category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
NA	NA	hsa04081	Hormone signaling	9/79	219/9376	4.87740593029305	CGA/LEP/CSH1/CSH2/GH2/CRH/GNG11/RAMP2/GUCA2A	5.35198008699021
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	4/79	52/9376	9.12950340798442	CGA/CYP11A1/HSD3B1/CYP19A1	5.41866528585651
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	6/79	142/9376	5.01479764663933	FOS/DUSP1/SDC1/CALM1/ACTG1/GSTP1	4.44365840596299
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	6/79	168/9376	4.23869801084991	LEP/CSH1/CSH2/GH2/CSF2RB/FHL1	3.90454298621809
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	9/79	362/9376	2.95069585285684	CSH1/CSH2/FLT1/GH2/GNG11/AREG/ITGA5/SGK1/PGF	3.4890953453712
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	8/79	298/9376	3.18613541755161	LEP/CSH1/EBI3/CSH2/GDF15/GH2/INHBA/CSF2RB	3.53523160771224
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	5/79	122/9376	4.86407968458186	CSH1/CSH2/FOS/GH2/JUNB	3.95994368616343
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	9/79	370/9376	2.88689702360588	CGA/LEP/CSH1/KISS1/CSH2/GH2/CRH/ADM/APLNR	3.41358607709048
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	2/79	12/9376	19.7805907172996	NECTIN4/FCGR2B	6.00063121919774
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	5/79	134/9376	4.42849045909692	MYL6/CALM1/PLA2G2A/RAMP2/ADM	3.68468300031181
NA	NA	hsa04382	Cornified envelope formation	6/79	217/9376	3.28157265356122	KRT19/KRT8/S100A6/S100A11/S100A9/KRT10	3.13449736165055
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	7/79	300/9376	2.76928270042194	GADD45G/HSPB1/FOS/FLT1/DUSP1/AREG/PGF	2.87103431472274
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	4/79	110/9376	4.31576524741082	FLT1/SERPINE1/EPAS1/SLC2A1	3.22449522686158
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	3/79	66/9376	5.39470655926352	CYP11A1/HSD3B1/CYP19A1	3.30259088224707
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	6/79	268/9376	2.65709427545815	DUSP1/CALM1/MT-CYB/COX7A2/UBC/HSPA5	2.53706077853279
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	3/79	76/9376	4.68487674883411	PLIN2/FABP4/UBC	2.97314476883226
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/79	78/9376	4.56475170399221	FOS/CALM1/ITGA5	2.91413444358915
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/79	137/9376	3.46521297237365	GADD45G/FOS/CSF2RB/ACTG1	2.67935348048476
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/79	139/9376	3.41535379291504	KRT19/FOS/CALM1/KRT10	2.64454188827621
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	4/79	140/9376	3.39095840867993	SERPINE1/GNG11/CALM1/APLNR	2.62737368361053
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	5/79	212/9376	2.79914019584428	FLT1/CALM1/PFN1/PGF/ACTG1	2.44240772615926
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/79	87/9376	4.09253601047577	GADD45G/FOS/AREG	2.67126933478712
NA	NA	hsa04518	Integrin signaling	4/79	154/9376	3.0826894624363	FLT1/ITGA5/PGF/ACTG1	2.40214981470222
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/79	154/9376	3.0826894624363	FOS/MYL6/CALM1/ACTG1	2.40214981470222
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	4/79	155/9376	3.06280114332381	FCGR2B/ITGA5/ATP6V1F/ACTG1	2.38705249479128
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/79	157/9376	3.02378456824962	LEP/FOS/MT-CYB/COX7A2	2.35721918501419
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/79	95/9376	3.74790139906729	FOS/FLT1/ATP6V1F	2.48138029934363
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	5/79	233/9376	2.54685717390123	SDC1/BGN/ITGA5/FHL1/ACTG1	2.20399997267202
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	3/79	97/9376	3.67062508156075	FOS/GNG11/CALM1	2.4371147130526
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	3/79	98/9376	3.63316972358564	CALM1/CYP11A1/HSD3B1	2.41541898230696
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	5/79	238/9376	2.49335177108818	FLT1/GNG11/CALM1/PLA2G2A/PGF	2.15106132224207
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/79	238/9376	2.49335177108818	FOS/RPS13/RPL7/RPL41/RPL34	2.15106132224207
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/79	99/9376	3.59647103950901	KRT19/FCGR2B/KRT10	2.39400509468848
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/79	174/9376	2.72835734031718	SSR4/CRYAB/MAN1C1/HSPA5	2.12126446331744
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/79	51/9376	4.65425663936461	ATP6V1F/ACTG1	2.41205652429078
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/79	196/9376	2.42211314905709	FOS/GNG11/CALM1/UBC	1.85467840566611
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/79	59/9376	4.02317099334907	CGA/FABP4	2.14722936784103
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/79	203/9376	2.33859200598616	FLT1/ITGA5/PGF/ACTG1	1.77733100731718
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/79	204/9376	2.3271283196823	CD63/SDC1/ITGA5/ACTG1	1.76654109862774
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/79	133/9376	2.67707242790521	FOS/GNG11/CALM1	1.79555590394113
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/79	65/9376	3.65180136319377	CYP11A1/HSD3B1	1.97754908914121
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/79	65/9376	3.65180136319377	CGA/KISS1	1.97754908914121
NA	NA	hsa04517	IgSF CAM signaling	5/79	299/9376	1.98467465390966	MYL6/DYNLL1/NECTIN4/ITGA5/ACTG1	1.59508912415082
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/79	138/9376	2.58007705008255	ATP6V1F/MT-CYB/COX7A2	1.72367982258053
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	3/79	138/9376	2.58007705008255	FOS/ITGA5/ACTG1	1.72367982258053
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	2/79	69/9376	3.44010273344341	FOS/CALM1	1.87523442996153
Genetic Information Processing	Translation	hsa03010	Ribosome	4/79	222/9376	2.13844223970806	RPS13/RPL7/RPL41/RPL34	1.5823764199234
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/79	70/9376	3.39095840867993	LEP/SLC2A1	1.85083321951834
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/79	70/9376	3.39095840867993	EPAS1/SLC2A1	1.85083321951834
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/79	142/9376	2.50739882331966	FOS/JUNB/FCGR2B	1.66841919367721
Metabolism	Metabolism of cofactors and vitamins	hsa00730	Thiamine metabolism	1/79	15/9376	7.91223628691983	ALPP	2.46962407879315
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/79	71/9376	3.34319843109289	CGA/FOS	1.82687074794912
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	4/79	226/9376	2.10059370449199	CGA/FOS/CRH/CALM1	1.54382640684878
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/79	75/9376	3.16489451476793	GADD45G/SERPINE1	1.73512320493637
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/79	75/9376	3.16489451476793	CGA/HSPA5	1.73512320493637
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/79	76/9376	3.12325116588941	CALM1/ACTG1	1.71314633488852
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/79	76/9376	3.12325116588941	GADD45G/CALM1	1.71314633488852
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/79	78/9376	3.04316780266147	ITGA5/ACTG1	1.67026097809284
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/79	78/9376	3.04316780266147	FOS/EEF1A1	1.67026097809284
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	3/79	154/9376	2.31201709682722	ALPP/KMO/RDH13	1.51326526727748
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	3/79	155/9376	2.29710085749285	CRH/CYP11A1/HSD3B1	1.50099191475394
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/79	157/9376	2.26783842618721	GADD45G/SERPINE1/CALM1	1.47672489878284
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/79	157/9376	2.26783842618721	SERPINE1/AREG/ACTG1	1.47672489878284
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	2/79	82/9376	2.89472059277555	UCK2/GSTP1	1.5884682394115
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	4/79	248/9376	1.91425071457738	FOS/DYNLL1/PFN1/ACTG1	1.34502730690998
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	2/79	86/9376	2.76008242566971	ITGA5/ACTG1	1.5114790902511
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/79	253/9376	1.87641967278731	ITGA5/PFN1/ACTG1/UBC	1.30266069377209
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/79	87/9376	2.72835734031718	MT-CYB/COX7A2	1.49291970961827
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/79	88/9376	2.69735327963176	SERPINE1/TFPI	1.47462042469369
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/79	170/9376	2.09441548771407	GADD45G/ACTG1/GSTP1	1.32739132228795
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/79	89/9376	2.66704593941118	SDC1/ITGA5	1.45657421276437
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/79	91/9376	2.60842954513841	FOS/FCGR2B	1.42121424727491
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/79	93/9376	2.55233428610317	NECTIN4/ACTG1	1.38678877330455
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/79	93/9376	2.55233428610317	CGA/CALM1	1.38678877330455
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/79	94/9376	2.52518179369782	FOS/S100A9	1.36991154436149
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/79	26/9376	4.56475170399221	PLA2G2A	1.67779123864504
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	5/79	368/9376	1.6125481563016	PFN1/ACTG1/MT-CYB/COX7A2/HSPA5	1.1050393058024
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/79	99/9376	2.39764735967268	ITGA5/ACTG1	1.2886625148983
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/79	28/9376	4.23869801084991	ALPP	1.58204155474363
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/79	28/9376	4.23869801084991	ATP6V1F	1.58204155474363
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	2/79	102/9376	2.3271283196823	PLA2G2A/SLC26A3	1.24224490783938
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/79	103/9376	2.30453484085044	FOS/SERPINE1	1.22713384214208
Human Diseases	Substance dependence	hsa05034	Alcoholism	3/79	191/9376	1.86413943932666	CRH/GNG11/CALM1	1.11221487328544
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/79	29/9376	4.09253601047577	CALM1	1.53746561388889
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/79	105/9376	2.26063893911995	ITGA5/ACTG1	1.19742920154755
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/79	194/9376	1.83531254078037	MYL6/DYNLL1/ACTG1	1.08369979385509
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/79	30/9376	3.95611814345992	PLA2G2A	1.49484889365203
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/79	107/9376	2.21838400567846	CALM1/SLC2A1	1.16838885396507
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/79	31/9376	3.82850142915476	HSPA5	1.45403668878212
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/79	109/9376	2.17767971199628	EBI3/FOS	1.13998366762831
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/79	200/9376	1.78025316455696	FOS/ACTG1/BAIAP2L1	1.02813845341989
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	3/79	205/9376	1.73683235566533	MT-CYB/COX7A2/SLC2A1	0.983252457291387
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/79	115/9376	2.06406164006604	FOS/GNG11	1.05831398080489
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/79	115/9376	2.06406164006604	GNG11/DUSP1	1.05831398080489
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/79	115/9376	2.06406164006604	FOS/SGK1	1.05831398080489
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/79	35/9376	3.39095840867993	TPI1	1.30628255199797
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/79	119/9376	1.99468141687055	FOS/JUNB	1.0065842286582
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/79	37/9376	3.20766335956209	GADD45G	1.24025587361183
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/79	214/9376	1.66378800425884	FOS/GNG11/CALM1	0.905459252686265
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	3/79	216/9376	1.64838255977496	FOS/CALM1/HSPA5	0.888665319038353
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/79	122/9376	1.94563187383275	ACTG1/SLC2A1	0.969092066905469
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/79	38/9376	3.12325116588941	SGK1	1.20891009203689
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/79	227/9376	1.56850499079909	FOS/MT-CYB/COX7A2	0.799260158474622
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/79	130/9376	1.82590068159688	FOS/GNG11	0.874078271792807
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/79	42/9376	2.82579867389994	KMO	1.09312896625577
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/79	42/9376	2.82579867389994	SAT1	1.09312896625577
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/79	43/9376	2.76008242566971	PLA2G2A	1.06631217952636
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/79	133/9376	1.7847149519368	GADD45G/SGK1	0.840154272061439
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	3/79	232/9376	1.53470100392842	ITGA5/PFN1/ACTG1	0.760176870866265
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/79	44/9376	2.69735327963176	MAN1C1	1.04025302030886
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/79	44/9376	2.69735327963176	DYNLL1	1.04025302030886
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	3/79	235/9376	1.51510907621869	ACTG1/MT-CYB/COX7A2	0.737163879997852
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/79	136/9376	1.74534623976173	FOS/FCGR2B	0.807085048141944
NA	NA	hsa03272	Virion - Hepatitis viruses	1/79	48/9376	2.47257383966245	CD63	0.942825237746671
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/79	142/9376	1.67159921554644	RHOBTB1/UBC	0.743339456248616
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/79	50/9376	2.37367088607595	SAT1	0.89773417608777
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/79	50/9376	2.37367088607595	SDC1	0.89773417608777
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/79	51/9376	2.3271283196823	PLA2G2A	0.875994446470339
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/79	148/9376	1.60383167978105	GADD45G/FOS	0.682528400671218
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/79	54/9376	2.19784341303329	CGA	0.813710926995704
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/79	56/9376	2.11934900542495	MAN1C1	0.774424962516213
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/79	56/9376	2.11934900542495	EEF1A1	0.774424962516213
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/79	480/9376	1.23628691983122	CALM1/MT-CYB/COX7A2/UBC/HSPA5	0.489881096136993
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/79	157/9376	1.51189228412481	SGK1/SLC2A1	0.596230612551496
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	2/79	158/9376	1.50232334561769	SGK1/ATP6V1F	0.586977322036568
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/79	59/9376	2.01158549667453	UCK2	0.71848601727134
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/79	59/9376	2.01158549667453	GSTP1	0.71848601727134
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/79	59/9376	2.01158549667453	GADD45G	0.71848601727134
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/79	60/9376	1.97805907172996	HSPB1	0.700573554266518
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/79	60/9376	1.97805907172996	CRH	0.700573554266518
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/79	61/9376	1.94563187383275	SLC26A3	0.683004175211293
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/79	62/9376	1.91425071457738	CRYAB	0.665764761912276
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	3/79	275/9376	1.29472957422325	MT-CYB/COX7A2/HSPA5	0.457270595033915
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/79	63/9376	1.88386578259996	PLA2G2A	0.648842909178127
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/79	63/9376	1.88386578259996	GADD45G	0.648842909178127
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/79	170/9376	1.39627699180938	MYL6/ACTG1	0.480635230454242
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/79	67/9376	1.77139618363877	TPI1	0.584105291362262
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/79	67/9376	1.77139618363877	CALM1	0.584105291362262
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/79	68/9376	1.74534623976173	RDH13	0.568606869502264
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/79	69/9376	1.7200513667217	CALM1	0.553364043124502
NA	NA	hsa04519	Cadherin signaling	4/79	404/9376	1.1750845970673	KRT19/KRT8/KRT10/ACTG1	0.331605526244636
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/79	70/9376	1.69547920433996	GSTP1	0.538368216780178
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/79	70/9376	1.69547920433996	ACTG1	0.538368216780178
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/79	71/9376	1.67159921554644	ATP6V1F	0.523611208059374
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/79	71/9376	1.67159921554644	SLC2A1	0.523611208059374
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/79	181/9376	1.31142037904749	CALM1/FCGR2B	0.38997630314445
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/79	73/9376	1.62580197676435	GSTP1	0.494782828069022
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/79	73/9376	1.62580197676435	GADD45G	0.494782828069022
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/79	73/9376	1.62580197676435	GADD45G	0.494782828069022
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/79	75/9376	1.58244725738397	TPI1	0.466820782742294
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/79	75/9376	1.58244725738397	GSTP1	0.466820782742294
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/79	77/9376	1.54134473121815	GADD45G	0.439672113775246
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/79	77/9376	1.54134473121815	GADD45G	0.439672113775246
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	3/79	308/9376	1.15600854841361	TGM2/MT-CYB/COX7A2	0.256623111767954
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/79	78/9376	1.52158390133074	TPI1	0.426387512596537
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/79	79/9376	1.50232334561769	GSTP1	0.413288443065214
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/79	79/9376	1.50232334561769	ATP6V1F	0.413288443065214
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/79	82/9376	1.44736029638777	HSPA5	0.375051406046482
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/79	83/9376	1.42992222052768	PRDX5	0.362642531868683
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/79	201/9376	1.18093078909251	GADD45G/FLT1	0.239020548071011
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/79	85/9376	1.39627699180938	UCK2	0.338302228580653
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/79	86/9376	1.38004121283485	AREG	0.326362185234014
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/79	86/9376	1.38004121283485	SLC2A1	0.326362185234014
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/79	89/9376	1.33352296970559	GNG11	0.291414258931188
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/79	90/9376	1.31870604781997	SLC2A1	0.280043172020933
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/79	90/9376	1.31870604781997	FOS	0.280043172020933
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/79	91/9376	1.3042147725692	GNG11	0.268805289180164
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/79	93/9376	1.27616714305159	FOS	0.24671586330863
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/79	93/9376	1.27616714305159	CALM1	0.24671586330863
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/79	93/9376	1.27616714305159	GADD45G	0.24671586330863
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/79	98/9376	1.21105657452855	CALM1	0.19360318930097
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/79	98/9376	1.21105657452855	FCGR2B	0.19360318930097
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/79	224/9376	1.05967450271248	FOS/SLC2A1	0.0833263925619588
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/79	99/9376	1.19882367983634	FOS	0.18331993510812
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/79	99/9376	1.19882367983634	CALM1	0.18331993510812
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/79	99/9376	1.19882367983634	FOS	0.18331993510812
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/79	100/9376	1.18683544303797	ITGA5	0.173143688290252
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/79	227/9376	1.04566999386606	GNG11/CALM1	0.0642073633929097
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/79	101/9376	1.1750845970673	CALM1	0.163072014834486
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/79	101/9376	1.1750845970673	SERPINE1	0.163072014834486
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/79	103/9376	1.15226742042522	HSPB1	0.143233050439382
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/79	104/9376	1.14118792599805	PLA2G2A	0.133461279818734
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/79	105/9376	1.13031946955998	GADD45G	0.123785116847365
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/79	105/9376	1.13031946955998	UBC	0.123785116847365
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/79	105/9376	1.13031946955998	CALM1	0.123785116847365
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/79	106/9376	1.11965607833771	GSTP1	0.114202496784968
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/79	108/9376	1.09892170651664	EEF1A1	0.0953099481750283
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/79	109/9376	1.08883985599814	FOS	0.0859962040958149
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/79	109/9376	1.08883985599814	SLC2A1	0.0859962040958149
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/79	110/9376	1.0789413118527	INHBA	0.0767683669614439
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/79	250/9376	0.94946835443038	CD63/ATP6V1F	-0.0746484822011337
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/79	116/9376	1.02313400261894	TPI1	0.0231101119902321
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/79	116/9376	1.02313400261894	ACTG1	0.0231101119902321
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/79	116/9376	1.02313400261894	GNG11	0.0231101119902321
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/79	117/9376	1.01438926755382	ACTG1	0.0144370129195497
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/79	254/9376	0.934516096880295	FLT1/CALM1	-0.0975290850612728
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/79	120/9376	0.989029535864979	CALM1	-0.0111488923063997
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	3/79	388/9376	0.917656270390187	CALM1/MT-CYB/COX7A2	-0.152701264347839
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/79	122/9376	0.972815936916373	LEP	-0.0278584728471837
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/79	122/9376	0.972815936916373	FOS	-0.0278584728471837
Organismal Systems	Immune system	hsa04611	Platelet activation	1/79	126/9376	0.94193289129998	ACTG1	-0.060488438940473
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/79	138/9376	0.860025683360851	CALM1	-0.152695658264129
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/79	138/9376	0.860025683360851	CALM1	-0.152695658264129
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/79	144/9376	0.824191279887482	INHBA	-0.195975386119215
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/79	149/9376	0.796533854387902	GNG11	-0.230771833361053
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/79	150/9376	0.791223628691983	GADD45G	-0.237600865173727
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/79	154/9376	0.770672365609074	CALM1	-0.264503827571994
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/79	158/9376	0.751161672808845	GADD45G	-0.290773773882868
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/79	160/9376	0.741772151898734	SDC1	-0.303682385876664
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/79	163/9376	0.728119903704279	FOS	-0.322773929962637
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/79	166/9376	0.71496111026384	CALM1	-0.341551435529027
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/79	169/9376	0.702269492921878	UBC	-0.360027260762315
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/79	173/9376	0.686032047998829	ACTG1	-0.384212445949013
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/79	333/9376	0.712814079902688	ITGA5/ATP6V1F	-0.491877280886088
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/79	180/9376	0.659353023909986	ITGA5	-0.425372174841026
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/79	184/9376	0.645019262520638	SEMA3B	-0.448266680751442
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/79	193/9376	0.614940644061127	GNG11	-0.498243694014555
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/79	195/9376	0.608633560532295	ACTG1	-0.509077217351807
NA	NA	hsa04082	Neuroactive ligand signaling	1/79	199/9376	0.596399720119585	GNG11	-0.530463369318083
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/79	205/9376	0.57894411855511	GADD45G	-0.561870318132068
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/79	217/9376	0.546928775593537	FOS	-0.622443714569064
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/79	323/9376	0.367441313634048	ITGA5	-1.06643304344885
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/79	449/9376	0.264328606467255	CALM1	-1.47259065582614