding 2/29 302/18639 0.00662251655629139 4.25645124457639 0.0797959056369302 0.175782284881353 GO:0004601 peroxidase activity 1/29 57/18639 0.0175438596491228 11.2758620689655 0.0850517580698786 0.184683817523165 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/29 58/18639 0.0172413793103448 11.0814506539834 0.086479672127352 0.185139579765599 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/29 59/18639 0.0169491525423729 10.8936294564582 0.0879054344387619 0.185405494922009 GO:0044389 ubiquitin-like protein ligase binding 2/29 322/18639 0.0062111801242236 3.99207539087599 0.0890434284822807 0.185405494922009 GO:0015179 L-amino acid transmembrane transporter activity 1/29 62/18639 0.0161290322580645 10.3665183537264 0.0921698421433818 0.189321837916135 GO:0008080 N-acetyltransferase activity 1/29 69/18639 0.0144927536231884 9.31484257871064 0.102045397268186 0.206812005130191 GO:0141003 histone H2AX kinase activity 2/29 354/18639 0.00564971751412429 3.6312098188194 0.104468665926841 0.207677192398748 GO:0140996 histone H3 kinase activity 2/29 357/18639 0.00560224089635854 3.60069545059403 0.105951366852404 0.207677192398748 GO:0035173 histone kinase activity 2/29 360/18639 0.00555555555555556 3.57068965517241 0.107439982707446 0.207677192398748 GO:0106310 protein serine kinase activity 2/29 361/18639 0.00554016620498615 3.56079854809437 0.107937488154613 0.207677192398748 GO:0051536 iron-sulfur cluster binding 1/29 76/18639 0.0131578947368421 8.45689655172414 0.111817189624317 0.209849492067605 GO:0051540 metal cluster binding 1/29 77/18639 0.012987012987013 8.34706672637707 0.113204750982982 0.209849492067605 GO:0015370 solute:sodium symporter activity 1/29 79/18639 0.0126582278481013 8.1357485814055 0.115973597510355 0.209849492067605 GO:0033293 monocarboxylic acid binding 1/29 79/18639 0.0126582278481013 8.1357485814055 0.115973597510355 0.209849492067605 GO:0046332 SMAD binding 1/29 79/18639 0.0126582278481013 8.1357485814055 0.115973597510355 0.209849492067605 GO:0001618 virus receptor activity 1/29 81/18639 0.0123456790123457 7.93486590038314 0.118734096061289 0.209849492067605 GO:0015101 organic cation transmembrane transporter activity 1/29 81/18639 0.0123456790123457 7.93486590038314 0.118734096061289 0.209849492067605 GO:0140272 exogenous protein binding 1/29 82/18639 0.0121951219512195 7.8380992430614 0.120111222433432 0.209849492067605 GO:0016209 antioxidant activity 1/29 86/18639 0.0116279069767442 7.47353648757017 0.125598979163329 0.216943691282113 GO:0004175 endopeptidase activity 2/29 405/18639 0.00493827160493827 3.17394636015326 0.130424336309791 0.222747181113351 GO:0004857 enzyme inhibitor activity 2/29 416/18639 0.00480769230769231 3.0900198938992 0.136212185975581 0.227959118018892 GO:0016410 N-acyltransferase activity 1/29 94/18639 0.0106382978723404 6.83749082905356 0.136475524603415 0.227959118018892 GO:0016407 acetyltransferase activity 1/29 96/18639 0.0104166666666667 6.69504310344828 0.139174182343013 0.229939953436282 GO:0004674 protein serine/threonine kinase activity 2/29 433/18639 0.0046189376443418 2.96870271561679 0.145272122597256 0.237434006825622 GO:0015171 amino acid transmembrane transporter activity 1/29 102/18639 0.00980392156862745 6.30121703853955 0.147221387417875 0.238060115824648 GO:0008013 beta-catenin binding 1/29 106/18639 0.00943396226415094 6.06343526350033 0.152545786858462 0.24407325897354 GO:0035401 histone H3Y41 kinase activity 1/29 115/18639 0.00869565217391304 5.58890554722639 0.164408589837864 0.257030043812879 GO:0140801 histone H2AXY142 kinase activity 1/29 115/18639 0.00869565217391304 5.58890554722639 0.164408589837864 0.257030043812879 GO:0009055 electron transfer activity 1/29 116/18639 0.00862068965517241 5.54072532699168 0.165716738774093 0.257030043812879 GO:0008528 G protein-coupled peptide receptor activity 1/29 122/18639 0.00819672131147541 5.26823063877897 0.173524206844221 0.266421004447693 GO:0001653 peptide receptor activity 1/29 128/18639 0.0078125 5.02128232758621 0.181261107010678 0.275516882656231 GO:0015297 antiporter activity 1/29 135/18639 0.00740740740740741 4.76091954022989 0.190199121066749 0.282555108409856 GO:0019838 growth factor binding 1/29 136/18639 0.00735294117647059 4.72591277890467 0.191468264251415 0.282555108409856 GO:0044325 transmembrane transporter binding 1/29 136/18639 0.00735294117647059 4.72591277890467 0.191468264251415 0.282555108409856 GO:0004713 protein tyrosine kinase activity 1/29 140/18639 0.00714285714285714 4.59088669950739 0.196525659457874 0.287229809976893 GO:0008509 monoatomic anion transmembrane transporter activity 1/29 149/18639 0.00671140939597315 4.31358481832909 0.207793371484441 0.300805642529857 GO:0005506 iron ion binding 1/29 154/18639 0.00649350649350649 4.17353336318854 0.213987127435503 0.30684946575657 GO:0015081 sodium ion transmembrane transporter activity 1/29 164/18639 0.00609756097560976 3.9190496215307 0.226234676559611 0.321380101280943 GO:0008201 heparin binding 1/29 172/18639 0.00581395348837209 3.73676824378508 0.23589984889085 0.33200719473527 GO:0016853 isomerase activity 1/29 180/18639 0.00555555555555556 3.57068965517241 0.245448405454346 0.341403771725401 GO:0015078 proton transmembrane transporter activity 1/29 185/18639 0.00540540540540541 3.47418452935694 0.251357638125926 0.341403771725401 GO:0031406 carboxylic acid binding 1/29 187/18639 0.0053475935828877 3.43702747556703 0.253708798522913 0.341403771725401 GO:0046943 carboxylic acid transmembrane transporter activity 1/29 188/18639 0.00531914893617021 3.41874541452678 0.254881703619533 0.341403771725401 GO:0005342 organic acid transmembrane transporter activity 1/29 189/18639 0.00529100529100529 3.40065681444992 0.256052828794051 0.341403771725401 GO:0043177 organic acid binding 1/29 189/18639 0.00529100529100529 3.40065681444992 0.256052828794051 0.341403771725401 GO:0051015 actin filament binding 1/29 209/18639 0.00478468899521531 3.07523510971787 0.279105533257729 0.345917294777252 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/29 229/18639 0.00436681222707424 2.80665562415299 0.301467795660016 0.345917294777252 GO:0000287 magnesium ion binding 1/29 230/18639 0.00434782608695652 2.79445277361319 0.302568145139964 0.345917294777252 GO:0005539 glycosaminoglycan binding 1/29 242/18639 0.00413223140495868 2.65588486748361 0.315642495651561 0.345917294777252 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/29 243/18639 0.00411522633744856 2.64495530012771 0.316721278476267 0.345917294777252 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0004711 ribosomal protein S6 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0035175 histone H3S10 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0035979 histone H2AXS139 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0044022 histone H3S28 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0044023 histone H4S1 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0044024 histone H2AS1 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0044025 histone H2BS14 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0072354 histone H3T3 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0072371 histone H2AS121 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0140823 histone H2BS36 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0140855 histone H3S57 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0140995 histone H2A kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0140997 histone H4 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0140998 histone H2B kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:1990244 histone H2AT120 kinase activity 1/29 245/18639 0.00408163265306122 2.62336382828994 0.318873920586793 0.345917294777252 GO:0004677 DNA-dependent protein kinase activity 1/29 246/18639 0.0040650406504065 2.61269974768713 0.31994778468938 0.345917294777252 GO:0140857 histone H3T45 kinase activity 1/29 246/18639 0.0040650406504065 2.61269974768713 0.31994778468938 0.345917294777252 GO:0035402 histone H3T11 kinase activity 1/29 247/18639 0.00404858299595142 2.60212201591512 0.32102001402902 0.345917294777252 GO:0035403 histone H3T6 kinase activity 1/29 247/18639 0.00404858299595142 2.60212201591512 0.32102001402902 0.345917294777252 GO:0004679 AMP-activated protein kinase activity 1/29 248/18639 0.00403225806451613 2.59162958843159 0.322090611005594 0.345917294777252 GO:0042277 peptide binding 1/29 249/18639 0.00401606425702811 2.58122143747403 0.323159578015591 0.345917294777252 GO:1901681 sulfur compound binding 1/29 275/18639 0.00363636363636364 2.33717868338558 0.350388372971164 0.372440788053265 GO:0030246 carbohydrate binding 1/29 280/18639 0.00357142857142857 2.29544334975369 0.355502011282032 0.375252123019923 GO:0031267 small GTPase binding 1/29 283/18639 0.00353356890459364 2.27111002802486 0.358551515383931 0.375860898885224 GO:0051020 GTPase binding 1/29 315/18639 0.00317460317460317 2.04039408866995 0.390224768908824 0.406261403247542 GO:0003924 GTPase activity 1/29 331/18639 0.00302114803625378 1.94176476716325 0.405489731648375 0.419281899391517 GO:0016887 ATP hydrolysis activity 1/29 417/18639 0.00239808153477218 1.54130488712478 0.481423446936367 0.494434891448161 GO:0003779 actin binding 1/29 443/18639 0.00225733634311512 1.45084455514906 0.502474063827376 0.512590991286988 GO:0046873 metal ion transmembrane transporter activity 1/29 450/18639 0.00222222222222222 1.42827586206897 0.507999049814313 0.514772370478504 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 1/29 484/18639 0.00206611570247934 1.32794243374181 0.534002865072656 0.537539307887706 GO:0001216 DNA-binding transcription activator activity 1/29 491/18639 0.00203665987780041 1.30901046421799 0.539189358717378 0.539189358717378