category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	6/51	78/9376	14.1417797888386	FOS/C3/SERPING1/JUN/MAPK10/C2	8.61892342160389
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	9/51	300/9376	5.51529411764706	FOS/JUND/JUN/HSPA1B/IGF2/RPS6KA2/HGF/MAPK10/INSR	5.87821862446233
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	7/51	203/9376	6.3394185260311	COL6A2/COL6A1/TNXB/JUN/HGF/MAPK10/TNC	5.68764644819247
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	5/51	88/9376	10.445632798574	C3/SERPING1/CFD/C2/PLAT	6.58351147657461
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	6/51	142/9376	7.76801988400994	FOS/JUND/FOSB/JUN/JUNB/MAPK10	6.00976055729388
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	5/51	93/9376	9.88403963736032	JUN/MMP14/EGR1/MAPK10/MMP2	6.36728211558144
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	5/51	94/9376	9.77889027951606	FOS/JUND/FOSB/JUN/MAPK10	6.32599831526423
NA	NA	hsa04518	Integrin signaling	6/51	154/9376	7.16271963330787	C3/COL6A2/COL6A1/TNXB/HGF/TNC	5.70251607080597
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	7/51	227/9376	5.66917163341107	MT-ND3/FOS/JUN/MT-ND1/HGF/MAPK10/MT-ATP6	5.26638080546055
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	7/51	233/9376	5.52318438104856	COL6A2/VIM/COL6A1/SGCE/PLEC/ANK2/SUN1	5.17040065733988
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	5/51	119/9376	7.72450156533202	FOS/JUN/MMP14/JUNB/MAPK10	5.45939796910865
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	6/51	205/9376	5.38077474892396	MT-ND3/MT-ND1/MAPK10/MMP2/INSR/MT-ATP6	4.68992408555102
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	5/51	142/9376	6.47334990334162	FOS/JUN/MAPK10/MMP2/PLAT	4.86013973497398
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/51	89/9376	8.26261291033267	COL6A2/COL6A1/TNXB/TNC	5.09092247827489
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	6/51	238/9376	4.63470093919921	FOS/C3/JUN/CFD/MAPK10/C2	4.20027660027039
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	4/51	99/9376	7.4280055456526	FOS/JUN/MAPK10/MMP2	4.7548450388697
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/51	101/9376	7.28091632692681	JUN/EGR1/MAPK10/MMP2	4.69324300590327
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	4/51	103/9376	7.13953931086998	FOS/C3/JUN/MAPK10	4.63330161972448
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/51	109/9376	6.74653714696888	FOS/JUN/MAPK10/CCL4	4.46268457649376
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	7/51	362/9376	3.55497779222186	COL6A2/COL6A1/TNXB/IGF2/HGF/TNC/INSR	3.66630797938555
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	4/51	115/9376	6.39454390451833	FOS/JUND/MMP14/EGR1	4.30448318983275
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	6/51	275/9376	4.01112299465241	MT-ND3/EGR1/HSPA1B/MT-ND1/MAPK10/MT-ATP6	3.74797418685981
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/51	196/9376	4.68987595038015	FOS/C3/ZFP36/JUN/MAPK10	3.8606885447489
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	4/51	122/9376	6.02764384442302	IGFBP3/FOS/JUNB/MAPK10	4.13357649205375
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	4/51	130/9376	5.65671191553545	FOS/JUN/MAPK10/MMP2	3.95385200175287
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/51	69/9376	7.99317988064791	FOS/FOSB/JUN	4.31162214510351
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/51	136/9376	5.40715109573241	FOS/JUN/HSPA1B/MAPK10	3.82857989845464
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/51	138/9376	5.32878658709861	FOS/JUN/RPS6KA2/MAPK10	3.7884629601477
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/51	139/9376	5.29044999294682	FOS/JUN/HSPA1B/MMP2	3.76869575752886
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	5/51	224/9376	4.10364145658263	FOS/ZFP36/JUN/EGR1/MAPK10	3.47683318152327
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/51	78/9376	7.07088989441931	FOS/C3/JUN	3.98154100447098
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/51	157/9376	4.68390158611215	FOS/JUN/MAPK10/INSR	3.44240722363203
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/51	87/9376	6.3394185260311	FOS/JUN/MAPK10	3.70011664173221
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/51	93/9376	5.93042378241619	FOS/JUN/MAPK10	3.53368517627909
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/51	95/9376	5.80557275541796	FOS/CXCL12/JUN	3.48141566455605
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/51	99/9376	5.57100415923945	C3/CFD/C2	3.38120686033196
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	3/51	99/9376	5.57100415923945	FOS/JUN/MAPK10	3.38120686033196
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/51	109/9376	5.05990286022666	FOS/JUN/MAPK10	3.15286674618525
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	3/51	109/9376	5.05990286022666	RPS6KA2/MAPK10/INSR	3.15286674618525
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/51	204/9376	3.60476739715494	IGF2/HGF/MMP2/ANK2	2.78162329056339
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	4/51	205/9376	3.58718316594931	C3/JUN/HDAC7/GSN	2.76975953778454
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	5/51	308/9376	2.98446651387828	MT-ND3/TGM2/MT-ND1/MAPK10/MT-ATP6	2.61884432848665
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	2/51	47/9376	7.82311222361285	MAPK10/INSR	3.46784919216579
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/51	120/9376	4.59607843137255	JUN/RPS6KA2/MAPK10	2.93193549540002
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/51	122/9376	4.52073288331726	FOS/JUN/MAPK10	2.89463994101814
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/51	49/9376	7.50380152060824	FOSB/JUN	3.37551962179052
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	4/51	216/9376	3.40450254175744	FOS/JUN/HSPA1B/MAPK10	2.64393445965506
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/51	56/9376	6.56582633053221	C3/HSPA1B	3.08931372824949
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/51	137/9376	4.02576212966939	FOS/JUN/MAPK10	2.63832862228196
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	4/51	235/9376	3.12924488944514	MT-ND3/MT-ND1/RPS6KA2/MT-ATP6	2.44460669156169
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/51	138/9376	3.99658994032396	MT-ND3/MT-ND1/MT-ATP6	2.62255247914117
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/51	238/9376	3.08980062613281	IGF2/HGF/MAPK10/INSR	2.41498291496574
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/51	144/9376	3.83006535947712	C3/MAPK10/C2	2.53090660778915
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/51	62/9376	5.93042378241619	HSPA1B/INSR	2.88043635423791
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	3/51	149/9376	3.70153967627319	MT-ND3/MT-ND1/MAPK10	2.45821876808693
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/51	158/9376	3.49069247952346	RPS6KA2/NPRL3/INSR	2.33494474128394
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/51	70/9376	5.25266106442577	JUN/HGF	2.64103753108422
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/51	71/9376	5.17867992267329	FOS/MAPK10	2.61370397339994
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/51	71/9376	5.17867992267329	JUN/MAPK10	2.61370397339994
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/51	268/9376	2.74392742171495	MT-ND3/MT-ND1/MAPK10/MT-ATP6	2.14205490615102
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/51	163/9376	3.38361602309636	FOS/JUN/MAPK10	2.27026141911384
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	5/51	388/9376	2.369112593491	MT-ND3/MT-ND1/MAPK10/INSR/MT-ATP6	2.0369004408539
Metabolism	Glycan biosynthesis and metabolism	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/51	14/9376	13.1316526610644	B3GNT2	3.35927821131726
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/51	83/9376	4.42995511457595	GSDME/CCL4	2.32111052242077
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	3/51	184/9376	2.99744245524297	CXCL12/SLIT3/ROBO3	2.02359913993848
NA	NA	hsa04517	IgSF CAM signaling	4/51	299/9376	2.45943996327628	MAPK10/ANK2/SLIT3/ROBO3	1.89669267360127
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/51	86/9376	4.27542179662563	JUN/MAPK10	2.25660169173524
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/51	90/9376	4.08540305010893	FOS/JUN	2.17502936926057
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/51	91/9376	4.04050851109675	FOS/JUN	2.15537217294499
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/51	200/9376	2.75764705882353	FOS/JUN/MAPK10	1.85808797691801
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/51	205/9376	2.69038737446198	VIM/JUN/MAPK10	1.8096772639013
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/51	100/9376	3.67686274509804	CXCL12/CCL4	1.99017854266899
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	4/51	333/9376	2.20832597303186	COL6A2/COL6A1/TNXB/TNC	1.66033708412753
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/51	103/9376	3.56976965543499	COL6A2/COL6A1	1.93931780610402
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/51	212/9376	2.6015538290788	HGF/EVL/INSR	1.74426809215793
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/51	214/9376	2.57724024189115	FOS/JUN/MAPK10	1.72606003928979
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/51	105/9376	3.50177404295051	CXCL12/CCL4	1.90645143802245
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/51	105/9376	3.50177404295051	JUN/MAPK10	1.90645143802245
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/51	105/9376	3.50177404295051	JUN/MAPK10	1.90645143802245
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/51	217/9376	2.54161019246408	FOS/JUN/RPS6KA2	1.69913042468789
NA	NA	hsa04081	Hormone signaling	3/51	219/9376	2.51839914047811	IGF2/AVPR1A/INSR	1.68142579449365
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/51	110/9376	3.34260249554367	RPS6KA2/MAPK10	1.82765871746828
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/51	112/9376	3.28291316526611	HSPA1B/MAPK10	1.79740289468934
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/51	226/9376	2.44039562727746	FOS/JUN/MAPK10	1.62095803980985
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/51	116/9376	3.16970926301555	CXCL12/MMP2	1.73888695873659
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/51	28/9376	6.56582633053221	B3GNT2	2.18120066196397
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/51	248/9376	2.22390891840607	FOS/JUN/MAPK10	1.44455283235074
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	3/51	253/9376	2.17995814926761	C3/JUN/MAPK10	1.40703316156644
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/51	32/9376	5.74509803921569	MAPK10	1.98838313164976
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/51	133/9376	2.76455845496093	MAPK10/INSR	1.5156596881843
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/51	133/9376	2.76455845496093	FOS/MAPK10	1.5156596881843
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/51	138/9376	2.6643932935493	MAPK10/INSR	1.45664199813465
NA	NA	hsa04519	Cadherin signaling	4/51	404/9376	1.8202290817317	VIM/CDH11/MAPK10/EVL	1.24631413195244
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/51	140/9376	2.62633053221289	EGR1/PLAT	1.43376236749821
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/51	143/9376	2.57123268887975	C3/C2	1.40017852620789
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/51	38/9376	4.83797729618163	INSR	1.75312777682701
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/51	148/9376	2.48436671966084	FOS/JUN	1.34606049790794
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	2/51	149/9376	2.46769311751546	AVPR1A/INSR	1.33550167667561
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/51	41/9376	4.48397895743663	MMP2	1.65331877087326
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/51	154/9376	2.38757321110262	FOS/JUN	1.2839556245536
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/51	170/9376	2.16286043829296	JUN/MAPK10	1.13152167368107
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/51	170/9376	2.16286043829296	IGF2/HGF	1.13152167368107
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/51	50/9376	3.67686274509804	CXCL12	1.40349123945021
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/51	50/9376	3.67686274509804	HGF	1.40349123945021
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/51	174/9376	2.11313950867703	HSPA1B/MAPK10	1.09604759418772
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/51	52/9376	3.53544494720965	INSR	1.35581686076094
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/51	178/9376	2.06565322758317	JUN/MAPK10	1.06151346927522
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	3/51	323/9376	1.70752139865234	VIM/TNXB/TNC	0.956953612894988
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/51	181/9376	2.03141588126964	C3/MAPK10	1.03619988760977
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	4/51	480/9376	1.53202614379085	MT-ND3/MT-ND1/MAPK10/MT-ATP6	0.884916945604477
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/51	187/9376	1.96623676208451	JUN/MAPK10	0.986998608603371
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/51	59/9376	3.11598537720173	INSR	1.20572128079155
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/51	191/9376	1.92505902884714	FOSB/HDAC7	0.955196792951992
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	2/51	193/9376	1.90511023062075	CXCL12/CCL4	0.939580818693962
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/51	195/9376	1.88557063851181	C3/HDAC7	0.924148636053861
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/51	201/9376	1.82928494780997	IGFBP3/PLAT	0.878911366306338
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/51	66/9376	2.78550207961973	JUN	1.07647461681609
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/51	67/9376	2.74392742171495	RPS6KA2	1.05940153736648
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/51	69/9376	2.6643932935493	MAPK10	1.02617623243006
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/51	70/9376	2.62633053221289	MAPK10	1.01000289194276
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/51	70/9376	2.62633053221289	SGCE	1.01000289194276
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	3/51	368/9376	1.49872122762148	MT-ND3/MT-ND1/MT-ATP6	0.721795018710832
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/51	72/9376	2.55337690631808	MAPK10	0.97848584554604
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/51	73/9376	2.51839914047811	HGF	0.963123932786538
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/51	73/9376	2.51839914047811	HGF	0.963123932786538
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/51	75/9376	2.45124183006536	IGFBP3	0.933150951771406
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/51	76/9376	2.41898864809082	FABP5	0.918524085805873
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/51	76/9376	2.41898864809082	SLC26A7	0.918524085805873
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/51	77/9376	2.38757321110262	MAPK10	0.904127026174409
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/51	227/9376	1.61976332383174	CXCL12/CCL4	0.699033989070011
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/51	80/9376	2.29803921568627	HGF	0.862245735925945
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/51	232/9376	1.58485463150778	CXCL12/GSN	0.667068024067711
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/51	82/9376	2.24198947871832	HSPA1B	0.835352573589998
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/51	86/9376	2.13771089831281	SGCE	0.783825869536325
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/51	90/9376	2.04270152505447	INSR	0.735043818760138
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/51	250/9376	1.47074509803922	HSPA1B/RAB31	0.557907095002965
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/51	93/9376	1.97680792747206	INSR	0.700088236976738
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/51	93/9376	1.97680792747206	LYZ	0.700088236976738
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/51	254/9376	1.44758375791261	HGF/AVPR1A	0.534801293090201
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/51	97/9376	1.8952900747928	FOS	0.655458735328431
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/51	98/9376	1.87595038015206	GSN	0.644631710261329
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/51	99/9376	1.85700138641315	MAPK10	0.633930503256485
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/51	99/9376	1.85700138641315	SGCE	0.633930503256485
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/51	105/9376	1.75088702147526	SGCE	0.572205809680396
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/51	106/9376	1.73436921938587	PLAT	0.562307449304359
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/51	110/9376	1.67130124777184	INSR	0.523737842792995
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/51	110/9376	1.67130124777184	ID4	0.523737842792995
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/51	115/9376	1.59863597612958	FOS	0.477671243702481
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/51	298/9376	1.23384655875773	CXCL12/CCL4	0.303382364726905
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/51	122/9376	1.50691096110575	INSR	0.416766838946919
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/51	125/9376	1.47074509803922	MAPK10	0.391825573885612
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/51	134/9376	1.37196371085748	AVPR1A	0.320712801041836
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/51	138/9376	1.33219664677465	RPS6KA2	0.29073151712812
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/51	144/9376	1.27668845315904	ID4	0.24744044587315
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/51	144/9376	1.27668845315904	MAPK10	0.24744044587315
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/51	150/9376	1.22562091503268	HGF	0.205998741247037
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/51	155/9376	1.18608475648324	C3	0.172756319311916
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/51	157/9376	1.17097539652804	IGFBP3	0.159767281050691
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/51	166/9376	1.10748877864399	INSR	0.103331721106191
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/51	168/9376	1.09430438842204	MAPK10	0.0912116253046077
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/51	370/9376	0.993746687864335	C3/AVPR1A	-0.00907593347390288
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/51	169/9376	1.08782921452605	MAPK10	0.0852058837982095
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/51	180/9376	1.02135076252723	C3	0.0213892948588904
NA	NA	hsa04382	Cornified envelope formation	1/51	217/9376	0.847203397488028	PLEC	-0.168409210957577
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/51	243/9376	0.756556120390543	HSPA1B	-0.284342367060358