category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/23	139/9376	8.79824835783547	FOS/KRT19/KRT23	4.59317592472957
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	4/23	300/9376	5.43536231884058	FLT1/FOS/DUSP1/GADD45G	3.87183262827432
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/23	71/9376	11.4831598285364	CGA/FOS	4.39680577892716
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/23	87/9376	9.37131434282858	FOS/GADD45G	3.88993983208379
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/23	91/9376	8.95938843764931	FOS/PIK3AP1	3.78341107685012
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/23	93/9376	8.76671341748481	FOS/STAT4	3.73257608000982
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/23	95/9376	8.58215102974828	FLT1/FOS	3.68324778442524
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/23	99/9376	8.23539745278876	KRT19/KRT23	3.58880863082469
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/23	109/9376	7.47985640207419	FOS/EBI3	3.37429569786318
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/23	110/9376	7.41185770750988	LRRC32/GREM2	3.35434832958541
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/23	119/9376	6.85129704055535	FOS/JUNB	3.18540445751108
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/23	122/9376	6.68282252316465	FOS/JUNB	3.13294917760599
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/23	137/9376	5.95112662646779	FOS/GADD45G	2.89484905055935
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/23	142/9376	5.74157991426822	FOS/JUNB	2.82323091271606
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/23	142/9376	5.74157991426822	FOS/DUSP1	2.82323091271606
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/23	148/9376	5.50881316098707	FOS/GADD45G	2.74165871883901
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/23	157/9376	5.19302132373304	LEP/FOS	2.62729644863738
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/23	163/9376	5.00186716457722	FOS/STAT4	2.55581858884611
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	3/23	370/9376	3.30528789659224	CGA/LEP/ADM	2.24354171979132
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/23	168/9376	4.85300207039337	LEP/STAT4	2.49887951562934
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/23	201/9376	4.05624053644819	FLT1/GADD45G	2.17198395645235
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/23	37/9376	11.0176263219741	GADD45G	3.02753791685056
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/23	42/9376	9.70600414078675	SAT1	2.80403677648323
NA	NA	hsa04382	Cornified envelope formation	2/23	217/9376	3.75716289320777	KRT19/KRT23	2.03770988125155
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/23	217/9376	3.75716289320777	FOS/PAQR7	2.03770988125155
NA	NA	hsa04081	Hormone signaling	2/23	219/9376	3.72285090331547	CGA/LEP	2.02182424639835
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/23	44/9376	9.26482213438735	MAN1C1	2.72487493392927
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/23	226/9376	3.60754136206233	CGA/FOS	1.96765506449633
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/23	50/9376	8.15304347826087	SAT1	2.51479304433147
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/23	52/9376	7.83946488294314	CGA	2.45243074730321
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	2/23	248/9376	3.2875175315568	FOS/SNX9	1.81040835383429
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/23	54/9376	7.54911433172303	CGA	2.39331020083526
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/23	56/9376	7.27950310559006	MAN1C1	2.33714375369693
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/23	59/9376	6.90935887988209	PRDX6	2.25788809096199
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/23	59/9376	6.90935887988209	CGA	2.25788809096199
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/23	59/9376	6.90935887988209	GADD45G	2.25788809096199
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/23	63/9376	6.47066942719117	GADD45G	2.16042918262411
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/23	65/9376	6.27157190635451	CGA	2.11481673726988
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/23	66/9376	6.17654808959157	STAT4	2.09272165943698
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/23	69/9376	5.90800252047889	FOS	2.02907712359795
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/23	70/9376	5.82360248447205	LEP	2.00869082155502
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/23	73/9376	5.5842763549732	GADD45G	1.94982124923168
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/23	73/9376	5.5842763549732	GADD45G	1.94982124923168
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/23	298/9376	2.73592063028888	LEP/EBI3	1.51013925318094
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/23	75/9376	5.43536231884058	GADD45G	1.91235713749599
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/23	75/9376	5.43536231884058	CGA	1.91235713749599
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/23	76/9376	5.36384439359268	PLIN2	1.89412513404673
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/23	76/9376	5.36384439359268	GADD45G	1.89412513404673
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/23	77/9376	5.29418407679277	GADD45G	1.87621232677805
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/23	77/9376	5.29418407679277	GADD45G	1.87621232677805
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/23	78/9376	5.2263099219621	FOS	1.85860867912947
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/23	78/9376	5.2263099219621	FOS	1.85860867912947
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/23	90/9376	4.52946859903382	FOS	1.66836214242637
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/23	93/9376	4.3833567087424	CGA	1.62599488900446
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/23	93/9376	4.3833567087424	GADD45G	1.62599488900446
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/23	94/9376	4.33672525439408	FOS	1.61226966272917
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/23	97/9376	4.2025997310623	FOS	1.5722153483561
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/23	99/9376	4.11769872639438	FOS	1.54640075691803
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/23	99/9376	4.11769872639438	FOS	1.54640075691803
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	2/23	362/9376	2.25222195532068	FLT1/PIK3AP1	1.2048997422481
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/23	103/9376	3.95778809624314	FOS	1.49675124570024
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/23	105/9376	3.8824016563147	GADD45G	1.47285484159376
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/23	109/9376	3.7399282010371	FOS	1.42677975676345
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/23	110/9376	3.70592885375494	FLT1	1.4156003368476
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/23	115/9376	3.54480151228733	FOS	1.36159510457266
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/23	115/9376	3.54480151228733	DUSP1	1.36159510457266
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/23	115/9376	3.54480151228733	FOS	1.36159510457266
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/23	122/9376	3.34141126158232	LEP	1.29082378633334
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/23	122/9376	3.34141126158232	FOS	1.29082378633334
NA	NA	hsa04519	Cadherin signaling	2/23	404/9376	2.01808006887645	KRT19/KRT23	1.03729449820351
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/23	130/9376	3.13578595317726	FOS	1.2159803209823
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/23	133/9376	3.06505393919582	GADD45G	1.18939150664688
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/23	133/9376	3.06505393919582	FOS	1.18939150664688
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/23	134/9376	3.04218040233614	ADM	1.18069469068778
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/23	136/9376	2.99744245524297	FOS	1.16354138272038
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/23	138/9376	2.95400126023945	FOS	1.14669915575602
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/23	142/9376	2.87078995713411	RHOBTB1	1.11390551961095
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/23	150/9376	2.71768115942029	GADD45G	1.05161202973172
NA	NA	hsa04518	Integrin signaling	1/23	154/9376	2.64709203839639	FLT1	1.02197379144598
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/23	154/9376	2.64709203839639	FOS	1.02197379144598
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/23	157/9376	2.59651066186652	GADD45G	1.00035427160653
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/23	158/9376	2.58007705008255	GADD45G	0.993259084357874
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/23	168/9376	2.42650103519669	STAT4	0.925162808311992
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/23	170/9376	2.39795396419437	GADD45G	0.912128308199548
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/23	174/9376	2.34282858570715	MAN1C1	0.886600917737073
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/23	194/9376	2.10129986553115	KIF2A	0.768620380647449
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/23	196/9376	2.07985803016859	FOS	0.757613049039487
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/23	200/9376	2.03826086956522	FOS	0.735984843623075
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/23	203/9376	2.00813878774898	FLT1	0.720089926656505
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/23	205/9376	1.98854718981972	GADD45G	0.709643254098021
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/23	212/9376	1.92288761279737	FLT1	0.673981996988021
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/23	214/9376	1.90491670052824	FOS	0.664040297275343
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/23	216/9376	1.88727858293076	FOS	0.654204047071588
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/23	224/9376	1.81987577639752	FOS	0.615868721189001
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/23	227/9376	1.79582455468301	FOS	0.60189056942941
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/23	238/9376	1.71282426013884	FLT1	0.552356491911
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/23	238/9376	1.71282426013884	FOS	0.552356491911
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/23	254/9376	1.60492981855529	FLT1	0.484675320238872
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/23	268/9376	1.52109020116807	DUSP1	0.429183366110847