ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 88/1988 175/18639 0.502857142857143 4.7146651336591 1.32315487193807e-39 1.61160263402056e-36 GO:0019843 rRNA binding 29/1988 65/18639 0.446153846153846 4.1830289428881 2.85914840358099e-12 1.74122137778082e-09 GO:0051082 unfolded protein binding 39/1988 121/18639 0.322314049586777 3.02193740958146 1.08366549835013e-10 3.40495719077584e-08 GO:0044389 ubiquitin-like protein ligase binding 74/1988 322/18639 0.229813664596273 2.15467650624242 1.11821254212671e-10 3.40495719077584e-08 GO:0009055 electron transfer activity 36/1988 116/18639 0.310344827586207 2.90971692222299 1.79900712329573e-09 4.38238135234839e-07 GO:0043021 ribonucleoprotein complex binding 46/1988 177/18639 0.259887005649718 2.43663676977117 6.76192250880893e-09 1.37267026928821e-06 GO:0031625 ubiquitin protein ligase binding 66/1988 302/18639 0.218543046357616 2.04900595626741 9.73021085193282e-09 1.69305668823631e-06 GO:0030515 snoRNA binding 16/1988 32/18639 0.5 4.68787726358149 2.99147222264828e-08 4.554516458982e-06 GO:0044183 protein folding chaperone 25/1988 75/18639 0.333333333333333 3.12525150905433 1.11840386891913e-07 1.51357323593722e-05 GO:0016860 intramolecular oxidoreductase activity 20/1988 53/18639 0.377358490566038 3.53802057628792 2.06113001985491e-07 2.51045636418328e-05 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 23/1988 68/18639 0.338235294117647 3.17121109006983 2.64553759559206e-07 2.92933162857375e-05 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 20/1988 54/18639 0.37037037037037 3.47250167672703 2.94671870403392e-07 2.99091948459443e-05 GO:0045296 cadherin binding 66/1988 334/18639 0.197604790419162 1.85269400836155 5.25673727610611e-07 4.92515846330557e-05 GO:0051540 metal cluster binding 24/1988 77/18639 0.311688311688312 2.92231309937547 8.10339077923739e-07 7.04994997793653e-05 GO:0015036 disulfide oxidoreductase activity 16/1988 40/18639 0.4 3.75030181086519 1.359410327484e-06 0.00010348511117972 GO:0140662 ATP-dependent protein folding chaperone 16/1988 40/18639 0.4 3.75030181086519 1.359410327484e-06 0.00010348511117972 GO:0051537 2 iron, 2 sulfur cluster binding 13/1988 28/18639 0.464285714285714 4.35302888761138 1.77621426031975e-06 0.000127260527592321 GO:0051536 iron-sulfur cluster binding 23/1988 76/18639 0.302631578947368 2.83739939637827 2.41819379252888e-06 0.000163631113294454 GO:0031386 protein tag activity 9/1988 15/18639 0.6 5.62545271629779 4.82148706145083e-06 0.000286225403905646 GO:0141047 molecular tag activity 9/1988 15/18639 0.6 5.62545271629779 4.82148706145083e-06 0.000286225403905646 GO:0016853 isomerase activity 40/1988 180/18639 0.222222222222222 2.08350100603622 4.9349207569939e-06 0.000286225403905646 GO:0015035 protein-disulfide reductase activity 13/1988 34/18639 0.382352941176471 3.58484731920937 2.37928495544318e-05 0.00131725867078627 GO:0033218 amide binding 48/1988 247/18639 0.194331983805668 1.82200897693855 2.8113332411674e-05 0.00147301568032036 GO:1901681 sulfur compound binding 52/1988 275/18639 0.189090909090909 1.77286994695445 2.90249395137016e-05 0.00147301568032036 GO:0043022 ribosome binding 27/1988 112/18639 0.241071428571429 2.26022653779822 3.66034278422403e-05 0.00178331900447395 GO:0008137 NADH dehydrogenase (ubiquinone) activity 14/1988 41/18639 0.341463414634146 3.20147715561663 5.10532357716875e-05 0.00239164773730444 GO:0003756 protein disulfide isomerase activity 9/1988 19/18639 0.473684210526316 4.44114688128773 5.97397757237411e-05 0.00251770684024404 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 9/1988 19/18639 0.473684210526316 4.44114688128773 5.97397757237411e-05 0.00251770684024404 GO:0016504 peptidase activator activity 17/1988 57/18639 0.298245614035088 2.79627766599598 5.99454009581914e-05 0.00251770684024404 GO:0005178 integrin binding 34/1988 161/18639 0.211180124223602 1.97997300573628 7.35060823841416e-05 0.00298434694479615 GO:0140098 catalytic activity, acting on RNA 66/1988 387/18639 0.170542635658915 1.59896588835338 7.95634654069627e-05 0.00312607422147357 GO:0001618 virus receptor activity 21/1988 81/18639 0.259259259259259 2.43075117370892 8.53642628012283e-05 0.00324917725287175 GO:0022853 active monoatomic ion transmembrane transporter activity 27/1988 118/18639 0.228813559322034 2.14529976468983 9.60389975629737e-05 0.00354471209186976 GO:0140272 exogenous protein binding 21/1988 82/18639 0.25609756097561 2.40110786671247 0.000103361401726377 0.00370277021478609 GO:0003954 NADH dehydrogenase activity 14/1988 44/18639 0.318181818181818 2.98319462227913 0.00012244386758379 0.0042610465919159 GO:0000287 magnesium ion binding 43/1988 230/18639 0.18695652173913 1.7528584550783 0.000177997267310819 0.00602224087734937 GO:0001094 TFIID-class transcription factor complex binding 6/1988 10/18639 0.6 5.62545271629779 0.000209755910211303 0.00684300003344669 GO:0016209 antioxidant activity 21/1988 86/18639 0.244186046511628 2.28942843105142 0.000213492611880931 0.00684300003344669 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 16/1988 58/18639 0.275862068965517 2.58641504197599 0.000268458374536666 0.00823483418332875 GO:0008191 metalloendopeptidase inhibitor activity 7/1988 14/18639 0.5 4.68787726358149 0.000270437904214409 0.00823483418332875 GO:0016829 lyase activity 38/1988 200/18639 0.19 1.78139336016097 0.00029457786285785 0.00875111797465515 GO:0016879 ligase activity, forming carbon-nitrogen bonds 14/1988 48/18639 0.291666666666667 2.73459507042254 0.000341252342062157 0.00989631791980255 GO:0004602 glutathione peroxidase activity 9/1988 23/18639 0.391304347826087 3.66877351062899 0.000355470472308826 0.0100689077970268 GO:0015485 cholesterol binding 15/1988 54/18639 0.277777777777778 2.60437625754527 0.000381046464086051 0.0105480589376548 GO:0070990 snRNP binding 6/1988 11/18639 0.545454545454545 5.11404792390708 0.000419743075107008 0.011361045899563 GO:0048027 mRNA 5'-UTR binding 9/1988 24/18639 0.375 3.51590794768612 0.000515243097715347 0.0135396407912808 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 12/1988 39/18639 0.307692307692308 2.88484754681938 0.000522465613456648 0.0135396407912808 GO:0048029 monosaccharide binding 18/1988 74/18639 0.243243243243243 2.28058893903964 0.000618206696550114 0.0153879978005897 GO:0032934 sterol binding 17/1988 68/18639 0.25 2.34393863179074 0.000619057382782346 0.0153879978005897 GO:0140101 catalytic activity, acting on a tRNA 28/1988 139/18639 0.201438848920863 1.88864119971628 0.000679927375870372 0.0165630308762023 GO:0140297 DNA-binding transcription factor binding 75/1988 488/18639 0.153688524590164 1.44094588019923 0.000738161651737176 0.017629037094429 GO:0051787 misfolded protein binding 7/1988 17/18639 0.411764705882353 3.8606048053024 0.00114807998505127 0.0268915658037009 GO:0005518 collagen binding 17/1988 72/18639 0.236111111111111 2.21371981891348 0.00123729461604397 0.0284344309875764 GO:0061133 endopeptidase activator activity 8/1988 22/18639 0.363636363636364 3.40936528260472 0.00133515663652746 0.0298902739691497 GO:0015399 primary active transmembrane transporter activity 31/1988 166/18639 0.186746987951807 1.75089391772321 0.00135925057151344 0.0298902739691497 GO:0023026 MHC class II protein complex binding 9/1988 27/18639 0.333333333333333 3.12525150905433 0.00137426546984596 0.0298902739691497 GO:0043178 alcohol binding 20/1988 92/18639 0.217391304347826 2.038207505905 0.00144797984229275 0.0309410429458346 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 15/1988 61/18639 0.245901639344262 2.30551340831877 0.00151827993737159 0.0318838786848034 GO:0048306 calcium-dependent protein binding 18/1988 80/18639 0.225 2.10954476861167 0.00162744855316185 0.0335971582669684 GO:0061134 peptidase regulator activity 39/1988 226/18639 0.172566371681416 1.61793994052812 0.0016994969838753 0.0340819899077774 GO:0003746 translation elongation factor activity 7/1988 18/18639 0.388888888888889 3.64612676056338 0.00170689768832054 0.0340819899077774 GO:0042277 peptide binding 42/1988 249/18639 0.168674698795181 1.58145257084677 0.00181858381586702 0.0357263723826779 GO:0019003 GDP binding 17/1988 75/18639 0.226666666666667 2.12517102615694 0.00198986606562472 0.0384707439354113 GO:0044548 S100 protein binding 6/1988 14/18639 0.428571428571429 4.01818051164128 0.00205598042094636 0.0390749594973238 GO:0015078 proton transmembrane transporter activity 33/1988 185/18639 0.178378378378378 1.67243188862907 0.00214038674055406 0.0390749594973238 GO:0004601 peroxidase activity 14/1988 57/18639 0.245614035087719 2.30281690140845 0.00217851096074258 0.0390749594973238 GO:0016783 sulfurtransferase activity 5/1988 10/18639 0.5 4.68787726358149 0.00218244925102929 0.0390749594973238 GO:0047429 nucleoside triphosphate diphosphatase activity 5/1988 10/18639 0.5 4.68787726358149 0.00218244925102929 0.0390749594973238 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 24/1988 122/18639 0.19672131147541 1.84441072665501 0.00221360607989765 0.0390749594973238 GO:0008238 exopeptidase activity 21/1988 102/18639 0.205882352941176 1.9303024026512 0.00228352167439281 0.039733277134435 GO:0001091 RNA polymerase II general transcription initiation factor binding 8/1988 24/18639 0.333333333333333 3.12525150905433 0.00252886233730842 0.043382455307629 GO:0005525 GTP binding 58/1988 378/18639 0.153439153439153 1.4386078375012 0.00287395983181864 0.0481793657031447 GO:0051117 ATPase binding 18/1988 84/18639 0.214285714285714 2.00909025582064 0.00288759745183051 0.0481793657031447 GO:0016874 ligase activity 30/1988 167/18639 0.179640718562874 1.68426728032868 0.00297256514843118 0.0489268155512052 GO:0042287 MHC protein binding 11/1988 41/18639 0.268292682926829 2.51544633655592 0.00301921433307457 0.049032040769131 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 14/1988 59/18639 0.23728813559322 2.2247553115302 0.00307454676449553 0.0492736573573099 GO:0019207 kinase regulator activity 46/1988 287/18639 0.160278745644599 1.50273417508536 0.00322431121717355 0.0508798796943271 GO:0005201 extracellular matrix structural constituent 30/1988 168/18639 0.178571428571429 1.67424187985053 0.00325831741884853 0.0508798796943271 GO:0005200 structural constituent of cytoskeleton 22/1988 112/18639 0.196428571428571 1.84166606783558 0.00336629501663347 0.051394379914128 GO:0120020 cholesterol transfer activity 8/1988 25/18639 0.32 3.00024144869215 0.00337565713721694 0.051394379914128 GO:0042288 MHC class I protein binding 7/1988 20/18639 0.35 3.28151408450704 0.00343424360698097 0.0516408483123805 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 5/1988 11/18639 0.454545454545455 4.2617066032559 0.00365137106429785 0.0535827705580094 GO:0034713 type I transforming growth factor beta receptor binding 5/1988 11/18639 0.454545454545455 4.2617066032559 0.00365137106429785 0.0535827705580094 GO:0023023 MHC protein complex binding 10/1988 37/18639 0.27027027027027 2.53398771004405 0.00435058040576858 0.0623412580497191 GO:0043394 proteoglycan binding 10/1988 37/18639 0.27027027027027 2.53398771004405 0.00435058040576858 0.0623412580497191 GO:0048156 tau protein binding 11/1988 43/18639 0.255813953488372 2.39844883253006 0.00450543454859353 0.0638095265138014 GO:0002020 protease binding 25/1988 136/18639 0.183823529411765 1.72348428808143 0.00465736579853356 0.0652031211794699 GO:0016651 oxidoreductase activity, acting on NAD(P)H 18/1988 88/18639 0.204545454545455 1.91776797146515 0.00487226363632313 0.0674365580572906 GO:0031369 translation initiation factor binding 9/1988 32/18639 0.28125 2.63693096076459 0.00503956765641292 0.06896846523046 GO:0140104 molecular carrier activity 40/1988 249/18639 0.160642570281124 1.50614530556835 0.00550894046360915 0.0745543276075104 GO:0097371 MDM2/MDM4 family protein binding 5/1988 12/18639 0.416666666666667 3.90656438631791 0.00571395150695259 0.0764790432469039 GO:0001540 amyloid-beta binding 17/1988 83/18639 0.204819277108434 1.92033526459965 0.00602848089075902 0.0795921693349034 GO:0140416 transcription regulator inhibitor activity 9/1988 33/18639 0.272727272727273 2.55702396195354 0.0062856493809381 0.0795921693349034 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 24/1988 132/18639 0.181818181818182 1.70468264130236 0.00630819379151711 0.0795921693349034 GO:0019001 guanyl nucleotide binding 59/1988 400/18639 0.1475 1.38292379275654 0.00633653263495084 0.0795921693349034 GO:0032561 guanyl ribonucleotide binding 59/1988 400/18639 0.1475 1.38292379275654 0.00633653263495084 0.0795921693349034 GO:0004857 enzyme inhibitor activity 61/1988 416/18639 0.146634615384615 1.37481015903111 0.00633862103898656 0.0795921693349034 GO:0042605 peptide antigen binding 11/1988 45/18639 0.244444444444444 2.29185110663984 0.00652014040447162 0.0810360307412901 GO:0072341 modified amino acid binding 18/1988 91/18639 0.197802197802198 1.85454485152674 0.00700097067045481 0.0861331543092319 GO:0051087 protein-folding chaperone binding 24/1988 134/18639 0.17910447761194 1.67923961680531 0.00762085804985521 0.0928220510472365 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 11/1988 46/18639 0.239130434782609 2.24202825649549 0.00776161273639277 0.0936004387418455 GO:0016835 carbon-oxygen lyase activity 16/1988 79/18639 0.20253164556962 1.89888699284313 0.00846004646210768 0.0992957372189838 GO:0005035 death receptor activity 5/1988 13/18639 0.384615384615385 3.60605943352422 0.00847845375268827 0.0992957372189838 GO:0009982 pseudouridine synthase activity 5/1988 13/18639 0.384615384615385 3.60605943352422 0.00847845375268827 0.0992957372189838 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 6/1988 18/18639 0.333333333333333 3.12525150905433 0.00874427905744321 0.100476715961942 GO:1901611 phosphatidylglycerol binding 6/1988 18/18639 0.333333333333333 3.12525150905433 0.00874427905744321 0.100476715961942 GO:0051861 glycolipid binding 8/1988 29/18639 0.275862068965517 2.58641504197599 0.00910968921301555 0.102696358004164 GO:0004521 RNA endonuclease activity 15/1988 73/18639 0.205479452054795 1.92652490284171 0.00926051384933584 0.102696358004164 GO:0043539 protein serine/threonine kinase activator activity 15/1988 73/18639 0.205479452054795 1.92652490284171 0.00926051384933584 0.102696358004164 GO:0140597 protein carrier chaperone 31/1988 188/18639 0.164893617021277 1.54600207628751 0.00927471213502303 0.102696358004164 GO:0001530 lipopolysaccharide binding 10/1988 41/18639 0.24390243902439 2.28676939686902 0.00945007500832718 0.102769565715558 GO:0140318 protein transporter activity 10/1988 41/18639 0.24390243902439 2.28676939686902 0.00945007500832718 0.102769565715558 GO:0001221 transcription coregulator binding 21/1988 115/18639 0.182608695652174 1.7120943049602 0.00968068134219724 0.104345751104391 GO:0016798 hydrolase activity, acting on glycosyl bonds 23/1988 130/18639 0.176923076923077 1.65878733942114 0.0102507711701535 0.109521397239008 GO:0015026 coreceptor activity 13/1988 61/18639 0.213114754098361 1.99811162054293 0.010954393837806 0.116021319082153 GO:0016859 cis-trans isomerase activity 10/1988 42/18639 0.238095238095238 2.23232250646738 0.0112459822366363 0.116349413074776 GO:0055106 ubiquitin-protein transferase regulator activity 9/1988 36/18639 0.25 2.34393863179074 0.0114629963620469 0.116349413074776 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 9/1988 36/18639 0.25 2.34393863179074 0.0114629963620469 0.116349413074776 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 9/1988 36/18639 0.25 2.34393863179074 0.0114629963620469 0.116349413074776 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 9/1988 36/18639 0.25 2.34393863179074 0.0114629963620469 0.116349413074776 GO:0031404 chloride ion binding 5/1988 14/18639 0.357142857142857 3.34848375970106 0.0120464944925449 0.120497936960709 GO:0061135 endopeptidase regulator activity 30/1988 184/18639 0.16304347826087 1.52865562942875 0.0120695798926162 0.120497936960709 GO:0002039 p53 binding 14/1988 69/18639 0.202898550724638 1.90232700551133 0.0130507424589014 0.129234181422292 GO:0019887 protein kinase regulator activity 39/1988 255/18639 0.152941176470588 1.43393892768375 0.01339559125649 0.131579275406491 GO:0008135 translation factor activity, RNA binding 16/1988 83/18639 0.192771084337349 1.80737436668202 0.0135274815460288 0.131811780184505 GO:0180051 translation factor activity 16/1988 84/18639 0.19047619047619 1.7858580051739 0.0151044368592556 0.140653086978327 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 6/1988 20/18639 0.3 2.81272635814889 0.0151661600312752 0.140653086978327 GO:0005539 glycosaminoglycan binding 37/1988 242/18639 0.152892561983471 1.43348313018607 0.015747881306125 0.140653086978327 GO:0005031 tumor necrosis factor receptor activity 4/1988 10/18639 0.4 3.75030181086519 0.0159750623857975 0.140653086978327 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 4/1988 10/18639 0.4 3.75030181086519 0.0159750623857975 0.140653086978327 GO:0031996 thioesterase binding 4/1988 10/18639 0.4 3.75030181086519 0.0159750623857975 0.140653086978327 GO:0033204 ribonuclease P RNA binding 4/1988 10/18639 0.4 3.75030181086519 0.0159750623857975 0.140653086978327 GO:0097177 mitochondrial ribosome binding 4/1988 10/18639 0.4 3.75030181086519 0.0159750623857975 0.140653086978327 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 22/1988 128/18639 0.171875 1.61145780935614 0.0163501790756659 0.140653086978327 GO:0043531 ADP binding 9/1988 38/18639 0.236842105263158 2.22057344064386 0.0163556143825814 0.140653086978327 GO:0050750 low-density lipoprotein particle receptor binding 7/1988 26/18639 0.269230769230769 2.52424160346696 0.0165022518568801 0.140653086978327 GO:0070006 metalloaminopeptidase activity 7/1988 26/18639 0.269230769230769 2.52424160346696 0.0165022518568801 0.140653086978327 GO:0000774 adenyl-nucleotide exchange factor activity 5/1988 15/18639 0.333333333333333 3.12525150905433 0.0165099075174991 0.140653086978327 GO:0004129 cytochrome-c oxidase activity 5/1988 15/18639 0.333333333333333 3.12525150905433 0.0165099075174991 0.140653086978327 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 5/1988 15/18639 0.333333333333333 3.12525150905433 0.0165099075174991 0.140653086978327 GO:0050700 CARD domain binding 5/1988 15/18639 0.333333333333333 3.12525150905433 0.0165099075174991 0.140653086978327 GO:0055105 ubiquitin-protein transferase inhibitor activity 5/1988 15/18639 0.333333333333333 3.12525150905433 0.0165099075174991 0.140653086978327 GO:0071813 lipoprotein particle binding 8/1988 32/18639 0.25 2.34393863179074 0.0167495891959283 0.140653086978327 GO:0071814 protein-lipid complex binding 8/1988 32/18639 0.25 2.34393863179074 0.0167495891959283 0.140653086978327 GO:0120015 sterol transfer activity 8/1988 32/18639 0.25 2.34393863179074 0.0167495891959283 0.140653086978327 GO:0004540 RNA nuclease activity 21/1988 121/18639 0.173553719008264 1.62719706669771 0.0168598938414086 0.140653086978327 GO:0003924 GTPase activity 48/1988 331/18639 0.145015105740181 1.35962603415052 0.017117970257085 0.141380070722723 GO:0044325 transmembrane transporter binding 23/1988 136/18639 0.169117647058824 1.58560554503492 0.0171791875755032 0.141380070722723 GO:0019955 cytokine binding 24/1988 144/18639 0.166666666666667 1.56262575452716 0.0179285753573864 0.146557079095951 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 9/1988 39/18639 0.230769230769231 2.16363566011453 0.0193059025931407 0.156763929056302 GO:0005496 steroid binding 19/1988 108/18639 0.175925925925926 1.64943829644534 0.0194871215684971 0.157187510400195 GO:0004364 glutathione transferase activity 7/1988 27/18639 0.259259259259259 2.43075117370892 0.0202788839194588 0.161435821005888 GO:0008320 protein transmembrane transporter activity 7/1988 27/18639 0.259259259259259 2.43075117370892 0.0202788839194588 0.161435821005888 GO:0008237 metallopeptidase activity 29/1988 184/18639 0.157608695652174 1.47770044178112 0.0206391139791123 0.162611825388693 GO:0008235 metalloexopeptidase activity 13/1988 66/18639 0.196969696969697 1.84673952807756 0.0207310928223993 0.162611825388693 GO:0000049 tRNA binding 15/1988 80/18639 0.1875 1.75795397384306 0.0208891779707664 0.162611825388693 GO:0031072 heat shock protein binding 22/1988 131/18639 0.16793893129771 1.57455419540142 0.0209606375911534 0.162611825388693 GO:0000062 fatty-acyl-CoA binding 5/1988 16/18639 0.3125 2.92992328973843 0.0219483195480361 0.163946872196872 GO:0008142 oxysterol binding 5/1988 16/18639 0.3125 2.92992328973843 0.0219483195480361 0.163946872196872 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/1988 16/18639 0.3125 2.92992328973843 0.0219483195480361 0.163946872196872 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 5/1988 16/18639 0.3125 2.92992328973843 0.0219483195480361 0.163946872196872 GO:0004177 aminopeptidase activity 9/1988 40/18639 0.225 2.10954476861167 0.0226226436156182 0.163946872196872 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 9/1988 40/18639 0.225 2.10954476861167 0.0226226436156182 0.163946872196872 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 12/1988 60/18639 0.2 1.8751509054326 0.0229565552203003 0.163946872196872 GO:0003953 NAD+ nucleosidase activity 4/1988 11/18639 0.363636363636364 3.40936528260472 0.0230171717123687 0.163946872196872 GO:0005536 D-glucose binding 4/1988 11/18639 0.363636363636364 3.40936528260472 0.0230171717123687 0.163946872196872 GO:0032794 GTPase activating protein binding 4/1988 11/18639 0.363636363636364 3.40936528260472 0.0230171717123687 0.163946872196872 GO:0034511 U3 snoRNA binding 4/1988 11/18639 0.363636363636364 3.40936528260472 0.0230171717123687 0.163946872196872 GO:0048185 activin binding 4/1988 11/18639 0.363636363636364 3.40936528260472 0.0230171717123687 0.163946872196872 GO:0097493 structural molecule activity conferring elasticity 4/1988 11/18639 0.363636363636364 3.40936528260472 0.0230171717123687 0.163946872196872 GO:1990948 ubiquitin ligase inhibitor activity 4/1988 11/18639 0.363636363636364 3.40936528260472 0.0230171717123687 0.163946872196872 GO:0050840 extracellular matrix binding 13/1988 67/18639 0.194029850746269 1.81917625153909 0.0232910569332854 0.16493318223687 GO:0008649 rRNA methyltransferase activity 6/1988 22/18639 0.272727272727273 2.55702396195354 0.0242770885865086 0.168008488058906 GO:0034062 5'-3' RNA polymerase activity 6/1988 22/18639 0.272727272727273 2.55702396195354 0.0242770885865086 0.168008488058906 GO:0070034 telomerase RNA binding 6/1988 22/18639 0.272727272727273 2.55702396195354 0.0242770885865086 0.168008488058906 GO:0097747 RNA polymerase activity 6/1988 22/18639 0.272727272727273 2.55702396195354 0.0242770885865086 0.168008488058906 GO:0003925 G protein activity 11/1988 54/18639 0.203703703703704 1.90987592219987 0.0253449816008994 0.173428020167952 GO:0051287 NAD binding 11/1988 54/18639 0.203703703703704 1.90987592219987 0.0253449816008994 0.173428020167952 GO:0008201 heparin binding 27/1988 172/18639 0.156976744186047 1.47177541996163 0.02601801481005 0.177038782338776 GO:0016757 glycosyltransferase activity 39/1988 267/18639 0.146067415730337 1.3694922343047 0.0264051343985185 0.178674742763308 GO:0004549 tRNA-specific ribonuclease activity 5/1988 17/18639 0.294117647058824 2.75757486093029 0.0284274171648279 0.188177141884568 GO:0030169 low-density lipoprotein particle binding 5/1988 17/18639 0.294117647058824 2.75757486093029 0.0284274171648279 0.188177141884568 GO:0032977 membrane insertase activity 5/1988 17/18639 0.294117647058824 2.75757486093029 0.0284274171648279 0.188177141884568 GO:1901567 fatty acid derivative binding 5/1988 17/18639 0.294117647058824 2.75757486093029 0.0284274171648279 0.188177141884568 GO:0004629 phospholipase C activity 7/1988 29/18639 0.241379310344828 2.26311316172899 0.0295521095252985 0.194564699469262 GO:0099186 structural constituent of postsynapse 6/1988 23/18639 0.260869565217391 2.44584900708599 0.0299636492984703 0.195164303986828 GO:0140102 catalytic activity, acting on a rRNA 6/1988 23/18639 0.260869565217391 2.44584900708599 0.0299636492984703 0.195164303986828 GO:0042056 chemoattractant activity 9/1988 42/18639 0.214285714285714 2.00909025582064 0.0304405502545412 0.195465708738064 GO:0051879 Hsp90 protein binding 9/1988 42/18639 0.214285714285714 2.00909025582064 0.0304405502545412 0.195465708738064 GO:0004526 ribonuclease P activity 4/1988 12/18639 0.333333333333333 3.12525150905433 0.0316687818150768 0.195465708738064 GO:0005165 neurotrophin receptor binding 4/1988 12/18639 0.333333333333333 3.12525150905433 0.0316687818150768 0.195465708738064 GO:0008179 adenylate cyclase binding 4/1988 12/18639 0.333333333333333 3.12525150905433 0.0316687818150768 0.195465708738064 GO:0016840 carbon-nitrogen lyase activity 4/1988 12/18639 0.333333333333333 3.12525150905433 0.0316687818150768 0.195465708738064 GO:0035251 UDP-glucosyltransferase activity 4/1988 12/18639 0.333333333333333 3.12525150905433 0.0316687818150768 0.195465708738064 GO:0035259 nuclear glucocorticoid receptor binding 4/1988 12/18639 0.333333333333333 3.12525150905433 0.0316687818150768 0.195465708738064 GO:0070008 serine-type exopeptidase activity 4/1988 12/18639 0.333333333333333 3.12525150905433 0.0316687818150768 0.195465708738064 GO:0016763 pentosyltransferase activity 10/1988 49/18639 0.204081632653061 1.91341929125775 0.0317752137357445 0.195465708738064 GO:0060590 ATPase regulator activity 10/1988 49/18639 0.204081632653061 1.91341929125775 0.0317752137357445 0.195465708738064 GO:0016741 transferase activity, transferring one-carbon groups 32/1988 215/18639 0.148837209302326 1.39546113892658 0.0327764336426945 0.200611538576894 GO:0001968 fibronectin binding 7/1988 30/18639 0.233333333333333 2.18767605633803 0.0351114372630989 0.21193036928973 GO:0016769 transferase activity, transferring nitrogenous groups 7/1988 30/18639 0.233333333333333 2.18767605633803 0.0351114372630989 0.21193036928973 GO:0043130 ubiquitin binding 17/1988 100/18639 0.17 1.59387826961771 0.0351477295537975 0.21193036928973 GO:0022804 active transmembrane transporter activity 61/1988 457/18639 0.133479212253829 1.25146832857099 0.0387181711306238 0.232309026783743 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 48/1988 349/18639 0.137535816618911 1.28950205531181 0.0395528489742616 0.236153774758091 GO:1990782 protein tyrosine kinase binding 19/1988 117/18639 0.162393162393162 1.522558427488 0.0410476967657919 0.243883388588949 GO:0070325 lipoprotein particle receptor binding 7/1988 31/18639 0.225806451612903 2.11710586097229 0.0413208320199466 0.244314433982014 GO:0019209 kinase activator activity 23/1988 148/18639 0.155405405405405 1.45704293327533 0.041571809307088 0.244610935922865 GO:0008035 high-density lipoprotein particle binding 4/1988 13/18639 0.307692307692308 2.88484754681938 0.0419755942872495 0.245799393470528 GO:0019211 phosphatase activator activity 6/1988 25/18639 0.24 2.25018108651911 0.0437841165548456 0.255162937625847 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 5/1988 19/18639 0.263157894736842 2.46730382293763 0.0446947369678841 0.255578355055788 GO:0046527 glucosyltransferase activity 5/1988 19/18639 0.263157894736842 2.46730382293763 0.0446947369678841 0.255578355055788 GO:0070003 threonine-type peptidase activity 5/1988 19/18639 0.263157894736842 2.46730382293763 0.0446947369678841 0.255578355055788 GO:0120227 acyl-CoA binding 5/1988 19/18639 0.263157894736842 2.46730382293763 0.0446947369678841 0.255578355055788 GO:0008009 chemokine activity 9/1988 45/18639 0.2 1.8751509054326 0.045408831098684 0.256652846764571 GO:0051539 4 iron, 4 sulfur cluster binding 9/1988 45/18639 0.2 1.8751509054326 0.045408831098684 0.256652846764571 GO:0001786 phosphatidylserine binding 11/1988 59/18639 0.186440677966102 1.74802203048801 0.0455147905592342 0.256652846764571 GO:0022884 macromolecule transmembrane transporter activity 7/1988 32/18639 0.21875 2.0509463028169 0.0482007800106717 0.270546313608287 GO:0016776 phosphotransferase activity, phosphate group as acceptor 8/1988 39/18639 0.205128205128205 1.92323169787959 0.050463166743687 0.281945582999132 GO:0140296 general transcription initiation factor binding 10/1988 53/18639 0.188679245283019 1.76901028814396 0.0512607892043488 0.2850942522872 GO:0004435 phosphatidylinositol phospholipase C activity 6/1988 26/18639 0.230769230769231 2.16363566011453 0.0519686759642353 0.285125438398372 GO:0005160 transforming growth factor beta receptor binding 6/1988 26/18639 0.230769230769231 2.16363566011453 0.0519686759642353 0.285125438398372 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 6/1988 26/18639 0.230769230769231 2.16363566011453 0.0519686759642353 0.285125438398372 GO:0016779 nucleotidyltransferase activity 21/1988 136/18639 0.154411764705882 1.4477268019884 0.0527256956836399 0.287981602433513 GO:0019210 kinase inhibitor activity 15/1988 90/18639 0.166666666666667 1.56262575452716 0.0531523559892585 0.289015935691593 GO:0032036 myosin heavy chain binding 4/1988 14/18639 0.285714285714286 2.67878700776085 0.0539472342051314 0.290073326913301 GO:1901612 cardiolipin binding 4/1988 14/18639 0.285714285714286 2.67878700776085 0.0539472342051314 0.290073326913301 GO:1990841 promoter-specific chromatin binding 12/1988 68/18639 0.176470588235294 1.65454491655817 0.0544999050080342 0.290073326913301 GO:0016505 peptidase activator activity involved in apoptotic process 5/1988 20/18639 0.25 2.34393863179074 0.0545375959467536 0.290073326913301 GO:0043024 ribosomal small subunit binding 5/1988 20/18639 0.25 2.34393863179074 0.0545375959467536 0.290073326913301 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 7/1988 33/18639 0.212121212121212 1.98879641485275 0.0557668996459651 0.294043652678725 GO:0071889 14-3-3 protein binding 7/1988 33/18639 0.212121212121212 1.98879641485275 0.0557668996459651 0.294043652678725 GO:0016836 hydro-lyase activity 11/1988 61/18639 0.180327868852459 1.69070983276709 0.0560091495215285 0.294048034988025 GO:0017069 snRNA binding 10/1988 54/18639 0.185185185185185 1.73625083836351 0.0571507454778601 0.298244852813358 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 8/1988 40/18639 0.2 1.8751509054326 0.0574232975257042 0.298244852813358 GO:0098631 cell adhesion mediator activity 13/1988 76/18639 0.171052631578947 1.60374748490946 0.0576951722426658 0.298244852813358 GO:0005126 cytokine receptor binding 38/1988 275/18639 0.138181818181818 1.29555880738979 0.0577880010377279 0.298244852813358 GO:0004860 protein kinase inhibitor activity 14/1988 84/18639 0.166666666666667 1.56262575452716 0.0602848672545385 0.309818431713198 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 6/1988 27/18639 0.222222222222222 2.08350100603622 0.0610229022627429 0.312293676285802 GO:0030295 protein kinase activator activity 21/1988 139/18639 0.151079136690647 1.41648089978721 0.0638612434816082 0.324951186885473 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 7/1988 34/18639 0.205882352941176 1.9303024026512 0.0640297905193051 0.324951186885473 GO:0008373 sialyltransferase activity 5/1988 21/18639 0.238095238095238 2.23232250646738 0.0655307885170094 0.325782327261556 GO:0019200 carbohydrate kinase activity 5/1988 21/18639 0.238095238095238 2.23232250646738 0.0655307885170094 0.325782327261556 GO:0035613 RNA stem-loop binding 5/1988 21/18639 0.238095238095238 2.23232250646738 0.0655307885170094 0.325782327261556 GO:0072542 protein phosphatase activator activity 5/1988 21/18639 0.238095238095238 2.23232250646738 0.0655307885170094 0.325782327261556 GO:0097110 scaffold protein binding 12/1988 70/18639 0.171428571428571 1.60727220465651 0.0655309278974395 0.325782327261556 GO:0003714 transcription corepressor activity 29/1988 204/18639 0.142156862745098 1.33282784944964 0.0662845306663567 0.326860560128026 GO:0008168 methyltransferase activity 29/1988 204/18639 0.142156862745098 1.33282784944964 0.0662845306663567 0.326860560128026 GO:0004467 long-chain fatty acid-CoA ligase activity 4/1988 15/18639 0.266666666666667 2.50020120724346 0.0675608075460885 0.329156254364543 GO:0015556 C4-dicarboxylate transmembrane transporter activity 4/1988 15/18639 0.266666666666667 2.50020120724346 0.0675608075460885 0.329156254364543 GO:0140776 protein-containing complex destabilizing activity 4/1988 15/18639 0.266666666666667 2.50020120724346 0.0675608075460885 0.329156254364543 GO:0050660 flavin adenine dinucleotide binding 14/1988 86/18639 0.162790697674419 1.52628562070095 0.0708018235642273 0.340232403684425 GO:0016866 intramolecular transferase activity 6/1988 28/18639 0.214285714285714 2.00909025582064 0.0709515850047981 0.340232403684425 GO:0051019 mitogen-activated protein kinase binding 6/1988 28/18639 0.214285714285714 2.00909025582064 0.0709515850047981 0.340232403684425 GO:0097718 disordered domain specific binding 6/1988 28/18639 0.214285714285714 2.00909025582064 0.0709515850047981 0.340232403684425 GO:0001222 transcription corepressor binding 9/1988 49/18639 0.183673469387755 1.72207736213198 0.0720041216236679 0.343925569167167 GO:0033293 monocarboxylic acid binding 13/1988 79/18639 0.164556962025316 1.54284568168505 0.0743376532573908 0.353684615888679 GO:0004222 metalloendopeptidase activity 17/1988 110/18639 0.154545454545455 1.44898024510701 0.0750012099159397 0.355453204971263 GO:0019842 vitamin binding 22/1988 150/18639 0.146666666666667 1.3751106639839 0.0764518359501293 0.360923783671541 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 5/1988 22/18639 0.227272727272727 2.13085330162795 0.077664229673039 0.362433071807515 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/1988 22/18639 0.227272727272727 2.13085330162795 0.077664229673039 0.362433071807515 GO:0140517 protein-RNA adaptor activity 5/1988 22/18639 0.227272727272727 2.13085330162795 0.077664229673039 0.362433071807515 GO:0004722 protein serine/threonine phosphatase activity 16/1988 103/18639 0.155339805825243 1.45642788771464 0.0793231216328666 0.365245412022989 GO:0004955 prostaglandin receptor activity 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0008190 eukaryotic initiation factor 4E binding 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0008239 dipeptidyl-peptidase activity 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0030957 Tat protein binding 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0031434 mitogen-activated protein kinase kinase binding 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0032395 MHC class II receptor activity 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0043295 glutathione binding 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0051880 G-quadruplex DNA binding 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0140940 histone H2A methyltransferase activity 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:1990259 histone H2AQ104 methyltransferase activity 3/1988 10/18639 0.3 2.81272635814889 0.0820644601916893 0.365245412022989 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 4/1988 16/18639 0.25 2.34393863179074 0.0827649702121059 0.365245412022989 GO:0017070 U6 snRNA binding 4/1988 16/18639 0.25 2.34393863179074 0.0827649702121059 0.365245412022989 GO:0031435 mitogen-activated protein kinase kinase kinase binding 4/1988 16/18639 0.25 2.34393863179074 0.0827649702121059 0.365245412022989 GO:0004518 nuclease activity 29/1988 209/18639 0.138755980861244 1.30094201573075 0.0844170611821412 0.369204746693854 GO:0032182 ubiquitin-like protein binding 18/1988 120/18639 0.15 1.40636317907445 0.0859681223259263 0.369204746693854 GO:0019838 growth factor binding 20/1988 136/18639 0.147058823529412 1.37878743046514 0.0860665734679716 0.369204746693854 GO:0033192 calmodulin-dependent protein phosphatase activity 13/1988 81/18639 0.160493827160494 1.50475072658171 0.0869965207726897 0.369204746693854 GO:0140791 histone H2AXS140 phosphatase activity 13/1988 81/18639 0.160493827160494 1.50475072658171 0.0869965207726897 0.369204746693854 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 13/1988 81/18639 0.160493827160494 1.50475072658171 0.0869965207726897 0.369204746693854 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 13/1988 81/18639 0.160493827160494 1.50475072658171 0.0869965207726897 0.369204746693854 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 13/1988 81/18639 0.160493827160494 1.50475072658171 0.0869965207726897 0.369204746693854 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 13/1988 81/18639 0.160493827160494 1.50475072658171 0.0869965207726897 0.369204746693854 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 13/1988 81/18639 0.160493827160494 1.50475072658171 0.0869965207726897 0.369204746693854 GO:1990439 MAP kinase serine/threonine phosphatase activity 13/1988 81/18639 0.160493827160494 1.50475072658171 0.0869965207726897 0.369204746693854 GO:0004022 alcohol dehydrogenase (NAD+) activity 5/1988 23/18639 0.217391304347826 2.038207505905 0.0909143908881971 0.377368375699575 GO:0005158 insulin receptor binding 5/1988 23/18639 0.217391304347826 2.038207505905 0.0909143908881971 0.377368375699575 GO:0008171 O-methyltransferase activity 5/1988 23/18639 0.217391304347826 2.038207505905 0.0909143908881971 0.377368375699575 GO:0016849 phosphorus-oxygen lyase activity 5/1988 23/18639 0.217391304347826 2.038207505905 0.0909143908881971 0.377368375699575 GO:0017134 fibroblast growth factor binding 5/1988 23/18639 0.217391304347826 2.038207505905 0.0909143908881971 0.377368375699575 GO:0031681 G-protein beta-subunit binding 5/1988 23/18639 0.217391304347826 2.038207505905 0.0909143908881971 0.377368375699575 GO:0019205 nucleobase-containing compound kinase activity 8/1988 44/18639 0.181818181818182 1.70468264130236 0.0910889182723113 0.377368375699575 GO:0098918 structural constituent of synapse 6/1988 30/18639 0.2 1.8751509054326 0.0934114509009293 0.38468270428906 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 13/1988 82/18639 0.158536585365854 1.48640010796486 0.0938019402084161 0.38468270428906 GO:0033549 MAP kinase phosphatase activity 13/1988 82/18639 0.158536585365854 1.48640010796486 0.0938019402084161 0.38468270428906 GO:0008173 RNA methyltransferase activity 11/1988 67/18639 0.164179104477612 1.53930298207153 0.0966013693489833 0.394833784788798 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 9/1988 52/18639 0.173076923076923 1.6227267450859 0.0971836585892783 0.39588527144395 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/1988 17/18639 0.235294117647059 2.20605988874423 0.0994842173035761 0.398591370643933 GO:0004659 prenyltransferase activity 4/1988 17/18639 0.235294117647059 2.20605988874423 0.0994842173035761 0.398591370643933 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 4/1988 17/18639 0.235294117647059 2.20605988874423 0.0994842173035761 0.398591370643933 GO:0016018 cyclosporin A binding 4/1988 17/18639 0.235294117647059 2.20605988874423 0.0994842173035761 0.398591370643933 GO:0048038 quinone binding 4/1988 17/18639 0.235294117647059 2.20605988874423 0.0994842173035761 0.398591370643933 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 13/1988 83/18639 0.156626506024096 1.46849167292914 0.100925545576297 0.40304037544895 GO:0051020 GTPase binding 41/1988 315/18639 0.13015873015873 1.2203363035355 0.104097881605175 0.405509142256892 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 3/1988 11/18639 0.272727272727273 2.55702396195354 0.104207193371434 0.405509142256892 GO:0004954 prostanoid receptor activity 3/1988 11/18639 0.272727272727273 2.55702396195354 0.104207193371434 0.405509142256892 GO:0008503 benzodiazepine receptor activity 3/1988 11/18639 0.272727272727273 2.55702396195354 0.104207193371434 0.405509142256892 GO:0015173 aromatic amino acid transmembrane transporter activity 3/1988 11/18639 0.272727272727273 2.55702396195354 0.104207193371434 0.405509142256892 GO:0047676 arachidonate-CoA ligase activity 3/1988 11/18639 0.272727272727273 2.55702396195354 0.104207193371434 0.405509142256892 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 3/1988 11/18639 0.272727272727273 2.55702396195354 0.104207193371434 0.405509142256892 GO:1900750 oligopeptide binding 3/1988 11/18639 0.272727272727273 2.55702396195354 0.104207193371434 0.405509142256892 GO:0050699 WW domain binding 5/1988 24/18639 0.208333333333333 1.95328219315895 0.105245493799981 0.40694924269326 GO:0070300 phosphatidic acid binding 5/1988 24/18639 0.208333333333333 1.95328219315895 0.105245493799981 0.40694924269326 GO:0016411 acylglycerol O-acyltransferase activity 6/1988 31/18639 0.193548387096774 1.81466216654767 0.105913199432365 0.408235053508293 GO:0017018 myosin phosphatase activity 13/1988 84/18639 0.154761904761905 1.45100962920379 0.108366796536619 0.416374631487703 GO:0052689 carboxylic ester hydrolase activity 14/1988 92/18639 0.152173913043478 1.4267452541335 0.109245523875198 0.418430968805004 GO:0003724 RNA helicase activity 12/1988 77/18639 0.155844155844156 1.46115654968774 0.115033306014581 0.43921807751022 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/1988 18/18639 0.222222222222222 2.08350100603622 0.117623177990759 0.446308507142505 GO:0004706 JUN kinase kinase kinase activity 4/1988 18/18639 0.222222222222222 2.08350100603622 0.117623177990759 0.446308507142505 GO:0004175 endopeptidase activity 51/1988 405/18639 0.125925925925926 1.18065057008719 0.118694286508898 0.447351586110939 GO:0008378 galactosyltransferase activity 6/1988 32/18639 0.1875 1.75795397384306 0.11923145006814 0.447351586110939 GO:0051059 NF-kappaB binding 6/1988 32/18639 0.1875 1.75795397384306 0.11923145006814 0.447351586110939 GO:0001848 complement binding 5/1988 25/18639 0.2 1.8751509054326 0.120610838111265 0.447351586110939 GO:0004709 MAP kinase kinase kinase activity 5/1988 25/18639 0.2 1.8751509054326 0.120610838111265 0.447351586110939 GO:0008483 transaminase activity 5/1988 25/18639 0.2 1.8751509054326 0.120610838111265 0.447351586110939 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/1988 25/18639 0.2 1.8751509054326 0.120610838111265 0.447351586110939 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 23/1988 167/18639 0.137724550898204 1.29127158158532 0.120836347972495 0.447351586110939 GO:0051015 actin filament binding 28/1988 209/18639 0.133971291866029 1.25608194622279 0.121964100843572 0.450158408568092 GO:0005504 fatty acid binding 8/1988 47/18639 0.170212765957447 1.59587311100646 0.122430199344963 0.450513543208959 GO:0008514 organic anion transmembrane transporter activity 35/1988 269/18639 0.130111524163569 1.21989371171266 0.125275724465338 0.451497256011628 GO:0008374 O-acyltransferase activity 9/1988 55/18639 0.163636363636364 1.53421437717212 0.126830955127639 0.451497256011628 GO:0004532 RNA exonuclease activity 7/1988 40/18639 0.175 1.64075704225352 0.128198947085213 0.451497256011628 GO:0061791 GTPase motor activity 7/1988 40/18639 0.175 1.64075704225352 0.128198947085213 0.451497256011628 GO:0071949 FAD binding 7/1988 40/18639 0.175 1.64075704225352 0.128198947085213 0.451497256011628 GO:1990606 membrane scission GTPase motor activity 7/1988 40/18639 0.175 1.64075704225352 0.128198947085213 0.451497256011628 GO:0004000 adenosine deaminase activity 3/1988 12/18639 0.25 2.34393863179074 0.128386663890221 0.451497256011628 GO:0004300 enoyl-CoA hydratase activity 3/1988 12/18639 0.25 2.34393863179074 0.128386663890221 0.451497256011628 GO:0004859 phospholipase inhibitor activity 3/1988 12/18639 0.25 2.34393863179074 0.128386663890221 0.451497256011628 GO:0016208 AMP binding 3/1988 12/18639 0.25 2.34393863179074 0.128386663890221 0.451497256011628 GO:0016273 arginine N-methyltransferase activity 3/1988 12/18639 0.25 2.34393863179074 0.128386663890221 0.451497256011628 GO:0016274 protein-arginine N-methyltransferase activity 3/1988 12/18639 0.25 2.34393863179074 0.128386663890221 0.451497256011628 GO:0036009 protein-glutamine N-methyltransferase activity 3/1988 12/18639 0.25 2.34393863179074 0.128386663890221 0.451497256011628 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 3/1988 12/18639 0.25 2.34393863179074 0.128386663890221 0.451497256011628 GO:0097677 STAT family protein binding 3/1988 12/18639 0.25 2.34393863179074 0.128386663890221 0.451497256011628 GO:0004519 endonuclease activity 18/1988 127/18639 0.141732283464567 1.32884709833806 0.128628528601014 0.451497256011628 GO:0003779 actin binding 55/1988 443/18639 0.124153498871332 1.16403272910601 0.130277666116937 0.454981376424148 GO:0140674 ATP-dependent histone chaperone activity 21/1988 152/18639 0.138157894736842 1.29533450704225 0.130368226906427 0.454981376424148 GO:0016887 ATP hydrolysis activity 52/1988 417/18639 0.124700239808153 1.1691588379196 0.130821748168413 0.455259683626077 GO:0008186 ATP-dependent activity, acting on RNA 12/1988 79/18639 0.151898734177215 1.42416524463235 0.132302177894539 0.458636044080469 GO:0030414 peptidase inhibitor activity 23/1988 169/18639 0.136094674556213 1.27599026109319 0.132545063642303 0.458636044080469 GO:0004866 endopeptidase inhibitor activity 22/1988 161/18639 0.136645962732919 1.28115900371171 0.134656966500776 0.464623754101826 GO:0031490 chromatin DNA binding 18/1988 128/18639 0.140625 1.31846548038229 0.135585004513172 0.465047878654522 GO:0001664 G protein-coupled receptor binding 38/1988 297/18639 0.127946127946128 1.19959148832388 0.135788332194738 0.465047878654522 GO:0051139 metal cation:proton antiporter activity 5/1988 26/18639 0.192307692307692 1.80302971676211 0.136954210051034 0.465047878654522 GO:0070412 R-SMAD binding 5/1988 26/18639 0.192307692307692 1.80302971676211 0.136954210051034 0.465047878654522 GO:0005520 insulin-like growth factor binding 4/1988 19/18639 0.210526315789474 1.9738430583501 0.137070762263525 0.465047878654522 GO:0050145 nucleoside monophosphate kinase activity 4/1988 19/18639 0.210526315789474 1.9738430583501 0.137070762263525 0.465047878654522 GO:0042379 chemokine receptor binding 11/1988 72/18639 0.152777777777778 1.4324069416499 0.141047504149388 0.475149142877277 GO:0004812 aminoacyl-tRNA ligase activity 7/1988 41/18639 0.170731707317073 1.60073857780831 0.141218382365825 0.475149142877277 GO:0016875 ligase activity, forming carbon-oxygen bonds 7/1988 41/18639 0.170731707317073 1.60073857780831 0.141218382365825 0.475149142877277 GO:0046982 protein heterodimerization activity 46/1988 369/18639 0.124661246612466 1.16879324728861 0.147955597883368 0.492431982964743 GO:0008175 tRNA methyltransferase activity 6/1988 34/18639 0.176470588235294 1.65454491655817 0.148185731990145 0.492431982964743 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 6/1988 34/18639 0.176470588235294 1.65454491655817 0.148185731990145 0.492431982964743 GO:0090482 vitamin transmembrane transporter activity 6/1988 34/18639 0.176470588235294 1.65454491655817 0.148185731990145 0.492431982964743 GO:0070279 vitamin B6 binding 9/1988 57/18639 0.157894736842105 1.48038229376258 0.148973927048335 0.492431982964743 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 18/1988 130/18639 0.138461538461538 1.29818139606872 0.150130667346031 0.492431982964743 GO:0038024 cargo receptor activity 10/1988 65/18639 0.153846153846154 1.44242377340969 0.150496320501885 0.492431982964743 GO:0030971 receptor tyrosine kinase binding 12/1988 81/18639 0.148148148148148 1.38900067069081 0.150910981242432 0.492431982964743 GO:0005385 zinc ion transmembrane transporter activity 5/1988 27/18639 0.185185185185185 1.73625083836351 0.154211325457464 0.492431982964743 GO:0016405 CoA-ligase activity 5/1988 27/18639 0.185185185185185 1.73625083836351 0.154211325457464 0.492431982964743 GO:0005172 vascular endothelial growth factor receptor binding 3/1988 13/18639 0.230769230769231 2.16363566011453 0.154309984771112 0.492431982964743 GO:0017154 semaphorin receptor activity 3/1988 13/18639 0.230769230769231 2.16363566011453 0.154309984771112 0.492431982964743 GO:0019104 DNA N-glycosylase activity 3/1988 13/18639 0.230769230769231 2.16363566011453 0.154309984771112 0.492431982964743 GO:0031994 insulin-like growth factor I binding 3/1988 13/18639 0.230769230769231 2.16363566011453 0.154309984771112 0.492431982964743 GO:0035673 oligopeptide transmembrane transporter activity 3/1988 13/18639 0.230769230769231 2.16363566011453 0.154309984771112 0.492431982964743 GO:0043560 insulin receptor substrate binding 3/1988 13/18639 0.230769230769231 2.16363566011453 0.154309984771112 0.492431982964743 GO:0061459 L-arginine transmembrane transporter activity 3/1988 13/18639 0.230769230769231 2.16363566011453 0.154309984771112 0.492431982964743 GO:0140410 monoatomic cation:bicarbonate symporter activity 3/1988 13/18639 0.230769230769231 2.16363566011453 0.154309984771112 0.492431982964743 GO:0008307 structural constituent of muscle 7/1988 42/18639 0.166666666666667 1.56262575452716 0.154845196613708 0.492431982964743 GO:0019894 kinesin binding 7/1988 42/18639 0.166666666666667 1.56262575452716 0.154845196613708 0.492431982964743 GO:0048487 beta-tubulin binding 7/1988 42/18639 0.166666666666667 1.56262575452716 0.154845196613708 0.492431982964743 GO:0000339 RNA cap binding 4/1988 20/18639 0.2 1.8751509054326 0.157704053842718 0.496339890388709 GO:0016408 C-acyltransferase activity 4/1988 20/18639 0.2 1.8751509054326 0.157704053842718 0.496339890388709 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/1988 20/18639 0.2 1.8751509054326 0.157704053842718 0.496339890388709 GO:0030742 GTP-dependent protein binding 4/1988 20/18639 0.2 1.8751509054326 0.157704053842718 0.496339890388709 GO:0000175 3'-5'-RNA exonuclease activity 6/1988 35/18639 0.171428571428571 1.60727220465651 0.163742442348722 0.51401622366171 GO:0140658 ATP-dependent chromatin remodeler activity 21/1988 158/18639 0.132911392405063 1.24614458905331 0.171285843561868 0.534033398685929 GO:0003743 translation initiation factor activity 8/1988 51/18639 0.156862745098039 1.47070659249615 0.171796278629286 0.534033398685929 GO:0003725 double-stranded RNA binding 11/1988 75/18639 0.146666666666667 1.3751106639839 0.172115879320907 0.534033398685929 GO:0046625 sphingolipid binding 5/1988 28/18639 0.178571428571429 1.67424187985053 0.17231126903413 0.534033398685929 GO:0051393 alpha-actinin binding 5/1988 28/18639 0.178571428571429 1.67424187985053 0.17231126903413 0.534033398685929 GO:0070888 E-box binding 9/1988 59/18639 0.152542372881356 1.43019984312656 0.172895029102739 0.534482602657707 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 4/1988 21/18639 0.19047619047619 1.7858580051739 0.179391880978179 0.539267184912293 GO:0005123 death receptor binding 4/1988 21/18639 0.19047619047619 1.7858580051739 0.179391880978179 0.539267184912293 GO:0015174 basic amino acid transmembrane transporter activity 4/1988 21/18639 0.19047619047619 1.7858580051739 0.179391880978179 0.539267184912293 GO:0036122 BMP binding 4/1988 21/18639 0.19047619047619 1.7858580051739 0.179391880978179 0.539267184912293 GO:0004033 aldo-keto reductase (NADPH) activity 6/1988 36/18639 0.166666666666667 1.56262575452716 0.17995835897115 0.539267184912293 GO:0044390 ubiquitin-like protein conjugating enzyme binding 6/1988 36/18639 0.166666666666667 1.56262575452716 0.17995835897115 0.539267184912293 GO:0008474 palmitoyl-(protein) hydrolase activity 3/1988 14/18639 0.214285714285714 2.00909025582064 0.181681644016379 0.539267184912293 GO:0016530 metallochaperone activity 3/1988 14/18639 0.214285714285714 2.00909025582064 0.181681644016379 0.539267184912293 GO:0019992 diacylglycerol binding 3/1988 14/18639 0.214285714285714 2.00909025582064 0.181681644016379 0.539267184912293 GO:0042043 neurexin family protein binding 3/1988 14/18639 0.214285714285714 2.00909025582064 0.181681644016379 0.539267184912293 GO:0043176 amine binding 3/1988 14/18639 0.214285714285714 2.00909025582064 0.181681644016379 0.539267184912293 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 3/1988 14/18639 0.214285714285714 2.00909025582064 0.181681644016379 0.539267184912293 GO:0098599 palmitoyl hydrolase activity 3/1988 14/18639 0.214285714285714 2.00909025582064 0.181681644016379 0.539267184912293 GO:1901474 azole transmembrane transporter activity 3/1988 14/18639 0.214285714285714 2.00909025582064 0.181681644016379 0.539267184912293 GO:0000510 H3-H4 histone complex chaperone activity 20/1988 151/18639 0.132450331125828 1.24182179167722 0.182412216899725 0.539267184912293 GO:0140584 chromatin extrusion motor activity 20/1988 151/18639 0.132450331125828 1.24182179167722 0.182412216899725 0.539267184912293 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 20/1988 151/18639 0.132450331125828 1.24182179167722 0.182412216899725 0.539267184912293 GO:0140849 ATP-dependent H2AZ histone chaperone activity 20/1988 151/18639 0.132450331125828 1.24182179167722 0.182412216899725 0.539267184912293 GO:0001046 core promoter sequence-specific DNA binding 7/1988 44/18639 0.159090909090909 1.49159731113956 0.18379898509563 0.539438949027657 GO:0001223 transcription coactivator binding 7/1988 44/18639 0.159090909090909 1.49159731113956 0.18379898509563 0.539438949027657 GO:0016790 thiolester hydrolase activity 7/1988 44/18639 0.159090909090909 1.49159731113956 0.18379898509563 0.539438949027657 GO:0030145 manganese ion binding 10/1988 68/18639 0.147058823529412 1.37878743046514 0.184639823102874 0.540463486009228 GO:0001098 basal transcription machinery binding 9/1988 60/18639 0.15 1.40636317907445 0.185479258745367 0.540463486009228 GO:0001099 basal RNA polymerase II transcription machinery binding 9/1988 60/18639 0.15 1.40636317907445 0.185479258745367 0.540463486009228 GO:0015616 DNA translocase activity 20/1988 152/18639 0.131578947368421 1.23365191146881 0.190297669929012 0.55318033883899 GO:0043236 laminin binding 5/1988 29/18639 0.172413793103448 1.616509401235 0.191177898380123 0.554415905302356 GO:0042826 histone deacetylase binding 17/1988 127/18639 0.133858267716535 1.2550222595415 0.193965049192521 0.561162541369335 GO:0042805 actinin binding 6/1988 37/18639 0.162162162162162 1.52039262602643 0.1967834132141 0.56796729216771 GO:0061775 cohesin loader activity 20/1988 153/18639 0.130718954248366 1.22558882708013 0.198350265874629 0.570476090841648 GO:0140789 histone phosphatase activity 18/1988 136/18639 0.132352941176471 1.24090868741863 0.198606287609396 0.570476090841648 GO:0046915 transition metal ion transmembrane transporter activity 7/1988 45/18639 0.155555555555556 1.45845070422535 0.199057749267406 0.570476090841648 GO:0008083 growth factor activity 21/1988 162/18639 0.12962962962963 1.21537558685446 0.20193689246356 0.577368861550742 GO:0016758 hexosyltransferase activity 25/1988 197/18639 0.126903553299492 1.18981656436078 0.206064955461914 0.58467104062169 GO:0016922 nuclear receptor binding 18/1988 137/18639 0.131386861313869 1.23185095977324 0.207348030077085 0.58467104062169 GO:0016782 transferase activity, transferring sulphur-containing groups 10/1988 70/18639 0.142857142857143 1.33939350388043 0.209176778011184 0.58467104062169 GO:0004559 alpha-mannosidase activity 3/1988 15/18639 0.2 1.8751509054326 0.210211853133952 0.58467104062169 GO:0004953 icosanoid receptor activity 3/1988 15/18639 0.2 1.8751509054326 0.210211853133952 0.58467104062169 GO:0005523 tropomyosin binding 3/1988 15/18639 0.2 1.8751509054326 0.210211853133952 0.58467104062169 GO:0008242 omega peptidase activity 3/1988 15/18639 0.2 1.8751509054326 0.210211853133952 0.58467104062169 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 3/1988 15/18639 0.2 1.8751509054326 0.210211853133952 0.58467104062169 GO:0016846 carbon-sulfur lyase activity 3/1988 15/18639 0.2 1.8751509054326 0.210211853133952 0.58467104062169 GO:0050780 dopamine receptor binding 3/1988 15/18639 0.2 1.8751509054326 0.210211853133952 0.58467104062169 GO:0140161 monocarboxylate:sodium symporter activity 3/1988 15/18639 0.2 1.8751509054326 0.210211853133952 0.58467104062169 GO:0015215 nucleotide transmembrane transporter activity 5/1988 30/18639 0.166666666666667 1.56262575452716 0.210731187875962 0.58467104062169 GO:0035925 mRNA 3'-UTR AU-rich region binding 5/1988 30/18639 0.166666666666667 1.56262575452716 0.210731187875962 0.58467104062169 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6/1988 38/18639 0.157894736842105 1.48038229376258 0.214164606862901 0.590546471071132 GO:0042887 amide transmembrane transporter activity 6/1988 38/18639 0.157894736842105 1.48038229376258 0.214164606862901 0.590546471071132 GO:0004180 carboxypeptidase activity 7/1988 46/18639 0.152173913043478 1.4267452541335 0.214788248509451 0.590546471071132 GO:0030291 protein serine/threonine kinase inhibitor activity 7/1988 46/18639 0.152173913043478 1.4267452541335 0.214788248509451 0.590546471071132 GO:0003697 single-stranded DNA binding 16/1988 121/18639 0.132231404958678 1.23976919367444 0.216854343605187 0.594884212862879 GO:0046332 SMAD binding 11/1988 79/18639 0.139240506329114 1.30548480757966 0.218108093861911 0.595882485380671 GO:0140713 histone chaperone activity 21/1988 164/18639 0.128048780487805 1.20055393335623 0.218196706469441 0.595882485380671 GO:0004896 cytokine receptor activity 13/1988 96/18639 0.135416666666667 1.26963342555332 0.220973778020501 0.602116468968613 GO:0042171 lysophosphatidic acid acyltransferase activity 4/1988 23/18639 0.173913043478261 1.630566004724 0.22538405409675 0.607598993686281 GO:0071617 lysophospholipid acyltransferase activity 4/1988 23/18639 0.173913043478261 1.630566004724 0.22538405409675 0.607598993686281 GO:0140103 catalytic activity, acting on a glycoprotein 4/1988 23/18639 0.173913043478261 1.630566004724 0.22538405409675 0.607598993686281 GO:0005507 copper ion binding 9/1988 63/18639 0.142857142857143 1.33939350388043 0.225480086326929 0.607598993686281 GO:1901682 sulfur compound transmembrane transporter activity 9/1988 63/18639 0.142857142857143 1.33939350388043 0.225480086326929 0.607598993686281 GO:0140313 molecular sequestering activity 8/1988 55/18639 0.145454545454545 1.36374611304189 0.228587974027911 0.614614022882994 GO:0008327 methyl-CpG binding 5/1988 31/18639 0.161290322580645 1.51221847212306 0.230888493345884 0.618070736033598 GO:0016878 acid-thiol ligase activity 5/1988 31/18639 0.161290322580645 1.51221847212306 0.230888493345884 0.618070736033598 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 12/1988 89/18639 0.134831460674157 1.26414667781973 0.237396543430284 0.624968768360966 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 12/1988 89/18639 0.134831460674157 1.26414667781973 0.237396543430284 0.624968768360966 GO:0004721 phosphoprotein phosphatase activity 22/1988 175/18639 0.125714285714286 1.17866628341477 0.237643567635476 0.624968768360966 GO:0005149 interleukin-1 receptor binding 3/1988 16/18639 0.1875 1.75795397384306 0.239622672269763 0.624968768360966 GO:0005159 insulin-like growth factor receptor binding 3/1988 16/18639 0.1875 1.75795397384306 0.239622672269763 0.624968768360966 GO:0015385 sodium:proton antiporter activity 3/1988 16/18639 0.1875 1.75795397384306 0.239622672269763 0.624968768360966 GO:0015923 mannosidase activity 3/1988 16/18639 0.1875 1.75795397384306 0.239622672269763 0.624968768360966 GO:0016722 oxidoreductase activity, acting on metal ions 3/1988 16/18639 0.1875 1.75795397384306 0.239622672269763 0.624968768360966 GO:0019841 retinol binding 3/1988 16/18639 0.1875 1.75795397384306 0.239622672269763 0.624968768360966 GO:0022841 potassium ion leak channel activity 3/1988 16/18639 0.1875 1.75795397384306 0.239622672269763 0.624968768360966 GO:0055102 lipase inhibitor activity 3/1988 16/18639 0.1875 1.75795397384306 0.239622672269763 0.624968768360966 GO:0097027 ubiquitin-protein transferase activator activity 3/1988 16/18639 0.1875 1.75795397384306 0.239622672269763 0.624968768360966 GO:0004725 protein tyrosine phosphatase activity 13/1988 98/18639 0.13265306122449 1.24372253931754 0.243404883734844 0.632997862819743 GO:0030170 pyridoxal phosphate binding 8/1988 56/18639 0.142857142857143 1.33939350388043 0.24374055637312 0.632997862819743 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 7/1988 48/18639 0.145833333333333 1.36729753521127 0.247504660021872 0.638200695752385 GO:0140793 histone H2AXY142 phosphatase activity 12/1988 90/18639 0.133333333333333 1.25010060362173 0.249375210698667 0.638200695752385 GO:0005315 phosphate transmembrane transporter activity 4/1988 24/18639 0.166666666666667 1.56262575452716 0.249411766156104 0.638200695752385 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 4/1988 24/18639 0.166666666666667 1.56262575452716 0.249411766156104 0.638200695752385 GO:0035035 histone acetyltransferase binding 4/1988 24/18639 0.166666666666667 1.56262575452716 0.249411766156104 0.638200695752385 GO:0050431 transforming growth factor beta binding 4/1988 24/18639 0.166666666666667 1.56262575452716 0.249411766156104 0.638200695752385 GO:0070840 dynein complex binding 4/1988 24/18639 0.166666666666667 1.56262575452716 0.249411766156104 0.638200695752385 GO:0008236 serine-type peptidase activity 24/1988 194/18639 0.123711340206186 1.15988715799954 0.250243022489337 0.638985327865855 GO:0015106 bicarbonate transmembrane transporter activity 5/1988 32/18639 0.15625 1.46496164486922 0.251565723582503 0.639680691698307 GO:0043425 bHLH transcription factor binding 5/1988 32/18639 0.15625 1.46496164486922 0.251565723582503 0.639680691698307 GO:0120013 lipid transfer activity 9/1988 65/18639 0.138461538461538 1.29818139606872 0.253788629328681 0.643988646921528 GO:0003689 DNA clamp loader activity 20/1988 160/18639 0.125 1.17196931589537 0.259012728427079 0.655878385081459 GO:0005319 lipid transporter activity 22/1988 178/18639 0.123595505617978 1.15880112133475 0.263327963638354 0.663508184991405 GO:0031406 carboxylic acid binding 23/1988 187/18639 0.122994652406417 1.1531676691163 0.26514757831537 0.663508184991405 GO:0061650 ubiquitin-like protein conjugating enzyme activity 6/1988 41/18639 0.146341463414634 1.37206163812141 0.269084926958227 0.663508184991405 GO:0140828 metal cation:monoatomic cation antiporter activity 6/1988 41/18639 0.146341463414634 1.37206163812141 0.269084926958227 0.663508184991405 GO:0004550 nucleoside diphosphate kinase activity 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:0005092 GDP-dissociation inhibitor activity 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:0008429 phosphatidylethanolamine binding 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:0017110 nucleoside diphosphate phosphatase activity 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:0019198 transmembrane receptor protein phosphatase activity 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:0045236 CXCR chemokine receptor binding 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:0070492 oligosaccharide binding 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:1990226 histone methyltransferase binding 3/1988 17/18639 0.176470588235294 1.65454491655817 0.269652341191088 0.663508184991405 GO:0019239 deaminase activity 5/1988 33/18639 0.151515151515152 1.42056886775197 0.272678409312363 0.664672004949279 GO:0005251 delayed rectifier potassium channel activity 4/1988 25/18639 0.16 1.50012072434608 0.273945276259883 0.664672004949279 GO:0015271 outward rectifier potassium channel activity 4/1988 25/18639 0.16 1.50012072434608 0.273945276259883 0.664672004949279 GO:0015645 fatty acid ligase activity 4/1988 25/18639 0.16 1.50012072434608 0.273945276259883 0.664672004949279 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 4/1988 25/18639 0.16 1.50012072434608 0.273945276259883 0.664672004949279 GO:0047617 fatty acyl-CoA hydrolase activity 4/1988 25/18639 0.16 1.50012072434608 0.273945276259883 0.664672004949279 GO:0120515 fatty acid-CoA ligase activity 4/1988 25/18639 0.16 1.50012072434608 0.273945276259883 0.664672004949279 GO:0032813 tumor necrosis factor receptor superfamily binding 7/1988 50/18639 0.14 1.31260563380282 0.281615987930681 0.672259127332887 GO:0048020 CCR chemokine receptor binding 7/1988 50/18639 0.14 1.31260563380282 0.281615987930681 0.672259127332887 GO:0004527 exonuclease activity 11/1988 84/18639 0.130952380952381 1.22777737855706 0.281625628647982 0.672259127332887 GO:0043177 organic acid binding 23/1988 189/18639 0.121693121693122 1.14096483663888 0.282455331781845 0.672259127332887 GO:0017171 serine hydrolase activity 24/1988 198/18639 0.121212121212121 1.13645509420157 0.28371897035425 0.672259127332887 GO:0017022 myosin binding 10/1988 76/18639 0.131578947368421 1.23365191146881 0.289692931279887 0.672259127332887 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0004090 carbonyl reductase (NADPH) activity 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0005381 iron ion transmembrane transporter activity 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0005522 profilin binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0005528 FK506 binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0032356 oxidized DNA binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0035256 G protein-coupled glutamate receptor binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0043121 neurotrophin binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0043208 glycosphingolipid binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0043422 protein kinase B binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0071723 lipopeptide binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0140135 mechanosensitive monoatomic cation channel activity 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:1905394 retromer complex binding 2/1988 10/18639 0.2 1.8751509054326 0.289766865229693 0.672259127332887 GO:0004879 nuclear receptor activity 8/1988 59/18639 0.135593220338983 1.27128874944583 0.290983406254265 0.672519523373235 GO:0031593 polyubiquitin modification-dependent protein binding 8/1988 59/18639 0.135593220338983 1.27128874944583 0.290983406254265 0.672519523373235 GO:0016831 carboxy-lyase activity 5/1988 34/18639 0.147058823529412 1.37878743046514 0.29414266402309 0.677250973119327 GO:0030332 cyclin binding 5/1988 34/18639 0.147058823529412 1.37878743046514 0.29414266402309 0.677250973119327 GO:0008198 ferrous iron binding 4/1988 26/18639 0.153846153846154 1.44242377340969 0.29885274284331 0.6780535356704 GO:0016289 acyl-CoA hydrolase activity 4/1988 26/18639 0.153846153846154 1.44242377340969 0.29885274284331 0.6780535356704 GO:0043548 phosphatidylinositol 3-kinase binding 4/1988 26/18639 0.153846153846154 1.44242377340969 0.29885274284331 0.6780535356704 GO:0016830 carbon-carbon lyase activity 7/1988 51/18639 0.137254901960784 1.28686826843413 0.29908730531954 0.6780535356704 GO:0015172 acidic amino acid transmembrane transporter activity 3/1988 18/18639 0.166666666666667 1.56262575452716 0.300058173831154 0.6780535356704 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/1988 18/18639 0.166666666666667 1.56262575452716 0.300058173831154 0.6780535356704 GO:0017128 phospholipid scramblase activity 3/1988 18/18639 0.166666666666667 1.56262575452716 0.300058173831154 0.6780535356704 GO:0070628 proteasome binding 3/1988 18/18639 0.166666666666667 1.56262575452716 0.300058173831154 0.6780535356704 GO:0098641 cadherin binding involved in cell-cell adhesion 3/1988 18/18639 0.166666666666667 1.56262575452716 0.300058173831154 0.6780535356704 GO:1990381 ubiquitin-specific protease binding 3/1988 18/18639 0.166666666666667 1.56262575452716 0.300058173831154 0.6780535356704 GO:0004714 transmembrane receptor protein tyrosine kinase activity 8/1988 60/18639 0.133333333333333 1.25010060362173 0.307214813563326 0.690876517531296 GO:0098531 ligand-modulated transcription factor activity 8/1988 60/18639 0.133333333333333 1.25010060362173 0.307214813563326 0.690876517531296 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1988 43/18639 0.13953488372093 1.30824481774367 0.307434378080429 0.690876517531296 GO:0140097 catalytic activity, acting on DNA 39/1988 336/18639 0.116071428571429 1.08825722190285 0.311267944452344 0.698203234517411 GO:0070851 growth factor receptor binding 17/1988 139/18639 0.122302158273381 1.14667501411346 0.312185608269102 0.698974394984864 GO:0016229 steroid dehydrogenase activity 5/1988 35/18639 0.142857142857143 1.33939350388043 0.315876034302152 0.701149321216349 GO:0061631 ubiquitin conjugating enzyme activity 5/1988 35/18639 0.142857142857143 1.33939350388043 0.315876034302152 0.701149321216349 GO:0031267 small GTPase binding 33/1988 283/18639 0.11660777385159 1.09328586359144 0.319561062986942 0.701149321216349 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 27/1988 229/18639 0.117903930131004 1.10543830669607 0.319566560984358 0.701149321216349 GO:0008081 phosphoric diester hydrolase activity 11/1988 87/18639 0.126436781609195 1.18544022757233 0.322118121727915 0.701149321216349 GO:0001671 ATPase activator activity 4/1988 27/18639 0.148148148148148 1.38900067069081 0.324007771953893 0.701149321216349 GO:0004683 calcium/calmodulin-dependent protein kinase activity 4/1988 27/18639 0.148148148148148 1.38900067069081 0.324007771953893 0.701149321216349 GO:0005044 scavenger receptor activity 4/1988 27/18639 0.148148148148148 1.38900067069081 0.324007771953893 0.701149321216349 GO:0016407 acetyltransferase activity 12/1988 96/18639 0.125 1.17196931589537 0.325199086606266 0.701149321216349 GO:0004252 serine-type endopeptidase activity 21/1988 176/18639 0.119318181818182 1.11869798335467 0.326460147404464 0.701149321216349 GO:0008028 monocarboxylic acid transmembrane transporter activity 9/1988 70/18639 0.128571428571429 1.20545415349238 0.328806201510061 0.701149321216349 GO:0005346 purine ribonucleotide transmembrane transporter activity 3/1988 19/18639 0.157894736842105 1.48038229376258 0.330618313500085 0.701149321216349 GO:0016918 retinal binding 3/1988 19/18639 0.157894736842105 1.48038229376258 0.330618313500085 0.701149321216349 GO:0022840 leak channel activity 3/1988 19/18639 0.157894736842105 1.48038229376258 0.330618313500085 0.701149321216349 GO:0022842 narrow pore channel activity 3/1988 19/18639 0.157894736842105 1.48038229376258 0.330618313500085 0.701149321216349 GO:0043395 heparan sulfate proteoglycan binding 3/1988 19/18639 0.157894736842105 1.48038229376258 0.330618313500085 0.701149321216349 GO:0097001 ceramide binding 3/1988 19/18639 0.157894736842105 1.48038229376258 0.330618313500085 0.701149321216349 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0000099 sulfur amino acid transmembrane transporter activity 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0004016 adenylate cyclase activity 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0005114 type II transforming growth factor beta receptor binding 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0008199 ferric iron binding 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0008432 JUN kinase binding 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0008526 phosphatidylinositol transfer activity 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0010854 adenylate cyclase regulator activity 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0042608 T cell receptor binding 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0050998 nitric-oxide synthase binding 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0070697 activin receptor binding 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1988 11/18639 0.181818181818182 1.70468264130236 0.331002347864861 0.701149321216349 GO:0005544 calcium-dependent phospholipid binding 7/1988 53/18639 0.132075471698113 1.23830720170077 0.334644523890604 0.70763373281034 GO:0003712 transcription coregulator activity 56/1988 495/18639 0.113131313131313 1.0606914212548 0.339288100522666 0.71620954321769 GO:0015179 L-amino acid transmembrane transporter activity 8/1988 62/18639 0.129032258064516 1.20977477769845 0.340200245078364 0.716892557967903 GO:0017124 SH3 domain binding 14/1988 115/18639 0.121739130434783 1.1413962033068 0.341798519523451 0.719016574748813 GO:0008170 N-methyltransferase activity 12/1988 98/18639 0.122448979591837 1.14805157475465 0.351592755318859 0.738344786169604 GO:0050661 NADP binding 7/1988 54/18639 0.12962962962963 1.21537558685446 0.352644587625827 0.739279015022818 GO:0022829 wide pore channel activity 5/1988 37/18639 0.135135135135135 1.26699385502202 0.359831806686106 0.752754784950519 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 3/1988 20/18639 0.15 1.40636317907445 0.36113259461609 0.752754784950519 GO:0140939 histone H4 methyltransferase activity 3/1988 20/18639 0.15 1.40636317907445 0.36113259461609 0.752754784950519 GO:0005125 cytokine activity 27/1988 234/18639 0.115384615384615 1.08181783005727 0.362124434235427 0.752754784950519 GO:0015101 organic cation transmembrane transporter activity 10/1988 81/18639 0.123456790123457 1.15750055890901 0.36216281115025 0.752754784950519 GO:0030246 carbohydrate binding 32/1988 280/18639 0.114285714285714 1.07151480310434 0.366460438476545 0.752941830808026 GO:0098632 cell-cell adhesion mediator activity 7/1988 55/18639 0.127272727272727 1.19327784891165 0.370736177108857 0.752941830808026 GO:0000340 RNA 7-methylguanosine cap binding 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0005049 nuclear export signal receptor activity 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0005078 MAP-kinase scaffold activity 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0005095 GTPase inhibitor activity 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0005527 macrolide binding 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0010853 cyclase activator activity 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0015368 calcium:monoatomic cation antiporter activity 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0016423 tRNA (guanine) methyltransferase activity 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0035497 cAMP response element binding 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0042301 phosphate ion binding 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0070410 co-SMAD binding 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/1988 12/18639 0.166666666666667 1.56262575452716 0.371525484659789 0.752941830808026 GO:0042578 phosphoric ester hydrolase activity 41/1988 363/18639 0.112947658402204 1.05896951959692 0.372328616888668 0.753316038821258 GO:0016417 S-acyltransferase activity 4/1988 29/18639 0.137931034482759 1.293207520988 0.374588542290183 0.755378881638151 GO:0035250 UDP-galactosyltransferase activity 4/1988 29/18639 0.137931034482759 1.293207520988 0.374588542290183 0.755378881638151 GO:0008194 UDP-glycosyltransferase activity 17/1988 145/18639 0.117241379310345 1.0992263928398 0.377741282473908 0.759393667881914 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 11/1988 91/18639 0.120879120879121 1.1333329648219 0.377826406187553 0.759393667881914 GO:0005109 frizzled binding 5/1988 38/18639 0.131578947368421 1.23365191146881 0.381902594538107 0.763805189076215 GO:0005501 retinoid binding 5/1988 38/18639 0.131578947368421 1.23365191146881 0.381902594538107 0.763805189076215 GO:0019840 isoprenoid binding 5/1988 38/18639 0.131578947368421 1.23365191146881 0.381902594538107 0.763805189076215 GO:0004386 helicase activity 18/1988 155/18639 0.116129032258065 1.0887972999286 0.388069732345216 0.773425608691379 GO:0003684 damaged DNA binding 9/1988 74/18639 0.121621621621622 1.14029446951982 0.391397030659043 0.773425608691379 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1988 21/18639 0.142857142857143 1.33939350388043 0.391422713555743 0.773425608691379 GO:0001846 opsonin binding 3/1988 21/18639 0.142857142857143 1.33939350388043 0.391422713555743 0.773425608691379 GO:0009975 cyclase activity 3/1988 21/18639 0.142857142857143 1.33939350388043 0.391422713555743 0.773425608691379 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/1988 21/18639 0.142857142857143 1.33939350388043 0.391422713555743 0.773425608691379 GO:1904047 S-adenosyl-L-methionine binding 3/1988 21/18639 0.142857142857143 1.33939350388043 0.391422713555743 0.773425608691379 GO:0008094 ATP-dependent activity, acting on DNA 24/1988 210/18639 0.114285714285714 1.07151480310434 0.39179277550294 0.773425608691379 GO:0035402 histone H3T11 kinase activity 28/1988 247/18639 0.11336032388664 1.06283856988082 0.395644617267758 0.779765604906358 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/1988 30/18639 0.133333333333333 1.25010060362173 0.399797366046217 0.785408373942407 GO:0031624 ubiquitin conjugating enzyme binding 4/1988 30/18639 0.133333333333333 1.25010060362173 0.399797366046217 0.785408373942407 GO:0035591 signaling adaptor activity 15/1988 129/18639 0.116279069767442 1.09020401478639 0.402297121415981 0.789046527994629 GO:0140693 molecular condensate scaffold activity 6/1988 48/18639 0.125 1.17196931589537 0.406050334412783 0.789623659478157 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0005542 folic acid binding 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0019855 calcium channel inhibitor activity 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0030955 potassium ion binding 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0031432 titin binding 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0035325 Toll-like receptor binding 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0039706 co-receptor binding 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0140852 histone ubiquitin ligase activity 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:1901338 catecholamine binding 2/1988 13/18639 0.153846153846154 1.44242377340969 0.411019211912276 0.789623659478157 GO:0016881 acid-amino acid ligase activity 3/1988 22/18639 0.136363636363636 1.27851198097677 0.421331874794125 0.807974985205603 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 8/1988 67/18639 0.119402985074627 1.11949307787021 0.42416058011062 0.807974985205603 GO:0042054 histone methyltransferase activity 8/1988 67/18639 0.119402985074627 1.11949307787021 0.42416058011062 0.807974985205603 GO:0005310 dicarboxylic acid transmembrane transporter activity 4/1988 31/18639 0.129032258064516 1.20977477769845 0.424820902742563 0.807974985205603 GO:0072349 modified amino acid transmembrane transporter activity 4/1988 31/18639 0.129032258064516 1.20977477769845 0.424820902742563 0.807974985205603 GO:0008408 3'-5' exonuclease activity 7/1988 58/18639 0.120689655172414 1.1315565808645 0.425157522098195 0.807974985205603 GO:0030331 nuclear estrogen receptor binding 5/1988 40/18639 0.125 1.17196931589537 0.42587844047783 0.807974985205603 GO:0050997 quaternary ammonium group binding 5/1988 40/18639 0.125 1.17196931589537 0.42587844047783 0.807974985205603 GO:0016247 channel regulator activity 19/1988 168/18639 0.113095238095238 1.060353190572 0.429505854508127 0.810657546349968 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 27/1988 243/18639 0.111111111111111 1.04175050301811 0.44113687600447 0.810657546349968 GO:0045309 protein phosphorylated amino acid binding 7/1988 59/18639 0.11864406779661 1.1123776557651 0.443219422307954 0.810657546349968 GO:0005006 epidermal growth factor receptor activity 6/1988 50/18639 0.12 1.12509054325956 0.445477904651917 0.810657546349968 GO:0015605 organophosphate ester transmembrane transporter activity 6/1988 50/18639 0.12 1.12509054325956 0.445477904651917 0.810657546349968 GO:0046943 carboxylic acid transmembrane transporter activity 21/1988 188/18639 0.111702127659574 1.04729172909799 0.445647547622836 0.810657546349968 GO:0015175 neutral L-amino acid transmembrane transporter activity 5/1988 41/18639 0.121951219512195 1.14338469843451 0.447655317355553 0.810657546349968 GO:0016877 ligase activity, forming carbon-sulfur bonds 5/1988 41/18639 0.121951219512195 1.14338469843451 0.447655317355553 0.810657546349968 GO:0017080 sodium channel regulator activity 5/1988 41/18639 0.121951219512195 1.14338469843451 0.447655317355553 0.810657546349968 GO:0004705 JUN kinase activity 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:0005347 ATP transmembrane transporter activity 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:0005545 1-phosphatidylinositol binding 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:0008174 mRNA methyltransferase activity 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:0008331 high voltage-gated calcium channel activity 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:0008494 translation activator activity 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:0070742 C2H2 zinc finger domain binding 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:0071933 Arp2/3 complex binding 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:1990825 sequence-specific mRNA binding 2/1988 14/18639 0.142857142857143 1.33939350388043 0.449242139894925 0.810657546349968 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/1988 32/18639 0.125 1.17196931589537 0.449571642622571 0.810657546349968 GO:0070717 poly-purine tract binding 4/1988 32/18639 0.125 1.17196931589537 0.449571642622571 0.810657546349968 GO:0140142 nucleocytoplasmic carrier activity 4/1988 32/18639 0.125 1.17196931589537 0.449571642622571 0.810657546349968 GO:0005516 calmodulin binding 23/1988 207/18639 0.111111111111111 1.04175050301811 0.45053252330369 0.810657546349968 GO:0000295 adenine nucleotide transmembrane transporter activity 3/1988 23/18639 0.130434782608696 1.222924503543 0.450724047898732 0.810657546349968 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1988 23/18639 0.130434782608696 1.222924503543 0.450724047898732 0.810657546349968 GO:0005212 structural constituent of eye lens 3/1988 23/18639 0.130434782608696 1.222924503543 0.450724047898732 0.810657546349968 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/1988 23/18639 0.130434782608696 1.222924503543 0.450724047898732 0.810657546349968 GO:0141108 transporter regulator activity 19/1988 170/18639 0.111764705882353 1.04787844715351 0.450724228317757 0.810657546349968 GO:0019199 transmembrane receptor protein kinase activity 9/1988 78/18639 0.115384615384615 1.08181783005727 0.454426592462787 0.810657546349968 GO:0005342 organic acid transmembrane transporter activity 21/1988 189/18639 0.111111111111111 1.04175050301811 0.455720471825071 0.810657546349968 GO:0004676 3-phosphoinositide-dependent protein kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0004711 ribosomal protein S6 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0035175 histone H3S10 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0035979 histone H2AXS139 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0044022 histone H3S28 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0044023 histone H4S1 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0044024 histone H2AS1 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0044025 histone H2BS14 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0072354 histone H3T3 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0072371 histone H2AS121 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0072518 Rho-dependent protein serine/threonine kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0140823 histone H2BS36 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0140855 histone H3S57 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0140995 histone H2A kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0140997 histone H4 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0140998 histone H2B kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:1990244 histone H2AT120 kinase activity 27/1988 245/18639 0.110204081632653 1.03324641727919 0.458853228610122 0.810657546349968 GO:0008013 beta-catenin binding 12/1988 106/18639 0.113207547169811 1.06140617288637 0.459239496700721 0.810657546349968 GO:0016791 phosphatase activity 30/1988 273/18639 0.10989010989011 1.03030269529264 0.459950953333236 0.810738438726311 GO:0005021 vascular endothelial growth factor receptor activity 6/1988 51/18639 0.117647058823529 1.10302994437212 0.464996651229566 0.817266841554996 GO:0016597 amino acid binding 6/1988 51/18639 0.117647058823529 1.10302994437212 0.464996651229566 0.817266841554996 GO:0004677 DNA-dependent protein kinase activity 27/1988 246/18639 0.109756097560976 1.02904622859106 0.467706328691418 0.819663753016039 GO:0140857 histone H3T45 kinase activity 27/1988 246/18639 0.109756097560976 1.02904622859106 0.467706328691418 0.819663753016039 GO:0031492 nucleosomal DNA binding 5/1988 42/18639 0.119047619047619 1.11616125323369 0.469213484293378 0.819945514877094 GO:0035198 miRNA binding 5/1988 42/18639 0.119047619047619 1.11616125323369 0.469213484293378 0.819945514877094 GO:0140311 protein sequestering activity 4/1988 33/18639 0.121212121212121 1.13645509420157 0.473970709286048 0.827072097292847 GO:0035403 histone H3T6 kinase activity 27/1988 247/18639 0.109311740890688 1.02488004952794 0.476550266002503 0.830383725309083 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/1988 24/18639 0.125 1.17196931589537 0.479482945290535 0.830740010474924 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/1988 24/18639 0.125 1.17196931589537 0.479482945290535 0.830740010474924 GO:0015295 solute:proton symporter activity 3/1988 24/18639 0.125 1.17196931589537 0.479482945290535 0.830740010474924 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/1988 24/18639 0.125 1.17196931589537 0.479482945290535 0.830740010474924 GO:0004679 AMP-activated protein kinase activity 27/1988 248/18639 0.108870967741935 1.02074746868307 0.485380767579949 0.832584422984526 GO:0010181 FMN binding 2/1988 15/18639 0.133333333333333 1.25010060362173 0.486016030165844 0.832584422984526 GO:0015929 hexosaminidase activity 2/1988 15/18639 0.133333333333333 1.25010060362173 0.486016030165844 0.832584422984526 GO:0031005 filamin binding 2/1988 15/18639 0.133333333333333 1.25010060362173 0.486016030165844 0.832584422984526 GO:0048531 beta-1,3-galactosyltransferase activity 2/1988 15/18639 0.133333333333333 1.25010060362173 0.486016030165844 0.832584422984526 GO:0051371 muscle alpha-actinin binding 2/1988 15/18639 0.133333333333333 1.25010060362173 0.486016030165844 0.832584422984526 GO:0061578 K63-linked deubiquitinase activity 2/1988 15/18639 0.133333333333333 1.25010060362173 0.486016030165844 0.832584422984526 GO:0120283 protein serine/threonine kinase binding 2/1988 15/18639 0.133333333333333 1.25010060362173 0.486016030165844 0.832584422984526 GO:0008200 ion channel inhibitor activity 5/1988 43/18639 0.116279069767442 1.09020401478639 0.490500208795081 0.839086031337653 GO:0004620 phospholipase activity 12/1988 109/18639 0.110091743119266 1.03219315895372 0.499328385386808 0.852990145022625 GO:0005003 ephrin receptor activity 6/1988 53/18639 0.113207547169811 1.06140617288637 0.503438259805265 0.853795808930386 GO:0005005 transmembrane-ephrin receptor activity 6/1988 53/18639 0.113207547169811 1.06140617288637 0.503438259805265 0.853795808930386 GO:0034212 protein N-acetyltransferase activity 6/1988 53/18639 0.113207547169811 1.06140617288637 0.503438259805265 0.853795808930386 GO:0000030 mannosyltransferase activity 3/1988 25/18639 0.12 1.12509054325956 0.507510809249261 0.853795808930386 GO:0003707 nuclear steroid receptor activity 3/1988 25/18639 0.12 1.12509054325956 0.507510809249261 0.853795808930386 GO:0015662 P-type ion transporter activity 3/1988 25/18639 0.12 1.12509054325956 0.507510809249261 0.853795808930386 GO:0017025 TBP-class protein binding 3/1988 25/18639 0.12 1.12509054325956 0.507510809249261 0.853795808930386 GO:0017056 structural constituent of nuclear pore 3/1988 25/18639 0.12 1.12509054325956 0.507510809249261 0.853795808930386 GO:0019706 protein-cysteine S-palmitoyltransferase activity 3/1988 25/18639 0.12 1.12509054325956 0.507510809249261 0.853795808930386 GO:0019707 protein-cysteine S-acyltransferase activity 3/1988 25/18639 0.12 1.12509054325956 0.507510809249261 0.853795808930386 GO:0140358 P-type transmembrane transporter activity 3/1988 25/18639 0.12 1.12509054325956 0.507510809249261 0.853795808930386 GO:0016248 channel inhibitor activity 5/1988 44/18639 0.113636363636364 1.06542665081397 0.511467446343152 0.858081748823634 GO:0030547 signaling receptor inhibitor activity 5/1988 44/18639 0.113636363636364 1.06542665081397 0.511467446343152 0.858081748823634 GO:0004707 MAP kinase activity 2/1988 16/18639 0.125 1.17196931589537 0.521215081293856 0.861757163173231 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1988 16/18639 0.125 1.17196931589537 0.521215081293856 0.861757163173231 GO:0005521 lamin binding 2/1988 16/18639 0.125 1.17196931589537 0.521215081293856 0.861757163173231 GO:0022858 alanine transmembrane transporter activity 2/1988 16/18639 0.125 1.17196931589537 0.521215081293856 0.861757163173231 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1988 16/18639 0.125 1.17196931589537 0.521215081293856 0.861757163173231 GO:0043023 ribosomal large subunit binding 2/1988 16/18639 0.125 1.17196931589537 0.521215081293856 0.861757163173231 GO:0070411 I-SMAD binding 2/1988 16/18639 0.125 1.17196931589537 0.521215081293856 0.861757163173231 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 2/1988 16/18639 0.125 1.17196931589537 0.521215081293856 0.861757163173231 GO:0005154 epidermal growth factor receptor binding 4/1988 35/18639 0.114285714285714 1.07151480310434 0.521440910721405 0.861757163173231 GO:0005343 organic acid:sodium symporter activity 4/1988 35/18639 0.114285714285714 1.07151480310434 0.521440910721405 0.861757163173231 GO:0043015 gamma-tubulin binding 4/1988 35/18639 0.114285714285714 1.07151480310434 0.521440910721405 0.861757163173231 GO:0016298 lipase activity 14/1988 130/18639 0.107692307692308 1.00969664138678 0.526789929370139 0.86941752570844 GO:0004536 DNA nuclease activity 7/1988 64/18639 0.109375 1.02547315140845 0.531408021282677 0.870718692452693 GO:0015171 amino acid transmembrane transporter activity 11/1988 102/18639 0.107843137254902 1.01111078234111 0.531892977180538 0.870718692452693 GO:0141110 transporter inhibitor activity 5/1988 45/18639 0.111111111111111 1.04175050301811 0.532071830595015 0.870718692452693 GO:0004713 protein tyrosine kinase activity 15/1988 140/18639 0.107142857142857 1.00454512791032 0.533166730946868 0.870718692452693 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/1988 26/18639 0.115384615384615 1.08181783005727 0.534727078780471 0.870718692452693 GO:0008143 poly(A) binding 3/1988 26/18639 0.115384615384615 1.08181783005727 0.534727078780471 0.870718692452693 GO:0015216 purine nucleotide transmembrane transporter activity 3/1988 26/18639 0.115384615384615 1.08181783005727 0.534727078780471 0.870718692452693 GO:0050681 nuclear androgen receptor binding 3/1988 26/18639 0.115384615384615 1.08181783005727 0.534727078780471 0.870718692452693 GO:0097602 cullin family protein binding 3/1988 26/18639 0.115384615384615 1.08181783005727 0.534727078780471 0.870718692452693 GO:0120014 phospholipid transfer activity 3/1988 26/18639 0.115384615384615 1.08181783005727 0.534727078780471 0.870718692452693 GO:0051219 phosphoprotein binding 10/1988 93/18639 0.10752688172043 1.00814564808204 0.538773476954399 0.876136308318369 GO:0016409 palmitoyltransferase activity 4/1988 36/18639 0.111111111111111 1.04175050301811 0.544396244561493 0.883532779525261 GO:0099106 ion channel regulator activity 17/1988 160/18639 0.10625 0.996173918511066 0.544772674403506 0.883532779525261 GO:0160215 deacylase activity 7/1988 65/18639 0.107692307692308 1.00969664138678 0.548416324602889 0.888259419370106 GO:0042562 hormone binding 10/1988 94/18639 0.106382978723404 0.99742069437904 0.552886554526546 0.892594132111765 GO:0016805 dipeptidase activity 2/1988 17/18639 0.117647058823529 1.10302994437212 0.554756779974225 0.892594132111765 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/1988 17/18639 0.117647058823529 1.10302994437212 0.554756779974225 0.892594132111765 GO:0030548 acetylcholine receptor regulator activity 2/1988 17/18639 0.117647058823529 1.10302994437212 0.554756779974225 0.892594132111765 GO:0070403 NAD+ binding 2/1988 17/18639 0.117647058823529 1.10302994437212 0.554756779974225 0.892594132111765 GO:0170055 lipid transmembrane transporter activity 6/1988 56/18639 0.107142857142857 1.00454512791032 0.559080733199927 0.898364555458457 GO:0005104 fibroblast growth factor receptor binding 3/1988 27/18639 0.111111111111111 1.04175050301811 0.561066992133794 0.899183679498632 GO:0008266 poly(U) RNA binding 3/1988 27/18639 0.111111111111111 1.04175050301811 0.561066992133794 0.899183679498632 GO:0001784 phosphotyrosine residue binding 5/1988 47/18639 0.106382978723404 0.99742069437904 0.572041579115168 0.914365673703772 GO:0043495 protein-membrane adaptor activity 5/1988 47/18639 0.106382978723404 0.99742069437904 0.572041579115168 0.914365673703772 GO:0015291 secondary active transmembrane transporter activity 30/1988 287/18639 0.104529616724739 0.98004402722958 0.575512980930512 0.918708795246872 GO:0015932 nucleobase-containing compound transmembrane transporter activity 6/1988 57/18639 0.105263157894737 0.98692152917505 0.576968864920425 0.919525895487629 GO:0141003 histone H2AX kinase activity 37/1988 354/18639 0.104519774011299 0.979951744364492 0.578244916565323 0.919525895487629 GO:0015297 antiporter activity 14/1988 135/18639 0.103703703703704 0.972300469483568 0.585843856696292 0.919525895487629 GO:0046875 ephrin receptor binding 3/1988 28/18639 0.107142857142857 1.00454512791032 0.586480168496987 0.919525895487629 GO:0008308 voltage-gated monoatomic anion channel activity 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0008525 phosphatidylcholine transporter activity 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0017075 syntaxin-1 binding 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0022851 GABA-gated chloride ion channel activity 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0030228 lipoprotein particle receptor activity 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0031690 adrenergic receptor binding 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0034185 apolipoprotein binding 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0050811 GABA receptor binding 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0070064 proline-rich region binding 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0099602 neurotransmitter receptor regulator activity 2/1988 18/18639 0.111111111111111 1.04175050301811 0.586594105742108 0.919525895487629 GO:0005548 phospholipid transporter activity 7/1988 68/18639 0.102941176470588 0.965151201325601 0.597745482432465 0.933107386437535 GO:0019888 protein phosphatase regulator activity 11/1988 107/18639 0.102803738317757 0.963862614941988 0.597969616722996 0.933107386437535 GO:0140996 histone H3 kinase activity 37/1988 357/18639 0.103641456582633 0.971716855756387 0.599692711325754 0.933107386437535 GO:0015293 symporter activity 15/1988 146/18639 0.102739726027397 0.963262451420854 0.601010494688369 0.933107386437535 GO:0019208 phosphatase regulator activity 12/1988 117/18639 0.102564102564103 0.961615848939793 0.601639694506573 0.933107386437535 GO:0004197 cysteine-type endopeptidase activity 9/1988 88/18639 0.102272727272727 0.958883985732577 0.60429089907613 0.933107386437535 GO:0140375 immune receptor activity 16/1988 156/18639 0.102564102564103 0.961615848939793 0.60459212341734 0.933107386437535 GO:0005004 GPI-linked ephrin receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0005008 hepatocyte growth factor receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0005009 insulin receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0005011 macrophage colony-stimulating factor receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0005020 stem cell factor receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0008288 boss receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0036332 placental growth factor receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0038062 protein tyrosine kinase collagen receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0060175 brain-derived neurotrophic factor receptor activity 5/1988 49/18639 0.102040816326531 0.956709645628875 0.610152933456125 0.933107386437535 GO:0005416 amino acid:monoatomic cation symporter activity 3/1988 29/18639 0.103448275862069 0.969905640740998 0.610929202290079 0.933107386437535 GO:0070063 RNA polymerase binding 6/1988 59/18639 0.101694915254237 0.953466562084371 0.611610026551108 0.933107386437535 GO:0008080 N-acetyltransferase activity 7/1988 69/18639 0.101449275362319 0.951163502755665 0.613559359194625 0.933107386437535 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/1988 19/18639 0.105263157894737 0.98692152917505 0.616708904829406 0.933107386437535 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1988 19/18639 0.105263157894737 0.98692152917505 0.616708904829406 0.933107386437535 GO:0004890 GABA-A receptor activity 2/1988 19/18639 0.105263157894737 0.98692152917505 0.616708904829406 0.933107386437535 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1988 19/18639 0.105263157894737 0.98692152917505 0.616708904829406 0.933107386437535 GO:0015245 fatty acid transmembrane transporter activity 2/1988 19/18639 0.105263157894737 0.98692152917505 0.616708904829406 0.933107386437535 GO:0030506 ankyrin binding 2/1988 19/18639 0.105263157894737 0.98692152917505 0.616708904829406 0.933107386437535 GO:0031420 alkali metal ion binding 2/1988 19/18639 0.105263157894737 0.98692152917505 0.616708904829406 0.933107386437535 GO:0034987 immunoglobulin receptor binding 2/1988 19/18639 0.105263157894737 0.98692152917505 0.616708904829406 0.933107386437535 GO:0003727 single-stranded RNA binding 9/1988 89/18639 0.101123595505618 0.948110008364795 0.618170527176198 0.93415843933078 GO:0035173 histone kinase activity 37/1988 360/18639 0.102777777777778 0.96361921529175 0.620722884952071 0.936853127474129 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1988 60/18639 0.1 0.937575452716298 0.628324218927784 0.943837599894447 GO:0005007 fibroblast growth factor receptor activity 5/1988 50/18639 0.1 0.937575452716298 0.628450158878815 0.943837599894447 GO:0005017 platelet-derived growth factor receptor activity 5/1988 50/18639 0.1 0.937575452716298 0.628450158878815 0.943837599894447 GO:0005019 platelet-derived growth factor beta-receptor activity 5/1988 50/18639 0.1 0.937575452716298 0.628450158878815 0.943837599894447 GO:0001965 G-protein alpha-subunit binding 3/1988 30/18639 0.1 0.937575452716298 0.634388295206064 0.946239157399781 GO:0008187 poly-pyrimidine tract binding 3/1988 30/18639 0.1 0.937575452716298 0.634388295206064 0.946239157399781 GO:0031210 phosphatidylcholine binding 3/1988 30/18639 0.1 0.937575452716298 0.634388295206064 0.946239157399781 GO:0033612 receptor serine/threonine kinase binding 3/1988 30/18639 0.1 0.937575452716298 0.634388295206064 0.946239157399781 GO:0051721 protein phosphatase 2A binding 3/1988 30/18639 0.1 0.937575452716298 0.634388295206064 0.946239157399781 GO:0001972 retinoic acid binding 2/1988 20/18639 0.1 0.937575452716298 0.645106272630884 0.946239157399781 GO:0010851 cyclase regulator activity 2/1988 20/18639 0.1 0.937575452716298 0.645106272630884 0.946239157399781 GO:0031418 L-ascorbic acid binding 2/1988 20/18639 0.1 0.937575452716298 0.645106272630884 0.946239157399781 GO:0052745 inositol phosphate phosphatase activity 2/1988 20/18639 0.1 0.937575452716298 0.645106272630884 0.946239157399781 GO:0061608 nuclear import signal receptor activity 2/1988 20/18639 0.1 0.937575452716298 0.645106272630884 0.946239157399781 GO:0005010 insulin-like growth factor receptor activity 5/1988 51/18639 0.0980392156862745 0.919191620310096 0.646216844492864 0.946239157399781 GO:0005030 neurotrophin receptor activity 5/1988 51/18639 0.0980392156862745 0.919191620310096 0.646216844492864 0.946239157399781 GO:0005048 signal sequence binding 5/1988 51/18639 0.0980392156862745 0.919191620310096 0.646216844492864 0.946239157399781 GO:0030544 Hsp70 protein binding 5/1988 51/18639 0.0980392156862745 0.919191620310096 0.646216844492864 0.946239157399781 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/1988 41/18639 0.0975609756097561 0.914707758747608 0.64974140037454 0.946239157399781 GO:0001217 DNA-binding transcription repressor activity 28/1988 278/18639 0.100719424460432 0.944320599858142 0.655498826854215 0.946239157399781 GO:0005164 tumor necrosis factor receptor binding 3/1988 31/18639 0.0967741935483871 0.907331083273837 0.656841944398582 0.946239157399781 GO:0005085 guanyl-nucleotide exchange factor activity 23/1988 230/18639 0.1 0.937575452716298 0.660527309915348 0.946239157399781 GO:0005080 protein kinase C binding 5/1988 52/18639 0.0961538461538462 0.901514858381056 0.663438898695856 0.946239157399781 GO:0030159 signaling receptor complex adaptor activity 5/1988 52/18639 0.0961538461538462 0.901514858381056 0.663438898695856 0.946239157399781 GO:0004520 DNA endonuclease activity 4/1988 42/18639 0.0952380952380952 0.89292900258695 0.668744338909398 0.946239157399781 GO:0015125 bile acid transmembrane transporter activity 2/1988 21/18639 0.0952380952380952 0.89292900258695 0.67180980516511 0.946239157399781 GO:0061891 calcium ion sensor activity 2/1988 21/18639 0.0952380952380952 0.89292900258695 0.67180980516511 0.946239157399781 GO:0070182 DNA polymerase binding 2/1988 21/18639 0.0952380952380952 0.89292900258695 0.67180980516511 0.946239157399781 GO:0000182 rDNA binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0003796 lysozyme activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0004382 GDP phosphatase activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0004935 adrenergic receptor activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0005345 purine nucleobase transmembrane transporter activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0008140 cAMP response element binding protein binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0015187 glycine transmembrane transporter activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0015279 store-operated calcium channel activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0015643 toxic substance binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0016868 intramolecular phosphotransferase activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0031419 cobalamin binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0032052 bile acid binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0035374 chondroitin sulfate binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0050815 phosphoserine residue binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0051378 serotonin binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0070097 delta-catenin binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0070513 death domain binding 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0140999 histone H3K4 trimethyltransferase activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:1990757 ubiquitin ligase activator activity 1/1988 10/18639 0.1 0.937575452716298 0.676367673488652 0.946239157399781 GO:0005246 calcium channel regulator activity 5/1988 53/18639 0.0943396226415094 0.884505144071979 0.680105631913626 0.946239157399781 GO:0016251 RNA polymerase II general transcription initiation factor activity 5/1988 53/18639 0.0943396226415094 0.884505144071979 0.680105631913626 0.946239157399781 GO:0038064 collagen receptor activity 5/1988 53/18639 0.0943396226415094 0.884505144071979 0.680105631913626 0.946239157399781 GO:0051018 protein kinase A binding 5/1988 53/18639 0.0943396226415094 0.884505144071979 0.680105631913626 0.946239157399781 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1988 53/18639 0.0943396226415094 0.884505144071979 0.680105631913626 0.946239157399781 GO:0019903 protein phosphatase binding 14/1988 144/18639 0.0972222222222222 0.911531690140845 0.683260186000665 0.946239157399781 GO:0008375 acetylglucosaminyltransferase activity 4/1988 43/18639 0.0930232558139535 0.872163211829114 0.687025788151893 0.946239157399781 GO:0106310 protein serine kinase activity 36/1988 361/18639 0.0997229916897507 0.934978290797416 0.691814853563004 0.946239157399781 GO:0035401 histone H3Y41 kinase activity 11/1988 115/18639 0.0956521739130435 0.896811302598198 0.693574889486871 0.946239157399781 GO:0140801 histone H2AXY142 kinase activity 11/1988 115/18639 0.0956521739130435 0.896811302598198 0.693574889486871 0.946239157399781 GO:0008276 protein methyltransferase activity 9/1988 95/18639 0.0947368421052632 0.888229376257545 0.695756527097987 0.946239157399781 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/1988 54/18639 0.0925925925925926 0.868125419181757 0.696209526106068 0.946239157399781 GO:0140463 chromatin-protein adaptor activity 5/1988 54/18639 0.0925925925925926 0.868125419181757 0.696209526106068 0.946239157399781 GO:0031683 G-protein beta/gamma-subunit complex binding 2/1988 22/18639 0.0909090909090909 0.85234132065118 0.696857598202208 0.946239157399781 GO:0050321 tau-protein kinase activity 2/1988 22/18639 0.0909090909090909 0.85234132065118 0.696857598202208 0.946239157399781 GO:0140035 ubiquitin-like protein reader activity 2/1988 22/18639 0.0909090909090909 0.85234132065118 0.696857598202208 0.946239157399781 GO:0140784 metal ion sensor activity 2/1988 22/18639 0.0909090909090909 0.85234132065118 0.696857598202208 0.946239157399781 GO:0019956 chemokine binding 3/1988 33/18639 0.0909090909090909 0.85234132065118 0.698714998801588 0.946239157399781 GO:0030296 protein tyrosine kinase activator activity 3/1988 33/18639 0.0909090909090909 0.85234132065118 0.698714998801588 0.946239157399781 GO:0015294 solute:monoatomic cation symporter activity 11/1988 116/18639 0.0948275862068965 0.889080170679248 0.704493668574109 0.946239157399781 GO:0043014 alpha-tubulin binding 4/1988 44/18639 0.0909090909090909 0.85234132065118 0.704581622332767 0.946239157399781 GO:0003713 transcription coactivator activity 25/1988 256/18639 0.09765625 0.91560102804326 0.710186705287923 0.946239157399781 GO:0001851 complement component C3b binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0002162 dystroglycan binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0005225 volume-sensitive anion channel activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0008172 S-methyltransferase activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0015205 nucleobase transmembrane transporter activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0015217 ADP transmembrane transporter activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0019107 myristoyltransferase activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0019206 nucleoside kinase activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0019215 intermediate filament binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0031731 CCR6 chemokine receptor binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0032050 clathrin heavy chain binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0032404 mismatch repair complex binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0034056 estrogen response element binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0035252 UDP-xylosyltransferase activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0042285 xylosyltransferase activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0043522 leucine zipper domain binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0045294 alpha-catenin binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0050786 RAGE receptor binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0140031 phosphorylation-dependent protein binding 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0140537 transcription regulator activator activity 1/1988 11/18639 0.0909090909090909 0.85234132065118 0.710904206051031 0.946239157399781 GO:0008234 cysteine-type peptidase activity 18/1988 187/18639 0.0962566844919786 0.902479045395367 0.712753629076006 0.946239157399781 GO:0008376 acetylgalactosaminyltransferase activity 3/1988 34/18639 0.0882352941176471 0.827272458279086 0.718144084299699 0.946239157399781 GO:0003887 DNA-directed DNA polymerase activity 2/1988 23/18639 0.0869565217391304 0.815283002361998 0.720298888707302 0.946239157399781 GO:0005283 amino acid:sodium symporter activity 2/1988 23/18639 0.0869565217391304 0.815283002361998 0.720298888707302 0.946239157399781 GO:0016917 GABA receptor activity 2/1988 23/18639 0.0869565217391304 0.815283002361998 0.720298888707302 0.946239157399781 GO:0043274 phospholipase binding 2/1988 23/18639 0.0869565217391304 0.815283002361998 0.720298888707302 0.946239157399781 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/1988 23/18639 0.0869565217391304 0.815283002361998 0.720298888707302 0.946239157399781 GO:0004715 non-membrane spanning protein tyrosine kinase activity 4/1988 45/18639 0.0888888888888889 0.833400402414487 0.721411845916938 0.946239157399781 GO:0140303 intramembrane lipid transporter activity 4/1988 45/18639 0.0888888888888889 0.833400402414487 0.721411845916938 0.946239157399781 GO:0005249 voltage-gated potassium channel activity 9/1988 98/18639 0.0918367346938776 0.861038681065988 0.73058342257905 0.946239157399781 GO:0016500 protein-hormone receptor activity 6/1988 67/18639 0.0895522388059701 0.839619808402655 0.732844679112177 0.946239157399781 GO:0034061 DNA polymerase activity 3/1988 35/18639 0.0857142857142857 0.803636102328255 0.736585006822664 0.946239157399781 GO:0019902 phosphatase binding 18/1988 190/18639 0.0947368421052632 0.888229376257545 0.737429120559633 0.946239157399781 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0003720 telomerase activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0003995 acyl-CoA dehydrogenase activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0005025 transforming growth factor beta receptor activity, type I 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0005026 transforming growth factor beta receptor activity, type II 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0005436 sodium:phosphate symporter activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0015166 polyol transmembrane transporter activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0016361 activin receptor activity, type I 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0016362 activin receptor activity, type II 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0016801 hydrolase activity, acting on ether bonds 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0016803 ether hydrolase activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0017002 activin receptor activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0017166 vinculin binding 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0031543 peptidyl-proline dioxygenase activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0034452 dynactin binding 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0140900 chloride:bicarbonate antiporter activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:1990459 transferrin receptor binding 1/1988 12/18639 0.0833333333333333 0.781312877263581 0.741756817086598 0.946239157399781 GO:0004622 lysophospholipase activity 2/1988 24/18639 0.0833333333333333 0.781312877263581 0.742191247199735 0.946239157399781 GO:0015149 hexose transmembrane transporter activity 2/1988 24/18639 0.0833333333333333 0.781312877263581 0.742191247199735 0.946239157399781 GO:0019957 C-C chemokine binding 2/1988 24/18639 0.0833333333333333 0.781312877263581 0.742191247199735 0.946239157399781 GO:0055056 D-glucose transmembrane transporter activity 2/1988 24/18639 0.0833333333333333 0.781312877263581 0.742191247199735 0.946239157399781 GO:0060229 lipase activator activity 2/1988 24/18639 0.0833333333333333 0.781312877263581 0.742191247199735 0.946239157399781 GO:0140223 general transcription initiation factor activity 6/1988 68/18639 0.0882352941176471 0.827272458279086 0.745918794919891 0.946239157399781 GO:0061733 protein-lysine-acetyltransferase activity 4/1988 47/18639 0.0851063829787234 0.797936555503232 0.752913509295374 0.946239157399781 GO:0061749 forked DNA-dependent helicase activity 4/1988 47/18639 0.0851063829787234 0.797936555503232 0.752913509295374 0.946239157399781 GO:0140359 ABC-type transporter activity 4/1988 47/18639 0.0851063829787234 0.797936555503232 0.752913509295374 0.946239157399781 GO:0140938 histone H3 methyltransferase activity 4/1988 47/18639 0.0851063829787234 0.797936555503232 0.752913509295374 0.946239157399781 GO:1990518 single-stranded 3'-5' DNA helicase activity 4/1988 47/18639 0.0851063829787234 0.797936555503232 0.752913509295374 0.946239157399781 GO:0045505 dynein intermediate chain binding 3/1988 36/18639 0.0833333333333333 0.781312877263581 0.75405671248277 0.946239157399781 GO:0061980 regulatory RNA binding 5/1988 58/18639 0.0862068965517241 0.808254700617498 0.754944329955188 0.946239157399781 GO:0005537 D-mannose binding 2/1988 25/18639 0.08 0.750060362173038 0.762598241804124 0.946239157399781 GO:0008139 nuclear localization sequence binding 2/1988 25/18639 0.08 0.750060362173038 0.762598241804124 0.946239157399781 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1988 25/18639 0.08 0.750060362173038 0.762598241804124 0.946239157399781 GO:0042974 nuclear retinoic acid receptor binding 2/1988 25/18639 0.08 0.750060362173038 0.762598241804124 0.946239157399781 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 11/1988 122/18639 0.0901639344262295 0.845354916383547 0.764773212216569 0.946239157399781 GO:0009378 four-way junction helicase activity 4/1988 48/18639 0.0833333333333333 0.781312877263581 0.767601747718707 0.946239157399781 GO:0036121 double-stranded DNA helicase activity 4/1988 48/18639 0.0833333333333333 0.781312877263581 0.767601747718707 0.946239157399781 GO:0038187 pattern recognition receptor activity 4/1988 48/18639 0.0833333333333333 0.781312877263581 0.767601747718707 0.946239157399781 GO:0043138 3'-5' DNA helicase activity 4/1988 48/18639 0.0833333333333333 0.781312877263581 0.767601747718707 0.946239157399781 GO:0015459 potassium channel regulator activity 5/1988 59/18639 0.0847457627118644 0.794555468403642 0.768216024714825 0.946239157399781 GO:0002161 aminoacyl-tRNA editing activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0003964 RNA-directed DNA polymerase activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0004465 lipoprotein lipase activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0004993 G protein-coupled serotonin receptor activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0045159 myosin II binding 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0046974 histone H3K9 methyltransferase activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0046975 histone H3K36 methyltransferase activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0051011 microtubule minus-end binding 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0070123 transforming growth factor beta receptor activity, type III 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0070700 BMP receptor binding 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0071714 icosanoid transmembrane transporter activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0089720 caspase binding 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0097157 pre-mRNA intronic binding 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0140666 annealing activity 1/1988 13/18639 0.0769230769230769 0.721211886704844 0.769318284184458 0.946239157399781 GO:0019213 deacetylase activity 3/1988 37/18639 0.0810810810810811 0.760196313013215 0.770582214327424 0.946239157399781 GO:0003823 antigen binding 16/1988 174/18639 0.0919540229885057 0.862138347325331 0.770636392279876 0.946239157399781 GO:0016278 lysine N-methyltransferase activity 6/1988 70/18639 0.0857142857142857 0.803636102328255 0.770664404056308 0.946239157399781 GO:0005506 iron ion binding 14/1988 154/18639 0.0909090909090909 0.85234132065118 0.774239944941536 0.949671956635238 GO:0004529 DNA exonuclease activity 2/1988 26/18639 0.0769230769230769 0.721211886704844 0.781587505389428 0.952727431263461 GO:0015145 monosaccharide transmembrane transporter activity 2/1988 26/18639 0.0769230769230769 0.721211886704844 0.781587505389428 0.952727431263461 GO:0030247 polysaccharide binding 2/1988 26/18639 0.0769230769230769 0.721211886704844 0.781587505389428 0.952727431263461 GO:0030507 spectrin binding 2/1988 26/18639 0.0769230769230769 0.721211886704844 0.781587505389428 0.952727431263461 GO:0035254 glutamate receptor binding 4/1988 49/18639 0.0816326530612245 0.7653677165031 0.781597197875381 0.952727431263461 GO:0005267 potassium channel activity 11/1988 124/18639 0.0887096774193548 0.831720159667684 0.782839963037714 0.952727431263461 GO:0042162 telomeric DNA binding 3/1988 38/18639 0.0789473684210526 0.740191146881288 0.786187844710712 0.952727431263461 GO:0051213 dioxygenase activity 8/1988 93/18639 0.0860215053763441 0.806516518465633 0.788206012328305 0.952727431263461 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 25/1988 268/18639 0.0932835820895522 0.874603967086099 0.789800027301798 0.952727431263461 GO:0019905 syntaxin binding 5/1988 61/18639 0.0819672131147541 0.768504469439588 0.793104956069619 0.952727431263461 GO:0004065 arylsulfatase activity 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0005161 platelet-derived growth factor receptor binding 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0005313 L-glutamate transmembrane transporter activity 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0008195 phosphatidate phosphatase activity 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0008559 ABC-type xenobiotic transporter activity 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0030983 mismatched DNA binding 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0034236 protein kinase A catalytic subunit binding 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0046030 inositol trisphosphate phosphatase activity 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0061783 peptidoglycan muralytic activity 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0098821 BMP receptor activity 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0098847 sequence-specific single stranded DNA binding 1/1988 14/18639 0.0714285714285714 0.669696751940213 0.793939526052884 0.952727431263461 GO:0030165 PDZ domain binding 7/1988 83/18639 0.0843373493975904 0.790726285423384 0.795349666031822 0.953480209868857 GO:0016410 N-acyltransferase activity 8/1988 94/18639 0.0851063829787234 0.797936555503232 0.797942165392205 0.955647549112789 GO:0001216 DNA-binding transcription activator activity 47/1988 491/18639 0.0957230142566191 0.897475484270183 0.806566070014603 0.961129290981224 GO:0004674 protein serine/threonine kinase activity 41/1988 433/18639 0.0946882217090069 0.887773523357233 0.813691625465455 0.961129290981224 GO:0031491 nucleosome binding 6/1988 74/18639 0.0810810810810811 0.760196313013215 0.814666658003784 0.961129290981224 GO:0015144 carbohydrate transmembrane transporter activity 3/1988 40/18639 0.075 0.703181589537223 0.81475746885288 0.961129290981224 GO:0019789 SUMO transferase activity 2/1988 28/18639 0.0714285714285714 0.669696751940213 0.815594452446256 0.961129290981224 GO:0045499 chemorepellent activity 2/1988 28/18639 0.0714285714285714 0.669696751940213 0.815594452446256 0.961129290981224 GO:0050698 proteoglycan sulfotransferase activity 2/1988 28/18639 0.0714285714285714 0.669696751940213 0.815594452446256 0.961129290981224 GO:0051119 sugar transmembrane transporter activity 2/1988 28/18639 0.0714285714285714 0.669696751940213 0.815594452446256 0.961129290981224 GO:0004089 carbonate dehydratase activity 1/1988 15/18639 0.0666666666666667 0.625050301810865 0.815934061473387 0.961129290981224 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1988 15/18639 0.0666666666666667 0.625050301810865 0.815934061473387 0.961129290981224 GO:0005041 low-density lipoprotein particle receptor activity 1/1988 15/18639 0.0666666666666667 0.625050301810865 0.815934061473387 0.961129290981224 GO:0015116 sulfate transmembrane transporter activity 1/1988 15/18639 0.0666666666666667 0.625050301810865 0.815934061473387 0.961129290981224 GO:0015250 water channel activity 1/1988 15/18639 0.0666666666666667 0.625050301810865 0.815934061473387 0.961129290981224 GO:0017081 chloride channel regulator activity 1/1988 15/18639 0.0666666666666667 0.625050301810865 0.815934061473387 0.961129290981224 GO:0033130 acetylcholine receptor binding 1/1988 15/18639 0.0666666666666667 0.625050301810865 0.815934061473387 0.961129290981224 GO:0042809 nuclear vitamin D receptor binding 1/1988 15/18639 0.0666666666666667 0.625050301810865 0.815934061473387 0.961129290981224 GO:0047372 monoacylglycerol lipase activity 1/1988 15/18639 0.0666666666666667 0.625050301810865 0.815934061473387 0.961129290981224 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 46/1988 484/18639 0.0950413223140496 0.891084107953506 0.818781190901751 0.963184350277514 GO:0140767 enzyme-substrate adaptor activity 12/1988 139/18639 0.0863309352517986 0.809417657021264 0.819260251960184 0.963184350277514 GO:0008227 G protein-coupled amine receptor activity 3/1988 41/18639 0.0731707317073171 0.686030819060706 0.827785053206434 0.966897993711758 GO:0004181 metallocarboxypeptidase activity 2/1988 29/18639 0.0689655172413793 0.646603760493998 0.830754841346713 0.966897993711758 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1988 29/18639 0.0689655172413793 0.646603760493998 0.830754841346713 0.966897993711758 GO:0097472 cyclin-dependent protein kinase activity 2/1988 29/18639 0.0689655172413793 0.646603760493998 0.830754841346713 0.966897993711758 GO:0106222 lncRNA binding 2/1988 29/18639 0.0689655172413793 0.646603760493998 0.830754841346713 0.966897993711758 GO:0005543 phospholipid binding 47/1988 497/18639 0.0945674044265594 0.886640770174366 0.830881570602393 0.966897993711758 GO:0008146 sulfotransferase activity 4/1988 53/18639 0.0754716981132075 0.707604115257583 0.830966003617621 0.966897993711758 GO:0017046 peptide hormone binding 4/1988 53/18639 0.0754716981132075 0.707604115257583 0.830966003617621 0.966897993711758 GO:0042626 ATPase-coupled transmembrane transporter activity 8/1988 98/18639 0.0816326530612245 0.7653677165031 0.833533121256046 0.966897993711758 GO:0003688 DNA replication origin binding 1/1988 16/18639 0.0625 0.585984657947686 0.835581993485356 0.966897993711758 GO:0004708 MAP kinase kinase activity 1/1988 16/18639 0.0625 0.585984657947686 0.835581993485356 0.966897993711758 GO:0005024 transforming growth factor beta receptor activity 1/1988 16/18639 0.0625 0.585984657947686 0.835581993485356 0.966897993711758 GO:0008296 3'-5'-DNA exonuclease activity 1/1988 16/18639 0.0625 0.585984657947686 0.835581993485356 0.966897993711758 GO:0015378 sodium:chloride symporter activity 1/1988 16/18639 0.0625 0.585984657947686 0.835581993485356 0.966897993711758 GO:0015562 efflux transmembrane transporter activity 1/1988 16/18639 0.0625 0.585984657947686 0.835581993485356 0.966897993711758 GO:0030275 LRR domain binding 1/1988 16/18639 0.0625 0.585984657947686 0.835581993485356 0.966897993711758 GO:0005244 voltage-gated monoatomic ion channel activity 15/1988 173/18639 0.0867052023121387 0.812926693106617 0.835914275351791 0.966897993711758 GO:0048019 receptor antagonist activity 2/1988 30/18639 0.0666666666666667 0.625050301810865 0.844781023213902 0.974781132686396 GO:0070566 adenylyltransferase activity 2/1988 30/18639 0.0666666666666667 0.625050301810865 0.844781023213902 0.974781132686396 GO:0022843 voltage-gated monoatomic cation channel activity 12/1988 143/18639 0.0839160839160839 0.786776603678012 0.84705357524726 0.974781132686396 GO:0022832 voltage-gated channel activity 15/1988 175/18639 0.0857142857142857 0.803636102328255 0.848054112615108 0.974781132686396 GO:1902936 phosphatidylinositol bisphosphate binding 9/1988 111/18639 0.0810810810810811 0.760196313013215 0.849656939107328 0.974781132686396 GO:0008484 sulfuric ester hydrolase activity 1/1988 17/18639 0.0588235294117647 0.551514972186058 0.853133569329802 0.974781132686396 GO:0031489 myosin V binding 1/1988 17/18639 0.0588235294117647 0.551514972186058 0.853133569329802 0.974781132686396 GO:0032183 SUMO binding 1/1988 17/18639 0.0588235294117647 0.551514972186058 0.853133569329802 0.974781132686396 GO:0036041 long-chain fatty acid binding 1/1988 17/18639 0.0588235294117647 0.551514972186058 0.853133569329802 0.974781132686396 GO:0038191 neuropilin binding 1/1988 17/18639 0.0588235294117647 0.551514972186058 0.853133569329802 0.974781132686396 GO:0045125 bioactive lipid receptor activity 1/1988 17/18639 0.0588235294117647 0.551514972186058 0.853133569329802 0.974781132686396 GO:0046965 nuclear retinoid X receptor binding 1/1988 17/18639 0.0588235294117647 0.551514972186058 0.853133569329802 0.974781132686396 GO:0070402 NADPH binding 1/1988 17/18639 0.0588235294117647 0.551514972186058 0.853133569329802 0.974781132686396 GO:0017147 Wnt-protein binding 2/1988 31/18639 0.0645161290322581 0.604887388849224 0.857742338994269 0.977296696814799 GO:0047499 calcium-independent phospholipase A2 activity 2/1988 31/18639 0.0645161290322581 0.604887388849224 0.857742338994269 0.977296696814799 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1988 31/18639 0.0645161290322581 0.604887388849224 0.857742338994269 0.977296696814799 GO:0015631 tubulin binding 35/1988 385/18639 0.0909090909090909 0.85234132065118 0.864387076564513 0.981645135501074 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1988 18/18639 0.0555555555555556 0.520875251509054 0.868812361305548 0.981645135501074 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1988 18/18639 0.0555555555555556 0.520875251509054 0.868812361305548 0.981645135501074 GO:0004970 glutamate-gated receptor activity 1/1988 18/18639 0.0555555555555556 0.520875251509054 0.868812361305548 0.981645135501074 GO:0005372 water transmembrane transporter activity 1/1988 18/18639 0.0555555555555556 0.520875251509054 0.868812361305548 0.981645135501074 GO:0015280 ligand-gated sodium channel activity 1/1988 18/18639 0.0555555555555556 0.520875251509054 0.868812361305548 0.981645135501074 GO:0015373 monoatomic anion:sodium symporter activity 1/1988 18/18639 0.0555555555555556 0.520875251509054 0.868812361305548 0.981645135501074 GO:0016854 racemase and epimerase activity 1/1988 18/18639 0.0555555555555556 0.520875251509054 0.868812361305548 0.981645135501074 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/1988 18/18639 0.0555555555555556 0.520875251509054 0.868812361305548 0.981645135501074 GO:0047498 calcium-dependent phospholipase A2 activity 2/1988 32/18639 0.0625 0.585984657947686 0.869706248276906 0.981744402596174 GO:0005253 monoatomic anion channel activity 8/1988 103/18639 0.0776699029126214 0.728213943857319 0.870879973254109 0.982159080947689 GO:0016279 protein-lysine N-methyltransferase activity 5/1988 69/18639 0.072463768115942 0.679402501968332 0.872210207022243 0.982749335941806 GO:0017116 single-stranded DNA helicase activity 4/1988 58/18639 0.0689655172413793 0.646603760493998 0.879239370443502 0.982881587408632 GO:0008017 microtubule binding 24/1988 276/18639 0.0869565217391304 0.815283002361998 0.880512909063831 0.982881587408632 GO:0030276 clathrin binding 3/1988 46/18639 0.0652173913043478 0.611462251771498 0.881705878294049 0.982881587408632 GO:0008509 monoatomic anion transmembrane transporter activity 12/1988 149/18639 0.0805369127516778 0.755094324335273 0.882386390461438 0.982881587408632 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1988 19/18639 0.0526315789473684 0.493460764587525 0.882818108887556 0.982881587408632 GO:0008574 plus-end-directed microtubule motor activity 1/1988 19/18639 0.0526315789473684 0.493460764587525 0.882818108887556 0.982881587408632 GO:0042577 lipid phosphatase activity 1/1988 19/18639 0.0526315789473684 0.493460764587525 0.882818108887556 0.982881587408632 GO:0042800 histone H3K4 methyltransferase activity 1/1988 19/18639 0.0526315789473684 0.493460764587525 0.882818108887556 0.982881587408632 GO:0042834 peptidoglycan binding 1/1988 19/18639 0.0526315789473684 0.493460764587525 0.882818108887556 0.982881587408632 GO:0046624 sphingolipid transporter activity 1/1988 19/18639 0.0526315789473684 0.493460764587525 0.882818108887556 0.982881587408632 GO:0099589 serotonin receptor activity 1/1988 19/18639 0.0526315789473684 0.493460764587525 0.882818108887556 0.982881587408632 GO:0140036 ubiquitin-modified protein reader activity 1/1988 19/18639 0.0526315789473684 0.493460764587525 0.882818108887556 0.982881587408632 GO:0141147 intracellularly calcium-gated channel activity 1/1988 19/18639 0.0526315789473684 0.493460764587525 0.882818108887556 0.982881587408632 GO:0140299 molecular sensor activity 5/1988 71/18639 0.0704225352112676 0.660264403321337 0.88742132304799 0.987104266184887 GO:0099095 ligand-gated monoatomic anion channel activity 3/1988 47/18639 0.0638297872340425 0.598452416627424 0.890487176180323 0.98826618442945 GO:0015020 glucuronosyltransferase activity 2/1988 34/18639 0.0588235294117647 0.551514972186058 0.890900057884676 0.98826618442945 GO:0019825 oxygen binding 2/1988 34/18639 0.0588235294117647 0.551514972186058 0.890900057884676 0.98826618442945 GO:0004867 serine-type endopeptidase inhibitor activity 7/1988 95/18639 0.0736842105263158 0.690845070422535 0.892155422610371 0.988677276921146 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/1988 60/18639 0.0666666666666667 0.625050301810865 0.894912390871896 0.988677276921146 GO:0001614 purinergic nucleotide receptor activity 1/1988 20/18639 0.05 0.468787726358149 0.895329258164223 0.988677276921146 GO:0016004 phospholipase activator activity 1/1988 20/18639 0.05 0.468787726358149 0.895329258164223 0.988677276921146 GO:0016502 nucleotide receptor activity 1/1988 20/18639 0.05 0.468787726358149 0.895329258164223 0.988677276921146 GO:0008188 neuropeptide receptor activity 3/1988 48/18639 0.0625 0.585984657947686 0.898679538077763 0.991417293851821 GO:0004623 phospholipase A2 activity 2/1988 35/18639 0.0571428571428571 0.53575740155217 0.900252485221768 0.991417293851821 GO:0140566 histone reader activity 2/1988 35/18639 0.0571428571428571 0.53575740155217 0.900252485221768 0.991417293851821 GO:0030695 GTPase regulator activity 44/1988 489/18639 0.0899795501022495 0.843626174223254 0.90297775921596 0.991919376459942 GO:0060589 nucleoside-triphosphatase regulator activity 44/1988 490/18639 0.0897959183673469 0.84190448815341 0.905577259313345 0.991919376459942 GO:0015103 inorganic anion transmembrane transporter activity 13/1988 165/18639 0.0787878787878788 0.738695811231022 0.906401227439635 0.991919376459942 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/1988 21/18639 0.0476190476190476 0.446464501293475 0.906505230814179 0.991919376459942 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1988 21/18639 0.0476190476190476 0.446464501293475 0.906505230814179 0.991919376459942 GO:0051010 microtubule plus-end binding 1/1988 21/18639 0.0476190476190476 0.446464501293475 0.906505230814179 0.991919376459942 GO:0003678 DNA helicase activity 5/1988 74/18639 0.0675675675675676 0.633496927511012 0.90730934532447 0.991919376459942 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/1988 86/18639 0.0697674418604651 0.654122408871836 0.907697783902538 0.991919376459942 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/1988 36/18639 0.0555555555555556 0.520875251509054 0.908852236559356 0.991919376459942 GO:0005484 SNAP receptor activity 2/1988 36/18639 0.0555555555555556 0.520875251509054 0.908852236559356 0.991919376459942 GO:0005243 gap junction channel activity 1/1988 22/18639 0.0454545454545455 0.42617066032559 0.916488451414749 0.996681190913539 GO:0008093 cytoskeletal anchor activity 1/1988 22/18639 0.0454545454545455 0.42617066032559 0.916488451414749 0.996681190913539 GO:0015377 chloride:monoatomic cation symporter activity 1/1988 22/18639 0.0454545454545455 0.42617066032559 0.916488451414749 0.996681190913539 GO:0033691 sialic acid binding 1/1988 22/18639 0.0454545454545455 0.42617066032559 0.916488451414749 0.996681190913539 GO:0016493 C-C chemokine receptor activity 1/1988 23/18639 0.0434782608695652 0.407641501180999 0.925406158810542 0.999999999948825 GO:0000217 DNA secondary structure binding 2/1988 39/18639 0.0512820512820513 0.480807924469896 0.930661315440066 0.999999999948825 GO:0004864 protein phosphatase inhibitor activity 3/1988 53/18639 0.0566037735849057 0.530703086443187 0.931906412324108 0.999999999948825 GO:0101005 deubiquitinase activity 8/1988 115/18639 0.0695652173913043 0.652226401889598 0.933170152138192 0.999999999948825 GO:0004806 triacylglycerol lipase activity 1/1988 24/18639 0.0416666666666667 0.390656438631791 0.933372024532751 0.999999999948825 GO:0005540 hyaluronic acid binding 1/1988 24/18639 0.0416666666666667 0.390656438631791 0.933372024532751 0.999999999948825 GO:0030215 semaphorin receptor binding 1/1988 24/18639 0.0416666666666667 0.390656438631791 0.933372024532751 0.999999999948825 GO:0030552 cAMP binding 1/1988 24/18639 0.0416666666666667 0.390656438631791 0.933372024532751 0.999999999948825 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/1988 24/18639 0.0416666666666667 0.390656438631791 0.933372024532751 0.999999999948825 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/1988 24/18639 0.0416666666666667 0.390656438631791 0.933372024532751 0.999999999948825 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/1988 24/18639 0.0416666666666667 0.390656438631791 0.933372024532751 0.999999999948825 GO:0005096 GTPase activator activity 22/1988 271/18639 0.0811808118081181 0.761131363828729 0.933491677268462 0.999999999948825 GO:0015370 solute:sodium symporter activity 5/1988 79/18639 0.0632911392405063 0.59340218526348 0.933670345869861 0.999999999948825 GO:0019783 ubiquitin-like protein peptidase activity 9/1988 127/18639 0.0708661417322835 0.66442354916903 0.934374520318215 0.999999999948825 GO:0071855 neuropeptide receptor binding 2/1988 40/18639 0.05 0.468787726358149 0.936761517892023 0.999999999948825 GO:1901981 phosphatidylinositol phosphate binding 14/1988 185/18639 0.0756756756756757 0.709516558812334 0.937988164178467 0.999999999948825 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/1988 25/18639 0.04 0.375030181086519 0.94048759881311 0.999999999948825 GO:0000149 SNARE binding 7/1988 106/18639 0.0660377358490566 0.619153600850385 0.943761571161753 0.999999999948825 GO:0019212 phosphatase inhibitor activity 3/1988 56/18639 0.0535714285714286 0.50227256395516 0.94668883582653 0.999999999948825 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1988 26/18639 0.0384615384615385 0.360605943352422 0.946843602550058 0.999999999948825 GO:0004950 chemokine receptor activity 1/1988 26/18639 0.0384615384615385 0.360605943352422 0.946843602550058 0.999999999948825 GO:0008066 glutamate receptor activity 1/1988 26/18639 0.0384615384615385 0.360605943352422 0.946843602550058 0.999999999948825 GO:0008157 protein phosphatase 1 binding 1/1988 26/18639 0.0384615384615385 0.360605943352422 0.946843602550058 0.999999999948825 GO:0019865 immunoglobulin binding 1/1988 26/18639 0.0384615384615385 0.360605943352422 0.946843602550058 0.999999999948825 GO:0034237 protein kinase A regulatory subunit binding 1/1988 26/18639 0.0384615384615385 0.360605943352422 0.946843602550058 0.999999999948825 GO:0004402 histone acetyltransferase activity 2/1988 42/18639 0.0476190476190476 0.446464501293475 0.947466609554384 0.999999999948825 GO:0005254 chloride channel activity 5/1988 83/18639 0.0602409638554217 0.564804489588131 0.949695686475512 0.999999999948825 GO:0004843 cysteine-type deubiquitinase activity 7/1988 108/18639 0.0648148148148148 0.60768779342723 0.950327435749539 0.999999999948825 GO:0005245 voltage-gated calcium channel activity 2/1988 43/18639 0.0465116279069767 0.436081605914557 0.952148227495194 0.999999999948825 GO:0015252 proton channel activity 1/1988 27/18639 0.037037037037037 0.347250167672703 0.952521081630834 0.999999999948825 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1988 27/18639 0.037037037037037 0.347250167672703 0.952521081630834 0.999999999948825 GO:0035255 ionotropic glutamate receptor binding 1/1988 27/18639 0.037037037037037 0.347250167672703 0.952521081630834 0.999999999948825 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/1988 27/18639 0.037037037037037 0.347250167672703 0.952521081630834 0.999999999948825 GO:0008528 G protein-coupled peptide receptor activity 8/1988 122/18639 0.0655737704918033 0.614803575551671 0.955771373468972 0.999999999948825 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/1988 44/18639 0.0454545454545455 0.42617066032559 0.956429424657237 0.999999999948825 GO:0005242 inward rectifier potassium channel activity 1/1988 28/18639 0.0357142857142857 0.334848375970106 0.9575924382673 0.999999999948825 GO:0046966 nuclear thyroid hormone receptor binding 1/1988 28/18639 0.0357142857142857 0.334848375970106 0.9575924382673 0.999999999948825 GO:0051959 dynein light intermediate chain binding 1/1988 28/18639 0.0357142857142857 0.334848375970106 0.9575924382673 0.999999999948825 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/1988 28/18639 0.0357142857142857 0.334848375970106 0.9575924382673 0.999999999948825 GO:0015085 calcium ion transmembrane transporter activity 10/1988 147/18639 0.0680272108843537 0.63780643041925 0.95862763423072 0.999999999948825 GO:0015079 potassium ion transmembrane transporter activity 11/1988 160/18639 0.06875 0.644583123742455 0.961356162895379 0.999999999948825 GO:0003785 actin monomer binding 1/1988 29/18639 0.0344827586206897 0.323301880246999 0.962122352443035 0.999999999948825 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/1988 29/18639 0.0344827586206897 0.323301880246999 0.962122352443035 0.999999999948825 GO:0099604 ligand-gated calcium channel activity 1/1988 29/18639 0.0344827586206897 0.323301880246999 0.962122352443035 0.999999999948825 GO:0140030 modification-dependent protein binding 12/1988 173/18639 0.069364161849711 0.650341354485293 0.963979408829335 0.999999999948825 GO:0046873 metal ion transmembrane transporter activity 37/1988 450/18639 0.0822222222222222 0.7708953722334 0.966002511430285 0.999999999948825 GO:0046906 tetrapyrrole binding 10/1988 152/18639 0.0657894736842105 0.616825955734406 0.968884176582683 0.999999999948825 GO:0015081 sodium ion transmembrane transporter activity 11/1988 164/18639 0.0670731707317073 0.62886158413898 0.969022363390079 0.999999999948825 GO:0001653 peptide receptor activity 8/1988 128/18639 0.0625 0.585984657947686 0.969413881886385 0.999999999948825 GO:0005184 neuropeptide hormone activity 1/1988 31/18639 0.032258064516129 0.302443694424612 0.969782814047767 0.999999999948825 GO:0005452 solute:inorganic anion antiporter activity 1/1988 31/18639 0.032258064516129 0.302443694424612 0.969782814047767 0.999999999948825 GO:0022824 transmitter-gated monoatomic ion channel activity 3/1988 63/18639 0.0476190476190476 0.446464501293475 0.970356320891789 0.999999999948825 GO:0022835 transmitter-gated channel activity 3/1988 63/18639 0.0476190476190476 0.446464501293475 0.970356320891789 0.999999999948825 GO:0003774 cytoskeletal motor activity 10/1988 153/18639 0.065359477124183 0.612794413540064 0.97063696127504 0.999999999948825 GO:0020037 heme binding 9/1988 142/18639 0.0633802816901408 0.594237962989203 0.972515854856328 0.999999999948825 GO:0042910 xenobiotic transmembrane transporter activity 1/1988 32/18639 0.03125 0.292992328973843 0.973011090362956 0.999999999948825 GO:0160041 neuropeptide activity 1/1988 32/18639 0.03125 0.292992328973843 0.973011090362956 0.999999999948825 GO:0005272 sodium channel activity 2/1988 51/18639 0.0392156862745098 0.367676648124038 0.977609854713708 0.999999999948825 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1988 34/18639 0.0294117647058824 0.275757486093029 0.97847021923676 0.999999999948825 GO:0015108 chloride transmembrane transporter activity 7/1988 121/18639 0.0578512396694215 0.542399022232569 0.978664229744726 0.999999999948825 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/1988 53/18639 0.0377358490566038 0.353802057628792 0.981539482786059 0.999999999948825 GO:0030594 neurotransmitter receptor activity 5/1988 97/18639 0.0515463917525773 0.483286315833143 0.98188566506062 0.999999999948825 GO:0000993 RNA polymerase II complex binding 1/1988 36/18639 0.0277777777777778 0.260437625754527 0.982825555233038 0.999999999948825 GO:0004190 aspartic-type endopeptidase activity 1/1988 36/18639 0.0277777777777778 0.260437625754527 0.982825555233038 0.999999999948825 GO:0030551 cyclic nucleotide binding 1/1988 37/18639 0.027027027027027 0.253398771004405 0.984660893414876 0.999999999948825 GO:0070001 aspartic-type peptidase activity 1/1988 37/18639 0.027027027027027 0.253398771004405 0.984660893414876 0.999999999948825 GO:0022836 gated channel activity 23/1988 318/18639 0.0723270440251572 0.678120610455184 0.985619755281859 0.999999999948825 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/1988 56/18639 0.0357142857142857 0.334848375970106 0.986207360630386 0.999999999948825 GO:0000146 microfilament motor activity 1/1988 38/18639 0.0263157894736842 0.246730382293763 0.986300187248401 0.999999999948825 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/1988 73/18639 0.0410958904109589 0.385304980568342 0.98758832398768 0.999999999948825 GO:0032451 demethylase activity 1/1988 40/18639 0.025 0.234393863179074 0.989072133475037 0.999999999948825 GO:0005262 calcium channel activity 7/1988 131/18639 0.0534351145038168 0.500994516718632 0.989299599720348 0.999999999948825 GO:0043175 RNA polymerase core enzyme binding 1/1988 42/18639 0.0238095238095238 0.223232250646738 0.991283443396982 0.999999999948825 GO:0042393 histone binding 16/1988 247/18639 0.0647773279352227 0.607336325646185 0.991493349497117 0.999999999948825 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/1988 43/18639 0.0232558139534884 0.218040802957279 0.992215234251787 0.999999999948825 GO:0005216 monoatomic ion channel activity 33/1988 448/18639 0.0736607142857143 0.690624775438344 0.993314079154638 0.999999999948825 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1988 46/18639 0.0217391304347826 0.2038207505905 0.994454629633235 0.999999999948825 GO:0005261 monoatomic cation channel activity 23/1988 341/18639 0.0674486803519062 0.632382270160553 0.99526798276968 0.999999999948825 GO:0035091 phosphatidylinositol binding 18/1988 284/18639 0.0633802816901408 0.594237962989203 0.995832741722131 0.999999999948825 GO:0098960 postsynaptic neurotransmitter receptor activity 2/1988 69/18639 0.0289855072463768 0.271761000787333 0.996190701261283 0.999999999948825 GO:0003730 mRNA 3'-UTR binding 16/1988 262/18639 0.0610687022900763 0.572565161964151 0.996354342830627 0.999999999948825 GO:0061630 ubiquitin protein ligase activity 23/1988 353/18639 0.0651558073654391 0.610884855877475 0.99744998442654 0.999999999948825 GO:0035064 methylated histone binding 2/1988 74/18639 0.027027027027027 0.253398771004405 0.997697148720625 0.999999999948825 GO:0140034 methylation-dependent protein binding 2/1988 76/18639 0.0263157894736842 0.246730382293763 0.998119145825071 0.999999999948825 GO:0004842 ubiquitin-protein transferase activity 30/1988 449/18639 0.066815144766147 0.626442396024253 0.998714034380481 0.999999999948825 GO:0036002 pre-mRNA binding 1/1988 59/18639 0.0169491525423729 0.158911093680728 0.998725691247007 0.999999999948825 GO:0061659 ubiquitin-like protein ligase activity 23/1988 372/18639 0.0618279569892473 0.579683747647173 0.999088039872689 0.999999999948825 GO:0016755 aminoacyltransferase activity 33/1988 496/18639 0.0665322580645161 0.623790119750763 0.999286975055228 0.999999999948825 GO:0019787 ubiquitin-like protein transferase activity 31/1988 479/18639 0.0647181628392484 0.606781608229754 0.999490889710562 0.999999999948825 GO:0003777 microtubule motor activity 1/1988 68/18639 0.0147058823529412 0.137878743046514 0.999539901226778 0.999999999948825 GO:0022834 ligand-gated channel activity 8/1988 188/18639 0.0425531914893617 0.398968277751616 0.999570343191818 0.999999999948825 GO:0005179 hormone activity 4/1988 132/18639 0.0303030303030303 0.284113773550393 0.999743023090195 0.999999999948825 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/1988 181/18639 0.0386740331491713 0.362598241381994 0.999769716554086 0.999999999948825 GO:0015276 ligand-gated monoatomic ion channel activity 7/1988 186/18639 0.0376344086021505 0.352850976828714 0.999847426214593 0.999999999948825 GO:0004497 monooxygenase activity 2/1988 106/18639 0.0188679245283019 0.176901028814396 0.999914848768391 0.999999999948825 GO:0099094 ligand-gated monoatomic cation channel activity 3/1988 136/18639 0.0220588235294118 0.206818114569772 0.999969118623384 0.999999999948825 GO:0045182 translation regulator activity 11/1988 356/18639 0.0308988764044944 0.289700280333687 0.999999982237859 0.999999999948825 GO:0030371 translation repressor activity 6/1988 329/18639 0.0182370820668693 0.170986404750693 0.999999999948825 0.999999999948825