category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/25	42/9376	17.8590476190476	FTH1/SAT1	5.66174621338908
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/25	137/9376	8.21255474452555	FOS/GADD45G/MCL1	4.39707159055796
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	4/25	300/9376	5.00053333333333	FLT1/DUSP1/FOS/GADD45G	3.64131199021465
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/25	52/9376	14.4246153846154	CGA/CYP19A1	5.01913648337035
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/25	54/9376	13.8903703703704	CGA/HLA-A	4.9117283606495
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/25	168/9376	6.69714285714286	CSH1/LEP/MCL1	3.85261586938852
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/25	65/9376	11.5396923076923	CGA/KISS1	4.40872552242185
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	2/25	69/9376	10.8707246376812	FOS/FOSB	4.25495860233328
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/25	71/9376	10.5645070422535	CGA/FOS	4.18273346379678
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	4/25	370/9376	4.05448648648649	CGA/CSH1/LEP/KISS1	3.099557610413
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/25	76/9376	9.86947368421053	OLR1/PLIN2	4.01411476903923
NA	NA	hsa04081	Hormone signaling	3/25	219/9376	5.13753424657534	CGA/CSH1/LEP	3.20341840046203
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/25	87/9376	8.6216091954023	FOS/GADD45G	3.69273748615084
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/25	94/9376	7.97957446808511	FOS/FOSB	3.51640350350848
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/25	95/9376	7.89557894736842	FLT1/FOS	3.49270387005672
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/25	122/9376	6.14819672131148	CSH1/FOS	2.95935397677315
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	3/25	298/9376	3.77557046979866	CSH1/LEP/INHBA	2.5176300587755
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/25	142/9376	5.28225352112676	FOS/FOSB	2.65857077445799
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/25	142/9376	5.28225352112676	DUSP1/FOS	2.65857077445799
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/25	148/9376	5.06810810810811	FOS/GADD45G	2.57926618472481
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/25	154/9376	4.87064935064935	FOS/RGS2	2.50413792174738
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/25	155/9376	4.83922580645161	OLR1/HLA-A	2.49199466530736
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/25	157/9376	4.77757961783439	GADD45G/HLA-A	2.46801707039792
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/25	157/9376	4.77757961783439	LEP/FOS	2.46801707039792
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	3/25	362/9376	3.10806629834254	CSH1/FLT1/MCL1	2.11498059800158
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/25	37/9376	10.1362162162162	GADD45G	2.87901320832076
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/25	196/9376	3.8269387755102	FOS/HLA-A	2.06799608366891
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/25	39/9376	9.61641025641026	HLA-A	2.78792834354208
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/25	201/9376	3.73174129353234	FLT1/GADD45G	2.02423613787037
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/25	205/9376	3.65892682926829	GADD45G/HLA-A	1.99022228134853
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/25	43/9376	8.72186046511628	ACADVL	2.62405031702334
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/25	214/9376	3.50504672897196	FOS/HLA-A	1.91670020177496
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/25	44/9376	8.52363636363636	HLA-A	2.58638625765024
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/25	216/9376	3.47259259259259	OLR1/FOS	1.90089582411319
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/25	45/9376	8.33422222222222	HLA-A	2.54989819124068
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/25	46/9376	8.15304347826087	FTH1	2.51452277081848
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/25	224/9376	3.34857142857143	FOS/HLA-A	1.83948559265727
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/25	226/9376	3.31893805309734	CGA/FOS	1.82456539561984
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/25	49/9376	7.65387755102041	FOSB	2.41450700715895
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/25	50/9376	7.5008	SAT1	2.38303661698354
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/25	57/9376	6.57964912280702	ACADVL	2.18467216384185
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/25	59/9376	6.35661016949153	CGA	2.13405011316653
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/25	59/9376	6.35661016949153	GADD45G	2.13405011316653
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/25	61/9376	6.14819672131148	FTH1	2.08571630197997
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/25	63/9376	5.95301587301587	GADD45G	2.03949106522241
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/25	66/9376	5.68242424242424	CYP19A1	1.97376071602554
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/25	70/9376	5.35771428571429	LEP	1.89213823708303
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/25	70/9376	5.35771428571429	HLA-A	1.89213823708303
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/25	73/9376	5.13753424657534	GADD45G	1.83492422818627
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/25	73/9376	5.13753424657534	GADD45G	1.83492422818627
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/25	75/9376	5.00053333333333	GADD45G	1.79849948148207
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/25	75/9376	5.00053333333333	CGA	1.79849948148207
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/25	76/9376	4.93473684210526	GADD45G	1.7807691676559
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/25	77/9376	4.87064935064935	GADD45G	1.76334659004059
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/25	77/9376	4.87064935064935	GADD45G	1.76334659004059
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/25	78/9376	4.80820512820513	FOS	1.74622209068708
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/25	78/9376	4.80820512820513	FOS	1.74622209068708
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/25	82/9376	4.57365853658537	HLA-A	1.68052609075257
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/25	90/9376	4.16711111111111	FOS	1.56097816792067
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/25	91/9376	4.12131868131868	FOS	1.54701479744572
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/25	93/9376	4.03268817204301	FOS	1.51967832961624
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/25	93/9376	4.03268817204301	CGA	1.51967832961624
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/25	93/9376	4.03268817204301	GADD45G	1.51967832961624
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/25	97/9376	3.86639175257732	FOS	1.46722743604499
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/25	99/9376	3.78828282828283	FOS	1.44203983382665
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/25	99/9376	3.78828282828283	FOS	1.44203983382665
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/25	103/9376	3.64116504854369	FOS	1.39357593456432
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/25	105/9376	3.57180952380952	GADD45G	1.37024041648173
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/25	105/9376	3.57180952380952	CLEC4E	1.37024041648173
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/25	109/9376	3.44073394495413	FOS	1.3252283644873
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/25	109/9376	3.44073394495413	FOS	1.3252283644873
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/25	110/9376	3.40945454545455	FLT1	1.31430314280654
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/25	110/9376	3.40945454545455	INHBA	1.31430314280654
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/25	110/9376	3.40945454545455	SPDYE2	1.31430314280654
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/25	115/9376	3.26121739130435	FOS	1.26150480519664
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/25	115/9376	3.26121739130435	DUSP1	1.26150480519664
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/25	115/9376	3.26121739130435	FOS	1.26150480519664
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/25	119/9376	3.15159663865546	FOS	1.22130973822729
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/25	122/9376	3.07409836065574	LEP	1.19226042905789
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/25	122/9376	3.07409836065574	FOS	1.19226042905789
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/25	130/9376	2.88492307692308	FOS	1.11896106991584
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/25	133/9376	2.81984962406015	GADD45G	1.09290260541774
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/25	133/9376	2.81984962406015	HLA-A	1.09290260541774
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/25	133/9376	2.81984962406015	FOS	1.09290260541774
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/25	136/9376	2.75764705882353	FOS	1.0675586759746
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/25	138/9376	2.71768115942029	SPDYE2	1.05104117576241
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/25	138/9376	2.71768115942029	FOS	1.05104117576241
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/25	139/9376	2.69812949640288	FOS	1.04289202895592
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/25	144/9376	2.60444444444444	INHBA	1.00319335310141
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/25	144/9376	2.60444444444444	ACADVL	1.00319335310141
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/25	150/9376	2.50026666666667	GADD45G	0.957709903784772
NA	NA	hsa04518	Integrin signaling	1/25	154/9376	2.43532467532468	FLT1	0.928591206252586
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/25	158/9376	2.37367088607595	GADD45G	0.900366855789544
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/25	160/9376	2.344	HLA-A	0.886573285865019
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/25	163/9376	2.30085889570552	FOS	0.866263611731814
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/25	166/9376	2.25927710843374	RGS2	0.846393172900125
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/25	168/9376	2.23238095238095	FTH1	0.833380965394306
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/25	170/9376	2.20611764705882	GADD45G	0.820550399471961
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/25	173/9376	2.1678612716763	TMPRSS4	0.801634152269263
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/25	174/9376	2.15540229885057	PPP1R15A	0.795414220379465
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/25	180/9376	2.08355555555556	HLA-A	0.758952452088892
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/25	181/9376	2.07204419889503	CLEC4E	0.753013436684124
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/25	191/9376	1.96356020942408	FOSB	0.695636841744191
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/25	200/9376	1.8752	FOS	0.646877757452282
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/25	203/9376	1.84748768472906	FLT1	0.631178696555343
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/25	205/9376	1.82946341463415	HLA-A	0.620858216629675
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/25	212/9376	1.76905660377358	FLT1	0.585612461889413
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/25	217/9376	1.72829493087558	FOS	0.561228527902168
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/25	227/9376	1.65215859030837	HLA-A	0.514287475545745
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/25	227/9376	1.65215859030837	FOS	0.514287475545745
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/25	238/9376	1.57579831932773	FLT1	0.465221640719658
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/25	238/9376	1.57579831932773	FOS	0.465221640719658
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/25	248/9376	1.51225806451613	FOS	0.422720629823357
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/25	250/9376	1.50016	SLC11A1	0.414443509357129
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/25	250/9376	1.50016	HLA-A	0.414443509357129
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/25	254/9376	1.47653543307087	FLT1	0.398101337596972
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/25	268/9376	1.39940298507463	DUSP1	0.342999752348792
NA	NA	hsa04517	IgSF CAM signaling	1/25	299/9376	1.2543143812709	CABLES1	0.231079787953308
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/25	323/9376	1.16111455108359	MCL1	0.15235839204716
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	1/25	333/9376	1.12624624624625	HLA-A	0.12128607426347
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/25	449/9376	0.835278396436526	RGS2	-0.184947122458848