category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/39	88/9376	8.19580419580419	C4BPA/CD55/CLU	4.38302383451145
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	3/39	89/9376	8.10371650821089	COMP/LAMB3/ITGB3	4.3516821268258
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	3/39	103/9376	7.00224047796863	SLC1A1/SLC15A1/DPP4	3.95855001140744
NA	NA	hsa04081	Hormone signaling	4/39	219/9376	4.39105491160286	GAST/ITGB3/SLC40A1/ADRA2A	3.28166719016508
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/39	42/9376	11.4481074481074	CP/SLC40A1	4.38573755267497
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/39	45/9376	10.6849002849003	DEFB1/ABCC3	4.20873496634893
NA	NA	hsa03272	Virion - Hepatitis viruses	2/39	48/9376	10.017094017094	CLDN10/DPP4	4.04768968625695
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	3/39	144/9376	5.00854700854701	LIF/INHBB/ID4	3.13281385938339
NA	NA	hsa04518	Integrin signaling	3/39	154/9376	4.68331668331668	COMP/LAMB3/ITGB3	2.97852413755792
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	2/39	79/9376	6.08633560532295	SLC1A1/STX1A	2.93400875053164
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/39	203/9376	3.55286093217128	COMP/LAMB3/ITGB3	2.3764776904582
NA	NA	hsa04382	Cornified envelope formation	3/39	217/9376	3.32364409783765	CLDN10/KRT7/LAMB3	2.23815268071064
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	4/39	362/9376	2.65646692166029	COMP/TGFA/LAMB3/ITGB3	2.07726803624107
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/39	100/9376	4.80820512820513	CD55/ITGB3	2.4743106580538
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/39	110/9376	4.37109557109557	INHBB/ID4	2.29845244153614
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/39	22/9376	10.9277389277389	AOC1	3.01284831923055
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/39	30/9376	8.01367521367521	ABCC3	2.48660986465192
NA	NA	hsa04981	Folate transport and metabolism	1/39	31/9376	7.75516956162117	ABCC3	2.43467900719265
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	3/39	298/9376	2.42023748064016	CXCL14/LIF/INHBB	1.61023133901649
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/39	33/9376	7.28515928515929	STX1A	2.33746085379466
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	3/39	308/9376	2.34165834165834	GPX3/STX1A/SOD2	1.54730454072836
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/39	155/9376	3.10206782464847	COMP/ITGB3	1.70544542011723
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/39	38/9376	6.32658569500675	NNMT	2.12631716074797
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/39	166/9376	2.89650911337658	EDNRB/ADRA2A	1.59328484489355
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/39	333/9376	2.16585816585817	COMP/LAMB3/ITGB3	1.39999289801292
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/39	42/9376	5.72405372405372	AOC1	1.98298686353856
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/39	46/9376	5.2263099219621	CP	1.85700767063844
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/39	49/9376	4.90633176347462	ST6GAL1	1.77178262700373
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/39	50/9376	4.80820512820513	AOC1	1.74490542320874
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/39	50/9376	4.80820512820513	COMP	1.74490542320874
NA	NA	hsa04082	Neuroactive ligand signaling	2/39	199/9376	2.41618348151011	SLC1A1/ADRA2A	1.30499833956475
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/39	56/9376	4.29304029304029	ST6GAL1	1.59733998929391
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/39	59/9376	4.07475010864841	CDA	1.53112992964887
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/39	59/9376	4.07475010864841	GPX3	1.53112992964887
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/39	61/9376	3.94115174443043	SLC40A1	1.48937884912047
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/39	62/9376	3.87758478081059	SOD2	1.46916345934552
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/39	68/9376	3.53544494720965	DHRS3	1.35610936896128
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/39	69/9376	3.4842066146414	STX1A	1.33851013687207
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/39	233/9376	2.063607351161	COMP/ITGB3	1.06250062270323
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/39	70/9376	3.43443223443223	TGFA	1.32123310871653
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/39	70/9376	3.43443223443223	CD55	1.32123310871653
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/39	73/9376	3.29329118370214	TGFA	1.27122780475359
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/39	75/9376	3.20547008547009	GPX3	1.23931367905581
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/39	76/9376	3.16329284750337	GAST	1.22375618150182
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/39	76/9376	3.16329284750337	TGFA	1.22375618150182
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/39	77/9376	3.12221112221112	TGFA	1.20845389914154
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/39	78/9376	3.08218277449047	C4BPA	1.19339892431173
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/39	250/9376	1.92328205128205	SLC15A4/CD68	0.956265367187193
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/39	80/9376	3.00512820512821	TGFA	1.16400097560193
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/39	254/9376	1.89299414496265	TGFA/EDNRB	0.932469634433743
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/39	82/9376	2.93183239524703	CDA	1.13550564864167
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/39	83/9376	2.89650911337658	SOD2	1.12158004530386
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/39	85/9376	2.82835595776772	CDA	1.09434245096996
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/39	86/9376	2.79546809779368	TGFA	1.08101899167904
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/39	86/9376	2.79546809779368	STX1A	1.08101899167904
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/39	86/9376	2.79546809779368	ITGB3	1.08101899167904
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/39	87/9376	2.76333628057766	TGFA	1.06788515766661
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/39	90/9376	2.67122507122507	SOD2	1.02957056919661
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/39	90/9376	2.67122507122507	ABCC3	1.02957056919661
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/39	93/9376	2.58505652054039	LAMB3	0.992787532050078
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/39	99/9376	2.42838642838643	TRPM8	0.923365824504619
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/39	99/9376	2.42838642838643	DEFB1	0.923365824504619
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/39	99/9376	2.42838642838643	ITGB3	0.923365824504619
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/39	100/9376	2.40410256410256	CXCL14	0.912289601636319
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/39	101/9376	2.38029956841838	EDNRB	0.901345598388878
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/39	103/9376	2.33408015932288	LAMB3	0.879841960562917
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/39	105/9376	2.28962148962149	ITGB3	0.858831337251681
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/39	106/9376	2.26802128688921	TGFA	0.848503957385859
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/39	112/9376	2.14652014652015	LAMB3	0.788870454843714
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/39	116/9376	2.07250221043325	CLDN10	0.75116606447365
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/39	116/9376	2.07250221043325	SLC1A1	0.75116606447365
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/39	119/9376	2.02025425554837	LIF	0.723870746580553
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/39	122/9376	1.97057587221522	ITGB3	0.69736303157394
Organismal Systems	Immune system	hsa04611	Platelet activation	1/39	126/9376	1.90801790801791	ITGB3	0.663167267601572
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/39	130/9376	1.84930966469428	EDNRB	0.630195155163228
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/39	133/9376	1.80759591285907	SOD2	0.606216452294071
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/39	139/9376	1.72957019000184	TGFA	0.56004544735918
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/39	142/9376	1.69302997472012	ITGB3	0.53779346227051
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/39	142/9376	1.69302997472012	ITGB3	0.53779346227051
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/39	144/9376	1.66951566951567	KCND3	0.52324893884513
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/39	370/9376	1.2995148995149	EDNRB/ADRA2A	0.379898504989315
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/39	154/9376	1.56110556110556	DHRS3	0.453739550834924
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/39	156/9376	1.54109138724523	CLDN10	0.440434896979912
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/39	157/9376	1.53127551853667	ITGB3	0.433852380652139
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/39	160/9376	1.5025641025641	CLDN10	0.414375896103514
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/39	168/9376	1.43101343101343	LIF	0.364314998827837
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/39	170/9376	1.41417797888386	CLDN10	0.352200722238523
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/39	170/9376	1.41417797888386	TGFA	0.352200722238523
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/39	180/9376	1.33561253561254	ITGB3	0.29382531305912
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/39	184/9376	1.30657748049052	ABLIM3	0.271430356287127
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/39	193/9376	1.24564899694433	CXCL14	0.222851529832619
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/39	194/9376	1.23922812582606	KIF12	0.217599914795798
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/39	195/9376	1.23287310979619	ITGB3	0.212376234864754
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/39	200/9376	1.20205128205128	CLDN10	0.186665547374274
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	1/39	204/9376	1.17848164906988	ITGB3	0.166567739875299
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/39	212/9376	1.13401064344461	ITGB3	0.127549554174163
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/39	216/9376	1.11301044634378	SOD2	0.108595540509671
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	2/39	480/9376	1.0017094017094	GPX3/STX1A	0.00248474386971255
Genetic Information Processing	Translation	hsa03010	Ribosome	1/39	222/9376	1.08292908292908	RPL39	0.0808150336787027
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/39	227/9376	1.05907601942844	ITGB3	0.0582306451471415
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/39	227/9376	1.05907601942844	SOD2	0.0582306451471415
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/39	232/9376	1.03625110521662	ITGB3	0.0361336137497161
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/39	238/9376	1.01012712777419	TGFA	0.0102273578862533
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/39	238/9376	1.01012712777419	RPL39	0.0102273578862533
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/39	248/9376	0.969396195202647	ANXA2	-0.0315665929598913
NA	NA	hsa04517	IgSF CAM signaling	1/39	299/9376	0.804047680301861	ITGB3	-0.222550768244469
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/39	300/9376	0.801367521367521	TGFA	-0.225984112649113
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/39	323/9376	0.744304199412559	ITGB3	-0.302233679721011
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/39	368/9376	0.653288740245262	GPX3	-0.438522547998539
NA	NA	hsa04519	Cadherin signaling	1/39	404/9376	0.595074892104595	KRT7	-0.537693787889512