ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005179 hormone activity 6/153 132/18639 0.0454545454545455 5.53743315508021 0.000776344365918318 0.207177101283603 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/153 29/18639 0.103448275862069 12.6024340770791 0.00169444041611762 0.207177101283603 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 11/153 484/18639 0.0227272727272727 2.76871657754011 0.00220653655892405 0.207177101283603 GO:0001216 DNA-binding transcription activator activity 11/153 491/18639 0.0224032586558045 2.72924403977477 0.00246527903591885 0.207177101283603 GO:0097110 scaffold protein binding 4/153 70/18639 0.0571428571428571 6.96134453781513 0.00262925164558249 0.207177101283603 GO:0048185 activin binding 2/153 11/18639 0.181818181818182 22.1497326203209 0.00350720072790783 0.207177101283603 GO:0004859 phospholipase inhibitor activity 2/153 12/18639 0.166666666666667 20.3039215686275 0.00418603952405487 0.207177101283603 GO:0071949 FAD binding 3/153 40/18639 0.075 9.13676470588235 0.00428965881225942 0.207177101283603 GO:0043560 insulin receptor substrate binding 2/153 13/18639 0.153846153846154 18.7420814479638 0.00492058764907063 0.207177101283603 GO:0042043 neurexin family protein binding 2/153 14/18639 0.142857142857143 17.4033613445378 0.00570989692967149 0.207177101283603 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/153 15/18639 0.133333333333333 16.243137254902 0.00655303082785418 0.207177101283603 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/153 15/18639 0.133333333333333 16.243137254902 0.00655303082785418 0.207177101283603 GO:0140776 protein-containing complex destabilizing activity 2/153 15/18639 0.133333333333333 16.243137254902 0.00655303082785418 0.207177101283603 GO:0140297 DNA-binding transcription factor binding 10/153 488/18639 0.0204918032786885 2.49638379942141 0.00710279241414364 0.207177101283603 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/153 16/18639 0.125 15.2279411764706 0.00744906431581493 0.207177101283603 GO:0055102 lipase inhibitor activity 2/153 16/18639 0.125 15.2279411764706 0.00744906431581493 0.207177101283603 GO:0034185 apolipoprotein binding 2/153 18/18639 0.111111111111111 13.5359477124183 0.00939618675909411 0.245959006340993 GO:0031625 ubiquitin protein ligase binding 7/153 302/18639 0.0231788079470199 2.82372419166342 0.0124699702595269 0.29723985423308 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/153 21/18639 0.0952380952380952 11.6022408963585 0.0126911398436596 0.29723985423308 GO:0015026 coreceptor activity 3/153 61/18639 0.0491803278688525 5.99132111861138 0.0137913216778581 0.306856907332342 GO:0044389 ubiquitin-like protein ligase binding 7/153 322/18639 0.0217391304347826 2.64833759590793 0.0171622720067973 0.340395738032989 GO:0051082 unfolded protein binding 4/153 121/18639 0.0330578512396694 4.02722411278561 0.0176900637688793 0.340395738032989 GO:0004709 MAP kinase kinase kinase activity 2/153 25/18639 0.08 9.74588235294118 0.0177467579378082 0.340395738032989 GO:0050750 low-density lipoprotein particle receptor binding 2/153 26/18639 0.0769230769230769 9.3710407239819 0.0191233560692691 0.340395738032989 GO:0052742 phosphatidylinositol kinase activity 2/153 26/18639 0.0769230769230769 9.3710407239819 0.0191233560692691 0.340395738032989 GO:0045296 cadherin binding 7/153 334/18639 0.0209580838323353 2.55318774216273 0.0205129962402411 0.351087820265665 GO:0044183 protein folding chaperone 3/153 75/18639 0.04 4.87294117647059 0.0238223040164708 0.388413979735505 GO:0001968 fibronectin binding 2/153 30/18639 0.0666666666666667 8.12156862745098 0.0250563303652372 0.388413979735505 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 7/153 349/18639 0.0200573065902579 2.44345187931906 0.0253123717131003 0.388413979735505 GO:0070325 lipoprotein particle receptor binding 2/153 31/18639 0.0645161290322581 7.8595825426945 0.0266423127504763 0.391039832472221 GO:0043425 bHLH transcription factor binding 2/153 32/18639 0.0625 7.61397058823529 0.0282678623051752 0.391039832472221 GO:0106310 protein serine kinase activity 7/153 361/18639 0.0193905817174515 2.36222910216718 0.0296685949315387 0.391039832472221 GO:0071889 14-3-3 protein binding 2/153 33/18639 0.0606060606060606 7.38324420677362 0.0299322317024169 0.391039832472221 GO:0001540 amyloid-beta binding 3/153 83/18639 0.036144578313253 4.40326009922041 0.0309258744848126 0.391039832472221 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/153 34/18639 0.0588235294117647 7.16608996539792 0.0316346830764044 0.391039832472221 GO:0051427 hormone receptor binding 2/153 34/18639 0.0588235294117647 7.16608996539792 0.0316346830764044 0.391039832472221 GO:0050660 flavin adenine dinucleotide binding 3/153 86/18639 0.0348837209302326 4.24965800273598 0.0338455044444708 0.407060796697014 GO:0140662 ATP-dependent protein folding chaperone 2/153 40/18639 0.05 6.09117647058824 0.0426089586368143 0.49104979976686 GO:0001727 lipid kinase activity 2/153 41/18639 0.0487804878048781 5.94261119081779 0.0445580969091046 0.49104979976686 GO:0004896 cytokine receptor activity 3/153 96/18639 0.03125 3.80698529411765 0.0445686276391039 0.49104979976686 GO:0008307 structural constituent of muscle 2/153 42/18639 0.0476190476190476 5.80112044817927 0.04653974265336 0.49104979976686 GO:0035198 miRNA binding 2/153 42/18639 0.0476190476190476 5.80112044817927 0.04653974265336 0.49104979976686 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/153 43/18639 0.0465116279069767 5.66621067031464 0.0485532386286334 0.49104979976686 GO:0008375 acetylglucosaminyltransferase activity 2/153 43/18639 0.0465116279069767 5.66621067031464 0.0485532386286334 0.49104979976686 GO:0005543 phospholipid binding 8/153 497/18639 0.0160965794768612 1.9609421233282 0.0527903076233436 0.491410271530403 GO:0004857 enzyme inhibitor activity 7/153 416/18639 0.0168269230769231 2.04991515837104 0.0560454238828425 0.491410271530403 GO:0004497 monooxygenase activity 3/153 106/18639 0.0283018867924528 3.44783573806881 0.0567738285902554 0.491410271530403 GO:0004222 metalloendopeptidase activity 3/153 110/18639 0.0272727272727273 3.32245989304813 0.0620553568754597 0.491410271530403 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/153 181/18639 0.0220994475138122 2.69223269418265 0.0621798213593558 0.491410271530403 GO:0008237 metallopeptidase activity 4/153 184/18639 0.0217391304347826 2.64833759590793 0.0652344329827697 0.491410271530403 GO:0001221 transcription coregulator binding 3/153 115/18639 0.0260869565217391 3.17800511508951 0.0689665946459574 0.491410271530403 GO:0005544 calcium-dependent phospholipid binding 2/153 53/18639 0.0377358490566038 4.59711431742508 0.0703013084026727 0.491410271530403 GO:0016860 intramolecular oxidoreductase activity 2/153 53/18639 0.0377358490566038 4.59711431742508 0.0703013084026727 0.491410271530403 GO:1990782 protein tyrosine kinase binding 3/153 117/18639 0.0256410256410256 3.1236802413273 0.0718250327198404 0.491410271530403 GO:0005031 tumor necrosis factor receptor activity 1/153 10/18639 0.1 12.1823529411765 0.0791376378967308 0.491410271530403 GO:0005131 growth hormone receptor binding 1/153 10/18639 0.1 12.1823529411765 0.0791376378967308 0.491410271530403 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/153 10/18639 0.1 12.1823529411765 0.0791376378967308 0.491410271530403 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/153 10/18639 0.1 12.1823529411765 0.0791376378967308 0.491410271530403 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/153 10/18639 0.1 12.1823529411765 0.0791376378967308 0.491410271530403 GO:0031434 mitogen-activated protein kinase kinase binding 1/153 10/18639 0.1 12.1823529411765 0.0791376378967308 0.491410271530403 GO:0061980 regulatory RNA binding 2/153 58/18639 0.0344827586206897 4.20081135902637 0.0821559298840842 0.491410271530403 GO:0046982 protein heterodimerization activity 6/153 369/18639 0.016260162601626 1.98087039693926 0.0840013747465815 0.491410271530403 GO:0001786 phosphatidylserine binding 2/153 59/18639 0.0338983050847458 4.1296111665005 0.0845962818402627 0.491410271530403 GO:0070888 E-box binding 2/153 59/18639 0.0338983050847458 4.1296111665005 0.0845962818402627 0.491410271530403 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/153 11/18639 0.0909090909090909 11.0748663101604 0.086700681613613 0.491410271530403 GO:0002162 dystroglycan binding 1/153 11/18639 0.0909090909090909 11.0748663101604 0.086700681613613 0.491410271530403 GO:0005114 type II transforming growth factor beta receptor binding 1/153 11/18639 0.0909090909090909 11.0748663101604 0.086700681613613 0.491410271530403 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/153 11/18639 0.0909090909090909 11.0748663101604 0.086700681613613 0.491410271530403 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/153 11/18639 0.0909090909090909 11.0748663101604 0.086700681613613 0.491410271530403 GO:0019206 nucleoside kinase activity 1/153 11/18639 0.0909090909090909 11.0748663101604 0.086700681613613 0.491410271530403 GO:0034713 type I transforming growth factor beta receptor binding 1/153 11/18639 0.0909090909090909 11.0748663101604 0.086700681613613 0.491410271530403 GO:0050998 nitric-oxide synthase binding 1/153 11/18639 0.0909090909090909 11.0748663101604 0.086700681613613 0.491410271530403 GO:0070697 activin receptor binding 1/153 11/18639 0.0909090909090909 11.0748663101604 0.086700681613613 0.491410271530403 GO:0003714 transcription corepressor activity 4/153 204/18639 0.0196078431372549 2.38869665513264 0.0875416462208642 0.491410271530403 GO:0003995 acyl-CoA dehydrogenase activity 1/153 12/18639 0.0833333333333333 10.1519607843137 0.0942020127126636 0.491410271530403 GO:0015132 prostaglandin transmembrane transporter activity 1/153 12/18639 0.0833333333333333 10.1519607843137 0.0942020127126636 0.491410271530403 GO:0016840 carbon-nitrogen lyase activity 1/153 12/18639 0.0833333333333333 10.1519607843137 0.0942020127126636 0.491410271530403 GO:0017166 vinculin binding 1/153 12/18639 0.0833333333333333 10.1519607843137 0.0942020127126636 0.491410271530403 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/153 12/18639 0.0833333333333333 10.1519607843137 0.0942020127126636 0.491410271530403 GO:0038024 cargo receptor activity 2/153 65/18639 0.0307692307692308 3.74841628959276 0.0996804023668713 0.491410271530403 GO:0019838 growth factor binding 3/153 136/18639 0.0220588235294118 2.68728373702422 0.101488850521799 0.491410271530403 GO:0005035 death receptor activity 1/153 13/18639 0.0769230769230769 9.3710407239819 0.101642131467963 0.491410271530403 GO:0008035 high-density lipoprotein particle binding 1/153 13/18639 0.0769230769230769 9.3710407239819 0.101642131467963 0.491410271530403 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/153 13/18639 0.0769230769230769 9.3710407239819 0.101642131467963 0.491410271530403 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/153 13/18639 0.0769230769230769 9.3710407239819 0.101642131467963 0.491410271530403 GO:0071714 icosanoid transmembrane transporter activity 1/153 13/18639 0.0769230769230769 9.3710407239819 0.101642131467963 0.491410271530403 GO:0071837 HMG box domain binding 1/153 13/18639 0.0769230769230769 9.3710407239819 0.101642131467963 0.491410271530403 GO:0016500 protein-hormone receptor activity 2/153 67/18639 0.0298507462686567 3.63652326602283 0.104864839514405 0.491410271530403 GO:1990841 promoter-specific chromatin binding 2/153 68/18639 0.0294117647058824 3.58304498269896 0.107484209954165 0.491410271530403 GO:0005545 1-phosphatidylinositol binding 1/153 14/18639 0.0714285714285714 8.70168067226891 0.109021534124755 0.491410271530403 GO:0008191 metalloendopeptidase inhibitor activity 1/153 14/18639 0.0714285714285714 8.70168067226891 0.109021534124755 0.491410271530403 GO:0031404 chloride ion binding 1/153 14/18639 0.0714285714285714 8.70168067226891 0.109021534124755 0.491410271530403 GO:0034236 protein kinase A catalytic subunit binding 1/153 14/18639 0.0714285714285714 8.70168067226891 0.109021534124755 0.491410271530403 GO:0043176 amine binding 1/153 14/18639 0.0714285714285714 8.70168067226891 0.109021534124755 0.491410271530403 GO:0044548 S100 protein binding 1/153 14/18639 0.0714285714285714 8.70168067226891 0.109021534124755 0.491410271530403 GO:0071933 Arp2/3 complex binding 1/153 14/18639 0.0714285714285714 8.70168067226891 0.109021534124755 0.491410271530403 GO:0019955 cytokine binding 3/153 144/18639 0.0208333333333333 2.53799019607843 0.115227676763429 0.491410271530403 GO:0004559 alpha-mannosidase activity 1/153 15/18639 0.0666666666666667 8.12156862745098 0.116340712931676 0.491410271530403 GO:0015929 hexosaminidase activity 1/153 15/18639 0.0666666666666667 8.12156862745098 0.116340712931676 0.491410271530403 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/153 15/18639 0.0666666666666667 8.12156862745098 0.116340712931676 0.491410271530403 GO:0031005 filamin binding 1/153 15/18639 0.0666666666666667 8.12156862745098 0.116340712931676 0.491410271530403 GO:0031386 protein tag activity 1/153 15/18639 0.0666666666666667 8.12156862745098 0.116340712931676 0.491410271530403 GO:0141047 molecular tag activity 1/153 15/18639 0.0666666666666667 8.12156862745098 0.116340712931676 0.491410271530403 GO:0004175 endopeptidase activity 6/153 405/18639 0.0148148148148148 1.80479302832244 0.116983685258811 0.491410271530403 GO:0048029 monosaccharide binding 2/153 74/18639 0.027027027027027 3.29252782193959 0.123551663057752 0.491410271530403 GO:0004708 MAP kinase kinase activity 1/153 16/18639 0.0625 7.61397058823529 0.123600156172734 0.491410271530403 GO:0015923 mannosidase activity 1/153 16/18639 0.0625 7.61397058823529 0.123600156172734 0.491410271530403 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/153 16/18639 0.0625 7.61397058823529 0.123600156172734 0.491410271530403 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/153 16/18639 0.0625 7.61397058823529 0.123600156172734 0.491410271530403 GO:0140328 floppase activity 1/153 16/18639 0.0625 7.61397058823529 0.123600156172734 0.491410271530403 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/153 17/18639 0.0588235294117647 7.16608996539792 0.130800348199022 0.491410271530403 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/153 17/18639 0.0588235294117647 7.16608996539792 0.130800348199022 0.491410271530403 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/153 17/18639 0.0588235294117647 7.16608996539792 0.130800348199022 0.491410271530403 GO:0019198 transmembrane receptor protein phosphatase activity 1/153 17/18639 0.0588235294117647 7.16608996539792 0.130800348199022 0.491410271530403 GO:0140375 immune receptor activity 3/153 156/18639 0.0192307692307692 2.34276018099548 0.137051371179739 0.491410271530403 GO:0046332 SMAD binding 2/153 79/18639 0.0253164556962025 3.08413998510797 0.137353066771311 0.491410271530403 GO:0008525 phosphatidylcholine transporter activity 1/153 18/18639 0.0555555555555556 6.76797385620915 0.137941769460195 0.491410271530403 GO:0035615 clathrin adaptor activity 1/153 18/18639 0.0555555555555556 6.76797385620915 0.137941769460195 0.491410271530403 GO:0098641 cadherin binding involved in cell-cell adhesion 1/153 18/18639 0.0555555555555556 6.76797385620915 0.137941769460195 0.491410271530403 GO:0048306 calcium-dependent protein binding 2/153 80/18639 0.025 3.04558823529412 0.140153263753247 0.491410271530403 GO:0001618 virus receptor activity 2/153 81/18639 0.0246913580246914 3.0079883805374 0.142965834871615 0.491410271530403 GO:0030971 receptor tyrosine kinase binding 2/153 81/18639 0.0246913580246914 3.0079883805374 0.142965834871615 0.491410271530403 GO:0003756 protein disulfide isomerase activity 1/153 19/18639 0.0526315789473684 6.41176470588235 0.145024896535679 0.491410271530403 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/153 19/18639 0.0526315789473684 6.41176470588235 0.145024896535679 0.491410271530403 GO:0046624 sphingolipid transporter activity 1/153 19/18639 0.0526315789473684 6.41176470588235 0.145024896535679 0.491410271530403 GO:0140272 exogenous protein binding 2/153 82/18639 0.024390243902439 2.9713055954089 0.145790392153272 0.491410271530403 GO:0033218 amide binding 4/153 247/18639 0.0161943319838057 1.97285067873303 0.145937975324498 0.491410271530403 GO:0004674 protein serine/threonine kinase activity 6/153 433/18639 0.0138568129330254 1.68808585789974 0.14651539198097 0.491410271530403 GO:0008083 growth factor activity 3/153 162/18639 0.0185185185185185 2.25599128540305 0.148456935059063 0.491410271530403 GO:0030165 PDZ domain binding 2/153 83/18639 0.0240963855421687 2.93550673281361 0.148626553083357 0.491410271530403 GO:0042277 peptide binding 4/153 249/18639 0.0160642570281124 1.9570044885424 0.148959981137335 0.491410271530403 GO:0051117 ATPase binding 2/153 84/18639 0.0238095238095238 2.90056022408964 0.151473940542816 0.491410271530403 GO:0001614 purinergic nucleotide receptor activity 1/153 20/18639 0.05 6.09117647058824 0.152050202165649 0.491410271530403 GO:0016502 nucleotide receptor activity 1/153 20/18639 0.05 6.09117647058824 0.152050202165649 0.491410271530403 GO:0031418 L-ascorbic acid binding 1/153 20/18639 0.05 6.09117647058824 0.152050202165649 0.491410271530403 GO:0042288 MHC class I protein binding 1/153 20/18639 0.05 6.09117647058824 0.152050202165649 0.491410271530403 GO:0043024 ribosomal small subunit binding 1/153 20/18639 0.05 6.09117647058824 0.152050202165649 0.491410271530403 GO:0003779 actin binding 6/153 443/18639 0.0135440180586907 1.64998008232638 0.157820870340812 0.491410271530403 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/153 21/18639 0.0476190476190476 5.80112044817927 0.159018155281748 0.491410271530403 GO:0008373 sialyltransferase activity 1/153 21/18639 0.0476190476190476 5.80112044817927 0.159018155281748 0.491410271530403 GO:0010314 phosphatidylinositol-5-phosphate binding 1/153 21/18639 0.0476190476190476 5.80112044817927 0.159018155281748 0.491410271530403 GO:0036122 BMP binding 1/153 21/18639 0.0476190476190476 5.80112044817927 0.159018155281748 0.491410271530403 GO:0051428 peptide hormone receptor binding 1/153 21/18639 0.0476190476190476 5.80112044817927 0.159018155281748 0.491410271530403 GO:0140312 cargo adaptor activity 1/153 21/18639 0.0476190476190476 5.80112044817927 0.159018155281748 0.491410271530403 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/153 89/18639 0.0224719101123595 2.73760740251157 0.165866446583451 0.49362720361042 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/153 89/18639 0.0224719101123595 2.73760740251157 0.165866446583451 0.49362720361042 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/153 22/18639 0.0454545454545455 5.53743315508021 0.16592922103757 0.49362720361042 GO:0140793 histone H2AXY142 phosphatase activity 2/153 90/18639 0.0222222222222222 2.70718954248366 0.168773568173987 0.49362720361042 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/153 91/18639 0.021978021978022 2.67744020685197 0.171689422429458 0.49362720361042 GO:0072341 modified amino acid binding 2/153 91/18639 0.021978021978022 2.67744020685197 0.171689422429458 0.49362720361042 GO:0004602 glutathione peroxidase activity 1/153 23/18639 0.0434782608695652 5.29667519181586 0.172783860838894 0.49362720361042 GO:0005212 structural constituent of eye lens 1/153 23/18639 0.0434782608695652 5.29667519181586 0.172783860838894 0.49362720361042 GO:0043274 phospholipase binding 1/153 23/18639 0.0434782608695652 5.29667519181586 0.172783860838894 0.49362720361042 GO:0070577 lysine-acetylated histone binding 1/153 23/18639 0.0434782608695652 5.29667519181586 0.172783860838894 0.49362720361042 GO:0140103 catalytic activity, acting on a glycoprotein 1/153 23/18639 0.0434782608695652 5.29667519181586 0.172783860838894 0.49362720361042 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 4/153 268/18639 0.0149253731343284 1.81826163301141 0.178817003537087 0.49362720361042 GO:0050431 transforming growth factor beta binding 1/153 24/18639 0.0416666666666667 5.07598039215686 0.179582532373684 0.49362720361042 GO:0050699 WW domain binding 1/153 24/18639 0.0416666666666667 5.07598039215686 0.179582532373684 0.49362720361042 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/153 24/18639 0.0416666666666667 5.07598039215686 0.179582532373684 0.49362720361042 GO:0140033 acetylation-dependent protein binding 1/153 24/18639 0.0416666666666667 5.07598039215686 0.179582532373684 0.49362720361042 GO:0005096 GTPase activator activity 4/153 271/18639 0.014760147601476 1.7981332754504 0.183707314859486 0.49362720361042 GO:0015662 P-type ion transporter activity 1/153 25/18639 0.04 4.87294117647059 0.186325689641846 0.49362720361042 GO:0120020 cholesterol transfer activity 1/153 25/18639 0.04 4.87294117647059 0.186325689641846 0.49362720361042 GO:0140358 P-type transmembrane transporter activity 1/153 25/18639 0.04 4.87294117647059 0.186325689641846 0.49362720361042 GO:0005126 cytokine receptor binding 4/153 275/18639 0.0145454545454545 1.77197860962567 0.190295951590387 0.49362720361042 GO:0008017 microtubule binding 4/153 276/18639 0.0144927536231884 1.76555839727195 0.1919549342098 0.49362720361042 GO:0004725 protein tyrosine phosphatase activity 2/153 98/18639 0.0204081632653061 2.48619447779112 0.192317287860859 0.49362720361042 GO:0042626 ATPase-coupled transmembrane transporter activity 2/153 98/18639 0.0204081632653061 2.48619447779112 0.192317287860859 0.49362720361042 GO:0005160 transforming growth factor beta receptor binding 1/153 26/18639 0.0384615384615385 4.68552036199095 0.193013782984748 0.49362720361042 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/153 26/18639 0.0384615384615385 4.68552036199095 0.193013782984748 0.49362720361042 GO:0008157 protein phosphatase 1 binding 1/153 26/18639 0.0384615384615385 4.68552036199095 0.193013782984748 0.49362720361042 GO:0034237 protein kinase A regulatory subunit binding 1/153 26/18639 0.0384615384615385 4.68552036199095 0.193013782984748 0.49362720361042 GO:0070006 metalloaminopeptidase activity 1/153 26/18639 0.0384615384615385 4.68552036199095 0.193013782984748 0.49362720361042 GO:0070412 R-SMAD binding 1/153 26/18639 0.0384615384615385 4.68552036199095 0.193013782984748 0.49362720361042 GO:0001217 DNA-binding transcription repressor activity 4/153 278/18639 0.0143884892086331 1.75285653829877 0.19528670969413 0.496329778245582 GO:0031406 carboxylic acid binding 3/153 187/18639 0.0160427807486631 1.95438817238125 0.198890180851603 0.496329778245582 GO:0008320 protein transmembrane transporter activity 1/153 27/18639 0.037037037037037 4.5119825708061 0.199647259114515 0.496329778245582 GO:0023026 MHC class II protein complex binding 1/153 27/18639 0.037037037037037 4.5119825708061 0.199647259114515 0.496329778245582 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/153 27/18639 0.037037037037037 4.5119825708061 0.199647259114515 0.496329778245582 GO:0043177 organic acid binding 3/153 189/18639 0.0158730158730159 1.93370681605976 0.203094296452793 0.502094232897182 GO:0051019 mitogen-activated protein kinase binding 1/153 28/18639 0.0357142857142857 4.35084033613445 0.206226561143071 0.504235273124541 GO:0097718 disordered domain specific binding 1/153 28/18639 0.0357142857142857 4.35084033613445 0.206226561143071 0.504235273124541 GO:0015631 tubulin binding 5/153 385/18639 0.012987012987013 1.58212375859435 0.21016402828925 0.511054604309924 GO:0043236 laminin binding 1/153 29/18639 0.0344827586206897 4.20081135902637 0.212752128610972 0.513555436527136 GO:0000149 SNARE binding 2/153 106/18639 0.0188679245283019 2.29855715871254 0.216257820995397 0.513555436527136 GO:0001965 G-protein alpha-subunit binding 1/153 30/18639 0.0333333333333333 4.06078431372549 0.219224397515997 0.513555436527136 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/153 30/18639 0.0333333333333333 4.06078431372549 0.219224397515997 0.513555436527136 GO:0031210 phosphatidylcholine binding 1/153 30/18639 0.0333333333333333 4.06078431372549 0.219224397515997 0.513555436527136 GO:0033612 receptor serine/threonine kinase binding 1/153 30/18639 0.0333333333333333 4.06078431372549 0.219224397515997 0.513555436527136 GO:0019888 protein phosphatase regulator activity 2/153 107/18639 0.0186915887850467 2.27707531610775 0.219270860539676 0.513555436527136 GO:0008327 methyl-CpG binding 1/153 31/18639 0.032258064516129 3.92979127134725 0.225643800341514 0.516223954538284 GO:0047499 calcium-independent phospholipase A2 activity 1/153 31/18639 0.032258064516129 3.92979127134725 0.225643800341514 0.516223954538284 GO:0070273 phosphatidylinositol-4-phosphate binding 1/153 31/18639 0.032258064516129 3.92979127134725 0.225643800341514 0.516223954538284 GO:0022884 macromolecule transmembrane transporter activity 1/153 32/18639 0.03125 3.80698529411765 0.232010766084622 0.516223954538284 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/153 32/18639 0.03125 3.80698529411765 0.232010766084622 0.516223954538284 GO:0047498 calcium-dependent phospholipase A2 activity 1/153 32/18639 0.03125 3.80698529411765 0.232010766084622 0.516223954538284 GO:0051059 NF-kappaB binding 1/153 32/18639 0.03125 3.80698529411765 0.232010766084622 0.516223954538284 GO:0071813 lipoprotein particle binding 1/153 32/18639 0.03125 3.80698529411765 0.232010766084622 0.516223954538284 GO:0071814 protein-lipid complex binding 1/153 32/18639 0.03125 3.80698529411765 0.232010766084622 0.516223954538284 GO:0120015 sterol transfer activity 1/153 32/18639 0.03125 3.80698529411765 0.232010766084622 0.516223954538284 GO:0005200 structural constituent of cytoskeleton 2/153 112/18639 0.0178571428571429 2.17542016806723 0.234385545483496 0.518913272339082 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/153 33/18639 0.0303030303030303 3.69162210338681 0.238325720284066 0.522438155302509 GO:0140416 transcription regulator inhibitor activity 1/153 33/18639 0.0303030303030303 3.69162210338681 0.238325720284066 0.522438155302509 GO:0017124 SH3 domain binding 2/153 115/18639 0.0173913043478261 2.11867007672634 0.243484912610893 0.523279532915052 GO:0035401 histone H3Y41 kinase activity 2/153 115/18639 0.0173913043478261 2.11867007672634 0.243484912610893 0.523279532915052 GO:0140801 histone H2AXY142 kinase activity 2/153 115/18639 0.0173913043478261 2.11867007672634 0.243484912610893 0.523279532915052 GO:0015020 glucuronosyltransferase activity 1/153 34/18639 0.0294117647058824 3.58304498269896 0.244589085047935 0.523279532915052 GO:0015035 protein-disulfide reductase activity 1/153 34/18639 0.0294117647058824 3.58304498269896 0.244589085047935 0.523279532915052 GO:0051015 actin filament binding 3/153 209/18639 0.0143540669856459 1.74866310160428 0.246144250527872 0.524087040597623 GO:0019208 phosphatase regulator activity 2/153 117/18639 0.0170940170940171 2.0824534942182 0.249559882124293 0.526446081090115 GO:0004623 phospholipase A2 activity 1/153 35/18639 0.0285714285714286 3.48067226890756 0.250801279081133 0.526446081090115 GO:0016229 steroid dehydrogenase activity 1/153 35/18639 0.0285714285714286 3.48067226890756 0.250801279081133 0.526446081090115 GO:0004033 aldo-keto reductase (NADPH) activity 1/153 36/18639 0.0277777777777778 3.38398692810458 0.256962717712642 0.534338361598718 GO:0004190 aspartic-type endopeptidase activity 1/153 36/18639 0.0277777777777778 3.38398692810458 0.256962717712642 0.534338361598718 GO:0023023 MHC protein complex binding 1/153 37/18639 0.027027027027027 3.29252782193959 0.263073812922553 0.541980771993222 GO:0070001 aspartic-type peptidase activity 1/153 37/18639 0.027027027027027 3.29252782193959 0.263073812922553 0.541980771993222 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/153 122/18639 0.0163934426229508 1.99710703953713 0.264764623277185 0.542950494738929 GO:0000146 microfilament motor activity 1/153 38/18639 0.0263157894736842 3.20588235294118 0.269134973368894 0.549381023619991 GO:0042826 histone deacetylase binding 2/153 127/18639 0.015748031496063 1.91848077813803 0.279972757321841 0.559324023738142 GO:0004177 aminopeptidase activity 1/153 40/18639 0.025 3.04558823529412 0.281109108152127 0.559324023738142 GO:0015036 disulfide oxidoreductase activity 1/153 40/18639 0.025 3.04558823529412 0.281109108152127 0.559324023738142 GO:0050997 quaternary ammonium group binding 1/153 40/18639 0.025 3.04558823529412 0.281109108152127 0.559324023738142 GO:0031490 chromatin DNA binding 2/153 128/18639 0.015625 1.90349264705882 0.283012563844683 0.559324023738142 GO:0035591 signaling adaptor activity 2/153 129/18639 0.0155038759689922 1.88873689010488 0.286051313952918 0.559324023738142 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/153 41/18639 0.024390243902439 2.9713055954089 0.287022883433203 0.559324023738142 GO:0042169 SH2 domain binding 1/153 41/18639 0.024390243902439 2.9713055954089 0.287022883433203 0.559324023738142 GO:0042287 MHC protein binding 1/153 41/18639 0.024390243902439 2.9713055954089 0.287022883433203 0.559324023738142 GO:0140318 protein transporter activity 1/153 41/18639 0.024390243902439 2.9713055954089 0.287022883433203 0.559324023738142 GO:0003924 GTPase activity 4/153 331/18639 0.0120845921450151 1.47218766660743 0.288822427575082 0.559324023738142 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/153 130/18639 0.0153846153846154 1.87420814479638 0.289088821257916 0.559324023738142 GO:0031072 heat shock protein binding 2/153 131/18639 0.0152671755725191 1.85990121239335 0.292124902461935 0.562751435478619 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/153 132/18639 0.0151515151515152 1.8458110516934 0.295159377320518 0.566146219429441 GO:0001046 core promoter sequence-specific DNA binding 1/153 44/18639 0.0227272727272727 2.76871657754011 0.304475778943373 0.56718008704177 GO:0001223 transcription coactivator binding 1/153 44/18639 0.0227272727272727 2.76871657754011 0.304475778943373 0.56718008704177 GO:0019205 nucleobase-containing compound kinase activity 1/153 44/18639 0.0227272727272727 2.76871657754011 0.304475778943373 0.56718008704177 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/153 44/18639 0.0227272727272727 2.76871657754011 0.304475778943373 0.56718008704177 GO:0002020 protease binding 2/153 136/18639 0.0147058823529412 1.79152249134948 0.307277713203991 0.56718008704177 GO:0140789 histone phosphatase activity 2/153 136/18639 0.0147058823529412 1.79152249134948 0.307277713203991 0.56718008704177 GO:0046915 transition metal ion transmembrane transporter activity 1/153 45/18639 0.0222222222222222 2.70718954248366 0.310198564951529 0.56718008704177 GO:0140303 intramembrane lipid transporter activity 1/153 45/18639 0.0222222222222222 2.70718954248366 0.310198564951529 0.56718008704177 GO:0030291 protein serine/threonine kinase inhibitor activity 1/153 46/18639 0.0217391304347826 2.64833759590793 0.315874569015335 0.56718008704177 GO:0004713 protein tyrosine kinase activity 2/153 140/18639 0.0142857142857143 1.74033613445378 0.319356696901928 0.56718008704177 GO:0005504 fatty acid binding 1/153 47/18639 0.0212765957446809 2.59198998748436 0.32150417106668 0.56718008704177 GO:0140359 ABC-type transporter activity 1/153 47/18639 0.0212765957446809 2.59198998748436 0.32150417106668 0.56718008704177 GO:0032266 phosphatidylinositol-3-phosphate binding 1/153 48/18639 0.0208333333333333 2.53799019607843 0.327087747972166 0.56718008704177 GO:0141003 histone H2AX kinase activity 4/153 354/18639 0.0112994350282486 1.37653705550017 0.331366691294425 0.56718008704177 GO:0001222 transcription corepressor binding 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0005004 GPI-linked ephrin receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0005008 hepatocyte growth factor receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0005009 insulin receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0005011 macrophage colony-stimulating factor receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0005020 stem cell factor receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0008288 boss receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0036332 placental growth factor receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0038062 protein tyrosine kinase collagen receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0060175 brain-derived neurotrophic factor receptor activity 1/153 49/18639 0.0204081632653061 2.48619447779112 0.332625673557679 0.56718008704177 GO:0008194 UDP-glycosyltransferase activity 2/153 145/18639 0.0137931034482759 1.68032454361055 0.334384693434046 0.56718008704177 GO:0140996 histone H3 kinase activity 4/153 357/18639 0.0112044817927171 1.36496951721865 0.33695194206121 0.56718008704177 GO:0005006 epidermal growth factor receptor activity 1/153 50/18639 0.02 2.43647058823529 0.338118318632755 0.56718008704177 GO:0005007 fibroblast growth factor receptor activity 1/153 50/18639 0.02 2.43647058823529 0.338118318632755 0.56718008704177 GO:0005017 platelet-derived growth factor receptor activity 1/153 50/18639 0.02 2.43647058823529 0.338118318632755 0.56718008704177 GO:0005019 platelet-derived growth factor beta-receptor activity 1/153 50/18639 0.02 2.43647058823529 0.338118318632755 0.56718008704177 GO:0035173 histone kinase activity 4/153 360/18639 0.0111111111111111 1.35359477124183 0.342541475009965 0.56718008704177 GO:0003743 translation initiation factor activity 1/153 51/18639 0.0196078431372549 2.38869665513264 0.343566051014766 0.56718008704177 GO:0005010 insulin-like growth factor receptor activity 1/153 51/18639 0.0196078431372549 2.38869665513264 0.343566051014766 0.56718008704177 GO:0005021 vascular endothelial growth factor receptor activity 1/153 51/18639 0.0196078431372549 2.38869665513264 0.343566051014766 0.56718008704177 GO:0005030 neurotrophin receptor activity 1/153 51/18639 0.0196078431372549 2.38869665513264 0.343566051014766 0.56718008704177 GO:0016597 amino acid binding 1/153 51/18639 0.0196078431372549 2.38869665513264 0.343566051014766 0.56718008704177 GO:0005080 protein kinase C binding 1/153 52/18639 0.0192307692307692 2.34276018099548 0.348969235552894 0.56718008704177 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/153 52/18639 0.0192307692307692 2.34276018099548 0.348969235552894 0.56718008704177 GO:0030159 signaling receptor complex adaptor activity 1/153 52/18639 0.0192307692307692 2.34276018099548 0.348969235552894 0.56718008704177 GO:0004864 protein phosphatase inhibitor activity 1/153 53/18639 0.0188679245283019 2.29855715871254 0.354328234151937 0.56718008704177 GO:0005003 ephrin receptor activity 1/153 53/18639 0.0188679245283019 2.29855715871254 0.354328234151937 0.56718008704177 GO:0005005 transmembrane-ephrin receptor activity 1/153 53/18639 0.0188679245283019 2.29855715871254 0.354328234151937 0.56718008704177 GO:0017046 peptide hormone binding 1/153 53/18639 0.0188679245283019 2.29855715871254 0.354328234151937 0.56718008704177 GO:0038064 collagen receptor activity 1/153 53/18639 0.0188679245283019 2.29855715871254 0.354328234151937 0.56718008704177 GO:0051018 protein kinase A binding 1/153 53/18639 0.0188679245283019 2.29855715871254 0.354328234151937 0.56718008704177 GO:0015485 cholesterol binding 1/153 54/18639 0.0185185185185185 2.25599128540305 0.359643405795904 0.567522395670841 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/153 54/18639 0.0185185185185185 2.25599128540305 0.359643405795904 0.567522395670841 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/153 54/18639 0.0185185185185185 2.25599128540305 0.359643405795904 0.567522395670841 GO:0140463 chromatin-protein adaptor activity 1/153 54/18639 0.0185185185185185 2.25599128540305 0.359643405795904 0.567522395670841 GO:0008374 O-acyltransferase activity 1/153 55/18639 0.0181818181818182 2.21497326203209 0.364915106571433 0.571785994451718 GO:0098632 cell-cell adhesion mediator activity 1/153 55/18639 0.0181818181818182 2.21497326203209 0.364915106571433 0.571785994451718 GO:0019212 phosphatase inhibitor activity 1/153 56/18639 0.0178571428571429 2.17542016806723 0.370143689691029 0.575139423973377 GO:0170055 lipid transmembrane transporter activity 1/153 56/18639 0.0178571428571429 2.17542016806723 0.370143689691029 0.575139423973377 GO:0030695 GTPase regulator activity 5/153 489/18639 0.0102249488752556 1.24563936003849 0.373912824909439 0.575139423973377 GO:0004601 peroxidase activity 1/153 57/18639 0.0175438596491228 2.13725490196078 0.375329505516099 0.575139423973377 GO:0060589 nucleoside-triphosphatase regulator activity 5/153 490/18639 0.0102040816326531 1.24309723889556 0.375544669471802 0.575139423973377 GO:0016757 glycosyltransferase activity 3/153 267/18639 0.0112359550561798 1.36880370125578 0.375623278128939 0.575139423973377 GO:0005525 GTP binding 4/153 378/18639 0.0105820105820106 1.28913787737317 0.376102409834276 0.575139423973377 GO:0004866 endopeptidase inhibitor activity 2/153 161/18639 0.0124223602484472 1.51333576909024 0.381751580302849 0.579663949531642 GO:0005178 integrin binding 2/153 161/18639 0.0124223602484472 1.51333576909024 0.381751580302849 0.579663949531642 GO:0003712 transcription coregulator activity 5/153 495/18639 0.0101010101010101 1.23054070112894 0.383703543017364 0.579663949531642 GO:0015459 potassium channel regulator activity 1/153 59/18639 0.0169491525423729 2.06480558325025 0.385574222609811 0.579663949531642 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/153 59/18639 0.0169491525423729 2.06480558325025 0.385574222609811 0.579663949531642 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/153 60/18639 0.0166666666666667 2.03039215686274 0.390633810550645 0.581378079247616 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/153 60/18639 0.0166666666666667 2.03039215686274 0.390633810550645 0.581378079247616 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/153 60/18639 0.0166666666666667 2.03039215686274 0.390633810550645 0.581378079247616 GO:0019905 syntaxin binding 1/153 61/18639 0.0163934426229508 1.99710703953713 0.395652004586156 0.585851863201514 GO:0015399 primary active transmembrane transporter activity 2/153 166/18639 0.0120481927710843 1.4677533664068 0.396272833311586 0.585851863201514 GO:0005201 extracellular matrix structural constituent 2/153 168/18639 0.0119047619047619 1.45028011204482 0.402038217512015 0.591726791909732 GO:0030246 carbohydrate binding 3/153 280/18639 0.0107142857142857 1.30525210084034 0.404446921306974 0.591726791909732 GO:0030414 peptidase inhibitor activity 2/153 169/18639 0.0118343195266272 1.44169857292029 0.404911297289127 0.591726791909732 GO:0005507 copper ion binding 1/153 63/18639 0.0158730158730159 1.93370681605976 0.405565554005546 0.591726791909732 GO:0035091 phosphatidylinositol binding 3/153 284/18639 0.0105633802816901 1.28686826843413 0.413243998536596 0.60041458987406 GO:0120013 lipid transfer activity 1/153 65/18639 0.0153846153846154 1.87420814479638 0.415317529960958 0.60041458987406 GO:0019001 guanyl nucleotide binding 4/153 400/18639 0.01 1.21823529411765 0.416917097238392 0.60041458987406 GO:0032561 guanyl ribonucleotide binding 4/153 400/18639 0.01 1.21823529411765 0.416917097238392 0.60041458987406 GO:0008235 metalloexopeptidase activity 1/153 66/18639 0.0151515151515152 1.8458110516934 0.420133747141747 0.60218214714569 GO:0004721 phosphoprotein phosphatase activity 2/153 175/18639 0.0114285714285714 1.39226890756303 0.422009746891898 0.60218214714569 GO:0004252 serine-type endopeptidase activity 2/153 176/18639 0.0113636363636364 1.38435828877005 0.424835384430865 0.60218214714569 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/153 67/18639 0.0149253731343284 1.81826163301141 0.424910548772464 0.60218214714569 GO:0050840 extracellular matrix binding 1/153 67/18639 0.0149253731343284 1.81826163301141 0.424910548772464 0.60218214714569 GO:0005548 phospholipid transporter activity 1/153 68/18639 0.0147058823529412 1.79152249134948 0.429648255321991 0.604280941711459 GO:0032934 sterol binding 1/153 68/18639 0.0147058823529412 1.79152249134948 0.429648255321991 0.604280941711459 GO:0005319 lipid transporter activity 2/153 178/18639 0.0112359550561798 1.36880370125578 0.430465300050635 0.604280941711459 GO:0008080 N-acetyltransferase activity 1/153 69/18639 0.0144927536231884 1.76555839727195 0.434347184670747 0.607812884209064 GO:0016853 isomerase activity 2/153 180/18639 0.0111111111111111 1.35359477124183 0.436066250071694 0.608305583955811 GO:0001664 G protein-coupled receptor binding 3/153 297/18639 0.0101010101010101 1.23054070112894 0.441541559572429 0.614018731280409 GO:0061135 endopeptidase regulator activity 2/153 184/18639 0.0108695652173913 1.32416879795396 0.447179037206806 0.617509071877588 GO:0016887 ATP hydrolysis activity 4/153 417/18639 0.00959232613908873 1.16857102553252 0.448065201985576 0.617509071877588 GO:0005518 collagen binding 1/153 72/18639 0.0138888888888889 1.69199346405229 0.448214449924631 0.617509071877588 GO:1901981 phosphatidylinositol phosphate binding 2/153 185/18639 0.0108108108108108 1.31701112877583 0.449938285806455 0.617970793777385 GO:0043539 protein serine/threonine kinase activator activity 1/153 73/18639 0.0136986301369863 1.66881547139404 0.452761398228694 0.619934837574673 GO:0035064 methylated histone binding 1/153 74/18639 0.0135135135135135 1.64626391096979 0.457271120628296 0.624189106379116 GO:0019003 GDP binding 1/153 75/18639 0.0133333333333333 1.6243137254902 0.461743919903484 0.626737591820451 GO:0019902 phosphatase binding 2/153 190/18639 0.0105263157894737 1.28235294117647 0.463617787840519 0.626737591820451 GO:0017022 myosin binding 1/153 76/18639 0.0131578947368421 1.60294117647059 0.466180096387796 0.626737591820451 GO:0098631 cell adhesion mediator activity 1/153 76/18639 0.0131578947368421 1.60294117647059 0.466180096387796 0.626737591820451 GO:0140034 methylation-dependent protein binding 1/153 76/18639 0.0131578947368421 1.60294117647059 0.466180096387796 0.626737591820451 GO:0008236 serine-type peptidase activity 2/153 194/18639 0.0103092783505155 1.25591267434809 0.474417947722632 0.631048782041765 GO:0019199 transmembrane receptor protein kinase activity 1/153 78/18639 0.0128205128205128 1.56184012066365 0.47494377020306 0.631048782041765 GO:0033293 monocarboxylic acid binding 1/153 79/18639 0.0126582278481013 1.54206999255398 0.479271856144492 0.631048782041765 GO:0016758 hexosyltransferase activity 2/153 197/18639 0.0101522842639594 1.23678710062705 0.482432238612979 0.631048782041765 GO:0017171 serine hydrolase activity 2/153 198/18639 0.0101010101010101 1.23054070112894 0.48508707039243 0.631048782041765 GO:0033192 calmodulin-dependent protein phosphatase activity 1/153 81/18639 0.0123456790123457 1.5039941902687 0.487821979825544 0.631048782041765 GO:0140791 histone H2AXS140 phosphatase activity 1/153 81/18639 0.0123456790123457 1.5039941902687 0.487821979825544 0.631048782041765 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/153 81/18639 0.0123456790123457 1.5039941902687 0.487821979825544 0.631048782041765 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/153 81/18639 0.0123456790123457 1.5039941902687 0.487821979825544 0.631048782041765 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/153 81/18639 0.0123456790123457 1.5039941902687 0.487821979825544 0.631048782041765 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/153 81/18639 0.0123456790123457 1.5039941902687 0.487821979825544 0.631048782041765 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/153 81/18639 0.0123456790123457 1.5039941902687 0.487821979825544 0.631048782041765 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/153 81/18639 0.0123456790123457 1.5039941902687 0.487821979825544 0.631048782041765 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/153 82/18639 0.0121951219512195 1.48565279770445 0.492044592019029 0.632831917481121 GO:0033549 MAP kinase phosphatase activity 1/153 82/18639 0.0121951219512195 1.48565279770445 0.492044592019029 0.632831917481121 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/153 83/18639 0.0120481927710843 1.4677533664068 0.496232616884098 0.63439293294841 GO:0008135 translation factor activity, RNA binding 1/153 83/18639 0.0120481927710843 1.4677533664068 0.496232616884098 0.63439293294841 GO:0004860 protein kinase inhibitor activity 1/153 84/18639 0.0119047619047619 1.45028011204482 0.500386335876162 0.63439293294841 GO:0017018 myosin phosphatase activity 1/153 84/18639 0.0119047619047619 1.45028011204482 0.500386335876162 0.63439293294841 GO:0180051 translation factor activity 1/153 84/18639 0.0119047619047619 1.45028011204482 0.500386335876162 0.63439293294841 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/153 86/18639 0.0116279069767442 1.41655266757866 0.508591970704653 0.641142852588019 GO:0016209 antioxidant activity 1/153 86/18639 0.0116279069767442 1.41655266757866 0.508591970704653 0.641142852588019 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/153 88/18639 0.0113636363636364 1.38435828877005 0.516663702969533 0.64947838367639 GO:0019210 kinase inhibitor activity 1/153 90/18639 0.0111111111111111 1.35359477124183 0.524603703599865 0.657601825639267 GO:0043178 alcohol binding 1/153 92/18639 0.0108695652173913 1.32416879795396 0.532414108557308 0.665517635696635 GO:0051213 dioxygenase activity 1/153 93/18639 0.010752688172043 1.30993042378242 0.536271370723196 0.666594301597269 GO:0051219 phosphoprotein binding 1/153 93/18639 0.010752688172043 1.30993042378242 0.536271370723196 0.666594301597269 GO:0016410 N-acyltransferase activity 1/153 94/18639 0.0106382978723404 1.29599499374218 0.540097019395651 0.667619926752958 GO:0042562 hormone binding 1/153 94/18639 0.0106382978723404 1.29599499374218 0.540097019395651 0.667619926752958 GO:0004867 serine-type endopeptidase inhibitor activity 1/153 95/18639 0.0105263157894737 1.28235294117647 0.543891311983004 0.670447739148025 GO:0016407 acetyltransferase activity 1/153 96/18639 0.0104166666666667 1.26899509803922 0.547654503811445 0.67322169667429 GO:0061134 peptidase regulator activity 2/153 226/18639 0.00884955752212389 1.07808433107756 0.555896928471391 0.67912535752023 GO:0043130 ubiquitin binding 1/153 100/18639 0.01 1.21823529411765 0.562401298118069 0.67912535752023 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/153 229/18639 0.00873362445414847 1.06396095556126 0.563066770776468 0.67912535752023 GO:0005085 guanyl-nucleotide exchange factor activity 2/153 230/18639 0.00869565217391304 1.05933503836317 0.565438391958446 0.67912535752023 GO:0008238 exopeptidase activity 1/153 102/18639 0.00980392156862745 1.19434832756632 0.569594578949804 0.67912535752023 GO:0004722 protein serine/threonine phosphatase activity 1/153 103/18639 0.00970873786407767 1.18275271273558 0.57314704317922 0.67912535752023 GO:0005125 cytokine activity 2/153 234/18639 0.00854700854700855 1.0412267471091 0.574832962902862 0.67912535752023 GO:0008013 beta-catenin binding 1/153 106/18639 0.00943396226415094 1.14927857935627 0.583630596483031 0.67912535752023 GO:0005496 steroid binding 1/153 108/18639 0.00925925925925926 1.12799564270152 0.590477115188636 0.67912535752023 GO:0004620 phospholipase activity 1/153 109/18639 0.00917431192660551 1.11764705882353 0.593858314334723 0.67912535752023 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/153 243/18639 0.00823045267489712 1.00266279351247 0.595431041887231 0.67912535752023 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0004711 ribosomal protein S6 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0035175 histone H3S10 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0035979 histone H2AXS139 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0044022 histone H3S28 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0044023 histone H4S1 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0044024 histone H2AS1 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0044025 histone H2BS14 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0072354 histone H3T3 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0072371 histone H2AS121 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0140823 histone H2BS36 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0140855 histone H3S57 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0140995 histone H2A kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0140997 histone H4 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:0140998 histone H2B kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:1990244 histone H2AT120 kinase activity 2/153 245/18639 0.00816326530612245 0.994477791116447 0.599906662390671 0.67912535752023 GO:1902936 phosphatidylinositol bisphosphate binding 1/153 111/18639 0.00900900900900901 1.09750927397986 0.600537731596356 0.67912535752023 GO:0004677 DNA-dependent protein kinase activity 2/153 246/18639 0.00813008130081301 0.990435198469632 0.602130589641928 0.67912535752023 GO:0140857 histone H3T45 kinase activity 2/153 246/18639 0.00813008130081301 0.990435198469632 0.602130589641928 0.67912535752023 GO:0043022 ribosome binding 1/153 112/18639 0.00892857142857143 1.08771008403361 0.603836399939715 0.67912535752023 GO:0035402 histone H3T11 kinase activity 2/153 247/18639 0.00809716599190283 0.986425339366516 0.604345261973059 0.67912535752023 GO:0035403 histone H3T6 kinase activity 2/153 247/18639 0.00809716599190283 0.986425339366516 0.604345261973059 0.67912535752023 GO:0004679 AMP-activated protein kinase activity 2/153 248/18639 0.00806451612903226 0.982447817836812 0.606550680461847 0.679886782885445 GO:0019887 protein kinase regulator activity 2/153 255/18639 0.00784313725490196 0.955478662053057 0.621729716832009 0.694900115072551 GO:0022853 active monoatomic ion transmembrane transporter activity 1/153 118/18639 0.00847457627118644 1.03240279162512 0.623067743626849 0.694900115072551 GO:0032182 ubiquitin-like protein binding 1/153 120/18639 0.00833333333333333 1.01519607843137 0.629269781731815 0.700062632176644 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/153 122/18639 0.00819672131147541 0.998553519768563 0.635370427654816 0.70508688355709 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/153 128/18639 0.0078125 0.951746323529412 0.653080348407467 0.722937201595331 GO:0016791 phosphatase activity 2/153 273/18639 0.00732600732600733 0.892480068950657 0.658693202923729 0.7238574705522 GO:0016298 lipase activity 1/153 130/18639 0.00769230769230769 0.93710407239819 0.658791630502564 0.7238574705522 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/153 130/18639 0.00769230769230769 0.93710407239819 0.658791630502564 0.7238574705522 GO:0051087 protein-folding chaperone binding 1/153 134/18639 0.00746268656716418 0.909130816505707 0.669935454544801 0.734288860276937 GO:0016779 nucleotidyltransferase activity 1/153 136/18639 0.00735294117647059 0.895761245674741 0.675371008325198 0.73661788898214 GO:0044325 transmembrane transporter binding 1/153 136/18639 0.00735294117647059 0.895761245674741 0.675371008325198 0.73661788898214 GO:0031267 small GTPase binding 2/153 283/18639 0.00706713780918728 0.860943670754521 0.677958608766669 0.73763222714222 GO:0030295 protein kinase activator activity 1/153 139/18639 0.00719424460431655 0.876428269149386 0.683358032858543 0.739888867693556 GO:0140767 enzyme-substrate adaptor activity 1/153 139/18639 0.00719424460431655 0.876428269149386 0.683358032858543 0.739888867693556 GO:0019207 kinase regulator activity 2/153 287/18639 0.00696864111498258 0.848944455831113 0.685415122928192 0.740314877920013 GO:0019903 protein phosphatase binding 1/153 144/18639 0.00694444444444444 0.845996732026144 0.696238184545184 0.750184000296869 GO:0015085 calcium ion transmembrane transporter activity 1/153 147/18639 0.00680272108843537 0.828731492597039 0.703715008599553 0.756408644509182 GO:0019209 kinase activator activity 1/153 148/18639 0.00675675675675676 0.823131955484897 0.706166425627688 0.757214600974268 GO:0019842 vitamin binding 1/153 150/18639 0.00666666666666667 0.812156862745098 0.711008970723234 0.760574499932306 GO:0003774 cytoskeletal motor activity 1/153 153/18639 0.0065359477124183 0.796232218377547 0.718124514494278 0.766343906354805 GO:0022804 active transmembrane transporter activity 3/153 457/18639 0.00656455142231947 0.799716823271978 0.727924429596874 0.774872445242647 GO:0140658 ATP-dependent chromatin remodeler activity 1/153 158/18639 0.00632911392405063 0.771034996276992 0.72959899900375 0.774872445242647 GO:0051020 GTPase binding 2/153 315/18639 0.00634920634920635 0.773482726423903 0.733737275540107 0.775904286594276 GO:0099106 ion channel regulator activity 1/153 160/18639 0.00625 0.761397058823529 0.734057763272337 0.775904286594276 GO:0016247 channel regulator activity 1/153 168/18639 0.00595238095238095 0.725140056022409 0.751174115953084 0.792114885305977 GO:0141108 transporter regulator activity 1/153 170/18639 0.00588235294117647 0.716608996539792 0.7552793305137 0.794560997821741 GO:0140030 modification-dependent protein binding 1/153 173/18639 0.00578034682080925 0.704182250935056 0.761311319619184 0.799017776487115 GO:0043021 ribonucleoprotein complex binding 1/153 177/18639 0.00564971751412429 0.688268527750083 0.769124791285923 0.805318899111143 GO:0140597 protein carrier chaperone 1/153 188/18639 0.00531914893617021 0.647997496871089 0.789325901738031 0.824530578106628 GO:0042578 phosphoric ester hydrolase activity 2/153 363/18639 0.00550964187327824 0.671204018797602 0.801965462623182 0.8357719692443 GO:0016829 lyase activity 1/153 200/18639 0.005 0.609117647058824 0.809364963662074 0.84151263745239 GO:0008094 ATP-dependent activity, acting on DNA 1/153 210/18639 0.00476190476190476 0.580112044817927 0.824608976883337 0.855363624039825 GO:0000287 magnesium ion binding 1/153 230/18639 0.00434782608695652 0.529667519181586 0.851557781016434 0.88126328500538 GO:0005539 glycosaminoglycan binding 1/153 242/18639 0.00413223140495868 0.503403014098201 0.865708187532241 0.893828639099414 GO:0042393 histone binding 1/153 247/18639 0.00404858299595142 0.493212669683258 0.871200899116357 0.897417592839766 GO:0140104 molecular carrier activity 1/153 249/18639 0.00401606425702811 0.489251122135601 0.873334960357215 0.897538238704297 GO:0003713 transcription coactivator activity 1/153 256/18639 0.00390625 0.475873161764706 0.880531259869678 0.90284887244702 GO:0003730 mRNA 3'-UTR binding 1/153 262/18639 0.00381679389312977 0.464975303098339 0.886375235055501 0.906751677240684 GO:0008514 organic anion transmembrane transporter activity 1/153 269/18639 0.00371747211895911 0.45287557402143 0.892835122935217 0.9112652057481 GO:0015291 secondary active transmembrane transporter activity 1/153 287/18639 0.00348432055749129 0.424472227915556 0.907819150187456 0.92443826506503 GO:0140097 catalytic activity, acting on DNA 1/153 336/18639 0.00297619047619048 0.362570028011204 0.938870840483392 0.953875625605273 GO:0061630 ubiquitin protein ligase activity 1/153 353/18639 0.0028328611898017 0.345109148475254 0.947003748863618 0.959946852492734 GO:0061659 ubiquitin-like protein ligase activity 1/153 372/18639 0.00268817204301075 0.327482605945604 0.954827010267617 0.965677317202476 GO:0140098 catalytic activity, acting on RNA 1/153 387/18639 0.00258397932816537 0.314789481684146 0.960183346322561 0.968892492320952 GO:0004842 ubiquitin-protein transferase activity 1/153 449/18639 0.0022271714922049 0.271321891785667 0.976394186751552 0.981001736891229 GO:0046873 metal ion transmembrane transporter activity 1/153 450/18639 0.00222222222222222 0.270718954248366 0.976592740320931 0.981001736891229 GO:0019787 ubiquitin-like protein transferase activity 1/153 479/18639 0.00208768267223382 0.254328871423308 0.98168196184404 0.983892957253599 GO:0016755 aminoacyltransferase activity 1/153 496/18639 0.00201612903225806 0.245611954459203 0.984137006212033 0.984137006212033