ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 18/85 175/18639 0.102857142857143 22.554756302521 9.23756919140613e-20 2.67889506550778e-17 GO:0005179 hormone activity 9/85 132/18639 0.0681818181818182 14.9510695187166 8.89472247737094e-09 1.28973475921879e-06 GO:0005131 growth hormone receptor binding 3/85 10/18639 0.3 65.7847058823529 1.07328737680083e-05 0.00103751113090747 GO:0051427 hormone receptor binding 4/85 34/18639 0.117647058823529 25.7979238754325 1.68273444897476e-05 0.0012199824755067 GO:0031386 protein tag activity 3/85 15/18639 0.2 43.8564705882353 4.00294742565402e-05 0.00193475792239945 GO:0141047 molecular tag activity 3/85 15/18639 0.2 43.8564705882353 4.00294742565402e-05 0.00193475792239945 GO:0008083 growth factor activity 6/85 162/18639 0.037037037037037 8.12156862745098 9.75047765902456e-05 0.00403948360159589 GO:0045296 cadherin binding 8/85 334/18639 0.0239520958083832 5.25227192673477 0.000141906918052256 0.00514412577939427 GO:0048027 mRNA 5'-UTR binding 3/85 24/18639 0.125 27.4102941176471 0.000172860603399606 0.00556995277620954 GO:0019843 rRNA binding 4/85 65/18639 0.0615384615384615 13.4942986425339 0.00022062716773635 0.00639818786435414 GO:0004857 enzyme inhibitor activity 8/85 416/18639 0.0192307692307692 4.21696832579186 0.00061833286301329 0.0163015027521685 GO:0048185 activin binding 2/85 11/18639 0.181818181818182 39.8695187165775 0.00110060736552412 0.0245520104616919 GO:1990948 ubiquitin ligase inhibitor activity 2/85 11/18639 0.181818181818182 39.8695187165775 0.00110060736552412 0.0245520104616919 GO:0044548 S100 protein binding 2/85 14/18639 0.142857142857143 31.3260504201681 0.00180488705756606 0.0373869461924398 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/85 15/18639 0.133333333333333 29.2376470588235 0.00207640360884444 0.0401438031043259 GO:0004601 peroxidase activity 3/85 57/18639 0.0526315789473684 11.5411764705882 0.00224235962510749 0.0406427682050733 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/85 59/18639 0.0508474576271186 11.1499501495513 0.00247509662078085 0.042222236472144 GO:0070064 proline-rich region binding 2/85 18/18639 0.111111111111111 24.3647058823529 0.00299887265579531 0.0457722668516127 GO:0098641 cadherin binding involved in cell-cell adhesion 2/85 18/18639 0.111111111111111 24.3647058823529 0.00299887265579531 0.0457722668516127 GO:0019838 growth factor binding 4/85 136/18639 0.0294117647058824 6.44948096885813 0.00347828683057825 0.0504351590433846 GO:0098631 cell adhesion mediator activity 3/85 76/18639 0.0394736842105263 8.65588235294118 0.00506323047380273 0.0699208017810853 GO:0048306 calcium-dependent protein binding 3/85 80/18639 0.0375 8.22308823529412 0.00584076857382043 0.0769919493821784 GO:0016209 antioxidant activity 3/85 86/18639 0.0348837209302326 7.64938440492476 0.0071345918996739 0.0899578978654535 GO:0005126 cytokine receptor binding 5/85 275/18639 0.0181818181818182 3.98695187165775 0.00847690728057657 0.102429296306967 GO:0019207 kinase regulator activity 5/85 287/18639 0.0174216027874564 3.82025005124001 0.0100771091934095 0.11689446664355 GO:0055106 ubiquitin-protein transferase regulator activity 2/85 36/18639 0.0555555555555556 12.1823529411765 0.0117099330579286 0.130610791799973 GO:0031625 ubiquitin protein ligase binding 5/85 302/18639 0.0165562913907285 3.63050253213868 0.012355324498458 0.13270533720566 GO:0008307 structural constituent of muscle 2/85 42/18639 0.0476190476190476 10.4420168067227 0.0157240516680017 0.159059764527056 GO:0044389 ubiquitin-like protein ligase binding 5/85 322/18639 0.015527950310559 3.40500548045305 0.0159059764527056 0.159059764527056 GO:0001046 core promoter sequence-specific DNA binding 2/85 44/18639 0.0454545454545455 9.96737967914438 0.0171753320911839 0.166028210214778 GO:0051082 unfolded protein binding 3/85 121/18639 0.0247933884297521 5.43675255226057 0.0179220843289296 0.167658208238373 GO:0005125 cytokine activity 4/85 234/18639 0.0170940170940171 3.74841628959276 0.0222334368142891 0.201490521129495 GO:0005246 calcium channel regulator activity 2/85 53/18639 0.0377358490566038 8.27480577136515 0.0243681411848036 0.207845910105678 GO:0016860 intramolecular oxidoreductase activity 2/85 53/18639 0.0377358490566038 8.27480577136515 0.0243681411848036 0.207845910105678 GO:0051287 NAD binding 2/85 54/18639 0.037037037037037 8.12156862745098 0.0252315453305297 0.209061375595817 GO:0098632 cell-cell adhesion mediator activity 2/85 55/18639 0.0363636363636364 7.97390374331551 0.0261073114324561 0.210308897650341 GO:0019887 protein kinase regulator activity 4/85 255/18639 0.0156862745098039 3.439723183391 0.0292659575829339 0.229381829704076 GO:0019209 kinase activator activity 3/85 148/18639 0.0202702702702703 4.44491255961844 0.0302009191124293 0.230480698489592 GO:0004866 endopeptidase inhibitor activity 3/85 161/18639 0.0186335403726708 4.08600657654366 0.0373521036488272 0.27774641174769 GO:0030414 peptidase inhibitor activity 3/85 169/18639 0.0177514792899408 3.89258614688479 0.0421465034060805 0.28447949306024 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/85 10/18639 0.1 21.9282352941176 0.0446893174501952 0.28447949306024 GO:0019531 oxalate transmembrane transporter activity 1/85 10/18639 0.1 21.9282352941176 0.0446893174501952 0.28447949306024 GO:0030957 Tat protein binding 1/85 10/18639 0.1 21.9282352941176 0.0446893174501952 0.28447949306024 GO:0043021 ribonucleoprotein complex binding 3/85 177/18639 0.0169491525423729 3.71665004985045 0.0472356225958872 0.28447949306024 GO:0005114 type II transforming growth factor beta receptor binding 1/85 11/18639 0.0909090909090909 19.9347593582888 0.0490481884586621 0.28447949306024 GO:0008199 ferric iron binding 1/85 11/18639 0.0909090909090909 19.9347593582888 0.0490481884586621 0.28447949306024 GO:0008271 secondary active sulfate transmembrane transporter activity 1/85 11/18639 0.0909090909090909 19.9347593582888 0.0490481884586621 0.28447949306024 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/85 11/18639 0.0909090909090909 19.9347593582888 0.0490481884586621 0.28447949306024 GO:0034713 type I transforming growth factor beta receptor binding 1/85 11/18639 0.0909090909090909 19.9347593582888 0.0490481884586621 0.28447949306024 GO:0070697 activin receptor binding 1/85 11/18639 0.0909090909090909 19.9347593582888 0.0490481884586621 0.28447949306024 GO:0061135 endopeptidase regulator activity 3/85 184/18639 0.016304347826087 3.5752557544757 0.051926210171662 0.286710131692237 GO:0097371 MDM2/MDM4 family protein binding 1/85 12/18639 0.0833333333333333 18.2735294117647 0.0533874038323475 0.286710131692237 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/85 12/18639 0.0833333333333333 18.2735294117647 0.0533874038323475 0.286710131692237 GO:0140900 chloride:bicarbonate antiporter activity 1/85 12/18639 0.0833333333333333 18.2735294117647 0.0533874038323475 0.286710131692237 GO:0004860 protein kinase inhibitor activity 2/85 84/18639 0.0238095238095238 5.22100840336134 0.0563342539590543 0.29703515723865 GO:0005542 folic acid binding 1/85 13/18639 0.0769230769230769 16.8678733031674 0.0577070511547426 0.29884008633706 GO:0043176 amine binding 1/85 14/18639 0.0714285714285714 15.663025210084 0.0620072176237565 0.305135192309269 GO:0019210 kinase inhibitor activity 2/85 90/18639 0.0222222222222222 4.87294117647059 0.0636099596428827 0.305135192309269 GO:0000774 adenyl-nucleotide exchange factor activity 1/85 15/18639 0.0666666666666667 14.6188235294118 0.066287990053393 0.305135192309269 GO:0005523 tropomyosin binding 1/85 15/18639 0.0666666666666667 14.6188235294118 0.066287990053393 0.305135192309269 GO:0015116 sulfate transmembrane transporter activity 1/85 15/18639 0.0666666666666667 14.6188235294118 0.066287990053393 0.305135192309269 GO:0016846 carbon-sulfur lyase activity 1/85 15/18639 0.0666666666666667 14.6188235294118 0.066287990053393 0.305135192309269 GO:0017081 chloride channel regulator activity 1/85 15/18639 0.0666666666666667 14.6188235294118 0.066287990053393 0.305135192309269 GO:0004867 serine-type endopeptidase inhibitor activity 2/85 95/18639 0.0210526315789474 4.61647058823529 0.0699017309104689 0.305363312147347 GO:0005159 insulin-like growth factor receptor binding 1/85 16/18639 0.0625 13.7051470588235 0.0705494548754215 0.305363312147347 GO:0016722 oxidoreductase activity, acting on metal ions 1/85 16/18639 0.0625 13.7051470588235 0.0705494548754215 0.305363312147347 GO:0043023 ribosomal large subunit binding 1/85 16/18639 0.0625 13.7051470588235 0.0705494548754215 0.305363312147347 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/85 17/18639 0.0588235294117647 12.8989619377163 0.0747916981410387 0.318964595013253 GO:0003746 translation elongation factor activity 1/85 18/18639 0.0555555555555556 12.1823529411765 0.0790148055225238 0.332091211616404 GO:0003756 protein disulfide isomerase activity 1/85 19/18639 0.0526315789473684 11.5411764705882 0.0832188623148862 0.339908029173479 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/85 19/18639 0.0526315789473684 11.5411764705882 0.0832188623148862 0.339908029173479 GO:0061134 peptidase regulator activity 3/85 226/18639 0.0132743362831858 2.91082769390942 0.084471878810794 0.340233956321253 GO:0043024 ribosomal small subunit binding 1/85 20/18639 0.05 10.9641176470588 0.0874039534375093 0.344585327970416 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/85 21/18639 0.0476190476190476 10.4420168067227 0.0915701634357805 0.344585327970416 GO:0036122 BMP binding 1/85 21/18639 0.0476190476190476 10.4420168067227 0.0915701634357805 0.344585327970416 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/85 21/18639 0.0476190476190476 10.4420168067227 0.0915701634357805 0.344585327970416 GO:0051428 peptide hormone receptor binding 1/85 21/18639 0.0476190476190476 10.4420168067227 0.0915701634357805 0.344585327970416 GO:0043022 ribosome binding 2/85 112/18639 0.0178571428571429 3.91575630252101 0.0926815709713533 0.344585327970416 GO:0004602 glutathione peroxidase activity 1/85 23/18639 0.0434782608695652 9.53401534526854 0.0998462763806088 0.361942751879707 GO:0017134 fibroblast growth factor binding 1/85 23/18639 0.0434782608695652 9.53401534526854 0.0998462763806088 0.361942751879707 GO:0050431 transforming growth factor beta binding 1/85 24/18639 0.0416666666666667 9.13676470588235 0.103956346562584 0.367650493940846 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/85 24/18639 0.0416666666666667 9.13676470588235 0.103956346562584 0.367650493940846 GO:0003713 transcription coactivator activity 3/85 256/18639 0.01171875 2.56971507352941 0.111891378858908 0.373736432251097 GO:0005160 transforming growth factor beta receptor binding 1/85 26/18639 0.0384615384615385 8.43393665158371 0.112120929675329 0.373736432251097 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/85 26/18639 0.0384615384615385 8.43393665158371 0.112120929675329 0.373736432251097 GO:0008198 ferrous iron binding 1/85 26/18639 0.0384615384615385 8.43393665158371 0.112120929675329 0.373736432251097 GO:0070412 R-SMAD binding 1/85 26/18639 0.0384615384615385 8.43393665158371 0.112120929675329 0.373736432251097 GO:0004364 glutathione transferase activity 1/85 27/18639 0.037037037037037 8.12156862745098 0.116175607641138 0.382851434271933 GO:0051019 mitogen-activated protein kinase binding 1/85 28/18639 0.0357142857142857 7.83151260504202 0.12021198596429 0.383368548793164 GO:0097718 disordered domain specific binding 1/85 28/18639 0.0357142857142857 7.83151260504202 0.12021198596429 0.383368548793164 GO:0003785 actin monomer binding 1/85 29/18639 0.0344827586206897 7.56146044624746 0.124230146256216 0.383368548793164 GO:0043236 laminin binding 1/85 29/18639 0.0344827586206897 7.56146044624746 0.124230146256216 0.383368548793164 GO:0002020 protease binding 2/85 136/18639 0.0147058823529412 3.22474048442907 0.127834761147927 0.383368548793164 GO:0044325 transmembrane transporter binding 2/85 136/18639 0.0147058823529412 3.22474048442907 0.127834761147927 0.383368548793164 GO:0001968 fibronectin binding 1/85 30/18639 0.0333333333333333 7.30941176470588 0.128230169768748 0.383368548793164 GO:0016769 transferase activity, transferring nitrogenous groups 1/85 30/18639 0.0333333333333333 7.30941176470588 0.128230169768748 0.383368548793164 GO:0033612 receptor serine/threonine kinase binding 1/85 30/18639 0.0333333333333333 7.30941176470588 0.128230169768748 0.383368548793164 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/85 31/18639 0.032258064516129 7.07362428842505 0.132212137395684 0.384041238241045 GO:0005452 solute:inorganic anion antiporter activity 1/85 31/18639 0.032258064516129 7.07362428842505 0.132212137395684 0.384041238241045 GO:0030295 protein kinase activator activity 2/85 139/18639 0.0143884892086331 3.15514176893779 0.132428013186567 0.384041238241045 GO:0015106 bicarbonate transmembrane transporter activity 1/85 32/18639 0.03125 6.85257352941176 0.136176129674348 0.387167427505498 GO:0051059 NF-kappaB binding 1/85 32/18639 0.03125 6.85257352941176 0.136176129674348 0.387167427505498 GO:0030296 protein tyrosine kinase activator activity 1/85 33/18639 0.0303030303030303 6.64491978609626 0.140122226787137 0.394518890954076 GO:0015035 protein-disulfide reductase activity 1/85 34/18639 0.0294117647058824 6.44948096885813 0.144050508563075 0.401679302723959 GO:0005154 epidermal growth factor receptor binding 1/85 35/18639 0.0285714285714286 6.26521008403361 0.147961054479341 0.408654340942943 GO:0045505 dynein intermediate chain binding 1/85 36/18639 0.0277777777777778 6.09117647058823 0.15185394366281 0.415449468511462 GO:0000146 microfilament motor activity 1/85 38/18639 0.0263157894736842 5.77058823529412 0.159587066596455 0.422080474620051 GO:0099106 ion channel regulator activity 2/85 160/18639 0.0125 2.74102941176471 0.165535713426571 0.422080474620051 GO:0015036 disulfide oxidoreductase activity 1/85 40/18639 0.025 5.48205882352941 0.167250503430633 0.422080474620051 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/85 40/18639 0.025 5.48205882352941 0.167250503430633 0.422080474620051 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/85 40/18639 0.025 5.48205882352941 0.167250503430633 0.422080474620051 GO:0071855 neuropeptide receptor binding 1/85 40/18639 0.025 5.48205882352941 0.167250503430633 0.422080474620051 GO:0071949 FAD binding 1/85 40/18639 0.025 5.48205882352941 0.167250503430633 0.422080474620051 GO:0017080 sodium channel regulator activity 1/85 41/18639 0.024390243902439 5.34835007173601 0.171056283698841 0.422080474620051 GO:0016247 channel regulator activity 2/85 168/18639 0.0119047619047619 2.61050420168067 0.178509585439263 0.422080474620051 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/85 43/18639 0.0232558139534884 5.09958960328317 0.178616353223121 0.422080474620051 GO:0141108 transporter regulator activity 2/85 170/18639 0.0117647058823529 2.57979238754325 0.181778105399979 0.422080474620051 GO:0140297 DNA-binding transcription factor binding 4/85 488/18639 0.00819672131147541 1.79739633558341 0.183241547434897 0.422080474620051 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/85 46/18639 0.0217391304347826 4.76700767263427 0.189828875669628 0.422080474620051 GO:0030291 protein serine/threonine kinase inhibitor activity 1/85 46/18639 0.0217391304347826 4.76700767263427 0.189828875669628 0.422080474620051 GO:0004252 serine-type endopeptidase activity 2/85 176/18639 0.0113636363636364 2.4918449197861 0.191636770077598 0.422080474620051 GO:0001784 phosphotyrosine residue binding 1/85 47/18639 0.0212765957446809 4.66558197747184 0.193532664491663 0.422080474620051 GO:0016853 isomerase activity 2/85 180/18639 0.0111111111111111 2.43647058823529 0.198249253442526 0.422080474620051 GO:0005004 GPI-linked ephrin receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0005008 hepatocyte growth factor receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0005009 insulin receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0005011 macrophage colony-stimulating factor receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0005020 stem cell factor receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0008288 boss receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0036332 placental growth factor receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0038062 protein tyrosine kinase collagen receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0060175 brain-derived neurotrophic factor receptor activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0060590 ATPase regulator activity 1/85 49/18639 0.0204081632653061 4.47515006002401 0.200890114888117 0.422080474620051 GO:0005006 epidermal growth factor receptor activity 1/85 50/18639 0.02 4.38564705882353 0.20454392555162 0.422080474620051 GO:0005007 fibroblast growth factor receptor activity 1/85 50/18639 0.02 4.38564705882353 0.20454392555162 0.422080474620051 GO:0005017 platelet-derived growth factor receptor activity 1/85 50/18639 0.02 4.38564705882353 0.20454392555162 0.422080474620051 GO:0005019 platelet-derived growth factor beta-receptor activity 1/85 50/18639 0.02 4.38564705882353 0.20454392555162 0.422080474620051 GO:1901981 phosphatidylinositol phosphate binding 2/85 185/18639 0.0108108108108108 2.3706200317965 0.206554178433329 0.422080474620051 GO:0005010 insulin-like growth factor receptor activity 1/85 51/18639 0.0196078431372549 4.29965397923875 0.208181225370228 0.422080474620051 GO:0005021 vascular endothelial growth factor receptor activity 1/85 51/18639 0.0196078431372549 4.29965397923875 0.208181225370228 0.422080474620051 GO:0005030 neurotrophin receptor activity 1/85 51/18639 0.0196078431372549 4.29965397923875 0.208181225370228 0.422080474620051 GO:0005080 protein kinase C binding 1/85 52/18639 0.0192307692307692 4.21696832579186 0.211802088068933 0.422080474620051 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/85 349/18639 0.00859598853868195 1.88494859261756 0.21319769232014 0.422080474620051 GO:0005003 ephrin receptor activity 1/85 53/18639 0.0188679245283019 4.13740288568258 0.215406587047474 0.422080474620051 GO:0005005 transmembrane-ephrin receptor activity 1/85 53/18639 0.0188679245283019 4.13740288568258 0.215406587047474 0.422080474620051 GO:0017046 peptide hormone binding 1/85 53/18639 0.0188679245283019 4.13740288568258 0.215406587047474 0.422080474620051 GO:0038064 collagen receptor activity 1/85 53/18639 0.0188679245283019 4.13740288568258 0.215406587047474 0.422080474620051 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/85 54/18639 0.0185185185185185 4.06078431372549 0.218994795381756 0.423389937738062 GO:0050661 NADP binding 1/85 54/18639 0.0185185185185185 4.06078431372549 0.218994795381756 0.423389937738062 GO:0008236 serine-type peptidase activity 2/85 194/18639 0.0103092783505155 2.26064281382656 0.221594830062667 0.424633999271881 GO:0140313 molecular sequestering activity 1/85 55/18639 0.0181818181818182 3.98695187165775 0.222566785825262 0.424633999271881 GO:0017171 serine hydrolase activity 2/85 198/18639 0.0101010101010101 2.21497326203209 0.228310223923393 0.432744868874406 GO:0016829 lyase activity 2/85 200/18639 0.01 2.19282352941176 0.231673664730771 0.436268589428074 GO:0015459 potassium channel regulator activity 1/85 59/18639 0.0169491525423729 3.71665004985045 0.236694012554908 0.440008100262329 GO:0045309 protein phosphorylated amino acid binding 1/85 59/18639 0.0169491525423729 3.71665004985045 0.236694012554908 0.440008100262329 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/85 60/18639 0.0166666666666667 3.65470588235294 0.240185993660012 0.443655657079003 GO:0015026 coreceptor activity 1/85 61/18639 0.0163934426229508 3.59479267116683 0.243662186702635 0.444415309080278 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/85 61/18639 0.0163934426229508 3.59479267116683 0.243662186702635 0.444415309080278 GO:1901682 sulfur compound transmembrane transporter activity 1/85 63/18639 0.0158730158730159 3.48067226890756 0.250567490431235 0.454153576406613 GO:0038024 cargo receptor activity 1/85 65/18639 0.0153846153846154 3.37357466063348 0.257410484296958 0.46365863631129 GO:0016500 protein-hormone receptor activity 1/85 67/18639 0.0149253731343284 3.27287093942054 0.264191723917786 0.470034355436552 GO:0050840 extracellular matrix binding 1/85 67/18639 0.0149253731343284 3.27287093942054 0.264191723917786 0.470034355436552 GO:1990841 promoter-specific chromatin binding 1/85 68/18639 0.0147058823529412 3.22474048442907 0.267559358177262 0.473123255313451 GO:0008080 N-acetyltransferase activity 1/85 69/18639 0.0144927536231884 3.17800511508951 0.270911760016417 0.476147941847035 GO:0097110 scaffold protein binding 1/85 70/18639 0.0142857142857143 3.13260504201681 0.274248997517687 0.479109694458611 GO:0004175 endopeptidase activity 3/85 405/18639 0.00740740740740741 1.6243137254902 0.28140138978042 0.487528899262967 GO:0048029 monosaccharide binding 1/85 74/18639 0.0135135135135135 2.96327503974563 0.287447655297487 0.487528899262967 GO:0044183 protein folding chaperone 1/85 75/18639 0.0133333333333333 2.92376470588235 0.290710081868977 0.487528899262967 GO:0019199 transmembrane receptor protein kinase activity 1/85 78/18639 0.0128205128205128 2.81131221719457 0.300409052645712 0.487528899262967 GO:0016835 carbon-oxygen lyase activity 1/85 79/18639 0.0126582278481013 2.77572598659717 0.303612825638822 0.487528899262967 GO:0046332 SMAD binding 1/85 79/18639 0.0126582278481013 2.77572598659717 0.303612825638822 0.487528899262967 GO:0000049 tRNA binding 1/85 80/18639 0.0125 2.74102941176471 0.306802098797265 0.487528899262967 GO:0001618 virus receptor activity 1/85 81/18639 0.0123456790123457 2.70718954248366 0.309976936967545 0.487528899262967 GO:0033192 calmodulin-dependent protein phosphatase activity 1/85 81/18639 0.0123456790123457 2.70718954248366 0.309976936967545 0.487528899262967 GO:0140791 histone H2AXS140 phosphatase activity 1/85 81/18639 0.0123456790123457 2.70718954248366 0.309976936967545 0.487528899262967 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/85 81/18639 0.0123456790123457 2.70718954248366 0.309976936967545 0.487528899262967 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/85 81/18639 0.0123456790123457 2.70718954248366 0.309976936967545 0.487528899262967 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/85 81/18639 0.0123456790123457 2.70718954248366 0.309976936967545 0.487528899262967 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/85 81/18639 0.0123456790123457 2.70718954248366 0.309976936967545 0.487528899262967 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/85 81/18639 0.0123456790123457 2.70718954248366 0.309976936967545 0.487528899262967 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/85 81/18639 0.0123456790123457 2.70718954248366 0.309976936967545 0.487528899262967 GO:0033218 amide binding 2/85 247/18639 0.00809716599190283 1.77556561085973 0.311024123783838 0.487528899262967 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/85 82/18639 0.0121951219512195 2.67417503586801 0.313137404709638 0.487528899262967 GO:0033549 MAP kinase phosphatase activity 1/85 82/18639 0.0121951219512195 2.67417503586801 0.313137404709638 0.487528899262967 GO:0140272 exogenous protein binding 1/85 82/18639 0.0121951219512195 2.67417503586801 0.313137404709638 0.487528899262967 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/85 83/18639 0.0120481927710843 2.64195605953225 0.31628356629824 0.487528899262967 GO:0008135 translation factor activity, RNA binding 1/85 83/18639 0.0120481927710843 2.64195605953225 0.31628356629824 0.487528899262967 GO:0017018 myosin phosphatase activity 1/85 84/18639 0.0119047619047619 2.61050420168067 0.319415485724013 0.487528899262967 GO:0180051 translation factor activity 1/85 84/18639 0.0119047619047619 2.61050420168067 0.319415485724013 0.487528899262967 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/85 86/18639 0.0116279069767442 2.54979480164159 0.325636852636992 0.491847329503791 GO:0050660 flavin adenine dinucleotide binding 1/85 86/18639 0.0116279069767442 2.54979480164159 0.325636852636992 0.491847329503791 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/85 89/18639 0.0112359550561798 2.46384666226041 0.334863670357093 0.499901238151916 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/85 89/18639 0.0112359550561798 2.46384666226041 0.334863670357093 0.499901238151916 GO:0003730 mRNA 3'-UTR binding 2/85 262/18639 0.00763358778625954 1.67391109115402 0.33614048772284 0.499901238151916 GO:0140793 histone H2AXY142 phosphatase activity 1/85 90/18639 0.0111111111111111 2.43647058823529 0.3379114648595 0.499971044945178 GO:0072341 modified amino acid binding 1/85 91/18639 0.010989010989011 2.40969618616677 0.340945457284263 0.501899404124043 GO:0051219 phosphoprotein binding 1/85 93/18639 0.010752688172043 2.35787476280835 0.346972282678141 0.507449595613915 GO:0016410 N-acyltransferase activity 1/85 94/18639 0.0106382978723404 2.33279098873592 0.349965238354424 0.507449595613915 GO:0042562 hormone binding 1/85 94/18639 0.0106382978723404 2.33279098873592 0.349965238354424 0.507449595613915 GO:0004896 cytokine receptor activity 1/85 96/18639 0.0104166666666667 2.28419117647059 0.355910540401686 0.510960676814302 GO:0016407 acetyltransferase activity 1/85 96/18639 0.0104166666666667 2.28419117647059 0.355910540401686 0.510960676814302 GO:0004725 protein tyrosine phosphatase activity 1/85 98/18639 0.0102040816326531 2.237575030012 0.361802099884502 0.516860142692145 GO:0030246 carbohydrate binding 2/85 280/18639 0.00714285714285714 1.5663025210084 0.365926842217645 0.520076658996914 GO:0043130 ubiquitin binding 1/85 100/18639 0.01 2.19282352941176 0.367640396877129 0.520076658996914 GO:0035091 phosphatidylinositol binding 2/85 284/18639 0.00704225352112676 1.54424192212096 0.372481463171282 0.524367108347921 GO:0004722 protein serine/threonine phosphatase activity 1/85 103/18639 0.00970873786407767 2.12895488292404 0.376299014940974 0.527182194844842 GO:0003712 transcription coregulator activity 3/85 495/18639 0.00606060606060606 1.32898395721925 0.393681785514792 0.548883258650432 GO:0004222 metalloendopeptidase activity 1/85 110/18639 0.00909090909090909 1.99347593582888 0.396049452541224 0.549542302569162 GO:1902936 phosphatidylinositol bisphosphate binding 1/85 111/18639 0.00900900900900901 1.97551669316375 0.398820017414342 0.550751452619806 GO:0005200 structural constituent of cytoskeleton 1/85 112/18639 0.00892857142857143 1.9578781512605 0.40157802143635 0.551931877803515 GO:0001221 transcription coregulator binding 1/85 115/18639 0.00869565217391304 1.90680306905371 0.409777229871077 0.555305591881366 GO:0035401 histone H3Y41 kinase activity 1/85 115/18639 0.00869565217391304 1.90680306905371 0.409777229871077 0.555305591881366 GO:0140801 histone H2AXY142 kinase activity 1/85 115/18639 0.00869565217391304 1.90680306905371 0.409777229871077 0.555305591881366 GO:0032182 ubiquitin-like protein binding 1/85 120/18639 0.00833333333333333 1.82735294117647 0.423196563576379 0.570823271800697 GO:0015108 chloride transmembrane transporter activity 1/85 121/18639 0.00826446280991736 1.81225085075352 0.425844022515631 0.571735030229319 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/85 122/18639 0.00819672131147541 1.79739633558341 0.428479472244876 0.572622336179789 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/85 128/18639 0.0078125 1.71314338235294 0.444042975043998 0.590699370471373 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/85 132/18639 0.00757575757575758 1.66122994652406 0.454185188338149 0.601432441178371 GO:0015297 antiporter activity 1/85 135/18639 0.00740740740740741 1.6243137254902 0.461671650831623 0.608567176096231 GO:0140789 histone phosphatase activity 1/85 136/18639 0.00735294117647059 1.61237024221453 0.464144516681133 0.609058415554427 GO:0070851 growth factor receptor binding 1/85 139/18639 0.00719424460431655 1.5775708844689 0.471495957488797 0.615918142665546 GO:0004713 protein tyrosine kinase activity 1/85 140/18639 0.00714285714285714 1.5663025210084 0.473924219305741 0.6163140071689 GO:0141003 histone H2AX kinase activity 2/85 354/18639 0.00564971751412429 1.23888334995015 0.482028469199504 0.623213219707245 GO:0019955 cytokine binding 1/85 144/18639 0.00694444444444444 1.52279411764706 0.483527498048724 0.623213219707245 GO:0140996 histone H3 kinase activity 2/85 357/18639 0.00560224089635854 1.22847256549679 0.486468805189905 0.624229882765808 GO:0035173 histone kinase activity 2/85 360/18639 0.00555555555555556 1.21823529411765 0.490885953686154 0.627123024532972 GO:0008509 monoatomic anion transmembrane transporter activity 1/85 149/18639 0.00671140939597315 1.47169364390051 0.495288286983929 0.629971943970787 GO:0019842 vitamin binding 1/85 150/18639 0.00666666666666667 1.46188235294118 0.497608486854474 0.630159219160688 GO:0003774 cytoskeletal motor activity 1/85 153/18639 0.0065359477124183 1.43321799307958 0.504506028175324 0.636116296394974 GO:0005506 iron ion binding 1/85 154/18639 0.00649350649350649 1.42391138273491 0.506784346232507 0.636222772326524 GO:0140375 immune receptor activity 1/85 156/18639 0.00641025641025641 1.40565610859728 0.511309969266585 0.639137461583231 GO:0015631 tubulin binding 2/85 385/18639 0.00519480519480519 1.13912910618793 0.52676962065263 0.655636008537609 GO:0015103 inorganic anion transmembrane transporter activity 1/85 165/18639 0.00606060606060606 1.32898395721925 0.531172660664369 0.658290904242167 GO:0005201 extracellular matrix structural constituent 1/85 168/18639 0.00595238095238095 1.30525210084034 0.537614588039053 0.663439278856704 GO:0004721 phosphoprotein phosphatase activity 1/85 175/18639 0.00571428571428571 1.25304201680672 0.552307547398325 0.678683003158959 GO:0008237 metallopeptidase activity 1/85 184/18639 0.00543478260869565 1.19175191815857 0.570522286639891 0.697745463947942 GO:0031406 carboxylic acid binding 1/85 187/18639 0.0053475935828877 1.17263290342875 0.576429577847942 0.697745463947942 GO:0046943 carboxylic acid transmembrane transporter activity 1/85 188/18639 0.00531914893617021 1.16639549436796 0.578380774785018 0.697745463947942 GO:0005342 organic acid transmembrane transporter activity 1/85 189/18639 0.00529100529100529 1.16022408963585 0.580323088705308 0.697745463947942 GO:0043177 organic acid binding 1/85 189/18639 0.00529100529100529 1.16022408963585 0.580323088705308 0.697745463947942 GO:0019902 phosphatase binding 1/85 190/18639 0.00526315789473684 1.15411764705882 0.582256559570352 0.697745463947942 GO:0003779 actin binding 2/85 443/18639 0.00451467268623025 0.989988049395831 0.603346136530143 0.720042714377537 GO:0005516 calmodulin binding 1/85 207/18639 0.00483091787439614 1.05933503836317 0.6138104509638 0.722925016979449 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/85 229/18639 0.00436681222707424 0.957564860005137 0.651171095655853 0.722925016979449 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 2/85 484/18639 0.00413223140495868 0.906125425376762 0.651698267997551 0.722925016979449 GO:0001216 DNA-binding transcription activator activity 2/85 491/18639 0.00407331975560081 0.893207140289924 0.659477077014235 0.722925016979449 GO:0005543 phospholipid binding 2/85 497/18639 0.00402414486921529 0.882423955497692 0.666035269683934 0.722925016979449 GO:0005539 glycosaminoglycan binding 1/85 242/18639 0.00413223140495868 0.906125425376762 0.671544561232089 0.722925016979449 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/85 243/18639 0.00411522633744856 0.90239651416122 0.673062129982172 0.722925016979449 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0004711 ribosomal protein S6 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0035175 histone H3S10 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0035979 histone H2AXS139 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0044022 histone H3S28 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0044023 histone H4S1 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0044024 histone H2AS1 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0044025 histone H2BS14 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0072354 histone H3T3 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0072371 histone H2AS121 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0140823 histone H2BS36 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0140855 histone H3S57 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0140995 histone H2A kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0140997 histone H4 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0140998 histone H2B kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:1990244 histone H2AT120 kinase activity 1/85 245/18639 0.00408163265306122 0.895030012004802 0.67607651013606 0.722925016979449 GO:0004677 DNA-dependent protein kinase activity 1/85 246/18639 0.0040650406504065 0.891391678622669 0.677573383933952 0.722925016979449 GO:0140857 histone H3T45 kinase activity 1/85 246/18639 0.0040650406504065 0.891391678622669 0.677573383933952 0.722925016979449 GO:0035402 histone H3T11 kinase activity 1/85 247/18639 0.00404858299595142 0.887782805429864 0.679063421576839 0.722925016979449 GO:0035403 histone H3T6 kinase activity 1/85 247/18639 0.00404858299595142 0.887782805429864 0.679063421576839 0.722925016979449 GO:0042393 histone binding 1/85 247/18639 0.00404858299595142 0.887782805429864 0.679063421576839 0.722925016979449 GO:0004679 AMP-activated protein kinase activity 1/85 248/18639 0.00403225806451613 0.884203036053131 0.680546653915136 0.722925016979449 GO:0008514 organic anion transmembrane transporter activity 1/85 269/18639 0.00371747211895911 0.815176033238574 0.710175707511641 0.751645821818891 GO:0016791 phosphatase activity 1/85 273/18639 0.00366300366300366 0.803232062055591 0.715503218020195 0.754530666275842 GO:0008017 microtubule binding 1/85 276/18639 0.0036231884057971 0.794501278772379 0.719435231347666 0.755928322792837 GO:0031267 small GTPase binding 1/85 283/18639 0.00353356890459364 0.774849303679069 0.728402295111458 0.762587240369397 GO:0015291 secondary active transmembrane transporter activity 1/85 287/18639 0.00348432055749129 0.764050010248002 0.733398548543115 0.765056039847135 GO:0001664 G protein-coupled receptor binding 1/85 297/18639 0.00336700336700337 0.738324420677362 0.745495283735957 0.774887570908342 GO:0051020 GTPase binding 1/85 315/18639 0.00317460317460317 0.696134453781513 0.765917992244225 0.793272206252947 GO:0003924 GTPase activity 1/85 331/18639 0.00302114803625378 0.662484449973343 0.782706559916959 0.807775453295082 GO:0045182 translation regulator activity 1/85 356/18639 0.00280898876404494 0.615961665565102 0.806586102327566 0.829467977570901 GO:0106310 protein serine kinase activity 1/85 361/18639 0.00277008310249307 0.607430340557276 0.811041003281275 0.829966147673883 GO:0042578 phosphoric ester hydrolase activity 1/85 363/18639 0.00275482093663912 0.604083616917842 0.812794434273734 0.829966147673883 GO:0046982 protein heterodimerization activity 1/85 369/18639 0.002710027100271 0.594261119081779 0.817958821917573 0.832308976688057 GO:0005525 GTP binding 1/85 378/18639 0.00264550264550265 0.580112044817927 0.825442522030436 0.836987172688205 GO:0019001 guanyl nucleotide binding 1/85 400/18639 0.0025 0.548205882352941 0.842480105258884 0.848330661545404 GO:0032561 guanyl ribonucleotide binding 1/85 400/18639 0.0025 0.548205882352941 0.842480105258884 0.848330661545404 GO:0004674 protein serine/threonine kinase activity 1/85 433/18639 0.0023094688221709 0.506425757369923 0.865001285389276 0.867994369421764 GO:0022804 active transmembrane transporter activity 1/85 457/18639 0.00218818380743982 0.479830093963187 0.879351576529514 0.879351576529514