category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/9	59/9376	35.3145009416196	CGA/IRS2	8.19544005317858
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/9	71/9376	29.3458528951487	FOS/CGA	7.43134026886169
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/9	94/9376	22.1654846335697	FOS/TNFAIP3	6.39260683313236
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/9	119/9376	17.5088702147526	FOS/TNFAIP3	5.61774904984443
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/9	122/9376	17.0783242258652	FOS/IRS2	5.54067380395851
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/9	136/9376	15.3202614379085	FOS/TNFAIP3	5.21424037471944
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/9	142/9376	14.6729264475743	FOS/DUSP1	5.08882302324945
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/9	157/9376	13.2710544939844	FOS/IRS2	4.80614020894215
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/9	168/9376	12.4021164021164	FTH1/TNFAIP3	4.62236343109941
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/9	216/9376	9.64609053497942	FOS/OLR1	3.98479102312583
NA	NA	hsa04081	Hormone signaling	2/9	219/9376	9.51395230847286	CGA/IRS2	3.95169389704906
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/9	226/9376	9.21927236971485	FOS/CGA	3.87689177484626
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/9	300/9376	6.94518518518518	FOS/DUSP1	3.24403404596613
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/9	42/9376	24.8042328042328	FTH1	4.79238354948061
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/9	46/9376	22.6473429951691	FTH1	4.56193743928358
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/9	47/9376	22.1654846335697	IRS2	4.50885461868532
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/9	52/9376	20.034188034188	CGA	4.26620310528181
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/9	54/9376	19.2921810699588	CGA	4.17844274009506
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/9	61/9376	17.0783242258652	FTH1	3.90499878269733
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/9	62/9376	16.8028673835125	IRS2	3.86963726150264
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/9	65/9376	16.0273504273504	CGA	3.76831814714604
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/9	69/9376	15.0982286634461	FOS	3.64326592119551
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/9	70/9376	14.8825396825397	IRS2	3.61362475156178
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/9	75/9376	13.8903703703704	CGA	3.47406418623207
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/9	76/9376	13.7076023391813	OLR1	3.44774843967559
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/9	78/9376	13.3561253561254	FOS	3.39657703492916
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/9	78/9376	13.3561253561254	FOS	3.39657703492916
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/9	87/9376	11.9744572158365	FOS	3.18760740766379
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/9	90/9376	11.5753086419753	IRS2	3.12468756461494
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/9	90/9376	11.5753086419753	FOS	3.12468756461494
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/9	91/9376	11.4481074481074	FOS	3.10437376921918
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/9	93/9376	11.2019115890084	FOS	3.06468249283534
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/9	93/9376	11.2019115890084	CGA	3.06468249283534
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/9	95/9376	10.966081871345	FOS	3.0261851772284
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/9	97/9376	10.7399770904926	FOS	2.98882060052968
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/9	99/9376	10.5230078563412	FOS	2.95253187191246
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/9	99/9376	10.5230078563412	FOS	2.95253187191246
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/9	103/9376	10.1143473570658	FOS	2.88297377095514
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/9	105/9376	9.92169312169312	TNFAIP3	2.84960899230825
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/9	105/9376	9.92169312169312	CLEC4E	2.84960899230825
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/9	109/9376	9.55759429153925	FOS	2.7854924994152
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/9	109/9376	9.55759429153925	FOS	2.7854924994152
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/9	109/9376	9.55759429153925	IRS2	2.7854924994152
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/9	115/9376	9.05893719806763	FOS	2.69528306333153
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/9	115/9376	9.05893719806763	DUSP1	2.69528306333153
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/9	115/9376	9.05893719806763	FOS	2.69528306333153
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/9	122/9376	8.53916211293261	IRS2	2.59803431229005
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/9	122/9376	8.53916211293261	FOS	2.59803431229005
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/9	130/9376	8.01367521367521	FOS	2.49601399046791
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/9	133/9376	7.83291562238931	IRS2	2.45998259603897
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/9	133/9376	7.83291562238931	FOS	2.45998259603897
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/9	137/9376	7.60421735604217	FOS	2.41365832052529
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/9	138/9376	7.54911433172303	IRS2	2.40236929957327
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/9	138/9376	7.54911433172303	FOS	2.40236929957327
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/9	139/9376	7.49480415667466	FOS	2.39119294715483
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/9	142/9376	7.33646322378717	FOS	2.358320295426
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/9	148/9376	7.03903903903904	FOS	2.29536383452686
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/9	154/9376	6.76479076479076	FOS	2.2358259029276
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/9	155/9376	6.72114695340502	OLR1	2.22621228023495
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/9	163/9376	6.39127471029312	FOS	2.15224328316596
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/9	166/9376	6.27576974564926	IRS2	2.12577206075443
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/9	169/9376	6.16436554898093	IRS2	2.09994484842741
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/9	181/9376	5.75567833026397	CLEC4E	2.00254611142962
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/9	187/9376	5.57100415923945	TNFAIP3	1.95706354289177
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/9	196/9376	5.31519274376417	FOS	1.8924025592178
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/9	200/9376	5.20888888888889	FOS	1.86492937236651
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/9	205/9376	5.08184281842818	TNFAIP3	1.831603622173
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/9	212/9376	4.91404612159329	DOCK4	1.78672601941657
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/9	214/9376	4.8681204569055	FOS	1.77426451051991
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/9	217/9376	4.80081925243216	FOS	1.75585920004678
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/9	224/9376	4.65079365079365	FOS	1.71419381114851
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/9	227/9376	4.58932941752325	FOS	1.69686021013555
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/9	238/9376	4.37721755368814	FOS	1.63579385503493
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/9	248/9376	4.20071684587814	FOS	1.58340463951815
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/9	268/9376	3.88723051409619	DUSP1	1.48642834310897
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/9	323/9376	3.22531819745442	IRS2	1.26154792370906
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/9	370/9376	2.81561561561562	CGA	1.10449926921677
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/9	388/9376	2.68499427262314	IRS2	1.05072579152491