category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 4/6 370/9376 16.8936936936937 CGA/CSH1/CSH2/KISS1 7.8931652937128 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 3/6 122/9376 38.4262295081967 CSH1/CSH2/FOS 10.5288929999194 NA NA hsa04081 Hormone signaling 3/6 219/9376 21.4063926940639 CGA/CSH1/CSH2 7.73220140995266 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 3/6 298/9376 15.7315436241611 CSH1/CSH2/GDF15 6.53962381861562 Organismal Systems Endocrine system hsa04929 GnRH secretion 2/6 65/9376 48.0820512820513 CGA/KISS1 9.63840916860251 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 2/6 71/9376 44.018779342723 CGA/FOS 9.20705074313616 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 2/6 168/9376 18.6031746031746 CSH1/CSH2 5.82578496246031 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 2/6 226/9376 13.8289085545723 CGA/FOS 4.93997612472063 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 2/6 362/9376 8.63351749539595 CSH1/CSH2 3.74810442059954 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 1/6 52/9376 30.0512820512821 CGA 5.31566141176398 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/6 54/9376 28.9382716049383 CGA 5.20994733981975 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 1/6 59/9376 26.4858757062147 CGA 4.96911430252165 Human Diseases Substance dependence hsa05031 Amphetamine addiction 1/6 69/9376 22.6473429951691 FOS 4.56683956383765 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/6 75/9376 20.8355555555556 CGA 4.36416986553862 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 1/6 78/9376 20.034188034188 FOS 4.27147976803138 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/6 78/9376 20.034188034188 FOS 4.27147976803138 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/6 87/9376 17.9616858237548 FOS 4.02194037071091 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/6 90/9376 17.362962962963 FOS 3.94693823622191 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/6 91/9376 17.1721611721612 FOS 3.9227377146652 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/6 93/9376 16.8028673835125 FOS 3.87547252703018 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 1/6 93/9376 16.8028673835125 CGA 3.87547252703018 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/6 94/9376 16.6241134751773 FOS 3.85238778548876 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/6 95/9376 16.4491228070175 FOS 3.82965551164386 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/6 97/9376 16.1099656357388 FOS 3.78521214047909 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/6 99/9376 15.7845117845118 FOS 3.74207316641307 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 1/6 99/9376 15.7845117845118 FOS 3.74207316641307 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/6 103/9376 15.1715210355987 FOS 3.65945504323196 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/6 109/9376 14.3363914373089 FOS 3.54383480716902 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/6 109/9376 14.3363914373089 FOS 3.54383480716902 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/6 115/9376 13.5884057971014 FOS 3.43702095768473 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 1/6 115/9376 13.5884057971014 FOS 3.43702095768473 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/6 119/9376 13.1316526610644 FOS 3.37015429396065 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/6 122/9376 12.8087431693989 FOS 3.32208173059216 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/6 130/9376 12.0205128205128 FOS 3.20175431636381 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 1/6 133/9376 11.749373433584 FOS 3.15932251467396 Human Diseases Infectious disease: viral hsa05162 Measles 1/6 136/9376 11.4901960784314 FOS 3.11823285003157 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/6 137/9376 11.4063260340633 FOS 3.10482192354804 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/6 138/9376 11.3236714975845 FOS 3.09154953098064 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/6 139/9376 11.242206235012 FOS 3.07841320094495 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 1/6 142/9376 11.0046948356808 FOS 3.03979678478466 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/6 142/9376 11.0046948356808 FOS 3.03979678478466 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/6 148/9376 10.5585585585586 FOS 2.96593027976408 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/6 154/9376 10.1471861471861 FOS 2.89618824557166 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 1/6 157/9376 9.95329087048832 FOS 2.86274114870784 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 1/6 163/9376 9.58691206543967 FOS 2.79847705274686 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/6 196/9376 7.97278911564626 FOS 2.49634550653216 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/6 200/9376 7.81333333333333 FOS 2.46456002557695 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/6 214/9376 7.30218068535826 FOS 2.35990250499743 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/6 216/9376 7.23456790123457 FOS 2.345724295037 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/6 217/9376 7.20122887864823 FOS 2.33870296475859 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/6 224/9376 6.97619047619048 FOS 2.29077219179407 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/6 227/9376 6.88399412628488 FOS 2.27085713856627 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/6 238/9376 6.56582633053221 FOS 2.20081744874923 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/6 248/9376 6.3010752688172 FOS 2.14088561158939 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/6 300/9376 5.20888888888889 FOS 1.87487497608335