ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0045296 cadherin binding 11/68 334/18639 0.0329341317365269 9.02734237407538 3.20085622851023e-08 9.21846593810945e-06 GO:0003779 actin binding 11/68 443/18639 0.0248306997742664 6.80616783959633 5.47066445256472e-07 7.8777568116932e-05 GO:0071723 lipopeptide binding 3/68 10/18639 0.3 82.2308823529412 5.47206449457531e-06 0.00052531819147923 GO:0048306 calcium-dependent protein binding 5/68 80/18639 0.0625 17.1314338235294 1.08267980342978e-05 0.000630564598902259 GO:0051015 actin filament binding 7/68 209/18639 0.0334928229665072 9.18048128342246 1.09473020642753e-05 0.000630564598902259 GO:0003823 antigen binding 6/68 174/18639 0.0344827586206897 9.45182555780933 4.1150134862875e-05 0.00174815543976761 GO:0003735 structural constituent of ribosome 6/68 175/18639 0.0342857142857143 9.39781512605042 4.24898891610184e-05 0.00174815543976761 GO:0023026 MHC class II protein complex binding 3/68 27/18639 0.111111111111111 30.4558823529412 0.000127583914273333 0.00459302091383999 GO:0023023 MHC protein complex binding 3/68 37/18639 0.0810810810810811 22.2245627980922 0.000330186190893305 0.0105659581085857 GO:0032395 MHC class II receptor activity 2/68 10/18639 0.2 54.8205882352941 0.000579121105963353 0.0153944574939533 GO:0050786 RAGE receptor binding 2/68 11/18639 0.181818181818182 49.8368983957219 0.000706147035151238 0.0153944574939533 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/68 11/18639 0.181818181818182 49.8368983957219 0.000706147035151238 0.0153944574939533 GO:0038187 pattern recognition receptor activity 3/68 48/18639 0.0625 17.1314338235294 0.000714226798132301 0.0153944574939533 GO:0005200 structural constituent of cytoskeleton 4/68 112/18639 0.0357142857142857 9.78939075630252 0.000748341683733843 0.0153944574939533 GO:0044548 S100 protein binding 2/68 14/18639 0.142857142857143 39.1575630252101 0.00116011794133406 0.0222742644736139 GO:0004866 endopeptidase inhibitor activity 4/68 161/18639 0.0248447204968944 6.8100109609061 0.00284302687775862 0.04640179034311 GO:0033293 monocarboxylic acid binding 3/68 79/18639 0.0379746835443038 10.4089724497394 0.00301283616830536 0.04640179034311 GO:0099186 structural constituent of postsynapse 2/68 23/18639 0.0869565217391304 23.8350383631714 0.00315777002928473 0.04640179034311 GO:0001618 virus receptor activity 3/68 81/18639 0.037037037037037 10.1519607843137 0.00323380603413563 0.04640179034311 GO:0140272 exogenous protein binding 3/68 82/18639 0.0365853658536585 10.028156384505 0.00334792220623244 0.04640179034311 GO:0030414 peptidase inhibitor activity 4/68 169/18639 0.0236686390532544 6.48764357814132 0.0033834638791851 0.04640179034311 GO:0030246 carbohydrate binding 5/68 280/18639 0.0178571428571429 4.89469537815126 0.00355850411569329 0.0465840538781667 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/68 86/18639 0.0348837209302326 9.56173050615595 0.00382898185728528 0.047945511952094 GO:0070006 metalloaminopeptidase activity 2/68 26/18639 0.0769230769230769 21.0848416289593 0.00402792343410774 0.0483350812092929 GO:0061135 endopeptidase regulator activity 4/68 184/18639 0.0217391304347826 5.95875959079284 0.00457802105104276 0.051758148396495 GO:0031406 carboxylic acid binding 4/68 187/18639 0.0213903743315508 5.86316451714376 0.00484695954562821 0.051758148396495 GO:0003785 actin monomer binding 2/68 29/18639 0.0689655172413793 18.9036511156187 0.00499647999223611 0.051758148396495 GO:0043177 organic acid binding 4/68 189/18639 0.0211640211640212 5.80112044817927 0.00503204220521479 0.051758148396495 GO:0098918 structural constituent of synapse 2/68 30/18639 0.0666666666666667 18.2735294117647 0.00534082075409724 0.0530398750751726 GO:1902936 phosphatidylinositol bisphosphate binding 3/68 111/18639 0.027027027027027 7.40818759936407 0.00777972516864057 0.0746853616189495 GO:0004177 aminopeptidase activity 2/68 40/18639 0.05 13.7051470588235 0.00935479745089187 0.0816577636362427 GO:0140662 ATP-dependent protein folding chaperone 2/68 40/18639 0.05 13.7051470588235 0.00935479745089187 0.0816577636362427 GO:0061134 peptidase regulator activity 4/68 226/18639 0.0176991150442478 4.85137948984904 0.00935661874998614 0.0816577636362427 GO:0042605 peptide antigen binding 2/68 45/18639 0.0444444444444444 12.1823529411765 0.0117353382858741 0.0882631178293849 GO:0033218 amide binding 4/68 247/18639 0.0161943319838057 4.43891402714932 0.0126427888369764 0.0882631178293849 GO:0001784 phosphotyrosine residue binding 2/68 47/18639 0.0425531914893617 11.6639549436796 0.0127542892222208 0.0882631178293849 GO:0005504 fatty acid binding 2/68 47/18639 0.0425531914893617 11.6639549436796 0.0127542892222208 0.0882631178293849 GO:0061749 forked DNA-dependent helicase activity 2/68 47/18639 0.0425531914893617 11.6639549436796 0.0127542892222208 0.0882631178293849 GO:1990518 single-stranded 3'-5' DNA helicase activity 2/68 47/18639 0.0425531914893617 11.6639549436796 0.0127542892222208 0.0882631178293849 GO:0042277 peptide binding 4/68 249/18639 0.0160642570281124 4.40326009922041 0.0129895999747248 0.0882631178293849 GO:0009378 four-way junction helicase activity 2/68 48/18639 0.0416666666666667 11.4209558823529 0.0132777701971812 0.0882631178293849 GO:0036121 double-stranded DNA helicase activity 2/68 48/18639 0.0416666666666667 11.4209558823529 0.0132777701971812 0.0882631178293849 GO:0043138 3'-5' DNA helicase activity 2/68 48/18639 0.0416666666666667 11.4209558823529 0.0132777701971812 0.0882631178293849 GO:0002020 protease binding 3/68 136/18639 0.0220588235294118 6.0463884083045 0.0134846430017116 0.0882631178293849 GO:0016830 carbon-carbon lyase activity 2/68 51/18639 0.0392156862745098 10.7491349480969 0.014903363925491 0.0953815291231425 GO:0016887 ATP hydrolysis activity 5/68 417/18639 0.0119904076738609 3.2866060093102 0.0180341234545443 0.11290929467193 GO:0017116 single-stranded DNA helicase activity 2/68 58/18639 0.0344827586206897 9.45182555780933 0.0190089741855062 0.115377393489669 GO:0140375 immune receptor activity 3/68 156/18639 0.0192307692307692 5.27121040723982 0.0193886590524271 0.115377393489669 GO:0045309 protein phosphorylated amino acid binding 2/68 59/18639 0.0338983050847458 9.29162512462612 0.0196301815312284 0.115377393489669 GO:0001664 G protein-coupled receptor binding 4/68 297/18639 0.0134680134680135 3.69162210338681 0.0231981625459875 0.132891309329066 GO:0019843 rRNA binding 2/68 65/18639 0.0307692307692308 8.43393665158371 0.0235328360270221 0.132891309329066 GO:0008235 metalloexopeptidase activity 2/68 66/18639 0.0303030303030303 8.30614973262032 0.0242118864804537 0.134096602045589 GO:0003678 DNA helicase activity 2/68 74/18639 0.027027027027027 7.40818759936407 0.029926713350951 0.157704143734749 GO:0048029 monosaccharide binding 2/68 74/18639 0.027027027027027 7.40818759936407 0.029926713350951 0.157704143734749 GO:1901981 phosphatidylinositol phosphate binding 3/68 185/18639 0.0162162162162162 4.44491255961844 0.0301171107826777 0.157704143734749 GO:0044183 protein folding chaperone 2/68 75/18639 0.0266666666666667 7.30941176470588 0.0306754051909696 0.157759226696415 GO:0098631 cell adhesion mediator activity 2/68 76/18639 0.0263157894736842 7.21323529411765 0.0314315167176747 0.158811873941935 GO:0001094 TFIID-class transcription factor complex binding 1/68 10/18639 0.1 27.4102941176471 0.0358980171483673 0.164105221249679 GO:0003796 lysozyme activity 1/68 10/18639 0.1 27.4102941176471 0.0358980171483673 0.164105221249679 GO:0005522 profilin binding 1/68 10/18639 0.1 27.4102941176471 0.0358980171483673 0.164105221249679 GO:0030957 Tat protein binding 1/68 10/18639 0.1 27.4102941176471 0.0358980171483673 0.164105221249679 GO:0032052 bile acid binding 1/68 10/18639 0.1 27.4102941176471 0.0358980171483673 0.164105221249679 GO:0050308 sugar-phosphatase activity 1/68 10/18639 0.1 27.4102941176471 0.0358980171483673 0.164105221249679 GO:0016829 lyase activity 3/68 200/18639 0.015 4.11154411764706 0.0366712363938475 0.164827136962783 GO:0008503 benzodiazepine receptor activity 1/68 11/18639 0.0909090909090909 24.918449197861 0.0394172041596893 0.164827136962783 GO:0019203 carbohydrate phosphatase activity 1/68 11/18639 0.0909090909090909 24.918449197861 0.0394172041596893 0.164827136962783 GO:0019215 intermediate filament binding 1/68 11/18639 0.0909090909090909 24.918449197861 0.0394172041596893 0.164827136962783 GO:0050998 nitric-oxide synthase binding 1/68 11/18639 0.0909090909090909 24.918449197861 0.0394172041596893 0.164827136962783 GO:0004859 phospholipase inhibitor activity 1/68 12/18639 0.0833333333333333 22.8419117647059 0.0429237335840581 0.164827136962783 GO:0005049 nuclear export signal receptor activity 1/68 12/18639 0.0833333333333333 22.8419117647059 0.0429237335840581 0.164827136962783 GO:0016208 AMP binding 1/68 12/18639 0.0833333333333333 22.8419117647059 0.0429237335840581 0.164827136962783 GO:0016801 hydrolase activity, acting on ether bonds 1/68 12/18639 0.0833333333333333 22.8419117647059 0.0429237335840581 0.164827136962783 GO:0016803 ether hydrolase activity 1/68 12/18639 0.0833333333333333 22.8419117647059 0.0429237335840581 0.164827136962783 GO:0042301 phosphate ion binding 1/68 12/18639 0.0833333333333333 22.8419117647059 0.0429237335840581 0.164827136962783 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/68 12/18639 0.0833333333333333 22.8419117647059 0.0429237335840581 0.164827136962783 GO:0051219 phosphoprotein binding 2/68 93/18639 0.021505376344086 5.89468690702087 0.0453615063329044 0.169218775669265 GO:0030955 potassium ion binding 1/68 13/18639 0.0769230769230769 21.0848416289593 0.0464176502703886 0.169218775669265 GO:0035325 Toll-like receptor binding 1/68 13/18639 0.0769230769230769 21.0848416289593 0.0464176502703886 0.169218775669265 GO:0039706 co-receptor binding 1/68 13/18639 0.0769230769230769 21.0848416289593 0.0464176502703886 0.169218775669265 GO:0004867 serine-type endopeptidase inhibitor activity 2/68 95/18639 0.0210526315789474 5.77058823529412 0.047126455328579 0.169655239182884 GO:0032036 myosin heavy chain binding 1/68 14/18639 0.0714285714285714 19.578781512605 0.0498989989110851 0.175255020565762 GO:0061783 peptidoglycan muralytic activity 1/68 14/18639 0.0714285714285714 19.578781512605 0.0498989989110851 0.175255020565762 GO:0000287 magnesium ion binding 3/68 230/18639 0.0130434782608696 3.5752557544757 0.0517854419255242 0.177094522536824 GO:0000774 adenyl-nucleotide exchange factor activity 1/68 15/18639 0.0666666666666667 18.2735294117647 0.053367824042578 0.177094522536824 GO:0005523 tropomyosin binding 1/68 15/18639 0.0666666666666667 18.2735294117647 0.053367824042578 0.177094522536824 GO:0140776 protein-containing complex destabilizing activity 1/68 15/18639 0.0666666666666667 18.2735294117647 0.053367824042578 0.177094522536824 GO:0008238 exopeptidase activity 2/68 102/18639 0.0196078431372549 5.37456747404844 0.0534973036829988 0.177094522536824 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/68 16/18639 0.0625 17.1314338235294 0.0568241700458586 0.181837344146748 GO:0055102 lipase inhibitor activity 1/68 16/18639 0.0625 17.1314338235294 0.0568241700458586 0.181837344146748 GO:0097027 ubiquitin-protein transferase activator activity 1/68 16/18639 0.0625 17.1314338235294 0.0568241700458586 0.181837344146748 GO:0005496 steroid binding 2/68 108/18639 0.0185185185185185 5.07598039215686 0.0591870000667178 0.186636638390763 GO:0036041 long-chain fatty acid binding 1/68 17/18639 0.0588235294117647 16.1237024221453 0.0602680811470172 0.186636638390763 GO:0046965 nuclear retinoid X receptor binding 1/68 17/18639 0.0588235294117647 16.1237024221453 0.0602680811470172 0.186636638390763 GO:0140104 molecular carrier activity 3/68 249/18639 0.0120481927710843 3.30244507441531 0.0626903940802337 0.189511834661653 GO:0070064 proline-rich region binding 1/68 18/18639 0.0555555555555556 15.2279411764706 0.0636996014177728 0.189511834661653 GO:0098641 cadherin binding involved in cell-cell adhesion 1/68 18/18639 0.0555555555555556 15.2279411764706 0.0636996014177728 0.189511834661653 GO:0004857 enzyme inhibitor activity 4/68 416/18639 0.00961538461538462 2.63560520361991 0.0653894599544856 0.189511834661653 GO:0035401 histone H3Y41 kinase activity 2/68 115/18639 0.0173913043478261 4.76700767263427 0.0660760723871701 0.189511834661653 GO:0140801 histone H2AXY142 kinase activity 2/68 115/18639 0.0173913043478261 4.76700767263427 0.0660760723871701 0.189511834661653 GO:0015245 fatty acid transmembrane transporter activity 1/68 19/18639 0.0526315789473684 14.4264705882353 0.0671187747760021 0.189511834661653 GO:0031420 alkali metal ion binding 1/68 19/18639 0.0526315789473684 14.4264705882353 0.0671187747760021 0.189511834661653 GO:0034987 immunoglobulin receptor binding 1/68 19/18639 0.0526315789473684 14.4264705882353 0.0671187747760021 0.189511834661653 GO:0001972 retinoic acid binding 1/68 20/18639 0.05 13.7051470588235 0.0705256449862728 0.197197919961617 GO:0051082 unfolded protein binding 2/68 121/18639 0.0165289256198347 4.53062712688381 0.0721836296987579 0.19989312839656 GO:0070182 DNA polymerase binding 1/68 21/18639 0.0476190476190476 13.0525210084034 0.0739202556603649 0.202752701239858 GO:0016881 acid-amino acid ligase activity 1/68 22/18639 0.0454545454545455 12.4592245989305 0.077302650257803 0.206140400687475 GO:0033691 sialic acid binding 1/68 22/18639 0.0454545454545455 12.4592245989305 0.077302650257803 0.206140400687475 GO:0140517 protein-RNA adaptor activity 1/68 22/18639 0.0454545454545455 12.4592245989305 0.077302650257803 0.206140400687475 GO:0004602 glutathione peroxidase activity 1/68 23/18639 0.0434782608695652 11.9175191815857 0.0806728720863717 0.209313397845721 GO:0005212 structural constituent of eye lens 1/68 23/18639 0.0434782608695652 11.9175191815857 0.0806728720863717 0.209313397845721 GO:0016493 C-C chemokine receptor activity 1/68 23/18639 0.0434782608695652 11.9175191815857 0.0806728720863717 0.209313397845721 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/68 24/18639 0.0416666666666667 11.4209558823529 0.0840309643026445 0.210683454437341 GO:0019957 C-C chemokine binding 1/68 24/18639 0.0416666666666667 11.4209558823529 0.0840309643026445 0.210683454437341 GO:0048027 mRNA 5'-UTR binding 1/68 24/18639 0.0416666666666667 11.4209558823529 0.0840309643026445 0.210683454437341 GO:0035091 phosphatidylinositol binding 3/68 284/18639 0.0105633802816901 2.8954536039768 0.085303480014366 0.210683454437341 GO:0017025 TBP-class protein binding 1/68 25/18639 0.04 10.9641176470588 0.0873769699124975 0.210683454437341 GO:0042974 nuclear retinoic acid receptor binding 1/68 25/18639 0.04 10.9641176470588 0.0873769699124975 0.210683454437341 GO:0120020 cholesterol transfer activity 1/68 25/18639 0.04 10.9641176470588 0.0873769699124975 0.210683454437341 GO:0044325 transmembrane transporter binding 2/68 136/18639 0.0147058823529412 4.03092560553633 0.0881995249338338 0.210683454437341 GO:0001637 G protein-coupled chemoattractant receptor activity 1/68 26/18639 0.0384615384615385 10.5424208144796 0.090710931771633 0.210683454437341 GO:0004950 chemokine receptor activity 1/68 26/18639 0.0384615384615385 10.5424208144796 0.090710931771633 0.210683454437341 GO:0005227 calcium-activated cation channel activity 1/68 26/18639 0.0384615384615385 10.5424208144796 0.090710931771633 0.210683454437341 GO:0043548 phosphatidylinositol 3-kinase binding 1/68 26/18639 0.0384615384615385 10.5424208144796 0.090710931771633 0.210683454437341 GO:0050750 low-density lipoprotein particle receptor binding 1/68 26/18639 0.0384615384615385 10.5424208144796 0.090710931771633 0.210683454437341 GO:0004713 protein tyrosine kinase activity 2/68 140/18639 0.0142857142857143 3.91575630252101 0.0926359845917998 0.213433308499507 GO:0004364 glutathione transferase activity 1/68 27/18639 0.037037037037037 10.1519607843137 0.0940328925860926 0.214166376288898 GO:0097718 disordered domain specific binding 1/68 28/18639 0.0357142857142857 9.78939075630252 0.0973428949127711 0.214166376288898 GO:0031625 ubiquitin protein ligase binding 3/68 302/18639 0.00993377483443709 2.72287689910401 0.09811462849592 0.214166376288898 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/68 29/18639 0.0344827586206897 9.45182555780933 0.100640981159933 0.214166376288898 GO:0043236 laminin binding 1/68 29/18639 0.0344827586206897 9.45182555780933 0.100640981159933 0.214166376288898 GO:0051861 glycolipid binding 1/68 29/18639 0.0344827586206897 9.45182555780933 0.100640981159933 0.214166376288898 GO:0097472 cyclin-dependent protein kinase activity 1/68 29/18639 0.0344827586206897 9.45182555780933 0.100640981159933 0.214166376288898 GO:0140297 DNA-binding transcription factor binding 4/68 488/18639 0.00819672131147541 2.24674541947927 0.102626338029369 0.214166376288898 GO:0016769 transferase activity, transferring nitrogenous groups 1/68 30/18639 0.0333333333333333 9.13676470588235 0.103927193587721 0.214166376288898 GO:0022839 monoatomic ion-gated channel activity 1/68 30/18639 0.0333333333333333 9.13676470588235 0.103927193587721 0.214166376288898 GO:0048019 receptor antagonist activity 1/68 30/18639 0.0333333333333333 9.13676470588235 0.103927193587721 0.214166376288898 GO:0000510 H3-H4 histone complex chaperone activity 2/68 151/18639 0.0132450331125828 3.63050253213868 0.105159396045861 0.214166376288898 GO:0140584 chromatin extrusion motor activity 2/68 151/18639 0.0132450331125828 3.63050253213868 0.105159396045861 0.214166376288898 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/68 151/18639 0.0132450331125828 3.63050253213868 0.105159396045861 0.214166376288898 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/68 151/18639 0.0132450331125828 3.63050253213868 0.105159396045861 0.214166376288898 GO:0015616 DNA translocase activity 2/68 152/18639 0.0131578947368421 3.60661764705882 0.106320045314271 0.214166376288898 GO:0140674 ATP-dependent histone chaperone activity 2/68 152/18639 0.0131578947368421 3.60661764705882 0.106320045314271 0.214166376288898 GO:0070325 lipoprotein particle receptor binding 1/68 31/18639 0.032258064516129 8.84203036053131 0.107201574308664 0.214166376288898 GO:0061775 cohesin loader activity 2/68 153/18639 0.0130718954248366 3.58304498269896 0.107484209954165 0.214166376288898 GO:0051020 GTPase binding 3/68 315/18639 0.00952380952380952 2.61050420168067 0.107826821395452 0.214166376288898 GO:0004386 helicase activity 2/68 155/18639 0.0129032258064516 3.53681214421252 0.109822925108075 0.214957294614856 GO:0120015 sterol transfer activity 1/68 32/18639 0.03125 8.56571691176471 0.11046416528819 0.214957294614856 GO:0140142 nucleocytoplasmic carrier activity 1/68 32/18639 0.03125 8.56571691176471 0.11046416528819 0.214957294614856 GO:0044389 ubiquitin-like protein ligase binding 3/68 322/18639 0.0093167701863354 2.55375411033979 0.113207848047181 0.216886903333749 GO:0140658 ATP-dependent chromatin remodeler activity 2/68 158/18639 0.0126582278481013 3.46965748324646 0.113356367846646 0.216886903333749 GO:0019956 chemokine binding 1/68 33/18639 0.0303030303030303 8.30614973262032 0.113715008345125 0.216886903333749 GO:0003689 DNA clamp loader activity 2/68 160/18639 0.0125 3.42628676470588 0.11572845263416 0.219274962885777 GO:0016831 carboxy-lyase activity 1/68 34/18639 0.0294117647058824 8.06185121107266 0.116954145152205 0.220148979110033 GO:0061631 ubiquitin conjugating enzyme activity 1/68 35/18639 0.0285714285714286 7.83151260504202 0.120181617236573 0.223916711239717 GO:0140713 histone chaperone activity 2/68 164/18639 0.0121951219512195 3.34271879483501 0.120510730007486 0.223916711239717 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/68 36/18639 0.0277777777777778 7.61397058823529 0.123397465980279 0.226359682817326 GO:0055106 ubiquitin-protein transferase regulator activity 1/68 36/18639 0.0277777777777778 7.61397058823529 0.123397465980279 0.226359682817326 GO:0005501 retinoid binding 1/68 38/18639 0.0263157894736842 7.21323529411765 0.129794458251459 0.233630024852625 GO:0019840 isoprenoid binding 1/68 38/18639 0.0263157894736842 7.21323529411765 0.129794458251459 0.233630024852625 GO:0043531 ADP binding 1/68 38/18639 0.0263157894736842 7.21323529411765 0.129794458251459 0.233630024852625 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/68 349/18639 0.00859598853868195 2.35618574077195 0.13488651714947 0.241287682851226 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/68 40/18639 0.025 6.85257352941176 0.136145450139278 0.24203635580316 GO:0005319 lipid transporter activity 2/68 178/18639 0.0112359550561798 3.07980832782551 0.137617556953053 0.243152493266744 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/68 41/18639 0.024390243902439 6.68543758967001 0.139303797867141 0.244631059669125 GO:0019894 kinesin binding 1/68 42/18639 0.0238095238095238 6.52626050420168 0.14245076752759 0.245663599089496 GO:0031492 nucleosomal DNA binding 1/68 42/18639 0.0238095238095238 6.52626050420168 0.14245076752759 0.245663599089496 GO:0042056 chemoattractant activity 1/68 42/18639 0.0238095238095238 6.52626050420168 0.14245076752759 0.245663599089496 GO:0008237 metallopeptidase activity 2/68 184/18639 0.0108695652173913 2.97937979539642 0.145107515537804 0.246640488566274 GO:0005245 voltage-gated calcium channel activity 1/68 43/18639 0.0232558139534884 6.37448700410397 0.145586399500926 0.246640488566274 GO:0048156 tau protein binding 1/68 43/18639 0.0232558139534884 6.37448700410397 0.145586399500926 0.246640488566274 GO:0030547 signaling receptor inhibitor activity 1/68 44/18639 0.0227272727272727 6.22961229946524 0.148710734026304 0.250460183623249 GO:0140597 protein carrier chaperone 2/68 188/18639 0.0106382978723404 2.9159887359199 0.150148153122707 0.251410861042672 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/68 45/18639 0.0222222222222222 6.09117647058823 0.151823811202223 0.252747153908903 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/68 46/18639 0.0217391304347826 5.95875959079284 0.154925670987005 0.256428696806078 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/68 48/18639 0.0208333333333333 5.71047794117647 0.161095897518477 0.263611468666599 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/68 48/18639 0.0208333333333333 5.71047794117647 0.161095897518477 0.263611468666599 GO:0001222 transcription corepressor binding 1/68 49/18639 0.0204081632653061 5.59393757503001 0.164164343485276 0.264130340356198 GO:0016763 pentosyltransferase activity 1/68 49/18639 0.0204081632653061 5.59393757503001 0.164164343485276 0.264130340356198 GO:0060590 ATPase regulator activity 1/68 49/18639 0.0204081632653061 5.59393757503001 0.164164343485276 0.264130340356198 GO:0015631 tubulin binding 3/68 385/18639 0.00779220779220779 2.13586707410237 0.165812402157475 0.265299843451961 GO:0048020 CCR chemokine receptor binding 1/68 50/18639 0.02 5.48205882352941 0.167221730502113 0.26607656566082 GO:0005544 calcium-dependent phospholipid binding 1/68 53/18639 0.0188679245283019 5.17175360710322 0.176327929813375 0.274735872469159 GO:0140296 general transcription initiation factor binding 1/68 53/18639 0.0188679245283019 5.17175360710322 0.176327929813375 0.274735872469159 GO:0008094 ATP-dependent activity, acting on DNA 2/68 210/18639 0.00952380952380952 2.61050420168067 0.178450999958983 0.274735872469159 GO:0003925 G protein activity 1/68 54/18639 0.0185185185185185 5.07598039215686 0.179341472306256 0.274735872469159 GO:0015485 cholesterol binding 1/68 54/18639 0.0185185185185185 5.07598039215686 0.179341472306256 0.274735872469159 GO:0050661 NADP binding 1/68 54/18639 0.0185185185185185 5.07598039215686 0.179341472306256 0.274735872469159 GO:0051287 NAD binding 1/68 54/18639 0.0185185185185185 5.07598039215686 0.179341472306256 0.274735872469159 GO:0098632 cell-cell adhesion mediator activity 1/68 55/18639 0.0181818181818182 4.98368983957219 0.18234415080414 0.277857753606309 GO:0170055 lipid transmembrane transporter activity 1/68 56/18639 0.0178571428571429 4.89469537815126 0.185336003889876 0.280930363790971 GO:0004601 peroxidase activity 1/68 57/18639 0.0175438596491228 4.80882352941176 0.188317070011358 0.283954534886236 GO:0001786 phosphatidylserine binding 1/68 59/18639 0.0169491525423729 4.64581256231306 0.194246994481138 0.288286434353961 GO:0004879 nuclear receptor activity 1/68 59/18639 0.0169491525423729 4.64581256231306 0.194246994481138 0.288286434353961 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/68 59/18639 0.0169491525423729 4.64581256231306 0.194246994481138 0.288286434353961 GO:0001098 basal transcription machinery binding 1/68 60/18639 0.0166666666666667 4.56838235294118 0.197195929054619 0.288286434353961 GO:0001099 basal RNA polymerase II transcription machinery binding 1/68 60/18639 0.0166666666666667 4.56838235294118 0.197195929054619 0.288286434353961 GO:0098531 ligand-modulated transcription factor activity 1/68 60/18639 0.0166666666666667 4.56838235294118 0.197195929054619 0.288286434353961 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/68 61/18639 0.0163934426229508 4.49349083895853 0.200134229115133 0.289641497412856 GO:0016836 hydro-lyase activity 1/68 61/18639 0.0163934426229508 4.49349083895853 0.200134229115133 0.289641497412856 GO:0038024 cargo receptor activity 1/68 65/18639 0.0153846153846154 4.21696832579186 0.21178183784848 0.303448603484389 GO:0120013 lipid transfer activity 1/68 65/18639 0.0153846153846154 4.21696832579186 0.21178183784848 0.303448603484389 GO:0050840 extracellular matrix binding 1/68 67/18639 0.0149253731343284 4.09108867427568 0.217542811161084 0.310160047596001 GO:0032934 sterol binding 1/68 68/18639 0.0147058823529412 4.03092560553633 0.220407720101481 0.312696666942002 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/68 70/18639 0.0142857142857143 3.91575630252101 0.226106566872065 0.317652152483682 GO:0097110 scaffold protein binding 1/68 70/18639 0.0142857142857143 3.91575630252101 0.226106566872065 0.317652152483682 GO:0042379 chemokine receptor binding 1/68 72/18639 0.0138888888888889 3.80698529411765 0.231764363087842 0.324020080433487 GO:0043539 protein serine/threonine kinase activator activity 1/68 73/18639 0.0136986301369863 3.75483481063658 0.234577958354176 0.326369333362332 GO:0031491 nucleosome binding 1/68 74/18639 0.0135135135135135 3.70409379968204 0.237381400066549 0.327821424666482 GO:0003713 transcription coactivator activity 2/68 256/18639 0.0078125 2.14142922794118 0.239734215104323 0.327821424666482 GO:0003725 double-stranded RNA binding 1/68 75/18639 0.0133333333333333 3.65470588235294 0.240174724321624 0.327821424666482 GO:0019003 GDP binding 1/68 75/18639 0.0133333333333333 3.65470588235294 0.240174724321624 0.327821424666482 GO:0017022 myosin binding 1/68 76/18639 0.0131578947368421 3.60661764705882 0.242957967089677 0.330056106235032 GO:0016835 carbon-oxygen lyase activity 1/68 79/18639 0.0126582278481013 3.46965748324646 0.251247564287754 0.339715016501752 GO:0001540 amyloid-beta binding 1/68 83/18639 0.0120481927710843 3.30244507441531 0.262161379991465 0.3528153151287 GO:0051117 ATPase binding 1/68 84/18639 0.0119047619047619 3.26313025210084 0.264865250769681 0.35479624289148 GO:0008017 microtubule binding 2/68 276/18639 0.0072463768115942 1.98625319693095 0.266793723255936 0.355724964341248 GO:0003712 transcription coregulator activity 3/68 495/18639 0.00606060606060606 1.66122994652406 0.270124430768725 0.357019248807171 GO:0016209 antioxidant activity 1/68 86/18639 0.0116279069767442 3.18724350205198 0.270243736944317 0.357019248807171 GO:0005543 phospholipid binding 3/68 497/18639 0.00603621730382294 1.65454491655817 0.272106896021215 0.357839205726529 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/68 91/18639 0.010989010989011 3.01212023270847 0.283520908231703 0.369475210727287 GO:0072341 modified amino acid binding 1/68 91/18639 0.010989010989011 3.01212023270847 0.283520908231703 0.369475210727287 GO:0043178 alcohol binding 1/68 92/18639 0.0108695652173913 2.97937979539642 0.286147637703358 0.371218557020572 GO:0042562 hormone binding 1/68 94/18639 0.0106382978723404 2.9159887359199 0.291372663675201 0.376301915419094 GO:0004896 cytokine receptor activity 1/68 96/18639 0.0104166666666667 2.85523897058824 0.296560003549543 0.381291433135126 GO:0030594 neurotransmitter receptor activity 1/68 97/18639 0.0103092783505155 2.8258035172832 0.299139624957009 0.382898719944971 GO:0043130 ubiquitin binding 1/68 100/18639 0.01 2.74102941176471 0.306822694280267 0.390995291826181 GO:0043022 ribosome binding 1/68 112/18639 0.00892857142857143 2.44734768907563 0.33673376715232 0.427221695770344 GO:0001221 transcription coregulator binding 1/68 115/18639 0.00869565217391304 2.38350383631714 0.344010582184039 0.434539682758786 GO:0140097 catalytic activity, acting on DNA 2/68 336/18639 0.00595238095238095 1.63156512605042 0.347554828959819 0.437099522883965 GO:0032182 ubiquitin-like protein binding 1/68 120/18639 0.00833333333333333 2.28419117647059 0.355964190501567 0.445729073323701 GO:0003697 single-stranded DNA binding 1/68 121/18639 0.00826446280991736 2.26531356344191 0.358329028508257 0.446747879698606 GO:0141003 histone H2AX kinase activity 2/68 354/18639 0.00564971751412429 1.54860418743769 0.371323672264956 0.459729716216322 GO:0042826 histone deacetylase binding 1/68 127/18639 0.0078740157480315 2.15829087540528 0.37233943950682 0.459729716216322 GO:0031490 chromatin DNA binding 1/68 128/18639 0.0078125 2.14142922794118 0.374645020649513 0.459729716216322 GO:0140996 histone H3 kinase activity 2/68 357/18639 0.00560224089635854 1.53559070687098 0.375254248113399 0.459729716216322 GO:0035173 histone kinase activity 2/68 360/18639 0.00555555555555556 1.52279411764706 0.379175265957387 0.459729716216322 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/68 130/18639 0.00769230769230769 2.10848416289593 0.379231177748189 0.459729716216322 GO:0005262 calcium channel activity 1/68 131/18639 0.00763358778625954 2.09238886394252 0.381511813110073 0.459729716216322 GO:0031072 heat shock protein binding 1/68 131/18639 0.00763358778625954 2.09238886394252 0.381511813110073 0.459729716216322 GO:0099094 ligand-gated monoatomic cation channel activity 1/68 136/18639 0.00735294117647059 2.01546280276817 0.392791736803936 0.471350084164723 GO:0016922 nuclear receptor binding 1/68 137/18639 0.0072992700729927 2.00075139544869 0.395023275575883 0.472061009816822 GO:0030295 protein kinase activator activity 1/68 139/18639 0.00719424460431655 1.97196360558612 0.39946213920107 0.475392959049207 GO:0022843 voltage-gated monoatomic cation channel activity 1/68 143/18639 0.00699300699300699 1.91680378445084 0.408243814413246 0.483844520786069 GO:0019955 cytokine binding 1/68 144/18639 0.00694444444444444 1.90349264705882 0.410419388624962 0.48442944231143 GO:0015085 calcium ion transmembrane transporter activity 1/68 147/18639 0.00680272108843537 1.86464585834334 0.416898936245105 0.490068953626899 GO:0019209 kinase activator activity 1/68 148/18639 0.00675675675675676 1.85204689984102 0.419043153870853 0.490587106970755 GO:0019842 vitamin binding 1/68 150/18639 0.00666666666666667 1.82735294117647 0.423308308881172 0.493574060557803 GO:0005178 integrin binding 1/68 161/18639 0.0062111801242236 1.70250274022653 0.446220972205688 0.518192096754992 GO:0008083 growth factor activity 1/68 162/18639 0.00617283950617284 1.69199346405229 0.448258907798826 0.518468134321534 GO:0016874 ligase activity 1/68 167/18639 0.00598802395209581 1.64133497710461 0.45833826504756 0.528005681334789 GO:0008201 heparin binding 1/68 172/18639 0.00581395348837209 1.59362175102599 0.468236148844882 0.536201663753698 GO:0005244 voltage-gated monoatomic ion channel activity 1/68 173/18639 0.00578034682080925 1.58441006460388 0.470194233096712 0.536201663753698 GO:0004674 protein serine/threonine kinase activity 2/68 433/18639 0.0046189376443418 1.26606439342481 0.471038267116964 0.536201663753698 GO:0022832 voltage-gated channel activity 1/68 175/18639 0.00571428571428571 1.5663025210084 0.474089113502657 0.53754986097939 GO:0043021 ribonucleoprotein complex binding 1/68 177/18639 0.00564971751412429 1.54860418743769 0.477955778623754 0.539808879386828 GO:0015276 ligand-gated monoatomic ion channel activity 1/68 186/18639 0.00537634408602151 1.47367172675522 0.495011973608781 0.556623300451965 GO:0022834 ligand-gated channel activity 1/68 188/18639 0.00531914893617021 1.45799436795995 0.498727016395272 0.556623300451965 GO:0046943 carboxylic acid transmembrane transporter activity 1/68 188/18639 0.00531914893617021 1.45799436795995 0.498727016395272 0.556623300451965 GO:0005342 organic acid transmembrane transporter activity 1/68 189/18639 0.00529100529100529 1.45028011204482 0.500574426448121 0.556623300451965 GO:0003714 transcription corepressor activity 1/68 204/18639 0.00490196078431373 1.34364186851211 0.527493814425964 0.584300840594914 GO:0005516 calmodulin binding 1/68 207/18639 0.00483091787439614 1.32416879795396 0.532703542521772 0.587810805541265 GO:0005539 glycosaminoglycan binding 1/68 242/18639 0.00413223140495868 1.13265678172095 0.5894563929992 0.647952065586907 GO:0035402 histone H3T11 kinase activity 1/68 247/18639 0.00404858299595142 1.10972850678733 0.596988692032099 0.651260391307745 GO:0042393 histone binding 1/68 247/18639 0.00404858299595142 1.10972850678733 0.596988692032099 0.651260391307745 GO:0019887 protein kinase regulator activity 1/68 255/18639 0.00392156862745098 1.07491349480969 0.608758084494398 0.661593691827874 GO:0016757 glycosyltransferase activity 1/68 267/18639 0.00374531835205993 1.02660277594184 0.625779936834659 0.675451424103111 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/68 268/18639 0.00373134328358209 1.02277216856892 0.627165031777793 0.675451424103111 GO:0008514 organic anion transmembrane transporter activity 1/68 269/18639 0.00371747211895911 1.01897004154822 0.628545075207062 0.675451424103111 GO:0016791 phosphatase activity 1/68 273/18639 0.00366300366300366 1.00404007756949 0.634015095806546 0.676662127557075 GO:0005126 cytokine receptor binding 1/68 275/18639 0.00363636363636364 0.996737967914439 0.636720265860998 0.676662127557075 GO:1901681 sulfur compound binding 1/68 275/18639 0.00363636363636364 0.996737967914439 0.636720265860998 0.676662127557075 GO:0001217 DNA-binding transcription repressor activity 1/68 278/18639 0.00359712230215827 0.98598180279306 0.640741121466388 0.678431775670293 GO:0031267 small GTPase binding 1/68 283/18639 0.00353356890459364 0.968561629598836 0.647345321873225 0.682913746151974 GO:0019207 kinase regulator activity 1/68 287/18639 0.00348432055749129 0.955062512810002 0.652542430379998 0.685884014414013 GO:0022836 gated channel activity 1/68 318/18639 0.00314465408805031 0.861958934517203 0.690341517871048 0.722975844170407 GO:0003924 GTPase activity 1/68 331/18639 0.00302114803625378 0.828105562466679 0.704959172513292 0.735609571318218 GO:0005261 monoatomic cation channel activity 1/68 341/18639 0.00293255131964809 0.803820941866483 0.715738895731942 0.744161739966785 GO:0042578 phosphoric ester hydrolase activity 1/68 363/18639 0.00275482093663912 0.755104521147302 0.738106951824176 0.764657561602024 GO:0046982 protein heterodimerization activity 1/68 369/18639 0.002710027100271 0.742826398852224 0.743900216711696 0.767896997895944 GO:0005525 GTP binding 1/68 378/18639 0.00264550264550265 0.725140056022409 0.752354137136198 0.773849969625804 GO:0019001 guanyl nucleotide binding 1/68 400/18639 0.0025 0.685257352941177 0.771878975283595 0.788301932204523 GO:0032561 guanyl ribonucleotide binding 1/68 400/18639 0.0025 0.685257352941177 0.771878975283595 0.788301932204523 GO:0004175 endopeptidase activity 1/68 405/18639 0.00246913580246914 0.676797385620915 0.776100332940211 0.789812352956823 GO:0005216 monoatomic ion channel activity 1/68 448/18639 0.00223214285714286 0.611836922268908 0.809366479677408 0.816458927552539 GO:0004842 ubiquitin-protein transferase activity 1/68 449/18639 0.0022271714922049 0.610474256517752 0.810079089175618 0.816458927552539 GO:0046873 metal ion transmembrane transporter activity 1/68 450/18639 0.00222222222222222 0.609117647058824 0.81078907388898 0.816458927552539 GO:0019787 ubiquitin-like protein transferase activity 1/68 479/18639 0.00208768267223382 0.572239960702444 0.830278609538729 0.83317156636639 GO:0016755 aminoacyltransferase activity 1/68 496/18639 0.00201612903225806 0.552626897533207 0.840769286062508 0.840769286062508