category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 2/7 227/9376 11.8011327879169 CCL3L3/HLA-C 4.50280830890614 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 2/7 298/9376 8.98945349952061 CCL3L3/TNFSF9 3.83105295389911 Human Diseases Immune disease hsa05340 Primary immunodeficiency 1/7 38/9376 35.2481203007519 ORAI1 5.78215384341576 Human Diseases Immune disease hsa05330 Allograft rejection 1/7 39/9376 34.3443223443223 HLA-C 5.70346208114058 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/7 44/9376 30.4415584415584 HLA-C 5.35041916273532 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/7 45/9376 29.7650793650794 HLA-C 5.28683525638274 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/7 54/9376 24.8042328042328 HLA-C 4.79495524959245 Organismal Systems Endocrine system hsa04927 Cortisol synthesis and secretion 1/7 65/9376 20.6065934065934 ORAI1 4.33559489690771 Organismal Systems Endocrine system hsa04924 Renin secretion 1/7 69/9376 19.4120082815735 ORAI1 4.19574309681397 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/7 70/9376 19.134693877551 HLA-C 4.16261038629487 Organismal Systems Immune system hsa04612 Antigen processing and presentation 1/7 82/9376 16.3344947735192 HLA-C 3.81208962514015 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/7 95/9376 14.0992481203008 CCL3L3 3.50750923751324 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 1/7 98/9376 13.667638483965 ORAI1 3.44563724516159 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/7 100/9376 13.3942857142857 CCL3L3 3.40587866491184 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/7 103/9376 13.004160887656 CCL3L3 3.34833057568948 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/7 109/9376 12.2883355176933 CCL3L3 3.24012388374589 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 1/7 122/9376 10.9789227166276 DIO2 3.03240263720604 Organismal Systems Immune system hsa04611 Platelet activation 1/7 126/9376 10.6303854875283 ORAI1 2.97472015807397 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/7 133/9376 10.0708915145005 HLA-C 2.87976703259153 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 1/7 138/9376 9.70600414078675 MT-ND4 2.81616095170918 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 1/7 149/9376 8.98945349952061 MT-ND4 2.68700197737182 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/7 155/9376 8.64147465437788 HLA-C 2.62205654918304 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 1/7 155/9376 8.64147465437788 ORAI1 2.62205654918304 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/7 157/9376 8.53139217470428 HLA-C 2.60118487592619 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/7 160/9376 8.37142857142857 HLA-C 2.5705642222751 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/7 180/9376 7.44126984126984 HLA-C 2.38504349357811 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/7 193/9376 6.940044411547 CCL3L3 2.27910373649617 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/7 196/9376 6.83381924198251 HLA-C 2.25604471111744 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/7 205/9376 6.53379790940767 HLA-C 2.18967629841921 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 1/7 205/9376 6.53379790940767 HLA-C 2.18967629841921 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/7 205/9376 6.53379790940767 MT-ND4 2.18967629841921 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/7 214/9376 6.25901201602136 HLA-C 2.12717854892552 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/7 216/9376 6.2010582010582 CCL3L3 2.1137756522795 NA NA hsa04081 Hormone signaling 1/7 219/9376 6.11611219830398 DIO2 2.09398491742935 Genetic Information Processing Translation hsa03010 Ribosome 1/7 222/9376 6.03346203346203 RPS3A 2.07455937490215 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/7 224/9376 5.97959183673469 HLA-C 2.06180594952119 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 1/7 226/9376 5.92667509481669 ORAI1 2.04920606965921 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/7 227/9376 5.90056639395846 MT-ND4 2.04296266978105 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 1/7 235/9376 5.69969604863222 MT-ND4 1.99432019191209 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/7 238/9376 5.62785114045618 RPS3A 1.9766524786679 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/7 250/9376 5.35771428571429 HLA-C 1.90887092525785 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/7 254/9376 5.27334083239595 ORAI1 1.88724114217694 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 1/7 268/9376 4.99786780383795 MT-ND4 1.81498213300361 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/7 275/9376 4.87064935064935 MT-ND4 1.78071188785521 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/7 308/9376 4.34879406307978 MT-ND4 1.63341328051133 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/7 333/9376 4.02230802230802 HLA-C 1.53494427720998 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 1/7 368/9376 3.63975155279503 MT-ND4 1.41208491421099 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/7 388/9376 3.45213549337261 MT-ND4 1.34839406787352 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 1/7 480/9376 2.79047619047619 MT-ND4 1.10072750937098