category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 5/15 370/9376 8.44684684684685 CGA/CSH1/LEP/KISS1/CRH 5.85029085281765 NA NA hsa04081 Hormone signaling 4/15 219/9376 11.4167427701674 CGA/CSH1/LEP/CRH 6.24377918115716 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 4/15 298/9376 8.39015659955257 CSH1/LEP/GDF15/INHBA 5.18963518345746 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 2/15 52/9376 24.0410256410256 CGA/CYP19A1 6.6691808080686 Organismal Systems Endocrine system hsa04929 GnRH secretion 2/15 65/9376 19.2328205128205 CGA/KISS1 5.90449170509103 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 2/15 168/9376 7.44126984126984 CSH1/LEP 3.37220232824776 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 2/15 201/9376 6.2195688225539 FLT1/GADD45G 2.99433071842303 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 2/15 226/9376 5.53156342182891 CGA/CRH 2.76033555978204 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 1/15 37/9376 16.8936936936937 GADD45G 3.8774451085426 Cellular Processes Cell growth and death hsa04216 Ferroptosis 1/15 42/9376 14.8825396825397 FTL 3.60935679651142 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/15 46/9376 13.5884057971014 FTL 3.42593385214979 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 2/15 300/9376 4.16711111111111 FLT1/GADD45G 2.23175660499163 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/15 54/9376 11.5753086419753 CGA 3.11964751853012 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 1/15 59/9376 10.5943502824859 CGA 2.95919560549513 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/15 59/9376 10.5943502824859 GADD45G 2.95919560549513 Organismal Systems Nervous system hsa04730 Long-term depression 1/15 60/9376 10.4177777777778 CRH 2.92940534046301 Organismal Systems Digestive system hsa04978 Mineral absorption 1/15 61/9376 10.2469945355191 FTL 2.90030875771398 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 1/15 63/9376 9.92169312169312 GADD45G 2.84408714350695 Metabolism Lipid metabolism hsa00140 Steroid hormone biosynthesis 1/15 66/9376 9.47070707070707 CYP19A1 2.76431121588939 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 1/15 70/9376 8.92952380952381 LEP 2.66553720378822 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/15 71/9376 8.8037558685446 CGA 2.64207295343403 Human Diseases Cancer: specific types hsa05218 Melanoma 1/15 73/9376 8.56255707762557 GADD45G 2.59650241073535 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 1/15 73/9376 8.56255707762557 GADD45G 2.59650241073535 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 2/15 362/9376 3.45340699815838 CSH1/FLT1 1.9056153973071 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/15 75/9376 8.33422222222222 GADD45G 2.55264263855469 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/15 75/9376 8.33422222222222 CGA 2.55264263855469 Human Diseases Cancer: specific types hsa05214 Glioma 1/15 76/9376 8.22456140350877 GADD45G 2.5313194350217 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/15 77/9376 8.11774891774892 GADD45G 2.51038336155545 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 1/15 77/9376 8.11774891774892 GADD45G 2.51038336155545 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/15 87/9376 7.18467432950192 GADD45G 2.31986186390581 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 1/15 93/9376 6.72114695340502 CGA 2.2194764811702 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/15 93/9376 6.72114695340502 GADD45G 2.2194764811702 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/15 95/9376 6.57964912280702 FLT1 2.18797044125199 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/15 105/9376 5.95301587301587 GADD45G 2.0430134410493 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 1/15 110/9376 5.68242424242424 FLT1 1.97738438066442 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/15 110/9376 5.68242424242424 INHBA 1.97738438066442 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/15 110/9376 5.68242424242424 SPDYE2 1.97738438066442 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/15 122/9376 5.12349726775956 LEP 1.83506319133143 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/15 122/9376 5.12349726775956 CSH1 1.83506319133143 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/15 133/9376 4.69974937343358 GADD45G 1.72013207593074 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/15 137/9376 4.5625304136253 GADD45G 1.68142122673369 Cellular Processes Cell growth and death hsa04114 Oocyte meiosis 1/15 138/9376 4.52946859903382 SPDYE2 1.67197597152821 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 1/15 142/9376 4.4018779342723 RHOBTB1 1.63507661945507 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 1/15 144/9376 4.34074074074074 INHBA 1.61713496234044 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/15 148/9376 4.22342342342342 GADD45G 1.5822116112972 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/15 150/9376 4.16711111111111 GADD45G 1.56520904670524 NA NA hsa04518 Integrin signaling 1/15 154/9376 4.05887445887446 FLT1 1.53207349669441 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 1/15 155/9376 4.03268817204301 CRH 1.52396411465387 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/15 157/9376 3.98131634819533 GADD45G 1.50794716594443 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 1/15 157/9376 3.98131634819533 LEP 1.50794716594443 Cellular Processes Cell growth and death hsa04110 Cell cycle 1/15 158/9376 3.95611814345992 GADD45G 1.50003752548621 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/15 168/9376 3.72063492063492 FTL 1.42433582814605 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/15 170/9376 3.67686274509804 GADD45G 1.40988997994127 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/15 173/9376 3.6131021194605 TMPRSS4 1.38862464212098 Human Diseases Substance dependence hsa05034 Alcoholism 1/15 191/9376 3.27260034904014 CRH 1.27019476194038 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/15 203/9376 3.07914614121511 FLT1 1.19880206911903 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/15 205/9376 3.04910569105691 GADD45G 1.1874165244736 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/15 212/9376 2.94842767295597 FLT1 1.14862912558984 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/15 238/9376 2.62633053221288 FLT1 1.01728317608461 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/15 254/9376 2.46089238845144 FLT1 0.944844187649481 NA NA hsa04517 IgSF CAM signaling 1/15 299/9376 2.09052396878484 CABLES1 0.767131448507397