category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	5/24	110/9376	17.7575757575758	GAPDH/LDHA/ALDOA/RPS6/TIMP1	8.95571771351932
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	4/24	67/9376	23.3233830845771	GAPDH/LDHA/PKM/ALDOA	9.28934105808334
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/24	238/9376	8.20728291316527	RPS3A/FOS/RPS27A/RPL29/RPS6	5.7052342634028
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	3/24	75/9376	15.6266666666667	GAPDH/PKM/ALDOA	6.44243704973027
Genetic Information Processing	Translation	hsa03010	Ribosome	4/24	222/9376	7.03903903903904	RPS3A/RPS27A/RPL29/RPS6	4.61294079051002
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	3/24	116/9376	10.1034482758621	GAPDH/PKM/ALDOA	4.9976799458124
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/24	119/9376	9.84873949579832	SOCS3/FOS/JUNB	4.92106122833929
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/24	122/9376	9.60655737704918	SOCS3/FOS/JUNB	4.84711859884327
Human Diseases	Infectious disease: viral	hsa05162	Measles	3/24	136/9376	8.61764705882353	HSPA1A/FOS/HSPA1B	4.53307939479481
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/24	139/9376	8.43165467625899	HSPA1A/FOS/HSPA1B	4.47163616135512
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/24	142/9376	8.25352112676056	SOCS3/FOS/JUNB	4.4120164943619
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	2/24	47/9376	16.6241134751773	LDHA/PKM	5.43958511761954
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	2/24	47/9376	16.6241134751773	SOCS3/PKM	5.43958511761954
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/24	56/9376	13.952380952381	HSPA1A/HSPA1B	4.92464213538337
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/24	62/9376	12.6021505376344	HSPA1A/HSPA1B	4.64307003013477
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	3/24	196/9376	5.97959183673469	ZFP36/FOS/RPS27A	3.56894168123151
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/24	200/9376	5.86	GAPDH/FOS/ACTG1	3.51935903535019
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/24	71/9376	11.0046948356808	SOCS3/FOS	4.28660870810003
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/24	71/9376	11.0046948356808	LDHA/PKM	4.28660870810003
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	3/24	216/9376	5.42592592592593	HSPA1A/FOS/HSPA1B	3.33366756697777
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/24	82/9376	9.52845528455285	HSPA1A/HSPA1B	3.92929810561723
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/24	248/9376	4.7258064516129	GAPDH/FOS/ACTG1	3.0122937803124
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/24	107/9376	7.30218068535826	LDHA/PKM	3.32127860690037
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/24	110/9376	7.1030303030303	ID1/ID3	3.26163028481517
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/24	112/9376	6.97619047619048	HSPA1A/HSPA1B	3.22309554007534
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/24	300/9376	3.90666666666667	HSPA1A/FOS/HSPA1B	2.59207536131387
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/24	137/9376	5.70316301703163	FOS/ACTG1	2.80916236962856
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/24	138/9376	5.66183574879227	SOCS3/RPS6	2.79477302046725
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/24	138/9376	5.66183574879227	FOS/ACTG1	2.79477302046725
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/24	142/9376	5.50234741784038	SOCS3/RPS27A	2.7385914680214
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/24	142/9376	5.50234741784038	FOS/ACTG1	2.7385914680214
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/24	144/9376	5.42592592592593	ID1/ID3	2.71129328989742
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/24	154/9376	5.07359307359307	FOS/ACTG1	2.58204885314139
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/24	157/9376	4.97664543524416	ID1/ACTG1	2.5454454768893
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/24	157/9376	4.97664543524416	SOCS3/FOS	2.5454454768893
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/24	173/9376	4.51637764932563	SOCS3/ACTG1	2.36479153149077
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/24	174/9376	4.4904214559387	HSPA1A/HSPA1B	2.35423812942143
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/24	31/9376	12.6021505376344	ALDOA	3.2776962191932
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/24	32/9376	12.2083333333333	LDHA	3.21727824676002
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/24	35/9376	11.1619047619048	ALDOA	3.05106504568028
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/24	38/9376	10.280701754386	NNMT	2.90392028099813
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/24	204/9376	3.83006535947712	RPS6/ACTG1	2.07022970674073
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/24	212/9376	3.68553459119497	ID1/ACTG1	2.00352677591655
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/24	224/9376	3.48809523809524	ZFP36/FOS	1.90929050797544
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	2/24	235/9376	3.32482269503546	RPS6/ACTG1	1.8283777315375
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/24	50/9376	7.81333333333333	ACKR1	2.44701112226212
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/24	51/9376	7.66013071895425	ACTG1	2.41591934289937
Genetic Information Processing	Transcription	hsa03040	Spliceosome	2/24	243/9376	3.21536351165981	HSPA1A/HSPA1B	1.7724762159848
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/24	54/9376	7.23456790123457	LDHA	2.32748933604077
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/24	250/9376	3.12533333333333	HSPA1A/HSPA1B	1.72542400456024
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/24	253/9376	3.08827404479578	RPS27A/ACTG1	1.70575999130757
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	2/24	275/9376	2.84121212121212	HSPA1A/HSPA1B	1.56987337905289
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/24	69/9376	5.66183574879227	FOS	1.96886376495589
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/24	70/9376	5.58095238095238	SOCS3	1.9487776186565
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/24	70/9376	5.58095238095238	ACTG1	1.9487776186565
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/24	76/9376	5.14035087719298	ACTG1	1.83586811491068
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/24	78/9376	5.00854700854701	ACTG1	1.80085406852609
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/24	78/9376	5.00854700854701	FOS	1.80085406852609
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/24	78/9376	5.00854700854701	FOS	1.80085406852609
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/24	80/9376	4.88333333333333	RPS6	1.76701654770464
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/24	86/9376	4.54263565891473	ACTG1	1.67188679791251
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/24	87/9376	4.4904214559387	FOS	1.65688369617594
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/24	88/9376	4.43939393939394	CD59	1.6421059107609
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/24	90/9376	4.34074074074074	FOS	1.61320180184813
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/24	91/9376	4.29304029304029	FOS	1.59906381867021
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/24	93/9376	4.20071684587814	ACTG1	1.57138847883527
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/24	93/9376	4.20071684587814	FOS	1.57138847883527
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/24	93/9376	4.20071684587814	CST3	1.57138847883527
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/24	94/9376	4.15602836879433	FOS	1.55784072537511
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/24	95/9376	4.11228070175439	FOS	1.54447963464196
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/24	97/9376	4.02749140893471	FOS	1.51829866154491
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/24	99/9376	3.94612794612795	FOS	1.49280964605985
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/24	99/9376	3.94612794612795	FOS	1.49280964605985
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/24	99/9376	3.94612794612795	ACTG1	1.49280964605985
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/24	100/9376	3.90666666666667	CD59	1.48031408088652
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/24	103/9376	3.79288025889968	FOS	1.44377596843024
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/24	105/9376	3.72063492063492	RPS27A	1.42017099029537
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/24	105/9376	3.72063492063492	ACTG1	1.42017099029537
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/24	109/9376	3.58409785932722	FOS	1.37464840889396
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/24	109/9376	3.58409785932722	FOS	1.37464840889396
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/24	109/9376	3.58409785932722	SOCS3	1.37464840889396
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/24	115/9376	3.39710144927536	FOS	1.31022355405774
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/24	115/9376	3.39710144927536	FOS	1.31022355405774
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/24	116/9376	3.36781609195402	ACTG1	1.29990160206737
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/24	117/9376	3.33903133903134	ACTG1	1.28969180268064
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/24	122/9376	3.20218579234973	FOS	1.24024685418022
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/24	122/9376	3.20218579234973	ACTG1	1.24024685418022
Organismal Systems	Immune system	hsa04611	Platelet activation	1/24	126/9376	3.1005291005291	ACTG1	1.20249178679624
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/24	130/9376	3.00512820512821	FOS	1.16620765447997
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/24	133/9376	2.93734335839599	FOS	1.13989527162798
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/24	140/9376	2.79047619047619	RPS6	1.08125870246836
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/24	148/9376	2.63963963963964	FOS	1.0185080923531
NA	NA	hsa04518	Integrin signaling	1/24	154/9376	2.53679653679654	ACTG1	0.974099195393406
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/24	155/9376	2.52043010752688	ACTG1	0.966901666945962
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/24	156/9376	2.5042735042735	SOCS3	0.959760019562438
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/24	158/9376	2.47257383966245	RPS6	0.945640975899488
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/24	163/9376	2.39672801635992	FOS	0.911263806108362
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/24	168/9376	2.32539682539683	SOCS3	0.878126172687019
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/24	169/9376	2.31163708086785	RPS27A	0.87163964807806
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/24	170/9376	2.29803921568627	ACTG1	0.865198581484768
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/24	170/9376	2.29803921568627	ACTG1	0.865198581484768
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/24	180/9376	2.17037037037037	SOCS3	0.803154504951497
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/24	194/9376	2.01374570446735	ACTG1	0.722770232511892
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/24	195/9376	2.0034188034188	ACTG1	0.717287986525889
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/24	203/9376	1.92446633825944	ACTG1	0.674562872769923
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/24	205/9376	1.90569105691057	PKM	0.664182874134183
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/24	205/9376	1.90569105691057	GAPDH	0.664182874134183
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/24	214/9376	1.82554517133956	FOS	0.618858833625242
NA	NA	hsa04382	Cornified envelope formation	1/24	217/9376	1.80030721966206	S100A6	0.604229023238884
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/24	217/9376	1.80030721966206	FOS	0.604229023238884
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/24	226/9376	1.72861356932153	FOS	0.561668331241315
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/24	227/9376	1.72099853157122	FOS	0.557056832003947
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/24	232/9376	1.68390804597701	ACTG1	0.534333750675002
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/24	233/9376	1.67668097281831	ACTG1	0.529854437161239
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/24	250/9376	1.56266666666667	LAPTM4B	0.456793557041669
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/24	268/9376	1.45771144278607	RPS27A	0.385111658244135
NA	NA	hsa04517	IgSF CAM signaling	1/24	299/9376	1.30657748049052	ACTG1	0.272925231405819
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	1/24	333/9376	1.17317317317317	PKM	0.162999201246848
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/24	362/9376	1.07918968692449	RPS6	0.0778400568363702
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/24	368/9376	1.06159420289855	ACTG1	0.0610644668810745
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/24	388/9376	1.00687285223368	GAPDH	0.00700422917549315
NA	NA	hsa04519	Cadherin signaling	1/24	404/9376	0.966996699669967	ACTG1	-0.0343512410184038
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	1/24	480/9376	0.813888888888889	RPS27A	-0.212048177167819