ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005085 guanyl-nucleotide exchange factor activity 17/443 230/18639 0.0739130434782609 3.10985376386299 3.81155828033681e-05 0.033236788204537 GO:0045296 cadherin binding 19/443 334/18639 0.0568862275449102 2.3934591313986 0.000431189167190985 0.107437650832136 GO:0140328 floppase activity 4/443 16/18639 0.25 10.5186230248307 0.000456567822160825 0.107437650832136 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 24/443 484/18639 0.0495867768595041 2.08633845120609 0.000600885884589882 0.107437650832136 GO:0001216 DNA-binding transcription activator activity 24/443 491/18639 0.0488798370672098 2.0565943185005 0.000734305482225798 0.107437650832136 GO:0034185 apolipoprotein binding 4/443 18/18639 0.222222222222222 9.34988713318285 0.000739249891046808 0.107437650832136 GO:0050660 flavin adenine dinucleotide binding 8/443 86/18639 0.0930232558139535 3.91390624179747 0.00100447773784198 0.125129226771173 GO:0140297 DNA-binding transcription factor binding 23/443 488/18639 0.0471311475409836 1.98301909484513 0.00151787740728367 0.139533639963829 GO:0030695 GTPase regulator activity 23/443 489/18639 0.0470347648261759 1.97896384107244 0.00155855163018356 0.139533639963829 GO:0060589 nucleoside-triphosphatase regulator activity 23/443 490/18639 0.0469387755102041 1.97492513935597 0.00160015642160355 0.139533639963829 GO:0034056 estrogen response element binding 3/443 11/18639 0.272727272727273 11.4748614816335 0.0019086791908465 0.149673943619611 GO:0003995 acyl-CoA dehydrogenase activity 3/443 12/18639 0.25 10.5186230248307 0.00250026547734837 0.149673943619611 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 3/443 12/18639 0.25 10.5186230248307 0.00250026547734837 0.149673943619611 GO:0004709 MAP kinase kinase kinase activity 4/443 25/18639 0.16 6.73191873589165 0.00267977440801418 0.149673943619611 GO:0001786 phosphatidylserine binding 6/443 59/18639 0.101694915254237 4.27876190840571 0.00270930357428709 0.149673943619611 GO:0001727 lipid kinase activity 5/443 41/18639 0.121951219512195 5.13103562186863 0.00274631089210296 0.149673943619611 GO:0052742 phosphatidylinositol kinase activity 4/443 26/18639 0.153846153846154 6.4729987845112 0.00310831125822364 0.159438083363001 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 4/443 27/18639 0.148148148148148 6.23325808878856 0.00358131854534269 0.173494987307713 GO:0003712 transcription coregulator activity 22/443 495/18639 0.0444444444444444 1.86997742663657 0.0038722855792381 0.176150324714048 GO:0005179 hormone activity 9/443 132/18639 0.0681818181818182 2.86871537040837 0.00432147721501834 0.176150324714048 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 17/443 349/18639 0.0487106017191977 2.04947382718764 0.00433238958957465 0.176150324714048 GO:0008237 metallopeptidase activity 11/443 184/18639 0.0597826086956522 2.51532289724212 0.00464018898591797 0.176150324714048 GO:0004222 metalloendopeptidase activity 8/443 110/18639 0.0727272727272727 3.05996306176893 0.00474544414157709 0.176150324714048 GO:0003779 actin binding 20/443 443/18639 0.0451467268623025 1.89952560267823 0.00484817407469857 0.176150324714048 GO:0017124 SH3 domain binding 8/443 115/18639 0.0695652173913043 2.92692118951811 0.00618750642071381 0.215820223954498 GO:0071813 lipoprotein particle binding 4/443 32/18639 0.125 5.25931151241535 0.00668502487838226 0.215901544220346 GO:0071814 protein-lipid complex binding 4/443 32/18639 0.125 5.25931151241535 0.00668502487838226 0.215901544220346 GO:0140416 transcription regulator inhibitor activity 4/443 33/18639 0.121212121212121 5.09993843628155 0.00746695726165956 0.232542383291683 GO:0008525 phosphatidylcholine transporter activity 3/443 18/18639 0.166666666666667 7.01241534988713 0.00834331834811495 0.250874951708836 GO:0017022 myosin binding 6/443 76/18639 0.0789473684210526 3.32167042889391 0.00939467668972625 0.273071935781376 GO:0051015 actin filament binding 11/443 209/18639 0.0526315789473684 2.21444695259594 0.0116089119467144 0.32654745863016 GO:0010314 phosphatidylinositol-5-phosphate binding 3/443 21/18639 0.142857142857143 6.01064172847469 0.0129024530151599 0.340937546339983 GO:0036122 BMP binding 3/443 21/18639 0.142857142857143 6.01064172847469 0.0129024530151599 0.340937546339983 GO:0031625 ubiquitin protein ligase binding 14/443 302/18639 0.0463576158940397 1.95047314367722 0.0136692985467412 0.345219924280211 GO:0098531 ligand-modulated transcription factor activity 5/443 60/18639 0.0833333333333333 3.50620767494357 0.013881214820631 0.345219924280211 GO:0050997 quaternary ammonium group binding 4/443 40/18639 0.1 4.20744920993228 0.0146480931173943 0.345219924280211 GO:0071949 FAD binding 4/443 40/18639 0.1 4.20744920993228 0.0146480931173943 0.345219924280211 GO:0042169 SH2 domain binding 4/443 41/18639 0.0975609756097561 4.10482849749491 0.0159347722768852 0.365661090143261 GO:0004602 glutathione peroxidase activity 3/443 23/18639 0.130434782608696 5.48797723034645 0.0165908703822172 0.370954845469062 GO:0004712 protein serine/threonine/tyrosine kinase activity 4/443 43/18639 0.0930232558139535 3.91390624179747 0.0187155610634181 0.400539843831504 GO:0038024 cargo receptor activity 5/443 65/18639 0.0769230769230769 3.2364993922556 0.0190812583755546 0.400539843831504 GO:0072341 modified amino acid binding 6/443 91/18639 0.0659340659340659 2.77414233621909 0.0213501746655806 0.400539843831504 GO:1990782 protein tyrosine kinase binding 7/443 117/18639 0.0598290598290598 2.51727730508769 0.0217274211772131 0.400539843831504 GO:0140303 intramembrane lipid transporter activity 4/443 45/18639 0.0888888888888889 3.73995485327314 0.0217791744034811 0.400539843831504 GO:0005345 purine nucleobase transmembrane transporter activity 2/443 10/18639 0.2 8.41489841986456 0.0223540768623807 0.400539843831504 GO:0005522 profilin binding 2/443 10/18639 0.2 8.41489841986456 0.0223540768623807 0.400539843831504 GO:0044389 ubiquitin-like protein ligase binding 14/443 322/18639 0.0434782608695652 1.82932574344882 0.0224422480840328 0.400539843831504 GO:0043548 phosphatidylinositol 3-kinase binding 3/443 26/18639 0.115384615384615 4.8547490883834 0.023117594519921 0.400539843831504 GO:0030291 protein serine/threonine kinase inhibitor activity 4/443 46/18639 0.0869565217391304 3.65865148689763 0.0234190786768179 0.400539843831504 GO:0003714 transcription corepressor activity 10/443 204/18639 0.0490196078431373 2.06247510290798 0.0243833757430469 0.400539843831504 GO:0097110 scaffold protein binding 5/443 70/18639 0.0714285714285714 3.00532086423734 0.0254209755168288 0.400539843831504 GO:0008432 JUN kinase binding 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.400539843831504 GO:0015205 nucleobase transmembrane transporter activity 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.400539843831504 GO:0032050 clathrin heavy chain binding 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.400539843831504 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.400539843831504 GO:0042608 T cell receptor binding 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.400539843831504 GO:0048185 activin binding 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.400539843831504 GO:0180030 inositol phosphate kinase activity 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.400539843831504 GO:0019842 vitamin binding 8/443 150/18639 0.0533333333333333 2.24397291196388 0.0271007463142875 0.400539843831504 GO:0051959 dynein light intermediate chain binding 3/443 28/18639 0.107142857142857 4.50798129635601 0.0281346764563712 0.408117561694443 GO:0042626 ATPase-coupled transmembrane transporter activity 6/443 98/18639 0.0612244897959184 2.57598931220344 0.0294198070044997 0.408117561694443 GO:0043236 laminin binding 3/443 29/18639 0.103448275862069 4.35253366544719 0.0308422423638647 0.408117561694443 GO:0048029 monosaccharide binding 5/443 74/18639 0.0675675675675676 2.84287108779208 0.0313618646089348 0.408117561694443 GO:0004859 phospholipase inhibitor activity 2/443 12/18639 0.166666666666667 7.01241534988713 0.0317769451851295 0.408117561694443 GO:0015132 prostaglandin transmembrane transporter activity 2/443 12/18639 0.166666666666667 7.01241534988713 0.0317769451851295 0.408117561694443 GO:0015166 polyol transmembrane transporter activity 2/443 12/18639 0.166666666666667 7.01241534988713 0.0317769451851295 0.408117561694443 GO:0017166 vinculin binding 2/443 12/18639 0.166666666666667 7.01241534988713 0.0317769451851295 0.408117561694443 GO:0044183 protein folding chaperone 5/443 75/18639 0.0666666666666667 2.80496613995485 0.0329716436151647 0.408117561694443 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/443 30/18639 0.1 4.20744920993228 0.0336816112886474 0.408117561694443 GO:0016769 transferase activity, transferring nitrogenous groups 3/443 30/18639 0.1 4.20744920993228 0.0336816112886474 0.408117561694443 GO:0070273 phosphatidylinositol-4-phosphate binding 3/443 31/18639 0.0967741935483871 4.07172504186995 0.0366518615128694 0.408117561694443 GO:0008035 high-density lipoprotein particle binding 2/443 13/18639 0.153846153846154 6.4729987845112 0.0369739534103911 0.408117561694443 GO:0019855 calcium channel inhibitor activity 2/443 13/18639 0.153846153846154 6.4729987845112 0.0369739534103911 0.408117561694443 GO:0043560 insulin receptor substrate binding 2/443 13/18639 0.153846153846154 6.4729987845112 0.0369739534103911 0.408117561694443 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/443 13/18639 0.153846153846154 6.4729987845112 0.0369739534103911 0.408117561694443 GO:0045159 myosin II binding 2/443 13/18639 0.153846153846154 6.4729987845112 0.0369739534103911 0.408117561694443 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/443 13/18639 0.153846153846154 6.4729987845112 0.0369739534103911 0.408117561694443 GO:0071714 icosanoid transmembrane transporter activity 2/443 13/18639 0.153846153846154 6.4729987845112 0.0369739534103911 0.408117561694443 GO:0140333 glycerophospholipid flippase activity 2/443 13/18639 0.153846153846154 6.4729987845112 0.0369739534103911 0.408117561694443 GO:0051059 NF-kappaB binding 3/443 32/18639 0.09375 3.94448363431151 0.0397518790957473 0.433295482143646 GO:0005545 1-phosphatidylinositol binding 2/443 14/18639 0.142857142857143 6.01064172847469 0.0424707443186777 0.434366793263992 GO:0044548 S100 protein binding 2/443 14/18639 0.142857142857143 6.01064172847469 0.0424707443186777 0.434366793263992 GO:1901612 cardiolipin binding 2/443 14/18639 0.142857142857143 6.01064172847469 0.0424707443186777 0.434366793263992 GO:0003713 transcription coactivator activity 11/443 256/18639 0.04296875 1.80788833239278 0.0430118246834104 0.434366793263992 GO:0030170 pyridoxal phosphate binding 4/443 56/18639 0.0714285714285714 3.00532086423734 0.0439052871047957 0.434366793263992 GO:0170055 lipid transmembrane transporter activity 4/443 56/18639 0.0714285714285714 3.00532086423734 0.0439052871047957 0.434366793263992 GO:0004601 peroxidase activity 4/443 57/18639 0.0701754385964912 2.95259593679458 0.046368203840794 0.434366793263992 GO:0070279 vitamin B6 binding 4/443 57/18639 0.0701754385964912 2.95259593679458 0.046368203840794 0.434366793263992 GO:0005201 extracellular matrix structural constituent 8/443 168/18639 0.0476190476190476 2.0035472428249 0.0477882888569577 0.434366793263992 GO:0015250 water channel activity 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.434366793263992 GO:0016846 carbon-sulfur lyase activity 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.434366793263992 GO:0140776 protein-containing complex destabilizing activity 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.434366793263992 GO:0141050 histone H3K deacetylase activity 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.434366793263992 GO:0141051 histone H4K deacetylase activity 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.434366793263992 GO:0004860 protein kinase inhibitor activity 5/443 84/18639 0.0595238095238095 2.50443405353112 0.0497667729319375 0.434366793263992 GO:0180051 translation factor activity 5/443 84/18639 0.0595238095238095 2.50443405353112 0.0497667729319375 0.434366793263992 GO:0106310 protein serine kinase activity 14/443 361/18639 0.038781163434903 1.63169775454437 0.0507194146468996 0.434366793263992 GO:0005543 phospholipid binding 18/443 497/18639 0.0362173038229376 1.52382466355696 0.0514395711509628 0.434366793263992 GO:0004879 nuclear receptor activity 4/443 59/18639 0.0677966101694915 2.85250793893714 0.0515200684733423 0.434366793263992 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/443 59/18639 0.0677966101694915 2.85250793893714 0.0515200684733423 0.434366793263992 GO:0004033 aldo-keto reductase (NADPH) activity 3/443 36/18639 0.0833333333333333 3.50620767494357 0.0534213500945971 0.434366793263992 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/443 86/18639 0.0581395348837209 2.44619140112342 0.0540710201922361 0.434366793263992 GO:0000062 fatty-acyl-CoA binding 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.434366793263992 GO:0004708 MAP kinase kinase activity 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.434366793263992 GO:0005159 insulin-like growth factor receptor binding 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.434366793263992 GO:0015562 efflux transmembrane transporter activity 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.434366793263992 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.434366793263992 GO:0055102 lipase inhibitor activity 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.434366793263992 GO:0140327 flippase activity 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.434366793263992 GO:0043394 proteoglycan binding 3/443 37/18639 0.0810810810810811 3.4114453053505 0.0571476721975759 0.451187726211626 GO:0008514 organic anion transmembrane transporter activity 11/443 269/18639 0.0408921933085502 1.72051826428458 0.0574333000108836 0.451187726211626 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/443 17/18639 0.117647058823529 4.94994024697915 0.0605918325650296 0.454574563248538 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/443 17/18639 0.117647058823529 4.94994024697915 0.0605918325650296 0.454574563248538 GO:0030169 low-density lipoprotein particle binding 2/443 17/18639 0.117647058823529 4.94994024697915 0.0605918325650296 0.454574563248538 GO:0038191 neuropilin binding 2/443 17/18639 0.117647058823529 4.94994024697915 0.0605918325650296 0.454574563248538 GO:1901567 fatty acid derivative binding 2/443 17/18639 0.117647058823529 4.94994024697915 0.0605918325650296 0.454574563248538 GO:0004175 endopeptidase activity 15/443 405/18639 0.037037037037037 1.55831452219714 0.0609922292432098 0.454574563248538 GO:0019210 kinase inhibitor activity 5/443 90/18639 0.0555555555555556 2.33747178329571 0.063306988560732 0.466666050152757 GO:0008017 microtubule binding 11/443 276/18639 0.0398550724637681 1.67688193149475 0.0663893987134621 0.466666050152757 GO:0000400 four-way junction DNA binding 2/443 18/18639 0.111111111111111 4.67494356659142 0.0671228968421439 0.466666050152757 GO:0003746 translation elongation factor activity 2/443 18/18639 0.111111111111111 4.67494356659142 0.0671228968421439 0.466666050152757 GO:0004706 JUN kinase kinase kinase activity 2/443 18/18639 0.111111111111111 4.67494356659142 0.0671228968421439 0.466666050152757 GO:0005372 water transmembrane transporter activity 2/443 18/18639 0.111111111111111 4.67494356659142 0.0671228968421439 0.466666050152757 GO:0030228 lipoprotein particle receptor activity 2/443 18/18639 0.111111111111111 4.67494356659142 0.0671228968421439 0.466666050152757 GO:1901611 phosphatidylglycerol binding 2/443 18/18639 0.111111111111111 4.67494356659142 0.0671228968421439 0.466666050152757 GO:0015036 disulfide oxidoreductase activity 3/443 40/18639 0.075 3.15558690744921 0.0690366060432404 0.466666050152757 GO:0015144 carbohydrate transmembrane transporter activity 3/443 40/18639 0.075 3.15558690744921 0.0690366060432404 0.466666050152757 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/443 40/18639 0.075 3.15558690744921 0.0690366060432404 0.466666050152757 GO:0030331 nuclear estrogen receptor binding 3/443 40/18639 0.075 3.15558690744921 0.0690366060432404 0.466666050152757 GO:0008235 metalloexopeptidase activity 4/443 66/18639 0.0606060606060606 2.54996921814078 0.0718914632990451 0.470207656551692 GO:0004857 enzyme inhibitor activity 15/443 416/18639 0.0360576923076923 1.51710909011981 0.0729788670594033 0.470207656551692 GO:0005229 intracellularly calcium-gated chloride channel activity 2/443 19/18639 0.105263157894737 4.42889390519187 0.0738743680591535 0.470207656551692 GO:0008381 mechanosensitive monoatomic ion channel activity 2/443 19/18639 0.105263157894737 4.42889390519187 0.0738743680591535 0.470207656551692 GO:0043395 heparan sulfate proteoglycan binding 2/443 19/18639 0.105263157894737 4.42889390519187 0.0738743680591535 0.470207656551692 GO:0046624 sphingolipid transporter activity 2/443 19/18639 0.105263157894737 4.42889390519187 0.0738743680591535 0.470207656551692 GO:0120227 acyl-CoA binding 2/443 19/18639 0.105263157894737 4.42889390519187 0.0738743680591535 0.470207656551692 GO:0141147 intracellularly calcium-gated channel activity 2/443 19/18639 0.105263157894737 4.42889390519187 0.0738743680591535 0.470207656551692 GO:0008307 structural constituent of muscle 3/443 42/18639 0.0714285714285714 3.00532086423734 0.0775318248567418 0.482778226360096 GO:0016859 cis-trans isomerase activity 3/443 42/18639 0.0714285714285714 3.00532086423734 0.0775318248567418 0.482778226360096 GO:0005548 phospholipid transporter activity 4/443 68/18639 0.0588235294117647 2.47497012348958 0.0783642667765942 0.482778226360096 GO:0001614 purinergic nucleotide receptor activity 2/443 20/18639 0.1 4.20744920993228 0.0808321342300161 0.482778226360096 GO:0016502 nucleotide receptor activity 2/443 20/18639 0.1 4.20744920993228 0.0808321342300161 0.482778226360096 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/443 20/18639 0.1 4.20744920993228 0.0808321342300161 0.482778226360096 GO:0031418 L-ascorbic acid binding 2/443 20/18639 0.1 4.20744920993228 0.0808321342300161 0.482778226360096 GO:0043024 ribosomal small subunit binding 2/443 20/18639 0.1 4.20744920993228 0.0808321342300161 0.482778226360096 GO:0052745 inositol phosphate phosphatase activity 2/443 20/18639 0.1 4.20744920993228 0.0808321342300161 0.482778226360096 GO:0008375 acetylglucosaminyltransferase activity 3/443 43/18639 0.0697674418604651 2.9354296813481 0.081943044641241 0.483751399318955 GO:0019207 kinase regulator activity 11/443 287/18639 0.0383275261324042 1.61261119544443 0.0822052511878622 0.483751399318955 GO:0042826 histone deacetylase binding 6/443 127/18639 0.047244094488189 1.98777128028297 0.0826593560762892 0.483751399318955 GO:0031490 chromatin DNA binding 6/443 128/18639 0.046875 1.97224181715576 0.0850865993027023 0.494636763946376 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/443 21/18639 0.0952380952380952 4.00709448564979 0.0879826269894745 0.50474243904488 GO:0051428 peptide hormone receptor binding 2/443 21/18639 0.0952380952380952 4.00709448564979 0.0879826269894745 0.50474243904488 GO:0004674 protein serine/threonine kinase activity 15/443 433/18639 0.0346420323325635 1.45754591568093 0.0943898550956447 0.529569956782697 GO:0004407 histone deacetylase activity 2/443 22/18639 0.0909090909090909 3.82495382721116 0.0953128038201283 0.529569956782697 GO:0008970 phospholipase A1 activity 2/443 22/18639 0.0909090909090909 3.82495382721116 0.0953128038201283 0.529569956782697 GO:0033558 protein lysine deacetylase activity 2/443 22/18639 0.0909090909090909 3.82495382721116 0.0953128038201283 0.529569956782697 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/443 46/18639 0.0652173913043478 2.74398861517323 0.0958005702304751 0.529569956782697 GO:0008238 exopeptidase activity 5/443 102/18639 0.0490196078431373 2.06247510290798 0.0959541894170483 0.529569956782697 GO:0035064 methylated histone binding 4/443 74/18639 0.0540540540540541 2.27429687023366 0.0994382820364007 0.544966872847366 GO:0051087 protein-folding chaperone binding 6/443 134/18639 0.0447761194029851 1.88393248205923 0.100463568204717 0.544966872847366 GO:0140359 ABC-type transporter activity 3/443 47/18639 0.0638297872340425 2.68560587868018 0.100618883633516 0.544966872847366 GO:0015399 primary active transmembrane transporter activity 7/443 166/18639 0.0421686746987952 1.77422557045337 0.101612268924521 0.54664898823168 GO:0070577 lysine-acetylated histone binding 2/443 23/18639 0.0869565217391304 3.65865148689763 0.102810130814215 0.54664898823168 GO:0099186 structural constituent of postsynapse 2/443 23/18639 0.0869565217391304 3.65865148689763 0.102810130814215 0.54664898823168 GO:0019838 growth factor binding 6/443 136/18639 0.0441176470588235 1.85622759261718 0.105894219537677 0.558350377157026 GO:0098631 cell adhesion mediator activity 4/443 76/18639 0.0526315789473684 2.21444695259594 0.106991264049933 0.558350377157026 GO:0140034 methylation-dependent protein binding 4/443 76/18639 0.0526315789473684 2.21444695259594 0.106991264049933 0.558350377157026 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/443 268/18639 0.0373134328358209 1.56994373504936 0.107572091011904 0.558350377157026 GO:0016922 nuclear receptor binding 6/443 137/18639 0.0437956204379562 1.84267848610173 0.108665652742774 0.560019520422087 GO:0030215 semaphorin receptor binding 2/443 24/18639 0.0833333333333333 3.50620767494357 0.110462565954815 0.560019520422087 GO:0070300 phosphatidic acid binding 2/443 24/18639 0.0833333333333333 3.50620767494357 0.110462565954815 0.560019520422087 GO:0140033 acetylation-dependent protein binding 2/443 24/18639 0.0833333333333333 3.50620767494357 0.110462565954815 0.560019520422087 GO:0019888 protein phosphatase regulator activity 5/443 107/18639 0.0467289719626168 1.9660977616506 0.111657184771336 0.562803844627775 GO:0003707 nuclear steroid receptor activity 2/443 25/18639 0.08 3.36595936794582 0.118258542901613 0.579333985450596 GO:0008483 transaminase activity 2/443 25/18639 0.08 3.36595936794582 0.118258542901613 0.579333985450596 GO:0015662 P-type ion transporter activity 2/443 25/18639 0.08 3.36595936794582 0.118258542901613 0.579333985450596 GO:0120020 cholesterol transfer activity 2/443 25/18639 0.08 3.36595936794582 0.118258542901613 0.579333985450596 GO:0140358 P-type transmembrane transporter activity 2/443 25/18639 0.08 3.36595936794582 0.118258542901613 0.579333985450596 GO:1901681 sulfur compound binding 10/443 275/18639 0.0363636363636364 1.52998153088447 0.121536935043588 0.580242122191007 GO:0048306 calcium-dependent protein binding 4/443 80/18639 0.05 2.10372460496614 0.122841376699326 0.580242122191007 GO:0016887 ATP hydrolysis activity 14/443 417/18639 0.0335731414868106 1.41257287623626 0.123995988704519 0.580242122191007 GO:1902936 phosphatidylinositol bisphosphate binding 5/443 111/18639 0.045045045045045 1.89524739186139 0.125053870568789 0.580242122191007 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/443 52/18639 0.0576923076923077 2.4273745441917 0.126080463381399 0.580242122191007 GO:0030159 signaling receptor complex adaptor activity 3/443 52/18639 0.0576923076923077 2.4273745441917 0.126080463381399 0.580242122191007 GO:0008198 ferrous iron binding 2/443 26/18639 0.0769230769230769 3.2364993922556 0.126186955266753 0.580242122191007 GO:0050750 low-density lipoprotein particle receptor binding 2/443 26/18639 0.0769230769230769 3.2364993922556 0.126186955266753 0.580242122191007 GO:0070006 metalloaminopeptidase activity 2/443 26/18639 0.0769230769230769 3.2364993922556 0.126186955266753 0.580242122191007 GO:0070412 R-SMAD binding 2/443 26/18639 0.0769230769230769 3.2364993922556 0.126186955266753 0.580242122191007 GO:0001618 virus receptor activity 4/443 81/18639 0.0493827160493827 2.07775269626285 0.126952497079771 0.580242122191007 GO:0030971 receptor tyrosine kinase binding 4/443 81/18639 0.0493827160493827 2.07775269626285 0.126952497079771 0.580242122191007 GO:0001217 DNA-binding transcription repressor activity 10/443 278/18639 0.0359712230215827 1.51347093882456 0.127814550834255 0.580242122191007 GO:0015631 tubulin binding 13/443 385/18639 0.0337662337662338 1.42069713582129 0.13053035258567 0.580242122191007 GO:0140272 exogenous protein binding 4/443 82/18639 0.0487804878048781 2.05241424874745 0.131120746175493 0.580242122191007 GO:0005246 calcium channel regulator activity 3/443 53/18639 0.0566037735849057 2.38157502448997 0.131427091242454 0.580242122191007 GO:0005544 calcium-dependent phospholipid binding 3/443 53/18639 0.0566037735849057 2.38157502448997 0.131427091242454 0.580242122191007 GO:0016860 intramolecular oxidoreductase activity 3/443 53/18639 0.0566037735849057 2.38157502448997 0.131427091242454 0.580242122191007 GO:0005319 lipid transporter activity 7/443 178/18639 0.0393258426966292 1.65461485783854 0.132581530937117 0.580242122191007 GO:0004364 glutathione transferase activity 2/443 27/18639 0.0740740740740741 3.11662904439428 0.134237141366754 0.580242122191007 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/443 27/18639 0.0740740740740741 3.11662904439428 0.134237141366754 0.580242122191007 GO:0001540 amyloid-beta binding 4/443 83/18639 0.0481927710843374 2.02768636623242 0.135344931012452 0.580242122191007 GO:0008135 translation factor activity, RNA binding 4/443 83/18639 0.0481927710843374 2.02768636623242 0.135344931012452 0.580242122191007 GO:0030165 PDZ domain binding 4/443 83/18639 0.0481927710843374 2.02768636623242 0.135344931012452 0.580242122191007 GO:0033218 amide binding 9/443 247/18639 0.0364372469635627 1.53307865948949 0.13572904854089 0.580242122191007 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/443 54/18639 0.0555555555555556 2.33747178329571 0.136851852432972 0.580242122191007 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/443 54/18639 0.0555555555555556 2.33747178329571 0.136851852432972 0.580242122191007 GO:0016853 isomerase activity 7/443 180/18639 0.0388888888888889 1.636230248307 0.138154531289683 0.580242122191007 GO:0031267 small GTPase binding 10/443 283/18639 0.0353356890459364 1.48673116958738 0.138659757766812 0.580242122191007 GO:0001221 transcription coregulator binding 5/443 115/18639 0.0434782608695652 1.82932574344882 0.13915319520558 0.580242122191007 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/443 181/18639 0.0386740331491713 1.62719030218375 0.140983374063625 0.580242122191007 GO:0098632 cell-cell adhesion mediator activity 3/443 55/18639 0.0545454545454545 2.2949722963267 0.142351887363236 0.580242122191007 GO:0140313 molecular sequestering activity 3/443 55/18639 0.0545454545454545 2.2949722963267 0.142351887363236 0.580242122191007 GO:0045499 chemorepellent activity 2/443 28/18639 0.0714285714285714 3.00532086423734 0.142398869436784 0.580242122191007 GO:0046966 nuclear thyroid hormone receptor binding 2/443 28/18639 0.0714285714285714 3.00532086423734 0.142398869436784 0.580242122191007 GO:0097718 disordered domain specific binding 2/443 28/18639 0.0714285714285714 3.00532086423734 0.142398869436784 0.580242122191007 GO:0019208 phosphatase regulator activity 5/443 117/18639 0.0427350427350427 1.79805521791978 0.146453872348745 0.593989659014444 GO:0016209 antioxidant activity 4/443 86/18639 0.0465116279069767 1.95695312089873 0.148340883863137 0.598857642262294 GO:0004181 metallocarboxypeptidase activity 2/443 29/18639 0.0689655172413793 2.90168911029812 0.150662323294037 0.602649293176148 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/443 29/18639 0.0689655172413793 2.90168911029812 0.150662323294037 0.602649293176148 GO:0019887 protein kinase regulator activity 9/443 255/18639 0.0352941176470588 1.48498207409375 0.15519141555355 0.617931115811397 GO:0003774 cytoskeletal motor activity 6/443 153/18639 0.0392156862745098 1.64998008232638 0.157820870340812 0.62128028261165 GO:0001968 fibronectin binding 2/443 30/18639 0.0666666666666667 2.80496613995485 0.159018088437279 0.62128028261165 GO:0031210 phosphatidylcholine binding 2/443 30/18639 0.0666666666666667 2.80496613995485 0.159018088437279 0.62128028261165 GO:0098918 structural constituent of synapse 2/443 30/18639 0.0666666666666667 2.80496613995485 0.159018088437279 0.62128028261165 GO:0051082 unfolded protein binding 5/443 121/18639 0.0413223140495868 1.73861537600507 0.161530329770435 0.62128028261165 GO:0046943 carboxylic acid transmembrane transporter activity 7/443 188/18639 0.0372340425531915 1.5666034292301 0.161550096235875 0.62128028261165 GO:0005342 organic acid transmembrane transporter activity 7/443 189/18639 0.037037037037037 1.55831452219714 0.164593945467428 0.62128028261165 GO:0005184 neuropeptide hormone activity 2/443 31/18639 0.0645161290322581 2.71448336124663 0.167457138569997 0.62128028261165 GO:0047499 calcium-independent phospholipase A2 activity 2/443 31/18639 0.0645161290322581 2.71448336124663 0.167457138569997 0.62128028261165 GO:0070325 lipoprotein particle receptor binding 2/443 31/18639 0.0645161290322581 2.71448336124663 0.167457138569997 0.62128028261165 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/443 60/18639 0.05 2.10372460496614 0.170881286191561 0.62128028261165 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/443 91/18639 0.043956043956044 1.84942822414606 0.171003128941451 0.62128028261165 GO:0015106 bicarbonate transmembrane transporter activity 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.62128028261165 GO:0042910 xenobiotic transmembrane transporter activity 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.62128028261165 GO:0047498 calcium-dependent phospholipase A2 activity 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.62128028261165 GO:0120015 sterol transfer activity 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.62128028261165 GO:0160041 neuropeptide activity 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.62128028261165 GO:0015026 coreceptor activity 3/443 61/18639 0.0491803278688525 2.06923731636014 0.176773162493238 0.62128028261165 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/443 61/18639 0.0491803278688525 2.06923731636014 0.176773162493238 0.62128028261165 GO:0019905 syntaxin binding 3/443 61/18639 0.0491803278688525 2.06923731636014 0.176773162493238 0.62128028261165 GO:0051219 phosphoprotein binding 4/443 93/18639 0.043010752688172 1.80965557416442 0.180388614174925 0.62128028261165 GO:0004866 endopeptidase inhibitor activity 6/443 161/18639 0.0372670807453416 1.5679934943847 0.18548171845238 0.62128028261165 GO:0005178 integrin binding 6/443 161/18639 0.0372670807453416 1.5679934943847 0.18548171845238 0.62128028261165 GO:0015035 protein-disulfide reductase activity 2/443 34/18639 0.0588235294117647 2.47497012348958 0.193189287421308 0.62128028261165 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/443 34/18639 0.0588235294117647 2.47497012348958 0.193189287421308 0.62128028261165 GO:0051427 hormone receptor binding 2/443 34/18639 0.0588235294117647 2.47497012348958 0.193189287421308 0.62128028261165 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/443 34/18639 0.0588235294117647 2.47497012348958 0.193189287421308 0.62128028261165 GO:0016298 lipase activity 5/443 130/18639 0.0384615384615385 1.6182496961278 0.197555903108851 0.62128028261165 GO:0031072 heat shock protein binding 5/443 131/18639 0.0381679389312977 1.60589664501232 0.201720745244289 0.62128028261165 GO:0004623 phospholipase A2 activity 2/443 35/18639 0.0571428571428571 2.40425669138987 0.20187852965987 0.62128028261165 GO:0016409 palmitoyltransferase activity 2/443 36/18639 0.0555555555555556 2.33747178329571 0.210611304928415 0.62128028261165 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/443 36/18639 0.0555555555555556 2.33747178329571 0.210611304928415 0.62128028261165 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/443 36/18639 0.0555555555555556 2.33747178329571 0.210611304928415 0.62128028261165 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/443 36/18639 0.0555555555555556 2.33747178329571 0.210611304928415 0.62128028261165 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/443 67/18639 0.0447761194029851 1.88393248205923 0.213192970782207 0.62128028261165 GO:0050840 extracellular matrix binding 3/443 67/18639 0.0447761194029851 1.88393248205923 0.213192970782207 0.62128028261165 GO:0001094 TFIID-class transcription factor complex binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0004090 carbonyl reductase (NADPH) activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0005337 nucleoside transmembrane transporter activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0005528 FK506 binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0008140 cAMP response element binding protein binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0016427 tRNA (cytidine) methyltransferase activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0019531 oxalate transmembrane transporter activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0031434 mitogen-activated protein kinase kinase binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0031720 haptoglobin binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0031996 thioesterase binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0042975 peroxisome proliferator activated receptor binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0045322 unmethylated CpG binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0140135 mechanosensitive monoatomic cation channel activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:1990763 arrestin family protein binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.62128028261165 GO:0030414 peptidase inhibitor activity 6/443 169/18639 0.0355029585798817 1.49376895027182 0.214881140792869 0.62128028261165 GO:0051020 GTPase binding 10/443 315/18639 0.0317460317460317 1.33569816188326 0.218469640011882 0.62128028261165 GO:0019213 deacetylase activity 2/443 37/18639 0.0540540540540541 2.27429687023366 0.219380655370177 0.62128028261165 GO:0030280 structural constituent of skin epidermis 2/443 37/18639 0.0540540540540541 2.27429687023366 0.219380655370177 0.62128028261165 GO:1990841 promoter-specific chromatin binding 3/443 68/18639 0.0441176470588235 1.85622759261718 0.219415834044005 0.62128028261165 GO:0002020 protease binding 5/443 136/18639 0.0367647058823529 1.54685632718099 0.222971453770318 0.62128028261165 GO:0015171 amino acid transmembrane transporter activity 4/443 102/18639 0.0392156862745098 1.64998008232638 0.224539171732237 0.62128028261165 GO:0000146 microfilament motor activity 2/443 38/18639 0.0526315789473684 2.21444695259594 0.228179927871932 0.62128028261165 GO:0140030 modification-dependent protein binding 6/443 173/18639 0.0346820809248555 1.45923093986091 0.230149138556676 0.62128028261165 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/443 70/18639 0.0428571428571429 1.80319251854241 0.231969003642288 0.62128028261165 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0002162 dystroglycan binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0005114 type II transforming growth factor beta receptor binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0005536 D-glucose binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0008046 axon guidance receptor activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0008271 secondary active sulfate transmembrane transporter activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0010854 adenylate cyclase regulator activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0015217 ADP transmembrane transporter activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0019206 nucleoside kinase activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0032794 GTPase activating protein binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0034713 type I transforming growth factor beta receptor binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0043522 leucine zipper domain binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0050998 nitric-oxide synthase binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0070697 activin receptor binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0140537 transcription regulator activator activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.62128028261165 GO:0042393 histone binding 8/443 247/18639 0.0323886639676113 1.36273658621288 0.235505632534718 0.62128028261165 GO:0000217 DNA secondary structure binding 2/443 39/18639 0.0512820512820513 2.15766626150373 0.237002763563723 0.62128028261165 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/443 39/18639 0.0512820512820513 2.15766626150373 0.237002763563723 0.62128028261165 GO:0042277 peptide binding 8/443 249/18639 0.0321285140562249 1.35179091082162 0.242015360470109 0.62128028261165 GO:0000149 SNARE binding 4/443 106/18639 0.0377358490566038 1.58771668299331 0.244993737718618 0.62128028261165 GO:0004497 monooxygenase activity 4/443 106/18639 0.0377358490566038 1.58771668299331 0.244993737718618 0.62128028261165 GO:0004177 aminopeptidase activity 2/443 40/18639 0.05 2.10372460496614 0.245843087643748 0.62128028261165 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/443 40/18639 0.05 2.10372460496614 0.245843087643748 0.62128028261165 GO:0061791 GTPase motor activity 2/443 40/18639 0.05 2.10372460496614 0.245843087643748 0.62128028261165 GO:0071855 neuropeptide receptor binding 2/443 40/18639 0.05 2.10372460496614 0.245843087643748 0.62128028261165 GO:0140662 ATP-dependent protein folding chaperone 2/443 40/18639 0.05 2.10372460496614 0.245843087643748 0.62128028261165 GO:1990606 membrane scission GTPase motor activity 2/443 40/18639 0.05 2.10372460496614 0.245843087643748 0.62128028261165 GO:0020037 heme binding 5/443 142/18639 0.0352112676056338 1.48149620068038 0.249303190646797 0.62128028261165 GO:0004032 aldose reductase (NADPH) activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0005025 transforming growth factor beta receptor activity, type I 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0005026 transforming growth factor beta receptor activity, type II 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0005049 nuclear export signal receptor activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0005165 neurotrophin receptor binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0005247 voltage-gated chloride channel activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0005527 macrolide binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0008603 cAMP-dependent protein kinase regulator activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0010853 cyclase activator activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0016361 activin receptor activity, type I 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0016362 activin receptor activity, type II 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0016840 carbon-nitrogen lyase activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0017002 activin receptor activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0031543 peptidyl-proline dioxygenase activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0035259 nuclear glucocorticoid receptor binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0070679 inositol 1,4,5 trisphosphate binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0140900 chloride:bicarbonate antiporter activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.62128028261165 GO:0017080 sodium channel regulator activity 2/443 41/18639 0.0487804878048781 2.05241424874745 0.254695099518945 0.623468645028066 GO:0005496 steroid binding 4/443 108/18639 0.037037037037037 1.55831452219714 0.255373142104614 0.623468645028066 GO:0004620 phospholipase activity 4/443 109/18639 0.036697247706422 1.54401805869074 0.260596296931214 0.623468645028066 GO:0031492 nucleosomal DNA binding 2/443 42/18639 0.0476190476190476 2.0035472428249 0.263553263252055 0.623468645028066 GO:0046982 protein heterodimerization activity 11/443 369/18639 0.029810298102981 1.25425315201233 0.26394592004441 0.623468645028066 GO:0003924 GTPase activity 10/443 331/18639 0.0302114803625378 1.27113269182244 0.264058141538916 0.623468645028066 GO:0004465 lipoprotein lipase activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0008253 5'-nucleotidase activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0031432 titin binding 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0046975 histone H3K36 methyltransferase activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0070123 transforming growth factor beta receptor activity, type III 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0071837 HMG box domain binding 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0089720 caspase binding 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0140666 annealing activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.623468645028066 GO:0008200 ion channel inhibitor activity 2/443 43/18639 0.0465116279069767 1.95695312089873 0.272412298306241 0.623468645028066 GO:0061135 endopeptidase regulator activity 6/443 184/18639 0.0326086956521739 1.37199430758661 0.273740209999087 0.623468645028066 GO:0005200 structural constituent of cytoskeleton 4/443 112/18639 0.0357142857142857 1.50266043211867 0.276384129248304 0.623468645028066 GO:1901981 phosphatidylinositol phosphate binding 6/443 185/18639 0.0324324324324324 1.3645781221402 0.277801621784009 0.623468645028066 GO:0001046 core promoter sequence-specific DNA binding 2/443 44/18639 0.0454545454545455 1.91247691360558 0.281267170578537 0.623468645028066 GO:0016248 channel inhibitor activity 2/443 44/18639 0.0454545454545455 1.91247691360558 0.281267170578537 0.623468645028066 GO:0019199 transmembrane receptor protein kinase activity 3/443 78/18639 0.0384615384615385 1.6182496961278 0.283251897107977 0.623468645028066 GO:0004065 arylsulfatase activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0004705 JUN kinase activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0005344 oxygen carrier activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0005347 ATP transmembrane transporter activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0008174 mRNA methyltransferase activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0008191 metalloendopeptidase inhibitor activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0008559 ABC-type xenobiotic transporter activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0019992 diacylglycerol binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0032036 myosin heavy chain binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0034236 protein kinase A catalytic subunit binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0042043 neurexin family protein binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0043176 amine binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0046030 inositol trisphosphate phosphatase activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0061665 SUMO ligase activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0071933 Arp2/3 complex binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0098821 BMP receptor activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:1901474 azole transmembrane transporter activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:1990825 sequence-specific mRNA binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.623468645028066 GO:0046332 SMAD binding 3/443 79/18639 0.0379746835443038 1.59776552275909 0.289743871069566 0.623468645028066 GO:0141110 transporter inhibitor activity 2/443 45/18639 0.0444444444444444 1.86997742663657 0.290113083713695 0.623468645028066 GO:0022804 active transmembrane transporter activity 13/443 457/18639 0.0284463894967177 1.19686739013391 0.293188997398324 0.623468645028066 GO:0046906 tetrapyrrole binding 5/443 152/18639 0.0328947368421053 1.38402934537246 0.294745203021893 0.623468645028066 GO:0009055 electron transfer activity 4/443 116/18639 0.0344827586206897 1.45084455514906 0.297663672603945 0.623468645028066 GO:0004180 carboxypeptidase activity 2/443 46/18639 0.0434782608695652 1.82932574344882 0.298945470690206 0.623468645028066 GO:0030276 clathrin binding 2/443 46/18639 0.0434782608695652 1.82932574344882 0.298945470690206 0.623468645028066 GO:0004467 long-chain fatty acid-CoA ligase activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0004559 alpha-mannosidase activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0005041 low-density lipoprotein particle receptor activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0005523 tropomyosin binding 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0008252 nucleotidase activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0015116 sulfate transmembrane transporter activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0015929 hexosaminidase activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0017081 chloride channel regulator activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0031005 filamin binding 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0031386 protein tag activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0047372 monoacylglycerol lipase activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0050700 CARD domain binding 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0140161 monocarboxylate:sodium symporter activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0141047 molecular tag activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.623468645028066 GO:0005506 iron ion binding 5/443 154/18639 0.0324675324675325 1.3660549382897 0.304008485512856 0.623468645028066 GO:0001784 phosphotyrosine residue binding 2/443 47/18639 0.0425531914893617 1.79040391912012 0.307759985670503 0.623468645028066 GO:0043495 protein-membrane adaptor activity 2/443 47/18639 0.0425531914893617 1.79040391912012 0.307759985670503 0.623468645028066 GO:0099095 ligand-gated monoatomic anion channel activity 2/443 47/18639 0.0425531914893617 1.79040391912012 0.307759985670503 0.623468645028066 GO:0022853 active monoatomic ion transmembrane transporter activity 4/443 118/18639 0.0338983050847458 1.42625396946857 0.308379445585202 0.623468645028066 GO:0005254 chloride channel activity 3/443 83/18639 0.036144578313253 1.52076477467432 0.315798147074047 0.623468645028066 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/443 48/18639 0.0416666666666667 1.75310383747178 0.316552496107608 0.623468645028066 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/443 48/18639 0.0416666666666667 1.75310383747178 0.316552496107608 0.623468645028066 GO:0032266 phosphatidylinositol-3-phosphate binding 2/443 48/18639 0.0416666666666667 1.75310383747178 0.316552496107608 0.623468645028066 GO:0005096 GTPase activator activity 8/443 271/18639 0.029520295202952 1.24205142728628 0.31700408498717 0.623468645028066 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0004707 MAP kinase activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0005024 transforming growth factor beta receptor activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0005521 lamin binding 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0008296 3'-5'-DNA exonuclease activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0015378 sodium:chloride symporter activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0015923 mannosidase activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0016722 oxidoreductase activity, acting on metal ions 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0030275 LRR domain binding 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.623468645028066 GO:0051117 ATPase binding 3/443 84/18639 0.0357142857142857 1.50266043211867 0.322323121450253 0.623468645028066 GO:0015108 chloride transmembrane transporter activity 4/443 121/18639 0.0330578512396694 1.39089230080406 0.324521243439519 0.623468645028066 GO:0001222 transcription corepressor binding 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0005004 GPI-linked ephrin receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0005008 hepatocyte growth factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0005009 insulin receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0005011 macrophage colony-stimulating factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0005020 stem cell factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0008288 boss receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0036332 placental growth factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0038062 protein tyrosine kinase collagen receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0060175 brain-derived neurotrophic factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0060590 ATPase regulator activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.623468645028066 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/443 122/18639 0.0327868852459016 1.37949154424009 0.329915377096416 0.624258198993761 GO:0005006 epidermal growth factor receptor activity 2/443 50/18639 0.04 1.68297968397291 0.334055993991965 0.624258198993761 GO:0005007 fibroblast growth factor receptor activity 2/443 50/18639 0.04 1.68297968397291 0.334055993991965 0.624258198993761 GO:0005017 platelet-derived growth factor receptor activity 2/443 50/18639 0.04 1.68297968397291 0.334055993991965 0.624258198993761 GO:0005019 platelet-derived growth factor beta-receptor activity 2/443 50/18639 0.04 1.68297968397291 0.334055993991965 0.624258198993761 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.624258198993761 GO:0004659 prenyltransferase activity 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.624258198993761 GO:0008484 sulfuric ester hydrolase activity 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.624258198993761 GO:0008569 minus-end-directed microtubule motor activity 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.624258198993761 GO:0031489 myosin V binding 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.624258198993761 GO:0046965 nuclear retinoid X receptor binding 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.624258198993761 GO:0048038 quinone binding 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.624258198993761 GO:0070403 NAD+ binding 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.624258198993761 GO:1990226 histone methyltransferase binding 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.624258198993761 GO:0016829 lyase activity 6/443 200/18639 0.03 1.26223476297968 0.340083258992093 0.626904432799108 GO:0003743 translation initiation factor activity 2/443 51/18639 0.0392156862745098 1.64998008232638 0.342759715198576 0.626904432799108 GO:0005010 insulin-like growth factor receptor activity 2/443 51/18639 0.0392156862745098 1.64998008232638 0.342759715198576 0.626904432799108 GO:0005021 vascular endothelial growth factor receptor activity 2/443 51/18639 0.0392156862745098 1.64998008232638 0.342759715198576 0.626904432799108 GO:0005030 neurotrophin receptor activity 2/443 51/18639 0.0392156862745098 1.64998008232638 0.342759715198576 0.626904432799108 GO:0030246 carbohydrate binding 8/443 280/18639 0.0285714285714286 1.20212834569494 0.348963322442984 0.626904432799108 GO:0005080 protein kinase C binding 2/443 52/18639 0.0384615384615385 1.6182496961278 0.351426885271263 0.626904432799108 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0004970 glutamate-gated receptor activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0008308 voltage-gated monoatomic anion channel activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0015280 ligand-gated sodium channel activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0015373 monoatomic anion:sodium symporter activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0016854 racemase and epimerase activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0031690 adrenergic receptor binding 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0035615 clathrin adaptor activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0050811 GABA receptor binding 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0070064 proline-rich region binding 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0098641 cadherin binding involved in cell-cell adhesion 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.626904432799108 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/443 89/18639 0.0337078651685393 1.41824130671875 0.354920706336064 0.629067009424615 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/443 89/18639 0.0337078651685393 1.41824130671875 0.354920706336064 0.629067009424615 GO:0004864 protein phosphatase inhibitor activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.629067009424615 GO:0005003 ephrin receptor activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.629067009424615 GO:0005005 transmembrane-ephrin receptor activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.629067009424615 GO:0017046 peptide hormone binding 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.629067009424615 GO:0038064 collagen receptor activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.629067009424615 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.629067009424615 GO:0140793 histone H2AXY142 phosphatase activity 3/443 90/18639 0.0333333333333333 1.40248306997743 0.361422232181403 0.629067009424615 GO:0035091 phosphatidylinositol binding 8/443 284/18639 0.028169014084507 1.1851969605443 0.363306148922461 0.629067009424615 GO:0003756 protein disulfide isomerase activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.629067009424615 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.629067009424615 GO:0008301 DNA binding, bending 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.629067009424615 GO:0015245 fatty acid transmembrane transporter activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.629067009424615 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.629067009424615 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.629067009424615 GO:0042800 histone H3K4 methyltransferase activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.629067009424615 GO:0035591 signaling adaptor activity 4/443 129/18639 0.0310077519379845 1.30463541393249 0.36774987452446 0.629067009424615 GO:0003925 G protein activity 2/443 54/18639 0.037037037037037 1.55831452219714 0.368639038779792 0.629067009424615 GO:0015485 cholesterol binding 2/443 54/18639 0.037037037037037 1.55831452219714 0.368639038779792 0.629067009424615 GO:0051287 NAD binding 2/443 54/18639 0.037037037037037 1.55831452219714 0.368639038779792 0.629067009424615 GO:0140463 chromatin-protein adaptor activity 2/443 54/18639 0.037037037037037 1.55831452219714 0.368639038779792 0.629067009424615 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/443 130/18639 0.0307692307692308 1.29459975690224 0.373152857744004 0.635525960845257 GO:0043178 alcohol binding 3/443 92/18639 0.0326086956521739 1.37199430758661 0.37439377575618 0.636396437542669 GO:0051213 dioxygenase activity 3/443 93/18639 0.032258064516129 1.35724168062332 0.380860614475556 0.640656047823348 GO:0010851 cyclase regulator activity 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.640656047823348 GO:0015464 acetylcholine receptor activity 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.640656047823348 GO:0016408 C-acyltransferase activity 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.640656047823348 GO:0042288 MHC class I protein binding 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.640656047823348 GO:0140664 ATP-dependent DNA damage sensor activity 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.640656047823348 GO:0140939 histone H4 methyltransferase activity 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.640656047823348 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/443 132/18639 0.0303030303030303 1.27498460907039 0.383947206796267 0.642614134983387 GO:0019212 phosphatase inhibitor activity 2/443 56/18639 0.0357142857142857 1.50266043211867 0.385669059537044 0.644259425127017 GO:0042562 hormone binding 3/443 94/18639 0.0319148936170213 1.34280293934009 0.38731278514731 0.645768161851728 GO:0004867 serine-type endopeptidase inhibitor activity 3/443 95/18639 0.0315789473684211 1.32866817155756 0.393748807807313 0.649084727157236 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/443 57/18639 0.0350877192982456 1.47629796839729 0.39410915829109 0.649084727157236 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.649084727157236 GO:0001846 opsonin binding 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.649084727157236 GO:0008373 sialyltransferase activity 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.649084727157236 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.649084727157236 GO:0019200 carbohydrate kinase activity 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.649084727157236 GO:0070182 DNA polymerase binding 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.649084727157236 GO:0072542 protein phosphatase activator activity 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.649084727157236 GO:0140312 cargo adaptor activity 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.649084727157236 GO:0004896 cytokine receptor activity 3/443 96/18639 0.03125 1.31482787810384 0.40016724570595 0.653456625946794 GO:0044325 transmembrane transporter binding 4/443 136/18639 0.0294117647058824 1.23748506174479 0.405462673175012 0.660866263567496 GO:0004252 serine-type endopeptidase activity 5/443 176/18639 0.0284090909090909 1.19529807100349 0.407447384397853 0.662862162677104 GO:0045309 protein phosphorylated amino acid binding 2/443 59/18639 0.0338983050847458 1.42625396946857 0.410827614570766 0.663849624842557 GO:0070888 E-box binding 2/443 59/18639 0.0338983050847458 1.42625396946857 0.410827614570766 0.663849624842557 GO:0015377 chloride:monoatomic cation symporter activity 1/443 22/18639 0.0454545454545455 1.91247691360558 0.411099538319932 0.663849624842557 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/443 22/18639 0.0454545454545455 1.91247691360558 0.411099538319932 0.663849624842557 GO:0043021 ribonucleoprotein complex binding 5/443 177/18639 0.0282485875706215 1.18854497455714 0.412147912333834 0.664312346682261 GO:0004725 protein tyrosine phosphatase activity 3/443 98/18639 0.0306122448979592 1.28799465610172 0.412945833991577 0.664370419263202 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/443 60/18639 0.0333333333333333 1.40248306997743 0.419101625894187 0.671795253271564 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/443 60/18639 0.0333333333333333 1.40248306997743 0.419101625894187 0.671795253271564 GO:0000295 adenine nucleotide transmembrane transporter activity 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.672773626998397 GO:0003887 DNA-directed DNA polymerase activity 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.672773626998397 GO:0005158 insulin receptor binding 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.672773626998397 GO:0005283 amino acid:sodium symporter activity 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.672773626998397 GO:0017134 fibroblast growth factor binding 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.672773626998397 GO:0043274 phospholipase binding 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.672773626998397 GO:0140103 catalytic activity, acting on a glycoprotein 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.672773626998397 GO:0015179 L-amino acid transmembrane transporter activity 2/443 62/18639 0.032258064516129 1.35724168062332 0.435469338733766 0.67653052906684 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0004806 triacylglycerol lipase activity 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0015149 hexose transmembrane transporter activity 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0030552 cAMP binding 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0050431 transforming growth factor beta binding 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0055056 D-glucose transmembrane transporter activity 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0140612 DNA damage sensor activity 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.67653052906684 GO:0005507 copper ion binding 2/443 63/18639 0.0317460317460317 1.33569816188326 0.443559464481893 0.67653052906684 GO:0005253 monoatomic anion channel activity 3/443 103/18639 0.029126213592233 1.2254706436696 0.444492139139541 0.67653052906684 GO:0019903 protein phosphatase binding 4/443 144/18639 0.0277777777777778 1.16873589164786 0.448001400623463 0.67653052906684 GO:0019955 cytokine binding 4/443 144/18639 0.0277777777777778 1.16873589164786 0.448001400623463 0.67653052906684 GO:0061134 peptidase regulator activity 6/443 226/18639 0.0265486725663717 1.11702191414131 0.450065804162085 0.67653052906684 GO:0004536 DNA nuclease activity 2/443 64/18639 0.03125 1.31482787810384 0.451584916259651 0.67653052906684 GO:0000030 mannosyltransferase activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0001848 complement binding 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0008139 nuclear localization sequence binding 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0015645 fatty acid ligase activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0019211 phosphatase activator activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0019707 protein-cysteine S-acyltransferase activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0042974 nuclear retinoic acid receptor binding 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0120515 fatty acid-CoA ligase activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.67653052906684 GO:0019843 rRNA binding 2/443 65/18639 0.0307692307692308 1.29459975690224 0.459544194793628 0.67653052906684 GO:0120013 lipid transfer activity 2/443 65/18639 0.0307692307692308 1.29459975690224 0.459544194793628 0.67653052906684 GO:0160215 deacylase activity 2/443 65/18639 0.0307692307692308 1.29459975690224 0.459544194793628 0.67653052906684 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 6/443 229/18639 0.0262008733624454 1.10238843928357 0.462605895632971 0.67653052906684 GO:0004435 phosphatidylinositol phospholipase C activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0004529 DNA exonuclease activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0005160 transforming growth factor beta receptor binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0005227 calcium-activated cation channel activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0008066 glutamate receptor activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0008157 protein phosphatase 1 binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0015145 monosaccharide transmembrane transporter activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0015216 purine nucleotide transmembrane transporter activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0034237 protein kinase A regulatory subunit binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0050681 nuclear androgen receptor binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0097602 cullin family protein binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.67653052906684 GO:0141003 histone H2AX kinase activity 9/443 354/18639 0.0254237288135593 1.06969047710143 0.466198766574661 0.67653052906684 GO:0000287 magnesium ion binding 6/443 230/18639 0.0260869565217391 1.09759544606929 0.466770224939873 0.67653052906684 GO:0019209 kinase activator activity 4/443 148/18639 0.027027027027027 1.13714843511683 0.46892104489549 0.67653052906684 GO:0019902 phosphatase binding 5/443 190/18639 0.0263157894736842 1.10722347629797 0.472549886867486 0.67653052906684 GO:0016791 phosphatase activity 7/443 273/18639 0.0256410256410256 1.07883313075187 0.473134062688375 0.67653052906684 GO:0008509 monoatomic anion transmembrane transporter activity 4/443 149/18639 0.0268456375838926 1.12951656642477 0.474106576985375 0.67653052906684 GO:0016500 protein-hormone receptor activity 2/443 67/18639 0.0298507462686567 1.25595498803949 0.475258767830061 0.67653052906684 GO:0140996 histone H3 kinase activity 9/443 357/18639 0.0252100840336134 1.06070148149553 0.476246134986061 0.67653052906684 GO:0001671 ATPase activator activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0005044 scavenger receptor activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0008266 poly(U) RNA binding 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0008320 protein transmembrane transporter activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0008395 steroid hydroxylase activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0016405 CoA-ligase activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0023026 MHC class II protein complex binding 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0035255 ionotropic glutamate receptor binding 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.67653052906684 GO:0003777 microtubule motor activity 2/443 68/18639 0.0294117647058824 1.23748506174479 0.483011584005396 0.680890558956045 GO:0032934 sterol binding 2/443 68/18639 0.0294117647058824 1.23748506174479 0.483011584005396 0.680890558956045 GO:0005125 cytokine activity 6/443 234/18639 0.0256410256410256 1.07883313075187 0.483338596323156 0.680890558956045 GO:0035173 histone kinase activity 9/443 360/18639 0.025 1.05186230248307 0.486252553103369 0.681438187896494 GO:0005242 inward rectifier potassium channel activity 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.681438187896494 GO:0019789 SUMO transferase activity 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.681438187896494 GO:0051019 mitogen-activated protein kinase binding 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.681438187896494 GO:0051119 sugar transmembrane transporter activity 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.681438187896494 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.681438187896494 GO:0008080 N-acetyltransferase activity 2/443 69/18639 0.0289855072463768 1.21955049563254 0.490693262222677 0.681438187896494 GO:0098960 postsynaptic neurotransmitter receptor activity 2/443 69/18639 0.0289855072463768 1.21955049563254 0.490693262222677 0.681438187896494 GO:0008236 serine-type peptidase activity 5/443 194/18639 0.0257731958762887 1.08439412627121 0.490760529815365 0.681438187896494 GO:0043022 ribosome binding 3/443 112/18639 0.0267857142857143 1.126995324089 0.499459085834646 0.688225990712914 GO:0004629 phospholipase C activity 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.688225990712914 GO:0005416 amino acid:monoatomic cation symporter activity 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.688225990712914 GO:0016417 S-acyltransferase activity 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.688225990712914 GO:0099604 ligand-gated calcium channel activity 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.688225990712914 GO:0140299 molecular sensor activity 2/443 71/18639 0.028169014084507 1.1851969605443 0.505839279389523 0.688225990712914 GO:0017171 serine hydrolase activity 5/443 198/18639 0.0252525252525253 1.06248717422532 0.508739790632527 0.688225990712914 GO:0005518 collagen binding 2/443 72/18639 0.0277777777777778 1.16873589164786 0.513301871000992 0.688225990712914 GO:0001965 G-protein alpha-subunit binding 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.688225990712914 GO:0008187 poly-pyrimidine tract binding 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.688225990712914 GO:0015215 nucleotide transmembrane transporter activity 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.688225990712914 GO:0022839 monoatomic ion-gated channel activity 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.688225990712914 GO:0033612 receptor serine/threonine kinase binding 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.688225990712914 GO:0048019 receptor antagonist activity 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.688225990712914 GO:0035401 histone H3Y41 kinase activity 3/443 115/18639 0.0260869565217391 1.09759544606929 0.517166739228325 0.688225990712914 GO:0140801 histone H2AXY142 kinase activity 3/443 115/18639 0.0260869565217391 1.09759544606929 0.517166739228325 0.688225990712914 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 6/443 243/18639 0.0246913580246914 1.03887634813143 0.519997253770998 0.688225990712914 GO:0043539 protein serine/threonine kinase activator activity 2/443 73/18639 0.0273972602739726 1.15272581094035 0.52068982294023 0.688225990712914 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/443 31/18639 0.032258064516129 1.35724168062332 0.525879381148706 0.688225990712914 GO:0005452 solute:inorganic anion antiporter activity 1/443 31/18639 0.032258064516129 1.35724168062332 0.525879381148706 0.688225990712914 GO:0008327 methyl-CpG binding 1/443 31/18639 0.032258064516129 1.35724168062332 0.525879381148706 0.688225990712914 GO:0016878 acid-thiol ligase activity 1/443 31/18639 0.032258064516129 1.35724168062332 0.525879381148706 0.688225990712914 GO:0072349 modified amino acid transmembrane transporter activity 1/443 31/18639 0.032258064516129 1.35724168062332 0.525879381148706 0.688225990712914 GO:0031491 nucleosome binding 2/443 74/18639 0.027027027027027 1.13714843511683 0.528002461267761 0.688225990712914 GO:0004676 3-phosphoinositide-dependent protein kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0004711 ribosomal protein S6 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0035175 histone H3S10 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0035979 histone H2AXS139 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0044022 histone H3S28 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0044023 histone H4S1 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0044024 histone H2AS1 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0044025 histone H2BS14 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0072354 histone H3T3 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0072371 histone H2AS121 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0072518 Rho-dependent protein serine/threonine kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0140823 histone H2BS36 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0140855 histone H3S57 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0140995 histone H2A kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0140997 histone H4 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0140998 histone H2B kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:1990244 histone H2AT120 kinase activity 6/443 245/18639 0.0244897959183673 1.03039572488137 0.52800824287493 0.688225990712914 GO:0099106 ion channel regulator activity 4/443 160/18639 0.025 1.05186230248307 0.529754461171937 0.688837366903369 GO:0004677 DNA-dependent protein kinase activity 6/443 246/18639 0.024390243902439 1.02620712437373 0.531993377834477 0.688837366903369 GO:0140857 histone H3T45 kinase activity 6/443 246/18639 0.024390243902439 1.02620712437373 0.531993377834477 0.688837366903369 GO:0019003 GDP binding 2/443 75/18639 0.0266666666666667 1.12198645598194 0.535239186008723 0.688837366903369 GO:0035402 histone H3T11 kinase activity 6/443 247/18639 0.0242914979757085 1.02205243965966 0.535964544589481 0.688837366903369 GO:0035403 histone H3T6 kinase activity 6/443 247/18639 0.0242914979757085 1.02205243965966 0.535964544589481 0.688837366903369 GO:0022884 macromolecule transmembrane transporter activity 1/443 32/18639 0.03125 1.31482787810384 0.537166754007214 0.688837366903369 GO:0030515 snoRNA binding 1/443 32/18639 0.03125 1.31482787810384 0.537166754007214 0.688837366903369 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/443 32/18639 0.03125 1.31482787810384 0.537166754007214 0.688837366903369 GO:0043425 bHLH transcription factor binding 1/443 32/18639 0.03125 1.31482787810384 0.537166754007214 0.688837366903369 GO:0140142 nucleocytoplasmic carrier activity 1/443 32/18639 0.03125 1.31482787810384 0.537166754007214 0.688837366903369 GO:0008083 growth factor activity 4/443 162/18639 0.0246913580246914 1.03887634813143 0.539564365770953 0.690339455021186 GO:0004679 AMP-activated protein kinase activity 6/443 248/18639 0.0241935483870968 1.01793126046749 0.539921454500514 0.690339455021186 GO:0005525 GTP binding 9/443 378/18639 0.0238095238095238 1.00177362141245 0.54512663019349 0.695974262853183 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/443 33/18639 0.0303030303030303 1.27498460907039 0.548186000955932 0.696437560675504 GO:0071889 14-3-3 protein binding 1/443 33/18639 0.0303030303030303 1.27498460907039 0.548186000955932 0.696437560675504 GO:0140311 protein sequestering activity 1/443 33/18639 0.0303030303030303 1.27498460907039 0.548186000955932 0.696437560675504 GO:0015081 sodium ion transmembrane transporter activity 4/443 164/18639 0.024390243902439 1.02620712437373 0.54926979761193 0.696437560675504 GO:0051540 metal cluster binding 2/443 77/18639 0.025974025974026 1.09284395063176 0.549482846037554 0.696437560675504 GO:0015103 inorganic anion transmembrane transporter activity 4/443 165/18639 0.0242424242424242 1.01998768725631 0.55408227810036 0.70124781785706 GO:0008175 tRNA methyltransferase activity 1/443 34/18639 0.0294117647058824 1.23748506174479 0.558943477123649 0.702303619671213 GO:0015020 glucuronosyltransferase activity 1/443 34/18639 0.0294117647058824 1.23748506174479 0.558943477123649 0.702303619671213 GO:0016831 carboxy-lyase activity 1/443 34/18639 0.0294117647058824 1.23748506174479 0.558943477123649 0.702303619671213 GO:0019825 oxygen binding 1/443 34/18639 0.0294117647058824 1.23748506174479 0.558943477123649 0.702303619671213 GO:0090482 vitamin transmembrane transporter activity 1/443 34/18639 0.0294117647058824 1.23748506174479 0.558943477123649 0.702303619671213 GO:0001664 G protein-coupled receptor binding 7/443 297/18639 0.0235690235690236 0.991654695943635 0.562157519347372 0.705137464876671 GO:0015370 solute:sodium symporter activity 2/443 79/18639 0.0253164556962025 1.06517701517273 0.563417366564896 0.705137464876671 GO:0016874 ligase activity 4/443 167/18639 0.0239520958083832 1.00777226585204 0.563624785572294 0.705137464876671 GO:0016247 channel regulator activity 4/443 168/18639 0.0238095238095238 1.00177362141245 0.568354064439061 0.706339086434204 GO:0005343 organic acid:sodium symporter activity 1/443 35/18639 0.0285714285714286 1.20212834569494 0.569445387343171 0.706339086434204 GO:0016229 steroid dehydrogenase activity 1/443 35/18639 0.0285714285714286 1.20212834569494 0.569445387343171 0.706339086434204 GO:0034061 DNA polymerase activity 1/443 35/18639 0.0285714285714286 1.20212834569494 0.569445387343171 0.706339086434204 GO:0043015 gamma-tubulin binding 1/443 35/18639 0.0285714285714286 1.20212834569494 0.569445387343171 0.706339086434204 GO:0140566 histone reader activity 1/443 35/18639 0.0285714285714286 1.20212834569494 0.569445387343171 0.706339086434204 GO:0000049 tRNA binding 2/443 80/18639 0.025 1.05186230248307 0.57026789992155 0.706354557857374 GO:0015101 organic cation transmembrane transporter activity 2/443 81/18639 0.0246913580246914 1.03887634813143 0.577040305590823 0.711966862840211 GO:0141108 transporter regulator activity 4/443 170/18639 0.0235294117647059 0.989988049395831 0.57772691221479 0.711966862840211 GO:0004190 aspartic-type endopeptidase activity 1/443 36/18639 0.0277777777777778 1.16873589164786 0.579697789697879 0.711966862840211 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/443 36/18639 0.0277777777777778 1.16873589164786 0.579697789697879 0.711966862840211 GO:0005484 SNAP receptor activity 1/443 36/18639 0.0277777777777778 1.16873589164786 0.579697789697879 0.711966862840211 GO:0045505 dynein intermediate chain binding 1/443 36/18639 0.0277777777777778 1.16873589164786 0.579697789697879 0.711966862840211 GO:0008201 heparin binding 4/443 172/18639 0.0232558139534884 0.978476560449367 0.58698330068322 0.718252340120038 GO:0022829 wide pore channel activity 1/443 37/18639 0.027027027027027 1.13714843511683 0.589706598984759 0.718252340120038 GO:0023023 MHC protein complex binding 1/443 37/18639 0.027027027027027 1.13714843511683 0.589706598984759 0.718252340120038 GO:0030551 cyclic nucleotide binding 1/443 37/18639 0.027027027027027 1.13714843511683 0.589706598984759 0.718252340120038 GO:0070001 aspartic-type peptidase activity 1/443 37/18639 0.027027027027027 1.13714843511683 0.589706598984759 0.718252340120038 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/443 128/18639 0.0234375 0.986120908577878 0.589757655419664 0.718252340120038 GO:0042887 amide transmembrane transporter activity 1/443 38/18639 0.0263157894736842 1.10722347629797 0.599477590095917 0.727446973727568 GO:0043531 ADP binding 1/443 38/18639 0.0263157894736842 1.10722347629797 0.599477590095917 0.727446973727568 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/443 130/18639 0.0230769230769231 0.97094981767668 0.600285067497563 0.727446973727568 GO:0004721 phosphoprotein phosphatase activity 4/443 175/18639 0.0228571428571429 0.96170267655595 0.600644290233772 0.727446973727568 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/443 39/18639 0.0256410256410256 1.07883313075187 0.609016401320448 0.736563525591444 GO:0016757 glycosyltransferase activity 6/443 267/18639 0.0224719101123595 0.945494204479164 0.61205463231414 0.73863580637564 GO:0019001 guanyl nucleotide binding 9/443 400/18639 0.0225 0.946676072234763 0.613271013550417 0.73863580637564 GO:0032561 guanyl ribonucleotide binding 9/443 400/18639 0.0225 0.946676072234763 0.613271013550417 0.73863580637564 GO:0004197 cysteine-type endopeptidase activity 2/443 88/18639 0.0227272727272727 0.956238456802791 0.622252039249055 0.745381054099828 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/443 88/18639 0.0227272727272727 0.956238456802791 0.622252039249055 0.745381054099828 GO:0001530 lipopolysaccharide binding 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.745381054099828 GO:0004812 aminoacyl-tRNA ligase activity 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.745381054099828 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.745381054099828 GO:0008227 G protein-coupled amine receptor activity 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.745381054099828 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.745381054099828 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.745381054099828 GO:0042287 MHC protein binding 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.745381054099828 GO:0140318 protein transporter activity 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.745381054099828 GO:0003727 single-stranded RNA binding 2/443 89/18639 0.0224719101123595 0.945494204479164 0.628397587132112 0.745527477522723 GO:0099094 ligand-gated monoatomic cation channel activity 3/443 136/18639 0.0220588235294118 0.928113796308591 0.630788810381191 0.746333572119944 GO:0140789 histone phosphatase activity 3/443 136/18639 0.0220588235294118 0.928113796308591 0.630788810381191 0.746333572119944 GO:0042578 phosphoric ester hydrolase activity 8/443 363/18639 0.0220385674931129 0.927261533869373 0.63522021374179 0.748783407071318 GO:0004520 DNA endonuclease activity 1/443 42/18639 0.0238095238095238 1.00177362141245 0.636294156697072 0.748783407071318 GO:0035198 miRNA binding 1/443 42/18639 0.0238095238095238 1.00177362141245 0.636294156697072 0.748783407071318 GO:0048487 beta-tubulin binding 1/443 42/18639 0.0238095238095238 1.00177362141245 0.636294156697072 0.748783407071318 GO:0015078 proton transmembrane transporter activity 4/443 185/18639 0.0216216216216216 0.909718748093466 0.64416422655038 0.756465862364356 GO:0030295 protein kinase activator activity 3/443 139/18639 0.0215827338129496 0.908082563294737 0.645425001833808 0.756465862364356 GO:0140767 enzyme-substrate adaptor activity 3/443 139/18639 0.0215827338129496 0.908082563294737 0.645425001833808 0.756465862364356 GO:0052689 carboxylic ester hydrolase activity 2/443 92/18639 0.0217391304347826 0.914662871724409 0.646367602804369 0.756553757913302 GO:0015276 ligand-gated monoatomic ion channel activity 4/443 186/18639 0.021505376344086 0.904827787082211 0.64834062813557 0.756678216526223 GO:0004713 protein tyrosine kinase activity 3/443 140/18639 0.0214285714285714 0.901596259271203 0.650211707672164 0.756678216526223 GO:0031406 carboxylic acid binding 4/443 187/18639 0.0213903743315508 0.899989135814391 0.652484509210172 0.756678216526223 GO:0001223 transcription coactivator binding 1/443 44/18639 0.0227272727272727 0.956238456802791 0.653415936977346 0.756678216526223 GO:0019205 nucleobase-containing compound kinase activity 1/443 44/18639 0.0227272727272727 0.956238456802791 0.653415936977346 0.756678216526223 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/443 44/18639 0.0227272727272727 0.956238456802791 0.653415936977346 0.756678216526223 GO:0030547 signaling receptor inhibitor activity 1/443 44/18639 0.0227272727272727 0.956238456802791 0.653415936977346 0.756678216526223 GO:0043014 alpha-tubulin binding 1/443 44/18639 0.0227272727272727 0.956238456802791 0.653415936977346 0.756678216526223 GO:0022834 ligand-gated channel activity 4/443 188/18639 0.0212765957446809 0.89520195956006 0.656595757157844 0.759352122336393 GO:0016410 N-acyltransferase activity 2/443 94/18639 0.0212765957446809 0.89520195956006 0.65796140244835 0.759923633026438 GO:0043177 organic acid binding 4/443 189/18639 0.0211640211640212 0.890465441255509 0.660674269867269 0.761185618793257 GO:0046915 transition metal ion transmembrane transporter activity 1/443 45/18639 0.0222222222222222 0.934988713318284 0.661672820006065 0.761185618793257 GO:0051539 4 iron, 4 sulfur cluster binding 1/443 45/18639 0.0222222222222222 0.934988713318284 0.661672820006065 0.761185618793257 GO:0008276 protein methyltransferase activity 2/443 95/18639 0.0210526315789474 0.885778781038375 0.663643393730952 0.762446692138855 GO:0016407 acetyltransferase activity 2/443 96/18639 0.0208333333333333 0.876551918735892 0.669249269220846 0.76787547731655 GO:0008194 UDP-glycosyltransferase activity 3/443 145/18639 0.0206896551724138 0.870506733089437 0.673452658300261 0.771682940916987 GO:0030594 neurotransmitter receptor activity 2/443 97/18639 0.0206185567010309 0.867515301016965 0.674779428469099 0.772188532316344 GO:0005504 fatty acid binding 1/443 47/18639 0.0212765957446809 0.89520195956006 0.677602415640338 0.773389144552847 GO:0140938 histone H3 methyltransferase activity 1/443 47/18639 0.0212765957446809 0.89520195956006 0.677602415640338 0.773389144552847 GO:0015291 secondary active transmembrane transporter activity 6/443 287/18639 0.0209059233449477 0.879606106606052 0.680712587832113 0.775923368090984 GO:0015085 calcium ion transmembrane transporter activity 3/443 147/18639 0.0204081632653061 0.858663104067812 0.682425693417276 0.776860580495907 GO:0005539 glycosaminoglycan binding 5/443 242/18639 0.0206611570247934 0.869307688002537 0.685041528646557 0.777071436583465 GO:0038187 pattern recognition receptor activity 1/443 48/18639 0.0208333333333333 0.876551918735892 0.685284328821886 0.777071436583465 GO:0140693 molecular condensate scaffold activity 1/443 48/18639 0.0208333333333333 0.876551918735892 0.685284328821886 0.777071436583465 GO:0043130 ubiquitin binding 2/443 100/18639 0.02 0.841489841986456 0.690919956070315 0.781510095095239 GO:0016758 hexosyltransferase activity 4/443 197/18639 0.0203045685279188 0.854304408108077 0.692114951559234 0.781510095095239 GO:0016763 pentosyltransferase activity 1/443 49/18639 0.0204081632653061 0.858663104067812 0.692783604941078 0.781510095095239 GO:0035254 glutamate receptor binding 1/443 49/18639 0.0204081632653061 0.858663104067812 0.692783604941078 0.781510095095239 GO:0015605 organophosphate ester transmembrane transporter activity 1/443 50/18639 0.02 0.841489841986456 0.700104576593101 0.788748308513158 GO:0004722 protein serine/threonine phosphatase activity 2/443 103/18639 0.0194174757281553 0.816980429113064 0.706395573744565 0.790670878425519 GO:0005048 signal sequence binding 1/443 51/18639 0.0196078431372549 0.824990041163192 0.707251473820991 0.790670878425519 GO:0005272 sodium channel activity 1/443 51/18639 0.0196078431372549 0.824990041163192 0.707251473820991 0.790670878425519 GO:0016597 amino acid binding 1/443 51/18639 0.0196078431372549 0.824990041163192 0.707251473820991 0.790670878425519 GO:0016830 carbon-carbon lyase activity 1/443 51/18639 0.0196078431372549 0.824990041163192 0.707251473820991 0.790670878425519 GO:0030544 Hsp70 protein binding 1/443 51/18639 0.0196078431372549 0.824990041163192 0.707251473820991 0.790670878425519 GO:0140375 immune receptor activity 3/443 156/18639 0.0192307692307692 0.8091248480639 0.720532282031464 0.799115870862315 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.799115870862315 GO:0034212 protein N-acetyltransferase activity 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.799115870862315 GO:0051018 protein kinase A binding 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.799115870862315 GO:0140296 general transcription initiation factor binding 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.799115870862315 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.799115870862315 GO:0008013 beta-catenin binding 2/443 106/18639 0.0188679245283019 0.793858341496657 0.721220401798901 0.799115870862315 GO:0017069 snRNA binding 1/443 54/18639 0.0185185185185185 0.77915726109857 0.727688531572133 0.804040083938333 GO:0050661 NADP binding 1/443 54/18639 0.0185185185185185 0.77915726109857 0.727688531572133 0.804040083938333 GO:0005516 calmodulin binding 4/443 207/18639 0.0193236714975845 0.81303366375503 0.728430809990004 0.804040083938333 GO:0008374 O-acyltransferase activity 1/443 55/18639 0.0181818181818182 0.764990765442233 0.734179464072189 0.809360926259101 GO:0015079 potassium ion transmembrane transporter activity 3/443 160/18639 0.01875 0.788896726862302 0.736290549176442 0.810663331921537 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/443 56/18639 0.0178571428571429 0.751330216059336 0.740516016881919 0.814287473797015 GO:0008408 3'-5' exonuclease activity 1/443 58/18639 0.0172413793103448 0.725422277574531 0.752740551244255 0.824610252116822 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/443 58/18639 0.0172413793103448 0.725422277574531 0.752740551244255 0.824610252116822 GO:0061980 regulatory RNA binding 1/443 58/18639 0.0172413793103448 0.725422277574531 0.752740551244255 0.824610252116822 GO:0015459 potassium channel regulator activity 1/443 59/18639 0.0169491525423729 0.713126984734285 0.758635601876557 0.828985269218493 GO:0031593 polyubiquitin modification-dependent protein binding 1/443 59/18639 0.0169491525423729 0.713126984734285 0.758635601876557 0.828985269218493 GO:0001098 basal transcription machinery binding 1/443 60/18639 0.0166666666666667 0.701241534988713 0.7643904150288 0.832145370668057 GO:0001099 basal RNA polymerase II transcription machinery binding 1/443 60/18639 0.0166666666666667 0.701241534988713 0.7643904150288 0.832145370668057 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/443 60/18639 0.0166666666666667 0.701241534988713 0.7643904150288 0.832145370668057 GO:0015294 solute:monoatomic cation symporter activity 2/443 116/18639 0.0172413793103448 0.725422277574531 0.766140984686386 0.833011145444549 GO:0022836 gated channel activity 6/443 318/18639 0.0188679245283019 0.793858341496657 0.7704960254119 0.836703031331477 GO:0022824 transmitter-gated monoatomic ion channel activity 1/443 63/18639 0.0158730158730159 0.667849080941632 0.780846324716345 0.844786594482199 GO:0022835 transmitter-gated channel activity 1/443 63/18639 0.0158730158730159 0.667849080941632 0.780846324716345 0.844786594482199 GO:1901682 sulfur compound transmembrane transporter activity 1/443 63/18639 0.0158730158730159 0.667849080941632 0.780846324716345 0.844786594482199 GO:0032182 ubiquitin-like protein binding 2/443 120/18639 0.0166666666666667 0.701241534988713 0.782274282884848 0.845282744331583 GO:0005126 cytokine receptor binding 5/443 275/18639 0.0181818181818182 0.764990765442233 0.785753546337331 0.847991450997714 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/443 122/18639 0.0163934426229508 0.689745772120046 0.789969228834987 0.851487228113854 GO:0005267 potassium channel activity 2/443 124/18639 0.0161290322580645 0.678620840311658 0.797423726563222 0.858461098226086 GO:0008173 RNA methyltransferase activity 1/443 67/18639 0.0149253731343284 0.627977494019743 0.801017369658844 0.860205845249399 GO:0042054 histone methyltransferase activity 1/443 67/18639 0.0149253731343284 0.627977494019743 0.801017369658844 0.860205845249399 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/443 68/18639 0.0147058823529412 0.618742530872394 0.805763724668597 0.863176864755549 GO:0140223 general transcription initiation factor activity 1/443 68/18639 0.0147058823529412 0.618742530872394 0.805763724668597 0.863176864755549 GO:0002039 p53 binding 1/443 69/18639 0.0144927536231884 0.609775247816272 0.810397113822214 0.866012602025699 GO:0016279 protein-lysine N-methyltransferase activity 1/443 69/18639 0.0144927536231884 0.609775247816272 0.810397113822214 0.866012602025699 GO:0016278 lysine N-methyltransferase activity 1/443 70/18639 0.0142857142857143 0.601064172847468 0.814920219830655 0.869780210149732 GO:0005262 calcium channel activity 2/443 131/18639 0.0152671755725191 0.642358658004928 0.821701127034945 0.875945455714514 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/443 73/18639 0.0136986301369863 0.576362905470175 0.82785372155775 0.881426673013868 GO:0003684 damaged DNA binding 1/443 74/18639 0.0135135135135135 0.568574217558416 0.831961273068572 0.88471979282414 GO:0015297 antiporter activity 2/443 135/18639 0.0148148148148148 0.623325808878856 0.834373545092837 0.886204301243549 GO:0003725 double-stranded RNA binding 1/443 75/18639 0.0133333333333333 0.560993227990971 0.835971031001813 0.886820850405816 GO:0016779 nucleotidyltransferase activity 2/443 136/18639 0.0147058823529412 0.618742530872394 0.837412123222861 0.887270196172947 GO:0051536 iron-sulfur cluster binding 1/443 76/18639 0.0131578947368421 0.553611738148984 0.839885318508072 0.888810676867766 GO:0140101 catalytic activity, acting on a tRNA 2/443 139/18639 0.0143884892086331 0.605388375529824 0.846227854463232 0.894437198899319 GO:0033293 monocarboxylic acid binding 1/443 79/18639 0.0126582278481013 0.532588507586365 0.85107777176735 0.897200410398058 GO:0033192 calmodulin-dependent protein phosphatase activity 1/443 81/18639 0.0123456790123457 0.519438174065713 0.858102227376125 0.897200410398058 GO:0140791 histone H2AXS140 phosphatase activity 1/443 81/18639 0.0123456790123457 0.519438174065713 0.858102227376125 0.897200410398058 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/443 81/18639 0.0123456790123457 0.519438174065713 0.858102227376125 0.897200410398058 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/443 81/18639 0.0123456790123457 0.519438174065713 0.858102227376125 0.897200410398058 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/443 81/18639 0.0123456790123457 0.519438174065713 0.858102227376125 0.897200410398058 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/443 81/18639 0.0123456790123457 0.519438174065713 0.858102227376125 0.897200410398058 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/443 81/18639 0.0123456790123457 0.519438174065713 0.858102227376125 0.897200410398058 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/443 81/18639 0.0123456790123457 0.519438174065713 0.858102227376125 0.897200410398058 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/443 82/18639 0.0121951219512195 0.513103562186863 0.861489484261154 0.898587117554696 GO:0033549 MAP kinase phosphatase activity 1/443 82/18639 0.0121951219512195 0.513103562186863 0.861489484261154 0.898587117554696 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/443 83/18639 0.0120481927710843 0.506921591558106 0.864796061750636 0.90002000115719 GO:0015293 symporter activity 2/443 146/18639 0.0136986301369863 0.576362905470175 0.865133267134934 0.90002000115719 GO:0008168 methyltransferase activity 3/443 204/18639 0.0147058823529412 0.618742530872394 0.866563802077087 0.90002000115719 GO:0004527 exonuclease activity 1/443 84/18639 0.0119047619047619 0.500886810706224 0.86802387726284 0.90002000115719 GO:0017018 myosin phosphatase activity 1/443 84/18639 0.0119047619047619 0.500886810706224 0.86802387726284 0.90002000115719 GO:0008081 phosphoric diester hydrolase activity 1/443 87/18639 0.0114942528735632 0.483614851716354 0.87725325052368 0.908509304580343 GO:0061659 ubiquitin-like protein ligase activity 6/443 372/18639 0.0161290322580645 0.678620840311658 0.879815238227636 0.910081717360022 GO:0016741 transferase activity, transferring one-carbon groups 3/443 215/18639 0.013953488372093 0.58708593626962 0.888638740290138 0.918119646366114 GO:0140097 catalytic activity, acting on DNA 5/443 336/18639 0.0148809523809524 0.62610851338278 0.904350660494144 0.932654117475896 GO:0005249 voltage-gated potassium channel activity 1/443 98/18639 0.0102040816326531 0.429331552033906 0.905915180621656 0.932654117475896 GO:0008170 N-methyltransferase activity 1/443 98/18639 0.0102040816326531 0.429331552033906 0.905915180621656 0.932654117475896 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/443 167/18639 0.0119760479041916 0.503886132926022 0.909772735309804 0.935521020271402 GO:0005216 monoatomic ion channel activity 7/443 448/18639 0.015625 0.657413939051919 0.911036244042848 0.93571684900514 GO:0046873 metal ion transmembrane transporter activity 7/443 450/18639 0.0155555555555556 0.654492099322799 0.913251606800756 0.93688870721207 GO:0005244 voltage-gated monoatomic ion channel activity 2/443 173/18639 0.0115606936416185 0.486410313286969 0.919728662703572 0.942424669656304 GO:0003735 structural constituent of ribosome 2/443 175/18639 0.0114285714285714 0.480851338277975 0.922811356588664 0.943366357497438 GO:0022832 voltage-gated channel activity 2/443 175/18639 0.0114285714285714 0.480851338277975 0.922811356588664 0.943366357497438 GO:0061630 ubiquitin protein ligase activity 5/443 353/18639 0.0141643059490085 0.595955978743949 0.924995831660634 0.944492230922802 GO:0140104 molecular carrier activity 3/443 249/18639 0.0120481927710843 0.506921591558106 0.937681668733 0.956325631737048 GO:0008234 cysteine-type peptidase activity 2/443 187/18639 0.0106951871657754 0.449994567907196 0.939087728010946 0.95664076965601 GO:0019787 ubiquitin-like protein transferase activity 7/443 479/18639 0.0146137787056367 0.614867316691565 0.940411372932339 0.95687131528238 GO:0003697 single-stranded DNA binding 1/443 121/18639 0.00826446280991736 0.347723075201015 0.946071881692798 0.96150895202345 GO:0016755 aminoacyltransferase activity 7/443 496/18639 0.0141129032258065 0.593793235272701 0.95257677970779 0.966667765339308 GO:0004519 endonuclease activity 1/443 127/18639 0.0078740157480315 0.331295213380494 0.953364997926382 0.966667765339308 GO:0004842 ubiquitin-protein transferase activity 6/443 449/18639 0.0133630289532294 0.562242656115672 0.958007671732723 0.970247026423849 GO:0004518 nuclease activity 2/443 209/18639 0.00956937799043062 0.402626718653807 0.960835384078501 0.971650358581166 GO:0008094 ATP-dependent activity, acting on DNA 2/443 210/18639 0.00952380952380952 0.400709448564979 0.961621857173791 0.971650358581166 GO:0005261 monoatomic cation channel activity 4/443 341/18639 0.0117302052785924 0.493542429317569 0.963360614111668 0.972280619797887 GO:0022843 voltage-gated monoatomic cation channel activity 1/443 143/18639 0.00699300699300699 0.294227217477782 0.968352794960447 0.976189175960127 GO:0004386 helicase activity 1/443 155/18639 0.00645161290322581 0.271448336124663 0.976343194366898 0.983107696868285 GO:0140658 ATP-dependent chromatin remodeler activity 1/443 158/18639 0.00632911392405063 0.266294253793182 0.978003767035489 0.983643927168335 GO:0003730 mRNA 3'-UTR binding 2/443 262/18639 0.00763358778625954 0.321179329002464 0.986914348723679 0.991462341114111 GO:0140597 protein carrier chaperone 1/443 188/18639 0.00531914893617021 0.223800489890015 0.98938342444601 0.992799017395766 GO:0140098 catalytic activity, acting on RNA 2/443 387/18639 0.00516795865633075 0.217439235655415 0.999127959297262 0.999824341985045 GO:0030371 translation repressor activity 1/443 329/18639 0.00303951367781155 0.127885994222866 0.999659540324957 0.999824341985045 GO:0045182 translation regulator activity 1/443 356/18639 0.00280898876404494 0.118186775559895 0.999824341985045 0.999824341985045