ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005179 hormone activity 6/36 132/18639 0.0454545454545455 23.5340909090909 1.84117535709687e-07 2.20941042851625e-05 GO:0051427 hormone receptor binding 4/36 34/18639 0.117647058823529 60.9117647058824 5.21433132249475e-07 3.12859879349685e-05 GO:0005131 growth hormone receptor binding 3/36 10/18639 0.3 155.325 7.86671163775093e-07 3.14668465510037e-05 GO:0008083 growth factor activity 4/36 162/18639 0.0246913580246914 12.7839506172839 0.000260755245164644 0.00782265735493933 GO:0004222 metalloendopeptidase activity 3/36 110/18639 0.0272727272727273 14.1204545454545 0.00123920124813136 0.0216834062988283 GO:0005126 cytokine receptor binding 4/36 275/18639 0.0145454545454545 7.53090909090909 0.00188343415210585 0.0216834062988283 GO:0005004 GPI-linked ephrin receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0005008 hepatocyte growth factor receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0005009 insulin receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0005011 macrophage colony-stimulating factor receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0005020 stem cell factor receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0008288 boss receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0036332 placental growth factor receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0038062 protein tyrosine kinase collagen receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0060175 brain-derived neurotrophic factor receptor activity 2/36 49/18639 0.0408163265306122 21.1326530612245 0.00402884115175095 0.0216834062988283 GO:0005006 epidermal growth factor receptor activity 2/36 50/18639 0.04 20.71 0.00419163263021726 0.0216834062988283 GO:0005007 fibroblast growth factor receptor activity 2/36 50/18639 0.04 20.71 0.00419163263021726 0.0216834062988283 GO:0005017 platelet-derived growth factor receptor activity 2/36 50/18639 0.04 20.71 0.00419163263021726 0.0216834062988283 GO:0005019 platelet-derived growth factor beta-receptor activity 2/36 50/18639 0.04 20.71 0.00419163263021726 0.0216834062988283 GO:0005010 insulin-like growth factor receptor activity 2/36 51/18639 0.0392156862745098 20.3039215686274 0.00435744255527401 0.0216834062988283 GO:0005021 vascular endothelial growth factor receptor activity 2/36 51/18639 0.0392156862745098 20.3039215686274 0.00435744255527401 0.0216834062988283 GO:0005030 neurotrophin receptor activity 2/36 51/18639 0.0392156862745098 20.3039215686274 0.00435744255527401 0.0216834062988283 GO:0005003 ephrin receptor activity 2/36 53/18639 0.0377358490566038 19.5377358490566 0.00469807136474612 0.0216834062988283 GO:0005005 transmembrane-ephrin receptor activity 2/36 53/18639 0.0377358490566038 19.5377358490566 0.00469807136474612 0.0216834062988283 GO:0038064 collagen receptor activity 2/36 53/18639 0.0377358490566038 19.5377358490566 0.00469807136474612 0.0216834062988283 GO:0008237 metallopeptidase activity 3/36 184/18639 0.016304347826087 8.44157608695652 0.00531898512763149 0.0236399339005844 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/36 60/18639 0.0333333333333333 17.2583333333333 0.0059836578180425 0.0256442477916107 GO:0016500 protein-hormone receptor activity 2/36 67/18639 0.0298507462686567 15.455223880597 0.00741153754166567 0.0298812746522502 GO:0004175 endopeptidase activity 4/36 405/18639 0.00987654320987654 5.11358024691358 0.00747031866306256 0.0298812746522502 GO:0019199 transmembrane receptor protein kinase activity 2/36 78/18639 0.0256410256410256 13.275641025641 0.00993362333481205 0.038452735489595 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/36 10/18639 0.1 51.775 0.0191519170615361 0.0696433347692221 GO:0043121 neurotrophin binding 1/36 10/18639 0.1 51.775 0.0191519170615361 0.0696433347692221 GO:0035401 histone H3Y41 kinase activity 2/36 115/18639 0.0173913043478261 9.00434782608696 0.0207386891373462 0.07110407704233 GO:0140801 histone H2AXY142 kinase activity 2/36 115/18639 0.0173913043478261 9.00434782608696 0.0207386891373462 0.07110407704233 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/36 13/18639 0.0769230769230769 39.8269230769231 0.0248276205365063 0.0827587351216878 GO:0043176 amine binding 1/36 14/18639 0.0714285714285714 36.9821428571429 0.0267124162876439 0.0836887906557815 GO:0002020 protease binding 2/36 136/18639 0.0147058823529412 7.61397058823529 0.0283211331710772 0.0836887906557815 GO:0019838 growth factor binding 2/36 136/18639 0.0147058823529412 7.61397058823529 0.0283211331710772 0.0836887906557815 GO:0004559 alpha-mannosidase activity 1/36 15/18639 0.0666666666666667 34.5166666666667 0.0285936701407253 0.0836887906557815 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/36 15/18639 0.0666666666666667 34.5166666666667 0.0285936701407253 0.0836887906557815 GO:0004713 protein tyrosine kinase activity 2/36 140/18639 0.0142857142857143 7.39642857142857 0.0298744571344561 0.0850364331958464 GO:0015923 mannosidase activity 1/36 16/18639 0.0625 32.359375 0.0304713885618449 0.0850364331958464 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/36 21/18639 0.0476190476190476 24.6547619047619 0.0398071747003502 0.106152465867601 GO:0051428 peptide hormone receptor binding 1/36 21/18639 0.0476190476190476 24.6547619047619 0.0398071747003502 0.106152465867601 GO:0070412 R-SMAD binding 1/36 26/18639 0.0384615384615385 19.9134615384615 0.049055538388672 0.127970969709579 GO:0008395 steroid hydroxylase activity 1/36 27/18639 0.037037037037037 19.1759259259259 0.0508947905574793 0.129944146104202 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/36 32/18639 0.03125 16.1796875 0.0600392967027265 0.150098241756816 GO:0140416 transcription regulator inhibitor activity 1/36 33/18639 0.0303030303030303 15.6893939393939 0.061857891066068 0.15148871281486 GO:0019825 oxygen binding 1/36 34/18639 0.0294117647058824 15.2279411764706 0.0636730644467852 0.152815354672285 GO:0016229 steroid dehydrogenase activity 1/36 35/18639 0.0285714285714286 14.7928571428571 0.0654848230966063 0.154081936697897 GO:0071855 neuropeptide receptor binding 1/36 40/18639 0.025 12.94375 0.0744926134175744 0.169447299516991 GO:0005125 cytokine activity 2/36 234/18639 0.00854700854700855 4.42521367521368 0.0748392239533378 0.169447299516991 GO:0035198 miRNA binding 1/36 42/18639 0.0238095238095238 12.327380952381 0.0780720440014808 0.173493431114402 GO:0001046 core promoter sequence-specific DNA binding 1/36 44/18639 0.0227272727272727 11.7670454545455 0.0816380141156977 0.178119303525159 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/36 46/18639 0.0217391304347826 11.2554347826087 0.0851905729374525 0.179348574605163 GO:0030291 protein serine/threonine kinase inhibitor activity 1/36 46/18639 0.0217391304347826 11.2554347826087 0.0851905729374525 0.179348574605163 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/36 48/18639 0.0208333333333333 10.7864583333333 0.0887297694695702 0.180467327734719 GO:0140693 molecular condensate scaffold activity 1/36 48/18639 0.0208333333333333 10.7864583333333 0.0887297694695702 0.180467327734719 GO:0030159 signaling receptor complex adaptor activity 1/36 52/18639 0.0192307692307692 9.95673076923077 0.0957682708077878 0.189081281434135 GO:0016860 intramolecular oxidoreductase activity 1/36 53/18639 0.0188679245283019 9.7688679245283 0.0975196207970774 0.189081281434135 GO:0017069 snRNA binding 1/36 54/18639 0.0185185185185185 9.58796296296296 0.0992676727529208 0.189081281434135 GO:0140463 chromatin-protein adaptor activity 1/36 54/18639 0.0185185185185185 9.58796296296296 0.0992676727529208 0.189081281434135 GO:0061980 regulatory RNA binding 1/36 58/18639 0.0172413793103448 8.92672413793103 0.106227020751819 0.19917566390966 GO:1990841 promoter-specific chromatin binding 1/36 68/18639 0.0147058823529412 7.61397058823529 0.123397465980279 0.227448664530179 GO:0008080 N-acetyltransferase activity 1/36 69/18639 0.0144927536231884 7.5036231884058 0.125096765491598 0.227448664530179 GO:0046332 SMAD binding 1/36 79/18639 0.0126582278481013 6.55379746835443 0.141914572303553 0.253374639073689 GO:0048306 calcium-dependent protein binding 1/36 80/18639 0.0125 6.471875 0.143578962141757 0.253374639073689 GO:0141003 histone H2AX kinase activity 2/36 354/18639 0.00564971751412429 2.92514124293785 0.148989277366085 0.25502924205269 GO:0004860 protein kinase inhibitor activity 1/36 84/18639 0.0119047619047619 6.16369047619048 0.15020519059687 0.25502924205269 GO:0140996 histone H3 kinase activity 2/36 357/18639 0.00560224089635854 2.90056022408964 0.151000560522518 0.25502924205269 GO:0035173 histone kinase activity 2/36 360/18639 0.00555555555555556 2.87638888888889 0.153017545231614 0.25502924205269 GO:0019210 kinase inhibitor activity 1/36 90/18639 0.0111111111111111 5.75277777777778 0.160051170071517 0.261209544858755 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/36 91/18639 0.010989010989011 5.68956043956044 0.161681347325139 0.261209544858755 GO:0016410 N-acyltransferase activity 1/36 94/18639 0.0106382978723404 5.50797872340426 0.166553444805646 0.261209544858755 GO:0004867 serine-type endopeptidase inhibitor activity 1/36 95/18639 0.0105263157894737 5.45 0.168171351302653 0.261209544858755 GO:0004896 cytokine receptor activity 1/36 96/18639 0.0104166666666667 5.39322916666667 0.169786204158191 0.261209544858755 GO:0016407 acetyltransferase activity 1/36 96/18639 0.0104166666666667 5.39322916666667 0.169786204158191 0.261209544858755 GO:0004497 monooxygenase activity 1/36 106/18639 0.00943396226415094 4.88443396226415 0.185768009312176 0.278652013968264 GO:0008013 beta-catenin binding 1/36 106/18639 0.00943396226415094 4.88443396226415 0.185768009312176 0.278652013968264 GO:0004857 enzyme inhibitor activity 2/36 416/18639 0.00480769230769231 2.48918269230769 0.191559549875227 0.283791925741076 GO:0001221 transcription coregulator binding 1/36 115/18639 0.00869565217391304 4.50217391304348 0.199895604024058 0.287786495295429 GO:0017124 SH3 domain binding 1/36 115/18639 0.00869565217391304 4.50217391304348 0.199895604024058 0.287786495295429 GO:0009055 electron transfer activity 1/36 116/18639 0.00862068965517241 4.46336206896552 0.201450546706801 0.287786495295429 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/36 122/18639 0.00819672131147541 4.24385245901639 0.210718690492555 0.297485210107137 GO:0035591 signaling adaptor activity 1/36 129/18639 0.00775193798449612 4.01356589147287 0.221399385303158 0.307467146861196 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/36 130/18639 0.00769230769230769 3.98269230769231 0.222913681474367 0.307467146861196 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/36 132/18639 0.00757575757575758 3.92234848484849 0.22593368860235 0.308091393548659 GO:0020037 heme binding 1/36 142/18639 0.00704225352112676 3.64612676056338 0.240863380961011 0.324759614778891 GO:0046906 tetrapyrrole binding 1/36 152/18639 0.00657894736842105 3.40625 0.255512967446405 0.340683956595206 GO:0005506 iron ion binding 1/36 154/18639 0.00649350649350649 3.36201298701299 0.258409723130923 0.34076007445836 GO:0140375 immune receptor activity 1/36 156/18639 0.00641025641025641 3.31891025641026 0.261295519609319 0.340820242968677 GO:0004866 endopeptidase inhibitor activity 1/36 161/18639 0.0062111801242236 3.21583850931677 0.268462328271407 0.34640300422117 GO:0030414 peptidase inhibitor activity 1/36 169/18639 0.00591715976331361 3.06360946745562 0.279788834396087 0.35717723539926 GO:0004252 serine-type endopeptidase activity 1/36 176/18639 0.00568181818181818 2.94176136363636 0.289559519208226 0.363011696975588 GO:0043021 ribonucleoprotein complex binding 1/36 177/18639 0.00564971751412429 2.92514124293785 0.290944768480203 0.363011696975588 GO:0016853 isomerase activity 1/36 180/18639 0.00555555555555556 2.87638888888889 0.295084778817372 0.363011696975588 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/36 181/18639 0.00552486187845304 2.86049723756906 0.296459552530063 0.363011696975588 GO:0061135 endopeptidase regulator activity 1/36 184/18639 0.00543478260869565 2.81385869565217 0.300568251819157 0.36432515372019 GO:0008236 serine-type peptidase activity 1/36 194/18639 0.00515463917525773 2.66881443298969 0.314096127624966 0.376915353149959 GO:0017171 serine hydrolase activity 1/36 198/18639 0.00505050505050505 2.61489898989899 0.319435751277686 0.379527625280419 GO:0061134 peptidase regulator activity 1/36 226/18639 0.00442477876106195 2.29092920353982 0.355697803770527 0.418468004435914 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/36 229/18639 0.00436681222707424 2.26091703056769 0.359469728106787 0.418799683231209 GO:0019887 protein kinase regulator activity 1/36 255/18639 0.00392156862745098 2.03039215686274 0.391272900617573 0.451468731481815 GO:0005096 GTPase activator activity 1/36 271/18639 0.003690036900369 1.91051660516605 0.410075283133523 0.468657466438312 GO:0030246 carbohydrate binding 1/36 280/18639 0.00357142857142857 1.84910714285714 0.420402209252114 0.475295660502132 GO:0031267 small GTPase binding 1/36 283/18639 0.00353356890459364 1.82950530035336 0.423805297281068 0.475295660502132 GO:0019207 kinase regulator activity 1/36 287/18639 0.00348432055749129 1.80400696864112 0.428312543351699 0.475902825946332 GO:0001664 G protein-coupled receptor binding 1/36 297/18639 0.00336700336700337 1.74326599326599 0.439431212341885 0.483777481477304 GO:0031625 ubiquitin protein ligase binding 1/36 302/18639 0.0033112582781457 1.71440397350993 0.44491142128695 0.485357914131218 GO:0051020 GTPase binding 1/36 315/18639 0.00317460317460317 1.64365079365079 0.458917330007258 0.49612684325109 GO:0044389 ubiquitin-like protein ligase binding 1/36 322/18639 0.0031055900621118 1.60791925465838 0.466316035249495 0.499624323481601 GO:0003924 GTPase activity 1/36 331/18639 0.00302114803625378 1.56419939577039 0.4756842523909 0.505151418468212 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 1/36 349/18639 0.00286532951289398 1.48352435530086 0.493943465557927 0.519940490060976 GO:0016887 ATP hydrolysis activity 1/36 417/18639 0.00239808153477218 1.2416067146283 0.557506122633627 0.581745519269872 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 1/36 484/18639 0.00206611570247934 1.06973140495868 0.612511002660404 0.617858521817495 GO:0140297 DNA-binding transcription factor binding 1/36 488/18639 0.00204918032786885 1.0609631147541 0.615575571770817 0.617858521817495 GO:0030695 GTPase regulator activity 1/36 489/18639 0.00204498977505112 1.05879345603272 0.61633802449608 0.617858521817495 GO:0060589 nucleoside-triphosphatase regulator activity 1/36 490/18639 0.00204081632653061 1.05663265306122 0.617099006926832 0.617858521817495 GO:0001216 DNA-binding transcription activator activity 1/36 491/18639 0.00203665987780041 1.05448065173116 0.617858521817495 0.617858521817495