category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 7/19 298/9376 11.5916637230661 CSH1/LEP/EBI3/GDF15/INHBA/CSH2/GH2 8.37281220724963 NA NA hsa04081 Hormone signaling 5/19 219/9376 11.26652247056 CSH1/CGA/LEP/CSH2/GH2 6.92728309714578 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 6/19 370/9376 8.0022759601707 CSH1/CGA/KISS1/LEP/CSH2/GH2 6.19253167935356 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 3/19 52/9376 28.4696356275304 CGA/CYP11A1/CYP19A1 8.95050546491152 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 4/19 168/9376 11.749373433584 CSH1/LEP/CSH2/GH2 6.33503852147359 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 3/19 122/9376 12.1345987920621 CSH1/CSH2/GH2 5.57806877496285 Organismal Systems Endocrine system hsa04929 GnRH secretion 2/19 65/9376 15.1838056680162 CGA/KISS1 5.17065321253428 Metabolism Lipid metabolism hsa00140 Steroid hormone biosynthesis 2/19 66/9376 14.9537480063796 CYP11A1/CYP19A1 5.12604160675079 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 2/19 75/9376 13.159298245614 GADD45G/SERPINE1 4.76396370954183 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 3/19 362/9376 4.08956091887176 CSH1/CSH2/GH2 2.70138444772834 Cellular Processes Cell growth and death hsa04218 Cellular senescence 2/19 157/9376 6.28628897083473 GADD45G/SERPINE1 3.00990606770183 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 2/19 201/9376 4.91018591254255 GADD45G/AFF1 2.52514617152456 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 1/19 37/9376 13.3371266002845 GADD45G 3.38812028025418 Metabolism Lipid metabolism hsa00071 Fatty acid degradation 1/19 43/9376 11.4761321909425 ACADVL 3.10254928159801 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/19 54/9376 9.13840155945419 CGA 2.70256139815532 Metabolism Global and overview maps hsa01212 Fatty acid metabolism 1/19 57/9376 8.65743305632502 ACADVL 2.61294401524763 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 1/19 59/9376 8.36396074933096 CGA 2.55678109837479 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/19 59/9376 8.36396074933096 GADD45G 2.55678109837479 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 1/19 63/9376 7.83291562238931 GADD45G 2.45202929765807 Organismal Systems Endocrine system hsa04927 Cortisol synthesis and secretion 1/19 65/9376 7.5919028340081 CYP11A1 2.40305347966213 Metabolism Metabolism of cofactors and vitamins hsa00830 Retinol metabolism 1/19 68/9376 7.25696594427245 RDH13 2.33337308558764 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 1/19 70/9376 7.04962406015038 LEP 2.28923304925432 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/19 71/9376 6.95033358042995 CGA 2.26780873040109 Human Diseases Cancer: specific types hsa05218 Melanoma 1/19 73/9376 6.75991348233598 GADD45G 2.22617859996441 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 1/19 73/9376 6.75991348233598 GADD45G 2.22617859996441 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/19 75/9376 6.57964912280702 CGA 2.18608388379795 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/19 76/9376 6.49307479224377 PLIN2 2.16658113895086 Human Diseases Cancer: specific types hsa05214 Glioma 1/19 76/9376 6.49307479224377 GADD45G 2.16658113895086 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/19 77/9376 6.40874914559125 GADD45G 2.14742597644638 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 1/19 77/9376 6.40874914559125 GADD45G 2.14742597644638 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/19 87/9376 5.67211131276467 GADD45G 1.97279723279168 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/19 88/9376 5.60765550239234 SERPINE1 1.95683567630628 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 1/19 93/9376 5.30616864742501 CGA 1.88053948935344 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/19 93/9376 5.30616864742501 GADD45G 1.88053948935344 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 1/19 98/9376 5.03544575725027 CYP11A1 1.80955376704998 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/19 99/9376 4.9845826687932 KRT19 1.79593570428066 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 1/19 101/9376 4.88587806149036 SERPINE1 1.76924110177362 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/19 103/9376 4.79100664282064 SERPINE1 1.74323987654735 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/19 105/9376 4.69974937343358 GADD45G 1.71789963827157 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/19 109/9376 4.52728150651859 EBI3 1.66908291930711 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 1/19 110/9376 4.48612440191388 SERPINE1 1.65724683920097 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/19 110/9376 4.48612440191388 INHBA 1.65724683920097 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/19 122/9376 4.04486626402071 LEP 1.52537812528818 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/19 133/9376 3.71032845271072 GADD45G 1.41851976748277 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/19 137/9376 3.60199769496735 GADD45G 1.38244808567932 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/19 139/9376 3.55017039000379 KRT19 1.36491388287924 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/19 140/9376 3.52481203007519 SERPINE1 1.35626711129992 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 1/19 144/9376 3.42690058479532 INHBA 1.32245060125788 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/19 144/9376 3.42690058479532 ACADVL 1.32245060125788 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/19 148/9376 3.33428165007112 GADD45G 1.28980615401819 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/19 150/9376 3.28982456140351 GADD45G 1.27389970714416 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/19 154/9376 3.20437457279563 RDH13 1.24287461605075 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 1/19 155/9376 3.18370118845501 CYP11A1 1.23527648016523 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/19 157/9376 3.14314448541736 SERPINE1 1.22026314229297 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 1/19 157/9376 3.14314448541736 LEP 1.22026314229297 Cellular Processes Cell growth and death hsa04110 Cell cycle 1/19 158/9376 3.12325116588941 GADD45G 1.21284607407471 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/19 170/9376 2.90278637770898 GADD45G 1.12816632694913 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 1/19 174/9376 2.83605565638234 DERL3 1.10157348905301 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/19 205/9376 2.40718870346598 GADD45G 0.917941591131371 NA NA hsa04382 Cornified envelope formation 1/19 217/9376 2.27407227746786 KRT19 0.855645808727713 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 1/19 226/9376 2.18351187703773 CGA 0.811540909017803 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/19 300/9376 1.64491228070175 GADD45G 0.511573635717742 NA NA hsa04519 Cadherin signaling 1/19 404/9376 1.22146951537259 KRT19 0.205047335102602