category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	10/21	205/9376	21.7793263646922	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2/NFKB1	14.2519220294475
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	9/21	138/9376	29.1180124223602	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2	15.7655298936465
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	10/21	227/9376	19.6685546465282	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2/NFKB1	13.4899456467282
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	9/21	235/9376	17.0990881458967	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2	11.8416370192285
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	9/21	268/9376	14.9936034115139	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2	11.0118132417815
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	9/21	275/9376	14.6119480519481	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2	10.8546409489193
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	10/21	388/9376	11.507118311242	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2/NFKB1	10.014778378934
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	9/21	308/9376	13.0463821892393	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2	10.1847325710846
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	10/21	480/9376	9.3015873015873	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2/NFKB1	8.84622050575149
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	9/21	368/9376	10.9192546583851	MT-CO3/MT-CYB/MT-ND4/MT-CO1/MT-ATP6/MT-ND1/MT-ND3/MT-ND2/MT-CO2	9.19733807075009
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	5/21	157/9376	14.2189869578405	MT-CO3/MT-CYB/MT-CO1/MT-CO2/NFKB1	7.91369817539589
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	4/21	87/9376	20.527640941434	MT-CO3/MT-CYB/MT-CO1/MT-CO2	8.66958513162511
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	4/21	105/9376	17.0086167800454	NFKB1/TNFAIP3/CCL4/CCL4L2	7.8155322067734
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/21	227/9376	9.83427732326411	HLA-C/HLA-A/NFKB1/CCL4/CCL4L2	6.38367153619571
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/21	54/9376	24.8042328042328	HLA-C/HLA-A/CGA	8.3113181923383
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	4/21	149/9376	11.9859379993608	MT-ND4/MT-ND1/MT-ND3/MT-ND2	6.40432565344655
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	3/21	83/9376	16.1376936316695	NFKB1/CCL4/CCL4L2	6.5628756971349
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/21	205/9376	8.71173054587689	HLA-C/HLA-A/NFKB1/TNFAIP3	5.28924665424659
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	4/21	205/9376	8.71173054587689	HLA-C/HLA-A/NFKB1/EGR2	5.28924665424659
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	4/21	224/9376	7.97278911564626	HLA-C/HLA-A/NFKB1/EGR2	5.00432980566174
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	3/21	109/9376	12.2883355176933	NFKB1/CCL4/CCL4L2	5.61625691557725
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/21	39/9376	22.8962148962149	HLA-C/HLA-A	6.49188862545497
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/21	44/9376	20.2943722943723	HLA-C/HLA-A	6.07775258938215
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/21	45/9376	19.8433862433862	HLA-C/HLA-A	6.00308512814371
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/21	157/9376	8.53139217470428	HLA-C/HLA-A/NFKB1	4.50875431689547
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/21	180/9376	7.44126984126984	HLA-C/HLA-A/NFKB1	4.13410644017557
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	3/21	193/9376	6.940044411547	NFKB1/CCL4/CCL4L2	3.9504761486516
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	3/21	196/9376	6.83381924198251	HLA-C/HLA-A/NFKB1	3.91050687111891
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/21	70/9376	12.756462585034	HLA-C/HLA-A	4.67754044750789
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/21	71/9376	12.5767940979209	CGA/NFKB1	4.63908878556537
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/21	214/9376	6.25901201602136	HLA-C/HLA-A/NFKB1	3.68713717892135
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/21	82/9376	10.8896631823461	HLA-C/HLA-A	4.26148027537512
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/21	94/9376	9.49949341438703	NFKB1/TNFAIP3	3.92382451429012
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/21	100/9376	8.92952380952381	CCL4/CCL4L2	3.77694036015382
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/21	105/9376	8.50430839002268	NFKB1/EGR2	3.66366218378649
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	3/21	298/9376	4.49472674976031	TNFRSF9/CCL4/CCL4L2	2.90468911136329
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/21	119/9376	7.50380152060824	NFKB1/TNFAIP3	3.38282099809043
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/21	133/9376	6.71392767633369	HLA-C/HLA-A	3.14432531799709
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/21	136/9376	6.56582633053221	NFKB1/TNFAIP3	3.09767969654
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/21	333/9376	4.02230802230802	HLA-C/HLA-A/NFKB1	2.66059006421075
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/21	138/9376	6.47066942719117	NFKB1/ARHGEF28	3.06735771707866
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/21	155/9376	5.76098310291859	HLA-C/HLA-A	2.83169756826386
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/21	160/9376	5.58095238095238	HLA-C/HLA-A	2.76896792640301
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/21	163/9376	5.47823546596553	NFKB1/EGR2	2.73258437910808
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/21	187/9376	4.77514642220525	NFKB1/TNFAIP3	2.47055125250684
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/21	30/9376	14.8825396825397	NFKB1	3.60819543086179
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/21	226/9376	3.95111672987779	CGA/NFKB1	2.12766598377562
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/21	42/9376	10.6303854875283	KMO	2.96351962861283
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/21	49/9376	9.11175898931001	NFKB1	2.69721446446751
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/21	250/9376	3.57180952380952	HLA-C/HLA-A	1.95272893701444
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/21	52/9376	8.58608058608059	CGA	2.59891084203143
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/21	56/9376	7.97278911564626	NFKB1	2.47951064774318
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/21	59/9376	7.56739305891848	CGA	2.39747649130105
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/21	65/9376	6.86886446886447	CGA	2.24949993527613
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/21	66/9376	6.76479076479076	NFKB1	2.22666081262208
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/21	68/9376	6.56582633053221	NFKB1	2.18237465682867
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/21	70/9376	6.37823129251701	NFKB1	2.1398353650039
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/21	71/9376	6.28839704896043	NFKB1	2.11918284422588
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/21	72/9376	6.2010582010582	NFKB1	2.09892297143977
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/21	75/9376	5.95301587301587	CGA	2.04036995091541
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/21	77/9376	5.79839208410637	NFKB1	2.0030710782125
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/21	77/9376	5.79839208410637	NFKB1	2.0030710782125
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/21	78/9376	5.72405372405372	NFKB1	1.98490967235691
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/21	78/9376	5.72405372405372	NFKB1	1.98490967235691
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/21	90/9376	4.96084656084656	NFKB1	1.78882692563912
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/21	90/9376	4.96084656084656	NFKB1	1.78882692563912
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/21	91/9376	4.90633176347462	NFKB1	1.77407614728029
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/21	93/9376	4.80081925243216	NFKB1	1.74521085653402
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/21	93/9376	4.80081925243216	CGA	1.74521085653402
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/21	93/9376	4.80081925243216	NFKB1	1.74521085653402
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/21	101/9376	4.42055634134842	NFKB1	1.63747193649704
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/21	103/9376	4.33472029588534	NFKB1	1.61228303741094
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/21	103/9376	4.33472029588534	NFKB1	1.61228303741094
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/21	106/9376	4.21203953279425	NFKB1	1.57567751266775
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/21	109/9376	4.09611183923111	NFKB1	1.54040066413932
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/21	109/9376	4.09611183923111	NFKB1	1.54040066413932
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/21	110/9376	4.05887445887446	NFKB1	1.52892167483941
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/21	112/9376	3.98639455782313	NFKB1	1.50636533603146
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/21	120/9376	3.72063492063492	NFKB1	1.42109335216326
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/21	122/9376	3.65964090554255	NFKB1	1.40091427679087
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/21	125/9376	3.57180952380952	NFKB1	1.37142750691253
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/21	130/9376	3.43443223443223	NFKB1	1.32423728351828
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/21	137/9376	3.25895029544665	NFKB1	1.26190849724891
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/21	142/9376	3.14419852448021	NFKB1	1.21979716471112
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/21	142/9376	3.14419852448021	NFKB1	1.21979716471112
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/21	144/9376	3.1005291005291	NFKB1	1.20347047577224
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/21	154/9376	2.89919604205318	KMO	1.12587710481668
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/21	156/9376	2.86202686202686	NFKB1	1.11110773312401
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/21	168/9376	2.65759637188209	TNFAIP3	1.0271270403462
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/21	173/9376	2.58078722818607	NFKB1	0.994271861107208
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/21	181/9376	2.46671928439884	NFKB1	0.944025688681738
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/21	195/9376	2.28962148962149	NFKB1	0.862199889833102
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/21	200/9376	2.23238095238095	NFKB1	0.834654352198917
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/21	201/9376	2.22127457948353	NFKB1	0.829242780845132
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/21	216/9376	2.06701940035273	NFKB1	0.751665892413924
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/21	217/9376	2.05749396532807	NFKB1	0.746718867340673
NA	NA	hsa04081	Hormone signaling	1/21	219/9376	2.03870406610133	CGA	0.736903588962675
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/21	238/9376	1.87595038015206	NFKB1	0.648508685168727
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/21	238/9376	1.87595038015206	NFKB1	0.648508685168727
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/21	248/9376	1.80030721966206	NFKB1	0.605157122403723
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/21	253/9376	1.76472802559759	NFKB1	0.584213810466177
NA	NA	hsa04517	IgSF CAM signaling	1/21	299/9376	1.49323140627488	CRTAM	0.410665801711107
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/21	300/9376	1.48825396825397	NFKB1	0.407223240095259
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/21	323/9376	1.38227922748047	NFKB1	0.331252443333795
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/21	362/9376	1.23335964219942	NFKB1	0.21453326791502
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/21	370/9376	1.20669240669241	CGA	0.192190892031994
NA	NA	hsa04519	Cadherin signaling	1/21	404/9376	1.10513908533711	NFKB1	0.102349007195253