category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	6/20	298/9376	9.43892617449664	CSH1/LEP/EBI3/GDF15/CSH2/GH2	6.84472114963346
NA	NA	hsa04081	Hormone signaling	5/20	219/9376	10.703196347032	CSH1/CGA/LEP/CSH2/GH2	6.71762566365536
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	6/20	370/9376	7.60216216216216	CSH1/CGA/KISS1/LEP/CSH2/GH2	5.99068669891169
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	4/20	122/9376	15.3704918032787	CSH1/FOS/CSH2/GH2	7.38656167760116
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	3/20	52/9376	27.0461538461538	CGA/HSD3B1/CYP19A1	8.70762405260141
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	4/20	168/9376	11.1619047619048	CSH1/LEP/CSH2/GH2	6.14472760415601
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/20	362/9376	6.47513812154696	CSH1/FLT1/CSH2/NTRK2/GH2	4.91186155650001
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	4/20	300/9376	6.25066666666667	FLT1/GADD45G/FOS/NTRK2	4.27349658875383
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/20	65/9376	14.4246153846154	CGA/KISS1	5.02129684572103
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	2/20	66/9376	14.2060606060606	HSD3B1/CYP19A1	4.97766818415308
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/20	71/9376	13.2056338028169	CGA/FOS	4.77294962873239
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/20	75/9376	12.5013333333333	GADD45G/SERPINE1	4.62348581342724
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/20	87/9376	10.7770114942529	GADD45G/FOS	4.23581320670019
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/20	95/9376	9.86947368421053	FLT1/FOS	4.01714765724605
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/20	103/9376	9.10291262135922	SERPINE1/FOS	3.82300765469548
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/20	109/9376	8.60183486238532	EBI3/FOS	3.69077549079762
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/20	110/9376	8.52363636363636	FLT1/SERPINE1	3.66972500349473
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/20	137/9376	6.84379562043796	GADD45G/FOS	3.1856521194721
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/20	139/9376	6.7453237410072	FOS/KRT23	3.15509153456186
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/20	148/9376	6.33513513513514	GADD45G/FOS	3.02467013705322
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/20	157/9376	5.97197452229299	GADD45G/SERPINE1	2.90464019362681
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/20	157/9376	5.97197452229299	LEP/FOS	2.90464019362681
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/20	201/9376	4.66467661691542	FLT1/GADD45G	2.42820963933347
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/20	37/9376	12.6702702702703	GADD45G	3.28841876449314
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/20	226/9376	4.14867256637168	CGA/FOS	2.21527018416454
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/20	42/9376	11.1619047619048	SAT1	3.0515563689665
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/20	44/9376	10.6545454545455	MAN1C1	2.96774330711014
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/20	238/9376	3.93949579831933	FLT1/NTRK2	2.12369074732525
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/20	254/9376	3.69133858267717	FLT1/NTRK2	2.01046117779156
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/20	50/9376	9.376	SAT1	2.74555086965988
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/20	54/9376	8.68148148148148	CGA	2.61723577458828
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/20	56/9376	8.37142857142857	MAN1C1	2.55795705191804
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/20	59/9376	7.94576271186441	CGA	2.47436309727715
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/20	59/9376	7.94576271186441	GADD45G	2.47436309727715
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/20	63/9376	7.44126984126984	GADD45G	2.37166036611884
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/20	65/9376	7.21230769230769	HSD3B1	2.32363014703432
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/20	69/9376	6.79420289855072	FOS	2.23341236858006
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/20	70/9376	6.69714285714286	LEP	2.21197459653116
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/20	73/9376	6.42191780821918	GADD45G	2.15009861182797
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/20	73/9376	6.42191780821918	GADD45G	2.15009861182797
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/20	75/9376	6.25066666666667	CGA	2.11074508848556
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/20	76/9376	6.16842105263158	GADD45G	2.09160050570481
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/20	77/9376	6.08831168831169	GADD45G	2.07279558374471
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/20	77/9376	6.08831168831169	GADD45G	2.07279558374471
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/20	78/9376	6.01025641025641	FOS	2.05431961193387
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/20	78/9376	6.01025641025641	FOS	2.05431961193387
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/20	83/9376	5.64819277108434	AUTS2	1.9665307331922
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/20	88/9376	5.32727272727273	SERPINE1	1.88560199815955
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/20	90/9376	5.20888888888889	FOS	1.8549401663479
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/20	91/9376	5.15164835164835	FOS	1.83994920131691
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/20	93/9376	5.04086021505376	FOS	1.81061725869943
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/20	93/9376	5.04086021505376	CGA	1.81061725869943
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/20	93/9376	5.04086021505376	GADD45G	1.81061725869943
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/20	94/9376	4.98723404255319	FOS	1.7962649794616
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/20	97/9376	4.83298969072165	FOS	1.7543993606648
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/20	98/9376	4.78367346938775	HSD3B1	1.74082467142843
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/20	99/9376	4.73535353535354	FOS	1.72743239862243
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/20	99/9376	4.73535353535354	KRT23	1.72743239862243
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/20	99/9376	4.73535353535354	FOS	1.72743239862243
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/20	101/9376	4.64158415841584	SERPINE1	1.70117741494846
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/20	105/9376	4.46476190476191	GADD45G	1.65067009812867
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/20	109/9376	4.30091743119266	FOS	1.60263217667027
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/20	115/9376	4.07652173913043	FOS	1.53474241525005
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/20	115/9376	4.07652173913043	FOS	1.53474241525005
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/20	119/9376	3.93949579831933	FOS	1.49199278180774
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/20	120/9376	3.90666666666667	NTRK2	1.48159570283513
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/20	122/9376	3.84262295081967	LEP	1.46113369255766
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/20	122/9376	3.84262295081967	FOS	1.46113369255766
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/20	130/9376	3.60615384615385	FOS	1.38340808798312
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/20	133/9376	3.52481203007519	GADD45G	1.35582589498293
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/20	133/9376	3.52481203007519	FOS	1.35582589498293
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/20	136/9376	3.44705882352941	FOS	1.32902578600563
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/20	138/9376	3.39710144927536	FOS	1.31157312222264
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/20	140/9376	3.34857142857143	SERPINE1	1.29443831178112
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/20	142/9376	3.30140845070423	FOS	1.27761049307071
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/20	142/9376	3.30140845070423	FOS	1.27761049307071
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/20	150/9376	3.12533333333333	GADD45G	1.21316951184337
NA	NA	hsa04518	Integrin signaling	1/20	154/9376	3.04415584415584	FLT1	1.18254406776373
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/20	154/9376	3.04415584415584	FOS	1.18254406776373
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/20	155/9376	3.02451612903226	HSD3B1	1.17504259137042
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/20	157/9376	2.9859872611465	SERPINE1	1.16021882189705
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/20	158/9376	2.96708860759494	GADD45G	1.15289470408217
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/20	163/9376	2.8760736196319	FOS	1.11711703063961
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/20	170/9376	2.75764705882353	GADD45G	1.06924241130768
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/20	174/9376	2.69425287356322	MAN1C1	1.04295908148857
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/20	191/9376	2.4544502617801	NTRK2	0.93892630603139
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/20	196/9376	2.39183673469388	FOS	0.910438299969023
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/20	200/9376	2.344	FOS	0.888266111576046
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/20	203/9376	2.30935960591133	FLT1	0.871980534928235
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/20	205/9376	2.28682926829268	GADD45G	0.861281350443566
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/20	212/9376	2.21132075471698	FLT1	0.824783716395605
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/20	214/9376	2.19065420560748	FOS	0.814615975339017
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/20	216/9376	2.17037037037037	FOS	0.804559165500109
NA	NA	hsa04382	Cornified envelope formation	1/20	217/9376	2.16036866359447	KRT23	0.799571597783853
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/20	217/9376	2.16036866359447	FOS	0.799571597783853
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/20	224/9376	2.09285714285714	FOS	0.765393779034458
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/20	227/9376	2.06519823788546	FOS	0.751124769233806
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/20	238/9376	1.96974789915966	FOS	0.700611527276542
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/20	248/9376	1.89032258064516	FOS	0.656963047674288
NA	NA	hsa04517	IgSF CAM signaling	1/20	299/9376	1.56789297658863	GRIP1	0.461409416580453
NA	NA	hsa04519	Cadherin signaling	1/20	404/9376	1.16039603960396	KRT23	0.152368509890052