ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0005201	extracellular matrix structural constituent	45/1691	168/18639	0.267857142857143	2.95244783306581	1.84479778273498e-11	2.2524980927194e-08
GO:0005539	glycosaminoglycan binding	52/1691	242/18639	0.214876033057851	2.36846503853654	3.14393524582997e-09	1.91937246757919e-06
GO:0008201	heparin binding	38/1691	172/18639	0.22093023255814	2.43519728246668	1.89812579219754e-07	6.39223388375173e-05
GO:0005518	collagen binding	22/1691	72/18639	0.305555555555556	3.36797752808989	2.13563920752848e-07	6.39223388375173e-05
GO:1901681	sulfur compound binding	52/1691	275/18639	0.189090909090909	2.08424923391216	2.61762239301873e-07	6.39223388375173e-05
GO:0001217	DNA-binding transcription repressor activity	49/1691	278/18639	0.176258992805755	1.94280979710614	4.6454017977621e-06	0.000856777943069429
GO:0045296	cadherin binding	56/1691	334/18639	0.167664670658683	1.84807912265357	4.9119128595299e-06	0.000856777943069429
GO:0005178	integrin binding	33/1691	161/18639	0.204968944099379	2.25926442878079	6.68846559256921e-06	0.00100423470615484
GO:0140297	DNA-binding transcription factor binding	74/1691	488/18639	0.151639344262295	1.67144041259901	7.40222142128876e-06	0.00100423470615484
GO:0019838	growth factor binding	29/1691	136/18639	0.213235294117647	2.35038003965631	1.07144865639504e-05	0.00130823880945835
GO:0003735	structural constituent of ribosome	34/1691	175/18639	0.194285714285714	2.1415088282504	1.62955285829965e-05	0.00180880367271261
GO:0001221	transcription coregulator binding	25/1691	115/18639	0.217391304347826	2.3961895456766	3.01110206318691e-05	0.00306379634929268
GO:0019955	cytokine binding	29/1691	144/18639	0.201388888888889	2.21980337078652	3.3376358297523e-05	0.00308940773113665
GO:0005126	cytokine receptor binding	46/1691	275/18639	0.167272727272727	1.84375893769152	3.54231844683973e-05	0.00308940773113665
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	45/1691	268/18639	0.167910447761194	1.85078819386215	3.89717727724476e-05	0.00317230230367723
GO:0061134	peptidase regulator activity	39/1691	226/18639	0.172566371681416	1.90210798448842	6.7748405895605e-05	0.00517005022490835
GO:0003779	actin binding	65/1691	443/18639	0.146726862302483	1.61729271818804	7.22239920160336e-05	0.00518738201479865
GO:0005158	insulin receptor binding	9/1691	23/18639	0.391304347826087	4.31314118221788	0.000102621254246518	0.00696114174638884
GO:0044389	ubiquitin-like protein ligase binding	50/1691	322/18639	0.15527950310559	1.71156396119757	0.000118355321161902	0.0076058866915096
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	53/1691	349/18639	0.151862464183381	1.67389974566176	0.000134895440998875	0.0082353666729813
GO:0034713	type I transforming growth factor beta receptor binding	6/1691	11/18639	0.545454545454545	6.01225740551583	0.000170960474437722	0.00994013044230757
GO:0005160	transforming growth factor beta receptor binding	9/1691	26/18639	0.346153846153846	3.81547104580812	0.000305420347407528	0.0163257500797046
GO:0043394	proteoglycan binding	11/1691	37/18639	0.297297297297297	3.27695110841178	0.000307528461779857	0.0163257500797046
GO:0001540	amyloid-beta binding	18/1691	83/18639	0.216867469879518	2.39041559496413	0.000386821397014716	0.0196795385731237
GO:0016504	peptidase activator activity	14/1691	57/18639	0.245614035087719	2.70727380248374	0.000445652832097951	0.0212592720261699
GO:0005010	insulin-like growth factor receptor activity	13/1691	51/18639	0.254901960784314	2.80964970257766	0.000480575207658952	0.0212592720261699
GO:0140416	transcription regulator inhibitor activity	10/1691	33/18639	0.303030303030303	3.34014300306435	0.000484904849769383	0.0212592720261699
GO:0008013	beta-catenin binding	21/1691	106/18639	0.19811320754717	2.18369726521094	0.000487518113622243	0.0212592720261699
GO:0019199	transmembrane receptor protein kinase activity	17/1691	78/18639	0.217948717948718	2.40233362143475	0.000522785731273715	0.0213184306007716
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	66/1691	484/18639	0.136363636363636	1.50306435137896	0.000529707279918706	0.0213184306007716
GO:0043560	insulin receptor substrate binding	6/1691	13/18639	0.461538461538462	5.08729472774417	0.000541254175777165	0.0213184306007716
GO:0017124	SH3 domain binding	22/1691	115/18639	0.191304347826087	2.10864680019541	0.000599356214508058	0.0224028053133098
GO:0031625	ubiquitin protein ligase binding	45/1691	302/18639	0.149006622516556	1.64242131110946	0.000630975528411838	0.0224028053133098
GO:0004022	alcohol dehydrogenase (NAD+) activity	8/1691	23/18639	0.347826086956522	3.83390327308256	0.000638028357278611	0.0224028053133098
GO:0001786	phosphatidylserine binding	14/1691	59/18639	0.23728813559322	2.6155018091792	0.000648611055429606	0.0224028053133098
GO:0070851	growth factor receptor binding	25/1691	139/18639	0.179856115107914	1.98245897663891	0.00069100690763265	0.0224028053133098
GO:0048306	calcium-dependent protein binding	17/1691	80/18639	0.2125	2.34227528089888	0.000711070349820846	0.0224028053133098
GO:0005003	ephrin receptor activity	13/1691	53/18639	0.245283018867925	2.70362518549926	0.000715568720081148	0.0224028053133098
GO:0005005	transmembrane-ephrin receptor activity	13/1691	53/18639	0.245283018867925	2.70362518549926	0.000715568720081148	0.0224028053133098
GO:0004714	transmembrane receptor protein tyrosine kinase activity	14/1691	60/18639	0.233333333333333	2.57191011235955	0.000776426278007511	0.0231896769611172
GO:0001216	DNA-binding transcription activator activity	66/1691	491/18639	0.134419551934827	1.48163573537152	0.000778686941364295	0.0231896769611172
GO:0004222	metalloendopeptidase activity	21/1691	110/18639	0.190909090909091	2.10429009193054	0.000811843175467408	0.0236014408868025
GO:0051020	GTPase binding	46/1691	315/18639	0.146031746031746	1.60963081861958	0.000856234562099626	0.0237333741301855
GO:0008191	metalloendopeptidase inhibitor activity	6/1691	14/18639	0.428571428571429	4.7239165329053	0.000874694378262366	0.0237333741301855
GO:0042043	neurexin family protein binding	6/1691	14/18639	0.428571428571429	4.7239165329053	0.000874694378262366	0.0237333741301855
GO:0042056	chemoattractant activity	11/1691	42/18639	0.261904761904762	2.8868378812199	0.00100892714883604	0.0238416468649119
GO:0004955	prostaglandin receptor activity	5/1691	10/18639	0.5	5.51123595505618	0.00104294224783569	0.0238416468649119
GO:0098631	cell adhesion mediator activity	16/1691	76/18639	0.210526315789474	2.32052040212892	0.00112050772372345	0.0238416468649119
GO:0005004	GPI-linked ephrin receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0005008	hepatocyte growth factor receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0005009	insulin receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0005011	macrophage colony-stimulating factor receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0005018	platelet-derived growth factor alpha-receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0005020	stem cell factor receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0008288	boss receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0036332	placental growth factor receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0038062	protein tyrosine kinase collagen receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0060175	brain-derived neurotrophic factor receptor activity	12/1691	49/18639	0.244897959183673	2.69938087594588	0.00115158487817978	0.0238416468649119
GO:0044325	transmembrane transporter binding	24/1691	136/18639	0.176470588235294	1.94514210178453	0.00115205337021278	0.0238416468649119
GO:0097110	scaffold protein binding	15/1691	70/18639	0.214285714285714	2.36195826645265	0.00130917567874409	0.0261493531635801
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	7/1691	20/18639	0.35	3.85786516853933	0.00134108625718261	0.0261493531635801
GO:0005006	epidermal growth factor receptor activity	12/1691	50/18639	0.24	2.64539325842697	0.0013920622077254	0.0261493531635801
GO:0005007	fibroblast growth factor receptor activity	12/1691	50/18639	0.24	2.64539325842697	0.0013920622077254	0.0261493531635801
GO:0005017	platelet-derived growth factor receptor activity	12/1691	50/18639	0.24	2.64539325842697	0.0013920622077254	0.0261493531635801
GO:0005019	platelet-derived growth factor beta-receptor activity	12/1691	50/18639	0.24	2.64539325842697	0.0013920622077254	0.0261493531635801
GO:0003714	transcription corepressor activity	32/1691	204/18639	0.156862745098039	1.72901520158625	0.00156252440991052	0.0289067015833447
GO:0043548	phosphatidylinositol 3-kinase binding	8/1691	26/18639	0.307692307692308	3.39152981849611	0.00158923691282516	0.0289620637396944
GO:0033218	amide binding	37/1691	247/18639	0.149797570850202	1.65113951689942	0.00166154382281947	0.0291735230017031
GO:0005021	vascular endothelial growth factor receptor activity	12/1691	51/18639	0.235294117647059	2.59352280237938	0.00167251974620738	0.0291735230017031
GO:0005030	neurotrophin receptor activity	12/1691	51/18639	0.235294117647059	2.59352280237938	0.00167251974620738	0.0291735230017031
GO:0004954	prostanoid receptor activity	5/1691	11/18639	0.454545454545455	5.01021450459653	0.00176959372566732	0.0300093602644417
GO:0097493	structural molecule activity conferring elasticity	5/1691	11/18639	0.454545454545455	5.01021450459653	0.00176959372566732	0.0300093602644417
GO:0031267	small GTPase binding	41/1691	283/18639	0.144876325088339	1.59689522372653	0.00184602444344417	0.0306161823747151
GO:0036122	BMP binding	7/1691	21/18639	0.333333333333333	3.67415730337079	0.00185552620452819	0.0306161823747151
GO:0008142	oxysterol binding	6/1691	16/18639	0.375	4.13342696629214	0.00199006960075555	0.0323983331003003
GO:0001618	virus receptor activity	16/1691	81/18639	0.197530864197531	2.1772784019975	0.00225851791855659	0.0362848734020736
GO:0061135	endopeptidase regulator activity	29/1691	184/18639	0.157608695652174	1.73723742061553	0.00234744966444482	0.0367308622264494
GO:0038064	collagen receptor activity	12/1691	53/18639	0.226415094339623	2.49565401738393	0.0023730919122264	0.0367308622264494
GO:0050840	extracellular matrix binding	14/1691	67/18639	0.208955223880597	2.30320308569512	0.00240589869332255	0.0367308622264494
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	17/1691	89/18639	0.191011235955056	2.10541598283045	0.00243669110593153	0.0367308622264494
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	17/1691	89/18639	0.191011235955056	2.10541598283045	0.00243669110593153	0.0367308622264494
GO:0008093	cytoskeletal anchor activity	7/1691	22/18639	0.318181818181818	3.50715015321757	0.00251059852678029	0.0369330217011896
GO:0030021	extracellular matrix structural constituent conferring compression resistance	7/1691	22/18639	0.318181818181818	3.50715015321757	0.00251059852678029	0.0369330217011896
GO:0140272	exogenous protein binding	16/1691	82/18639	0.195121951219512	2.15072622636339	0.00257463177150181	0.0374241118214727
GO:0004175	endopeptidase activity	54/1691	405/18639	0.133333333333333	1.46966292134831	0.00265957383745191	0.038019547716706
GO:0005543	phospholipid binding	64/1691	497/18639	0.128772635814889	1.41939276106075	0.00267787150174997	0.038019547716706
GO:0004866	endopeptidase inhibitor activity	26/1691	161/18639	0.161490683229814	1.78002651964547	0.00272981860563214	0.0380968852901052
GO:0140793	histone H2AXY142 phosphatase activity	17/1691	90/18639	0.188888888888889	2.08202247191011	0.00275569394886502	0.0380968852901052
GO:0032934	sterol binding	14/1691	68/18639	0.205882352941176	2.26933245208196	0.00278175408740574	0.0380968852901052
GO:0005165	neurotrophin receptor binding	5/1691	12/18639	0.416666666666667	4.59269662921348	0.00280812422285787	0.0380968852901052
GO:0038191	neuropilin binding	6/1691	17/18639	0.352941176470588	3.89028420356907	0.00284153393018836	0.0381265157006592
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	21/1691	122/18639	0.172131147540984	1.8973107386259	0.00309838904191065	0.0411210110888359
GO:0098632	cell-cell adhesion mediator activity	12/1691	55/18639	0.218181818181818	2.40490296220633	0.00329601384863278	0.0432734721417272
GO:0042277	peptide binding	36/1691	249/18639	0.144578313253012	1.59361039664275	0.0034912024158707	0.0453484909550864
GO:0003746	translation elongation factor activity	6/1691	18/18639	0.333333333333333	3.67415730337079	0.00393862909052409	0.0500944387451033
GO:0004706	JUN kinase kinase kinase activity	6/1691	18/18639	0.333333333333333	3.67415730337079	0.00393862909052409	0.0500944387451033
GO:0003924	GTPase activity	45/1691	331/18639	0.13595166163142	1.49852337146543	0.0040019006160894	0.0503744397138677
GO:0031994	insulin-like growth factor I binding	5/1691	13/18639	0.384615384615385	4.23941227312014	0.00422491800228332	0.0526390293957952
GO:0046332	SMAD binding	15/1691	79/18639	0.189873417721519	2.09287441331247	0.00452273505797439	0.0557803990483508
GO:0004857	enzyme inhibitor activity	54/1691	416/18639	0.129807692307692	1.43080164217805	0.00466810141796324	0.0569975183133311
GO:0019843	rRNA binding	13/1691	65/18639	0.2	2.20449438202247	0.00503270104470772	0.060840871045427
GO:0030414	peptidase inhibitor activity	26/1691	169/18639	0.153846153846154	1.69576490924806	0.00530696010313719	0.0630679196888651
GO:0042577	lipid phosphatase activity	6/1691	19/18639	0.315789473684211	3.48078060319338	0.00532022582141941	0.0630679196888651
GO:0005319	lipid transporter activity	27/1691	178/18639	0.151685393258427	1.67194798636536	0.00553389440886588	0.064970048781012
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	11/1691	52/18639	0.211538461538462	2.33167675021608	0.0061498769000431	0.07113740059006
GO:0048029	monosaccharide binding	14/1691	74/18639	0.189189189189189	2.08533252353477	0.00617572847055394	0.07113740059006
GO:0004725	protein tyrosine phosphatase activity	17/1691	98/18639	0.173469387755102	1.912061453795	0.00677082176496828	0.077263302570339
GO:0008066	glutamate receptor activity	7/1691	26/18639	0.269230769230769	2.9675885911841	0.00702366983006999	0.0779627351137769
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	7/1691	26/18639	0.269230769230769	2.9675885911841	0.00702366983006999	0.0779627351137769
GO:0070412	R-SMAD binding	7/1691	26/18639	0.269230769230769	2.9675885911841	0.00702366983006999	0.0779627351137769
GO:0001664	G protein-coupled receptor binding	40/1691	297/18639	0.134680134680135	1.48450800136193	0.00746379294655392	0.0821017224120932
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	21/1691	132/18639	0.159090909090909	1.75357507660878	0.00786304845983231	0.0857212693701362
GO:0004953	icosanoid receptor activity	5/1691	15/18639	0.333333333333333	3.67415730337079	0.00845600310747638	0.0905682438090233
GO:0048531	beta-1,3-galactosyltransferase activity	5/1691	15/18639	0.333333333333333	3.67415730337079	0.00845600310747638	0.0905682438090233
GO:0008237	metallopeptidase activity	27/1691	184/18639	0.146739130434783	1.61742794333171	0.00859242070345295	0.0912290928601396
GO:0005044	scavenger receptor activity	7/1691	27/18639	0.259259259259259	2.85767790262172	0.00875363438170663	0.0917625840132452
GO:1990782	protein tyrosine kinase binding	19/1691	117/18639	0.162393162393162	1.78997407087295	0.00895376294433214	0.0917625840132452
GO:0004252	serine-type endopeptidase activity	26/1691	176/18639	0.147727272727273	1.62831971399387	0.00898814139236438	0.0917625840132452
GO:0005522	profilin binding	4/1691	10/18639	0.4	4.40898876404494	0.00906712148940388	0.0917625840132452
GO:0043121	neurotrophin binding	4/1691	10/18639	0.4	4.40898876404494	0.00906712148940388	0.0917625840132452
GO:0008373	sialyltransferase activity	6/1691	21/18639	0.285714285714286	3.14927768860353	0.009093589406718	0.0917625840132452
GO:1901981	phosphatidylinositol phosphate binding	27/1691	185/18639	0.145945945945946	1.60868508958397	0.00921657342462226	0.092241279930031
GO:0008236	serine-type peptidase activity	28/1691	194/18639	0.144329896907216	1.59087223444921	0.00940914207528642	0.0934029469424774
GO:0016757	glycosyltransferase activity	36/1691	267/18639	0.134831460674157	1.48617598788032	0.0105387284076916	0.103772478917673
GO:0045499	chemorepellent activity	7/1691	28/18639	0.25	2.75561797752809	0.0107766269162538	0.105266091717968
GO:0008083	growth factor activity	24/1691	162/18639	0.148148148148148	1.63295880149813	0.0113471081799614	0.108698225706709
GO:0001222	transcription corepressor binding	10/1691	49/18639	0.204081632653061	2.24948406328824	0.011362603107425	0.108698225706709
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	5/1691	16/18639	0.3125	3.44452247191011	0.0113950637923495	0.108698225706709
GO:0019894	kinesin binding	9/1691	42/18639	0.214285714285714	2.36195826645265	0.0116307136411498	0.110086057022046
GO:0005200	structural constituent of cytoskeleton	18/1691	112/18639	0.160714285714286	1.77146869983949	0.0119368480372637	0.1121145496423
GO:0017171	serine hydrolase activity	28/1691	198/18639	0.141414141414141	1.55873340143003	0.0122547310860883	0.113909755073438
GO:0004896	cytokine receptor activity	16/1691	96/18639	0.166666666666667	1.83707865168539	0.0123145681160473	0.113909755073438
GO:0005125	cytokine activity	32/1691	234/18639	0.136752136752137	1.50734658599827	0.0125514669956593	0.11522812933609
GO:0038024	cargo receptor activity	12/1691	65/18639	0.184615384615385	2.03491789109767	0.0130639758705657	0.117119889200853
GO:0051861	glycolipid binding	7/1691	29/18639	0.241379310344828	2.66059666795816	0.013118373609812	0.117119889200853
GO:0003953	NAD+ nucleosidase activity	4/1691	11/18639	0.363636363636364	4.00817160367722	0.0132371373543962	0.117119889200853
GO:0008046	axon guidance receptor activity	4/1691	11/18639	0.363636363636364	4.00817160367722	0.0132371373543962	0.117119889200853
GO:0032050	clathrin heavy chain binding	4/1691	11/18639	0.363636363636364	4.00817160367722	0.0132371373543962	0.117119889200853
GO:0030971	receptor tyrosine kinase binding	14/1691	81/18639	0.172839506172839	1.90511860174781	0.0136475269932208	0.11988223351599
GO:0004602	glutathione peroxidase activity	6/1691	23/18639	0.260869565217391	2.87542745481192	0.0144677508728443	0.125284566069098
GO:0016849	phosphorus-oxygen lyase activity	6/1691	23/18639	0.260869565217391	2.87542745481192	0.0144677508728443	0.125284566069098
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	5/1691	17/18639	0.294117647058824	3.24190350297422	0.01495903456825	0.127727141313519
GO:0019198	transmembrane receptor protein phosphatase activity	5/1691	17/18639	0.294117647058824	3.24190350297422	0.01495903456825	0.127727141313519
GO:0001223	transcription coactivator binding	9/1691	44/18639	0.204545454545455	2.25459652706844	0.0157079255436865	0.1330791445043
GO:0001968	fibronectin binding	7/1691	30/18639	0.233333333333333	2.57191011235955	0.0158038296094378	0.1330791445043
GO:0070888	E-box binding	11/1691	59/18639	0.186440677966102	2.05503713578366	0.0159154169830946	0.133100850249031
GO:0016500	protein-hormone receptor activity	12/1691	67/18639	0.17910447761194	1.97417407345296	0.0164593429983164	0.136713318373771
GO:0030215	semaphorin receptor binding	6/1691	24/18639	0.25	2.75561797752809	0.0178443415107818	0.145252939897764
GO:0035035	histone acetyltransferase binding	6/1691	24/18639	0.25	2.75561797752809	0.0178443415107818	0.145252939897764
GO:0050431	transforming growth factor beta binding	6/1691	24/18639	0.25	2.75561797752809	0.0178443415107818	0.145252939897764
GO:0140303	intramembrane lipid transporter activity	9/1691	45/18639	0.2	2.20449438202247	0.0180998774106593	0.146357286876921
GO:0035259	nuclear glucocorticoid receptor binding	4/1691	12/18639	0.333333333333333	3.67415730337079	0.0184516439201654	0.146923030736172
GO:0097677	STAT family protein binding	4/1691	12/18639	0.333333333333333	3.67415730337079	0.0184516439201654	0.146923030736172
GO:0017022	myosin binding	13/1691	76/18639	0.171052631578947	1.88542282672975	0.0185308327054631	0.146923030736172
GO:0004970	glutamate-gated receptor activity	5/1691	18/18639	0.277777777777778	3.06179775280899	0.019197652059683	0.150258545928673
GO:0017128	phospholipid scramblase activity	5/1691	18/18639	0.277777777777778	3.06179775280899	0.019197652059683	0.150258545928673
GO:0017046	peptide hormone binding	10/1691	53/18639	0.188679245283019	2.07971168115328	0.0194006088067638	0.150879893968526
GO:0004709	MAP kinase kinase kinase activity	6/1691	25/18639	0.24	2.64539325842697	0.0217234325324727	0.166026591099162
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	8/1691	39/18639	0.205128205128205	2.26101987899741	0.0218078439626117	0.166026591099162
GO:0015485	cholesterol binding	10/1691	54/18639	0.185185185185185	2.04119850187266	0.0219352867577821	0.166026591099162
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/1691	86/18639	0.162790697674419	1.79435589234387	0.0222888724104078	0.166026591099162
GO:0008378	galactosyltransferase activity	7/1691	32/18639	0.21875	2.41116573033708	0.022300049910125	0.166026591099162
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/1691	32/18639	0.21875	2.41116573033708	0.022300049910125	0.166026591099162
GO:0043425	bHLH transcription factor binding	7/1691	32/18639	0.21875	2.41116573033708	0.022300049910125	0.166026591099162
GO:0140996	histone H3 kinase activity	44/1691	357/18639	0.123249299719888	1.35851194410348	0.0228001792868723	0.168721326722855
GO:0016791	phosphatase activity	35/1691	273/18639	0.128205128205128	1.41313742437338	0.0233492346923351	0.171743467224946
GO:0035591	signaling adaptor activity	19/1691	129/18639	0.147286821705426	1.62346485497779	0.0237412090368666	0.172792936177418
GO:0051015	actin filament binding	28/1691	209/18639	0.133971291866029	1.47669480135477	0.0237749494494727	0.172792936177418
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	5/1691	19/18639	0.263157894736842	2.90065050266115	0.0241538757162057	0.173481660291101
GO:0005520	insulin-like growth factor binding	5/1691	19/18639	0.263157894736842	2.90065050266115	0.0241538757162057	0.173481660291101
GO:0005525	GTP binding	46/1691	378/18639	0.121693121693122	1.34135901551632	0.024757374053901	0.17587108812767
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/1691	13/18639	0.307692307692308	3.39152981849611	0.0247746332170018	0.17587108812767
GO:0140662	ATP-dependent protein folding chaperone	8/1691	40/18639	0.2	2.20449438202247	0.0251596990481799	0.177572211201316
GO:0035091	phosphatidylinositol binding	36/1691	284/18639	0.126760563380282	1.39721474916917	0.0253153720657689	0.177644076392551
GO:0035173	histone kinase activity	44/1691	360/18639	0.122222222222222	1.34719101123596	0.0258700995708756	0.180499380434509
GO:0071889	14-3-3 protein binding	7/1691	33/18639	0.212121212121212	2.33810010214505	0.0261542683693696	0.181445236812501
GO:0106310	protein serine kinase activity	44/1691	361/18639	0.121883656509695	1.3434591801799	0.0269628920085409	0.185998255041968
GO:0000287	magnesium ion binding	30/1691	230/18639	0.130434782608696	1.43771372740596	0.0275198594609205	0.188773867425753
GO:0004713	protein tyrosine kinase activity	20/1691	140/18639	0.142857142857143	1.57463884430177	0.0278710500838963	0.190114816494063
GO:0042578	phosphoric ester hydrolase activity	44/1691	363/18639	0.121212121212121	1.33605720122574	0.0292571682684711	0.198461124754462
GO:0141003	histone H2AX kinase activity	43/1691	354/18639	0.121468926553672	1.33888783088935	0.0299298923343318	0.201902754365851
GO:0008376	acetylgalactosaminyltransferase activity	7/1691	34/18639	0.205882352941176	2.26933245208196	0.030438620683681	0.20420635085041
GO:0005104	fibroblast growth factor receptor binding	6/1691	27/18639	0.222222222222222	2.44943820224719	0.031098997617904	0.20749659066372
GO:0008195	phosphatidate phosphatase activity	4/1691	14/18639	0.285714285714286	3.14927768860353	0.0322500251642179	0.212850166083838
GO:0031404	chloride ion binding	4/1691	14/18639	0.285714285714286	3.14927768860353	0.0322500251642179	0.212850166083838
GO:0016758	hexosyltransferase activity	26/1691	197/18639	0.131979695431472	1.45474248559859	0.0335798437492894	0.220435425902593
GO:0072341	modified amino acid binding	14/1691	91/18639	0.153846153846154	1.69576490924806	0.0344883317036278	0.225188518770746
GO:0016229	steroid dehydrogenase activity	7/1691	35/18639	0.2	2.20449438202247	0.0351701595698402	0.228418961887101
GO:0030165	PDZ domain binding	13/1691	83/18639	0.156626506024096	1.72641126302965	0.0357703748045715	0.231087976912073
GO:0005123	death receptor binding	5/1691	21/18639	0.238095238095238	2.62439807383628	0.0363538483485952	0.233621309650709
GO:0019003	GDP binding	12/1691	75/18639	0.16	1.76359550561798	0.0368964592277812	0.234638420401671
GO:0044183	protein folding chaperone	12/1691	75/18639	0.16	1.76359550561798	0.0368964592277812	0.234638420401671
GO:0048156	tau protein binding	8/1691	43/18639	0.186046511627907	2.050692448393	0.037330844827284	0.236170785150849
GO:0042826	histone deacetylase binding	18/1691	127/18639	0.141732283464567	1.56224011324427	0.0380888263292037	0.23972400488638
GO:0140789	histone phosphatase activity	19/1691	136/18639	0.139705882352941	1.53990416391276	0.0384184402347513	0.240558541162212
GO:0019001	guanyl nucleotide binding	47/1691	400/18639	0.1175	1.2951404494382	0.0398590585425873	0.247045230865478
GO:0032561	guanyl ribonucleotide binding	47/1691	400/18639	0.1175	1.2951404494382	0.0398590585425873	0.247045230865478
GO:0004033	aldo-keto reductase (NADPH) activity	7/1691	36/18639	0.194444444444444	2.14325842696629	0.0403637355312269	0.247595145462543
GO:0005041	low-density lipoprotein particle receptor activity	4/1691	15/18639	0.266666666666667	2.93932584269663	0.0409023968212149	0.247595145462543
GO:0005523	tropomyosin binding	4/1691	15/18639	0.266666666666667	2.93932584269663	0.0409023968212149	0.247595145462543
GO:0140776	protein-containing complex destabilizing activity	4/1691	15/18639	0.266666666666667	2.93932584269663	0.0409023968212149	0.247595145462543
GO:0016922	nuclear receptor binding	19/1691	137/18639	0.138686131386861	1.52866398753383	0.0409616866367188	0.247595145462543
GO:0005548	phospholipid transporter activity	11/1691	68/18639	0.161764705882353	1.78304692663582	0.0415188623882698	0.249726753576736
GO:1902936	phosphatidylinositol bisphosphate binding	16/1691	111/18639	0.144144144144144	1.58882477983602	0.0425384081348671	0.254042850839365
GO:0005080	protein kinase C binding	9/1691	52/18639	0.173076923076923	1.90773552290406	0.0426525670942423	0.254042850839365
GO:0042562	hormone binding	14/1691	94/18639	0.148936170212766	1.64164475256993	0.0437903990093771	0.259553772769172
GO:0004674	protein serine/threonine kinase activity	50/1691	433/18639	0.115473441108545	1.27280276098295	0.0453962466296158	0.267772063452951
GO:0015026	coreceptor activity	10/1691	61/18639	0.163934426229508	1.80696260821514	0.0467061110198231	0.27390284500327
GO:0004867	serine-type endopeptidase inhibitor activity	14/1691	95/18639	0.147368421052632	1.62436428149024	0.0472494873861533	0.27390284500327
GO:0008009	chemokine activity	8/1691	45/18639	0.177777777777778	1.95955056179775	0.0473329240750942	0.27390284500327
GO:0042605	peptide antigen binding	8/1691	45/18639	0.177777777777778	1.95955056179775	0.0473329240750942	0.27390284500327
GO:0030246	carbohydrate binding	34/1691	280/18639	0.121428571428571	1.3384430176565	0.0491399661727061	0.282549915194115
GO:0035925	mRNA 3'-UTR AU-rich region binding	6/1691	30/18639	0.2	2.20449438202247	0.0495214429578547	0.282549915194115
GO:0098918	structural constituent of synapse	6/1691	30/18639	0.2	2.20449438202247	0.0495214429578547	0.282549915194115
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	4/1691	16/18639	0.25	2.75561797752809	0.0507381744975033	0.282882698910737
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/1691	16/18639	0.25	2.75561797752809	0.0507381744975033	0.282882698910737
GO:0034450	ubiquitin-ubiquitin ligase activity	4/1691	16/18639	0.25	2.75561797752809	0.0507381744975033	0.282882698910737
GO:0070411	I-SMAD binding	4/1691	16/18639	0.25	2.75561797752809	0.0507381744975033	0.282882698910737
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	4/1691	16/18639	0.25	2.75561797752809	0.0507381744975033	0.282882698910737
GO:0005212	structural constituent of eye lens	5/1691	23/18639	0.217391304347826	2.3961895456766	0.0517504384860376	0.283351055567049
GO:0008171	O-methyltransferase activity	5/1691	23/18639	0.217391304347826	2.3961895456766	0.0517504384860376	0.283351055567049
GO:0099186	structural constituent of postsynapse	5/1691	23/18639	0.217391304347826	2.3961895456766	0.0517504384860376	0.283351055567049
GO:0140103	catalytic activity, acting on a glycoprotein	5/1691	23/18639	0.217391304347826	2.3961895456766	0.0517504384860376	0.283351055567049
GO:0005109	frizzled binding	7/1691	38/18639	0.184210526315789	2.0304553518628	0.0521846048331001	0.284452689737568
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	8/1691	46/18639	0.173913043478261	1.91695163654128	0.0529302027914005	0.287234567148
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/1691	10/18639	0.3	3.30674157303371	0.0550879897056017	0.29117937415818
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/1691	10/18639	0.3	3.30674157303371	0.0550879897056017	0.29117937415818
GO:0030957	Tat protein binding	3/1691	10/18639	0.3	3.30674157303371	0.0550879897056017	0.29117937415818
GO:0032052	bile acid binding	3/1691	10/18639	0.3	3.30674157303371	0.0550879897056017	0.29117937415818
GO:0035256	G protein-coupled glutamate receptor binding	3/1691	10/18639	0.3	3.30674157303371	0.0550879897056017	0.29117937415818
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	3/1691	10/18639	0.3	3.30674157303371	0.0550879897056017	0.29117937415818
GO:0005516	calmodulin binding	26/1691	207/18639	0.1256038647343	1.38446507083537	0.0558883080301993	0.294136310796868
GO:0070325	lipoprotein particle receptor binding	6/1691	31/18639	0.193548387096774	2.13338166002175	0.0568809385349446	0.298075647859087
GO:0001784	phosphotyrosine residue binding	8/1691	47/18639	0.170212765957447	1.87616543150849	0.0589345292366523	0.307517351273301
GO:0004622	lysophospholipase activity	5/1691	24/18639	0.208333333333333	2.29634831460674	0.0606730955847892	0.31374394592151
GO:0005540	hyaluronic acid binding	5/1691	24/18639	0.208333333333333	2.29634831460674	0.0606730955847892	0.31374394592151
GO:0019902	phosphatase binding	24/1691	190/18639	0.126315789473684	1.39231224127735	0.0608987020339049	0.31374394592151
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/1691	17/18639	0.235294117647059	2.59352280237938	0.0617471406295811	0.315452965308446
GO:0008484	sulfuric ester hydrolase activity	4/1691	17/18639	0.235294117647059	2.59352280237938	0.0617471406295811	0.315452965308446
GO:0005496	steroid binding	15/1691	108/18639	0.138888888888889	1.53089887640449	0.063354970438608	0.322318412106418
GO:0051059	NF-kappaB binding	6/1691	32/18639	0.1875	2.06671348314607	0.0648611436022107	0.328550938181338
GO:0019207	kinase regulator activity	34/1691	287/18639	0.118466898954704	1.30579806600634	0.0651182039638687	0.328550938181338
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/1691	40/18639	0.175	1.92893258426966	0.0659716047758643	0.331486952392306
GO:0002020	protease binding	18/1691	136/18639	0.132352941176471	1.4588565763384	0.0665461677754598	0.3330035690731
GO:0001848	complement binding	5/1691	25/18639	0.2	2.20449438202247	0.0704105113478683	0.337597243948624
GO:0008483	transaminase activity	5/1691	25/18639	0.2	2.20449438202247	0.0704105113478683	0.337597243948624
GO:0004016	adenylate cyclase activity	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0005114	type II transforming growth factor beta receptor binding	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0005536	D-glucose binding	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0008503	benzodiazepine receptor activity	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0010854	adenylate cyclase regulator activity	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0019215	intermediate filament binding	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0045294	alpha-catenin binding	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0048185	activin binding	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0070697	activin receptor binding	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	3/1691	11/18639	0.272727272727273	3.00612870275792	0.0707820593373037	0.337597243948624
GO:0031490	chromatin DNA binding	17/1691	128/18639	0.1328125	1.4639220505618	0.0711452234189957	0.338009018656007
GO:0043178	alcohol binding	13/1691	92/18639	0.141304347826087	1.55752320468979	0.0716697662428517	0.33918133559117
GO:0004721	phosphoprotein phosphatase activity	22/1691	175/18639	0.125714285714286	1.38568218298555	0.0732401120479329	0.34310628030892
GO:0017080	sodium channel regulator activity	7/1691	41/18639	0.170731707317073	1.88188544806796	0.0736132769999978	0.34310628030892
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/1691	18/18639	0.222222222222222	2.44943820224719	0.0739041373638379	0.34310628030892
GO:0030228	lipoprotein particle receptor activity	4/1691	18/18639	0.222222222222222	2.44943820224719	0.0739041373638379	0.34310628030892
GO:0098641	cadherin binding involved in cell-cell adhesion	4/1691	18/18639	0.222222222222222	2.44943820224719	0.0739041373638379	0.34310628030892
GO:0004860	protein kinase inhibitor activity	12/1691	84/18639	0.142857142857143	1.57463884430177	0.0761451465031074	0.352171302576872
GO:0019209	kinase activator activity	19/1691	148/18639	0.128378378378378	1.41504706954145	0.0773775091214635	0.356520523159649
GO:0032813	tumor necrosis factor receptor superfamily binding	8/1691	50/18639	0.16	1.76359550561798	0.0794318014173629	0.364609885453384
GO:0043021	ribonucleoprotein complex binding	22/1691	177/18639	0.124293785310734	1.37002475718911	0.0806084004367553	0.366086053306743
GO:0030507	spectrin binding	5/1691	26/18639	0.192307692307692	2.11970613656007	0.0809526899204101	0.366086053306743
GO:0050750	low-density lipoprotein particle receptor binding	5/1691	26/18639	0.192307692307692	2.11970613656007	0.0809526899204101	0.366086053306743
GO:0070006	metalloaminopeptidase activity	5/1691	26/18639	0.192307692307692	2.11970613656007	0.0809526899204101	0.366086053306743
GO:0016247	channel regulator activity	21/1691	168/18639	0.125	1.37780898876405	0.0823656091793831	0.371101139513014
GO:0019887	protein kinase regulator activity	30/1691	255/18639	0.117647058823529	1.29676140118969	0.0846915316240742	0.380177794533068
GO:0043395	heparan sulfate proteoglycan binding	4/1691	19/18639	0.210526315789474	2.32052040212892	0.0871708738032064	0.385108413793205
GO:0070003	threonine-type peptidase activity	4/1691	19/18639	0.210526315789474	2.32052040212892	0.0871708738032064	0.385108413793205
GO:0004859	phospholipase inhibitor activity	3/1691	12/18639	0.25	2.75561797752809	0.0882255311430165	0.385108413793205
GO:0008179	adenylate cyclase binding	3/1691	12/18639	0.25	2.75561797752809	0.0882255311430165	0.385108413793205
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/1691	12/18639	0.25	2.75561797752809	0.0882255311430165	0.385108413793205
GO:0070008	serine-type exopeptidase activity	3/1691	12/18639	0.25	2.75561797752809	0.0882255311430165	0.385108413793205
GO:0070410	co-SMAD binding	3/1691	12/18639	0.25	2.75561797752809	0.0882255311430165	0.385108413793205
GO:0099106	ion channel regulator activity	20/1691	160/18639	0.125	1.37780898876405	0.0883131497642076	0.385108413793205
GO:0098531	ligand-modulated transcription factor activity	9/1691	60/18639	0.15	1.65337078651685	0.0904433037396301	0.390738487149572
GO:0035402	histone H3T11 kinase activity	29/1691	247/18639	0.117408906882591	1.29413637811036	0.0905126934178491	0.390738487149572
GO:0141108	transporter regulator activity	21/1691	170/18639	0.123529411764706	1.36159947124917	0.0905642849003511	0.390738487149572
GO:0023026	MHC class II protein complex binding	5/1691	27/18639	0.185185185185185	2.04119850187266	0.0922830745346158	0.39675223241819
GO:0016829	lyase activity	24/1691	200/18639	0.12	1.32269662921348	0.095902614001027	0.4108669884044
GO:0035401	histone H3Y41 kinase activity	15/1691	115/18639	0.130434782608696	1.43771372740596	0.0969182101750282	0.412324510884005
GO:0140801	histone H2AXY142 kinase activity	15/1691	115/18639	0.130434782608696	1.43771372740596	0.0969182101750282	0.412324510884005
GO:0016505	peptidase activator activity involved in apoptotic process	4/1691	20/18639	0.2	2.20449438202247	0.101497764627685	0.427340588311737
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/1691	20/18639	0.2	2.20449438202247	0.101497764627685	0.427340588311737
GO:0052745	inositol phosphate phosphatase activity	4/1691	20/18639	0.2	2.20449438202247	0.101497764627685	0.427340588311737
GO:0005246	calcium channel regulator activity	8/1691	53/18639	0.150943396226415	1.66376934492262	0.103671028483951	0.433492698094336
GO:0005544	calcium-dependent phospholipid binding	8/1691	53/18639	0.150943396226415	1.66376934492262	0.103671028483951	0.433492698094336
GO:0051019	mitogen-activated protein kinase binding	5/1691	28/18639	0.178571428571429	1.96829855537721	0.10437907718242	0.433492698094336
GO:0051393	alpha-actinin binding	5/1691	28/18639	0.178571428571429	1.96829855537721	0.10437907718242	0.433492698094336
GO:0005096	GTPase activator activity	31/1691	271/18639	0.114391143911439	1.26087317052946	0.10632522052576	0.43366038886067
GO:0008194	UDP-glycosyltransferase activity	18/1691	145/18639	0.124137931034483	1.36830685780705	0.106823721687279	0.43366038886067
GO:0005035	death receptor activity	3/1691	13/18639	0.230769230769231	2.54364736387208	0.107260800520821	0.43366038886067
GO:0005172	vascular endothelial growth factor receptor binding	3/1691	13/18639	0.230769230769231	2.54364736387208	0.107260800520821	0.43366038886067
GO:0061459	L-arginine transmembrane transporter activity	3/1691	13/18639	0.230769230769231	2.54364736387208	0.107260800520821	0.43366038886067
GO:0071837	HMG box domain binding	3/1691	13/18639	0.230769230769231	2.54364736387208	0.107260800520821	0.43366038886067
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/1691	13/18639	0.230769230769231	2.54364736387208	0.107260800520821	0.43366038886067
GO:0140333	glycerophospholipid flippase activity	3/1691	13/18639	0.230769230769231	2.54364736387208	0.107260800520821	0.43366038886067
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	28/1691	243/18639	0.11522633744856	1.27007906783188	0.112352578570689	0.447979360427685
GO:0003925	G protein activity	8/1691	54/18639	0.148148148148148	1.63295880149813	0.112569760043958	0.447979360427685
GO:0050661	NADP binding	8/1691	54/18639	0.148148148148148	1.63295880149813	0.112569760043958	0.447979360427685
GO:0019210	kinase inhibitor activity	12/1691	90/18639	0.133333333333333	1.46966292134831	0.113250819029511	0.447979360427685
GO:0042805	actinin binding	6/1691	37/18639	0.162162162162162	1.78742787731552	0.11395669452018	0.447979360427685
GO:0003712	transcription coregulator activity	53/1691	495/18639	0.107070707070707	1.18018386108274	0.11579734147724	0.447979360427685
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/1691	21/18639	0.19047619047619	2.09951845906902	0.116825744928648	0.447979360427685
GO:0009975	cyclase activity	4/1691	21/18639	0.19047619047619	2.09951845906902	0.116825744928648	0.447979360427685
GO:0019200	carbohydrate kinase activity	4/1691	21/18639	0.19047619047619	2.09951845906902	0.116825744928648	0.447979360427685
GO:0030276	clathrin binding	7/1691	46/18639	0.152173913043478	1.67733268197362	0.119223814190787	0.447979360427685
GO:0004676	3-phosphoinositide-dependent protein kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0004711	ribosomal protein S6 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0035175	histone H3S10 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0035979	histone H2AXS139 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0044022	histone H3S28 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0044023	histone H4S1 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0044024	histone H2AS1 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0044025	histone H2BS14 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0072354	histone H3T3 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0072371	histone H2AS121 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0072518	Rho-dependent protein serine/threonine kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0140823	histone H2BS36 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0140855	histone H3S57 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0140995	histone H2A kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0140997	histone H4 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0140998	histone H2B kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:1990244	histone H2AT120 kinase activity	28/1691	245/18639	0.114285714285714	1.25971107544141	0.120708607355207	0.447979360427685
GO:0004677	DNA-dependent protein kinase activity	28/1691	246/18639	0.113821138211382	1.25459029871198	0.12502764310432	0.461204689517748
GO:0140857	histone H3T45 kinase activity	28/1691	246/18639	0.113821138211382	1.25459029871198	0.12502764310432	0.461204689517748
GO:0030295	protein kinase activator activity	17/1691	139/18639	0.122302158273381	1.34807210411446	0.126347507341509	0.462741915815048
GO:0008331	high voltage-gated calcium channel activity	3/1691	14/18639	0.214285714285714	2.36195826645265	0.127718284708985	0.462741915815048
GO:0032036	myosin heavy chain binding	3/1691	14/18639	0.214285714285714	2.36195826645265	0.127718284708985	0.462741915815048
GO:0044548	S100 protein binding	3/1691	14/18639	0.214285714285714	2.36195826645265	0.127718284708985	0.462741915815048
GO:0046030	inositol trisphosphate phosphatase activity	3/1691	14/18639	0.214285714285714	2.36195826645265	0.127718284708985	0.462741915815048
GO:0071933	Arp2/3 complex binding	3/1691	14/18639	0.214285714285714	2.36195826645265	0.127718284708985	0.462741915815048
GO:0035403	histone H3T6 kinase activity	28/1691	247/18639	0.11336032388664	1.24951098576173	0.129440513383869	0.464089653079485
GO:0008135	translation factor activity, RNA binding	11/1691	83/18639	0.132530120481928	1.46080953025586	0.129531898898269	0.464089653079485
GO:0016798	hydrolase activity, acting on glycosyl bonds	16/1691	130/18639	0.123076923076923	1.35661192739844	0.129711269078384	0.464089653079485
GO:0043495	protein-membrane adaptor activity	7/1691	47/18639	0.148936170212766	1.64164475256993	0.129774439057761	0.464089653079485
GO:0008106	alcohol dehydrogenase (NADP+) activity	5/1691	30/18639	0.166666666666667	1.83707865168539	0.130750893250895	0.464089653079485
GO:0008187	poly-pyrimidine tract binding	5/1691	30/18639	0.166666666666667	1.83707865168539	0.130750893250895	0.464089653079485
GO:0016769	transferase activity, transferring nitrogenous groups	5/1691	30/18639	0.166666666666667	1.83707865168539	0.130750893250895	0.464089653079485
GO:0051082	unfolded protein binding	15/1691	121/18639	0.12396694214876	1.36642213761723	0.133083947254569	0.469654545124314
GO:0008649	rRNA methyltransferase activity	4/1691	22/18639	0.181818181818182	2.00408580183861	0.133088020158077	0.469654545124314
GO:0004679	AMP-activated protein kinase activity	28/1691	248/18639	0.112903225806452	1.24447263501269	0.133946983095483	0.471323534177477
GO:0051219	phosphoprotein binding	12/1691	93/18639	0.129032258064516	1.4222544400145	0.135132514741505	0.474128737067176
GO:0043022	ribosome binding	14/1691	112/18639	0.125	1.37780898876405	0.136436817095385	0.477333391614515
GO:0051117	ATPase binding	11/1691	84/18639	0.130952380952381	1.44341894060995	0.137576478026307	0.47857800475818
GO:0180051	translation factor activity	11/1691	84/18639	0.130952380952381	1.44341894060995	0.137576478026307	0.47857800475818
GO:0003725	double-stranded RNA binding	10/1691	75/18639	0.133333333333333	1.46966292134831	0.13962569328184	0.484326623571382
GO:0017147	Wnt-protein binding	5/1691	31/18639	0.161290322580645	1.77781805001812	0.144956653773193	0.499977610895675
GO:0070273	phosphatidylinositol-4-phosphate binding	5/1691	31/18639	0.161290322580645	1.77781805001812	0.144956653773193	0.499977610895675
GO:0000774	adenyl-nucleotide exchange factor activity	3/1691	15/18639	0.2	2.20449438202247	0.149422256680928	0.502852113041607
GO:0004089	carbonate dehydratase activity	3/1691	15/18639	0.2	2.20449438202247	0.149422256680928	0.502852113041607
GO:0050700	CARD domain binding	3/1691	15/18639	0.2	2.20449438202247	0.149422256680928	0.502852113041607
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/1691	15/18639	0.2	2.20449438202247	0.149422256680928	0.502852113041607
GO:0120283	protein serine/threonine kinase binding	3/1691	15/18639	0.2	2.20449438202247	0.149422256680928	0.502852113041607
GO:0017134	fibroblast growth factor binding	4/1691	23/18639	0.173913043478261	1.91695163654128	0.150211721562718	0.502852113041607
GO:0042171	lysophosphatidic acid acyltransferase activity	4/1691	23/18639	0.173913043478261	1.91695163654128	0.150211721562718	0.502852113041607
GO:0071617	lysophospholipid acyltransferase activity	4/1691	23/18639	0.173913043478261	1.91695163654128	0.150211721562718	0.502852113041607
GO:0140102	catalytic activity, acting on a rRNA	4/1691	23/18639	0.173913043478261	1.91695163654128	0.150211721562718	0.502852113041607
GO:0004177	aminopeptidase activity	6/1691	40/18639	0.15	1.65337078651685	0.150320246732339	0.502852113041607
GO:0071949	FAD binding	6/1691	40/18639	0.15	1.65337078651685	0.150320246732339	0.502852113041607
GO:0060590	ATPase regulator activity	7/1691	49/18639	0.142857142857143	1.57463884430177	0.152205353779395	0.507767040886998
GO:0050660	flavin adenine dinucleotide binding	11/1691	86/18639	0.127906976744186	1.40985105827019	0.154441327514783	0.513822509252179
GO:0051087	protein-folding chaperone binding	16/1691	134/18639	0.119402985074627	1.31611604896864	0.15604122970177	0.517734623548536
GO:0070717	poly-purine tract binding	5/1691	32/18639	0.15625	1.72226123595506	0.159789155656708	0.527304213667138
GO:0120015	sterol transfer activity	5/1691	32/18639	0.15625	1.72226123595506	0.159789155656708	0.527304213667138
GO:1990841	promoter-specific chromatin binding	9/1691	68/18639	0.132352941176471	1.4588565763384	0.160623820109528	0.528629876964243
GO:0004879	nuclear receptor activity	8/1691	59/18639	0.135593220338983	1.49457246238812	0.162866949331546	0.533138190707285
GO:0045309	protein phosphorylated amino acid binding	8/1691	59/18639	0.135593220338983	1.49457246238812	0.162866949331546	0.533138190707285
GO:0048027	mRNA 5'-UTR binding	4/1691	24/18639	0.166666666666667	1.83707865168539	0.168119446758303	0.547396918645035
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/1691	24/18639	0.166666666666667	1.83707865168539	0.168119446758303	0.547396918645035
GO:0002039	p53 binding	9/1691	69/18639	0.130434782608696	1.43771372740596	0.170858188084242	0.547527899305741
GO:0005024	transforming growth factor beta receptor activity	3/1691	16/18639	0.1875	2.06671348314607	0.172195506415565	0.547527899305741
GO:0005149	interleukin-1 receptor binding	3/1691	16/18639	0.1875	2.06671348314607	0.172195506415565	0.547527899305741
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/1691	16/18639	0.1875	2.06671348314607	0.172195506415565	0.547527899305741
GO:0015385	sodium:proton antiporter activity	3/1691	16/18639	0.1875	2.06671348314607	0.172195506415565	0.547527899305741
GO:0015923	mannosidase activity	3/1691	16/18639	0.1875	2.06671348314607	0.172195506415565	0.547527899305741
GO:0055102	lipase inhibitor activity	3/1691	16/18639	0.1875	2.06671348314607	0.172195506415565	0.547527899305741
GO:0140327	flippase activity	3/1691	16/18639	0.1875	2.06671348314607	0.172195506415565	0.547527899305741
GO:0140328	floppase activity	3/1691	16/18639	0.1875	2.06671348314607	0.172195506415565	0.547527899305741
GO:0016835	carbon-oxygen lyase activity	10/1691	79/18639	0.126582278481013	1.39524960887498	0.176933726399918	0.55728353901647
GO:0033293	monocarboxylic acid binding	10/1691	79/18639	0.126582278481013	1.39524960887498	0.176933726399918	0.55728353901647
GO:0008307	structural constituent of muscle	6/1691	42/18639	0.142857142857143	1.57463884430177	0.177089281849624	0.55728353901647
GO:0035198	miRNA binding	6/1691	42/18639	0.142857142857143	1.57463884430177	0.177089281849624	0.55728353901647
GO:0016836	hydro-lyase activity	8/1691	61/18639	0.131147540983607	1.44557008657211	0.18548011977395	0.580147967390551
GO:0005251	delayed rectifier potassium channel activity	4/1691	25/18639	0.16	1.76359550561798	0.186730672550767	0.580147967390551
GO:0005537	D-mannose binding	4/1691	25/18639	0.16	1.76359550561798	0.186730672550767	0.580147967390551
GO:0015271	outward rectifier potassium channel activity	4/1691	25/18639	0.16	1.76359550561798	0.186730672550767	0.580147967390551
GO:0120020	cholesterol transfer activity	4/1691	25/18639	0.16	1.76359550561798	0.186730672550767	0.580147967390551
GO:0046943	carboxylic acid transmembrane transporter activity	21/1691	188/18639	0.111702127659574	1.23123356442744	0.187362333197456	0.580633017345416
GO:0030159	signaling receptor complex adaptor activity	7/1691	52/18639	0.134615384615385	1.48379429559205	0.188913084007824	0.583956647021653
GO:0005342	organic acid transmembrane transporter activity	21/1691	189/18639	0.111111111111111	1.2247191011236	0.193904029677503	0.593421189390592
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/1691	17/18639	0.176470588235294	1.94514210178453	0.195863013369704	0.593421189390592
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/1691	17/18639	0.176470588235294	1.94514210178453	0.195863013369704	0.593421189390592
GO:0030169	low-density lipoprotein particle binding	3/1691	17/18639	0.176470588235294	1.94514210178453	0.195863013369704	0.593421189390592
GO:0031489	myosin V binding	3/1691	17/18639	0.176470588235294	1.94514210178453	0.195863013369704	0.593421189390592
GO:0045236	CXCR chemokine receptor binding	3/1691	17/18639	0.176470588235294	1.94514210178453	0.195863013369704	0.593421189390592
GO:0070492	oligosaccharide binding	3/1691	17/18639	0.176470588235294	1.94514210178453	0.195863013369704	0.593421189390592
GO:1990226	histone methyltransferase binding	3/1691	17/18639	0.176470588235294	1.94514210178453	0.195863013369704	0.593421189390592
GO:0042379	chemokine receptor binding	9/1691	72/18639	0.125	1.37780898876405	0.20327488136679	0.614353044922896
GO:0030020	extracellular matrix structural constituent conferring tensile strength	6/1691	44/18639	0.136363636363636	1.50306435137896	0.205615568498567	0.616374665020651
GO:0008143	poly(A) binding	4/1691	26/18639	0.153846153846154	1.69576490924806	0.205963033029014	0.616374665020651
GO:0030247	polysaccharide binding	4/1691	26/18639	0.153846153846154	1.69576490924806	0.205963033029014	0.616374665020651
GO:0052742	phosphatidylinositol kinase activity	4/1691	26/18639	0.153846153846154	1.69576490924806	0.205963033029014	0.616374665020651
GO:0005154	epidermal growth factor receptor binding	5/1691	35/18639	0.142857142857143	1.57463884430177	0.207597516217444	0.619747108316624
GO:0008238	exopeptidase activity	12/1691	102/18639	0.117647058823529	1.29676140118969	0.21303510826176	0.634428944360022
GO:0051287	NAD binding	7/1691	54/18639	0.12962962962963	1.42883895131086	0.215186926424285	0.639029259117962
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	10/1691	83/18639	0.120481927710843	1.32800866386896	0.218333332747094	0.639029259117962
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	3/1691	18/18639	0.166666666666667	1.83707865168539	0.220254788570877	0.639029259117962
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/1691	18/18639	0.166666666666667	1.83707865168539	0.220254788570877	0.639029259117962
GO:0031690	adrenergic receptor binding	3/1691	18/18639	0.166666666666667	1.83707865168539	0.220254788570877	0.639029259117962
GO:0034185	apolipoprotein binding	3/1691	18/18639	0.166666666666667	1.83707865168539	0.220254788570877	0.639029259117962
GO:1901611	phosphatidylglycerol binding	3/1691	18/18639	0.166666666666667	1.83707865168539	0.220254788570877	0.639029259117962
GO:0004722	protein serine/threonine phosphatase activity	12/1691	103/18639	0.116504854368932	1.28417148467328	0.222701771862075	0.639029259117962
GO:0044390	ubiquitin-like protein conjugating enzyme binding	5/1691	36/18639	0.138888888888889	1.53089887640449	0.224477461314356	0.639029259117962
GO:0004364	glutathione transferase activity	4/1691	27/18639	0.148148148148148	1.63295880149813	0.225733460593257	0.639029259117962
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/1691	27/18639	0.148148148148148	1.63295880149813	0.225733460593257	0.639029259117962
GO:0008266	poly(U) RNA binding	4/1691	27/18639	0.148148148148148	1.63295880149813	0.225733460593257	0.639029259117962
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/1691	27/18639	0.148148148148148	1.63295880149813	0.225733460593257	0.639029259117962
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0005031	tumor necrosis factor receptor activity	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0005381	iron ion transmembrane transporter activity	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0015203	polyamine transmembrane transporter activity	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0019911	structural constituent of myelin sheath	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0043208	glycosphingolipid binding	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0070513	death domain binding	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0097177	mitochondrial ribosome binding	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0140135	mechanosensitive monoatomic cation channel activity	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:1905394	retromer complex binding	2/1691	10/18639	0.2	2.20449438202247	0.22818735215023	0.639029259117962
GO:0140313	molecular sequestering activity	7/1691	55/18639	0.127272727272727	1.40286006128703	0.228795940305279	0.63926737554404
GO:0019903	protein phosphatase binding	16/1691	144/18639	0.111111111111111	1.2247191011236	0.232931004188666	0.64933505962183
GO:0120013	lipid transfer activity	8/1691	65/18639	0.123076923076923	1.35661192739844	0.234323778950841	0.651729690430473
GO:0030291	protein serine/threonine kinase inhibitor activity	6/1691	46/18639	0.130434782608696	1.43771372740596	0.235643854636864	0.653911696617298
GO:0023023	MHC protein complex binding	5/1691	37/18639	0.135135135135135	1.48952323109626	0.241746331125946	0.667369272018826
GO:0030170	pyridoxal phosphate binding	7/1691	56/18639	0.125	1.37780898876405	0.242687172616577	0.667369272018826
GO:0170055	lipid transmembrane transporter activity	7/1691	56/18639	0.125	1.37780898876405	0.242687172616577	0.667369272018826
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/1691	19/18639	0.157894736842105	1.74039030159669	0.245208022589815	0.667369272018826
GO:0015245	fatty acid transmembrane transporter activity	3/1691	19/18639	0.157894736842105	1.74039030159669	0.245208022589815	0.667369272018826
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/1691	19/18639	0.157894736842105	1.74039030159669	0.245208022589815	0.667369272018826
GO:0030506	ankyrin binding	3/1691	19/18639	0.157894736842105	1.74039030159669	0.245208022589815	0.667369272018826
GO:0050145	nucleoside monophosphate kinase activity	3/1691	19/18639	0.157894736842105	1.74039030159669	0.245208022589815	0.667369272018826
GO:0046875	ephrin receptor binding	4/1691	28/18639	0.142857142857143	1.57463884430177	0.24595919116173	0.667369272018826
GO:0097718	disordered domain specific binding	4/1691	28/18639	0.142857142857143	1.57463884430177	0.24595919116173	0.667369272018826
GO:0140375	immune receptor activity	17/1691	156/18639	0.108974358974359	1.20116681071737	0.248729023794791	0.673388332712727
GO:0016209	antioxidant activity	10/1691	86/18639	0.116279069767442	1.28168278024562	0.251667082413214	0.679336278559561
GO:0004601	peroxidase activity	7/1691	57/18639	0.12280701754386	1.35363690124187	0.256835463366619	0.679336278559561
GO:0070279	vitamin B6 binding	7/1691	57/18639	0.12280701754386	1.35363690124187	0.256835463366619	0.679336278559561
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	8/1691	67/18639	0.119402985074627	1.31611604896864	0.260268597114037	0.679336278559561
GO:0019208	phosphatase regulator activity	13/1691	117/18639	0.111111111111111	1.2247191011236	0.262325259312517	0.679336278559561
GO:0019888	protein phosphatase regulator activity	12/1691	107/18639	0.11214953271028	1.23616507403129	0.263038155190676	0.679336278559561
GO:0008081	phosphoric diester hydrolase activity	10/1691	87/18639	0.114942528735632	1.26695079426579	0.263149756035825	0.679336278559561
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0002162	dystroglycan binding	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0005225	volume-sensitive anion channel activity	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0008432	JUN kinase binding	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0047676	arachidonate-CoA ligase activity	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0050786	RAGE receptor binding	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0050998	nitric-oxide synthase binding	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0140031	phosphorylation-dependent protein binding	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:1990948	ubiquitin ligase inhibitor activity	2/1691	11/18639	0.181818181818182	2.00408580183861	0.263166306108659	0.679336278559561
GO:0035250	UDP-galactosyltransferase activity	4/1691	29/18639	0.137931034482759	1.52034095311895	0.266558637501944	0.683756505020743
GO:0043236	laminin binding	4/1691	29/18639	0.137931034482759	1.52034095311895	0.266558637501944	0.683756505020743
GO:0106222	lncRNA binding	4/1691	29/18639	0.137931034482759	1.52034095311895	0.266558637501944	0.683756505020743
GO:0010851	cyclase regulator activity	3/1691	20/18639	0.15	1.65337078651685	0.270568656347838	0.688259019584814
GO:0015095	magnesium ion transmembrane transporter activity	3/1691	20/18639	0.15	1.65337078651685	0.270568656347838	0.688259019584814
GO:0030742	GTP-dependent protein binding	3/1691	20/18639	0.15	1.65337078651685	0.270568656347838	0.688259019584814
GO:0042288	MHC class I protein binding	3/1691	20/18639	0.15	1.65337078651685	0.270568656347838	0.688259019584814
GO:0061980	regulatory RNA binding	7/1691	58/18639	0.120689655172414	1.33029833397908	0.271215218996008	0.688469402066789
GO:0030145	manganese ion binding	8/1691	68/18639	0.117647058823529	1.29676140118969	0.273554567381305	0.692967067992892
GO:0035254	glutamate receptor binding	6/1691	49/18639	0.122448979591837	1.34969043797294	0.28290747742678	0.708261861877981
GO:0004620	phospholipase activity	12/1691	109/18639	0.110091743119266	1.21348314606742	0.284084241342615	0.708261861877981
GO:0015459	potassium channel regulator activity	7/1691	59/18639	0.11864406779661	1.3077509045896	0.285800562989301	0.708261861877981
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/1691	59/18639	0.11864406779661	1.3077509045896	0.285800562989301	0.708261861877981
GO:0001965	G-protein alpha-subunit binding	4/1691	30/18639	0.133333333333333	1.46966292134831	0.28745213661749	0.708261861877981
GO:0031624	ubiquitin conjugating enzyme binding	4/1691	30/18639	0.133333333333333	1.46966292134831	0.28745213661749	0.708261861877981
GO:0033612	receptor serine/threonine kinase binding	4/1691	30/18639	0.133333333333333	1.46966292134831	0.28745213661749	0.708261861877981
GO:0030331	nuclear estrogen receptor binding	5/1691	40/18639	0.125	1.37780898876405	0.295381042873857	0.708261861877981
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	5/1691	40/18639	0.125	1.37780898876405	0.295381042873857	0.708261861877981
GO:0061791	GTPase motor activity	5/1691	40/18639	0.125	1.37780898876405	0.295381042873857	0.708261861877981
GO:1990606	membrane scission GTPase motor activity	5/1691	40/18639	0.125	1.37780898876405	0.295381042873857	0.708261861877981
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/1691	21/18639	0.142857142857143	1.57463884430177	0.296192474917704	0.708261861877981
GO:0001846	opsonin binding	3/1691	21/18639	0.142857142857143	1.57463884430177	0.296192474917704	0.708261861877981
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/1691	21/18639	0.142857142857143	1.57463884430177	0.296192474917704	0.708261861877981
GO:0015174	basic amino acid transmembrane transporter activity	3/1691	21/18639	0.142857142857143	1.57463884430177	0.296192474917704	0.708261861877981
GO:0004032	aldose reductase (NADPH) activity	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0005025	transforming growth factor beta receptor activity, type I	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0005026	transforming growth factor beta receptor activity, type II	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0005078	MAP-kinase scaffold activity	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0016361	activin receptor activity, type I	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0016362	activin receptor activity, type II	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0016801	hydrolase activity, acting on ether bonds	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0016803	ether hydrolase activity	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0017002	activin receptor activity	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0035251	UDP-glucosyltransferase activity	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0035497	cAMP response element binding	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0140829	bicarbonate:monoatomic anion antiporter activity	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0140900	chloride:bicarbonate antiporter activity	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:1990459	transferrin receptor binding	2/1691	12/18639	0.166666666666667	1.83707865168539	0.298154461101787	0.708261861877981
GO:0048020	CCR chemokine receptor binding	6/1691	50/18639	0.12	1.32269662921348	0.299115013738524	0.709163945193665
GO:0016782	transferase activity, transferring sulphur-containing groups	8/1691	70/18639	0.114285714285714	1.25971107544141	0.30065349200837	0.7114300653919
GO:0005244	voltage-gated monoatomic ion channel activity	18/1691	173/18639	0.104046242774566	1.14684678833539	0.306007114565232	0.719981514103647
GO:0016411	acylglycerol O-acyltransferase activity	4/1691	31/18639	0.129032258064516	1.4222544400145	0.308562578520349	0.719981514103647
GO:0047499	calcium-independent phospholipase A2 activity	4/1691	31/18639	0.129032258064516	1.4222544400145	0.308562578520349	0.719981514103647
GO:0033192	calmodulin-dependent protein phosphatase activity	9/1691	81/18639	0.111111111111111	1.2247191011236	0.312717414898254	0.719981514103647
GO:0140791	histone H2AXS140 phosphatase activity	9/1691	81/18639	0.111111111111111	1.2247191011236	0.312717414898254	0.719981514103647
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	9/1691	81/18639	0.111111111111111	1.2247191011236	0.312717414898254	0.719981514103647
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	9/1691	81/18639	0.111111111111111	1.2247191011236	0.312717414898254	0.719981514103647
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	9/1691	81/18639	0.111111111111111	1.2247191011236	0.312717414898254	0.719981514103647
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	9/1691	81/18639	0.111111111111111	1.2247191011236	0.312717414898254	0.719981514103647
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	9/1691	81/18639	0.111111111111111	1.2247191011236	0.312717414898254	0.719981514103647
GO:1990439	MAP kinase serine/threonine phosphatase activity	9/1691	81/18639	0.111111111111111	1.2247191011236	0.312717414898254	0.719981514103647
GO:0001530	lipopolysaccharide binding	5/1691	41/18639	0.121951219512195	1.34420389147712	0.313702019249091	0.719981514103647
GO:0001727	lipid kinase activity	5/1691	41/18639	0.121951219512195	1.34420389147712	0.313702019249091	0.719981514103647
GO:0042287	MHC protein binding	5/1691	41/18639	0.121951219512195	1.34420389147712	0.313702019249091	0.719981514103647
GO:0140318	protein transporter activity	5/1691	41/18639	0.121951219512195	1.34420389147712	0.313702019249091	0.719981514103647
GO:0140828	metal cation:monoatomic cation antiporter activity	5/1691	41/18639	0.121951219512195	1.34420389147712	0.313702019249091	0.719981514103647
GO:0016830	carbon-carbon lyase activity	6/1691	51/18639	0.117647058823529	1.29676140118969	0.315491018294009	0.722728955604099
GO:0008514	organic anion transmembrane transporter activity	27/1691	269/18639	0.100371747211896	1.10634476421202	0.318988634003424	0.729305814217392
GO:0015171	amino acid transmembrane transporter activity	11/1691	102/18639	0.107843137254902	1.18869795109055	0.31969638395166	0.729305814217392
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	3/1691	22/18639	0.136363636363636	1.50306435137896	0.321945809879749	0.729305814217392
GO:0031683	G-protein beta/gamma-subunit complex binding	3/1691	22/18639	0.136363636363636	1.50306435137896	0.321945809879749	0.729305814217392
GO:0061133	endopeptidase activator activity	3/1691	22/18639	0.136363636363636	1.50306435137896	0.321945809879749	0.729305814217392
GO:0140517	protein-RNA adaptor activity	3/1691	22/18639	0.136363636363636	1.50306435137896	0.321945809879749	0.729305814217392
GO:0022832	voltage-gated channel activity	18/1691	175/18639	0.102857142857143	1.13373996789727	0.3234960111847	0.730980197219887
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	9/1691	82/18639	0.109756097560976	1.20978350232941	0.325672859429251	0.730980197219887
GO:0033549	MAP kinase phosphatase activity	9/1691	82/18639	0.109756097560976	1.20978350232941	0.325672859429251	0.730980197219887
GO:0030515	snoRNA binding	4/1691	32/18639	0.125	1.37780898876405	0.329815924643727	0.730980197219887
GO:0031369	translation initiation factor binding	4/1691	32/18639	0.125	1.37780898876405	0.329815924643727	0.730980197219887
GO:0071813	lipoprotein particle binding	4/1691	32/18639	0.125	1.37780898876405	0.329815924643727	0.730980197219887
GO:0071814	protein-lipid complex binding	4/1691	32/18639	0.125	1.37780898876405	0.329815924643727	0.730980197219887
GO:0004993	G protein-coupled serotonin receptor activity	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0017154	semaphorin receptor activity	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0039706	co-receptor binding	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0045159	myosin II binding	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0046974	histone H3K9 methyltransferase activity	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0070123	transforming growth factor beta receptor activity, type III	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0071714	icosanoid transmembrane transporter activity	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0097157	pre-mRNA intronic binding	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0140852	histone ubiquitin ligase activity	2/1691	13/18639	0.153846153846154	1.69576490924806	0.332862399389236	0.730980197219887
GO:0031406	carboxylic acid binding	19/1691	187/18639	0.101604278074866	1.11993030102746	0.336714084597078	0.73811112619934
GO:0015297	antiporter activity	14/1691	135/18639	0.103703703703704	1.14307116104869	0.340496420997666	0.745064749172313
GO:0005507	copper ion binding	7/1691	63/18639	0.111111111111111	1.2247191011236	0.345678251146408	0.749552314253872
GO:0022824	transmitter-gated monoatomic ion channel activity	7/1691	63/18639	0.111111111111111	1.2247191011236	0.345678251146408	0.749552314253872
GO:0022835	transmitter-gated channel activity	7/1691	63/18639	0.111111111111111	1.2247191011236	0.345678251146408	0.749552314253872
GO:0031681	G-protein beta-subunit binding	3/1691	23/18639	0.130434782608696	1.43771372740596	0.347705923127305	0.749552314253872
GO:0043274	phospholipase binding	3/1691	23/18639	0.130434782608696	1.43771372740596	0.347705923127305	0.749552314253872
GO:0008146	sulfotransferase activity	6/1691	53/18639	0.113207547169811	1.24782700869197	0.348611798420739	0.749552314253872
GO:0016860	intramolecular oxidoreductase activity	6/1691	53/18639	0.113207547169811	1.24782700869197	0.348611798420739	0.749552314253872
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	6/1691	53/18639	0.113207547169811	1.24782700869197	0.348611798420739	0.749552314253872
GO:0004712	protein serine/threonine/tyrosine kinase activity	5/1691	43/18639	0.116279069767442	1.28168278024562	0.350717798693607	0.749552314253872
GO:0008200	ion channel inhibitor activity	5/1691	43/18639	0.116279069767442	1.28168278024562	0.350717798693607	0.749552314253872
GO:0008375	acetylglucosaminyltransferase activity	5/1691	43/18639	0.116279069767442	1.28168278024562	0.350717798693607	0.749552314253872
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/1691	33/18639	0.121212121212121	1.33605720122574	0.351141624695508	0.749552314253872
GO:0030296	protein tyrosine kinase activator activity	4/1691	33/18639	0.121212121212121	1.33605720122574	0.351141624695508	0.749552314253872
GO:0140311	protein sequestering activity	4/1691	33/18639	0.121212121212121	1.33605720122574	0.351141624695508	0.749552314253872
GO:0017018	myosin phosphatase activity	9/1691	84/18639	0.107142857142857	1.18097913322632	0.351865416189099	0.749786515125462
GO:0043177	organic acid binding	19/1691	189/18639	0.100529100529101	1.10807918673087	0.354103614915677	0.753241313261396
GO:0030695	GTPase regulator activity	47/1691	489/18639	0.0961145194274029	1.0594195905425	0.359816427801688	0.758018084826808
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	6/1691	54/18639	0.111111111111111	1.2247191011236	0.365289907420296	0.758018084826808
GO:0140463	chromatin-protein adaptor activity	6/1691	54/18639	0.111111111111111	1.2247191011236	0.365289907420296	0.758018084826808
GO:0060589	nucleoside-triphosphatase regulator activity	47/1691	490/18639	0.0959183673469388	1.05725750974547	0.365296726952196	0.758018084826808
GO:0004065	arylsulfatase activity	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0004705	JUN kinase activity	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0005161	platelet-derived growth factor receptor binding	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0005545	1-phosphatidylinositol binding	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0008494	translation activator activity	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0008559	ABC-type xenobiotic transporter activity	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0042813	Wnt receptor activity	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0070742	C2H2 zinc finger domain binding	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0098821	BMP receptor activity	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:1901474	azole transmembrane transporter activity	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:1901612	cardiolipin binding	2/1691	14/18639	0.142857142857143	1.57463884430177	0.367053085169277	0.758018084826808
GO:0001046	core promoter sequence-specific DNA binding	5/1691	44/18639	0.113636363636364	1.25255362614913	0.369320648718612	0.758018084826808
GO:0016248	channel inhibitor activity	5/1691	44/18639	0.113636363636364	1.25255362614913	0.369320648718612	0.758018084826808
GO:0030547	signaling receptor inhibitor activity	5/1691	44/18639	0.113636363636364	1.25255362614913	0.369320648718612	0.758018084826808
GO:0008017	microtubule binding	27/1691	276/18639	0.0978260869565217	1.07828529555447	0.3693863722129	0.758018084826808
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/1691	34/18639	0.117647058823529	1.29676140118969	0.372472940996362	0.75852569826851
GO:0090482	vitamin transmembrane transporter activity	4/1691	34/18639	0.117647058823529	1.29676140118969	0.372472940996362	0.75852569826851
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/1691	24/18639	0.125	1.37780898876405	0.373361134037162	0.75852569826851
GO:0050699	WW domain binding	3/1691	24/18639	0.125	1.37780898876405	0.373361134037162	0.75852569826851
GO:0060229	lipase activator activity	3/1691	24/18639	0.125	1.37780898876405	0.373361134037162	0.75852569826851
GO:0070300	phosphatidic acid binding	3/1691	24/18639	0.125	1.37780898876405	0.373361134037162	0.75852569826851
GO:0030594	neurotransmitter receptor activity	10/1691	97/18639	0.103092783505155	1.13633731032086	0.384801707935493	0.780469909284447
GO:0141110	transporter inhibitor activity	5/1691	45/18639	0.111111111111111	1.2247191011236	0.387928400812191	0.78550676184359
GO:0004623	phospholipase A2 activity	4/1691	35/18639	0.114285714285714	1.25971107544141	0.393747189354932	0.790069355543741
GO:0005249	voltage-gated potassium channel activity	10/1691	98/18639	0.102040816326531	1.12474203164412	0.397351007123714	0.790069355543741
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	6/1691	56/18639	0.107142857142857	1.18097913322632	0.398721408229659	0.790069355543741
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/1691	25/18639	0.12	1.32269662921348	0.39881074242167	0.790069355543741
GO:0019211	phosphatase activator activity	3/1691	25/18639	0.12	1.32269662921348	0.39881074242167	0.790069355543741
GO:0016298	lipase activity	13/1691	130/18639	0.1	1.10224719101124	0.399141630062035	0.790069355543741
GO:0004467	long-chain fatty acid-CoA ligase activity	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0004559	alpha-mannosidase activity	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0008242	omega peptidase activity	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0033130	acetylcholine receptor binding	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0051371	muscle alpha-actinin binding	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0141050	histone H3K deacetylase activity	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0141051	histone H4K deacetylase activity	2/1691	15/18639	0.133333333333333	1.46966292134831	0.400534751090561	0.790069355543741
GO:0004180	carboxypeptidase activity	5/1691	46/18639	0.108695652173913	1.1980947728383	0.406499686931133	0.800542125391796
GO:0004190	aspartic-type endopeptidase activity	4/1691	36/18639	0.111111111111111	1.2247191011236	0.414905905360005	0.81415784609372
GO:0055106	ubiquitin-protein transferase regulator activity	4/1691	36/18639	0.111111111111111	1.2247191011236	0.414905905360005	0.81415784609372
GO:0015932	nucleobase-containing compound transmembrane transporter activity	6/1691	57/18639	0.105263157894737	1.16026020106446	0.415413872331194	0.81415784609372
GO:0022843	voltage-gated monoatomic cation channel activity	14/1691	143/18639	0.0979020979020979	1.07912312406694	0.423764098367274	0.824990783411764
GO:0004435	phosphatidylinositol phospholipase C activity	3/1691	26/18639	0.115384615384615	1.27182368193604	0.423964791472886	0.824990783411764
GO:0050681	nuclear androgen receptor binding	3/1691	26/18639	0.115384615384615	1.27182368193604	0.423964791472886	0.824990783411764
GO:0051139	metal cation:proton antiporter activity	3/1691	26/18639	0.115384615384615	1.27182368193604	0.423964791472886	0.824990783411764
GO:0005504	fatty acid binding	5/1691	47/18639	0.106382978723404	1.1726033946928	0.424995252060606	0.824990783411764
GO:0140359	ABC-type transporter activity	5/1691	47/18639	0.106382978723404	1.1726033946928	0.424995252060606	0.824990783411764
GO:0000062	fatty-acyl-CoA binding	2/1691	16/18639	0.125	1.37780898876405	0.433154643186989	0.828968368857859
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/1691	16/18639	0.125	1.37780898876405	0.433154643186989	0.828968368857859
GO:0004707	MAP kinase activity	2/1691	16/18639	0.125	1.37780898876405	0.433154643186989	0.828968368857859
GO:0004708	MAP kinase kinase activity	2/1691	16/18639	0.125	1.37780898876405	0.433154643186989	0.828968368857859
GO:0005159	insulin-like growth factor receptor binding	2/1691	16/18639	0.125	1.37780898876405	0.433154643186989	0.828968368857859
GO:0005521	lamin binding	2/1691	16/18639	0.125	1.37780898876405	0.433154643186989	0.828968368857859
GO:0016722	oxidoreductase activity, acting on metal ions	2/1691	16/18639	0.125	1.37780898876405	0.433154643186989	0.828968368857859
GO:0022841	potassium ion leak channel activity	2/1691	16/18639	0.125	1.37780898876405	0.433154643186989	0.828968368857859
GO:0030275	LRR domain binding	2/1691	16/18639	0.125	1.37780898876405	0.433154643186989	0.828968368857859
GO:0019213	deacetylase activity	4/1691	37/18639	0.108108108108108	1.19161858487701	0.435894944661103	0.83160582411126
GO:0070001	aspartic-type peptidase activity	4/1691	37/18639	0.108108108108108	1.19161858487701	0.435894944661103	0.83160582411126
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	16/1691	167/18639	0.0958083832335329	1.0560452129449	0.448064843918164	0.849482274827748
GO:0001671	ATPase activator activity	3/1691	27/18639	0.111111111111111	1.2247191011236	0.44874370783284	0.849482274827748
GO:0016405	CoA-ligase activity	3/1691	27/18639	0.111111111111111	1.2247191011236	0.44874370783284	0.849482274827748
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/1691	27/18639	0.111111111111111	1.2247191011236	0.44874370783284	0.849482274827748
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/1691	27/18639	0.111111111111111	1.2247191011236	0.44874370783284	0.849482274827748
GO:0015631	tubulin binding	36/1691	385/18639	0.0935064935064935	1.03067269808843	0.450001160660408	0.850543989421606
GO:0005267	potassium channel activity	12/1691	124/18639	0.0967741935483871	1.06669083001087	0.451945385241418	0.852660695111545
GO:0008028	monocarboxylic acid transmembrane transporter activity	7/1691	70/18639	0.1	1.10224719101124	0.452517715341753	0.852660695111545
GO:0015101	organic cation transmembrane transporter activity	8/1691	81/18639	0.0987654320987654	1.08863920099875	0.455573706999408	0.857096296219226
GO:0043531	ADP binding	4/1691	38/18639	0.105263157894737	1.16026020106446	0.456664525401613	0.857826746946721
GO:0005253	monoatomic anion channel activity	10/1691	103/18639	0.0970873786407767	1.0701429038944	0.46008694963904	0.861562017675293
GO:0016763	pentosyltransferase activity	5/1691	49/18639	0.102040816326531	1.12474203164412	0.461613349333852	0.861562017675293
GO:0036041	long-chain fatty acid binding	2/1691	17/18639	0.117647058823529	1.29676140118969	0.464793527162628	0.861562017675293
GO:0046965	nuclear retinoid X receptor binding	2/1691	17/18639	0.117647058823529	1.29676140118969	0.464793527162628	0.861562017675293
GO:0048038	quinone binding	2/1691	17/18639	0.117647058823529	1.29676140118969	0.464793527162628	0.861562017675293
GO:0051787	misfolded protein binding	2/1691	17/18639	0.117647058823529	1.29676140118969	0.464793527162628	0.861562017675293
GO:0070403	NAD+ binding	2/1691	17/18639	0.117647058823529	1.29676140118969	0.464793527162628	0.861562017675293
GO:1901567	fatty acid derivative binding	2/1691	17/18639	0.117647058823529	1.29676140118969	0.464793527162628	0.861562017675293
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	6/1691	60/18639	0.1	1.10224719101124	0.465058241274962	0.861562017675293
GO:0015085	calcium ion transmembrane transporter activity	14/1691	147/18639	0.0952380952380952	1.04975922953451	0.465709198743402	0.861562017675293
GO:0140658	ATP-dependent chromatin remodeler activity	15/1691	158/18639	0.0949367088607595	1.04643720665624	0.466709922011947	0.862107132793627
GO:0046625	sphingolipid binding	3/1691	28/18639	0.107142857142857	1.18097913322632	0.473077849833374	0.869921769046008
GO:0050698	proteoglycan sulfotransferase activity	3/1691	28/18639	0.107142857142857	1.18097913322632	0.473077849833374	0.869921769046008
GO:0141052	histone H3 demethylase activity	3/1691	28/18639	0.107142857142857	1.18097913322632	0.473077849833374	0.869921769046008
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/1691	39/18639	0.102564102564103	1.1305099394987	0.47716922049252	0.876125741686267
GO:0015605	organophosphate ester transmembrane transporter activity	5/1691	50/18639	0.1	1.10224719101124	0.479668719955555	0.87939265325185
GO:0008308	voltage-gated monoatomic anion channel activity	2/1691	18/18639	0.111111111111111	1.2247191011236	0.495360869486596	0.89468808761645
GO:0008525	phosphatidylcholine transporter activity	2/1691	18/18639	0.111111111111111	1.2247191011236	0.495360869486596	0.89468808761645
GO:0017075	syntaxin-1 binding	2/1691	18/18639	0.111111111111111	1.2247191011236	0.495360869486596	0.89468808761645
GO:0022851	GABA-gated chloride ion channel activity	2/1691	18/18639	0.111111111111111	1.2247191011236	0.495360869486596	0.89468808761645
GO:0070064	proline-rich region binding	2/1691	18/18639	0.111111111111111	1.2247191011236	0.495360869486596	0.89468808761645
GO:0070628	proteasome binding	2/1691	18/18639	0.111111111111111	1.2247191011236	0.495360869486596	0.89468808761645
GO:0004629	phospholipase C activity	3/1691	29/18639	0.103448275862069	1.14025571483921	0.496906989717769	0.89468808761645
GO:0099604	ligand-gated calcium channel activity	3/1691	29/18639	0.103448275862069	1.14025571483921	0.496906989717769	0.89468808761645
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	12/1691	128/18639	0.09375	1.03335674157303	0.497103839224139	0.89468808761645
GO:0015036	disulfide oxidoreductase activity	4/1691	40/18639	0.1	1.10224719101124	0.497367906894594	0.89468808761645
GO:0015144	carbohydrate transmembrane transporter activity	4/1691	40/18639	0.1	1.10224719101124	0.497367906894594	0.89468808761645
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	7/1691	73/18639	0.0958904109589041	1.05694936124365	0.497504431558015	0.89468808761645
GO:0015179	L-amino acid transmembrane transporter activity	6/1691	62/18639	0.0967741935483871	1.06669083001087	0.497537437749033	0.89468808761645
GO:0140674	ATP-dependent histone chaperone activity	14/1691	152/18639	0.0921052631578947	1.0152276759314	0.517512816278077	0.91932473795723
GO:0015215	nucleotide transmembrane transporter activity	3/1691	30/18639	0.1	1.10224719101124	0.520179751173355	0.91932473795723
GO:0032452	histone demethylase activity	3/1691	30/18639	0.1	1.10224719101124	0.520179751173355	0.91932473795723
GO:0003756	protein disulfide isomerase activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0004890	GABA-A receptor activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0005229	intracellularly calcium-gated chloride channel activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0008381	mechanosensitive monoatomic ion channel activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0016918	retinal binding	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0022840	leak channel activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0022842	narrow pore channel activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0031420	alkali metal ion binding	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0042800	histone H3K4 methyltransferase activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0046527	glucosyltransferase activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0099589	serotonin receptor activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0120227	acyl-CoA binding	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0141147	intracellularly calcium-gated channel activity	2/1691	19/18639	0.105263157894737	1.16026020106446	0.524790616180336	0.91932473795723
GO:0031072	heat shock protein binding	12/1691	131/18639	0.0916030534351145	1.00969208336907	0.530388987235684	0.927800792857836
GO:1901505	carbohydrate derivative transmembrane transporter activity	5/1691	53/18639	0.0943396226415094	1.03985584057664	0.532466682089638	0.930102745109368
GO:0008170	N-methyltransferase activity	9/1691	98/18639	0.0918367346938776	1.01226782847971	0.535862918189412	0.933364654934767
GO:0042626	ATPase-coupled transmembrane transporter activity	9/1691	98/18639	0.0918367346938776	1.01226782847971	0.535862918189412	0.933364654934767
GO:0051879	Hsp90 protein binding	4/1691	42/18639	0.0952380952380952	1.04975922953451	0.536703728905966	0.933497511387727
GO:0005164	tumor necrosis factor receptor binding	3/1691	31/18639	0.0967741935483871	1.06669083001087	0.542853019671892	0.936446807559722
GO:0005452	solute:inorganic anion antiporter activity	3/1691	31/18639	0.0967741935483871	1.06669083001087	0.542853019671892	0.936446807559722
GO:0008327	methyl-CpG binding	3/1691	31/18639	0.0967741935483871	1.06669083001087	0.542853019671892	0.936446807559722
GO:0016878	acid-thiol ligase activity	3/1691	31/18639	0.0967741935483871	1.06669083001087	0.542853019671892	0.936446807559722
GO:0140457	protein demethylase activity	3/1691	31/18639	0.0967741935483871	1.06669083001087	0.542853019671892	0.936446807559722
GO:0140597	protein carrier chaperone	17/1691	188/18639	0.0904255319148936	0.996712885488884	0.543001097258217	0.936446807559722
GO:0160215	deacylase activity	6/1691	65/18639	0.0923076923076923	1.01745894554883	0.544883465792775	0.938367717535936
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	5/1691	54/18639	0.0925925925925926	1.02059925093633	0.549525536647734	0.944417885650533
GO:0016004	phospholipase activator activity	2/1691	20/18639	0.1	1.10224719101124	0.553037500606168	0.944417885650533
GO:0031418	L-ascorbic acid binding	2/1691	20/18639	0.1	1.10224719101124	0.553037500606168	0.944417885650533
GO:0043024	ribosomal small subunit binding	2/1691	20/18639	0.1	1.10224719101124	0.553037500606168	0.944417885650533
GO:0061608	nuclear import signal receptor activity	2/1691	20/18639	0.1	1.10224719101124	0.553037500606168	0.944417885650533
GO:0140939	histone H4 methyltransferase activity	2/1691	20/18639	0.1	1.10224719101124	0.553037500606168	0.944417885650533
GO:0003724	RNA helicase activity	7/1691	77/18639	0.0909090909090909	1.00204290091931	0.555489762908036	0.946452460391602
GO:0005245	voltage-gated calcium channel activity	4/1691	43/18639	0.0930232558139535	1.0253462241965	0.555779208927746	0.946452460391602
GO:0008235	metalloexopeptidase activity	6/1691	66/18639	0.0909090909090909	1.00204290091931	0.560223367249029	0.947131133747727
GO:0003727	single-stranded RNA binding	8/1691	89/18639	0.0898876404494382	0.990783991920212	0.564829934496818	0.947131133747727
GO:0042910	xenobiotic transmembrane transporter activity	3/1691	32/18639	0.09375	1.03335674157303	0.564891339847219	0.947131133747727
GO:0047498	calcium-dependent phospholipase A2 activity	3/1691	32/18639	0.09375	1.03335674157303	0.564891339847219	0.947131133747727
GO:0008374	O-acyltransferase activity	5/1691	55/18639	0.0909090909090909	1.00204290091931	0.56627774487111	0.947131133747727
GO:0043014	alpha-tubulin binding	4/1691	44/18639	0.0909090909090909	1.00204290091931	0.57442506494866	0.947131133747727
GO:0042054	histone methyltransferase activity	6/1691	67/18639	0.0895522388059701	0.98708703672648	0.575314881974135	0.947131133747727
GO:0010314	phosphatidylinositol-5-phosphate binding	2/1691	21/18639	0.0952380952380952	1.04975922953451	0.580073819099691	0.947131133747727
GO:0015125	bile acid transmembrane transporter activity	2/1691	21/18639	0.0952380952380952	1.04975922953451	0.580073819099691	0.947131133747727
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/1691	21/18639	0.0952380952380952	1.04975922953451	0.580073819099691	0.947131133747727
GO:0051428	peptide hormone receptor binding	2/1691	21/18639	0.0952380952380952	1.04975922953451	0.580073819099691	0.947131133747727
GO:0072542	protein phosphatase activator activity	2/1691	21/18639	0.0952380952380952	1.04975922953451	0.580073819099691	0.947131133747727
GO:0016741	transferase activity, transferring one-carbon groups	19/1691	215/18639	0.0883720930232558	0.974078912986674	0.583026757179893	0.947131133747727
GO:0008186	ATP-dependent activity, acting on RNA	7/1691	79/18639	0.0886075949367089	0.976674726212488	0.583353761001359	0.947131133747727
GO:0008168	methyltransferase activity	18/1691	204/18639	0.0882352941176471	0.972571050892267	0.585388652661737	0.947131133747727
GO:0019956	chemokine binding	3/1691	33/18639	0.0909090909090909	1.00204290091931	0.586266311362391	0.947131133747727
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	8/1691	91/18639	0.0879120879120879	0.969008519570317	0.590656125816233	0.947131133747727
GO:0004715	non-membrane spanning protein tyrosine kinase activity	4/1691	45/18639	0.0888888888888889	0.979775280898876	0.592619861449779	0.947131133747727
GO:0098960	postsynaptic neurotransmitter receptor activity	6/1691	69/18639	0.0869565217391304	0.95847581827064	0.604697383649419	0.947131133747727
GO:0004407	histone deacetylase activity	2/1691	22/18639	0.0909090909090909	1.00204290091931	0.605886620021685	0.947131133747727
GO:0008970	phospholipase A1 activity	2/1691	22/18639	0.0909090909090909	1.00204290091931	0.605886620021685	0.947131133747727
GO:0033558	protein lysine deacetylase activity	2/1691	22/18639	0.0909090909090909	1.00204290091931	0.605886620021685	0.947131133747727
GO:0050321	tau-protein kinase activity	2/1691	22/18639	0.0909090909090909	1.00204290091931	0.605886620021685	0.947131133747727
GO:0015035	protein-disulfide reductase activity	3/1691	34/18639	0.0882352941176471	0.972571050892267	0.606955992365554	0.947131133747727
GO:0016831	carboxy-lyase activity	3/1691	34/18639	0.0882352941176471	0.972571050892267	0.606955992365554	0.947131133747727
GO:0019825	oxygen binding	3/1691	34/18639	0.0882352941176471	0.972571050892267	0.606955992365554	0.947131133747727
GO:0052866	phosphatidylinositol phosphate phosphatase activity	3/1691	34/18639	0.0882352941176471	0.972571050892267	0.606955992365554	0.947131133747727
GO:0019842	vitamin binding	13/1691	150/18639	0.0866666666666667	0.955280898876405	0.610648168196674	0.947131133747727
GO:0004382	GDP phosphatase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0005528	FK506 binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0008190	eukaryotic initiation factor 4E binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0008239	dipeptidyl-peptidase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0008401	retinoic acid 4-hydroxylase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0015279	store-operated calcium channel activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0015643	toxic substance binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0016783	sulfurtransferase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0016868	intramolecular phosphotransferase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0019531	oxalate transmembrane transporter activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0031419	cobalamin binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0031434	mitogen-activated protein kinase kinase binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0031996	thioesterase binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0032356	oxidized DNA binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0032395	MHC class II receptor activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0035374	chondroitin sulfate binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0043422	protein kinase B binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0047429	nucleoside triphosphate diphosphatase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0051378	serotonin binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0051864	histone H3K36 demethylase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0070097	delta-catenin binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0071723	lipopeptide binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0099122	RNA polymerase II C-terminal domain binding	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0140999	histone H3K4 trimethyltransferase activity	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/1691	10/18639	0.1	1.10224719101124	0.61376305232275	0.947131133747727
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	5/1691	58/18639	0.0862068965517241	0.950213095699341	0.614520537280008	0.947131133747727
GO:0140767	enzyme-substrate adaptor activity	12/1691	139/18639	0.0863309352517986	0.951580308786679	0.615104914046558	0.947131133747727
GO:0051213	dioxygenase activity	8/1691	93/18639	0.0860215053763441	0.948169626676332	0.615715525349365	0.947131133747727
GO:0000510	H3-H4 histone complex chaperone activity	13/1691	151/18639	0.0860927152317881	0.948954535307687	0.620389183956491	0.947131133747727
GO:0140584	chromatin extrusion motor activity	13/1691	151/18639	0.0860927152317881	0.948954535307687	0.620389183956491	0.947131133747727
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	13/1691	151/18639	0.0860927152317881	0.948954535307687	0.620389183956491	0.947131133747727
GO:0140849	ATP-dependent H2AZ histone chaperone activity	13/1691	151/18639	0.0860927152317881	0.948954535307687	0.620389183956491	0.947131133747727
GO:0140566	histone reader activity	3/1691	35/18639	0.0857142857142857	0.944783306581059	0.6269443176478	0.947131133747727
GO:0099095	ligand-gated monoatomic anion channel activity	4/1691	47/18639	0.0851063829787234	0.938082715754243	0.627587484476848	0.947131133747727
GO:0140938	histone H3 methyltransferase activity	4/1691	47/18639	0.0851063829787234	0.938082715754243	0.627587484476848	0.947131133747727
GO:0015616	DNA translocase activity	13/1691	152/18639	0.0855263157894737	0.942711413364873	0.630010714746558	0.947131133747727
GO:0000295	adenine nucleotide transmembrane transporter activity	2/1691	23/18639	0.0869565217391304	0.95847581827064	0.63047525782115	0.947131133747727
GO:0016917	GABA receptor activity	2/1691	23/18639	0.0869565217391304	0.95847581827064	0.63047525782115	0.947131133747727
GO:0140713	histone chaperone activity	14/1691	164/18639	0.0853658536585366	0.940942724033982	0.634655439411387	0.947131133747727
GO:0008234	cysteine-type peptidase activity	16/1691	187/18639	0.0855614973262032	0.943099200865229	0.634889210132434	0.947131133747727
GO:0005254	chloride channel activity	7/1691	83/18639	0.0843373493975904	0.929606064708271	0.636352008086253	0.947131133747727
GO:0061775	cohesin loader activity	13/1691	153/18639	0.0849673202614379	0.93654990085922	0.639508780290545	0.947131133747727
GO:0008276	protein methyltransferase activity	8/1691	95/18639	0.0842105263157895	0.928208160851567	0.639943455013787	0.947131133747727
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	11/1691	130/18639	0.0846153846153846	0.93267070008643	0.640815810162667	0.947131133747727
GO:0038187	pattern recognition receptor activity	4/1691	48/18639	0.0833333333333333	0.918539325842697	0.644333796130916	0.947131133747727
GO:0140693	molecular condensate scaffold activity	4/1691	48/18639	0.0833333333333333	0.918539325842697	0.644333796130916	0.947131133747727
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	5/1691	60/18639	0.0833333333333333	0.918539325842697	0.644866763395096	0.947131133747727
GO:0016409	palmitoyltransferase activity	3/1691	36/18639	0.0833333333333333	0.918539325842697	0.646220536946691	0.947131133747727
GO:0045505	dynein intermediate chain binding	3/1691	36/18639	0.0833333333333333	0.918539325842697	0.646220536946691	0.947131133747727
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/1691	36/18639	0.0833333333333333	0.918539325842697	0.646220536946691	0.947131133747727
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/1691	36/18639	0.0833333333333333	0.918539325842697	0.646220536946691	0.947131133747727
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/1691	36/18639	0.0833333333333333	0.918539325842697	0.646220536946691	0.947131133747727
GO:0001851	complement component C3b binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0008172	S-methyltransferase activity	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0008199	ferric iron binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0008526	phosphatidylinositol transfer activity	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0016594	glycine binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0031731	CCR6 chemokine receptor binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0032794	GTPase activating protein binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0034056	estrogen response element binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0034511	U3 snoRNA binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0042608	T cell receptor binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0043522	leucine zipper domain binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0048407	platelet-derived growth factor binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0070990	snRNP binding	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0140537	transcription regulator activator activity	1/1691	11/18639	0.0909090909090909	1.00204290091931	0.648822726944159	0.947131133747727
GO:0005262	calcium channel activity	11/1691	131/18639	0.083969465648855	0.925551076421649	0.650938268930974	0.947131133747727
GO:0001091	RNA polymerase II general transcription initiation factor binding	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0015149	hexose transmembrane transporter activity	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0015295	solute:proton symporter activity	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0055056	D-glucose transmembrane transporter activity	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0070840	dynein complex binding	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0140033	acetylation-dependent protein binding	2/1691	24/18639	0.0833333333333333	0.918539325842697	0.653849269074239	0.947131133747727
GO:0004843	cysteine-type deubiquitinase activity	9/1691	108/18639	0.0833333333333333	0.918539325842697	0.654687772134681	0.947131133747727
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	5/1691	61/18639	0.0819672131147541	0.90348130410757	0.659464203305054	0.947131133747727
GO:0043539	protein serine/threonine kinase activator activity	6/1691	73/18639	0.0821917808219178	0.905956595351701	0.659950718248327	0.947131133747727
GO:0000030	mannosyltransferase activity	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0003707	nuclear steroid receptor activity	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0008139	nuclear localization sequence binding	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0015645	fatty acid ligase activity	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0015662	P-type ion transporter activity	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0019707	protein-cysteine S-acyltransferase activity	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0042974	nuclear retinoic acid receptor binding	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0047617	fatty acyl-CoA hydrolase activity	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0120515	fatty acid-CoA ligase activity	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:0140358	P-type transmembrane transporter activity	2/1691	25/18639	0.08	0.881797752808989	0.676026532261419	0.947131133747727
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	10/1691	122/18639	0.0819672131147541	0.90348130410757	0.678190218103708	0.947131133747727
GO:0003995	acyl-CoA dehydrogenase activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0004000	adenosine deaminase activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0004300	enoyl-CoA hydratase activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0005095	GTPase inhibitor activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0005247	voltage-gated chloride channel activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0005527	macrolide binding	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0008504	monoamine transmembrane transporter activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0015132	prostaglandin transmembrane transporter activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0015166	polyol transmembrane transporter activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0015368	calcium:monoatomic cation antiporter activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0016208	AMP binding	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0016273	arginine N-methyltransferase activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0016274	protein-arginine N-methyltransferase activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0017166	vinculin binding	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0031543	peptidyl-proline dioxygenase activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0042301	phosphate ion binding	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0045295	gamma-catenin binding	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0070679	inositol 1,4,5 trisphosphate binding	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0097371	MDM2/MDM4 family protein binding	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/1691	12/18639	0.0833333333333333	0.918539325842697	0.680701660202556	0.947131133747727
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	15/1691	181/18639	0.0828729281767956	0.913464522937488	0.681794470757156	0.947131133747727
GO:0005501	retinoid binding	3/1691	38/18639	0.0789473684210526	0.870195150798344	0.682617033331695	0.947131133747727
GO:0019840	isoprenoid binding	3/1691	38/18639	0.0789473684210526	0.870195150798344	0.682617033331695	0.947131133747727
GO:0003743	translation initiation factor activity	4/1691	51/18639	0.0784313725490196	0.864507600793126	0.691523033008873	0.948062770125905
GO:0016597	amino acid binding	4/1691	51/18639	0.0784313725490196	0.864507600793126	0.691523033008873	0.948062770125905
GO:0030544	Hsp70 protein binding	4/1691	51/18639	0.0784313725490196	0.864507600793126	0.691523033008873	0.948062770125905
GO:0005216	monoatomic ion channel activity	38/1691	448/18639	0.0848214285714286	0.934941813804173	0.69413536239166	0.948062770125905
GO:0043130	ubiquitin binding	8/1691	100/18639	0.08	0.881797752808989	0.696555244893081	0.948062770125905
GO:0004197	cysteine-type endopeptidase activity	7/1691	88/18639	0.0795454545454545	0.876787538304392	0.696812683570284	0.948062770125905
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/1691	26/18639	0.0769230769230769	0.847882454624028	0.69703167732713	0.948062770125905
GO:0005112	Notch binding	2/1691	26/18639	0.0769230769230769	0.847882454624028	0.69703167732713	0.948062770125905
GO:0015145	monosaccharide transmembrane transporter activity	2/1691	26/18639	0.0769230769230769	0.847882454624028	0.69703167732713	0.948062770125905
GO:0015216	purine nucleotide transmembrane transporter activity	2/1691	26/18639	0.0769230769230769	0.847882454624028	0.69703167732713	0.948062770125905
GO:0016289	acyl-CoA hydrolase activity	2/1691	26/18639	0.0769230769230769	0.847882454624028	0.69703167732713	0.948062770125905
GO:0019865	immunoglobulin binding	2/1691	26/18639	0.0769230769230769	0.847882454624028	0.69703167732713	0.948062770125905
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/1691	39/18639	0.0769230769230769	0.847882454624028	0.699737684401626	0.948062770125905
GO:0005085	guanyl-nucleotide exchange factor activity	19/1691	230/18639	0.0826086956521739	0.910552027357108	0.700072236293026	0.948062770125905
GO:0046982	protein heterodimerization activity	31/1691	369/18639	0.0840108401084011	0.926007125239792	0.701204346176117	0.948062770125905
GO:0003689	DNA clamp loader activity	13/1691	160/18639	0.08125	0.895575842696629	0.702258833720045	0.948062770125905
GO:0015079	potassium ion transmembrane transporter activity	13/1691	160/18639	0.08125	0.895575842696629	0.702258833720045	0.948062770125905
GO:0008509	monoatomic anion transmembrane transporter activity	12/1691	149/18639	0.0805369127516778	0.887715858532539	0.709333998543661	0.948062770125905
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0008035	high-density lipoprotein particle binding	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0008253	5'-nucleotidase activity	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0019104	DNA N-glycosylase activity	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0019855	calcium channel inhibitor activity	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0030955	potassium ion binding	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0031432	titin binding	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0035325	Toll-like receptor binding	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0035673	oligopeptide transmembrane transporter activity	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0046975	histone H3K36 methyltransferase activity	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0051011	microtubule minus-end binding	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0070700	BMP receptor binding	1/1691	13/18639	0.0769230769230769	0.847882454624028	0.709688265270333	0.948062770125905
GO:0016887	ATP hydrolysis activity	35/1691	417/18639	0.0839328537170264	0.925147522431493	0.712005529515148	0.950118854139886
GO:0032451	demethylase activity	3/1691	40/18639	0.075	0.826685393258427	0.716146044740034	0.952479267548017
GO:0071855	neuropeptide receptor binding	3/1691	40/18639	0.075	0.826685393258427	0.716146044740034	0.952479267548017
GO:0008395	steroid hydroxylase activity	2/1691	27/18639	0.0740740740740741	0.816479400749064	0.716894714886673	0.952479267548017
GO:0035255	ionotropic glutamate receptor binding	2/1691	27/18639	0.0740740740740741	0.816479400749064	0.716894714886673	0.952479267548017
GO:0003713	transcription coactivator activity	21/1691	256/18639	0.08203125	0.904187148876405	0.718390739966962	0.953429449456153
GO:0051018	protein kinase A binding	4/1691	53/18639	0.0754716981132075	0.83188467246131	0.720407328691164	0.955067696343009
GO:0101005	deubiquitinase activity	9/1691	115/18639	0.0782608695652174	0.862628236443576	0.726461311168629	0.957093420950224
GO:0008227	G protein-coupled amine receptor activity	3/1691	41/18639	0.0731707317073171	0.80652233488627	0.731850442072252	0.957093420950224
GO:0016877	ligase activity, forming carbon-sulfur bonds	3/1691	41/18639	0.0731707317073171	0.80652233488627	0.731850442072252	0.957093420950224
GO:0005242	inward rectifier potassium channel activity	2/1691	28/18639	0.0714285714285714	0.787319422150883	0.735649858352312	0.957093420950224
GO:0051119	sugar transmembrane transporter activity	2/1691	28/18639	0.0714285714285714	0.787319422150883	0.735649858352312	0.957093420950224
GO:0051959	dynein light intermediate chain binding	2/1691	28/18639	0.0714285714285714	0.787319422150883	0.735649858352312	0.957093420950224
GO:0005347	ATP transmembrane transporter activity	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0015386	potassium:proton antiporter activity	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0016530	metallochaperone activity	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0019992	diacylglycerol binding	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0030983	mismatched DNA binding	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0032454	histone H3K9 demethylase activity	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0043176	amine binding	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0098599	palmitoyl hydrolase activity	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:1990825	sequence-specific mRNA binding	1/1691	14/18639	0.0714285714285714	0.787319422150883	0.736044817585799	0.957093420950224
GO:0052689	carboxylic ester hydrolase activity	7/1691	92/18639	0.0760869565217391	0.83866634098681	0.740180584537106	0.960633533200409
GO:0022836	gated channel activity	26/1691	318/18639	0.0817610062893082	0.901208395166419	0.740502836488053	0.960633533200409
GO:0016859	cis-trans isomerase activity	3/1691	42/18639	0.0714285714285714	0.787319422150883	0.746861727700427	0.960633533200409
GO:0048487	beta-tubulin binding	3/1691	42/18639	0.0714285714285714	0.787319422150883	0.746861727700427	0.960633533200409
GO:0140104	molecular carrier activity	20/1691	249/18639	0.0803212851405622	0.885339109245973	0.748771028696496	0.960633533200409
GO:0005506	iron ion binding	12/1691	154/18639	0.0779220779220779	0.85889391507369	0.750610462548109	0.960633533200409
GO:0016417	S-acyltransferase activity	2/1691	29/18639	0.0689655172413793	0.760170476559473	0.753334515288204	0.960633533200409
GO:0004497	monooxygenase activity	8/1691	106/18639	0.0754716981132075	0.83188467246131	0.756506715298705	0.960633533200409
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0008020	G protein-coupled photoreceptor activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0008252	nucleotidase activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0015116	sulfate transmembrane transporter activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0015250	water channel activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0015929	hexosaminidase activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0016846	carbon-sulfur lyase activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0017081	chloride channel regulator activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0030553	cGMP binding	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0031005	filamin binding	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0031386	protein tag activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0042809	nuclear vitamin D receptor binding	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0047372	monoacylglycerol lipase activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0050780	dopamine receptor binding	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0061578	K63-linked deubiquitinase activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0140161	monocarboxylate:sodium symporter activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0141047	molecular tag activity	1/1691	15/18639	0.0666666666666667	0.734831460674157	0.760009822335459	0.960633533200409
GO:0016279	protein-lysine N-methyltransferase activity	5/1691	69/18639	0.072463768115942	0.798729848558867	0.761835753337662	0.961945661660067
GO:0016853	isomerase activity	14/1691	180/18639	0.0777777777777778	0.857303370786517	0.76486439187786	0.964772130664119
GO:0048019	receptor antagonist activity	2/1691	30/18639	0.0666666666666667	0.734831460674157	0.769988427010693	0.968234674953714
GO:0051721	protein phosphatase 2A binding	2/1691	30/18639	0.0666666666666667	0.734831460674157	0.769988427010693	0.968234674953714
GO:0070566	adenylyltransferase activity	2/1691	30/18639	0.0666666666666667	0.734831460674157	0.769988427010693	0.968234674953714
GO:0032182	ubiquitin-like protein binding	9/1691	120/18639	0.075	0.826685393258427	0.771212447175825	0.96877612963136
GO:0016278	lysine N-methyltransferase activity	5/1691	70/18639	0.0714285714285714	0.787319422150883	0.772825870705693	0.969805126548459
GO:0019205	nucleobase-containing compound kinase activity	3/1691	44/18639	0.0681818181818182	0.751532175689479	0.774858856973724	0.971357971627225
GO:0015108	chloride transmembrane transporter activity	9/1691	121/18639	0.0743801652892562	0.819853282570341	0.779500776751658	0.971965813211097
GO:0003688	DNA replication origin binding	1/1691	16/18639	0.0625	0.688904494382023	0.781800167612023	0.971965813211097
GO:0015378	sodium:chloride symporter activity	1/1691	16/18639	0.0625	0.688904494382023	0.781800167612023	0.971965813211097
GO:0015562	efflux transmembrane transporter activity	1/1691	16/18639	0.0625	0.688904494382023	0.781800167612023	0.971965813211097
GO:0017070	U6 snRNA binding	1/1691	16/18639	0.0625	0.688904494382023	0.781800167612023	0.971965813211097
GO:0019841	retinol binding	1/1691	16/18639	0.0625	0.688904494382023	0.781800167612023	0.971965813211097
GO:0022858	alanine transmembrane transporter activity	1/1691	16/18639	0.0625	0.688904494382023	0.781800167612023	0.971965813211097
GO:0043023	ribosomal large subunit binding	1/1691	16/18639	0.0625	0.688904494382023	0.781800167612023	0.971965813211097
GO:0005184	neuropeptide hormone activity	2/1691	31/18639	0.0645161290322581	0.711127220007249	0.785652937861645	0.971965813211097
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/1691	31/18639	0.0645161290322581	0.711127220007249	0.785652937861645	0.971965813211097
GO:0046915	transition metal ion transmembrane transporter activity	3/1691	45/18639	0.0666666666666667	0.734831460674157	0.787875928082577	0.971965813211097
GO:0070063	RNA polymerase binding	4/1691	59/18639	0.0677966101694915	0.747286231194058	0.794911485988232	0.971965813211097
GO:0005261	monoatomic cation channel activity	27/1691	341/18639	0.0791788856304985	0.872747042736169	0.798809872698314	0.971965813211097
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/1691	46/18639	0.0652173913043478	0.71885686370298	0.800261765458828	0.971965813211097
GO:0015106	bicarbonate transmembrane transporter activity	2/1691	32/18639	0.0625	0.688904494382023	0.800370377729274	0.971965813211097
GO:0022884	macromolecule transmembrane transporter activity	2/1691	32/18639	0.0625	0.688904494382023	0.800370377729274	0.971965813211097
GO:0140142	nucleocytoplasmic carrier activity	2/1691	32/18639	0.0625	0.688904494382023	0.800370377729274	0.971965813211097
GO:0160041	neuropeptide activity	2/1691	32/18639	0.0625	0.688904494382023	0.800370377729274	0.971965813211097
GO:0004549	tRNA-specific ribonuclease activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0004550	nucleoside diphosphate kinase activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0004659	prenyltransferase activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0005092	GDP-dissociation inhibitor activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0008429	phosphatidylethanolamine binding	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0008569	minus-end-directed microtubule motor activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0009881	photoreceptor activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0016018	cyclosporin A binding	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0016805	dipeptidase activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0017110	nucleoside diphosphate phosphatase activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0030548	acetylcholine receptor regulator activity	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0032183	SUMO binding	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0070402	NADPH binding	1/1691	17/18639	0.0588235294117647	0.648380700594845	0.801613082640111	0.971965813211097
GO:0046873	metal ion transmembrane transporter activity	36/1691	450/18639	0.08	0.881797752808989	0.810698954944094	0.974970136941763
GO:0061733	protein-lysine-acetyltransferase activity	3/1691	47/18639	0.0638297872340425	0.703562036815683	0.812035011889417	0.974970136941763
GO:0061749	forked DNA-dependent helicase activity	3/1691	47/18639	0.0638297872340425	0.703562036815683	0.812035011889417	0.974970136941763
GO:1990518	single-stranded 3'-5' DNA helicase activity	3/1691	47/18639	0.0638297872340425	0.703562036815683	0.812035011889417	0.974970136941763
GO:0003684	damaged DNA binding	5/1691	74/18639	0.0675675675675676	0.744761615548132	0.812919343209883	0.974970136941763
GO:0000900	mRNA regulatory element binding translation repressor activity	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0005372	water transmembrane transporter activity	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0015172	acidic amino acid transmembrane transporter activity	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0015280	ligand-gated sodium channel activity	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0015373	monoatomic anion:sodium symporter activity	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0016854	racemase and epimerase activity	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0050811	GABA receptor binding	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0099602	neurotransmitter receptor regulator activity	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:1990381	ubiquitin-specific protease binding	1/1691	18/18639	0.0555555555555556	0.612359550561798	0.819627918707964	0.974970136941763
GO:0009378	four-way junction helicase activity	3/1691	48/18639	0.0625	0.688904494382023	0.823215092939984	0.974970136941763
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	3/1691	48/18639	0.0625	0.688904494382023	0.823215092939984	0.974970136941763
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/1691	48/18639	0.0625	0.688904494382023	0.823215092939984	0.974970136941763
GO:0032266	phosphatidylinositol-3-phosphate binding	3/1691	48/18639	0.0625	0.688904494382023	0.823215092939984	0.974970136941763
GO:0036121	double-stranded DNA helicase activity	3/1691	48/18639	0.0625	0.688904494382023	0.823215092939984	0.974970136941763
GO:0043138	3'-5' DNA helicase activity	3/1691	48/18639	0.0625	0.688904494382023	0.823215092939984	0.974970136941763
GO:0019783	ubiquitin-like protein peptidase activity	9/1691	127/18639	0.0708661417322835	0.781120056622136	0.824676594804271	0.974970136941763
GO:0015291	secondary active transmembrane transporter activity	22/1691	287/18639	0.0766550522648084	0.844928160357045	0.82572660811456	0.974970136941763
GO:0015103	inorganic anion transmembrane transporter activity	12/1691	165/18639	0.0727272727272727	0.801634320735444	0.826902169263824	0.974970136941763
GO:0015020	glucuronosyltransferase activity	2/1691	34/18639	0.0588235294117647	0.648380700594845	0.827135265234816	0.974970136941763
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/1691	34/18639	0.0588235294117647	0.648380700594845	0.827135265234816	0.974970136941763
GO:0051427	hormone receptor binding	2/1691	34/18639	0.0588235294117647	0.648380700594845	0.827135265234816	0.974970136941763
GO:0001653	peptide receptor activity	9/1691	128/18639	0.0703125	0.775017556179775	0.831464472042888	0.974970136941763
GO:0015399	primary active transmembrane transporter activity	12/1691	166/18639	0.072289156626506	0.796805198321375	0.832862842905603	0.974970136941763
GO:1901682	sulfur compound transmembrane transporter activity	4/1691	63/18639	0.0634920634920635	0.69983948635634	0.835065137046787	0.974970136941763
GO:0008301	DNA binding, bending	1/1691	19/18639	0.0526315789473684	0.580130100532229	0.836007768848388	0.974970136941763
GO:0008574	plus-end-directed microtubule motor activity	1/1691	19/18639	0.0526315789473684	0.580130100532229	0.836007768848388	0.974970136941763
GO:0022821	solute:potassium antiporter activity	1/1691	19/18639	0.0526315789473684	0.580130100532229	0.836007768848388	0.974970136941763
GO:0034987	immunoglobulin receptor binding	1/1691	19/18639	0.0526315789473684	0.580130100532229	0.836007768848388	0.974970136941763
GO:0042834	peptidoglycan binding	1/1691	19/18639	0.0526315789473684	0.580130100532229	0.836007768848388	0.974970136941763
GO:0046624	sphingolipid transporter activity	1/1691	19/18639	0.0526315789473684	0.580130100532229	0.836007768848388	0.974970136941763
GO:0097001	ceramide binding	1/1691	19/18639	0.0526315789473684	0.580130100532229	0.836007768848388	0.974970136941763
GO:1990380	K48-linked deubiquitinase activity	1/1691	19/18639	0.0526315789473684	0.580130100532229	0.836007768848388	0.974970136941763
GO:0009055	electron transfer activity	8/1691	116/18639	0.0689655172413793	0.760170476559473	0.836791067228193	0.974970136941763
GO:0000175	3'-5'-RNA exonuclease activity	2/1691	35/18639	0.0571428571428571	0.629855537720706	0.83926804993706	0.974970136941763
GO:0005343	organic acid:sodium symporter activity	2/1691	35/18639	0.0571428571428571	0.629855537720706	0.83926804993706	0.974970136941763
GO:0043015	gamma-tubulin binding	2/1691	35/18639	0.0571428571428571	0.629855537720706	0.83926804993706	0.974970136941763
GO:0061631	ubiquitin conjugating enzyme activity	2/1691	35/18639	0.0571428571428571	0.629855537720706	0.83926804993706	0.974970136941763
GO:0000993	RNA polymerase II complex binding	2/1691	36/18639	0.0555555555555556	0.612359550561798	0.850623785995317	0.974970136941763
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/1691	36/18639	0.0555555555555556	0.612359550561798	0.850623785995317	0.974970136941763
GO:0005484	SNAP receptor activity	2/1691	36/18639	0.0555555555555556	0.612359550561798	0.850623785995317	0.974970136941763
GO:0000339	RNA cap binding	1/1691	20/18639	0.05	0.551123595505618	0.850900940861137	0.974970136941763
GO:0001614	purinergic nucleotide receptor activity	1/1691	20/18639	0.05	0.551123595505618	0.850900940861137	0.974970136941763
GO:0001972	retinoic acid binding	1/1691	20/18639	0.05	0.551123595505618	0.850900940861137	0.974970136941763
GO:0016408	C-acyltransferase activity	1/1691	20/18639	0.05	0.551123595505618	0.850900940861137	0.974970136941763
GO:0016502	nucleotide receptor activity	1/1691	20/18639	0.05	0.551123595505618	0.850900940861137	0.974970136941763
GO:0005179	hormone activity	9/1691	132/18639	0.0681818181818182	0.751532175689479	0.856591904940881	0.974970136941763
GO:0000149	SNARE binding	7/1691	106/18639	0.0660377358490566	0.727899088403646	0.856911612136646	0.974970136941763
GO:0022829	wide pore channel activity	2/1691	37/18639	0.0540540540540541	0.595809292438506	0.86124350648405	0.974970136941763
GO:0035613	RNA stem-loop binding	1/1691	21/18639	0.0476190476190476	0.524879614767255	0.864442296949209	0.974970136941763
GO:0051010	microtubule plus-end binding	1/1691	21/18639	0.0476190476190476	0.524879614767255	0.864442296949209	0.974970136941763
GO:0061891	calcium ion sensor activity	1/1691	21/18639	0.0476190476190476	0.524879614767255	0.864442296949209	0.974970136941763
GO:0070182	DNA polymerase binding	1/1691	21/18639	0.0476190476190476	0.524879614767255	0.864442296949209	0.974970136941763
GO:1904047	S-adenosyl-L-methionine binding	1/1691	21/18639	0.0476190476190476	0.524879614767255	0.864442296949209	0.974970136941763
GO:0016410	N-acyltransferase activity	6/1691	94/18639	0.0638297872340425	0.703562036815683	0.865401881522233	0.974970136941763
GO:0008094	ATP-dependent activity, acting on DNA	15/1691	210/18639	0.0714285714285714	0.787319422150883	0.866322846181848	0.974970136941763
GO:0003697	single-stranded DNA binding	8/1691	121/18639	0.0661157024793388	0.728758473395858	0.868283556792485	0.974970136941763
GO:0008173	RNA methyltransferase activity	4/1691	67/18639	0.0597014925373134	0.65805802448432	0.868425120883264	0.974970136941763
GO:0004864	protein phosphatase inhibitor activity	3/1691	53/18639	0.0566037735849057	0.623913504345983	0.870929081625722	0.974970136941763
GO:0034212	protein N-acetyltransferase activity	3/1691	53/18639	0.0566037735849057	0.623913504345983	0.870929081625722	0.974970136941763
GO:0140296	general transcription initiation factor binding	3/1691	53/18639	0.0566037735849057	0.623913504345983	0.870929081625722	0.974970136941763
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/1691	38/18639	0.0526315789473684	0.580130100532229	0.871167199436959	0.974970136941763
GO:0042162	telomeric DNA binding	2/1691	38/18639	0.0526315789473684	0.580130100532229	0.871167199436959	0.974970136941763
GO:0042887	amide transmembrane transporter activity	2/1691	38/18639	0.0526315789473684	0.580130100532229	0.871167199436959	0.974970136941763
GO:0008528	G protein-coupled peptide receptor activity	8/1691	122/18639	0.0655737704918033	0.722785043286056	0.87394768293239	0.974970136941763
GO:0015377	chloride:monoatomic cation symporter activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0016881	acid-amino acid ligase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0032931	histone H3K56 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0033038	bitter taste receptor activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0033691	sialic acid binding	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0043992	histone H3K9 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0043993	histone H3K18 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0043994	histone H3K23 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0043999	histone H2AK5 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0044012	histone H2AK9 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0044014	histone H2BK5 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0044015	histone H2BK12 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0044016	histone H3K4 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0044017	histone H3K27 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0044018	histone H3K36 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0046972	histone H4K16 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0070034	telomerase RNA binding	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0140035	ubiquitin-like protein reader activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0140784	metal ion sensor activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0140908	histone H3K122 acetyltransferase activity	1/1691	22/18639	0.0454545454545455	0.501021450459653	0.876754472040996	0.974970136941763
GO:0017069	snRNA binding	3/1691	54/18639	0.0555555555555556	0.612359550561798	0.878979152776963	0.976554636524724
GO:0000217	DNA secondary structure binding	2/1691	39/18639	0.0512820512820513	0.565254969749352	0.880433659709139	0.977281362277144
GO:0003887	DNA-directed DNA polymerase activity	1/1691	23/18639	0.0434782608695652	0.47923790913532	0.887948981778261	0.979390882340792
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/1691	23/18639	0.0434782608695652	0.47923790913532	0.887948981778261	0.979390882340792
GO:0005283	amino acid:sodium symporter activity	1/1691	23/18639	0.0434782608695652	0.47923790913532	0.887948981778261	0.979390882340792
GO:0044013	histone H2B acetyltransferase activity	1/1691	23/18639	0.0434782608695652	0.47923790913532	0.887948981778261	0.979390882340792
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/1691	23/18639	0.0434782608695652	0.47923790913532	0.887948981778261	0.979390882340792
GO:0070577	lysine-acetylated histone binding	1/1691	23/18639	0.0434782608695652	0.47923790913532	0.887948981778261	0.979390882340792
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/1691	23/18639	0.0434782608695652	0.47923790913532	0.887948981778261	0.979390882340792
GO:0004532	RNA exonuclease activity	2/1691	40/18639	0.05	0.551123595505618	0.889080376286461	0.979753735961885
GO:0061630	ubiquitin protein ligase activity	26/1691	353/18639	0.0736543909348442	0.811853455135754	0.891633642307836	0.979994055425672
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	16/1691	229/18639	0.0698689956331878	0.770129041754575	0.892561565655803	0.979994055425672
GO:0046906	tetrapyrrole binding	10/1691	152/18639	0.0657894736842105	0.725162625665287	0.89260620521861	0.979994055425672
GO:0019212	phosphatase inhibitor activity	3/1691	56/18639	0.0535714285714286	0.590489566613162	0.893750383418722	0.979994055425672
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/1691	41/18639	0.0487804878048781	0.537681556590847	0.897143449835907	0.979994055425672
GO:0008137	NADH dehydrogenase (ubiquinone) activity	2/1691	41/18639	0.0487804878048781	0.537681556590847	0.897143449835907	0.979994055425672
GO:0042169	SH2 domain binding	2/1691	41/18639	0.0487804878048781	0.537681556590847	0.897143449835907	0.979994055425672
GO:0061650	ubiquitin-like protein conjugating enzyme activity	2/1691	41/18639	0.0487804878048781	0.537681556590847	0.897143449835907	0.979994055425672
GO:0005315	phosphate transmembrane transporter activity	1/1691	24/18639	0.0416666666666667	0.459269662921348	0.898127230156697	0.979994055425672
GO:0019957	C-C chemokine binding	1/1691	24/18639	0.0416666666666667	0.459269662921348	0.898127230156697	0.979994055425672
GO:0043998	histone H2A acetyltransferase activity	1/1691	24/18639	0.0416666666666667	0.459269662921348	0.898127230156697	0.979994055425672
GO:0031492	nucleosomal DNA binding	2/1691	42/18639	0.0476190476190476	0.524879614767255	0.904657535942681	0.983720044443357
GO:0043175	RNA polymerase core enzyme binding	2/1691	42/18639	0.0476190476190476	0.524879614767255	0.904657535942681	0.983720044443357
GO:0004386	helicase activity	10/1691	155/18639	0.0645161290322581	0.711127220007249	0.905314030213128	0.983720044443357
GO:0020037	heme binding	9/1691	142/18639	0.0633802816901408	0.698607374584586	0.906429107681371	0.983720044443357
GO:0017116	single-stranded DNA helicase activity	3/1691	58/18639	0.0517241379310345	0.570127857419605	0.90688156172847	0.983720044443357
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/1691	25/18639	0.04	0.440898876404494	0.907381425902334	0.983720044443357
GO:0017056	structural constituent of nuclear pore	1/1691	25/18639	0.04	0.440898876404494	0.907381425902334	0.983720044443357
GO:0022804	active transmembrane transporter activity	34/1691	457/18639	0.074398249452954	0.820052614756718	0.908340159983072	0.983720044443357
GO:0016651	oxidoreductase activity, acting on NAD(P)H	5/1691	88/18639	0.0568181818181818	0.626276813074566	0.910555518689164	0.983720044443357
GO:0036002	pre-mRNA binding	3/1691	59/18639	0.0508474576271186	0.560464673395544	0.912879958643126	0.983720044443357
GO:0005227	calcium-activated cation channel activity	1/1691	26/18639	0.0384615384615385	0.423941227312014	0.915795415845342	0.983720044443357
GO:0008157	protein phosphatase 1 binding	1/1691	26/18639	0.0384615384615385	0.423941227312014	0.915795415845342	0.983720044443357
GO:0008198	ferrous iron binding	1/1691	26/18639	0.0384615384615385	0.423941227312014	0.915795415845342	0.983720044443357
GO:0034237	protein kinase A regulatory subunit binding	1/1691	26/18639	0.0384615384615385	0.423941227312014	0.915795415845342	0.983720044443357
GO:0097602	cullin family protein binding	1/1691	26/18639	0.0384615384615385	0.423941227312014	0.915795415845342	0.983720044443357
GO:0120014	phospholipid transfer activity	1/1691	26/18639	0.0384615384615385	0.423941227312014	0.915795415845342	0.983720044443357
GO:0003954	NADH dehydrogenase activity	2/1691	44/18639	0.0454545454545455	0.501021450459653	0.918169950679541	0.983720044443357
GO:0016790	thiolester hydrolase activity	2/1691	44/18639	0.0454545454545455	0.501021450459653	0.918169950679541	0.983720044443357
GO:0001098	basal transcription machinery binding	3/1691	60/18639	0.05	0.551123595505618	0.918524747720477	0.983720044443357
GO:0001099	basal RNA polymerase II transcription machinery binding	3/1691	60/18639	0.05	0.551123595505618	0.918524747720477	0.983720044443357
GO:0015078	proton transmembrane transporter activity	12/1691	185/18639	0.0648648648648649	0.714971150926207	0.91863867568302	0.983720044443357
GO:0022853	active monoatomic ion transmembrane transporter activity	7/1691	118/18639	0.0593220338983051	0.653875452294801	0.919266642678026	0.983720044443357
GO:0008320	protein transmembrane transporter activity	1/1691	27/18639	0.037037037037037	0.408239700374532	0.923445442805291	0.986014751551363
GO:0015252	proton channel activity	1/1691	27/18639	0.037037037037037	0.408239700374532	0.923445442805291	0.986014751551363
GO:0019905	syntaxin binding	3/1691	61/18639	0.0491803278688525	0.542088782464542	0.923833641093169	0.986014751551363
GO:0003823	antigen binding	11/1691	174/18639	0.0632183908045977	0.696822936846184	0.925784551442196	0.986084785594815
GO:0008527	taste receptor activity	1/1691	28/18639	0.0357142857142857	0.393659711075441	0.930400834822068	0.986084785594815
GO:0016866	intramolecular transferase activity	1/1691	28/18639	0.0357142857142857	0.393659711075441	0.930400834822068	0.986084785594815
GO:0019789	SUMO transferase activity	1/1691	28/18639	0.0357142857142857	0.393659711075441	0.930400834822068	0.986084785594815
GO:0036408	histone H3K14 acetyltransferase activity	1/1691	28/18639	0.0357142857142857	0.393659711075441	0.930400834822068	0.986084785594815
GO:0046966	nuclear thyroid hormone receptor binding	1/1691	28/18639	0.0357142857142857	0.393659711075441	0.930400834822068	0.986084785594815
GO:0051537	2 iron, 2 sulfur cluster binding	1/1691	28/18639	0.0357142857142857	0.393659711075441	0.930400834822068	0.986084785594815
GO:0015081	sodium ion transmembrane transporter activity	10/1691	164/18639	0.0609756097560976	0.672101945738559	0.936104114001209	0.986084785594815
GO:0003785	actin monomer binding	1/1691	29/18639	0.0344827586206897	0.380085238279737	0.936724631948277	0.986084785594815
GO:0004181	metallocarboxypeptidase activity	1/1691	29/18639	0.0344827586206897	0.380085238279737	0.936724631948277	0.986084785594815
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/1691	29/18639	0.0344827586206897	0.380085238279737	0.936724631948277	0.986084785594815
GO:0005416	amino acid:monoatomic cation symporter activity	1/1691	29/18639	0.0344827586206897	0.380085238279737	0.936724631948277	0.986084785594815
GO:0010484	histone H3 acetyltransferase activity	1/1691	29/18639	0.0344827586206897	0.380085238279737	0.936724631948277	0.986084785594815
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/1691	29/18639	0.0344827586206897	0.380085238279737	0.936724631948277	0.986084785594815
GO:0097472	cyclin-dependent protein kinase activity	1/1691	29/18639	0.0344827586206897	0.380085238279737	0.936724631948277	0.986084785594815
GO:0016755	aminoacyltransferase activity	36/1691	496/18639	0.0725806451612903	0.800018122508155	0.9375811862448	0.986084785594815
GO:0061659	ubiquitin-like protein ligase activity	26/1691	372/18639	0.0698924731182796	0.77038782167452	0.938157774210899	0.986084785594815
GO:0008188	neuropeptide receptor activity	2/1691	48/18639	0.0416666666666667	0.459269662921348	0.939966601163155	0.986084785594815
GO:0004842	ubiquitin-protein transferase activity	32/1691	449/18639	0.0712694877505568	0.785565926778609	0.941776904852762	0.986084785594815
GO:0022839	monoatomic ion-gated channel activity	1/1691	30/18639	0.0333333333333333	0.367415730337079	0.94247415625647	0.986084785594815
GO:0043995	histone H4K5 acetyltransferase activity	1/1691	30/18639	0.0333333333333333	0.367415730337079	0.94247415625647	0.986084785594815
GO:0043996	histone H4K8 acetyltransferase activity	1/1691	30/18639	0.0333333333333333	0.367415730337079	0.94247415625647	0.986084785594815
GO:0043997	histone H4K12 acetyltransferase activity	1/1691	30/18639	0.0333333333333333	0.367415730337079	0.94247415625647	0.986084785594815
GO:0003774	cytoskeletal motor activity	9/1691	153/18639	0.0588235294117647	0.648380700594845	0.943533116611257	0.986118263663234
GO:0042393	histone binding	16/1691	247/18639	0.0647773279352227	0.714006277578129	0.944121417053498	0.986118263663234
GO:0005048	signal sequence binding	2/1691	51/18639	0.0392156862745098	0.432253800396563	0.952564220056452	0.992300242901181
GO:0003777	microtubule motor activity	3/1691	68/18639	0.0441176470588235	0.486285525446134	0.95295520146101	0.992300242901181
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	3/1691	68/18639	0.0441176470588235	0.486285525446134	0.95295520146101	0.992300242901181
GO:0004527	exonuclease activity	4/1691	84/18639	0.0476190476190476	0.524879614767255	0.953290896742903	0.992300242901181
GO:0008080	N-acetyltransferase activity	3/1691	69/18639	0.0434782608695652	0.47923790913532	0.956143540887096	0.993386396683358
GO:0015276	ligand-gated monoatomic ion channel activity	11/1691	186/18639	0.0591397849462366	0.651866618339978	0.9562196564883	0.993386396683358
GO:0019239	deaminase activity	1/1691	33/18639	0.0303030303030303	0.334014300306435	0.956775104422301	0.993386396683358
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/1691	53/18639	0.0377358490566038	0.415942336230655	0.959513227520898	0.994927121755357
GO:0022834	ligand-gated channel activity	11/1691	188/18639	0.0585106382978723	0.644931867081042	0.960044436486408	0.994927121755357
GO:0030332	cyclin binding	1/1691	34/18639	0.0294117647058824	0.324190350297422	0.960703584397679	0.994927121755357
GO:0010485	histone H4 acetyltransferase activity	1/1691	35/18639	0.0285714285714286	0.314927768860353	0.964275217764168	0.99693483563933
GO:0034061	DNA polymerase activity	1/1691	35/18639	0.0285714285714286	0.314927768860353	0.964275217764168	0.99693483563933
GO:0019787	ubiquitin-like protein transferase activity	33/1691	479/18639	0.0688935281837161	0.759376979193545	0.965389152064985	0.997242093630581
GO:0004521	RNA endonuclease activity	3/1691	73/18639	0.0410958904109589	0.45297829767585	0.966978714781081	0.997757476576773
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/1691	36/18639	0.0277777777777778	0.306179775280899	0.967522401528992	0.997757476576773
GO:0003678	DNA helicase activity	3/1691	74/18639	0.0405405405405405	0.446856969328879	0.969262592058003	0.99870854422179
GO:0030551	cyclic nucleotide binding	1/1691	37/18639	0.027027027027027	0.297904646219253	0.970474593058019	0.998746694675256
GO:0008408	3'-5' exonuclease activity	2/1691	58/18639	0.0344827586206897	0.380085238279737	0.972871030687154	0.998746694675256
GO:0000146	microfilament motor activity	1/1691	38/18639	0.0263157894736842	0.290065050266115	0.973158576669399	0.998746694675256
GO:0051536	iron-sulfur cluster binding	3/1691	76/18639	0.0394736842105263	0.435097575399172	0.97338948948694	0.998746694675256
GO:0140034	methylation-dependent protein binding	3/1691	76/18639	0.0394736842105263	0.435097575399172	0.97338948948694	0.998746694675256
GO:0031593	polyubiquitin modification-dependent protein binding	2/1691	59/18639	0.0338983050847458	0.373643115597029	0.974975980583435	0.998846720046698
GO:0051540	metal cluster binding	3/1691	77/18639	0.038961038961039	0.429446957536845	0.975250231370637	0.998846720046698
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/1691	60/18639	0.0333333333333333	0.367415730337079	0.976922574820089	0.998846720046698
GO:0015370	solute:sodium symporter activity	3/1691	79/18639	0.0379746835443038	0.418574882662495	0.978607113135258	0.998846720046698
GO:0016407	acetyltransferase activity	4/1691	96/18639	0.0416666666666667	0.459269662921348	0.978796071022379	0.998846720046698
GO:0140030	modification-dependent protein binding	9/1691	173/18639	0.0520231213872832	0.573423394167695	0.979252847775657	0.998846720046698
GO:0015175	neutral L-amino acid transmembrane transporter activity	1/1691	41/18639	0.024390243902439	0.268840778295423	0.979833966648796	0.998846720046698
GO:0000049	tRNA binding	3/1691	80/18639	0.0375	0.413342696629213	0.980118256883275	0.998846720046698
GO:0004402	histone acetyltransferase activity	1/1691	42/18639	0.0238095238095238	0.262439807383628	0.981667538129433	0.998846720046698
GO:0004520	DNA endonuclease activity	1/1691	42/18639	0.0238095238095238	0.262439807383628	0.981667538129433	0.998846720046698
GO:0015294	solute:monoatomic cation symporter activity	5/1691	116/18639	0.0431034482758621	0.475106547849671	0.983420411122308	0.999471788467573
GO:0051539	4 iron, 4 sulfur cluster binding	1/1691	45/18639	0.0222222222222222	0.244943820224719	0.98622766103919	0.999471788467573
GO:0016779	nucleotidyltransferase activity	6/1691	136/18639	0.0441176470588235	0.486285525446134	0.987150266995081	0.999471788467573
GO:0099094	ligand-gated monoatomic cation channel activity	6/1691	136/18639	0.0441176470588235	0.486285525446134	0.987150266995081	0.999471788467573
GO:0016874	ligase activity	8/1691	167/18639	0.0479041916167665	0.528022606472448	0.987199601616608	0.999471788467573
GO:0004540	RNA nuclease activity	5/1691	121/18639	0.0413223140495868	0.455474045872412	0.988005537664242	0.999471788467573
GO:0140223	general transcription initiation factor activity	2/1691	68/18639	0.0294117647058824	0.324190350297422	0.988011833481048	0.999471788467573
GO:0140299	molecular sensor activity	2/1691	71/18639	0.028169014084507	0.310492166482038	0.990649844761035	0.99989898135623
GO:0005272	sodium channel activity	1/1691	51/18639	0.0196078431372549	0.216126900198282	0.992228256920408	0.99989898135623
GO:0031491	nucleosome binding	2/1691	74/18639	0.027027027027027	0.297904646219253	0.992717708196688	0.99989898135623
GO:0035064	methylated histone binding	2/1691	74/18639	0.027027027027027	0.297904646219253	0.992717708196688	0.99989898135623
GO:0015293	symporter activity	6/1691	146/18639	0.0410958904109589	0.45297829767585	0.993142688211051	0.99989898135623
GO:0004518	nuclease activity	10/1691	209/18639	0.0478468899521531	0.527391000483845	0.99334763667904	0.99989898135623
GO:0140097	catalytic activity, acting on DNA	18/1691	336/18639	0.0535714285714286	0.590489566613162	0.996030140300779	0.999999999869732
GO:0004519	endonuclease activity	4/1691	127/18639	0.031496062992126	0.347164469609838	0.997646545320072	0.999999999869732
GO:0004536	DNA nuclease activity	1/1691	64/18639	0.015625	0.172226123595506	0.997751793539651	0.999999999869732
GO:0003730	mRNA 3'-UTR binding	12/1691	262/18639	0.0458015267175573	0.504846041684536	0.998089598684014	0.999999999869732
GO:0140098	catalytic activity, acting on RNA	18/1691	387/18639	0.0465116279069767	0.512673112098249	0.999693778769097	0.999999999869732
GO:0140101	catalytic activity, acting on a tRNA	3/1691	139/18639	0.0215827338129496	0.23789507719667	0.999807058277578	0.999999999869732
GO:0045182	translation regulator activity	8/1691	356/18639	0.0224719101123595	0.247695997980053	0.999999973566907	0.999999999869732
GO:0030371	translation repressor activity	4/1691	329/18639	0.0121580547112462	0.13401181653632	0.999999999869732	0.999999999869732