category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: bacterial hsa05133 Pertussis 2/11 78/9376 21.8554778554779 C3/FOS 6.33870828540296 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/11 78/9376 21.8554778554779 C3/FOS 6.33870828540296 Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/11 82/9376 20.7893569844789 KIR2DL4/KIR3DL1 6.16829825513433 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 2/11 103/9376 16.5507502206531 C3/FOS 5.43861001492463 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 2/11 133/9376 12.8174982911825 KIR2DL4/KIR3DL1 4.70406140334133 Cellular Processes Transport and catabolism hsa04145 Phagosome 2/11 155/9376 10.9982404692082 C3/TUBB2B 4.30158496803958 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 2/11 157/9376 10.8581354950782 COX6A2/FOS 4.26904557928678 Metabolism Glycan biosynthesis and metabolism hsa00533 Glycosaminoglycan biosynthesis - keratan sulfate 1/11 14/9376 60.8831168831169 B3GNT7 7.68443933529855 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 2/11 196/9376 8.69758812615955 C3/FOS 3.73241094801688 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 2/11 200/9376 8.52363636363636 FOS/TUBB2B 3.68590537820396 NA NA hsa04382 Cornified envelope formation 2/11 217/9376 7.85588604943444 KRT81/KRT86 3.50184982758752 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 2/11 227/9376 7.50981177412895 COX6A2/FOS 3.4026919700253 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 2/11 238/9376 7.16271963330787 C3/FOS 3.30037586074006 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 2/11 248/9376 6.87390029325513 FOS/TUBB2B 3.21286653455775 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 2/11 268/9376 6.36092265943012 COX6A2/TUBB2B 3.05157127246781 Human Diseases Neurodegenerative disease hsa05020 Prion disease 2/11 275/9376 6.19900826446281 COX6A2/TUBB2B 2.99895802683829 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 2/11 308/9376 5.53482880755608 COX6A2/TUBB2B 2.77337495467117 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/11 45/9376 18.9414141414141 KIR3DL1 4.13453738496827 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/11 56/9376 15.2207792207792 C3 3.65794811652283 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 2/11 368/9376 4.63241106719368 COX6A2/TUBB2B 2.43631141878934 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 2/11 388/9376 4.39362699156514 COX6A2/TUBB2B 2.33978809131625 Human Diseases Substance dependence hsa05031 Amphetamine addiction 1/11 69/9376 12.3530961791831 FOS 3.24385994713873 NA NA hsa04519 Cadherin signaling 2/11 404/9376 4.21962196219622 KRT81/KRT86 2.26714355922339 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/11 71/9376 12.0051216389245 FOS 3.19002379602898 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 1/11 87/9376 9.79728317659352 COX6A2 2.82521697200209 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/11 87/9376 9.79728317659352 FOS 2.82521697200209 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/11 88/9376 9.68595041322314 C3 2.80559945393494 Cellular Processes Cellular community - eukaryotes hsa04540 Gap junction 1/11 89/9376 9.57711950970378 TUBB2B 2.78629330783551 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/11 90/9376 9.47070707070707 FOS 2.76728996649894 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/11 91/9376 9.36663336663337 FOS 2.74858119135017 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/11 93/9376 9.16520039100684 FOS 2.7120159329985 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/11 94/9376 9.06769825918762 FOS 2.6941444758583 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 2/11 480/9376 3.55151515151515 COX6A2/TUBB2B 1.96675142321903 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/11 95/9376 8.97224880382775 FOS 2.67653760938949 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/11 97/9376 8.78725398313027 FOS 2.64209062008697 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/11 99/9376 8.60973370064279 FOS 2.60862329381185 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/11 99/9376 8.60973370064279 C3 2.60862329381185 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 1/11 99/9376 8.60973370064279 FOS 2.60862329381185 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/11 100/9376 8.52363636363636 XCL1 2.59224184429779 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/11 109/9376 7.81984987489575 FOS 2.45440694999757 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/11 109/9376 7.81984987489575 FOS 2.45440694999757 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/11 115/9376 7.41185770750988 FOS 2.37100212868794 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 1/11 115/9376 7.41185770750988 FOS 2.37100212868794 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/11 119/9376 7.16271963330787 FOS 2.3186694991625 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/11 122/9376 6.9865871833085 FOS 2.28098573489392 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/11 122/9376 6.9865871833085 FOS 2.28098573489392 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/11 130/9376 6.55664335664336 FOS 2.1864288274848 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 1/11 133/9376 6.40874914559125 FOS 2.1530012079727 Human Diseases Infectious disease: viral hsa05162 Measles 1/11 136/9376 6.26737967914438 FOS 2.1205874285638 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/11 137/9376 6.22163238221632 FOS 2.10999867677426 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 1/11 138/9376 6.17654808959157 COX6A2 2.09951463878002 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/11 138/9376 6.17654808959157 FOS 2.09951463878002 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/11 139/9376 6.13211249182472 FOS 2.08913346268626 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 1/11 142/9376 6.00256081946223 FOS 2.05858926803486 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/11 142/9376 6.00256081946223 FOS 2.05858926803486 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/11 143/9376 5.96058486967578 C3 2.04860191884508 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/11 144/9376 5.91919191919192 C3 2.03870883354416 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/11 148/9376 5.75921375921376 FOS 2.00004775860839 NA NA hsa04518 Integrin signaling 1/11 154/9376 5.53482880755608 C3 1.94462913519421 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/11 154/9376 5.53482880755608 FOS 1.94462913519421 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/11 157/9376 5.42906774753909 KIR2DL4 1.91799880387457 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 1/11 163/9376 5.22922476296709 FOS 1.86673264750151 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/11 178/9376 4.78855975485189 WIF1 1.74890222383545 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/11 180/9376 4.73535353535354 C3 1.73418958397602 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/11 181/9376 4.70919136112506 C3 1.7269141585414 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/11 193/9376 4.41639189825718 XCL1 1.6435470287073 Cellular Processes Cell motility hsa04814 Motor proteins 1/11 194/9376 4.39362699156514 TUBB2B 1.63690854595342 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/11 195/9376 4.37109557109557 C3 1.63031478434278 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 1/11 205/9376 4.15787139689579 C3 1.56671901091872 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/11 205/9376 4.15787139689579 COX6A2 1.56671901091872 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/11 214/9376 3.98300764655905 FOS 1.51284418229144 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/11 216/9376 3.94612794612795 FOS 1.50127009065797 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/11 217/9376 3.92794302471722 FOS 1.49553488817655 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/11 224/9376 3.8051948051948 FOS 1.45632102449449 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 1/11 226/9376 3.77152051488335 FOS 1.44540602292361 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 1/11 235/9376 3.62707930367505 COX6A2 1.39777847926637 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/11 253/9376 3.36902623068631 C3 1.30914991687432 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/11 298/9376 2.86028065893838 XCL1 1.11845780249808 NA NA hsa04517 IgSF CAM signaling 1/11 299/9376 2.85071450288842 TUBB2B 1.11463312301911 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/11 300/9376 2.84121212121212 FOS 1.11082411413931 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/11 370/9376 2.3036855036855 C3 0.876871221689005