category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	7/86	139/9376	5.4903797891919	FOS/KRT19/HSPA1B/PIK3CB/SOS2/HSPA8/KRT23	5.13159070288981
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	10/86	300/9376	3.63410852713178	GADD45G/FOS/DUSP1/FLT1/HSPA1B/MAP3K13/SOS2/HSPA8/HSPB1/BRAF	4.46142970756201
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	5/86	77/9376	7.07943219571126	GADD45G/PIK3CB/SOS2/GAB2/BRAF	5.15367781215955
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	5/86	87/9376	6.26570435712376	GADD45G/FOS/PIK3CB/SOS2/BRAF	4.74743058844721
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	6/86	142/9376	4.60661644284311	FOS/JUNB/PIK3CB/MITF/FOSB/GAB2	4.16654620444074
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	4/86	59/9376	7.39140717382736	GADD45G/PIK3CB/SOS2/BRAF	4.73817885944229
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	4/86	62/9376	7.0337584396099	HSPA1B/PIK3CB/CRYAB/HSPA8	4.58609085269285
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	4/86	70/9376	6.22990033222591	PIK3CB/EPAS1/SOS2/BRAF	4.22559544000218
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	4/86	71/9376	6.14215525712414	CGA/FOS/PIK3CB/SOS2	4.18449619812926
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	6/86	168/9376	3.8936877076412	LEP/CSH1/CSF2RB/PIK3CB/SOS2/OSMR	3.64125129248015
Human Diseases	Cancer: specific types	hsa05218	Melanoma	4/86	73/9376	5.97387703090156	GADD45G/PIK3CB/MITF/BRAF	4.10461067615536
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	4/86	73/9376	5.97387703090156	GADD45G/PIK3CB/SOS2/BRAF	4.10461067615536
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	5/86	119/9376	4.58080906781317	FOS/JUNB/PIK3CB/CXCL1/TNFRSF1B	3.78221767890769
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	4/86	76/9376	5.73806609547124	PLIN2/ANGPTL4/HMGCS2/UBC	3.99018878345755
Human Diseases	Cancer: specific types	hsa05214	Glioma	4/86	76/9376	5.73806609547124	GADD45G/PIK3CB/SOS2/BRAF	3.99018878345755
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	5/86	122/9376	4.46816622188334	FOS/JUNB/CSH1/PIK3CB/SOS2	3.70972809149192
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	6/86	174/9376	3.75942261427426	HSPA1B/MAN1C1/CRYAB/HSPA8/PPP1R15A/HERPUD1	3.53491304947454
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	8/86	298/9376	2.92679881379741	LEP/EBI3/CSH1/CSF2RB/INHBA/CXCL1/TNFRSF1B/OSMR	3.25219381795544
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	5/86	133/9376	4.09861863962231	GADD45G/PIK3CB/SOS2/BCL6/BRAF	3.46269691335915
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	5/86	144/9376	3.78552971576227	PIK3CB/INHBA/DLX5/ID3/KLF4	3.24091880533282
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	6/86	204/9376	3.20656634746922	HSPG2/PIK3CB/EZR/SOS2/TIMP3/BRAF	3.06568167528252
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	5/86	148/9376	3.68321810182275	GADD45G/FOS/PIK3CB/SOS2/BRAF	3.16562922561398
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	4/86	99/9376	4.40498003288701	FOS/PIK3CB/SOS2/BRAF	3.27684119942406
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	6/86	216/9376	3.02842377260982	FOS/HSPA1B/PIK3CB/CXCL1/HSPA8/ABCA1	2.90178236669507
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	3/86	56/9376	5.84053156146179	HSPA1B/CXCL1/HSPA8	3.49547435586971
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	5/86	163/9376	3.34427165073477	FOS/HSPG2/PIK3CB/SOS2/BRAF	2.90488008447789
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	4/86	110/9376	3.96448202959831	FLT1/PIK3CB/EPAS1/SERPINE1	3.00902657615617
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	3/86	68/9376	4.80984952120383	PIK3CB/SOS2/BRAF	3.03361943801239
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	3/86	69/9376	4.74014155712841	PIK3CB/SOS2/GAB2	3.00009311961375
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	6/86	250/9376	2.61655813953488	HSPA1B/DAB2/HSPA8/PRKCZ/PIP5KL1/RNF103-CHMP3	2.49257426967798
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	4/86	125/9376	3.48874418604651	PIK3CB/PRKCZ/GAB2/ACER2	2.69505685390566
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	4/86	130/9376	3.35456171735242	FOS/PIK3CB/SOS2/PRKCZ	2.60094888303949
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	5/86	193/9376	2.82443667911797	PIK3CB/CXCL1/SOS2/PRKCZ/BRAF	2.46400828651111
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	3/86	77/9376	4.24765931742676	GADD45G/PIK3CB/BRAF	2.75311726932047
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/86	136/9376	3.20656634746922	FOS/HSPA1B/PIK3CB/HSPA8	2.49389098792132
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/86	80/9376	4.08837209302326	PIK3CB/SOS2/BRAF	2.66903065726983
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/86	137/9376	3.18316075369207	GADD45G/FOS/CSF2RB/PIK3CB	2.47662653856146
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	4/86	138/9376	3.16009437141894	PIK3CB/SOS2/PRKCZ/BRAF	2.4595196482507
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	5/86	203/9376	2.68530186733876	FLT1/FLNB/PIK3CB/SOS2/BRAF	2.33559227967715
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	4/86	142/9376	3.07107762856207	FOS/DUSP1/PIK3CB/PRKCZ	2.39261389979827
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	3/86	86/9376	3.80313683071931	PIK3CB/SOS2/BRAF	2.51253819853719
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	5/86	212/9376	2.57130320315928	FLT1/PIK3CB/PRKD3/PRKCZ/BRAF	2.22644716169537
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/86	37/9376	5.89314896291641	GADD45G/BRAF	2.86923499030688
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	4/86	150/9376	2.90728682170543	GADD45G/PIK3CB/SOS2/BRAF	2.26559313092099
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	5/86	217/9376	2.51205658557497	FOS/PIK3CB/SOS2/BCL6/KLF4	2.16820772931057
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/86	91/9376	3.59417326859187	FOS/PIK3CB/SOS2	2.39252083693831
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/86	94/9376	3.47946561108362	FOS/CXCL1/FOSB	2.3244929899791
NA	NA	hsa04517	IgSF CAM signaling	6/86	299/9376	2.18775764175157	PIK3CB/EZR/NLGN1/NECTIN4/LRFN5/NLGN4X	2.00825689407561
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/86	95/9376	3.44283965728274	FOS/FLT1/CXCL1	2.30242973242763
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	4/86	158/9376	2.76008242566971	PIK3CB/CASTOR2/SOS2/BRAF	2.14669430901523
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	5/86	227/9376	2.40139329986682	FOS/PIK3CB/SOS2/PRKD3/BRAF	2.05642634215572
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	3/86	99/9376	3.30373502466526	FOS/PIK3CB/SOS2	2.21703909229056
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/86	101/9376	3.23831452912733	PIK3CB/PRKCZ/SERPINE1	2.17596471343775
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/86	103/9376	3.17543463535787	FOS/PIK3CB/SERPINE1	2.13590301110737
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	3/86	103/9376	3.17543463535787	PIK3CB/CXCL1/HSPB1	2.13590301110737
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	2/86	47/9376	4.63928748144483	PIK3CB/PRKCZ	2.40643842058879
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	4/86	170/9376	2.56525307797538	GADD45G/PIK3CB/SOS2/BRAF	1.98152952935526
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	3/86	106/9376	3.08556384379114	PIK3CB/SOS2/BRAF	2.07760777318899
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	3/86	110/9376	2.97336152219873	SPDYE2/PIK3CB/BRAF	2.00301341191283
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/86	52/9376	4.19320214669052	CGA/HSD3B1	2.22153908656964
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	2/86	52/9376	4.19320214669052	ANGPTL4/ABCA1	2.22153908656964
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	3/86	115/9376	2.84408493427705	FOS/GCM1/BRAF	1.91437892545017
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	2/86	56/9376	3.8936877076412	MAN1C1/MGAT3	2.08960752502575
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/86	120/9376	2.72558139534884	PIK3CB/SOS2/BRAF	1.8303806104427
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/86	122/9376	2.68089973313	FOS/PIK3CB/SOS2	1.79797638291611
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/86	59/9376	3.69570358691368	CGA/PIK3CB	1.99842153683169
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/86	60/9376	3.63410852713178	PIK3CB/HSPB1	1.96934387348205
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	1/86	12/9376	9.08527131782946	NECTIN4	2.69638265916403
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/86	196/9376	2.2249644043664	FOS/PIK3CB/CXCL1/UBC	1.66746670462103
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	4/86	201/9376	2.16961703112345	GADD45G/FLT1/MITF/BCL6	1.61274492013817
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/86	65/9376	3.35456171735242	CGA/PIK3CB	1.83271781057835
Metabolism	Glycan biosynthesis and metabolism	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/86	14/9376	7.78737541528239	ST3GAL1	2.44516728935053
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	3/86	133/9376	2.45917118377339	PIK3CB/SOS2/BRAF	1.63061936357892
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/86	15/9376	7.26821705426357	ST3GAL1	2.33752110344648
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	2/86	69/9376	3.16009437141894	FOS/FOSB	1.73268422128544
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/86	70/9376	3.11495016611296	LEP/TNFRSF1B	1.70881340179481
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/86	16/9376	6.81395348837209	ST3GAL1	2.2393430378925
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	3/86	142/9376	2.30330822142155	MID1/RHOBTB1/UBC	1.50564774747704
NA	NA	hsa04081	Hormone signaling	4/86	219/9376	1.99129234363385	CGA/LEP/CSH1/PIK3CB	1.42815126540514
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/86	75/9376	2.90728682170543	GADD45G/SERPINE1	1.59554414415698
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	4/86	226/9376	1.92961514714962	CGA/FOS/PIK3CB/BRAF	1.36104934493331
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	3/86	149/9376	2.19509911034806	PIK3CB/SOS2/GAB2	1.41479593663018
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/86	78/9376	2.79546809779368	PIK3CB/PIP5KL1	1.53199458469869
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/86	232/9376	1.87971130713713	PIK3CB/EZR/SOS2/BRAF	1.30539836578925
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	4/86	233/9376	1.87164387663439	HSPG2/COL27A1/DMD/SDC3	1.29628259842144
NA	NA	hsa04518	Integrin signaling	3/86	154/9376	2.12382965871338	FLT1/FLNB/PIK3CB	1.35292990840087
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	3/86	156/9376	2.09660107334526	PIK3CB/SOS2/BRAF	1.32883944794791
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/86	82/9376	2.65910380034033	HSPA1B/HSPA8	1.45179787725402
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/86	157/9376	2.08324692638128	GADD45G/PIK3CB/SERPINE1	1.31692908986797
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/86	157/9376	2.08324692638128	LEP/FOS/PIK3CB	1.31692908986797
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/86	238/9376	1.83232362712527	FLT1/PIK3CB/SOS2/GAB2	1.25135960540021
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/86	160/9376	2.04418604651163	NLGN1/SDC3/NLGN4X	1.28172144442027
Metabolism	Metabolism of terpenoids and polyketides	hsa00900	Terpenoid backbone biosynthesis	1/86	23/9376	4.74014155712841	HMGCS2	1.7278398947691
Metabolism	Glycan biosynthesis and metabolism	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/86	24/9376	4.54263565891473	EXT1	1.67188679791251
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/86	90/9376	2.42273901808786	FOS/PIK3CB	1.30484571560581
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/86	93/9376	2.34458614653663	CGA/SOS2	1.25375575119968
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/86	93/9376	2.34458614653663	GADD45G/PIK3CB	1.25375575119968
Metabolism	Carbohydrate metabolism	hsa00650	Butanoate metabolism	1/86	27/9376	4.03789836347976	HMGCS2	1.52089610945243
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/86	27/9376	4.03789836347976	TECR	1.52089610945243
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/86	98/9376	2.2249644043664	PIK3CB/GAB2	1.17283341130286
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/86	98/9376	2.2249644043664	PRKD3/HSD3B1	1.17283341130286
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/86	28/9376	3.8936877076412	TECR	1.47536110533316
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/86	99/9376	2.2024900164435	KRT19/KRT23	1.15723698515707
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/86	100/9376	2.18046511627907	CXCL1/TNFRSF1B	1.14182564974388
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/86	362/9376	1.50584607477836	FLT1/CSH1/PIK3CB/SOS2/OSMR	0.944367210703589
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/86	105/9376	2.0766334440753	GADD45G/CXCL1	1.06739762524477
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/86	105/9376	2.0766334440753	MITF/UBC	1.06739762524477
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	5/86	370/9376	1.4732872407291	CGA/LEP/ADM/CSH1/P2RY14	0.893689579596852
Human Diseases	Substance dependence	hsa05034	Alcoholism	3/86	191/9376	1.71240715938147	SOS2/FOSB/BRAF	0.957045058934804
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/86	109/9376	2.00042671218263	FOS/PIK3CB	1.01077840206113
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/86	109/9376	2.00042671218263	FOS/EBI3	1.01077840206113
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/86	109/9376	2.00042671218263	PIK3CB/PRKCZ	1.01077840206113
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/86	110/9376	1.98224101479915	INHBA/ID3	0.99700024766949
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/86	34/9376	3.20656634746922	BHLHE40	1.24011946509473
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/86	112/9376	1.9468438538206	HSPA1B/HSPA8	0.969873536140714
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/86	36/9376	3.02842377260982	ST3GAL1	1.17317692090779
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/86	115/9376	1.89605662285136	FOS/PIK3CB	0.930213073656072
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/86	115/9376	1.89605662285136	DUSP1/BRAF	0.930213073656072
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/86	116/9376	1.87971130713713	PIK3CB/EZR	0.917256255406865
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/86	38/9376	2.86903304773562	PIK3CB	1.11073089222603
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	2/86	122/9376	1.78726648875334	LEP/PIK3CB	0.842100528628208
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/86	214/9376	1.52836339926103	FOS/PIK3CB/TNFRSF1B	0.752266072415965
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/86	41/9376	2.65910380034033	BRAF	1.02431924453876
NA	NA	hsa04382	Cornified envelope formation	3/86	217/9376	1.50723395134498	KRT19/TCHH/KRT23	0.727346174982416
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/86	42/9376	2.59579180509413	KMO	0.997226898281317
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/86	42/9376	2.59579180509413	SAT1	0.997226898281317
Organismal Systems	Immune system	hsa04611	Platelet activation	2/86	126/9376	1.73052787006275	PIK3CB/PRKCZ	0.794288367343363
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/86	43/9376	2.53542455381287	ABCA1	0.970910243435366
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/86	44/9376	2.47780126849894	MAN1C1	0.945326897309138
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/86	44/9376	2.47780126849894	GTF2I	0.945326897309138
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/86	45/9376	2.42273901808786	ABCA1	0.920437726505658
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	4/86	323/9376	1.35013319893441	PIK3CB/EZR/SOS2/TIMP3	0.616119989667158
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/86	134/9376	1.62721277334259	ADM/BRAF	0.703576488563772
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/86	48/9376	2.27131782945736	HMGCS2	0.849586288210574
NA	NA	hsa03272	Virion - Hepatitis viruses	1/86	48/9376	2.27131782945736	HSPG2	0.849586288210574
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/86	48/9376	2.27131782945736	PIK3CB	0.849586288210574
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/86	138/9376	1.58004718570947	FOS/PIK3CB	0.660451445567085
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/86	49/9376	2.2249644043664	FOSB	0.827137150471407
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/86	50/9376	2.18046511627907	SAT1	0.805225391610308
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/86	54/9376	2.01894918173988	CGA	0.722473400737429
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/86	55/9376	1.98224101479915	ACER2	0.702902620326413
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/86	248/9376	1.31882970742686	SNX9/FOS/PIK3CB	0.489580162536159
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/86	57/9376	1.91268869849041	TECR	0.664970610944415
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/86	154/9376	1.41588643914225	KMO/RDH13	0.500667692520291
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/86	155/9376	1.40675168792198	HSD3B1/BRAF	0.491284665550623
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/86	59/9376	1.84785179345684	UCK2	0.628542875526388
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/86	59/9376	1.84785179345684	PRDX6	0.628542875526388
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/86	157/9376	1.38883128425418	PRKCZ/SERPINE1	0.472711453699362
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/86	60/9376	1.81705426356589	BRAF	0.610855927795784
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/86	63/9376	1.73052787006275	GADD45G	0.559743770911528
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/86	65/9376	1.67728085867621	HSD3B1	0.52717441352755
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/86	66/9376	1.65186751233263	HSD3B1	0.511309040256771
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/86	169/9376	1.29021604513554	PIK3CB/UBC	0.366296447830021
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/86	67/9376	1.62721277334259	BRAF	0.49571012241764
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/86	170/9376	1.28262653898769	EZR/PRKCZ	0.357790596718053
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	3/86	275/9376	1.18934460887949	HSPA1B/PIK3CB/HSPA8	0.306620890586803
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/86	68/9376	1.60328317373461	RDH13	0.480368463972518
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/86	70/9376	1.55747508305648	DMD	0.450422382691123
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/86	71/9376	1.53553881428104	CXCL1	0.43580172520169
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/86	71/9376	1.53553881428104	PIK3CB	0.43580172520169
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	2/86	180/9376	1.21136950904393	PIK3CB/PILRB	0.275490176151999
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/86	75/9376	1.45364341085271	PIK3CB	0.379496192960765
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/86	75/9376	1.45364341085271	CGA	0.379496192960765
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/86	76/9376	1.43451652386781	EZR	0.365930513595306
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/86	184/9376	1.1850353892821	PIK3CB/PRKCZ	0.243885347333346
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/86	78/9376	1.39773404889684	PIK3CB	0.33936910926404
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/86	78/9376	1.39773404889684	FOS	0.33936910926404
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/86	78/9376	1.39773404889684	FOS	0.33936910926404
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/86	82/9376	1.32955190017016	UCK2	0.288374210832337
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/86	83/9376	1.31353320257775	BCORL1	0.276039748476123
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/86	85/9376	1.28262653898769	UCK2	0.251836212922894
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/86	86/9376	1.26771227690644	DMD	0.239958789943259
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	2/86	200/9376	1.09023255813953	FOS/EZR	0.124101940470659
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/86	88/9376	1.23890063424947	SERPINE1	0.216632964225696
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/86	89/9376	1.22498040240397	HSPG2	0.205177142261532
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/86	89/9376	1.22498040240397	SOS2	0.205177142261532
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/86	205/9376	1.06364152013613	GADD45G/PIK3CB	0.088641303780401
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/86	205/9376	1.06364152013613	PIK3CB/PRKCZ	0.088641303780401
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/86	90/9376	1.21136950904393	PIK3CB	0.193854666793598
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/86	93/9376	1.17229307326832	NECTIN4	0.160654214725048
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/86	93/9376	1.17229307326832	FOS	0.160654214725048
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/86	97/9376	1.1239510908655	FOS	0.118062680665174
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/86	333/9376	0.982191493819401	PIK3CB/SOS2/PRKCZ	-0.0318361358694949
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/86	98/9376	1.1124822021832	PIK3CB	0.107695280309484
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/86	99/9376	1.10124500822175	PIK3CB	0.0974348780235784
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/86	99/9376	1.10124500822175	DMD	0.0974348780235784
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/86	101/9376	1.07943817637578	MITF	0.0772253704491331
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/86	224/9376	0.973421926910299	FOS/PIK3CB	-0.0387361542655456
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/86	103/9376	1.05847821178596	COL27A1	0.0574155557734104
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/86	227/9376	0.960557319946727	PIK3CB/SOS2	-0.0578788026705133
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/86	105/9376	1.03831672203765	PIK3CB	0.0379880249264236
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/86	105/9376	1.03831672203765	DMD	0.0379880249264236
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/86	238/9376	0.916161813562634	FOS/PIK3CB	-0.126046788146675
Genetic Information Processing	Transcription	hsa03040	Spliceosome	2/86	243/9376	0.897310747439947	HSPA1B/HSPA8	-0.156044479021903
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/86	116/9376	0.939855653568565	DLGAP1	-0.0627112298591749
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/86	117/9376	0.93182269926456	CECR2	-0.0713966275811997
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/86	122/9376	0.893633244376668	PIK3CB	-0.113775325659695
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/86	253/9376	0.861843919477893	PIK3CB/UBC	-0.214332699460082
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	3/86	388/9376	0.842963318149125	PIK3CB/BACE2/BRAF	-0.303957208875799
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/86	133/9376	0.819723727924462	FOS	-0.201458186201303
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	2/86	268/9376	0.813606386671295	DUSP1/UBC	-0.297861190028878
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/86	138/9376	0.790023592854735	SPDYE2	-0.23908265577472
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/86	140/9376	0.778737541528239	SERPINE1	-0.25377965118481
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/86	144/9376	0.757105943152455	CXCL1	-0.282603309555923
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/86	144/9376	0.757105943152455	PIK3CB	-0.282603309555923
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/86	154/9376	0.707943219571127	FOS	-0.351594523360291
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/86	157/9376	0.694415642127092	ABCA1	-0.371506182469251
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/86	158/9376	0.690020606417427	GADD45G	-0.378068089545582
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/86	166/9376	0.656766601288877	GTF2I	-0.429280119764502
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/86	168/9376	0.648947951273533	RNF103-CHMP3	-0.441743842218219
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/86	173/9376	0.630192230138459	PIK3CB	-0.472347236747265
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/86	178/9376	0.612490201201986	LGR4	-0.50219570505788
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	3/86	480/9376	0.681395348837209	TNFRSF1B/UBC/BRAF	-0.689449323775918
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/86	187/9376	0.583012063176222	CXCL1	-0.554162553300762
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/86	194/9376	0.56197554543275	MYO7B	-0.593140508386011
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/86	195/9376	0.559093619558736	PIK3CB	-0.598612391205117
NA	NA	hsa04082	Neuroactive ligand signaling	1/86	199/9376	0.547855556854038	P2RY14	-0.620269429193649
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/86	205/9376	0.531820760068066	PIK3CB	-0.652090304281132
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/86	235/9376	0.463928748144483	SOS2	-0.800730924120389
NA	NA	hsa04519	Cadherin signaling	2/86	404/9376	0.539719088187888	KRT19/KRT23	-0.909904937483577
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/86	250/9376	0.436093023255814	MITF	-0.869489309632175
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/86	254/9376	0.429225416590368	FLT1	-0.887285648279551
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/86	368/9376	0.296258847320526	TNFRSF1B	-1.325103116586