ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0005179	hormone activity	8/245	132/18639	0.0606060606060606	4.61076066790353	0.000360810193614051	0.224063130234326
GO:0034185	apolipoprotein binding	3/245	18/18639	0.166666666666667	12.6795918367347	0.00158188912289645	0.338524733655284
GO:0030695	GTPase regulator activity	15/245	489/18639	0.0306748466257669	2.33366720921497	0.00213832813814042	0.338524733655284
GO:0060589	nucleoside-triphosphatase regulator activity	15/245	490/18639	0.0306122448979592	2.32890462307372	0.00218051358232067	0.338524733655284
GO:0044389	ubiquitin-like protein ligase binding	11/245	322/18639	0.0341614906832298	2.59892255038661	0.00368548599696573	0.457737360823144
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/245	29/18639	0.103448275862069	7.87009148486981	0.00636927562925965	0.527578366684661
GO:0031625	ubiquitin protein ligase binding	10/245	302/18639	0.033112582781457	2.51912420597378	0.00682881039653383	0.527578366684661
GO:0048185	activin binding	2/245	11/18639	0.181818181818182	13.8322820037106	0.00875221749227157	0.527578366684661
GO:0070990	snRNP binding	2/245	11/18639	0.181818181818182	13.8322820037106	0.00875221749227157	0.527578366684661
GO:0015166	polyol transmembrane transporter activity	2/245	12/18639	0.166666666666667	12.6795918367347	0.0104122423507015	0.527578366684661
GO:0019855	calcium channel inhibitor activity	2/245	13/18639	0.153846153846154	11.7042386185243	0.0121995538485199	0.527578366684661
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/245	13/18639	0.153846153846154	11.7042386185243	0.0121995538485199	0.527578366684661
GO:0140297	DNA-binding transcription factor binding	13/245	488/18639	0.0266393442622951	2.02665607226497	0.0127823631033037	0.527578366684661
GO:0004497	monooxygenase activity	5/245	106/18639	0.0471698113207547	3.58856372737774	0.0130453682419097	0.527578366684661
GO:0005545	1-phosphatidylinositol binding	2/245	14/18639	0.142857142857143	10.868221574344	0.014110547058894	0.527578366684661
GO:0044548	S100 protein binding	2/245	14/18639	0.142857142857143	10.868221574344	0.014110547058894	0.527578366684661
GO:0003779	actin binding	12/245	443/18639	0.0270880361173815	2.06079144976275	0.0145852051344331	0.527578366684661
GO:0071949	FAD binding	3/245	40/18639	0.075	5.70581632653061	0.015497121524134	0.527578366684661
GO:0015250	water channel activity	2/245	15/18639	0.133333333333333	10.1436734693878	0.0161416891578238	0.527578366684661
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	10/245	349/18639	0.0286532951289398	2.17987252207473	0.0174645219439712	0.539580924999732
GO:0008375	acetylglucosaminyltransferase activity	3/245	43/18639	0.0697674418604651	5.30773611770289	0.0188107329974774	0.539580924999732
GO:0030291	protein serine/threonine kinase inhibitor activity	3/245	46/18639	0.0652173913043478	4.96157941437445	0.0224861094093237	0.539580924999732
GO:0005372	water transmembrane transporter activity	2/245	18/18639	0.111111111111111	8.4530612244898	0.0229217357724877	0.539580924999732
GO:0035615	clathrin adaptor activity	2/245	18/18639	0.111111111111111	8.4530612244898	0.0229217357724877	0.539580924999732
GO:0004860	protein kinase inhibitor activity	4/245	84/18639	0.0476190476190476	3.62274052478134	0.0248060392776925	0.539580924999732
GO:0050660	flavin adenine dinucleotide binding	4/245	86/18639	0.0465116279069767	3.53849074513526	0.0267584274071394	0.539580924999732
GO:0140030	modification-dependent protein binding	6/245	173/18639	0.0346820809248555	2.63852778105462	0.0270140527282133	0.539580924999732
GO:0005096	GTPase activator activity	8/245	271/18639	0.029520295202952	2.24583176444009	0.0272765275761244	0.539580924999732
GO:0001614	purinergic nucleotide receptor activity	2/245	20/18639	0.1	7.60775510204082	0.0279808742928592	0.539580924999732
GO:0016502	nucleotide receptor activity	2/245	20/18639	0.1	7.60775510204082	0.0279808742928592	0.539580924999732
GO:0036122	BMP binding	2/245	21/18639	0.0952380952380952	7.24548104956268	0.0306626019753628	0.539580924999732
GO:0051428	peptide hormone receptor binding	2/245	21/18639	0.0952380952380952	7.24548104956268	0.0306626019753628	0.539580924999732
GO:0140312	cargo adaptor activity	2/245	21/18639	0.0952380952380952	7.24548104956268	0.0306626019753628	0.539580924999732
GO:0019210	kinase inhibitor activity	4/245	90/18639	0.0444444444444444	3.38122448979592	0.0309325622412316	0.539580924999732
GO:0005246	calcium channel regulator activity	3/245	53/18639	0.0566037735849057	4.30627647285329	0.0324697700493543	0.539580924999732
GO:0005544	calcium-dependent phospholipid binding	3/245	53/18639	0.0566037735849057	4.30627647285329	0.0324697700493543	0.539580924999732
GO:0005085	guanyl-nucleotide exchange factor activity	7/245	230/18639	0.0304347826086957	2.31540372670807	0.0327460144576699	0.539580924999732
GO:0019838	growth factor binding	5/245	136/18639	0.0367647058823529	2.79696878751501	0.0339124675941206	0.539580924999732
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3/245	54/18639	0.0555555555555556	4.2265306122449	0.0340558291048593	0.539580924999732
GO:0008237	metallopeptidase activity	6/245	184/18639	0.0326086956521739	2.48078970718722	0.0349831620074145	0.539580924999732
GO:0070577	lysine-acetylated histone binding	2/245	23/18639	0.0869565217391304	6.61543921916593	0.036315061765583	0.539580924999732
GO:0004867	serine-type endopeptidase inhibitor activity	4/245	95/18639	0.0421052631578947	3.20326530612245	0.0366604678644391	0.539580924999732
GO:0004896	cytokine receptor activity	4/245	96/18639	0.0416666666666667	3.16989795918367	0.0378745047841975	0.539580924999732
GO:0001091	RNA polymerase II general transcription initiation factor binding	2/245	24/18639	0.0833333333333333	6.33979591836735	0.0392798559854111	0.539580924999732
GO:0140033	acetylation-dependent protein binding	2/245	24/18639	0.0833333333333333	6.33979591836735	0.0392798559854111	0.539580924999732
GO:0015662	P-type ion transporter activity	2/245	25/18639	0.08	6.08620408163265	0.0423331691988325	0.539580924999732
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/245	25/18639	0.08	6.08620408163265	0.0423331691988325	0.539580924999732
GO:0140358	P-type transmembrane transporter activity	2/245	25/18639	0.08	6.08620408163265	0.0423331691988325	0.539580924999732
GO:0031593	polyubiquitin modification-dependent protein binding	3/245	59/18639	0.0508474576271186	3.86835005188516	0.0425756285426519	0.539580924999732
GO:0050750	low-density lipoprotein particle receptor binding	2/245	26/18639	0.0769230769230769	5.85211930926217	0.0454721829028863	0.552387066993601
GO:0052742	phosphatidylinositol kinase activity	2/245	26/18639	0.0769230769230769	5.85211930926217	0.0454721829028863	0.552387066993601
GO:0015026	coreceptor activity	3/245	61/18639	0.0491803278688525	3.74151890264302	0.0462546336290938	0.552387066993601
GO:0008395	steroid hydroxylase activity	2/245	27/18639	0.0740740740740741	5.63537414965986	0.0486941368605076	0.563018709853579
GO:0004857	enzyme inhibitor activity	10/245	416/18639	0.0240384615384615	1.82878728414443	0.0489581486829199	0.563018709853579
GO:0046966	nuclear thyroid hormone receptor binding	2/245	28/18639	0.0714285714285714	5.43411078717201	0.0519963280661065	0.567121540787233
GO:0051019	mitogen-activated protein kinase binding	2/245	28/18639	0.0714285714285714	5.43411078717201	0.0519963280661065	0.567121540787233
GO:0038024	cargo receptor activity	3/245	65/18639	0.0461538461538462	3.5112715855573	0.0540659637973792	0.567121540787233
GO:0043236	laminin binding	2/245	29/18639	0.0689655172413793	5.24672765657987	0.0553761097280951	0.567121540787233
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	11/245	484/18639	0.0227272727272727	1.72903525046382	0.0557384590536773	0.567121540787233
GO:0004222	metalloendopeptidase activity	4/245	110/18639	0.0363636363636364	2.76645640074211	0.0572695487504529	0.567121540787233
GO:0051015	actin filament binding	6/245	209/18639	0.0287081339712919	2.18404452690167	0.0582993061035875	0.567121540787233
GO:0001968	fibronectin binding	2/245	30/18639	0.0666666666666667	5.07183673469388	0.0588308902681017	0.567121540787233
GO:0001216	DNA-binding transcription activator activity	11/245	491/18639	0.0224032586558045	1.70438505341037	0.0604784221244613	0.567121540787233
GO:0004866	endopeptidase inhibitor activity	5/245	161/18639	0.031055900621118	2.36265686398783	0.0616755130423559	0.567121540787233
GO:0070325	lipoprotein particle receptor binding	2/245	31/18639	0.0645161290322581	4.90822909809085	0.0623581323366092	0.567121540787233
GO:0097110	scaffold protein binding	3/245	70/18639	0.0428571428571429	3.26046647230321	0.0646545559044848	0.567121540787233
GO:0017124	SH3 domain binding	4/245	115/18639	0.0347826086956522	2.64617568766637	0.0652707071994421	0.567121540787233
GO:0051059	NF-kappaB binding	2/245	32/18639	0.0625	4.75484693877551	0.065955351844764	0.567121540787233
GO:0071813	lipoprotein particle binding	2/245	32/18639	0.0625	4.75484693877551	0.065955351844764	0.567121540787233
GO:0071814	protein-lipid complex binding	2/245	32/18639	0.0625	4.75484693877551	0.065955351844764	0.567121540787233
GO:0022853	active monoatomic ion transmembrane transporter activity	4/245	118/18639	0.0338983050847458	2.57890003459011	0.0703370632008014	0.567121540787233
GO:0030414	peptidase inhibitor activity	5/245	169/18639	0.029585798816568	2.25081511894699	0.0726444584980111	0.567121540787233
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/245	34/18639	0.0588235294117647	4.47515006002401	0.0733500474299407	0.567121540787233
GO:0051427	hormone receptor binding	2/245	34/18639	0.0588235294117647	4.47515006002401	0.0733500474299407	0.567121540787233
GO:0045296	cadherin binding	8/245	334/18639	0.0239520958083832	1.82221679090798	0.0746690227096883	0.567121540787233
GO:0042826	histone deacetylase binding	4/245	127/18639	0.031496062992126	2.39614333922545	0.0866999274192526	0.567121540787233
GO:0048306	calcium-dependent protein binding	3/245	80/18639	0.0375	2.85290816326531	0.0884078866712509	0.567121540787233
GO:0005125	cytokine activity	6/245	234/18639	0.0256410256410256	1.95070643642072	0.0891122835956573	0.567121540787233
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	5/245	181/18639	0.0276243093922652	2.1015898071936	0.0909602247381292	0.567121540787233
GO:0001618	virus receptor activity	3/245	81/18639	0.037037037037037	2.81768707482993	0.090960350054871	0.567121540787233
GO:0016298	lipase activity	4/245	130/18639	0.0307692307692308	2.34084772370487	0.092530902273875	0.567121540787233
GO:0140272	exogenous protein binding	3/245	82/18639	0.0365853658536585	2.78332503733201	0.0935433054871627	0.567121540787233
GO:0061135	endopeptidase regulator activity	5/245	184/18639	0.0271739130434783	2.06732475598935	0.0958800426072044	0.567121540787233
GO:0030165	PDZ domain binding	3/245	83/18639	0.036144578313253	2.74979100073764	0.0961563086375093	0.567121540787233
GO:0015036	disulfide oxidoreductase activity	2/245	40/18639	0.05	3.80387755102041	0.0969710411782782	0.567121540787233
GO:0015144	carbohydrate transmembrane transporter activity	2/245	40/18639	0.05	3.80387755102041	0.0969710411782782	0.567121540787233
GO:0001727	lipid kinase activity	2/245	41/18639	0.0487804878048781	3.71110004977601	0.101094602464787	0.567121540787233
GO:0017080	sodium channel regulator activity	2/245	41/18639	0.0487804878048781	3.71110004977601	0.101094602464787	0.567121540787233
GO:0004712	protein serine/threonine/tyrosine kinase activity	2/245	43/18639	0.0465116279069767	3.53849074513526	0.109483359153116	0.567121540787233
GO:0008200	ion channel inhibitor activity	2/245	43/18639	0.0465116279069767	3.53849074513526	0.109483359153116	0.567121540787233
GO:0001046	core promoter sequence-specific DNA binding	2/245	44/18639	0.0454545454545455	3.45807050092764	0.113744681884668	0.567121540787233
GO:0016248	channel inhibitor activity	2/245	44/18639	0.0454545454545455	3.45807050092764	0.113744681884668	0.567121540787233
GO:0141110	transporter inhibitor activity	2/245	45/18639	0.0444444444444444	3.38122448979592	0.118048123007068	0.567121540787233
GO:0019887	protein kinase regulator activity	6/245	255/18639	0.0235294117647059	1.7900600240096	0.120677182695996	0.567121540787233
GO:0005543	phospholipid binding	10/245	497/18639	0.0201207243460765	1.5307354330062	0.121111699151129	0.567121540787233
GO:0019955	cytokine binding	4/245	144/18639	0.0277777777777778	2.11326530612245	0.122076239435913	0.567121540787233
GO:0001094	TFIID-class transcription factor complex binding	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0005337	nucleoside transmembrane transporter activity	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0005345	purine nucleobase transmembrane transporter activity	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0005522	profilin binding	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0016427	tRNA (cytidine) methyltransferase activity	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0019531	oxalate transmembrane transporter activity	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0030957	Tat protein binding	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0042975	peroxisome proliferator activated receptor binding	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0045322	unmethylated CpG binding	1/245	10/18639	0.1	7.60775510204082	0.123964374954387	0.567121540787233
GO:0016410	N-acyltransferase activity	3/245	94/18639	0.0319148936170213	2.42800694745983	0.126752040673492	0.567121540787233
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0005114	type II transforming growth factor beta receptor binding	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0008046	axon guidance receptor activity	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0008271	secondary active sulfate transmembrane transporter activity	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0010854	adenylate cyclase regulator activity	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0015205	nucleobase transmembrane transporter activity	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0032794	GTPase activating protein binding	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0034056	estrogen response element binding	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0034713	type I transforming growth factor beta receptor binding	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0042608	T cell receptor binding	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0070697	activin receptor binding	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/245	11/18639	0.0909090909090909	6.91614100185529	0.135485590700599	0.567121540787233
GO:0019842	vitamin binding	4/245	150/18639	0.0266666666666667	2.02873469387755	0.135834588058198	0.567121540787233
GO:0042626	ATPase-coupled transmembrane transporter activity	3/245	98/18639	0.0306122448979592	2.32890462307372	0.138645308806273	0.567121540787233
GO:0043130	ubiquitin binding	3/245	100/18639	0.03	2.28232653061224	0.144729387422153	0.567121540787233
GO:0003995	acyl-CoA dehydrogenase activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0004126	cytidine deaminase activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0004859	phospholipase inhibitor activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0008603	cAMP-dependent protein kinase regulator activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0010853	cyclase activator activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0015132	prostaglandin transmembrane transporter activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0016840	carbon-nitrogen lyase activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0035259	nuclear glucocorticoid receptor binding	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0036009	protein-glutamine N-methyltransferase activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0070679	inositol 1,4,5 trisphosphate binding	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0097371	MDM2/MDM4 family protein binding	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0140900	chloride:bicarbonate antiporter activity	1/245	12/18639	0.0833333333333333	6.33979591836735	0.146855895096044	0.567121540787233
GO:0005080	protein kinase C binding	2/245	52/18639	0.0384615384615385	2.92605965463108	0.149202682067867	0.567121540787233
GO:0140375	immune receptor activity	4/245	156/18639	0.0256410256410256	1.95070643642072	0.150190391876364	0.567121540787233
GO:0016860	intramolecular oxidoreductase activity	2/245	53/18639	0.0377358490566038	2.8708509819022	0.153780443323495	0.567121540787233
GO:0140296	general transcription initiation factor binding	2/245	53/18639	0.0377358490566038	2.8708509819022	0.153780443323495	0.567121540787233
GO:0004465	lipoprotein lipase activity	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0008035	high-density lipoprotein particle binding	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0031432	titin binding	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0043560	insulin receptor substrate binding	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0045159	myosin II binding	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0071714	icosanoid transmembrane transporter activity	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0071837	HMG box domain binding	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/245	13/18639	0.0769230769230769	5.85211930926217	0.158077256866671	0.567121540787233
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	2/245	54/18639	0.037037037037037	2.81768707482993	0.158385236178058	0.567121540787233
GO:0140463	chromatin-protein adaptor activity	2/245	54/18639	0.037037037037037	2.81768707482993	0.158385236178058	0.567121540787233
GO:0099106	ion channel regulator activity	4/245	160/18639	0.025	1.9019387755102	0.160070796613439	0.567121540787233
GO:0140313	molecular sequestering activity	2/245	55/18639	0.0363636363636364	2.76645640074211	0.163015567972388	0.567121540787233
GO:0008083	growth factor activity	4/245	162/18639	0.0246913580246914	1.87845804988662	0.165098851160511	0.567121540787233
GO:0004175	endopeptidase activity	8/245	405/18639	0.0197530864197531	1.5027664399093	0.165774409810844	0.567121540787233
GO:0170055	lipid transmembrane transporter activity	2/245	56/18639	0.0357142857142857	2.71705539358601	0.167669980319517	0.567121540787233
GO:0004065	arylsulfatase activity	1/245	14/18639	0.0714285714285714	5.43411078717201	0.169151619159577	0.567121540787233
GO:0008174	mRNA methyltransferase activity	1/245	14/18639	0.0714285714285714	5.43411078717201	0.169151619159577	0.567121540787233
GO:0008191	metalloendopeptidase inhibitor activity	1/245	14/18639	0.0714285714285714	5.43411078717201	0.169151619159577	0.567121540787233
GO:0032036	myosin heavy chain binding	1/245	14/18639	0.0714285714285714	5.43411078717201	0.169151619159577	0.567121540787233
GO:0034236	protein kinase A catalytic subunit binding	1/245	14/18639	0.0714285714285714	5.43411078717201	0.169151619159577	0.567121540787233
GO:0043176	amine binding	1/245	14/18639	0.0714285714285714	5.43411078717201	0.169151619159577	0.567121540787233
GO:0061665	SUMO ligase activity	1/245	14/18639	0.0714285714285714	5.43411078717201	0.169151619159577	0.567121540787233
GO:0071933	Arp2/3 complex binding	1/245	14/18639	0.0714285714285714	5.43411078717201	0.169151619159577	0.567121540787233
GO:1901474	azole transmembrane transporter activity	1/245	14/18639	0.0714285714285714	5.43411078717201	0.169151619159577	0.567121540787233
GO:0004620	phospholipase activity	3/245	109/18639	0.0275229357798165	2.09387755102041	0.173124346683353	0.567121540787233
GO:0015399	primary active transmembrane transporter activity	4/245	166/18639	0.0240963855421687	1.83319400049176	0.17532198187288	0.567121540787233
GO:0061134	peptidase regulator activity	5/245	226/18639	0.0221238938053097	1.68313165974354	0.177625841043158	0.567121540787233
GO:0019207	kinase regulator activity	6/245	287/18639	0.0209059233449477	1.590471449904	0.17778032333427	0.567121540787233
GO:0004559	alpha-mannosidase activity	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0005523	tropomyosin binding	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0015116	sulfate transmembrane transporter activity	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0015929	hexosaminidase activity	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0017081	chloride channel regulator activity	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0031005	filamin binding	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0031386	protein tag activity	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0042809	nuclear vitamin D receptor binding	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0140776	protein-containing complex destabilizing activity	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0141047	molecular tag activity	1/245	15/18639	0.0666666666666667	5.07183673469388	0.180080899873988	0.567121540787233
GO:0005201	extracellular matrix structural constituent	4/245	168/18639	0.0238095238095238	1.81137026239067	0.180513545801167	0.567121540787233
GO:0016247	channel regulator activity	4/245	168/18639	0.0238095238095238	1.81137026239067	0.180513545801167	0.567121540787233
GO:0001786	phosphatidylserine binding	2/245	59/18639	0.0338983050847458	2.57890003459011	0.18176361759178	0.567121540787233
GO:0141108	transporter regulator activity	4/245	170/18639	0.0235294117647059	1.7900600240096	0.185756083578815	0.567121540787233
GO:0001098	basal transcription machinery binding	2/245	60/18639	0.0333333333333333	2.53591836734694	0.186500431658061	0.567121540787233
GO:0001099	basal RNA polymerase II transcription machinery binding	2/245	60/18639	0.0333333333333333	2.53591836734694	0.186500431658061	0.567121540787233
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0005159	insulin-like growth factor receptor binding	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0005521	lamin binding	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0008296	3'-5'-DNA exonuclease activity	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0015562	efflux transmembrane transporter activity	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0015923	mannosidase activity	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0019841	retinol binding	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0055102	lipase inhibitor activity	1/245	16/18639	0.0625	4.75484693877551	0.190866991987974	0.567121540787233
GO:0008484	sulfuric ester hydrolase activity	1/245	17/18639	0.0588235294117647	4.47515006002401	0.201511763880952	0.582791821568011
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/245	17/18639	0.0588235294117647	4.47515006002401	0.201511763880952	0.582791821568011
GO:0030169	low-density lipoprotein particle binding	1/245	17/18639	0.0588235294117647	4.47515006002401	0.201511763880952	0.582791821568011
GO:0046965	nuclear retinoid X receptor binding	1/245	17/18639	0.0588235294117647	4.47515006002401	0.201511763880952	0.582791821568011
GO:0048038	quinone binding	1/245	17/18639	0.0588235294117647	4.47515006002401	0.201511763880952	0.582791821568011
GO:0004252	serine-type endopeptidase activity	4/245	176/18639	0.0227272727272727	1.72903525046382	0.201771725663643	0.582791821568011
GO:0003712	transcription coregulator activity	9/245	495/18639	0.0181818181818182	1.38322820037106	0.205581502355226	0.591046819271274
GO:0032182	ubiquitin-like protein binding	3/245	120/18639	0.025	1.9019387755102	0.209711722871754	0.5922361758085
GO:0000400	four-way junction DNA binding	1/245	18/18639	0.0555555555555556	4.2265306122449	0.212017059652039	0.5922361758085
GO:0003746	translation elongation factor activity	1/245	18/18639	0.0555555555555556	4.2265306122449	0.212017059652039	0.5922361758085
GO:0016854	racemase and epimerase activity	1/245	18/18639	0.0555555555555556	4.2265306122449	0.212017059652039	0.5922361758085
GO:0030228	lipoprotein particle receptor activity	1/245	18/18639	0.0555555555555556	4.2265306122449	0.212017059652039	0.5922361758085
GO:0050811	GABA receptor binding	1/245	18/18639	0.0555555555555556	4.2265306122449	0.212017059652039	0.5922361758085
GO:0016853	isomerase activity	4/245	180/18639	0.0222222222222222	1.69061224489796	0.212670961683246	0.5922361758085
GO:0008235	metalloexopeptidase activity	2/245	66/18639	0.0303030303030303	2.30538033395176	0.21524095027807	0.595262492882295
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/245	67/18639	0.0298507462686567	2.27097167225099	0.220073180458717	0.595262492882295
GO:0050840	extracellular matrix binding	2/245	67/18639	0.0298507462686567	2.27097167225099	0.220073180458717	0.595262492882295
GO:0003756	protein disulfide isomerase activity	1/245	19/18639	0.0526315789473684	4.00408163265306	0.222384699434287	0.595262492882295
GO:0008301	DNA binding, bending	1/245	19/18639	0.0526315789473684	4.00408163265306	0.222384699434287	0.595262492882295
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/245	19/18639	0.0526315789473684	4.00408163265306	0.222384699434287	0.595262492882295
GO:0016918	retinal binding	1/245	19/18639	0.0526315789473684	4.00408163265306	0.222384699434287	0.595262492882295
GO:0043395	heparan sulfate proteoglycan binding	1/245	19/18639	0.0526315789473684	4.00408163265306	0.222384699434287	0.595262492882295
GO:0140036	ubiquitin-modified protein reader activity	1/245	19/18639	0.0526315789473684	4.00408163265306	0.222384699434287	0.595262492882295
GO:0002039	p53 binding	2/245	69/18639	0.0289855072463768	2.20514640638864	0.229763668887728	0.60490760539747
GO:0008080	N-acetyltransferase activity	2/245	69/18639	0.0289855072463768	2.20514640638864	0.229763668887728	0.60490760539747
GO:0010851	cyclase regulator activity	1/245	20/18639	0.05	3.80387755102041	0.232616479704889	0.60490760539747
GO:0015095	magnesium ion transmembrane transporter activity	1/245	20/18639	0.05	3.80387755102041	0.232616479704889	0.60490760539747
GO:0031418	L-ascorbic acid binding	1/245	20/18639	0.05	3.80387755102041	0.232616479704889	0.60490760539747
GO:0052745	inositol phosphate phosphatase activity	1/245	20/18639	0.05	3.80387755102041	0.232616479704889	0.60490760539747
GO:0140299	molecular sensor activity	2/245	71/18639	0.028169014084507	2.14302960620868	0.239481878469749	0.60490760539747
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/245	21/18639	0.0476190476190476	3.62274052478134	0.242714173591365	0.60490760539747
GO:0008373	sialyltransferase activity	1/245	21/18639	0.0476190476190476	3.62274052478134	0.242714173591365	0.60490760539747
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/245	21/18639	0.0476190476190476	3.62274052478134	0.242714173591365	0.60490760539747
GO:0010314	phosphatidylinositol-5-phosphate binding	1/245	21/18639	0.0476190476190476	3.62274052478134	0.242714173591365	0.60490760539747
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/245	21/18639	0.0476190476190476	3.62274052478134	0.242714173591365	0.60490760539747
GO:0061891	calcium ion sensor activity	1/245	21/18639	0.0476190476190476	3.62274052478134	0.242714173591365	0.60490760539747
GO:0072542	protein phosphatase activator activity	1/245	21/18639	0.0476190476190476	3.62274052478134	0.242714173591365	0.60490760539747
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	3/245	130/18639	0.0230769230769231	1.75563579277865	0.244296634654248	0.60490760539747
GO:0005518	collagen binding	2/245	72/18639	0.0277777777777778	2.11326530612245	0.24434885673793	0.60490760539747
GO:0003713	transcription coactivator activity	5/245	256/18639	0.01953125	1.48588966836735	0.24771391048649	0.60490760539747
GO:0008236	serine-type peptidase activity	4/245	194/18639	0.0206185567010309	1.56860929938986	0.251992747591675	0.60490760539747
GO:0008970	phospholipase A1 activity	1/245	22/18639	0.0454545454545455	3.45807050092764	0.252679531173818	0.60490760539747
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/245	22/18639	0.0454545454545455	3.45807050092764	0.252679531173818	0.60490760539747
GO:0140035	ubiquitin-like protein reader activity	1/245	22/18639	0.0454545454545455	3.45807050092764	0.252679531173818	0.60490760539747
GO:0140784	metal ion sensor activity	1/245	22/18639	0.0454545454545455	3.45807050092764	0.252679531173818	0.60490760539747
GO:0035064	methylated histone binding	2/245	74/18639	0.027027027027027	2.0561500275786	0.25409373496438	0.60490760539747
GO:0048029	monosaccharide binding	2/245	74/18639	0.027027027027027	2.0561500275786	0.25409373496438	0.60490760539747
GO:0044183	protein folding chaperone	2/245	75/18639	0.0266666666666667	2.02873469387755	0.258969777488805	0.60490760539747
GO:0016758	hexosyltransferase activity	4/245	197/18639	0.0203045685279188	1.54472184813011	0.260617063620022	0.60490760539747
GO:0004602	glutathione peroxidase activity	1/245	23/18639	0.0434782608695652	3.30771960958296	0.262514279783283	0.60490760539747
GO:0099186	structural constituent of postsynapse	1/245	23/18639	0.0434782608695652	3.30771960958296	0.262514279783283	0.60490760539747
GO:0140103	catalytic activity, acting on a glycoprotein	1/245	23/18639	0.0434782608695652	3.30771960958296	0.262514279783283	0.60490760539747
GO:0017171	serine hydrolase activity	4/245	198/18639	0.0202020202020202	1.53692022263451	0.263504765214139	0.60490760539747
GO:0017022	myosin binding	2/245	76/18639	0.0263157894736842	2.00204081632653	0.263847023285486	0.60490760539747
GO:0140034	methylation-dependent protein binding	2/245	76/18639	0.0263157894736842	2.00204081632653	0.263847023285486	0.60490760539747
GO:0002020	protease binding	3/245	136/18639	0.0220588235294118	1.678181272509	0.265468921531055	0.60490760539747
GO:0044325	transmembrane transporter binding	3/245	136/18639	0.0220588235294118	1.678181272509	0.265468921531055	0.60490760539747
GO:0016922	nuclear receptor binding	3/245	137/18639	0.0218978102189781	1.66593177416952	0.269020390345283	0.60490760539747
GO:0016829	lyase activity	4/245	200/18639	0.02	1.52155102040816	0.269298276251751	0.60490760539747
GO:0004806	triacylglycerol lipase activity	1/245	24/18639	0.0416666666666667	3.16989795918367	0.272220124296235	0.60490760539747
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/245	24/18639	0.0416666666666667	3.16989795918367	0.272220124296235	0.60490760539747
GO:0030552	cAMP binding	1/245	24/18639	0.0416666666666667	3.16989795918367	0.272220124296235	0.60490760539747
GO:0035035	histone acetyltransferase binding	1/245	24/18639	0.0416666666666667	3.16989795918367	0.272220124296235	0.60490760539747
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/245	24/18639	0.0416666666666667	3.16989795918367	0.272220124296235	0.60490760539747
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/245	24/18639	0.0416666666666667	3.16989795918367	0.272220124296235	0.60490760539747
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/245	24/18639	0.0416666666666667	3.16989795918367	0.272220124296235	0.60490760539747
GO:0050431	transforming growth factor beta binding	1/245	24/18639	0.0416666666666667	3.16989795918367	0.272220124296235	0.60490760539747
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/245	24/18639	0.0416666666666667	3.16989795918367	0.272220124296235	0.60490760539747
GO:0016757	glycosyltransferase activity	5/245	267/18639	0.0187265917602996	1.42467324008255	0.275049370659223	0.60490760539747
GO:0046332	SMAD binding	2/245	79/18639	0.0253164556962025	1.92601394988375	0.278477387651452	0.60490760539747
GO:0003714	transcription corepressor activity	4/245	204/18639	0.0196078431372549	1.49171668667467	0.28095178856294	0.60490760539747
GO:0000030	mannosyltransferase activity	1/245	25/18639	0.04	3.04310204081633	0.281798747425293	0.60490760539747
GO:0003707	nuclear steroid receptor activity	1/245	25/18639	0.04	3.04310204081633	0.281798747425293	0.60490760539747
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/245	25/18639	0.04	3.04310204081633	0.281798747425293	0.60490760539747
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/245	25/18639	0.04	3.04310204081633	0.281798747425293	0.60490760539747
GO:0019211	phosphatase activator activity	1/245	25/18639	0.04	3.04310204081633	0.281798747425293	0.60490760539747
GO:0042974	nuclear retinoic acid receptor binding	1/245	25/18639	0.04	3.04310204081633	0.281798747425293	0.60490760539747
GO:0000049	tRNA binding	2/245	80/18639	0.025	1.9019387755102	0.283350964599662	0.60490760539747
GO:0020037	heme binding	3/245	142/18639	0.0211267605633803	1.60727220465651	0.286852375107166	0.60490760539747
GO:0030971	receptor tyrosine kinase binding	2/245	81/18639	0.0246913580246914	1.87845804988662	0.28822161306915	0.60490760539747
GO:0004435	phosphatidylinositol phospholipase C activity	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0004529	DNA exonuclease activity	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0005160	transforming growth factor beta receptor binding	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0008157	protein phosphatase 1 binding	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0008198	ferrous iron binding	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0034237	protein kinase A regulatory subunit binding	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0043548	phosphatidylinositol 3-kinase binding	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0070006	metalloaminopeptidase activity	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0070412	R-SMAD binding	1/245	26/18639	0.0384615384615385	2.92605965463108	0.291251810006189	0.60490760539747
GO:0008194	UDP-glycosyltransferase activity	3/245	145/18639	0.0206896551724138	1.57401829697396	0.297598078589653	0.614709735748651
GO:0001540	amyloid-beta binding	2/245	83/18639	0.0240963855421687	1.83319400049176	0.297951095749346	0.614709735748651
GO:0005044	scavenger receptor activity	1/245	27/18639	0.037037037037037	2.81768707482993	0.300580951281023	0.616042147674968
GO:0035255	ionotropic glutamate receptor binding	1/245	27/18639	0.037037037037037	2.81768707482993	0.300580951281023	0.616042147674968
GO:0051117	ATPase binding	2/245	84/18639	0.0238095238095238	1.81137026239067	0.302808466104052	0.61653789328071
GO:0180051	translation factor activity	2/245	84/18639	0.0238095238095238	1.81137026239067	0.302808466104052	0.61653789328071
GO:0005242	inward rectifier potassium channel activity	1/245	28/18639	0.0357142857142857	2.71705539358601	0.309787789177872	0.622583226794365
GO:0019789	SUMO transferase activity	1/245	28/18639	0.0357142857142857	2.71705539358601	0.309787789177872	0.622583226794365
GO:0046875	ephrin receptor binding	1/245	28/18639	0.0357142857142857	2.71705539358601	0.309787789177872	0.622583226794365
GO:0097718	disordered domain specific binding	1/245	28/18639	0.0357142857142857	2.71705539358601	0.309787789177872	0.622583226794365
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/245	86/18639	0.0232558139534884	1.76924537256763	0.312504952713587	0.626017985919799
GO:0031267	small GTPase binding	5/245	283/18639	0.0176678445229682	1.34412634311675	0.315818837168858	0.63062217968444
GO:0004181	metallocarboxypeptidase activity	1/245	29/18639	0.0344827586206897	2.62336382828994	0.318873920586793	0.632654008576352
GO:0004629	phospholipase C activity	1/245	29/18639	0.0344827586206897	2.62336382828994	0.318873920586793	0.632654008576352
GO:0016651	oxidoreductase activity, acting on NAD(P)H	2/245	88/18639	0.0227272727272727	1.72903525046382	0.322172639950209	0.636270068430681
GO:0046906	tetrapyrrole binding	3/245	152/18639	0.0197368421052632	1.5015306122449	0.322745686885128	0.636270068430681
GO:0001965	G-protein alpha-subunit binding	1/245	30/18639	0.0333333333333333	2.53591836734694	0.327840921632265	0.638210696970647
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/245	30/18639	0.0333333333333333	2.53591836734694	0.327840921632265	0.638210696970647
GO:0033612	receptor serine/threonine kinase binding	1/245	30/18639	0.0333333333333333	2.53591836734694	0.327840921632265	0.638210696970647
GO:0098918	structural constituent of synapse	1/245	30/18639	0.0333333333333333	2.53591836734694	0.327840921632265	0.638210696970647
GO:0005506	iron ion binding	3/245	154/18639	0.0194805194805195	1.48203021468328	0.329937822248159	0.639402770862558
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/245	91/18639	0.021978021978022	1.67203408836062	0.336609103641159	0.639402770862558
GO:0072341	modified amino acid binding	2/245	91/18639	0.021978021978022	1.67203408836062	0.336609103641159	0.639402770862558
GO:0005184	neuropeptide hormone activity	1/245	31/18639	0.032258064516129	2.45411454904542	0.33669034794212	0.639402770862558
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/245	31/18639	0.032258064516129	2.45411454904542	0.33669034794212	0.639402770862558
GO:0005452	solute:inorganic anion antiporter activity	1/245	31/18639	0.032258064516129	2.45411454904542	0.33669034794212	0.639402770862558
GO:0047499	calcium-independent phospholipase A2 activity	1/245	31/18639	0.032258064516129	2.45411454904542	0.33669034794212	0.639402770862558
GO:0070273	phosphatidylinositol-4-phosphate binding	1/245	31/18639	0.032258064516129	2.45411454904542	0.33669034794212	0.639402770862558
GO:0043178	alcohol binding	2/245	92/18639	0.0217391304347826	1.65385980479148	0.341401518286904	0.646108853557152
GO:0015106	bicarbonate transmembrane transporter activity	1/245	32/18639	0.03125	2.37742346938776	0.345423734913002	0.646108853557152
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/245	32/18639	0.03125	2.37742346938776	0.345423734913002	0.646108853557152
GO:0047498	calcium-dependent phospholipase A2 activity	1/245	32/18639	0.03125	2.37742346938776	0.345423734913002	0.646108853557152
GO:0160041	neuropeptide activity	1/245	32/18639	0.03125	2.37742346938776	0.345423734913002	0.646108853557152
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/245	33/18639	0.0303030303030303	2.30538033395176	0.354042597972406	0.650701088994165
GO:0019239	deaminase activity	1/245	33/18639	0.0303030303030303	2.30538033395176	0.354042597972406	0.650701088994165
GO:0071889	14-3-3 protein binding	1/245	33/18639	0.0303030303030303	2.30538033395176	0.354042597972406	0.650701088994165
GO:0140311	protein sequestering activity	1/245	33/18639	0.0303030303030303	2.30538033395176	0.354042597972406	0.650701088994165
GO:0140416	transcription regulator inhibitor activity	1/245	33/18639	0.0303030303030303	2.30538033395176	0.354042597972406	0.650701088994165
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4/245	229/18639	0.0174672489082969	1.32886552000713	0.355032547374992	0.650701088994165
GO:0016407	acetyltransferase activity	2/245	96/18639	0.0208333333333333	1.58494897959184	0.36045767403959	0.650701088994165
GO:0008175	tRNA methyltransferase activity	1/245	34/18639	0.0294117647058824	2.237575030012	0.362548432837329	0.650701088994165
GO:0015020	glucuronosyltransferase activity	1/245	34/18639	0.0294117647058824	2.237575030012	0.362548432837329	0.650701088994165
GO:0015035	protein-disulfide reductase activity	1/245	34/18639	0.0294117647058824	2.237575030012	0.362548432837329	0.650701088994165
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/245	34/18639	0.0294117647058824	2.237575030012	0.362548432837329	0.650701088994165
GO:0019825	oxygen binding	1/245	34/18639	0.0294117647058824	2.237575030012	0.362548432837329	0.650701088994165
GO:0030332	cyclin binding	1/245	34/18639	0.0294117647058824	2.237575030012	0.362548432837329	0.650701088994165
GO:0090482	vitamin transmembrane transporter activity	1/245	34/18639	0.0294117647058824	2.237575030012	0.362548432837329	0.650701088994165
GO:0061659	ubiquitin-like protein ligase activity	6/245	372/18639	0.0161290322580645	1.22705727452271	0.364344192937524	0.652039607533725
GO:0004623	phospholipase A2 activity	1/245	35/18639	0.0285714285714286	2.1736443148688	0.370942715769597	0.656283266361595
GO:0016229	steroid dehydrogenase activity	1/245	35/18639	0.0285714285714286	2.1736443148688	0.370942715769597	0.656283266361595
GO:0043015	gamma-tubulin binding	1/245	35/18639	0.0285714285714286	2.1736443148688	0.370942715769597	0.656283266361595
GO:0140566	histone reader activity	1/245	35/18639	0.0285714285714286	2.1736443148688	0.370942715769597	0.656283266361595
GO:0004033	aldo-keto reductase (NADPH) activity	1/245	36/18639	0.0277777777777778	2.11326530612245	0.379226903827888	0.669033827491814
GO:0030280	structural constituent of skin epidermis	1/245	37/18639	0.027027027027027	2.0561500275786	0.387402435116507	0.677681442837608
GO:0030551	cyclic nucleotide binding	1/245	37/18639	0.027027027027027	2.0561500275786	0.387402435116507	0.677681442837608
GO:0043394	proteoglycan binding	1/245	37/18639	0.027027027027027	2.0561500275786	0.387402435116507	0.677681442837608
GO:0008238	exopeptidase activity	2/245	102/18639	0.0196078431372549	1.49171668667467	0.388646404340759	0.677947800830369
GO:0022804	active transmembrane transporter activity	7/245	457/18639	0.0153172866520788	1.16530165676774	0.394810846090049	0.678418018586241
GO:0015631	tubulin binding	6/245	385/18639	0.0155844155844156	1.18562417174662	0.394825701075584	0.678418018586241
GO:0000146	microfilament motor activity	1/245	38/18639	0.0263157894736842	2.00204081632653	0.395470729030949	0.678418018586241
GO:0005501	retinoid binding	1/245	38/18639	0.0263157894736842	2.00204081632653	0.395470729030949	0.678418018586241
GO:0019840	isoprenoid binding	1/245	38/18639	0.0263157894736842	2.00204081632653	0.395470729030949	0.678418018586241
GO:0042887	amide transmembrane transporter activity	1/245	38/18639	0.0263157894736842	2.00204081632653	0.395470729030949	0.678418018586241
GO:0051020	GTPase binding	5/245	315/18639	0.0158730158730159	1.20758017492711	0.398980676747692	0.682553719725391
GO:0000217	DNA secondary structure binding	1/245	39/18639	0.0256410256410256	1.95070643642072	0.403433186500301	0.685866930161836
GO:0000149	SNARE binding	2/245	106/18639	0.0188679245283019	1.4354254909511	0.40713368470994	0.685866930161836
GO:0004177	aminopeptidase activity	1/245	40/18639	0.025	1.9019387755102	0.411291190226507	0.685866930161836
GO:0030331	nuclear estrogen receptor binding	1/245	40/18639	0.025	1.9019387755102	0.411291190226507	0.685866930161836
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/245	40/18639	0.025	1.9019387755102	0.411291190226507	0.685866930161836
GO:0050997	quaternary ammonium group binding	1/245	40/18639	0.025	1.9019387755102	0.411291190226507	0.685866930161836
GO:0071855	neuropeptide receptor binding	1/245	40/18639	0.025	1.9019387755102	0.411291190226507	0.685866930161836
GO:0140662	ATP-dependent protein folding chaperone	1/245	40/18639	0.025	1.9019387755102	0.411291190226507	0.685866930161836
GO:0019888	protein phosphatase regulator activity	2/245	107/18639	0.0186915887850467	1.42201029944688	0.411713745358996	0.685866930161836
GO:0043021	ribonucleoprotein complex binding	3/245	177/18639	0.0169491525423729	1.28945001729505	0.411961940338752	0.685866930161836
GO:0001530	lipopolysaccharide binding	1/245	41/18639	0.024390243902439	1.855550024888	0.41904610492055	0.692094763711866
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/245	41/18639	0.024390243902439	1.855550024888	0.41904610492055	0.692094763711866
GO:0042169	SH2 domain binding	1/245	41/18639	0.024390243902439	1.855550024888	0.41904610492055	0.692094763711866
GO:0008307	structural constituent of muscle	1/245	42/18639	0.0238095238095238	1.81137026239067	0.426699277535587	0.699156336014775
GO:0031492	nucleosomal DNA binding	1/245	42/18639	0.0238095238095238	1.81137026239067	0.426699277535587	0.699156336014775
GO:0035198	miRNA binding	1/245	42/18639	0.0238095238095238	1.81137026239067	0.426699277535587	0.699156336014775
GO:1902936	phosphatidylinositol bisphosphate binding	2/245	111/18639	0.018018018018018	1.3707666850524	0.429856562940565	0.702476119963397
GO:0005200	structural constituent of cytoskeleton	2/245	112/18639	0.0178571428571429	1.358527696793	0.434346327528058	0.707950313372504
GO:0015078	proton transmembrane transporter activity	3/245	185/18639	0.0162162162162162	1.23369001654716	0.439845772249104	0.71383720033138
GO:0003954	NADH dehydrogenase activity	1/245	44/18639	0.0227272727272727	1.72903525046382	0.441705696929921	0.71383720033138
GO:0043014	alpha-tubulin binding	1/245	44/18639	0.0227272727272727	1.72903525046382	0.441705696929921	0.71383720033138
GO:0035401	histone H3Y41 kinase activity	2/245	115/18639	0.0173913043478261	1.32308784383319	0.447700700554601	0.71383720033138
GO:0140801	histone H2AXY142 kinase activity	2/245	115/18639	0.0173913043478261	1.32308784383319	0.447700700554601	0.71383720033138
GO:0046915	transition metal ion transmembrane transporter activity	1/245	45/18639	0.0222222222222222	1.69061224489796	0.449061550882713	0.71383720033138
GO:0051539	4 iron, 4 sulfur cluster binding	1/245	45/18639	0.0222222222222222	1.69061224489796	0.449061550882713	0.71383720033138
GO:0009055	electron transfer activity	2/245	116/18639	0.0172413793103448	1.31168191414497	0.452112959646359	0.71383720033138
GO:0004180	carboxypeptidase activity	1/245	46/18639	0.0217391304347826	1.65385980479148	0.456320877549043	0.71383720033138
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/245	46/18639	0.0217391304347826	1.65385980479148	0.456320877549043	0.71383720033138
GO:0030276	clathrin binding	1/245	46/18639	0.0217391304347826	1.65385980479148	0.456320877549043	0.71383720033138
GO:0019208	phosphatase regulator activity	2/245	117/18639	0.0170940170940171	1.30047095761381	0.456505199216384	0.71383720033138
GO:1990782	protein tyrosine kinase binding	2/245	117/18639	0.0170940170940171	1.30047095761381	0.456505199216384	0.71383720033138
GO:0001784	phosphotyrosine residue binding	1/245	47/18639	0.0212765957446809	1.61867129830656	0.463484938485981	0.71383720033138
GO:0043495	protein-membrane adaptor activity	1/245	47/18639	0.0212765957446809	1.61867129830656	0.463484938485981	0.71383720033138
GO:0016887	ATP hydrolysis activity	6/245	417/18639	0.0143884892086331	1.09464102187638	0.46932450569112	0.71383720033138
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/245	48/18639	0.0208333333333333	1.58494897959184	0.470554978829727	0.71383720033138
GO:0032266	phosphatidylinositol-3-phosphate binding	1/245	48/18639	0.0208333333333333	1.58494897959184	0.470554978829727	0.71383720033138
GO:0038187	pattern recognition receptor activity	1/245	48/18639	0.0208333333333333	1.58494897959184	0.470554978829727	0.71383720033138
GO:0140693	molecular condensate scaffold activity	1/245	48/18639	0.0208333333333333	1.58494897959184	0.470554978829727	0.71383720033138
GO:0051082	unfolded protein binding	2/245	121/18639	0.0165289256198347	1.25748018215551	0.473869360730068	0.71383720033138
GO:0005004	GPI-linked ephrin receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0005008	hepatocyte growth factor receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0005009	insulin receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0005011	macrophage colony-stimulating factor receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0005020	stem cell factor receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0008288	boss receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0035254	glutamate receptor binding	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0036332	placental growth factor receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0038062	protein tyrosine kinase collagen receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0060175	brain-derived neurotrophic factor receptor activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0060590	ATPase regulator activity	1/245	49/18639	0.0204081632653061	1.55260308204915	0.477532227508481	0.71383720033138
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/245	122/18639	0.0163934426229508	1.24717296754767	0.478158133616227	0.71383720033138
GO:0016755	aminoacyltransferase activity	7/245	496/18639	0.0141129032258065	1.07367511520737	0.478190459481246	0.71383720033138
GO:0005006	epidermal growth factor receptor activity	1/245	50/18639	0.02	1.52155102040816	0.48441789745256	0.716246462661999
GO:0005007	fibroblast growth factor receptor activity	1/245	50/18639	0.02	1.52155102040816	0.48441789745256	0.716246462661999
GO:0005017	platelet-derived growth factor receptor activity	1/245	50/18639	0.02	1.52155102040816	0.48441789745256	0.716246462661999
GO:0005019	platelet-derived growth factor beta-receptor activity	1/245	50/18639	0.02	1.52155102040816	0.48441789745256	0.716246462661999
GO:0005010	insulin-like growth factor receptor activity	1/245	51/18639	0.0196078431372549	1.49171668667467	0.491213185801805	0.716974098463689
GO:0005021	vascular endothelial growth factor receptor activity	1/245	51/18639	0.0196078431372549	1.49171668667467	0.491213185801805	0.716974098463689
GO:0005030	neurotrophin receptor activity	1/245	51/18639	0.0196078431372549	1.49171668667467	0.491213185801805	0.716974098463689
GO:0016597	amino acid binding	1/245	51/18639	0.0196078431372549	1.49171668667467	0.491213185801805	0.716974098463689
GO:0008017	microtubule binding	4/245	276/18639	0.0144927536231884	1.10257320319432	0.492547644573386	0.716974098463689
GO:0061630	ubiquitin protein ligase activity	5/245	353/18639	0.0141643059490085	1.07758570850436	0.496162761873135	0.716974098463689
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/245	52/18639	0.0192307692307692	1.46302982731554	0.497919274110314	0.716974098463689
GO:0031490	chromatin DNA binding	2/245	128/18639	0.015625	1.18871173469388	0.503437318190312	0.716974098463689
GO:0030246	carbohydrate binding	4/245	280/18639	0.0142857142857143	1.0868221574344	0.503768399182425	0.716974098463689
GO:0005003	ephrin receptor activity	1/245	53/18639	0.0188679245283019	1.4354254909511	0.504537328548522	0.716974098463689
GO:0005005	transmembrane-ephrin receptor activity	1/245	53/18639	0.0188679245283019	1.4354254909511	0.504537328548522	0.716974098463689
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/245	53/18639	0.0188679245283019	1.4354254909511	0.504537328548522	0.716974098463689
GO:0017046	peptide hormone binding	1/245	53/18639	0.0188679245283019	1.4354254909511	0.504537328548522	0.716974098463689
GO:0034212	protein N-acetyltransferase activity	1/245	53/18639	0.0188679245283019	1.4354254909511	0.504537328548522	0.716974098463689
GO:0038064	collagen receptor activity	1/245	53/18639	0.0188679245283019	1.4354254909511	0.504537328548522	0.716974098463689
GO:0051018	protein kinase A binding	1/245	53/18639	0.0188679245283019	1.4354254909511	0.504537328548522	0.716974098463689
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/245	53/18639	0.0188679245283019	1.4354254909511	0.504537328548522	0.716974098463689
GO:0017069	snRNA binding	1/245	54/18639	0.0185185185185185	1.40884353741497	0.511068500102682	0.7221766054345
GO:0051287	NAD binding	1/245	54/18639	0.0185185185185185	1.40884353741497	0.511068500102682	0.7221766054345
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/245	130/18639	0.0153846153846154	1.17042386185243	0.51168712784409	0.7221766054345
GO:0035091	phosphatidylinositol binding	4/245	284/18639	0.0140845070422535	1.07151480310434	0.514880108192924	0.722193589400593
GO:0031072	heat shock protein binding	2/245	131/18639	0.0152671755725191	1.16148932855585	0.515778290491221	0.722193589400593
GO:0106310	protein serine kinase activity	5/245	361/18639	0.0138504155124654	1.05370569280344	0.515943423215836	0.722193589400593
GO:0008374	O-acyltransferase activity	1/245	55/18639	0.0181818181818182	1.38322820037106	0.517513924771761	0.722193589400593
GO:0098632	cell-cell adhesion mediator activity	1/245	55/18639	0.0181818181818182	1.38322820037106	0.517513924771761	0.722193589400593
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	2/245	132/18639	0.0151515151515152	1.15269016697588	0.519846795683666	0.723822556321876
GO:0030170	pyridoxal phosphate binding	1/245	56/18639	0.0178571428571429	1.358527696793	0.523874723761802	0.727799112877135
GO:0004601	peroxidase activity	1/245	57/18639	0.0175438596491228	1.33469387755102	0.530152003677766	0.731609765075317
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/245	57/18639	0.0175438596491228	1.33469387755102	0.530152003677766	0.731609765075317
GO:0070279	vitamin B6 binding	1/245	57/18639	0.0175438596491228	1.33469387755102	0.530152003677766	0.731609765075317
GO:0008408	3'-5' exonuclease activity	1/245	58/18639	0.0172413793103448	1.31168191414497	0.536346856712905	0.735256949268684
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/245	58/18639	0.0172413793103448	1.31168191414497	0.536346856712905	0.735256949268684
GO:0061980	regulatory RNA binding	1/245	58/18639	0.0172413793103448	1.31168191414497	0.536346856712905	0.735256949268684
GO:0004879	nuclear receptor activity	1/245	59/18639	0.0169491525423729	1.28945001729505	0.542460360835683	0.737128849188094
GO:0015459	potassium channel regulator activity	1/245	59/18639	0.0169491525423729	1.28945001729505	0.542460360835683	0.737128849188094
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	1/245	59/18639	0.0169491525423729	1.28945001729505	0.542460360835683	0.737128849188094
GO:0045309	protein phosphorylated amino acid binding	1/245	59/18639	0.0169491525423729	1.28945001729505	0.542460360835683	0.737128849188094
GO:0030295	protein kinase activator activity	2/245	139/18639	0.0143884892086331	1.09464102187638	0.547683258418445	0.737260851004398
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/245	60/18639	0.0166666666666667	1.26795918367347	0.548493579974287	0.737260851004398
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/245	60/18639	0.0166666666666667	1.26795918367347	0.548493579974287	0.737260851004398
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/245	60/18639	0.0166666666666667	1.26795918367347	0.548493579974287	0.737260851004398
GO:0098531	ligand-modulated transcription factor activity	1/245	60/18639	0.0166666666666667	1.26795918367347	0.548493579974287	0.737260851004398
GO:0004713	protein tyrosine kinase activity	2/245	140/18639	0.0142857142857143	1.0868221574344	0.551566984779375	0.739790707447067
GO:0016836	hydro-lyase activity	1/245	61/18639	0.0163934426229508	1.24717296754767	0.55444756419875	0.740455779284782
GO:0019905	syntaxin binding	1/245	61/18639	0.0163934426229508	1.24717296754767	0.55444756419875	0.740455779284782
GO:0015179	L-amino acid transmembrane transporter activity	1/245	62/18639	0.0161290322580645	1.22705727452271	0.560323349900725	0.746696996326932
GO:0005507	copper ion binding	1/245	63/18639	0.0158730158730159	1.20758017492711	0.566121959970937	0.75058498592064
GO:1901682	sulfur compound transmembrane transporter activity	1/245	63/18639	0.0158730158730159	1.20758017492711	0.566121959970937	0.75058498592064
GO:0019903	protein phosphatase binding	2/245	144/18639	0.0138888888888889	1.05663265306122	0.566866921733946	0.75058498592064
GO:0004536	DNA nuclease activity	1/245	64/18639	0.015625	1.18871173469388	0.571844403974335	0.755564627378856
GO:0019843	rRNA binding	1/245	65/18639	0.0153846153846154	1.17042386185243	0.577491678322991	0.761406225559612
GO:0019209	kinase activator activity	2/245	148/18639	0.0135135135135135	1.0280750137893	0.581788752052026	0.765446642000652
GO:0008173	RNA methyltransferase activity	1/245	67/18639	0.0149253731343284	1.1354858361255	0.588564638961729	0.771094178892899
GO:0016500	protein-hormone receptor activity	1/245	67/18639	0.0149253731343284	1.1354858361255	0.588564638961729	0.771094178892899
GO:0003777	microtubule motor activity	1/245	68/18639	0.0147058823529412	1.118787515006	0.593992253836508	0.771692865339898
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/245	68/18639	0.0147058823529412	1.118787515006	0.593992253836508	0.771692865339898
GO:0140223	general transcription initiation factor activity	1/245	68/18639	0.0147058823529412	1.118787515006	0.593992253836508	0.771692865339898
GO:1990841	promoter-specific chromatin binding	1/245	68/18639	0.0147058823529412	1.118787515006	0.593992253836508	0.771692865339898
GO:0003774	cytoskeletal motor activity	2/245	153/18639	0.0130718954248366	0.994477791116447	0.599906662390671	0.77774955604302
GO:0019787	ubiquitin-like protein transferase activity	6/245	479/18639	0.0125260960334029	0.952954710067743	0.604515157104215	0.780619568102015
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/245	70/18639	0.0142857142857143	1.0868221574344	0.604634480285136	0.780619568102015
GO:0005539	glycosaminoglycan binding	3/245	242/18639	0.012396694214876	0.94311013661663	0.619366358104086	0.797244592741481
GO:0043539	protein serine/threonine kinase activator activity	1/245	73/18639	0.0136986301369863	1.04215823315628	0.620079127687819	0.797244592741481
GO:0015079	potassium ion transmembrane transporter activity	2/245	160/18639	0.0125	0.950969387755102	0.624273177882747	0.798729466834465
GO:0003684	damaged DNA binding	1/245	74/18639	0.0135135135135135	1.0280750137893	0.625092626218277	0.798729466834465
GO:0031491	nucleosome binding	1/245	74/18639	0.0135135135135135	1.0280750137893	0.625092626218277	0.798729466834465
GO:0019003	GDP binding	1/245	75/18639	0.0133333333333333	1.01436734693878	0.630040232282188	0.80229124148349
GO:0033218	amide binding	3/245	247/18639	0.0121457489878543	0.924018838304553	0.63314350826126	0.80229124148349
GO:0042393	histone binding	3/245	247/18639	0.0121457489878543	0.924018838304553	0.63314350826126	0.80229124148349
GO:0051536	iron-sulfur cluster binding	1/245	76/18639	0.0131578947368421	1.00102040816327	0.634922808402144	0.80229124148349
GO:0098631	cell adhesion mediator activity	1/245	76/18639	0.0131578947368421	1.00102040816327	0.634922808402144	0.80229124148349
GO:0003924	GTPase activity	4/245	331/18639	0.0120845921450151	0.91936617547321	0.635631708228466	0.80229124148349
GO:0015081	sodium ion transmembrane transporter activity	2/245	164/18639	0.0121951219512195	0.927775012444002	0.63767563732685	0.802584421892448
GO:0042277	peptide binding	3/245	249/18639	0.0120481927710843	0.916597000245882	0.63855711474513	0.802584421892448
GO:0051540	metal cluster binding	1/245	77/18639	0.012987012987013	0.988020143122184	0.639741205856299	0.802584421892448
GO:0019199	transmembrane receptor protein kinase activity	1/245	78/18639	0.0128205128205128	0.975353218210361	0.644496264824364	0.80484246480205
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/245	167/18639	0.0119760479041916	0.91110839545399	0.647480266036478	0.80484246480205
GO:0015370	solute:sodium symporter activity	1/245	79/18639	0.0126582278481013	0.963006974941875	0.649188814531708	0.80484246480205
GO:0016835	carbon-oxygen lyase activity	1/245	79/18639	0.0126582278481013	0.963006974941875	0.649188814531708	0.80484246480205
GO:0015101	organic cation transmembrane transporter activity	1/245	81/18639	0.0123456790123457	0.939229024943311	0.658389649145638	0.80484246480205
GO:0033192	calmodulin-dependent protein phosphatase activity	1/245	81/18639	0.0123456790123457	0.939229024943311	0.658389649145638	0.80484246480205
GO:0140791	histone H2AXS140 phosphatase activity	1/245	81/18639	0.0123456790123457	0.939229024943311	0.658389649145638	0.80484246480205
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	1/245	81/18639	0.0123456790123457	0.939229024943311	0.658389649145638	0.80484246480205
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	1/245	81/18639	0.0123456790123457	0.939229024943311	0.658389649145638	0.80484246480205
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	1/245	81/18639	0.0123456790123457	0.939229024943311	0.658389649145638	0.80484246480205
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	1/245	81/18639	0.0123456790123457	0.939229024943311	0.658389649145638	0.80484246480205
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	1/245	81/18639	0.0123456790123457	0.939229024943311	0.658389649145638	0.80484246480205
GO:1990439	MAP kinase serine/threonine phosphatase activity	1/245	81/18639	0.0123456790123457	0.939229024943311	0.658389649145638	0.80484246480205
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	1/245	82/18639	0.0121951219512195	0.927775012444002	0.662899539002267	0.806150554995247
GO:0033549	MAP kinase phosphatase activity	1/245	82/18639	0.0121951219512195	0.927775012444002	0.662899539002267	0.806150554995247
GO:0008201	heparin binding	2/245	172/18639	0.0116279069767442	0.884622686283816	0.663354160390613	0.806150554995247
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	1/245	83/18639	0.0120481927710843	0.916597000245882	0.667350129773644	0.806273211263489
GO:0005254	chloride channel activity	1/245	83/18639	0.0120481927710843	0.916597000245882	0.667350129773644	0.806273211263489
GO:0008135	translation factor activity, RNA binding	1/245	83/18639	0.0120481927710843	0.916597000245882	0.667350129773644	0.806273211263489
GO:0004527	exonuclease activity	1/245	84/18639	0.0119047619047619	0.905685131195335	0.671742198010628	0.80790142859866
GO:0017018	myosin phosphatase activity	1/245	84/18639	0.0119047619047619	0.905685131195335	0.671742198010628	0.80790142859866
GO:0004721	phosphoprotein phosphatase activity	2/245	175/18639	0.0114285714285714	0.869457725947522	0.672600706256856	0.80790142859866
GO:0016209	antioxidant activity	1/245	86/18639	0.0116279069767442	0.884622686283816	0.680353822576324	0.815486840613651
GO:0005319	lipid transporter activity	2/245	178/18639	0.0112359550561798	0.85480394404953	0.681641066265884	0.815486840613651
GO:0008081	phosphoric diester hydrolase activity	1/245	87/18639	0.0114942528735632	0.874454609429979	0.684574881891195	0.815486840613651
GO:0141003	histone H2AX kinase activity	4/245	354/18639	0.0112994350282486	0.859633344863369	0.687160451993189	0.815486840613651
GO:0004197	cysteine-type endopeptidase activity	1/245	88/18639	0.0113636363636364	0.864517625231911	0.688740424902011	0.815486840613651
GO:0008514	organic anion transmembrane transporter activity	3/245	269/18639	0.0111524163568773	0.848448524391169	0.689611213613305	0.815486840613651
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	1/245	89/18639	0.0112359550561798	0.85480394404953	0.692851178818189	0.815486840613651
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	1/245	89/18639	0.0112359550561798	0.85480394404953	0.692851178818189	0.815486840613651
GO:0140996	histone H3 kinase activity	4/245	357/18639	0.0112044817927171	0.852409535242668	0.69348990138389	0.815486840613651
GO:0140793	histone H2AXY142 phosphatase activity	1/245	90/18639	0.0111111111111111	0.84530612244898	0.696907861362099	0.815486840613651
GO:0016791	phosphatase activity	3/245	273/18639	0.010989010989011	0.83601704418031	0.699149238937339	0.815486840613651
GO:0035173	histone kinase activity	4/245	360/18639	0.0111111111111111	0.84530612244898	0.699728279843107	0.815486840613651
GO:1901981	phosphatidylinositol phosphate binding	2/245	185/18639	0.0108108108108108	0.82246001103144	0.701944777842048	0.815486840613651
GO:0005126	cytokine receptor binding	3/245	275/18639	0.0109090909090909	0.829936920222635	0.703834609290071	0.815486840613651
GO:1901681	sulfur compound binding	3/245	275/18639	0.0109090909090909	0.829936920222635	0.703834609290071	0.815486840613651
GO:0052689	carboxylic ester hydrolase activity	1/245	92/18639	0.0108695652173913	0.826929902395741	0.704861836525358	0.815486840613651
GO:0042578	phosphoric ester hydrolase activity	4/245	363/18639	0.0110192837465565	0.838320121437005	0.705875554775218	0.815486840613651
GO:0004842	ubiquitin-protein transferase activity	5/245	449/18639	0.0111358574610245	0.847188764147084	0.706532434275714	0.815486840613651
GO:0031406	carboxylic acid binding	2/245	187/18639	0.0106951871657754	0.813663647277093	0.707545528877463	0.815486840613651
GO:0046873	metal ion transmembrane transporter activity	5/245	450/18639	0.0111111111111111	0.84530612244898	0.708365715302629	0.815486840613651
GO:0051213	dioxygenase activity	1/245	93/18639	0.010752688172043	0.818038183015142	0.708760518255627	0.815486840613651
GO:0051219	phosphoprotein binding	1/245	93/18639	0.010752688172043	0.818038183015142	0.708760518255627	0.815486840613651
GO:0046943	carboxylic acid transmembrane transporter activity	2/245	188/18639	0.0106382978723404	0.809335649153278	0.710312956784769	0.815486840613651
GO:0042562	hormone binding	1/245	94/18639	0.0106382978723404	0.809335649153278	0.712607907074098	0.815486840613651
GO:0005342	organic acid transmembrane transporter activity	2/245	189/18639	0.0105820105820106	0.805053449951409	0.713058541792613	0.815486840613651
GO:0043177	organic acid binding	2/245	189/18639	0.0105820105820106	0.805053449951409	0.713058541792613	0.815486840613651
GO:0019902	phosphatase binding	2/245	190/18639	0.0105263157894737	0.800816326530612	0.715782377264835	0.816306978399893
GO:0008276	protein methyltransferase activity	1/245	95/18639	0.0105263157894737	0.800816326530612	0.716404675085252	0.816306978399893
GO:0046982	protein heterodimerization activity	4/245	369/18639	0.010840108401084	0.824688899950224	0.717896967615503	0.816509188441809
GO:0004725	protein tyrosine phosphatase activity	1/245	98/18639	0.0102040816326531	0.776301541024573	0.727497844437207	0.822907397806021
GO:0005249	voltage-gated potassium channel activity	1/245	98/18639	0.0102040816326531	0.776301541024573	0.727497844437207	0.822907397806021
GO:0008170	N-methyltransferase activity	1/245	98/18639	0.0102040816326531	0.776301541024573	0.727497844437207	0.822907397806021
GO:0015291	secondary active transmembrane transporter activity	3/245	287/18639	0.0104529616724739	0.795235724952002	0.730785999336771	0.825123828342064
GO:0005525	GTP binding	4/245	378/18639	0.0105820105820106	0.805053449951409	0.735248391432431	0.828655628093539
GO:0015171	amino acid transmembrane transporter activity	1/245	102/18639	0.00980392156862745	0.745858343337335	0.741619311845424	0.834321725826102
GO:0004722	protein serine/threonine phosphatase activity	1/245	103/18639	0.00970873786407767	0.738617000198137	0.74503428021128	0.835137703991345
GO:0005253	monoatomic anion channel activity	1/245	103/18639	0.00970873786407767	0.738617000198137	0.74503428021128	0.835137703991345
GO:0008168	methyltransferase activity	2/245	204/18639	0.00980392156862745	0.745858343337335	0.751687508258854	0.841077374105853
GO:0005516	calmodulin binding	2/245	207/18639	0.00966183574879227	0.735048802129547	0.758856043491566	0.847571228432126
GO:0005496	steroid binding	1/245	108/18639	0.00925925925925926	0.704421768707483	0.761446496424892	0.848937655798668
GO:0019001	guanyl nucleotide binding	4/245	400/18639	0.01	0.760775510204082	0.774272724415841	0.860149126766078
GO:0032561	guanyl ribonucleotide binding	4/245	400/18639	0.01	0.760775510204082	0.774272724415841	0.860149126766078
GO:0016741	transferase activity, transferring one-carbon groups	2/245	215/18639	0.00930232558139535	0.707698149027053	0.777105285299529	0.861754253876799
GO:0001221	transcription coregulator binding	1/245	115/18639	0.00869565217391304	0.661543921916593	0.782670730946897	0.86637883051341
GO:0015294	solute:monoatomic cation symporter activity	1/245	116/18639	0.00862068965517241	0.655840957072484	0.785545146349511	0.868013409044566
GO:0015108	chloride transmembrane transporter activity	1/245	121/18639	0.00826446280991736	0.628740091077753	0.799359099688667	0.876001238062888
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/245	122/18639	0.00819672131147541	0.623586483773837	0.802013653127283	0.876001238062888
GO:0005267	potassium channel activity	1/245	124/18639	0.00806451612903226	0.613528637261356	0.807218281271632	0.876001238062888
GO:0000287	magnesium ion binding	2/245	230/18639	0.00869565217391304	0.661543921916593	0.808093782085958	0.876001238062888
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	1/245	128/18639	0.0078125	0.594355867346939	0.81722226794653	0.876001238062888
GO:0004674	protein serine/threonine kinase activity	4/245	433/18639	0.0092378752886836	0.702794928594994	0.824178740946768	0.876001238062888
GO:0051087	protein-folding chaperone binding	1/245	134/18639	0.00746268656716418	0.567742918062748	0.831267011729294	0.876001238062888
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	2/245	243/18639	0.00823045267489712	0.626152683295541	0.831795883186862	0.876001238062888
GO:0015297	antiporter activity	1/245	135/18639	0.00740740740740741	0.563537414965986	0.833500979960924	0.876001238062888
GO:0004676	3-phosphoinositide-dependent protein kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0004711	ribosomal protein S6 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0035175	histone H3S10 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0035979	histone H2AXS139 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0044022	histone H3S28 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0044023	histone H4S1 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0044024	histone H2AS1 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0044025	histone H2BS14 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0072354	histone H3T3 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0072371	histone H2AS121 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0072518	Rho-dependent protein serine/threonine kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0140823	histone H2BS36 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0140855	histone H3S57 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0140995	histone H2A kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0140997	histone H4 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0140998	histone H2B kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:1990244	histone H2AT120 kinase activity	2/245	245/18639	0.00816326530612245	0.621041232819659	0.835199696692439	0.876001238062888
GO:0099094	ligand-gated monoatomic cation channel activity	1/245	136/18639	0.00735294117647059	0.559393757503001	0.835705490332172	0.876001238062888
GO:0140789	histone phosphatase activity	1/245	136/18639	0.00735294117647059	0.559393757503001	0.835705490332172	0.876001238062888
GO:0004677	DNA-dependent protein kinase activity	2/245	246/18639	0.00813008130081301	0.618516674962668	0.836878253059242	0.876001238062888
GO:0140857	histone H3T45 kinase activity	2/245	246/18639	0.00813008130081301	0.618516674962668	0.836878253059242	0.876001238062888
GO:0035402	histone H3T11 kinase activity	2/245	247/18639	0.00809716599190283	0.616012558869702	0.838541393833103	0.876001238062888
GO:0035403	histone H3T6 kinase activity	2/245	247/18639	0.00809716599190283	0.616012558869702	0.838541393833103	0.876001238062888
GO:0004679	AMP-activated protein kinase activity	2/245	248/18639	0.00806451612903226	0.613528637261356	0.840189232158552	0.876001238062888
GO:0140101	catalytic activity, acting on a tRNA	1/245	139/18639	0.00719424460431655	0.547320510938188	0.842146117751279	0.876001238062888
GO:0140767	enzyme-substrate adaptor activity	1/245	139/18639	0.00719424460431655	0.547320510938188	0.842146117751279	0.876001238062888
GO:0022843	voltage-gated monoatomic cation channel activity	1/245	143/18639	0.00699300699300699	0.532010846296561	0.850344110597431	0.883049653312716
GO:0015293	symporter activity	1/245	146/18639	0.00684931506849315	0.521079116578138	0.85621306983356	0.887659960545311
GO:0015085	calcium ion transmembrane transporter activity	1/245	147/18639	0.00680272108843537	0.517534360683049	0.858117995907793	0.888152125764565
GO:0008509	monoatomic anion transmembrane transporter activity	1/245	149/18639	0.00671140939597315	0.510587590740994	0.8618527724734	0.890533397181334
GO:0005178	integrin binding	1/245	161/18639	0.0062111801242236	0.472531372797566	0.882292312788306	0.910138747909532
GO:0015103	inorganic anion transmembrane transporter activity	1/245	165/18639	0.00606060606060606	0.461076066790353	0.888412484486523	0.914932260142837
GO:0016874	ligase activity	1/245	167/18639	0.00598802395209581	0.455554197726995	0.891352658629304	0.916440399021188
GO:0005244	voltage-gated monoatomic ion channel activity	1/245	173/18639	0.00578034682080925	0.43975463017577	0.899718226904043	0.923512427946134
GO:0022832	voltage-gated channel activity	1/245	175/18639	0.00571428571428571	0.434728862973761	0.902361647728945	0.924697332078672
GO:0001664	G protein-coupled receptor binding	2/245	297/18639	0.00673400673400673	0.512306740878169	0.904439422612505	0.925299639937999
GO:0015276	ligand-gated monoatomic ion channel activity	1/245	186/18639	0.00537634408602151	0.409019091507571	0.915707443330925	0.934483797502478
GO:0008234	cysteine-type peptidase activity	1/245	187/18639	0.0053475935828877	0.406831823638546	0.916826593408632	0.934483797502478
GO:0022834	ligand-gated channel activity	1/245	188/18639	0.00531914893617021	0.404667824576639	0.917930944406621	0.934483797502478
GO:0004518	nuclease activity	1/245	209/18639	0.00478468899521531	0.364007421150278	0.938027346884247	0.953379676620486
GO:0003730	mRNA 3'-UTR binding	1/245	262/18639	0.00381679389312977	0.290372332138962	0.969540400600538	0.983798347668193
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	1/245	268/18639	0.00373134328358209	0.283871459031374	0.971897434625407	0.984581251064237
GO:0001217	DNA-binding transcription repressor activity	1/245	278/18639	0.00359712230215827	0.273660255469094	0.975428969688474	0.986549495401535
GO:0005216	monoatomic ion channel activity	2/245	448/18639	0.00446428571428571	0.339631924198251	0.98237053024719	0.991954632981309
GO:0022836	gated channel activity	1/245	318/18639	0.00314465408805031	0.239237581825183	0.985651293442882	0.992671235003313
GO:0030371	translation repressor activity	1/245	329/18639	0.00303951367781155	0.231238756900937	0.987626863229633	0.992671235003313
GO:0140097	catalytic activity, acting on DNA	1/245	336/18639	0.00297619047619048	0.226421282798834	0.988740466227834	0.992671235003313
GO:0005261	monoatomic cation channel activity	1/245	341/18639	0.00293255131964809	0.223101322640493	0.989474226194929	0.992671235003313
GO:0045182	translation regulator activity	1/245	356/18639	0.00280898876404494	0.213700986012382	0.991401819115935	0.993000854308058
GO:0140098	catalytic activity, acting on RNA	1/245	387/18639	0.00258397932816537	0.196582819174181	0.994342494224431	0.994342494224431