category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	4/28	52/9376	25.7582417582418	CGA/CYP19A1/HSD3B1/CYP11A1	9.79773391530438
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	7/28	298/9376	7.86577181208054	CSH1/LEP/GDF15/CSH2/EBI3/GH2/INHBA	6.59185597837752
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	5/28	168/9376	9.96598639455782	CSH1/LEP/CSH2/GH2/EGFR	6.41764017063322
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	6/28	300/9376	6.69714285714286	GADD45G/FLT1/EGFR/FOS/HSPB1/NTRK2	5.48877964042944
NA	NA	hsa04081	Hormone signaling	5/28	219/9376	7.64514024787997	CGA/CSH1/LEP/CSH2/GH2	5.44571493386042
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	4/28	122/9376	10.9789227166276	CSH1/CSH2/GH2/FOS	6.07161365389871
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	6/28	362/9376	5.55011838989739	CSH1/CSH2/GH2/FLT1/EGFR/NTRK2	4.83196196609877
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	6/28	370/9376	5.43011583011583	CGA/CSH1/KISS1/LEP/CSH2/GH2	4.75833784737683
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/28	139/9376	9.63617677286742	KRT19/EGFR/FOS/KRT23	5.61395275698021
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	3/28	66/9376	15.2207792207792	CYP19A1/HSD3B1/CYP11A1	6.34491521731707
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/28	87/9376	11.5467980295567	GADD45G/EGFR/FOS	5.4088019096563
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/28	148/9376	6.78764478764479	GADD45G/EGFR/FOS	3.88404484448302
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	3/28	155/9376	6.48110599078341	HSD3B1/EGFR/CYP11A1	3.76574007725743
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/28	59/9376	11.3510895883777	GADD45G/EGFR	4.36495054493249
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/28	65/9376	10.3032967032967	HSD3B1/CYP11A1	4.11908438186264
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/28	65/9376	10.3032967032967	CGA/KISS1	4.11908438186264
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/28	71/9376	9.43259557344065	CGA/FOS	3.90335058433635
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/28	73/9376	9.17416829745597	GADD45G/EGFR	3.83706182376192
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	2/28	73/9376	9.17416829745597	GADD45G/EGFR	3.83706182376192
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/28	76/9376	8.81203007518797	GADD45G/EGFR	3.74226493652571
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/28	77/9376	8.69758812615956	GADD45G/EGFR	3.71182258869933
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/28	90/9376	7.44126984126984	EGFR/FOS	3.36034378112734
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/28	93/9376	7.20122887864823	EGFR/NECTIN4	3.28912487251697
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/28	93/9376	7.20122887864823	CGA/EGFR	3.28912487251697
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/28	95/9376	7.04962406015038	FLT1/FOS	3.24338202568132
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	3/28	238/9376	4.22088835534214	FLT1/EGFR/NTRK2	2.75450696553279
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/28	98/9376	6.83381924198251	HSD3B1/CYP11A1	3.17719685774417
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/28	99/9376	6.76479076479077	EGFR/FOS	3.15575057522332
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/28	99/9376	6.76479076479077	KRT19/KRT23	3.15575057522332
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/28	99/9376	6.76479076479077	EGFR/FOS	3.15575057522332
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	1/28	12/9376	27.9047619047619	NECTIN4	5.10380855585106
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/28	254/9376	3.95500562429696	FLT1/EGFR/NTRK2	2.61297610470541
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/28	109/9376	6.14416775884666	EBI3/FOS	2.95640611976089
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/28	110/9376	6.08831168831169	FLT1/EGFR	2.937847194159
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/28	115/9376	5.82360248447205	EGFR/FOS	2.84837254002192
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/28	130/9376	5.15164835164835	EGFR/FOS	2.60867871628675
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/28	133/9376	5.03544575725027	GADD45G/EGFR	2.56517004674582
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/28	137/9376	4.88842544316997	GADD45G/FOS	2.50915146453997
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/28	150/9376	4.4647619047619	GADD45G/EGFR	2.34108726259917
NA	NA	hsa04518	Integrin signaling	2/28	154/9376	4.34879406307978	FLT1/EGFR	2.29319794829074
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/28	154/9376	4.34879406307978	EGFR/FOS	2.29319794829074
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/28	157/9376	4.26569608735214	LEP/FOS	2.25833823075742
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/28	170/9376	3.93949579831933	GADD45G/EGFR	2.11673807203473
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/28	174/9376	3.84893267651888	MAN1C1/DERL3	2.07596964140938
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/28	37/9376	9.05019305019305	GADD45G	2.68511117208798
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/28	41/9376	8.16724738675958	EGFR	2.51705360205387
NA	NA	hsa04519	Cadherin signaling	3/28	404/9376	2.48656294200849	KRT19/EGFR/KRT23	1.67160882143562
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/28	42/9376	7.97278911564626	KMO	2.47857793735949
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/28	42/9376	7.97278911564626	SAT1	2.47857793735949
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/28	201/9376	3.3319118692253	GADD45G/FLT1	1.82899461668235
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/28	203/9376	3.2990851513019	FLT1/EGFR	1.81239427126045
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/28	44/9376	7.61038961038961	MAN1C1	2.40531152588794
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/28	212/9376	3.15902964959569	FLT1/EGFR	1.7401604692618
NA	NA	hsa03272	Virion - Hepatitis viruses	1/28	48/9376	6.97619047619048	EGFR	2.27172670353093
NA	NA	hsa04382	Cornified envelope formation	2/28	217/9376	3.0862409479921	KRT19/KRT23	1.70167102786167
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/28	217/9376	3.0862409479921	EGFR/FOS	1.70167102786167
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/28	50/9376	6.69714285714286	SAT1	2.21054677127425
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/28	226/9376	2.96333754740834	CGA/FOS	1.63509860035749
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	2/28	227/9376	2.95028319697923	EGFR/FOS	1.62790514530706
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/28	54/9376	6.2010582010582	CGA	2.09768052537555
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/28	56/9376	5.97959183673469	MAN1C1	2.04543228075362
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/28	238/9376	2.81392557022809	EGFR/FOS	1.55127097462544
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/28	59/9376	5.67554479418886	CGA	1.9716302929274
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/28	60/9376	5.58095238095238	HSPB1	1.94814807897987
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/28	63/9376	5.31519274376417	GADD45G	1.88074958248028
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/28	69/9376	4.85300207039337	FOS	1.75802170547438
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/28	70/9376	4.78367346938776	LEP	1.7389474084772
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/28	71/9376	4.71629778672032	EGFR	1.72023109741571
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/28	71/9376	4.71629778672032	EGFR	1.72023109741571
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/28	75/9376	4.4647619047619	GADD45G	1.64871089244615
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/28	75/9376	4.4647619047619	CGA	1.64871089244615
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/28	77/9376	4.34879406307978	GADD45G	1.61480833275543
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/28	78/9376	4.29304029304029	FOS	1.59828740511199
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/28	78/9376	4.29304029304029	FOS	1.59828740511199
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/28	80/9376	4.18571428571429	EGFR	1.56606239430163
NA	NA	hsa04517	IgSF CAM signaling	2/28	299/9376	2.23984710941233	GRIP1/NECTIN4	1.192443641973
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/28	86/9376	3.8936877076412	EGFR	1.47536110533316
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/28	89/9376	3.76243980738363	EGFR	1.43303040891746
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/28	91/9376	3.67974882260597	FOS	1.40581810753078
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/28	93/9376	3.60061443932412	FOS	1.37936299459282
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/28	93/9376	3.60061443932412	GADD45G	1.37936299459282
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/28	94/9376	3.56231003039514	FOS	1.36640714232304
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/28	97/9376	3.45213549337261	FOS	1.32857184707759
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/28	103/9376	3.25104022191401	FOS	1.25717877321286
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/28	103/9376	3.25104022191401	HSPB1	1.25717877321286
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/28	105/9376	3.1891156462585	GADD45G	1.23454056871824
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/28	106/9376	3.15902964959569	EGFR	1.22342393860992
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/28	109/9376	3.07208387942333	FOS	1.19084791728458
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/28	110/9376	3.04415584415584	INHBA	1.18023774466725
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/28	115/9376	2.91180124223602	FOS	1.12893261372489
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/28	119/9376	2.81392557022809	FOS	1.08984092890364
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/28	120/9376	2.79047619047619	NTRK2	1.08032096014442
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/28	122/9376	2.74473067915691	LEP	1.0615705637537
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/28	122/9376	2.74473067915691	FOS	1.0615705637537
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/28	133/9376	2.51772287862513	FOS	0.964755197245632
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/28	136/9376	2.46218487394958	FOS	0.940028579300301
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/28	138/9376	2.42650103519669	FOS	0.923906361468261
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/28	142/9376	2.35814889336016	RHOBTB1	0.892487049962632
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/28	142/9376	2.35814889336016	FOS	0.892487049962632
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/28	142/9376	2.35814889336016	FOS	0.892487049962632
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/28	144/9376	2.32539682539683	INHBA	0.877171628297885
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/28	149/9376	2.24736337488015	EGFR	0.839964949645983
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/28	154/9376	2.17439703153989	KMO	0.804207369123566
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/28	156/9376	2.14652014652015	EGFR	0.790285167910002
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/28	157/9376	2.13284804367607	GADD45G	0.783402367593478
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/28	158/9376	2.11934900542495	GADD45G	0.776570719157807
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/28	163/9376	2.05433829973707	FOS	0.74315354113772
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/28	184/9376	1.81987577639752	SEMA3B	0.614691575218536
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/28	191/9376	1.75317875841436	NTRK2	0.575546568071149
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/28	196/9376	1.70845481049563	FOS	0.548560017919349
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/28	200/9376	1.67428571428571	FOS	0.527518331323847
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	1/28	204/9376	1.64145658263305	EGFR	0.506938912602027
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/28	205/9376	1.63344947735192	GADD45G	0.50186379688592
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/28	214/9376	1.56475300400534	FOS	0.457378340741834
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/28	216/9376	1.55026455026455	FOS	0.447771013314861
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/28	224/9376	1.49489795918367	FOS	0.410286255427271
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/28	227/9376	1.47514159848962	EGFR	0.396601608488812
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/28	232/9376	1.44334975369458	EGFR	0.374220571164149
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/28	248/9376	1.35023041474654	FOS	0.305912473192264
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/28	250/9376	1.33942857142857	EGFR	0.29770317774728
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/28	253/9376	1.32354601919819	EGFR	0.285517535287989
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/28	323/9376	1.03670942061035	EGFR	0.0367441185006352
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	1/28	333/9376	1.00557700557701	EGFR	0.00567116433476766