ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005179 hormone activity 12/123 132/18639 0.0909090909090909 13.7760532150776 7.07529084866824e-11 3.006998610684e-08 GO:0051427 hormone receptor binding 6/123 34/18639 0.176470588235294 26.7417503586801 8.44500920277137e-08 1.79456445558892e-05 GO:0008083 growth factor activity 8/123 162/18639 0.0493827160493827 7.48328816621499 1.2096364952146e-05 0.00171365170155401 GO:0005131 growth hormone receptor binding 3/123 10/18639 0.3 45.4609756097561 3.25333634707999e-05 0.00345666986877249 GO:0048306 calcium-dependent protein binding 5/123 80/18639 0.0625 9.47103658536585 0.000186723142652053 0.0158714671254245 GO:0005154 epidermal growth factor receptor binding 3/123 35/18639 0.0857142857142857 12.988850174216 0.00157319108584797 0.111434368580898 GO:0048185 activin binding 2/123 11/18639 0.181818181818182 27.5521064301552 0.00228499602729621 0.124313224503668 GO:0005126 cytokine receptor binding 7/123 275/18639 0.0254545454545455 3.85729490022173 0.0023400136377161 0.124313224503668 GO:0010853 cyclase activator activity 2/123 12/18639 0.166666666666667 25.2560975609756 0.00273018103004573 0.128925215307715 GO:0005172 vascular endothelial growth factor receptor binding 2/123 13/18639 0.153846153846154 23.313320825516 0.00321268259878802 0.132174892076839 GO:0005504 fatty acid binding 3/123 47/18639 0.0638297872340425 9.67254800207576 0.00367987313856245 0.132174892076839 GO:0044548 S100 protein binding 2/123 14/18639 0.142857142857143 21.6480836236934 0.00373199695275779 0.132174892076839 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/123 16/18639 0.125 18.9420731707317 0.00487907349993221 0.145621014534182 GO:0005246 calcium channel regulator activity 3/123 53/18639 0.0566037735849057 8.57754256787851 0.00516618495378483 0.145621014534182 GO:0016860 intramolecular oxidoreductase activity 3/123 53/18639 0.0566037735849057 8.57754256787851 0.00516618495378483 0.145621014534182 GO:0036041 long-chain fatty acid binding 2/123 17/18639 0.117647058823529 17.8278335724534 0.00550585261177884 0.145621014534182 GO:0070064 proline-rich region binding 2/123 18/18639 0.111111111111111 16.8373983739837 0.00616747826262418 0.145621014534182 GO:0098641 cadherin binding involved in cell-cell adhesion 2/123 18/18639 0.111111111111111 16.8373983739837 0.00616747826262418 0.145621014534182 GO:0045296 cadherin binding 7/123 334/18639 0.0209580838323353 3.1759164597634 0.00673634585318875 0.145848756653309 GO:0015245 fatty acid transmembrane transporter activity 2/123 19/18639 0.105263157894737 15.9512195121951 0.0068634709013322 0.145848756653309 GO:0010851 cyclase regulator activity 2/123 20/18639 0.1 15.1536585365854 0.00759335569858048 0.147592185680848 GO:0015026 coreceptor activity 3/123 61/18639 0.0491803278688525 7.45261895241903 0.00764006608230272 0.147592185680848 GO:0051428 peptide hormone receptor binding 2/123 21/18639 0.0952380952380952 14.4320557491289 0.00835666250625565 0.15014894342268 GO:0051082 unfolded protein binding 4/123 121/18639 0.0330578512396694 5.00947389639186 0.00847899915798666 0.15014894342268 GO:0048027 mRNA 5'-UTR binding 2/123 24/18639 0.0833333333333333 12.6280487804878 0.010842482885186 0.184322209048162 GO:0019207 kinase regulator activity 6/123 287/18639 0.0209059233449477 3.16801223761367 0.0120048487715611 0.196233104919748 GO:0070851 growth factor receptor binding 4/123 139/18639 0.0287769784172662 4.36076504649939 0.0135833865104096 0.206620079851989 GO:0008395 steroid hydroxylase activity 2/123 27/18639 0.0740740740740741 11.2249322493225 0.0136126170255428 0.206620079851989 GO:0033293 monocarboxylic acid binding 3/123 79/18639 0.0379746835443038 5.75455387465267 0.0154125694141266 0.225873862103579 GO:0016209 antioxidant activity 3/123 86/18639 0.0348837209302326 5.2861599546228 0.0192969301129798 0.268050553782027 GO:0005125 cytokine activity 5/123 234/18639 0.0213675213675214 3.2379612257661 0.0195519227464537 0.268050553782027 GO:0004857 enzyme inhibitor activity 7/123 416/18639 0.0168269230769231 2.54989446529081 0.0204696888288339 0.27186305475795 GO:0015035 protein-disulfide reductase activity 2/123 34/18639 0.0588235294117647 8.91391678622669 0.0211154110299945 0.271940899628717 GO:0004866 endopeptidase inhibitor activity 4/123 161/18639 0.0248447204968944 3.76488410846841 0.0220433851807613 0.275542314759516 GO:0033218 amide binding 5/123 247/18639 0.0202429149797571 3.06754221388368 0.0240230423160888 0.291708370981078 GO:0004867 serine-type endopeptidase inhibitor activity 3/123 95/18639 0.0315789473684211 4.78536585365854 0.0250147818558868 0.295313396909774 GO:0030414 peptidase inhibitor activity 4/123 169/18639 0.0236686390532544 3.58666474238707 0.0257665100037534 0.295966668962032 GO:0015036 disulfide oxidoreductase activity 2/123 40/18639 0.05 7.57682926829268 0.0286172962830122 0.298462678313103 GO:0071855 neuropeptide receptor binding 2/123 40/18639 0.05 7.57682926829268 0.0286172962830122 0.298462678313103 GO:0071949 FAD binding 2/123 40/18639 0.05 7.57682926829268 0.0286172962830122 0.298462678313103 GO:0003735 structural constituent of ribosome 4/123 175/18639 0.0228571428571429 3.46369337979094 0.0287928701431464 0.298462678313103 GO:0008307 structural constituent of muscle 2/123 42/18639 0.0476190476190476 7.21602787456446 0.031321615656651 0.311039783660149 GO:0016853 isomerase activity 4/123 180/18639 0.0222222222222222 3.36747967479675 0.0314699075232621 0.311039783660149 GO:0004497 monooxygenase activity 3/123 106/18639 0.0283018867924528 4.28877128393925 0.0331085484213117 0.311485889294726 GO:0008237 metallopeptidase activity 4/123 184/18639 0.0217391304347826 3.29427359490986 0.0337137668413115 0.311485889294726 GO:0061135 endopeptidase regulator activity 4/123 184/18639 0.0217391304347826 3.29427359490986 0.0337137668413115 0.311485889294726 GO:0046943 carboxylic acid transmembrane transporter activity 4/123 188/18639 0.0212765957446809 3.22418266735859 0.0360489180401172 0.314648884161241 GO:0004222 metalloendopeptidase activity 3/123 110/18639 0.0272727272727273 4.13281596452328 0.0363505576412769 0.314648884161241 GO:0005342 organic acid transmembrane transporter activity 4/123 189/18639 0.0211640211640212 3.20712349980643 0.0366470048110038 0.314648884161241 GO:0030291 protein serine/threonine kinase inhibitor activity 2/123 46/18639 0.0434782608695652 6.58854718981972 0.0370175157836754 0.314648884161241 GO:0017046 peptide hormone binding 2/123 53/18639 0.0377358490566038 5.71836171191901 0.047846463445715 0.365006308017482 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/123 54/18639 0.037037037037037 5.61246612466125 0.0494773256793928 0.365006308017482 GO:0098632 cell-cell adhesion mediator activity 2/123 55/18639 0.0363636363636364 5.51042128603104 0.0511281406247604 0.365006308017482 GO:0170055 lipid transmembrane transporter activity 2/123 56/18639 0.0357142857142857 5.41202090592335 0.052798578754033 0.365006308017482 GO:0004601 peroxidase activity 2/123 57/18639 0.0350877192982456 5.31707317073171 0.0544883139563805 0.365006308017482 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/123 59/18639 0.0338983050847458 5.13683340223233 0.0579243880411737 0.365006308017482 GO:0002020 protease binding 3/123 136/18639 0.0220588235294118 3.34271879483501 0.0611762149900632 0.365006308017482 GO:0019838 growth factor binding 3/123 136/18639 0.0220588235294118 3.34271879483501 0.0611762149900632 0.365006308017482 GO:0044325 transmembrane transporter binding 3/123 136/18639 0.0220588235294118 3.34271879483501 0.0611762149900632 0.365006308017482 GO:0061134 peptidase regulator activity 4/123 226/18639 0.0176991150442478 2.68206345780272 0.0627978691033975 0.365006308017482 GO:0005522 profilin binding 1/123 10/18639 0.1 15.1536585365854 0.0640801244268342 0.365006308017482 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/123 10/18639 0.1 15.1536585365854 0.0640801244268342 0.365006308017482 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/123 10/18639 0.1 15.1536585365854 0.0640801244268342 0.365006308017482 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/123 10/18639 0.1 15.1536585365854 0.0640801244268342 0.365006308017482 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/123 10/18639 0.1 15.1536585365854 0.0640801244268342 0.365006308017482 GO:0019531 oxalate transmembrane transporter activity 1/123 10/18639 0.1 15.1536585365854 0.0640801244268342 0.365006308017482 GO:1901682 sulfur compound transmembrane transporter activity 2/123 63/18639 0.0317460317460317 4.81068524970964 0.0650141244912295 0.365006308017482 GO:0000099 sulfur amino acid transmembrane transporter activity 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0005114 type II transforming growth factor beta receptor binding 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0008271 secondary active sulfate transmembrane transporter activity 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0008432 JUN kinase binding 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0010854 adenylate cyclase regulator activity 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0015173 aromatic amino acid transmembrane transporter activity 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0019206 nucleoside kinase activity 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0019864 IgG binding 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0034713 type I transforming growth factor beta receptor binding 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0042608 T cell receptor binding 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0050786 RAGE receptor binding 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0070697 activin receptor binding 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.365006308017482 GO:0019209 kinase activator activity 3/123 148/18639 0.0202702702702703 3.07168754119974 0.0747122026204728 0.365006308017482 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/123 12/18639 0.0833333333333333 12.6280487804878 0.0763986787428554 0.365006308017482 GO:0140900 chloride:bicarbonate antiporter activity 1/123 12/18639 0.0833333333333333 12.6280487804878 0.0763986787428554 0.365006308017482 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/123 70/18639 0.0285714285714286 4.32961672473868 0.0780685601585 0.365006308017482 GO:0019855 calcium channel inhibitor activity 1/123 13/18639 0.0769230769230769 11.656660412758 0.0824975117548608 0.365006308017482 GO:0031432 titin binding 1/123 13/18639 0.0769230769230769 11.656660412758 0.0824975117548608 0.365006308017482 GO:0035325 Toll-like receptor binding 1/123 13/18639 0.0769230769230769 11.656660412758 0.0824975117548608 0.365006308017482 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/123 13/18639 0.0769230769230769 11.656660412758 0.0824975117548608 0.365006308017482 GO:0140375 immune receptor activity 3/123 156/18639 0.0192307692307692 2.91416510318949 0.0844106138410683 0.365006308017482 GO:0044183 protein folding chaperone 2/123 75/18639 0.0266666666666667 4.0409756097561 0.087851255464289 0.365006308017482 GO:0005161 platelet-derived growth factor receptor binding 1/123 14/18639 0.0714285714285714 10.8240418118467 0.088556397508869 0.365006308017482 GO:0008191 metalloendopeptidase inhibitor activity 1/123 14/18639 0.0714285714285714 10.8240418118467 0.088556397508869 0.365006308017482 GO:0019763 immunoglobulin receptor activity 1/123 14/18639 0.0714285714285714 10.8240418118467 0.088556397508869 0.365006308017482 GO:0043176 amine binding 1/123 14/18639 0.0714285714285714 10.8240418118467 0.088556397508869 0.365006308017482 GO:0019887 protein kinase regulator activity 4/123 255/18639 0.0156862745098039 2.37704447632712 0.0886357793120494 0.365006308017482 GO:0099106 ion channel regulator activity 3/123 160/18639 0.01875 2.84131097560976 0.0894523652206889 0.365006308017482 GO:0098631 cell adhesion mediator activity 2/123 76/18639 0.0263157894736842 3.98780487804878 0.0898500043764461 0.365006308017482 GO:0000774 adenyl-nucleotide exchange factor activity 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0004559 alpha-mannosidase activity 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0005523 tropomyosin binding 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0015116 sulfate transmembrane transporter activity 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0017081 chloride channel regulator activity 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0031005 filamin binding 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0031386 protein tag activity 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0033130 acetylcholine receptor binding 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0141047 molecular tag activity 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.365006308017482 GO:0016247 channel regulator activity 3/123 168/18639 0.0178571428571429 2.70601045296167 0.0999037343004508 0.365006308017482 GO:0001618 virus receptor activity 2/123 81/18639 0.0246913580246914 3.7416440831075 0.100040287925504 0.365006308017482 GO:0005159 insulin-like growth factor receptor binding 1/123 16/18639 0.0625 9.47103658536585 0.100555363663209 0.365006308017482 GO:0005521 lamin binding 1/123 16/18639 0.0625 9.47103658536585 0.100555363663209 0.365006308017482 GO:0015923 mannosidase activity 1/123 16/18639 0.0625 9.47103658536585 0.100555363663209 0.365006308017482 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/123 16/18639 0.0625 9.47103658536585 0.100555363663209 0.365006308017482 GO:0140272 exogenous protein binding 2/123 82/18639 0.024390243902439 3.69601427721594 0.102115864741291 0.365006308017482 GO:0141108 transporter regulator activity 3/123 170/18639 0.0176470588235294 2.67417503586801 0.102590629719134 0.365006308017482 GO:0008514 organic anion transmembrane transporter activity 4/123 269/18639 0.0148698884758364 2.25333212439931 0.102688791336171 0.365006308017482 GO:0001540 amyloid-beta binding 2/123 83/18639 0.0240963855421687 3.65148398471937 0.10420336518365 0.365006308017482 GO:0004860 protein kinase inhibitor activity 2/123 84/18639 0.0238095238095238 3.60801393728223 0.106302544769477 0.365006308017482 GO:0016018 cyclosporin A binding 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.365006308017482 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.365006308017482 GO:0030548 acetylcholine receptor regulator activity 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.365006308017482 GO:0038191 neuropilin binding 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.365006308017482 GO:0051787 misfolded protein binding 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.365006308017482 GO:0050660 flavin adenine dinucleotide binding 2/123 86/18639 0.0232558139534884 3.5241066364152 0.110534976712288 0.370302280544189 GO:0004252 serine-type endopeptidase activity 3/123 176/18639 0.0170454545454545 2.58300997782705 0.110821803372359 0.370302280544189 GO:0000400 four-way junction DNA binding 1/123 18/18639 0.0555555555555556 8.41869918699187 0.112397633388707 0.370302280544189 GO:0003746 translation elongation factor activity 1/123 18/18639 0.0555555555555556 8.41869918699187 0.112397633388707 0.370302280544189 GO:0099602 neurotransmitter receptor regulator activity 1/123 18/18639 0.0555555555555556 8.41869918699187 0.112397633388707 0.370302280544189 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/123 181/18639 0.0165745856353591 2.51165611103625 0.117869608350201 0.377836181076095 GO:0003756 protein disulfide isomerase activity 1/123 19/18639 0.0526315789473684 7.97560975609756 0.118260642415783 0.377836181076095 GO:0008301 DNA binding, bending 1/123 19/18639 0.0526315789473684 7.97560975609756 0.118260642415783 0.377836181076095 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/123 19/18639 0.0526315789473684 7.97560975609756 0.118260642415783 0.377836181076095 GO:0019210 kinase inhibitor activity 2/123 90/18639 0.0222222222222222 3.36747967479675 0.119129525327522 0.377836181076095 GO:0031406 carboxylic acid binding 3/123 187/18639 0.0160427807486631 2.43106821442546 0.126542283145668 0.387057444230452 GO:0016410 N-acyltransferase activity 2/123 94/18639 0.0212765957446809 3.22418266735859 0.127884778210149 0.387057444230452 GO:0042562 hormone binding 2/123 94/18639 0.0212765957446809 3.22418266735859 0.127884778210149 0.387057444230452 GO:0043177 organic acid binding 3/123 189/18639 0.0158730158730159 2.40534262485482 0.129483335673729 0.387057444230452 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/123 21/18639 0.0476190476190476 7.21602787456446 0.129871665150894 0.387057444230452 GO:0036122 BMP binding 1/123 21/18639 0.0476190476190476 7.21602787456446 0.129871665150894 0.387057444230452 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/123 21/18639 0.0476190476190476 7.21602787456446 0.129871665150894 0.387057444230452 GO:0072542 protein phosphatase activator activity 1/123 21/18639 0.0476190476190476 7.21602787456446 0.129871665150894 0.387057444230452 GO:0004175 endopeptidase activity 5/123 405/18639 0.0123456790123457 1.87082204155375 0.13023344594107 0.387057444230452 GO:0004896 cytokine receptor activity 2/123 96/18639 0.0208333333333333 3.15701219512195 0.132318240246564 0.390480521478838 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.390480521478838 GO:0008236 serine-type peptidase activity 3/123 194/18639 0.0154639175257732 2.34334925823485 0.136941217899906 0.390480521478838 GO:0031625 ubiquitin protein ligase binding 4/123 302/18639 0.0132450331125828 2.00710709093846 0.139501360148138 0.390480521478838 GO:0004602 glutathione peroxidase activity 1/123 23/18639 0.0434782608695652 6.58854718981972 0.14133101708513 0.390480521478838 GO:0005212 structural constituent of eye lens 1/123 23/18639 0.0434782608695652 6.58854718981972 0.14133101708513 0.390480521478838 GO:0031681 G-protein beta-subunit binding 1/123 23/18639 0.0434782608695652 6.58854718981972 0.14133101708513 0.390480521478838 GO:0099186 structural constituent of postsynapse 1/123 23/18639 0.0434782608695652 6.58854718981972 0.14133101708513 0.390480521478838 GO:0017171 serine hydrolase activity 3/123 198/18639 0.0151515151515152 2.2960088691796 0.143011874587259 0.390480521478838 GO:0015149 hexose transmembrane transporter activity 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.390480521478838 GO:0030215 semaphorin receptor binding 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.390480521478838 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.390480521478838 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.390480521478838 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.390480521478838 GO:0050431 transforming growth factor beta binding 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.390480521478838 GO:0055056 D-glucose transmembrane transporter activity 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.390480521478838 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.390480521478838 GO:0019211 phosphatase activator activity 1/123 25/18639 0.04 6.06146341463415 0.152640663413107 0.402706470227482 GO:0005160 transforming growth factor beta receptor binding 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.402706470227482 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.402706470227482 GO:0015145 monosaccharide transmembrane transporter activity 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.402706470227482 GO:0019865 immunoglobulin binding 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.402706470227482 GO:0070006 metalloaminopeptidase activity 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.402706470227482 GO:0070412 R-SMAD binding 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.402706470227482 GO:0004364 glutathione transferase activity 1/123 27/18639 0.037037037037037 5.61246612466125 0.163802544074195 0.412559819312598 GO:0044389 ubiquitin-like protein ligase binding 4/123 322/18639 0.0124223602484472 1.88244205423421 0.164053198738421 0.412559819312598 GO:0005200 structural constituent of cytoskeleton 2/123 112/18639 0.0178571428571429 2.70601045296167 0.168908450541111 0.415980840842882 GO:0045499 chemorepellent activity 1/123 28/18639 0.0357142857142857 5.41202090592335 0.169328671684279 0.415980840842882 GO:0051019 mitogen-activated protein kinase binding 1/123 28/18639 0.0357142857142857 5.41202090592335 0.169328671684279 0.415980840842882 GO:0051119 sugar transmembrane transporter activity 1/123 28/18639 0.0357142857142857 5.41202090592335 0.169328671684279 0.415980840842882 GO:0003785 actin monomer binding 1/123 29/18639 0.0344827586206897 5.22539949537426 0.174818574074416 0.424036212480591 GO:0001221 transcription coregulator binding 2/123 115/18639 0.0173913043478261 2.63541887592789 0.175952986765281 0.424036212480591 GO:0009055 electron transfer activity 2/123 116/18639 0.0172413793103448 2.61269974768713 0.17831166682668 0.424036212480591 GO:0001968 fibronectin binding 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424036212480591 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424036212480591 GO:0033612 receptor serine/threonine kinase binding 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424036212480591 GO:0098918 structural constituent of synapse 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424036212480591 GO:0022853 active monoatomic ion transmembrane transporter activity 2/123 118/18639 0.0169491525423729 2.56841670111616 0.183043765725545 0.424036212480591 GO:0005184 neuropeptide hormone activity 1/123 31/18639 0.032258064516129 4.8882769472856 0.185690643804257 0.424036212480591 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/123 31/18639 0.032258064516129 4.8882769472856 0.185690643804257 0.424036212480591 GO:0005452 solute:inorganic anion antiporter activity 1/123 31/18639 0.032258064516129 4.8882769472856 0.185690643804257 0.424036212480591 GO:0047499 calcium-independent phospholipase A2 activity 1/123 31/18639 0.032258064516129 4.8882769472856 0.185690643804257 0.424036212480591 GO:0015108 chloride transmembrane transporter activity 2/123 121/18639 0.0165289256198347 2.50473694819593 0.19017629405311 0.424036212480591 GO:0015106 bicarbonate transmembrane transporter activity 1/123 32/18639 0.03125 4.73551829268293 0.191073277661312 0.424036212480591 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/123 32/18639 0.03125 4.73551829268293 0.191073277661312 0.424036212480591 GO:0042910 xenobiotic transmembrane transporter activity 1/123 32/18639 0.03125 4.73551829268293 0.191073277661312 0.424036212480591 GO:0047498 calcium-dependent phospholipase A2 activity 1/123 32/18639 0.03125 4.73551829268293 0.191073277661312 0.424036212480591 GO:0160041 neuropeptide activity 1/123 32/18639 0.03125 4.73551829268293 0.191073277661312 0.424036212480591 GO:0008528 G protein-coupled peptide receptor activity 2/123 122/18639 0.0163934426229508 2.48420631747301 0.192562327079421 0.424036212480591 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/123 122/18639 0.0163934426229508 2.48420631747301 0.192562327079421 0.424036212480591 GO:0030296 protein tyrosine kinase activator activity 1/123 33/18639 0.0303030303030303 4.5920177383592 0.196420619352485 0.43030290322065 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/123 349/18639 0.0114613180515759 1.73680900132784 0.199438424140814 0.433012534428476 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/123 34/18639 0.0294117647058824 4.45695839311334 0.201732898392561 0.433012534428476 GO:0019825 oxygen binding 1/123 34/18639 0.0294117647058824 4.45695839311334 0.201732898392561 0.433012534428476 GO:0090482 vitamin transmembrane transporter activity 1/123 34/18639 0.0294117647058824 4.45695839311334 0.201732898392561 0.433012534428476 GO:0001653 peptide receptor activity 2/123 128/18639 0.015625 2.36775914634146 0.206957139378894 0.435541562855404 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/123 128/18639 0.015625 2.36775914634146 0.206957139378894 0.435541562855404 GO:0004623 phospholipase A2 activity 1/123 35/18639 0.0285714285714286 4.32961672473868 0.20701034281598 0.435541562855404 GO:0016229 steroid dehydrogenase activity 1/123 35/18639 0.0285714285714286 4.32961672473868 0.20701034281598 0.435541562855404 GO:0004033 aldo-keto reductase (NADPH) activity 1/123 36/18639 0.0277777777777778 4.20934959349593 0.212253179186311 0.435785512822136 GO:0045505 dynein intermediate chain binding 1/123 36/18639 0.0277777777777778 4.20934959349593 0.212253179186311 0.435785512822136 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/123 36/18639 0.0277777777777778 4.20934959349593 0.212253179186311 0.435785512822136 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/123 36/18639 0.0277777777777778 4.20934959349593 0.212253179186311 0.435785512822136 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/123 36/18639 0.0277777777777778 4.20934959349593 0.212253179186311 0.435785512822136 GO:0005539 glycosaminoglycan binding 3/123 242/18639 0.012396694214876 1.87855271114695 0.214814133073012 0.438015136764947 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/123 484/18639 0.0103305785123967 1.56546059262246 0.215906415964164 0.438015136764947 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/123 132/18639 0.0151515151515152 2.2960088691796 0.216617616758084 0.438015136764947 GO:0030280 structural constituent of skin epidermis 1/123 37/18639 0.027027027027027 4.09558338826632 0.217461632605656 0.438015136764947 GO:0140297 DNA-binding transcription factor binding 5/123 488/18639 0.0102459016393443 1.55262894842063 0.220662134781693 0.441887455325542 GO:0051087 protein-folding chaperone binding 2/123 134/18639 0.0149253731343284 2.26174008008737 0.221463595257272 0.441887455325542 GO:0000146 microfilament motor activity 1/123 38/18639 0.0263157894736842 3.98780487804878 0.222635926724004 0.44215078905468 GO:0001216 DNA-binding transcription activator activity 5/123 491/18639 0.010183299389002 1.54314241716755 0.224250383091566 0.443285640994956 GO:0042277 peptide binding 3/123 249/18639 0.0120481927710843 1.82574199235968 0.226898552700803 0.444059268775776 GO:0000217 DNA secondary structure binding 1/123 39/18639 0.0256410256410256 3.88555347091932 0.227776283748516 0.444059268775776 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/123 39/18639 0.0256410256410256 3.88555347091932 0.227776283748516 0.444059268775776 GO:0004177 aminopeptidase activity 1/123 40/18639 0.025 3.78841463414634 0.232882924452759 0.445231743678222 GO:0015144 carbohydrate transmembrane transporter activity 1/123 40/18639 0.025 3.78841463414634 0.232882924452759 0.445231743678222 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/123 40/18639 0.025 3.78841463414634 0.232882924452759 0.445231743678222 GO:0140662 ATP-dependent protein folding chaperone 1/123 40/18639 0.025 3.78841463414634 0.232882924452759 0.445231743678222 GO:0030295 protein kinase activator activity 2/123 139/18639 0.0143884892086331 2.18038252324969 0.23361571491822 0.445231743678222 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/123 41/18639 0.024390243902439 3.69601427721594 0.23795606818588 0.449472573239996 GO:0017080 sodium channel regulator activity 1/123 41/18639 0.024390243902439 3.69601427721594 0.23795606818588 0.449472573239996 GO:0020037 heme binding 2/123 142/18639 0.0140845070422535 2.13431810374442 0.240927262266275 0.4529529450646 GO:0016859 cis-trans isomerase activity 1/123 42/18639 0.0238095238095238 3.60801393728223 0.242995932881715 0.4529529450646 GO:0042056 chemoattractant activity 1/123 42/18639 0.0238095238095238 3.60801393728223 0.242995932881715 0.4529529450646 GO:0019955 cytokine binding 2/123 144/18639 0.0138888888888889 2.10467479674797 0.245807982163385 0.456193853359993 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/123 43/18639 0.0232558139534884 3.5241066364152 0.24800273506785 0.456282088328295 GO:0008200 ion channel inhibitor activity 1/123 43/18639 0.0232558139534884 3.5241066364152 0.24800273506785 0.456282088328295 GO:0001046 core promoter sequence-specific DNA binding 1/123 44/18639 0.0227272727272727 3.4440133037694 0.252976689874617 0.457511034879627 GO:0001223 transcription coactivator binding 1/123 44/18639 0.0227272727272727 3.4440133037694 0.252976689874617 0.457511034879627 GO:0016248 channel inhibitor activity 1/123 44/18639 0.0227272727272727 3.4440133037694 0.252976689874617 0.457511034879627 GO:0019205 nucleobase-containing compound kinase activity 1/123 44/18639 0.0227272727272727 3.4440133037694 0.252976689874617 0.457511034879627 GO:0141110 transporter inhibitor activity 1/123 45/18639 0.0222222222222222 3.36747967479675 0.257918011044041 0.462703123373211 GO:0008509 monoatomic anion transmembrane transporter activity 2/123 149/18639 0.0134228187919463 2.03404812571616 0.258025035857532 0.462703123373211 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/123 46/18639 0.0217391304347826 3.29427359490986 0.262826910938715 0.467771841626513 GO:0046906 tetrapyrrole binding 2/123 152/18639 0.0131578947368421 1.99390243902439 0.265361129532332 0.467771841626513 GO:0001784 phosphotyrosine residue binding 1/123 47/18639 0.0212765957446809 3.22418266735859 0.267703600550641 0.467771841626513 GO:0005506 iron ion binding 2/123 154/18639 0.012987012987013 1.96800760215394 0.270252457324088 0.467771841626513 GO:0005004 GPI-linked ephrin receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0005008 hepatocyte growth factor receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0005009 insulin receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0005011 macrophage colony-stimulating factor receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0005020 stem cell factor receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0008288 boss receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0036332 placental growth factor receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0038062 protein tyrosine kinase collagen receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0060175 brain-derived neurotrophic factor receptor activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0060590 ATPase regulator activity 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.467771841626513 GO:0005006 epidermal growth factor receptor activity 1/123 50/18639 0.02 3.03073170731707 0.282142497234799 0.46840063017496 GO:0005007 fibroblast growth factor receptor activity 1/123 50/18639 0.02 3.03073170731707 0.282142497234799 0.46840063017496 GO:0005017 platelet-derived growth factor receptor activity 1/123 50/18639 0.02 3.03073170731707 0.282142497234799 0.46840063017496 GO:0005019 platelet-derived growth factor beta-receptor activity 1/123 50/18639 0.02 3.03073170731707 0.282142497234799 0.46840063017496 GO:0005010 insulin-like growth factor receptor activity 1/123 51/18639 0.0196078431372549 2.9713055954089 0.286892428529658 0.470769429054457 GO:0005021 vascular endothelial growth factor receptor activity 1/123 51/18639 0.0196078431372549 2.9713055954089 0.286892428529658 0.470769429054457 GO:0005030 neurotrophin receptor activity 1/123 51/18639 0.0196078431372549 2.9713055954089 0.286892428529658 0.470769429054457 GO:0005080 protein kinase C binding 1/123 52/18639 0.0192307692307692 2.91416510318949 0.291611184247909 0.474845798104832 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/123 52/18639 0.0192307692307692 2.91416510318949 0.291611184247909 0.474845798104832 GO:0005003 ephrin receptor activity 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.476519483153292 GO:0005005 transmembrane-ephrin receptor activity 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.476519483153292 GO:0038064 collagen receptor activity 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.476519483153292 GO:0015103 inorganic anion transmembrane transporter activity 2/123 165/18639 0.0121212121212121 1.83680709534368 0.297123913024994 0.476519483153292 GO:0015399 primary active transmembrane transporter activity 2/123 166/18639 0.0120481927710843 1.82574199235968 0.299561448404846 0.478622614932554 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/123 54/18639 0.0185185185185185 2.80623306233062 0.300955979447067 0.47904978001874 GO:0005201 extracellular matrix structural constituent 2/123 168/18639 0.0119047619047619 1.80400696864111 0.304432560843958 0.48277551626374 GO:0001664 G protein-coupled receptor binding 3/123 297/18639 0.0101010101010101 1.53067257945307 0.312332308929569 0.493461826375713 GO:0015459 potassium channel regulator activity 1/123 59/18639 0.0169491525423729 2.56841670111616 0.323786441939101 0.505916315529845 GO:0045309 protein phosphorylated amino acid binding 1/123 59/18639 0.0169491525423729 2.56841670111616 0.323786441939101 0.505916315529845 GO:0070063 RNA polymerase binding 1/123 59/18639 0.0169491525423729 2.56841670111616 0.323786441939101 0.505916315529845 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/123 60/18639 0.0166666666666667 2.52560975609756 0.328262990251345 0.509824385627693 GO:0005319 lipid transporter activity 2/123 178/18639 0.0112359550561798 1.70265826253768 0.328686780381148 0.509824385627693 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/123 61/18639 0.0163934426229508 2.48420631747301 0.332710143068993 0.512325401464935 GO:0019905 syntaxin binding 1/123 61/18639 0.0163934426229508 2.48420631747301 0.332710143068993 0.512325401464935 GO:0015179 L-amino acid transmembrane transporter activity 1/123 62/18639 0.0161290322580645 2.4441384736428 0.337128091847253 0.517254292545424 GO:0015078 proton transmembrane transporter activity 2/123 185/18639 0.0108108108108108 1.63823335530653 0.345534248690979 0.528244804653475 GO:0019843 rRNA binding 1/123 65/18639 0.0153846153846154 2.33133208255159 0.350208609994402 0.531566640170075 GO:0038024 cargo receptor activity 1/123 65/18639 0.0153846153846154 2.33133208255159 0.350208609994402 0.531566640170075 GO:0008235 metalloexopeptidase activity 1/123 66/18639 0.0151515151515152 2.2960088691796 0.354511632551239 0.536183074143333 GO:0016500 protein-hormone receptor activity 1/123 67/18639 0.0149253731343284 2.26174008008737 0.358786389951562 0.536916252568359 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/123 67/18639 0.0149253731343284 2.26174008008737 0.358786389951562 0.536916252568359 GO:0050840 extracellular matrix binding 1/123 67/18639 0.0149253731343284 2.26174008008737 0.358786389951562 0.536916252568359 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/123 68/18639 0.0147058823529412 2.22847919655667 0.363033066348071 0.539472213978776 GO:1990841 promoter-specific chromatin binding 1/123 68/18639 0.0147058823529412 2.22847919655667 0.363033066348071 0.539472213978776 GO:0008080 N-acetyltransferase activity 1/123 69/18639 0.0144927536231884 2.19618239660657 0.367251844703527 0.543839839717767 GO:0097110 scaffold protein binding 1/123 70/18639 0.0142857142857143 2.16480836236934 0.371442906798383 0.548136233990669 GO:0003924 GTPase activity 3/123 331/18639 0.00906344410876133 1.37344337189595 0.373658525295053 0.549497831316254 GO:0005518 collagen binding 1/123 72/18639 0.0138888888888889 2.10467479674797 0.379742603461946 0.556519332659749 GO:0043539 protein serine/threonine kinase activator activity 1/123 73/18639 0.0136986301369863 2.07584363514868 0.383851595747947 0.560608000662809 GO:0048029 monosaccharide binding 1/123 74/18639 0.0135135135135135 2.04779169413316 0.387933587222848 0.564629364964761 GO:0051540 metal cluster binding 1/123 77/18639 0.012987012987013 1.96800760215394 0.400019310916264 0.573703284318899 GO:0019199 transmembrane receptor protein kinase activity 1/123 78/18639 0.0128205128205128 1.94277673545966 0.40399504762337 0.573703284318899 GO:0030695 GTPase regulator activity 4/123 489/18639 0.0081799591002045 1.23956307047733 0.40428482592373 0.573703284318899 GO:0060589 nucleoside-triphosphatase regulator activity 4/123 490/18639 0.00816326530612245 1.23703334992534 0.405776451726374 0.573703284318899 GO:0016835 carbon-oxygen lyase activity 1/123 79/18639 0.0126582278481013 1.91818462488422 0.40794465212433 0.573703284318899 GO:0046332 SMAD binding 1/123 79/18639 0.0126582278481013 1.91818462488422 0.40794465212433 0.573703284318899 GO:0000049 tRNA binding 1/123 80/18639 0.0125 1.89420731707317 0.41186829478536 0.573703284318899 GO:0015101 organic cation transmembrane transporter activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.573703284318899 GO:0033192 calmodulin-dependent protein phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.573703284318899 GO:0140791 histone H2AXS140 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.573703284318899 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.573703284318899 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.573703284318899 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.573703284318899 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.573703284318899 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.573703284318899 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.573703284318899 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/123 82/18639 0.0121951219512195 1.84800713860797 0.419638370551723 0.575019757305734 GO:0033549 MAP kinase phosphatase activity 1/123 82/18639 0.0121951219512195 1.84800713860797 0.419638370551723 0.575019757305734 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/123 83/18639 0.0120481927710843 1.82574199235968 0.42348513890987 0.575019757305734 GO:0005254 chloride channel activity 1/123 83/18639 0.0120481927710843 1.82574199235968 0.42348513890987 0.575019757305734 GO:0008135 translation factor activity, RNA binding 1/123 83/18639 0.0120481927710843 1.82574199235968 0.42348513890987 0.575019757305734 GO:0017018 myosin phosphatase activity 1/123 84/18639 0.0119047619047619 1.80400696864111 0.427306615947706 0.576524799294524 GO:0180051 translation factor activity 1/123 84/18639 0.0119047619047619 1.80400696864111 0.427306615947706 0.576524799294524 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/123 86/18639 0.0116279069767442 1.7620533182076 0.434874354710062 0.584878483391697 GO:0046982 protein heterodimerization activity 3/123 369/18639 0.00813008130081301 1.23200475907198 0.440910839195682 0.589935546185004 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/123 88/18639 0.0113636363636364 1.7220066518847 0.442342893508098 0.589935546185004 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/123 89/18639 0.0112359550561798 1.70265826253768 0.446040366641541 0.589935546185004 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/123 89/18639 0.0112359550561798 1.70265826253768 0.446040366641541 0.589935546185004 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/123 229/18639 0.00873362445414847 1.32346362764938 0.447519209253348 0.589935546185004 GO:0140793 histone H2AXY142 phosphatase activity 1/123 90/18639 0.0111111111111111 1.68373983739837 0.449713522161923 0.589935546185004 GO:0000287 magnesium ion binding 2/123 230/18639 0.00869565217391304 1.31770943796394 0.449739098738686 0.589935546185004 GO:0005085 guanyl-nucleotide exchange factor activity 2/123 230/18639 0.00869565217391304 1.31770943796394 0.449739098738686 0.589935546185004 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/123 91/18639 0.010989010989011 1.66523720182257 0.453362518699423 0.592858678299245 GO:0005525 GTP binding 3/123 378/18639 0.00793650793650794 1.20267131242741 0.456468346337176 0.595089101819939 GO:0051219 phosphoprotein binding 1/123 93/18639 0.010752688172043 1.6294256490952 0.460588664221625 0.598624410685598 GO:0015631 tubulin binding 3/123 385/18639 0.00779220779220779 1.18080456129237 0.468445531779134 0.606979728677232 GO:0016407 acetyltransferase activity 1/123 96/18639 0.0104166666666667 1.57850609756098 0.47125059722723 0.608758370278337 GO:0004725 protein tyrosine phosphatase activity 1/123 98/18639 0.0102040816326531 1.54629168740667 0.478242154005972 0.61405714638229 GO:0042626 ATPase-coupled transmembrane transporter activity 1/123 98/18639 0.0102040816326531 1.54629168740667 0.478242154005972 0.61405714638229 GO:0043130 ubiquitin binding 1/123 100/18639 0.01 1.51536585365854 0.485142004449921 0.621040216539808 GO:0008238 exopeptidase activity 1/123 102/18639 0.00980392156862745 1.48565279770445 0.491951341714605 0.62281667317714 GO:0015171 amino acid transmembrane transporter activity 1/123 102/18639 0.00980392156862745 1.48565279770445 0.491951341714605 0.62281667317714 GO:0019001 guanyl nucleotide binding 3/123 400/18639 0.0075 1.1365243902439 0.493712630713732 0.62281667317714 GO:0032561 guanyl ribonucleotide binding 3/123 400/18639 0.0075 1.1365243902439 0.493712630713732 0.62281667317714 GO:0004722 protein serine/threonine phosphatase activity 1/123 103/18639 0.00970873786407767 1.4712289841345 0.49532243655029 0.62281667317714 GO:0005253 monoatomic anion channel activity 1/123 103/18639 0.00970873786407767 1.4712289841345 0.49532243655029 0.62281667317714 GO:0000149 SNARE binding 1/123 106/18639 0.00943396226415094 1.42959042797975 0.505303172540122 0.63349217796328 GO:0019888 protein phosphatase regulator activity 1/123 107/18639 0.00934579439252336 1.41622976977433 0.508586381398783 0.635732976748479 GO:0004620 phospholipase activity 1/123 109/18639 0.00917431192660551 1.39024390243902 0.515088098112344 0.641971969788112 GO:0003730 mRNA 3'-UTR binding 2/123 262/18639 0.00763358778625954 1.15676782722026 0.518008379903652 0.643723863915357 GO:1902936 phosphatidylinositol bisphosphate binding 1/123 111/18639 0.00900900900900901 1.36519446275544 0.521504483130596 0.646179024287182 GO:0043022 ribosome binding 1/123 112/18639 0.00892857142857143 1.35300522648084 0.524681023964735 0.648225102282013 GO:0017124 SH3 domain binding 1/123 115/18639 0.00869565217391304 1.31770943796394 0.534085687235527 0.654139530475789 GO:0035401 histone H3Y41 kinase activity 1/123 115/18639 0.00869565217391304 1.31770943796394 0.534085687235527 0.654139530475789 GO:0140801 histone H2AXY142 kinase activity 1/123 115/18639 0.00869565217391304 1.31770943796394 0.534085687235527 0.654139530475789 GO:0005096 GTPase activator activity 2/123 271/18639 0.00738007380073801 1.11835118351183 0.536186093244925 0.654824970198543 GO:0016791 phosphatase activity 2/123 273/18639 0.00732600732600733 1.11015813454838 0.540162018395866 0.656021117771669 GO:0019208 phosphatase regulator activity 1/123 117/18639 0.00854700854700855 1.29518449030644 0.540252685223728 0.656021117771669 GO:1901681 sulfur compound binding 2/123 275/18639 0.00727272727272727 1.10208425720621 0.544114631368635 0.658828257355184 GO:0008017 microtubule binding 2/123 276/18639 0.0072463768115942 1.09809119830329 0.546082170826608 0.65933216648099 GO:0032182 ubiquitin-like protein binding 1/123 120/18639 0.00833333333333333 1.26280487804878 0.549351686936793 0.661400756227017 GO:0030246 carbohydrate binding 2/123 280/18639 0.00714285714285714 1.08240418118467 0.553893668680181 0.664985336692307 GO:0003779 actin binding 3/123 443/18639 0.00677200902934537 1.02620712437373 0.562673245341315 0.673622899352279 GO:0016298 lipase activity 1/123 130/18639 0.00769230769230769 1.1656660412758 0.578410890758496 0.686660973665813 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/123 130/18639 0.00769230769230769 1.1656660412758 0.578410890758496 0.686660973665813 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/123 130/18639 0.00769230769230769 1.1656660412758 0.578410890758496 0.686660973665813 GO:0031072 heat shock protein binding 1/123 131/18639 0.00763358778625954 1.15676782722026 0.581212525662419 0.688064967706207 GO:0022804 active transmembrane transporter activity 3/123 457/18639 0.00656455142231947 0.994769706996851 0.583886784592684 0.689310787366363 GO:0015297 antiporter activity 1/123 135/18639 0.00740740740740741 1.12249322493225 0.5922355921926 0.697230267816773 GO:0140789 histone phosphatase activity 1/123 136/18639 0.00735294117647059 1.11423959827834 0.594946088418298 0.698486429772863 GO:0004713 protein tyrosine kinase activity 1/123 140/18639 0.00714285714285714 1.08240418118467 0.605610521060225 0.709048130717894 GO:0000510 H3-H4 histone complex chaperone activity 1/123 151/18639 0.00662251655629139 1.00355354546923 0.633523017802913 0.731301560104606 GO:0140584 chromatin extrusion motor activity 1/123 151/18639 0.00662251655629139 1.00355354546923 0.633523017802913 0.731301560104606 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/123 151/18639 0.00662251655629139 1.00355354546923 0.633523017802913 0.731301560104606 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/123 151/18639 0.00662251655629139 1.00355354546923 0.633523017802913 0.731301560104606 GO:0015616 DNA translocase activity 1/123 152/18639 0.00657894736842105 0.996951219512195 0.63596117600338 0.731301560104606 GO:0140674 ATP-dependent histone chaperone activity 1/123 152/18639 0.00657894736842105 0.996951219512195 0.63596117600338 0.731301560104606 GO:0003774 cytoskeletal motor activity 1/123 153/18639 0.0065359477124183 0.990435198469632 0.638383244232492 0.731301560104606 GO:0061775 cohesin loader activity 1/123 153/18639 0.0065359477124183 0.990435198469632 0.638383244232492 0.731301560104606 GO:0140658 ATP-dependent chromatin remodeler activity 1/123 158/18639 0.00632911392405063 0.959092312442112 0.650255898059104 0.742899883535266 GO:0003689 DNA clamp loader activity 1/123 160/18639 0.00625 0.947103658536585 0.654895963657532 0.746195132853756 GO:0005178 integrin binding 1/123 161/18639 0.0062111801242236 0.941221027117103 0.657193046642007 0.746810280275008 GO:0140713 histone chaperone activity 1/123 164/18639 0.00609756097560976 0.924003569303986 0.663993694028948 0.752526186566141 GO:0141003 histone H2AX kinase activity 2/123 354/18639 0.00564971751412429 0.856138900372055 0.68126263763098 0.768248390618977 GO:0008201 heparin binding 1/123 172/18639 0.00581395348837209 0.8810266591038 0.681481513560834 0.768248390618977 GO:0140996 histone H3 kinase activity 2/123 357/18639 0.00560224089635854 0.848944455831113 0.685747503797413 0.771012405063229 GO:0004721 phosphoprotein phosphatase activity 1/123 175/18639 0.00571428571428571 0.865923344947735 0.687804062211465 0.771284238627632 GO:0035173 histone kinase activity 2/123 360/18639 0.00555555555555556 0.841869918699187 0.690181061542461 0.771859986395755 GO:0043021 ribonucleoprotein complex binding 1/123 177/18639 0.00564971751412429 0.856138900372055 0.691949776039489 0.771859986395755 GO:0042578 phosphoric ester hydrolase activity 2/123 363/18639 0.00550964187327824 0.834912316065309 0.6945635756942 0.772747433691191 GO:1901981 phosphatidylinositol phosphate binding 1/123 185/18639 0.00540540540540541 0.819116677653263 0.707993619563439 0.785632606565174 GO:0140597 protein carrier chaperone 1/123 188/18639 0.00531914893617021 0.806045666839647 0.713793962676222 0.790006338899464 GO:0019902 phosphatase binding 1/123 190/18639 0.00526315789473684 0.797560975609756 0.717597220183744 0.79215277552751 GO:0016829 lyase activity 1/123 200/18639 0.005 0.757682926829268 0.735874477788033 0.810224489792524 GO:0005516 calmodulin binding 1/123 207/18639 0.00483091787439614 0.732060798868858 0.747965531070886 0.821409174948648 GO:0008094 ATP-dependent activity, acting on DNA 1/123 210/18639 0.00476190476190476 0.721602787456446 0.752977817756741 0.824782403470657 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/123 243/18639 0.00411522633744856 0.623607347184583 0.801994180478567 0.835359270318775 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0004711 ribosomal protein S6 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0035175 histone H3S10 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0035979 histone H2AXS139 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0044022 histone H3S28 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0044023 histone H4S1 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0044024 histone H2AS1 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0044025 histone H2BS14 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0072354 histone H3T3 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0072371 histone H2AS121 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0140823 histone H2BS36 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0140855 histone H3S57 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0140995 histone H2A kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0140997 histone H4 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0140998 histone H2B kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:1990244 histone H2AT120 kinase activity 1/123 245/18639 0.00408163265306122 0.618516674962668 0.804633227301491 0.835359270318775 GO:0004677 DNA-dependent protein kinase activity 1/123 246/18639 0.0040650406504065 0.616002379535991 0.805939637709337 0.835359270318775 GO:0140857 histone H3T45 kinase activity 1/123 246/18639 0.0040650406504065 0.616002379535991 0.805939637709337 0.835359270318775 GO:0035402 histone H3T11 kinase activity 1/123 247/18639 0.00404858299595142 0.613508442776736 0.807237382751568 0.835359270318775 GO:0035403 histone H3T6 kinase activity 1/123 247/18639 0.00404858299595142 0.613508442776736 0.807237382751568 0.835359270318775 GO:0004679 AMP-activated protein kinase activity 1/123 248/18639 0.00403225806451613 0.6110346184107 0.808526519437168 0.835359270318775 GO:0140104 molecular carrier activity 1/123 249/18639 0.00401606425702811 0.608580664119894 0.809807104403142 0.835359270318775 GO:0003713 transcription coactivator activity 1/123 256/18639 0.00390625 0.591939786585366 0.81853643151304 0.842319572380247 GO:0005543 phospholipid binding 2/123 497/18639 0.00402414486921529 0.609805172498405 0.843618576222064 0.866033562546805 GO:0031267 small GTPase binding 1/123 283/18639 0.00353356890459364 0.53546496595708 0.848639707652033 0.868035879929783 GO:0035091 phosphatidylinositol binding 1/123 284/18639 0.00352112676056338 0.533579525936104 0.849653943648917 0.868035879929783 GO:0015291 secondary active transmembrane transporter activity 1/123 287/18639 0.00348432055749129 0.528002039602278 0.852656381244016 0.869014297430951 GO:0051020 GTPase binding 1/123 315/18639 0.00317460317460317 0.481068524970964 0.877961922928542 0.892664634556532 GO:0140097 catalytic activity, acting on DNA 1/123 336/18639 0.00297619047619048 0.451001742160279 0.894065848258963 0.906868700501335 GO:0106310 protein serine kinase activity 1/123 361/18639 0.00277008310249307 0.419768934531451 0.910509328130079 0.921348724893532 GO:0016887 ATP hydrolysis activity 1/123 417/18639 0.00239808153477218 0.363397087208282 0.93872069184336 0.947639653286052 GO:0004674 protein serine/threonine kinase activity 1/123 433/18639 0.0023094688221709 0.349969019320678 0.945016673706199 0.951734801718329 GO:0005216 monoatomic ion channel activity 1/123 448/18639 0.00223214285714286 0.338251306620209 0.950334693268107 0.954828001510509 GO:0003712 transcription coregulator activity 1/123 495/18639 0.00202020202020202 0.306134515890613 0.963909574044712 0.964154234670401 GO:0016755 aminoacyltransferase activity 1/123 496/18639 0.00201612903225806 0.30551730920535 0.964154234670401 0.964154234670401