ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0046975 histone H3K36 methyltransferase activity 5/192 13/18639 0.384615384615385 37.3377403846154 1.32510039395369e-07 7.27480116280577e-05 GO:0140297 DNA-binding transcription factor binding 17/192 488/18639 0.0348360655737705 3.38181992827869 1.26914160224044e-05 0.00348379369815 GO:0001221 transcription coregulator binding 8/192 115/18639 0.0695652173913043 6.75326086956522 2.53054972061471e-05 0.00382569437462672 GO:0004879 nuclear receptor activity 6/192 59/18639 0.101694915254237 9.87235169491525 3.16267247599722e-05 0.00382569437462672 GO:0098531 ligand-modulated transcription factor activity 6/192 60/18639 0.1 9.7078125 3.48423895685494e-05 0.00382569437462672 GO:0140938 histone H3 methyltransferase activity 5/192 47/18639 0.106382978723404 10.327460106383 0.000118874223533754 0.0108769914533385 GO:0003714 transcription corepressor activity 9/192 204/18639 0.0441176470588235 4.28285845588235 0.000272267007851331 0.0191493332244926 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 12/192 349/18639 0.0343839541547278 3.33792979942693 0.000279043107096431 0.0191493332244926 GO:0008170 N-methyltransferase activity 6/192 98/18639 0.0612244897959184 5.94355867346939 0.00053032616973983 0.0323498963541296 GO:0042054 histone methyltransferase activity 5/192 67/18639 0.0746268656716418 7.24463619402985 0.000633852249708662 0.0347984885090055 GO:0016279 protein-lysine N-methyltransferase activity 5/192 69/18639 0.072463768115942 7.03464673913043 0.000725482704728226 0.0354490708552243 GO:0016278 lysine N-methyltransferase activity 5/192 70/18639 0.0714285714285714 6.93415178571429 0.000774843078802716 0.0354490708552243 GO:0019209 kinase activator activity 7/192 148/18639 0.0472972972972973 4.59153293918919 0.000868943246587951 0.0366961417212912 GO:0001223 transcription coactivator binding 4/192 44/18639 0.0909090909090909 8.82528409090909 0.00107350392758387 0.0420966897316818 GO:0008168 methyltransferase activity 8/192 204/18639 0.0392156862745098 3.80698529411765 0.00127539575285009 0.0466794845543132 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 7/192 167/18639 0.0419161676646707 4.06914296407186 0.00174818353748984 0.0574038099338331 GO:0016741 transferase activity, transferring one-carbon groups 8/192 215/18639 0.0372093023255814 3.61220930232558 0.00177753145514601 0.0574038099338331 GO:0003712 transcription coregulator activity 13/192 495/18639 0.0262626262626263 2.54952651515151 0.00191537860373265 0.0584190474138458 GO:0008276 protein methyltransferase activity 5/192 95/18639 0.0526315789473684 5.109375 0.00301735705536161 0.084393951288437 GO:0030295 protein kinase activator activity 6/192 139/18639 0.0431654676258993 4.1904226618705 0.00319998536251547 0.084393951288437 GO:0106222 lncRNA binding 3/192 29/18639 0.103448275862069 10.0425646551724 0.0032281839290659 0.084393951288437 GO:0042393 histone binding 8/192 247/18639 0.0323886639676113 3.14423076923077 0.00416077455106824 0.103830237660748 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 12/192 484/18639 0.0247933884297521 2.40689566115703 0.00449305988069309 0.106988581709559 GO:0030296 protein tyrosine kinase activator activity 3/192 33/18639 0.0909090909090909 8.82528409090909 0.00467709646817742 0.106988581709559 GO:0001216 DNA-binding transcription activator activity 12/192 491/18639 0.0244399185336049 2.37258146639511 0.0050271807725513 0.11014907112546 GO:0005496 steroid binding 5/192 108/18639 0.0462962962962963 4.49435763888889 0.00521653160157006 0.11014907112546 GO:0034056 estrogen response element binding 2/192 11/18639 0.181818181818182 17.6505681818182 0.00546143829247953 0.111049245280417 GO:0005518 collagen binding 4/192 72/18639 0.0555555555555556 5.39322916666667 0.00650879364605156 0.123231803465528 GO:0035497 cAMP response element binding 2/192 12/18639 0.166666666666667 16.1796875 0.00650951238706794 0.123231803465528 GO:0031994 insulin-like growth factor I binding 2/192 13/18639 0.153846153846154 14.9350961538462 0.00764120345615689 0.135323248304198 GO:0046974 histone H3K9 methyltransferase activity 2/192 13/18639 0.153846153846154 14.9350961538462 0.00764120345615689 0.135323248304198 GO:0048156 tau protein binding 3/192 43/18639 0.0697674418604651 6.77289244186046 0.00981406762816204 0.163863623137233 GO:0019207 kinase regulator activity 8/192 287/18639 0.0278745644599303 2.70601045296167 0.00995496924316491 0.163863623137233 GO:0061578 K63-linked deubiquitinase activity 2/192 15/18639 0.133333333333333 12.94375 0.0101482025258031 0.163863623137233 GO:0031490 chromatin DNA binding 5/192 128/18639 0.0390625 3.7921142578125 0.0105111218760525 0.164874454570081 GO:0005159 insulin-like growth factor receptor binding 2/192 16/18639 0.125 12.134765625 0.0115199636259514 0.16531999825108 GO:0008142 oxysterol binding 2/192 16/18639 0.125 12.134765625 0.0115199636259514 0.16531999825108 GO:0061749 forked DNA-dependent helicase activity 3/192 47/18639 0.0638297872340425 6.19647606382979 0.0125147258373795 0.16531999825108 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/192 47/18639 0.0638297872340425 6.19647606382979 0.0125147258373795 0.16531999825108 GO:0046965 nuclear retinoid X receptor binding 2/192 17/18639 0.117647058823529 11.4209558823529 0.0129682471382552 0.16531999825108 GO:1990226 histone methyltransferase binding 2/192 17/18639 0.117647058823529 11.4209558823529 0.0129682471382552 0.16531999825108 GO:0009378 four-way junction helicase activity 3/192 48/18639 0.0625 6.0673828125 0.0132496902059153 0.16531999825108 GO:0036121 double-stranded DNA helicase activity 3/192 48/18639 0.0625 6.0673828125 0.0132496902059153 0.16531999825108 GO:0043138 3'-5' DNA helicase activity 3/192 48/18639 0.0625 6.0673828125 0.0132496902059153 0.16531999825108 GO:0005021 vascular endothelial growth factor receptor activity 3/192 51/18639 0.0588235294117647 5.71047794117647 0.0155999160483774 0.184001786016229 GO:0005520 insulin-like growth factor binding 2/192 19/18639 0.105263157894737 10.21875 0.0160875878484135 0.184001786016229 GO:0042800 histone H3K4 methyltransferase activity 2/192 19/18639 0.105263157894737 10.21875 0.0160875878484135 0.184001786016229 GO:1990380 K48-linked deubiquitinase activity 2/192 19/18639 0.105263157894737 10.21875 0.0160875878484135 0.184001786016229 GO:0019887 protein kinase regulator activity 7/192 255/18639 0.0274509803921569 2.66488970588235 0.0167212223752657 0.184207069234026 GO:0003779 actin binding 10/192 443/18639 0.0225733634311512 2.19137979683973 0.0167766001123885 0.184207069234026 GO:0043024 ribosomal small subunit binding 2/192 20/18639 0.1 9.7078125 0.0177553146255849 0.191130739793061 GO:0072542 protein phosphatase activator activity 2/192 21/18639 0.0952380952380952 9.24553571428571 0.0194929022497998 0.205800064137309 GO:0050321 tau-protein kinase activity 2/192 22/18639 0.0909090909090909 8.82528409090909 0.0212987502450723 0.220622903481975 GO:0017116 single-stranded DNA helicase activity 3/192 58/18639 0.0517241379310345 5.02128232758621 0.0219406959420004 0.223063742077004 GO:0005158 insulin receptor binding 2/192 23/18639 0.0869565217391304 8.44157608695652 0.023171283393719 0.22452523245571 GO:0044013 histone H2B acetyltransferase activity 2/192 23/18639 0.0869565217391304 8.44157608695652 0.023171283393719 0.22452523245571 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/192 60/18639 0.05 4.85390625 0.0239740622321113 0.22452523245571 GO:0008013 beta-catenin binding 4/192 106/18639 0.0377358490566038 3.66332547169811 0.0240410804821211 0.22452523245571 GO:0015026 coreceptor activity 3/192 61/18639 0.0491803278688525 4.77433401639344 0.0250277324768938 0.22452523245571 GO:0019211 phosphatase activator activity 2/192 25/18639 0.08 7.76625 0.0271102284998689 0.22452523245571 GO:0042974 nuclear retinoic acid receptor binding 2/192 25/18639 0.08 7.76625 0.0271102284998689 0.22452523245571 GO:0043022 ribosome binding 4/192 112/18639 0.0357142857142857 3.46707589285714 0.0286789853736078 0.22452523245571 GO:0141003 histone H2AX kinase activity 8/192 354/18639 0.0225988700564972 2.19385593220339 0.0306445502229467 0.22452523245571 GO:0008266 poly(U) RNA binding 2/192 27/18639 0.0740740740740741 7.19097222222222 0.0312976279514123 0.22452523245571 GO:0050840 extracellular matrix binding 3/192 67/18639 0.0447761194029851 4.34678171641791 0.0318658453236652 0.22452523245571 GO:0140996 histone H3 kinase activity 8/192 357/18639 0.0224089635854342 2.17542016806723 0.0319802527463368 0.22452523245571 GO:0019208 phosphatase regulator activity 4/192 117/18639 0.0341880341880342 3.31891025641026 0.0329229560301477 0.22452523245571 GO:0032934 sterol binding 3/192 68/18639 0.0441176470588235 4.28285845588235 0.0330911080589041 0.22452523245571 GO:1990841 promoter-specific chromatin binding 3/192 68/18639 0.0441176470588235 4.28285845588235 0.0330911080589041 0.22452523245571 GO:0035173 histone kinase activity 8/192 360/18639 0.0222222222222222 2.15729166666667 0.033355341400557 0.22452523245571 GO:0046966 nuclear thyroid hormone receptor binding 2/192 28/18639 0.0714285714285714 6.93415178571429 0.0334808186615752 0.22452523245571 GO:0106310 protein serine kinase activity 8/192 361/18639 0.0221606648199446 2.15131578947368 0.0338225344240171 0.22452523245571 GO:0004674 protein serine/threonine kinase activity 9/192 433/18639 0.0207852193995381 2.01779012702079 0.0357929299096775 0.22452523245571 GO:0043021 ribonucleoprotein complex binding 5/192 177/18639 0.0282485875706215 2.74231991525424 0.036513052076046 0.22452523245571 GO:0001968 fibronectin binding 2/192 30/18639 0.0666666666666667 6.471875 0.0380190278123458 0.22452523245571 GO:0008187 poly-pyrimidine tract binding 2/192 30/18639 0.0666666666666667 6.471875 0.0380190278123458 0.22452523245571 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/192 30/18639 0.0666666666666667 6.471875 0.0380190278123458 0.22452523245571 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 6/192 243/18639 0.0246913580246914 2.39699074074074 0.0402806864829711 0.22452523245571 GO:0008327 methyl-CpG binding 2/192 31/18639 0.0645161290322581 6.26310483870968 0.0403712531478825 0.22452523245571 GO:0070273 phosphatidylinositol-4-phosphate binding 2/192 31/18639 0.0645161290322581 6.26310483870968 0.0403712531478825 0.22452523245571 GO:0003678 DNA helicase activity 3/192 74/18639 0.0405405405405405 3.93559966216216 0.0409496137070956 0.22452523245571 GO:0004676 3-phosphoinositide-dependent protein kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0004711 ribosomal protein S6 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0035175 histone H3S10 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0035979 histone H2AXS139 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0044022 histone H3S28 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0044023 histone H4S1 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0044024 histone H2AS1 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0044025 histone H2BS14 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0072354 histone H3T3 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0072371 histone H2AS121 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0072518 Rho-dependent protein serine/threonine kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0140823 histone H2BS36 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0140855 histone H3S57 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0140995 histone H2A kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0140997 histone H4 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0140998 histone H2B kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:1990244 histone H2AT120 kinase activity 6/192 245/18639 0.0244897959183673 2.37742346938776 0.0416418029044883 0.22452523245571 GO:0004677 DNA-dependent protein kinase activity 6/192 246/18639 0.024390243902439 2.36775914634146 0.0423331390516816 0.22452523245571 GO:0140857 histone H3T45 kinase activity 6/192 246/18639 0.024390243902439 2.36775914634146 0.0423331390516816 0.22452523245571 GO:0003725 double-stranded RNA binding 3/192 75/18639 0.04 3.883125 0.0423429704340667 0.22452523245571 GO:0070717 poly-purine tract binding 2/192 32/18639 0.0625 6.0673828125 0.0427770676239634 0.22452523245571 GO:1901981 phosphatidylinositol phosphate binding 5/192 185/18639 0.027027027027027 2.62373310810811 0.0428124262935322 0.22452523245571 GO:0035402 histone H3T11 kinase activity 6/192 247/18639 0.0242914979757085 2.35817307692308 0.0430316820611343 0.22452523245571 GO:0035403 histone H3T6 kinase activity 6/192 247/18639 0.0242914979757085 2.35817307692308 0.0430316820611343 0.22452523245571 GO:0004679 AMP-activated protein kinase activity 6/192 248/18639 0.0241935483870968 2.34866431451613 0.0437374473879188 0.22452523245571 GO:0098631 cell adhesion mediator activity 3/192 76/18639 0.0394736842105263 3.83203125 0.0437599269084899 0.22452523245571 GO:0019199 transmembrane receptor protein kinase activity 3/192 78/18639 0.0384615384615385 3.73377403846154 0.0466641525241598 0.237209441997812 GO:0010485 histone H4 acetyltransferase activity 2/192 35/18639 0.0571428571428571 5.54732142857143 0.0503027444029573 0.253359694286455 GO:0019838 growth factor binding 4/192 136/18639 0.0294117647058824 2.85523897058824 0.0522360028643769 0.260705141568572 GO:0016922 nuclear receptor binding 4/192 137/18639 0.0291970802919708 2.83439781021898 0.0533922358870443 0.264075112630516 GO:0051117 ATPase binding 3/192 84/18639 0.0357142857142857 3.46707589285714 0.0559296791556629 0.274155302289812 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 6/192 268/18639 0.0223880597014925 2.17339085820896 0.0593880894679778 0.288531514317875 GO:0005516 calmodulin binding 5/192 207/18639 0.0241545893719807 2.34488224637681 0.0633268399569161 0.304158221700685 GO:0030331 nuclear estrogen receptor binding 2/192 40/18639 0.05 4.85390625 0.0637963559072093 0.304158221700685 GO:0003727 single-stranded RNA binding 3/192 89/18639 0.0337078651685393 3.27229634831461 0.0642665823629864 0.304158221700685 GO:0051015 actin filament binding 5/192 209/18639 0.0239234449760766 2.32244318181818 0.0654247439332014 0.306993029225022 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/192 41/18639 0.0487804878048781 4.73551829268293 0.0666266693514163 0.30998340232142 GO:0001217 DNA-binding transcription repressor activity 6/192 278/18639 0.0215827338129496 2.09521133093525 0.0683216300114827 0.315198108204235 GO:0004402 histone acetyltransferase activity 2/192 42/18639 0.0476190476190476 4.62276785714286 0.0694981028457697 0.315326102994443 GO:0031492 nucleosomal DNA binding 2/192 42/18639 0.0476190476190476 4.62276785714286 0.0694981028457697 0.315326102994443 GO:0016410 N-acyltransferase activity 3/192 94/18639 0.0319148936170213 3.09823803191489 0.0731408406537221 0.328420470109749 GO:0035091 phosphatidylinositol binding 6/192 284/18639 0.0211267605633803 2.0509463028169 0.074037597287741 0.328420470109749 GO:0004867 serine-type endopeptidase inhibitor activity 3/192 95/18639 0.0315789473684211 3.065625 0.074978176505692 0.328420470109749 GO:0003954 NADH dehydrogenase activity 2/192 44/18639 0.0454545454545455 4.41264204545455 0.0753598000610949 0.328420470109749 GO:0016407 acetyltransferase activity 3/192 96/18639 0.03125 3.03369140625 0.0768358961625593 0.328420470109749 GO:0061733 protein-lysine-acetyltransferase activity 2/192 47/18639 0.0425531914893617 4.13098404255319 0.0844329234153741 0.328420470109749 GO:0004866 endopeptidase inhibitor activity 4/192 161/18639 0.0248447204968944 2.41187888198758 0.0852196149125264 0.328420470109749 GO:0005178 integrin binding 4/192 161/18639 0.0248447204968944 2.41187888198758 0.0852196149125264 0.328420470109749 GO:0140693 molecular condensate scaffold activity 2/192 48/18639 0.0416666666666667 4.044921875 0.0875278465983941 0.328420470109749 GO:0001222 transcription corepressor binding 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0005004 GPI-linked ephrin receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0005008 hepatocyte growth factor receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0005009 insulin receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0005011 macrophage colony-stimulating factor receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0005020 stem cell factor receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0008288 boss receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0036332 placental growth factor receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0038062 protein tyrosine kinase collagen receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0060175 brain-derived neurotrophic factor receptor activity 2/192 49/18639 0.0408163265306122 3.96237244897959 0.0906563161181411 0.328420470109749 GO:0005006 epidermal growth factor receptor activity 2/192 50/18639 0.04 3.883125 0.0938173212721262 0.328420470109749 GO:0005007 fibroblast growth factor receptor activity 2/192 50/18639 0.04 3.883125 0.0938173212721262 0.328420470109749 GO:0005017 platelet-derived growth factor receptor activity 2/192 50/18639 0.04 3.883125 0.0938173212721262 0.328420470109749 GO:0005019 platelet-derived growth factor beta-receptor activity 2/192 50/18639 0.04 3.883125 0.0938173212721262 0.328420470109749 GO:0003743 translation initiation factor activity 2/192 51/18639 0.0392156862745098 3.80698529411765 0.0970098684241159 0.328420470109749 GO:0005010 insulin-like growth factor receptor activity 2/192 51/18639 0.0392156862745098 3.80698529411765 0.0970098684241159 0.328420470109749 GO:0005030 neurotrophin receptor activity 2/192 51/18639 0.0392156862745098 3.80698529411765 0.0970098684241159 0.328420470109749 GO:0030414 peptidase inhibitor activity 4/192 169/18639 0.0236686390532544 2.29770710059172 0.0974978568559983 0.328420470109749 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/192 10/18639 0.1 9.7078125 0.0983863513528933 0.328420470109749 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/192 10/18639 0.1 9.7078125 0.0983863513528933 0.328420470109749 GO:0005031 tumor necrosis factor receptor activity 1/192 10/18639 0.1 9.7078125 0.0983863513528933 0.328420470109749 GO:0005381 iron ion transmembrane transporter activity 1/192 10/18639 0.1 9.7078125 0.0983863513528933 0.328420470109749 GO:0008140 cAMP response element binding protein binding 1/192 10/18639 0.1 9.7078125 0.0983863513528933 0.328420470109749 GO:0015643 toxic substance binding 1/192 10/18639 0.1 9.7078125 0.0983863513528933 0.328420470109749 GO:0016427 tRNA (cytidine) methyltransferase activity 1/192 10/18639 0.1 9.7078125 0.0983863513528933 0.328420470109749 GO:0019531 oxalate transmembrane transporter activity 1/192 10/18639 0.1 9.7078125 0.0983863513528933 0.328420470109749 GO:0030957 Tat protein binding 1/192 10/18639 0.1 9.7078125 0.0983863513528933 0.328420470109749 GO:0019888 protein phosphatase regulator activity 3/192 107/18639 0.0280373831775701 2.72181658878505 0.0985586437458787 0.328420470109749 GO:0005080 protein kinase C binding 2/192 52/18639 0.0384615384615385 3.73377403846154 0.100232980762848 0.328420470109749 GO:0008201 heparin binding 4/192 172/18639 0.0232558139534884 2.25763081395349 0.102304985497444 0.328420470109749 GO:0005003 ephrin receptor activity 2/192 53/18639 0.0377358490566038 3.66332547169811 0.103485698063865 0.328420470109749 GO:0005005 transmembrane-ephrin receptor activity 2/192 53/18639 0.0377358490566038 3.66332547169811 0.103485698063865 0.328420470109749 GO:0034212 protein N-acetyltransferase activity 2/192 53/18639 0.0377358490566038 3.66332547169811 0.103485698063865 0.328420470109749 GO:0038064 collagen receptor activity 2/192 53/18639 0.0377358490566038 3.66332547169811 0.103485698063865 0.328420470109749 GO:0140296 general transcription initiation factor binding 2/192 53/18639 0.0377358490566038 3.66332547169811 0.103485698063865 0.328420470109749 GO:0140463 chromatin-protein adaptor activity 2/192 54/18639 0.037037037037037 3.59548611111111 0.106767076454428 0.328420470109749 GO:1902936 phosphatidylinositol bisphosphate binding 3/192 111/18639 0.027027027027027 2.62373310810811 0.107009743921195 0.328420470109749 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0005536 D-glucose binding 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0008046 axon guidance receptor activity 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0035252 UDP-xylosyltransferase activity 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0042285 xylosyltransferase activity 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0043522 leucine zipper domain binding 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0050998 nitric-oxide synthase binding 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0097493 structural molecule activity conferring elasticity 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0140537 transcription regulator activator activity 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0180030 inositol phosphate kinase activity 1/192 11/18639 0.0909090909090909 8.82528409090909 0.107678842658934 0.328420470109749 GO:0005200 structural constituent of cytoskeleton 3/192 112/18639 0.0267857142857143 2.60030691964286 0.109165636358284 0.33111565945137 GO:0098632 cell-cell adhesion mediator activity 2/192 55/18639 0.0363636363636364 3.53011363636364 0.110076188181472 0.332043007206749 GO:0005095 GTPase inhibitor activity 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0005165 neurotrophin receptor binding 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0015269 calcium-activated potassium channel activity 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0016801 hydrolase activity, acting on ether bonds 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0016803 ether hydrolase activity 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0035259 nuclear glucocorticoid receptor binding 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0045295 gamma-catenin binding 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0140900 chloride:bicarbonate antiporter activity 1/192 12/18639 0.0833333333333333 8.08984375 0.116876054501831 0.332460901147696 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/192 58/18639 0.0344827586206897 3.34752155172414 0.120160882856937 0.340042910765248 GO:0061135 endopeptidase regulator activity 4/192 184/18639 0.0217391304347826 2.11039402173913 0.122584724593201 0.344091782869876 GO:0003713 transcription coactivator activity 5/192 256/18639 0.01953125 1.89605712890625 0.125474203428837 0.344091782869876 GO:0005035 death receptor activity 1/192 13/18639 0.0769230769230769 7.46754807692308 0.125978958755638 0.344091782869876 GO:0017154 semaphorin receptor activity 1/192 13/18639 0.0769230769230769 7.46754807692308 0.125978958755638 0.344091782869876 GO:0043560 insulin receptor substrate binding 1/192 13/18639 0.0769230769230769 7.46754807692308 0.125978958755638 0.344091782869876 GO:0097157 pre-mRNA intronic binding 1/192 13/18639 0.0769230769230769 7.46754807692308 0.125978958755638 0.344091782869876 GO:0140666 annealing activity 1/192 13/18639 0.0769230769230769 7.46754807692308 0.125978958755638 0.344091782869876 GO:0005545 1-phosphatidylinositol binding 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0008174 mRNA methyltransferase activity 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0008191 metalloendopeptidase inhibitor activity 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0008474 palmitoyl-(protein) hydrolase activity 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0015926 glucosidase activity 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0032454 histone H3K9 demethylase activity 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0042043 neurexin family protein binding 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0046030 inositol trisphosphate phosphatase activity 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0098599 palmitoyl hydrolase activity 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:1901612 cardiolipin binding 1/192 14/18639 0.0714285714285714 6.93415178571429 0.134988517432698 0.347928150565968 GO:0042826 histone deacetylase binding 3/192 127/18639 0.0236220472440945 2.29318405511811 0.143394934408606 0.362238746123866 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/192 15/18639 0.0666666666666667 6.471875 0.14390568278319 0.362238746123866 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/192 15/18639 0.0666666666666667 6.471875 0.14390568278319 0.362238746123866 GO:0015116 sulfate transmembrane transporter activity 1/192 15/18639 0.0666666666666667 6.471875 0.14390568278319 0.362238746123866 GO:0051371 muscle alpha-actinin binding 1/192 15/18639 0.0666666666666667 6.471875 0.14390568278319 0.362238746123866 GO:0019843 rRNA binding 2/192 65/18639 0.0307692307692308 2.98701923076923 0.14449960910952 0.362238746123866 GO:0005096 GTPase activator activity 5/192 271/18639 0.018450184501845 1.79110931734317 0.14864637155751 0.370940263568513 GO:0008173 RNA methyltransferase activity 2/192 67/18639 0.0298507462686567 2.89785447761194 0.151632053317646 0.371015651190824 GO:0016500 protein-hormone receptor activity 2/192 67/18639 0.0298507462686567 2.89785447761194 0.151632053317646 0.371015651190824 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/192 16/18639 0.0625 6.0673828125 0.152731397393672 0.371015651190824 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/192 16/18639 0.0625 6.0673828125 0.152731397393672 0.371015651190824 GO:0030275 LRR domain binding 1/192 16/18639 0.0625 6.0673828125 0.152731397393672 0.371015651190824 GO:0034450 ubiquitin-ubiquitin ligase activity 1/192 16/18639 0.0625 6.0673828125 0.152731397393672 0.371015651190824 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/192 68/18639 0.0294117647058824 2.85523897058824 0.155224203173972 0.375410077279782 GO:0008080 N-acetyltransferase activity 2/192 69/18639 0.0289855072463768 2.81385869565217 0.158832667375998 0.382452343813257 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/192 17/18639 0.0588235294117647 5.71047794117647 0.161466594284636 0.383745282520629 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/192 17/18639 0.0588235294117647 5.71047794117647 0.161466594284636 0.383745282520629 GO:0038191 neuropilin binding 1/192 17/18639 0.0588235294117647 5.71047794117647 0.161466594284636 0.383745282520629 GO:0097110 scaffold protein binding 2/192 70/18639 0.0285714285714286 2.77366071428571 0.162456734079325 0.384434254351505 GO:0004706 JUN kinase kinase kinase activity 1/192 18/18639 0.0555555555555556 5.39322916666667 0.17011219700708 0.394057367750577 GO:0008409 5'-3' exonuclease activity 1/192 18/18639 0.0555555555555556 5.39322916666667 0.17011219700708 0.394057367750577 GO:0017075 syntaxin-1 binding 1/192 18/18639 0.0555555555555556 5.39322916666667 0.17011219700708 0.394057367750577 GO:0035615 clathrin adaptor activity 1/192 18/18639 0.0555555555555556 5.39322916666667 0.17011219700708 0.394057367750577 GO:1901611 phosphatidylglycerol binding 1/192 18/18639 0.0555555555555556 5.39322916666667 0.17011219700708 0.394057367750577 GO:0043539 protein serine/threonine kinase activator activity 2/192 73/18639 0.0273972602739726 2.65967465753425 0.173415621517032 0.40002174879349 GO:0004713 protein tyrosine kinase activity 3/192 140/18639 0.0214285714285714 2.08024553571429 0.1755299452579 0.403204769650991 GO:0031491 nucleosome binding 2/192 74/18639 0.027027027027027 2.62373310810811 0.177095232845086 0.403424410091088 GO:0035064 methylated histone binding 2/192 74/18639 0.027027027027027 2.62373310810811 0.177095232845086 0.403424410091088 GO:0015245 fatty acid transmembrane transporter activity 1/192 19/18639 0.0526315789473684 5.109375 0.178669119738117 0.403659863112042 GO:0042577 lipid phosphatase activity 1/192 19/18639 0.0526315789473684 5.109375 0.178669119738117 0.403659863112042 GO:0140034 methylation-dependent protein binding 2/192 76/18639 0.0263157894736842 2.5546875 0.184490512103364 0.405586607461424 GO:0019955 cytokine binding 3/192 144/18639 0.0208333333333333 2.0224609375 0.185797133262085 0.405586607461424 GO:0001972 retinoic acid binding 1/192 20/18639 0.05 4.85390625 0.187138267375618 0.405586607461424 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/192 20/18639 0.05 4.85390625 0.187138267375618 0.405586607461424 GO:0052745 inositol phosphate phosphatase activity 1/192 20/18639 0.05 4.85390625 0.187138267375618 0.405586607461424 GO:0061608 nuclear import signal receptor activity 1/192 20/18639 0.05 4.85390625 0.187138267375618 0.405586607461424 GO:0140939 histone H4 methyltransferase activity 1/192 20/18639 0.05 4.85390625 0.187138267375618 0.405586607461424 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/192 21/18639 0.0476190476190476 4.62276785714286 0.195520535631909 0.405586607461424 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/192 21/18639 0.0476190476190476 4.62276785714286 0.195520535631909 0.405586607461424 GO:0010314 phosphatidylinositol-5-phosphate binding 1/192 21/18639 0.0476190476190476 4.62276785714286 0.195520535631909 0.405586607461424 GO:0035613 RNA stem-loop binding 1/192 21/18639 0.0476190476190476 4.62276785714286 0.195520535631909 0.405586607461424 GO:0051010 microtubule plus-end binding 1/192 21/18639 0.0476190476190476 4.62276785714286 0.195520535631909 0.405586607461424 GO:0070182 DNA polymerase binding 1/192 21/18639 0.0476190476190476 4.62276785714286 0.195520535631909 0.405586607461424 GO:0140312 cargo adaptor activity 1/192 21/18639 0.0476190476190476 4.62276785714286 0.195520535631909 0.405586607461424 GO:0000049 tRNA binding 2/192 80/18639 0.025 2.426953125 0.199407844150749 0.405586607461424 GO:0032931 histone H3K56 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0043992 histone H3K9 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0043993 histone H3K18 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0043994 histone H3K23 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0043999 histone H2AK5 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0044012 histone H2AK9 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0044014 histone H2BK5 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0044015 histone H2BK12 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0044016 histone H3K4 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0044017 histone H3K27 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0044018 histone H3K36 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0046972 histone H4K16 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0140908 histone H3K122 acetyltransferase activity 1/192 22/18639 0.0454545454545455 4.41264204545455 0.203816811126521 0.405586607461424 GO:0000510 H3-H4 histone complex chaperone activity 3/192 151/18639 0.0198675496688742 1.92870447019868 0.204126309524606 0.405586607461424 GO:0140584 chromatin extrusion motor activity 3/192 151/18639 0.0198675496688742 1.92870447019868 0.204126309524606 0.405586607461424 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/192 151/18639 0.0198675496688742 1.92870447019868 0.204126309524606 0.405586607461424 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/192 151/18639 0.0198675496688742 1.92870447019868 0.204126309524606 0.405586607461424 GO:0061134 peptidase regulator activity 4/192 226/18639 0.0176991150442478 1.71819690265487 0.204795775121606 0.405586607461424 GO:0015616 DNA translocase activity 3/192 152/18639 0.0197368421052632 1.916015625 0.206778871821613 0.405586607461424 GO:0140674 ATP-dependent histone chaperone activity 3/192 152/18639 0.0197368421052632 1.916015625 0.206778871821613 0.405586607461424 GO:0003774 cytoskeletal motor activity 3/192 153/18639 0.0196078431372549 1.90349264705882 0.209439321833843 0.405586607461424 GO:0061775 cohesin loader activity 3/192 153/18639 0.0196078431372549 1.90349264705882 0.209439321833843 0.405586607461424 GO:0008135 translation factor activity, RNA binding 2/192 83/18639 0.0240963855421687 2.33923192771084 0.210688028684083 0.405586607461424 GO:0030165 PDZ domain binding 2/192 83/18639 0.0240963855421687 2.33923192771084 0.210688028684083 0.405586607461424 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/192 229/18639 0.0174672489082969 1.69568777292576 0.211206117830199 0.405586607461424 GO:0003887 DNA-directed DNA polymerase activity 1/192 23/18639 0.0434782608695652 4.22078804347826 0.212027971478012 0.405586607461424 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/192 23/18639 0.0434782608695652 4.22078804347826 0.212027971478012 0.405586607461424 GO:0070577 lysine-acetylated histone binding 1/192 23/18639 0.0434782608695652 4.22078804347826 0.212027971478012 0.405586607461424 GO:0099186 structural constituent of postsynapse 1/192 23/18639 0.0434782608695652 4.22078804347826 0.212027971478012 0.405586607461424 GO:0180051 translation factor activity 2/192 84/18639 0.0238095238095238 2.31138392857143 0.21446262257502 0.40801346399129 GO:0004386 helicase activity 3/192 155/18639 0.0193548387096774 1.8789314516129 0.214783043886125 0.40801346399129 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/192 24/18639 0.0416666666666667 4.044921875 0.22015488539487 0.409711973158588 GO:0015149 hexose transmembrane transporter activity 1/192 24/18639 0.0416666666666667 4.044921875 0.22015488539487 0.409711973158588 GO:0030215 semaphorin receptor binding 1/192 24/18639 0.0416666666666667 4.044921875 0.22015488539487 0.409711973158588 GO:0043998 histone H2A acetyltransferase activity 1/192 24/18639 0.0416666666666667 4.044921875 0.22015488539487 0.409711973158588 GO:0055056 D-glucose transmembrane transporter activity 1/192 24/18639 0.0416666666666667 4.044921875 0.22015488539487 0.409711973158588 GO:0140033 acetylation-dependent protein binding 1/192 24/18639 0.0416666666666667 4.044921875 0.22015488539487 0.409711973158588 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/192 86/18639 0.0232558139534884 2.25763081395349 0.222030362711895 0.411806314624426 GO:0140658 ATP-dependent chromatin remodeler activity 3/192 158/18639 0.0189873417721519 1.84325553797468 0.222852556996716 0.411939575054536 GO:0003707 nuclear steroid receptor activity 1/192 25/18639 0.04 3.883125 0.228198412765494 0.414222086920955 GO:0004709 MAP kinase kinase kinase activity 1/192 25/18639 0.04 3.883125 0.228198412765494 0.414222086920955 GO:0008139 nuclear localization sequence binding 1/192 25/18639 0.04 3.883125 0.228198412765494 0.414222086920955 GO:0047617 fatty acyl-CoA hydrolase activity 1/192 25/18639 0.04 3.883125 0.228198412765494 0.414222086920955 GO:0003689 DNA clamp loader activity 3/192 160/18639 0.01875 1.82021484375 0.228265782048178 0.414222086920955 GO:0004197 cysteine-type endopeptidase activity 2/192 88/18639 0.0227272727272727 2.20632102272727 0.229619368676509 0.414222086920955 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/192 88/18639 0.0227272727272727 2.20632102272727 0.229619368676509 0.414222086920955 GO:0005227 calcium-activated cation channel activity 1/192 26/18639 0.0384615384615385 3.73377403846154 0.236159404747284 0.414222086920955 GO:0008143 poly(A) binding 1/192 26/18639 0.0384615384615385 3.73377403846154 0.236159404747284 0.414222086920955 GO:0015145 monosaccharide transmembrane transporter activity 1/192 26/18639 0.0384615384615385 3.73377403846154 0.236159404747284 0.414222086920955 GO:0016289 acyl-CoA hydrolase activity 1/192 26/18639 0.0384615384615385 3.73377403846154 0.236159404747284 0.414222086920955 GO:0043548 phosphatidylinositol 3-kinase binding 1/192 26/18639 0.0384615384615385 3.73377403846154 0.236159404747284 0.414222086920955 GO:0050681 nuclear androgen receptor binding 1/192 26/18639 0.0384615384615385 3.73377403846154 0.236159404747284 0.414222086920955 GO:0050750 low-density lipoprotein particle receptor binding 1/192 26/18639 0.0384615384615385 3.73377403846154 0.236159404747284 0.414222086920955 GO:0052742 phosphatidylinositol kinase activity 1/192 26/18639 0.0384615384615385 3.73377403846154 0.236159404747284 0.414222086920955 GO:0070412 R-SMAD binding 1/192 26/18639 0.0384615384615385 3.73377403846154 0.236159404747284 0.414222086920955 GO:0140713 histone chaperone activity 3/192 164/18639 0.0182926829268293 1.7758193597561 0.239165453168384 0.417587817064577 GO:0005539 glycosaminoglycan binding 4/192 242/18639 0.0165289256198347 1.60459710743802 0.2395995671682 0.417587817064577 GO:0030695 GTPase regulator activity 7/192 489/18639 0.0143149284253579 1.38966641104294 0.24060297939045 0.418009606599231 GO:0060589 nucleoside-triphosphatase regulator activity 7/192 490/18639 0.0142857142857143 1.38683035714286 0.242140636763413 0.418678901300921 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/192 27/18639 0.037037037037037 3.59548611111111 0.244038703854818 0.418678901300921 GO:0023026 MHC class II protein complex binding 1/192 27/18639 0.037037037037037 3.59548611111111 0.244038703854818 0.418678901300921 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/192 27/18639 0.037037037037037 3.59548611111111 0.244038703854818 0.418678901300921 GO:0051213 dioxygenase activity 2/192 93/18639 0.021505376344086 2.08770161290323 0.248658880434228 0.419614787952341 GO:0005201 extracellular matrix structural constituent 3/192 168/18639 0.0178571428571429 1.73353794642857 0.250152158580035 0.419614787952341 GO:0036408 histone H3K14 acetyltransferase activity 1/192 28/18639 0.0357142857142857 3.46707589285714 0.25183714404716 0.419614787952341 GO:0045499 chemorepellent activity 1/192 28/18639 0.0357142857142857 3.46707589285714 0.25183714404716 0.419614787952341 GO:0051119 sugar transmembrane transporter activity 1/192 28/18639 0.0357142857142857 3.46707589285714 0.25183714404716 0.419614787952341 GO:0051393 alpha-actinin binding 1/192 28/18639 0.0357142857142857 3.46707589285714 0.25183714404716 0.419614787952341 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/192 28/18639 0.0357142857142857 3.46707589285714 0.25183714404716 0.419614787952341 GO:0097718 disordered domain specific binding 1/192 28/18639 0.0357142857142857 3.46707589285714 0.25183714404716 0.419614787952341 GO:0141052 histone H3 demethylase activity 1/192 28/18639 0.0357142857142857 3.46707589285714 0.25183714404716 0.419614787952341 GO:0042562 hormone binding 2/192 94/18639 0.0212765957446809 2.0654920212766 0.252474489994674 0.419614787952341 GO:0005543 phospholipid binding 7/192 497/18639 0.0140845070422535 1.36729753521127 0.252991793829189 0.419614787952341 GO:0140104 molecular carrier activity 4/192 249/18639 0.0160642570281124 1.55948795180723 0.255245363059211 0.422077422649116 GO:0004857 enzyme inhibitor activity 6/192 416/18639 0.0144230769230769 1.40016526442308 0.258887717333036 0.426424165561575 GO:0010484 histone H3 acetyltransferase activity 1/192 29/18639 0.0344827586206897 3.34752155172414 0.259555550814284 0.426424165561575 GO:0016887 ATP hydrolysis activity 6/192 417/18639 0.0143884892086331 1.39680755395683 0.260618853198873 0.426424165561575 GO:0045296 cadherin binding 5/192 334/18639 0.0149700598802395 1.45326534431138 0.261852896754623 0.426424165561575 GO:0140030 modification-dependent protein binding 3/192 173/18639 0.0173410404624277 1.68343569364162 0.263989048052835 0.426424165561575 GO:0140097 catalytic activity, acting on DNA 5/192 336/18639 0.0148809523809524 1.44461495535714 0.26575851014816 0.426424165561575 GO:0022839 monoatomic ion-gated channel activity 1/192 30/18639 0.0333333333333333 3.2359375 0.267194741262626 0.426424165561575 GO:0032452 histone demethylase activity 1/192 30/18639 0.0333333333333333 3.2359375 0.267194741262626 0.426424165561575 GO:0043995 histone H4K5 acetyltransferase activity 1/192 30/18639 0.0333333333333333 3.2359375 0.267194741262626 0.426424165561575 GO:0043996 histone H4K8 acetyltransferase activity 1/192 30/18639 0.0333333333333333 3.2359375 0.267194741262626 0.426424165561575 GO:0043997 histone H4K12 acetyltransferase activity 1/192 30/18639 0.0333333333333333 3.2359375 0.267194741262626 0.426424165561575 GO:0098918 structural constituent of synapse 1/192 30/18639 0.0333333333333333 3.2359375 0.267194741262626 0.426424165561575 GO:0003735 structural constituent of ribosome 3/192 175/18639 0.0171428571428571 1.66419642857143 0.269551166697634 0.42893794352754 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/192 31/18639 0.032258064516129 3.13155241935484 0.274755524199785 0.429745819902227 GO:0005452 solute:inorganic anion antiporter activity 1/192 31/18639 0.032258064516129 3.13155241935484 0.274755524199785 0.429745819902227 GO:0017147 Wnt-protein binding 1/192 31/18639 0.032258064516129 3.13155241935484 0.274755524199785 0.429745819902227 GO:0047499 calcium-independent phospholipase A2 activity 1/192 31/18639 0.032258064516129 3.13155241935484 0.274755524199785 0.429745819902227 GO:0070325 lipoprotein particle receptor binding 1/192 31/18639 0.032258064516129 3.13155241935484 0.274755524199785 0.429745819902227 GO:0140457 protein demethylase activity 1/192 31/18639 0.032258064516129 3.13155241935484 0.274755524199785 0.429745819902227 GO:0005319 lipid transporter activity 3/192 178/18639 0.0168539325842697 1.6361481741573 0.277919071768853 0.432818565418658 GO:0015106 bicarbonate transmembrane transporter activity 1/192 32/18639 0.03125 3.03369140625 0.28223870021836 0.432818565418658 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/192 32/18639 0.03125 3.03369140625 0.28223870021836 0.432818565418658 GO:0043425 bHLH transcription factor binding 1/192 32/18639 0.03125 3.03369140625 0.28223870021836 0.432818565418658 GO:0047498 calcium-dependent phospholipase A2 activity 1/192 32/18639 0.03125 3.03369140625 0.28223870021836 0.432818565418658 GO:0120015 sterol transfer activity 1/192 32/18639 0.03125 3.03369140625 0.28223870021836 0.432818565418658 GO:0140142 nucleocytoplasmic carrier activity 1/192 32/18639 0.03125 3.03369140625 0.28223870021836 0.432818565418658 GO:0071889 14-3-3 protein binding 1/192 33/18639 0.0303030303030303 2.94176136363636 0.289645061778959 0.442939105617405 GO:0008175 tRNA methyltransferase activity 1/192 34/18639 0.0294117647058824 2.85523897058824 0.296975393292365 0.449144603078536 GO:0030332 cyclin binding 1/192 34/18639 0.0294117647058824 2.85523897058824 0.296975393292365 0.449144603078536 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/192 34/18639 0.0294117647058824 2.85523897058824 0.296975393292365 0.449144603078536 GO:0090482 vitamin transmembrane transporter activity 1/192 34/18639 0.0294117647058824 2.85523897058824 0.296975393292365 0.449144603078536 GO:0000149 SNARE binding 2/192 106/18639 0.0188679245283019 1.83166273584906 0.298262015231552 0.449851226269566 GO:0008234 cysteine-type peptidase activity 3/192 187/18639 0.0160427807486631 1.55740307486631 0.303156296750826 0.452635579103744 GO:0004623 phospholipase A2 activity 1/192 35/18639 0.0285714285714286 2.77366071428571 0.304230471200877 0.452635579103744 GO:0016229 steroid dehydrogenase activity 1/192 35/18639 0.0285714285714286 2.77366071428571 0.304230471200877 0.452635579103744 GO:0034061 DNA polymerase activity 1/192 35/18639 0.0285714285714286 2.77366071428571 0.304230471200877 0.452635579103744 GO:0140566 histone reader activity 1/192 35/18639 0.0285714285714286 2.77366071428571 0.304230471200877 0.452635579103744 GO:0004843 cysteine-type deubiquitinase activity 2/192 108/18639 0.0185185185185185 1.79774305555556 0.30586628104657 0.452768272338727 GO:0140597 protein carrier chaperone 3/192 188/18639 0.0159574468085106 1.54911901595745 0.305969087500305 0.452768272338727 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/192 36/18639 0.0277777777777778 2.69661458333333 0.311411064058834 0.458350332890885 GO:0005484 SNAP receptor activity 1/192 36/18639 0.0277777777777778 2.69661458333333 0.311411064058834 0.458350332890885 GO:0004222 metalloendopeptidase activity 2/192 110/18639 0.0181818181818182 1.76505681818182 0.313455304997963 0.46012556803177 GO:1901681 sulfur compound binding 4/192 275/18639 0.0145454545454545 1.41204545454545 0.314864772567821 0.460962027039289 GO:0022829 wide pore channel activity 1/192 37/18639 0.027027027027027 2.62373310810811 0.318517932612331 0.462609378317909 GO:0023023 MHC protein complex binding 1/192 37/18639 0.027027027027027 2.62373310810811 0.318517932612331 0.462609378317909 GO:0042805 actinin binding 1/192 37/18639 0.027027027027027 2.62373310810811 0.318517932612331 0.462609378317909 GO:0000146 microfilament motor activity 1/192 38/18639 0.0263157894736842 2.5546875 0.325551829878132 0.467874226709672 GO:0005109 frizzled binding 1/192 38/18639 0.0263157894736842 2.5546875 0.325551829878132 0.467874226709672 GO:0005501 retinoid binding 1/192 38/18639 0.0263157894736842 2.5546875 0.325551829878132 0.467874226709672 GO:0019840 isoprenoid binding 1/192 38/18639 0.0263157894736842 2.5546875 0.325551829878132 0.467874226709672 GO:0046982 protein heterodimerization activity 5/192 369/18639 0.013550135501355 1.31542174796748 0.331742979971614 0.470489464357638 GO:0017124 SH3 domain binding 2/192 115/18639 0.0173913043478261 1.6883152173913 0.332344652503426 0.470489464357638 GO:0035401 histone H3Y41 kinase activity 2/192 115/18639 0.0173913043478261 1.6883152173913 0.332344652503426 0.470489464357638 GO:0101005 deubiquitinase activity 2/192 115/18639 0.0173913043478261 1.6883152173913 0.332344652503426 0.470489464357638 GO:0140801 histone H2AXY142 kinase activity 2/192 115/18639 0.0173913043478261 1.6883152173913 0.332344652503426 0.470489464357638 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/192 39/18639 0.0256410256410256 2.48918269230769 0.332513501221791 0.470489464357638 GO:0031267 small GTPase binding 4/192 283/18639 0.0141342756183746 1.37212897526502 0.333502826738294 0.470676225910857 GO:0009055 electron transfer activity 2/192 116/18639 0.0172413793103448 1.67376077586207 0.336105873959547 0.471728158872929 GO:0015144 carbohydrate transmembrane transporter activity 1/192 40/18639 0.025 2.426953125 0.339403684434986 0.471728158872929 GO:0032451 demethylase activity 1/192 40/18639 0.025 2.426953125 0.339403684434986 0.471728158872929 GO:0061791 GTPase motor activity 1/192 40/18639 0.025 2.426953125 0.339403684434986 0.471728158872929 GO:0140662 ATP-dependent protein folding chaperone 1/192 40/18639 0.025 2.426953125 0.339403684434986 0.471728158872929 GO:1990606 membrane scission GTPase motor activity 1/192 40/18639 0.025 2.426953125 0.339403684434986 0.471728158872929 GO:0022853 active monoatomic ion transmembrane transporter activity 2/192 118/18639 0.0169491525423729 1.64539194915254 0.343609416407952 0.476367600020115 GO:0001727 lipid kinase activity 1/192 41/18639 0.024390243902439 2.36775914634146 0.346223109812075 0.478782083845917 GO:0004520 DNA endonuclease activity 1/192 42/18639 0.0238095238095238 2.31138392857143 0.352972500225887 0.482044533890577 GO:0008307 structural constituent of muscle 1/192 42/18639 0.0238095238095238 2.31138392857143 0.352972500225887 0.482044533890577 GO:0019894 kinesin binding 1/192 42/18639 0.0238095238095238 2.31138392857143 0.352972500225887 0.482044533890577 GO:0035198 miRNA binding 1/192 42/18639 0.0238095238095238 2.31138392857143 0.352972500225887 0.482044533890577 GO:0051879 Hsp90 protein binding 1/192 42/18639 0.0238095238095238 2.31138392857143 0.352972500225887 0.482044533890577 GO:0051082 unfolded protein binding 2/192 121/18639 0.0165289256198347 1.60459710743802 0.354813514250645 0.483356375492815 GO:0001046 core promoter sequence-specific DNA binding 1/192 44/18639 0.0227272727272727 2.20632102272727 0.366264030996737 0.495268357185243 GO:0016790 thiolester hydrolase activity 1/192 44/18639 0.0227272727272727 2.20632102272727 0.366264030996737 0.495268357185243 GO:0043014 alpha-tubulin binding 1/192 44/18639 0.0227272727272727 2.20632102272727 0.366264030996737 0.495268357185243 GO:0008094 ATP-dependent activity, acting on DNA 3/192 210/18639 0.0142857142857143 1.38683035714286 0.367862538997556 0.496207700023731 GO:0008009 chemokine activity 1/192 45/18639 0.0222222222222222 2.15729166666667 0.37280758066324 0.4991984433759 GO:0046915 transition metal ion transmembrane transporter activity 1/192 45/18639 0.0222222222222222 2.15729166666667 0.37280758066324 0.4991984433759 GO:0051539 4 iron, 4 sulfur cluster binding 1/192 45/18639 0.0222222222222222 2.15729166666667 0.37280758066324 0.4991984433759 GO:0019783 ubiquitin-like protein peptidase activity 2/192 127/18639 0.015748031496063 1.52878937007874 0.377012930376859 0.503601213569089 GO:0035591 signaling adaptor activity 2/192 129/18639 0.0155038759689922 1.50508720930233 0.384344186313059 0.511463409020446 GO:0001784 phosphotyrosine residue binding 1/192 47/18639 0.0212765957446809 2.0654920212766 0.385693718277714 0.511463409020446 GO:0005504 fatty acid binding 1/192 47/18639 0.0212765957446809 2.0654920212766 0.385693718277714 0.511463409020446 GO:0031072 heat shock protein binding 2/192 131/18639 0.0152671755725191 1.48210877862595 0.391638361704773 0.517376640562183 GO:0032266 phosphatidylinositol-3-phosphate binding 1/192 48/18639 0.0208333333333333 2.0224609375 0.392037672994295 0.517376640562183 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/192 132/18639 0.0151515151515152 1.47088068181818 0.395271053659897 0.520392826041447 GO:0016763 pentosyltransferase activity 1/192 49/18639 0.0204081632653061 1.9811862244898 0.398316451262548 0.523147683596026 GO:0004175 endopeptidase activity 5/192 405/18639 0.0123456790123457 1.19849537037037 0.405219604956767 0.530944064728556 GO:0051020 GTPase binding 4/192 315/18639 0.0126984126984127 1.2327380952381 0.408163649442666 0.533528198914342 GO:0005048 signal sequence binding 1/192 51/18639 0.0196078431372549 1.90349264705882 0.410681136237485 0.535543809487837 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/192 52/18639 0.0192307692307692 1.86688701923077 0.416768354972281 0.540912120283174 GO:0030159 signaling receptor complex adaptor activity 1/192 52/18639 0.0192307692307692 1.86688701923077 0.416768354972281 0.540912120283174 GO:0140767 enzyme-substrate adaptor activity 2/192 139/18639 0.0143884892086331 1.39680755395683 0.420414228933605 0.543591027580229 GO:0004864 protein phosphatase inhibitor activity 1/192 53/18639 0.0188679245283019 1.83166273584906 0.422793021451289 0.543591027580229 GO:0005246 calcium channel regulator activity 1/192 53/18639 0.0188679245283019 1.83166273584906 0.422793021451289 0.543591027580229 GO:0017046 peptide hormone binding 1/192 53/18639 0.0188679245283019 1.83166273584906 0.422793021451289 0.543591027580229 GO:0015485 cholesterol binding 1/192 54/18639 0.0185185185185185 1.79774305555556 0.428755775130476 0.548687460481658 GO:0017069 snRNA binding 1/192 54/18639 0.0185185185185185 1.79774305555556 0.428755775130476 0.548687460481658 GO:0140313 molecular sequestering activity 1/192 55/18639 0.0181818181818182 1.76505681818182 0.434657248962865 0.554946115536308 GO:0019903 protein phosphatase binding 2/192 144/18639 0.0138888888888889 1.34830729166667 0.438046209056782 0.557975333578128 GO:0019212 phosphatase inhibitor activity 1/192 56/18639 0.0178571428571429 1.73353794642857 0.440498069464324 0.558506790152226 GO:0170055 lipid transmembrane transporter activity 1/192 56/18639 0.0178571428571429 1.73353794642857 0.440498069464324 0.558506790152226 GO:0061980 regulatory RNA binding 1/192 58/18639 0.0172413793103448 1.67376077586207 0.452000224742229 0.571769869547198 GO:0015459 potassium channel regulator activity 1/192 59/18639 0.0169491525423729 1.64539194915254 0.457662780947465 0.574958505126221 GO:0036002 pre-mRNA binding 1/192 59/18639 0.0169491525423729 1.64539194915254 0.457662780947465 0.574958505126221 GO:0045309 protein phosphorylated amino acid binding 1/192 59/18639 0.0169491525423729 1.64539194915254 0.457662780947465 0.574958505126221 GO:0001098 basal transcription machinery binding 1/192 60/18639 0.0166666666666667 1.61796875 0.46326712680635 0.578031028674287 GO:0001099 basal RNA polymerase II transcription machinery binding 1/192 60/18639 0.0166666666666667 1.61796875 0.46326712680635 0.578031028674287 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/192 60/18639 0.0166666666666667 1.61796875 0.46326712680635 0.578031028674287 GO:0019905 syntaxin binding 1/192 61/18639 0.0163934426229508 1.59144467213115 0.468813857612808 0.583625414579211 GO:0042277 peptide binding 3/192 249/18639 0.0120481927710843 1.16961596385542 0.474423401243919 0.589272505164959 GO:1901682 sulfur compound transmembrane transporter activity 1/192 63/18639 0.0158730158730159 1.54092261904762 0.479736825024837 0.594527126272315 GO:0004536 DNA nuclease activity 1/192 64/18639 0.015625 1.516845703125 0.485114222182203 0.599837180130697 GO:0038024 cargo receptor activity 1/192 65/18639 0.0153846153846154 1.49350961538462 0.490436325511464 0.602347970259046 GO:0120013 lipid transfer activity 1/192 65/18639 0.0153846153846154 1.49350961538462 0.490436325511464 0.602347970259046 GO:0160215 deacylase activity 1/192 65/18639 0.0153846153846154 1.49350961538462 0.490436325511464 0.602347970259046 GO:0099106 ion channel regulator activity 2/192 160/18639 0.0125 1.2134765625 0.492424688360608 0.603440075691906 GO:0008083 growth factor activity 2/192 162/18639 0.0123456790123457 1.19849537037037 0.498988394148719 0.610121666787631 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/192 67/18639 0.0149253731343284 1.44892723880597 0.500916907410199 0.611118627040442 GO:0003777 microtubule motor activity 1/192 68/18639 0.0147058823529412 1.42761948529412 0.506076500010739 0.614681412623663 GO:0030145 manganese ion binding 1/192 68/18639 0.0147058823529412 1.42761948529412 0.506076500010739 0.614681412623663 GO:0002039 p53 binding 1/192 69/18639 0.0144927536231884 1.40692934782609 0.51118302696125 0.619079400878496 GO:0015399 primary active transmembrane transporter activity 2/192 166/18639 0.0120481927710843 1.16961596385542 0.511952728595332 0.619079400878496 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/192 70/18639 0.0142857142857143 1.38683035714286 0.516237031205916 0.622888198092412 GO:0016247 channel regulator activity 2/192 168/18639 0.0119047619047619 1.15569196428571 0.518352311447315 0.624068901281965 GO:0140299 molecular sensor activity 1/192 71/18639 0.0140845070422535 1.36729753521127 0.521239050162696 0.626171200304859 GO:0141108 transporter regulator activity 2/192 170/18639 0.0117647058823529 1.14209558823529 0.524696213873741 0.627995867527882 GO:0008514 organic anion transmembrane transporter activity 3/192 269/18639 0.0111524163568773 1.08265566914498 0.525892296799791 0.627995867527882 GO:0042379 chemokine receptor binding 1/192 72/18639 0.0138888888888889 1.34830729166667 0.526189615779282 0.627995867527882 GO:0004521 RNA endonuclease activity 1/192 73/18639 0.0136986301369863 1.32983732876712 0.53108925458848 0.632468548306021 GO:0003684 damaged DNA binding 1/192 74/18639 0.0135135135135135 1.31186655405405 0.535938487763047 0.635486457412339 GO:0048029 monosaccharide binding 1/192 74/18639 0.0135135135135135 1.31186655405405 0.535938487763047 0.635486457412339 GO:0019003 GDP binding 1/192 75/18639 0.0133333333333333 1.294375 0.540737831169968 0.637112183867121 GO:0044183 protein folding chaperone 1/192 75/18639 0.0133333333333333 1.294375 0.540737831169968 0.637112183867121 GO:0005126 cytokine receptor binding 3/192 275/18639 0.0109090909090909 1.05903409090909 0.540791034029286 0.637112183867121 GO:0008017 microtubule binding 3/192 276/18639 0.0108695652173913 1.05519701086957 0.543248188496616 0.638636521380391 GO:0051536 iron-sulfur cluster binding 1/192 76/18639 0.0131578947368421 1.27734375 0.54548779542419 0.639899144632223 GO:0005525 GTP binding 4/192 378/18639 0.0105820105820106 1.02728174603175 0.548258349950377 0.641777897916326 GO:0051540 metal cluster binding 1/192 77/18639 0.012987012987013 1.26075487012987 0.550188885941808 0.64266744336607 GO:0033293 monocarboxylic acid binding 1/192 79/18639 0.0126582278481013 1.22883702531646 0.559446441752784 0.650712068903132 GO:0046332 SMAD binding 1/192 79/18639 0.0126582278481013 1.22883702531646 0.559446441752784 0.650712068903132 GO:0015631 tubulin binding 4/192 385/18639 0.0103896103896104 1.0086038961039 0.562797680790486 0.653226060790648 GO:0008237 metallopeptidase activity 2/192 184/18639 0.0108695652173913 1.05519701086957 0.567514437859458 0.657083005322872 GO:0030971 receptor tyrosine kinase binding 1/192 81/18639 0.0123456790123457 1.19849537037037 0.568514439942376 0.657083005322872 GO:0015078 proton transmembrane transporter activity 2/192 185/18639 0.0108108108108108 1.04949324324324 0.570465035687849 0.65795232057275 GO:0001540 amyloid-beta binding 1/192 83/18639 0.0120481927710843 1.16961596385542 0.577396741983708 0.663160693198862 GO:0005254 chloride channel activity 1/192 83/18639 0.0120481927710843 1.16961596385542 0.577396741983708 0.663160693198862 GO:0046943 carboxylic acid transmembrane transporter activity 2/192 188/18639 0.0106382978723404 1.0327460106383 0.579229719005565 0.663877068338319 GO:0004527 exonuclease activity 1/192 84/18639 0.0119047619047619 1.15569196428571 0.581769442217548 0.664418058840419 GO:0005342 organic acid transmembrane transporter activity 2/192 189/18639 0.0105820105820106 1.02728174603175 0.582122197271843 0.664418058840419 GO:0019902 phosphatase binding 2/192 190/18639 0.0105263157894737 1.021875 0.58500011558006 0.66631755903206 GO:0050660 flavin adenine dinucleotide binding 1/192 86/18639 0.0116279069767442 1.12881540697674 0.5903802695451 0.669962859179044 GO:0001664 G protein-coupled receptor binding 3/192 297/18639 0.0101010101010101 0.980587121212121 0.593048349641599 0.669962859179044 GO:0019001 guanyl nucleotide binding 4/192 400/18639 0.01 0.97078125 0.593081875338826 0.669962859179044 GO:0032561 guanyl ribonucleotide binding 4/192 400/18639 0.01 0.97078125 0.593081875338826 0.669962859179044 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/192 91/18639 0.010989010989011 1.06679258241758 0.611143512067696 0.688948230236479 GO:0043178 alcohol binding 1/192 92/18639 0.0108695652173913 1.05519701086957 0.61516876792725 0.692064863918156 GO:0051219 phosphoprotein binding 1/192 93/18639 0.010752688172043 1.04385080645161 0.619152571052174 0.695122211672072 GO:0004896 cytokine receptor activity 1/192 96/18639 0.0104166666666667 1.01123046875 0.630859489171233 0.706820121540831 GO:0043130 ubiquitin binding 1/192 100/18639 0.01 0.97078125 0.645913649201836 0.722213021205311 GO:0005253 monoatomic anion channel activity 1/192 103/18639 0.00970873786407767 0.942506067961165 0.65680202232654 0.732894939547298 GO:0003924 GTPase activity 3/192 331/18639 0.00906344410876133 0.879862160120846 0.665934345963976 0.741578003923373 GO:0004620 phospholipase activity 1/192 109/18639 0.00917431192660551 0.890625 0.677589507871972 0.753029635266625 GO:0000287 magnesium ion binding 2/192 230/18639 0.00869565217391304 0.844157608695652 0.688245296896733 0.76332660201274 GO:1990782 protein tyrosine kinase binding 1/192 117/18639 0.00854700854700855 0.829727564102564 0.703370263277902 0.778528779313645 GO:0032182 ubiquitin-like protein binding 1/192 120/18639 0.00833333333333333 0.808984375 0.712500095536651 0.787047389234651 GO:0004540 RNA nuclease activity 1/192 121/18639 0.00826446280991736 0.802298553719008 0.715480817047368 0.787172281681373 GO:0015108 chloride transmembrane transporter activity 1/192 121/18639 0.00826446280991736 0.802298553719008 0.715480817047368 0.787172281681373 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/192 122/18639 0.00819672131147541 0.795722336065574 0.718430794535591 0.788837012400079 GO:0005267 potassium channel activity 1/192 124/18639 0.00806451612903226 0.78288810483871 0.724239776062689 0.79323627052215 GO:0033218 amide binding 2/192 247/18639 0.00809716599190283 0.786057692307692 0.72532715446652 0.79323627052215 GO:0004519 endonuclease activity 1/192 127/18639 0.0078740157480315 0.76439468503937 0.732730450706813 0.799739597292326 GO:0016298 lipase activity 1/192 130/18639 0.00769230769230769 0.746754807692308 0.74096101674282 0.803928059667605 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/192 130/18639 0.00769230769230769 0.746754807692308 0.74096101674282 0.803928059667605 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/192 130/18639 0.00769230769230769 0.746754807692308 0.74096101674282 0.803928059667605 GO:0005179 hormone activity 1/192 132/18639 0.00757575757575758 0.735440340909091 0.746307480962773 0.808131769326553 GO:0015297 antiporter activity 1/192 135/18639 0.00740740740740741 0.719097222222222 0.754122031154852 0.811354762646833 GO:0003730 mRNA 3'-UTR binding 2/192 262/18639 0.00763358778625954 0.741054389312977 0.754900787852056 0.811354762646833 GO:0002020 protease binding 1/192 136/18639 0.00735294117647059 0.713809742647059 0.756673294126008 0.811354762646833 GO:0016779 nucleotidyltransferase activity 1/192 136/18639 0.00735294117647059 0.713809742647059 0.756673294126008 0.811354762646833 GO:0099094 ligand-gated monoatomic cation channel activity 1/192 136/18639 0.00735294117647059 0.713809742647059 0.756673294126008 0.811354762646833 GO:0070851 growth factor receptor binding 1/192 139/18639 0.00719424460431655 0.698403776978417 0.764170147288605 0.814956758408431 GO:0140101 catalytic activity, acting on a tRNA 1/192 139/18639 0.00719424460431655 0.698403776978417 0.764170147288605 0.814956758408431 GO:0140098 catalytic activity, acting on RNA 3/192 387/18639 0.00775193798449612 0.752543604651163 0.764485848051625 0.814956758408431 GO:0016791 phosphatase activity 2/192 273/18639 0.00732600732600733 0.711195054945055 0.774815386527777 0.8243675333406 GO:0008194 UDP-glycosyltransferase activity 1/192 145/18639 0.00689655172413793 0.669504310344828 0.778481430470838 0.826665967753366 GO:0030246 carbohydrate binding 2/192 280/18639 0.00714285714285714 0.693415178571429 0.786744117325844 0.833061366739606 GO:0008509 monoatomic anion transmembrane transporter activity 1/192 149/18639 0.00671140939597315 0.651531040268456 0.787538887682797 0.833061366739606 GO:0005506 iron ion binding 1/192 154/18639 0.00649350649350649 0.630377435064935 0.798344279537565 0.84286732589639 GO:0140375 immune receptor activity 1/192 156/18639 0.00641025641025641 0.622295673076923 0.802511751244412 0.845640981637586 GO:0015079 potassium ion transmembrane transporter activity 1/192 160/18639 0.00625 0.60673828125 0.810591387135545 0.852518527849453 GO:0015103 inorganic anion transmembrane transporter activity 1/192 165/18639 0.00606060606060606 0.588352272727273 0.820229985805123 0.859855850586719 GO:0031625 ubiquitin protein ligase binding 2/192 302/18639 0.00662251655629139 0.642901490066225 0.820700301835047 0.859855850586719 GO:0004252 serine-type endopeptidase activity 1/192 176/18639 0.00568181818181818 0.551580255681818 0.839751457871392 0.878140095945513 GO:0044389 ubiquitin-like protein ligase binding 2/192 322/18639 0.0062111801242236 0.602969720496894 0.847297119795356 0.883309834724912 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/192 181/18639 0.00552486187845304 0.536343232044199 0.847913083606609 0.883309834724912 GO:0022804 active transmembrane transporter activity 3/192 457/18639 0.00656455142231947 0.637274343544858 0.853186139848973 0.887119679502057 GO:0015276 ligand-gated monoatomic ion channel activity 1/192 186/18639 0.00537634408602151 0.521925403225806 0.855661084043623 0.887605104944078 GO:0031406 carboxylic acid binding 1/192 187/18639 0.0053475935828877 0.51913435828877 0.857162903361003 0.887605104944078 GO:0022834 ligand-gated channel activity 1/192 188/18639 0.00531914893617021 0.516373005319149 0.858649177074134 0.887605104944078 GO:0043177 organic acid binding 1/192 189/18639 0.00529100529100529 0.513640873015873 0.860120065264571 0.887605104944078 GO:0008236 serine-type peptidase activity 1/192 194/18639 0.00515463917525773 0.500402706185567 0.867249212371733 0.89328295983505 GO:0017171 serine hydrolase activity 1/192 198/18639 0.00505050505050505 0.490293560606061 0.872691325263215 0.897205126534653 GO:0061630 ubiquitin protein ligase activity 2/192 353/18639 0.0056657223796034 0.550017705382436 0.881522600493932 0.904590481628352 GO:0004518 nuclease activity 1/192 209/18639 0.00478468899521531 0.464488636363636 0.886539419552321 0.908041308459373 GO:0016755 aminoacyltransferase activity 3/192 496/18639 0.00604838709677419 0.587166078629032 0.88878484332506 0.90864595714238 GO:0042578 phosphoric ester hydrolase activity 2/192 363/18639 0.00550964187327824 0.534865702479339 0.890962232285219 0.909178932201831 GO:0061659 ubiquitin-like protein ligase activity 2/192 372/18639 0.00537634408602151 0.521925403225806 0.89885912678604 0.915535548433277 GO:0005085 guanyl-nucleotide exchange factor activity 1/192 230/18639 0.00434782608695652 0.422078804347826 0.908949514554245 0.924098673130149 GO:0005125 cytokine activity 1/192 234/18639 0.00427350427350427 0.414863782051282 0.912689310883242 0.926185640803882 GO:0016757 glycosyltransferase activity 1/192 267/18639 0.00374531835205993 0.363588483146067 0.938249157039967 0.950366766079229 GO:0005216 monoatomic ion channel activity 2/192 448/18639 0.00446428571428571 0.433384486607143 0.947209746059249 0.95508139563761 GO:0004842 ubiquitin-protein transferase activity 2/192 449/18639 0.0044543429844098 0.432419265033408 0.947668109149259 0.95508139563761 GO:0046873 metal ion transmembrane transporter activity 2/192 450/18639 0.00444444444444444 0.431458333333333 0.94812269694444 0.95508139563761 GO:0015291 secondary active transmembrane transporter activity 1/192 287/18639 0.00348432055749129 0.338251306620209 0.949956893001863 0.955176436370005 GO:0019787 ubiquitin-like protein transferase activity 2/192 479/18639 0.00417536534446764 0.405336638830898 0.95978635672752 0.963295630426706 GO:0022836 gated channel activity 1/192 318/18639 0.00314465408805031 0.305277122641509 0.96388949636116 0.965648418799776 GO:0005261 monoatomic cation channel activity 1/192 341/18639 0.00293255131964809 0.284686583577713 0.971664069076284 0.971664069076284