ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0030165 PDZ domain binding 6/123 83/18639 0.072289156626506 10.9544519541581 1.82111821350096e-05 0.0079947089572692 GO:0017124 SH3 domain binding 5/123 115/18639 0.0434782608695652 6.58854718981972 0.000992499470821523 0.215046806068866 GO:0034452 dynactin binding 2/123 12/18639 0.166666666666667 25.2560975609756 0.00273018103004573 0.215046806068866 GO:0046982 protein heterodimerization activity 8/123 369/18639 0.021680216802168 3.28534602419195 0.00312810456730084 0.215046806068866 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/123 45/18639 0.0666666666666667 10.1024390243902 0.0032512574486975 0.215046806068866 GO:0001664 G protein-coupled receptor binding 7/123 297/18639 0.0235690235690236 3.57156935205716 0.00358332319098165 0.215046806068866 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 9/123 484/18639 0.0185950413223141 2.81782906672042 0.00481823526461196 0.215046806068866 GO:0001216 DNA-binding transcription activator activity 9/123 491/18639 0.0183299389002037 2.77765635090159 0.00528299488217901 0.215046806068866 GO:0008013 beta-catenin binding 4/123 106/18639 0.0377358490566038 5.71836171191901 0.00534571460418051 0.215046806068866 GO:0017075 syntaxin-1 binding 2/123 18/18639 0.111111111111111 16.8373983739837 0.00616747826262418 0.215046806068866 GO:0031690 adrenergic receptor binding 2/123 18/18639 0.111111111111111 16.8373983739837 0.00616747826262418 0.215046806068866 GO:0098641 cadherin binding involved in cell-cell adhesion 2/123 18/18639 0.111111111111111 16.8373983739837 0.00616747826262418 0.215046806068866 GO:0070888 E-box binding 3/123 59/18639 0.0508474576271186 7.70525010334849 0.00696713430636316 0.215046806068866 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/123 60/18639 0.05 7.57682926829268 0.00729898725049191 0.215046806068866 GO:0008093 cytoskeletal anchor activity 2/123 22/18639 0.0909090909090909 13.7760532150776 0.00915292581717229 0.215046806068866 GO:0050321 tau-protein kinase activity 2/123 22/18639 0.0909090909090909 13.7760532150776 0.00915292581717229 0.215046806068866 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/123 23/18639 0.0869565217391304 13.1770943796394 0.00998168472511283 0.215046806068866 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/123 24/18639 0.0833333333333333 12.6280487804878 0.010842482885186 0.215046806068866 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/123 24/18639 0.0833333333333333 12.6280487804878 0.010842482885186 0.215046806068866 GO:0030552 cAMP binding 2/123 24/18639 0.0833333333333333 12.6280487804878 0.010842482885186 0.215046806068866 GO:0097110 scaffold protein binding 3/123 70/18639 0.0428571428571429 6.49442508710801 0.0111337908064148 0.215046806068866 GO:0035091 phosphatidylinositol binding 6/123 284/18639 0.0211267605633803 3.20147715561663 0.0114443864795534 0.215046806068866 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/123 26/18639 0.0769230769230769 11.656660412758 0.0126583941531578 0.215046806068866 GO:0008143 poly(A) binding 2/123 26/18639 0.0769230769230769 11.656660412758 0.0126583941531578 0.215046806068866 GO:0050750 low-density lipoprotein particle receptor binding 2/123 26/18639 0.0769230769230769 11.656660412758 0.0126583941531578 0.215046806068866 GO:0008266 poly(U) RNA binding 2/123 27/18639 0.0740740740740741 11.2249322493225 0.0136126170255428 0.215046806068866 GO:0004713 protein tyrosine kinase activity 4/123 140/18639 0.0285714285714286 4.32961672473868 0.0139132846264369 0.215046806068866 GO:0046875 ephrin receptor binding 2/123 28/18639 0.0714285714285714 10.8240418118467 0.0145970986019417 0.215046806068866 GO:0141052 histone H3 demethylase activity 2/123 28/18639 0.0714285714285714 10.8240418118467 0.0145970986019417 0.215046806068866 GO:0046332 SMAD binding 3/123 79/18639 0.0379746835443038 5.75455387465267 0.0154125694141266 0.215046806068866 GO:0030695 GTPase regulator activity 8/123 489/18639 0.016359918200409 2.47912614095466 0.0158402400942674 0.215046806068866 GO:0060589 nucleoside-triphosphatase regulator activity 8/123 490/18639 0.0163265306122449 2.47406669985067 0.0160166001230719 0.215046806068866 GO:0008187 poly-pyrimidine tract binding 2/123 30/18639 0.0666666666666667 10.1024390243902 0.016655105709206 0.215046806068866 GO:0032452 histone demethylase activity 2/123 30/18639 0.0666666666666667 10.1024390243902 0.016655105709206 0.215046806068866 GO:0070325 lipoprotein particle receptor binding 2/123 31/18639 0.0645161290322581 9.7765538945712 0.0177277759488874 0.216180378932265 GO:0140457 protein demethylase activity 2/123 31/18639 0.0645161290322581 9.7765538945712 0.0177277759488874 0.216180378932265 GO:0005085 guanyl-nucleotide exchange factor activity 5/123 230/18639 0.0217391304347826 3.29427359490986 0.0182954943746797 0.21707356839147 GO:0070717 poly-purine tract binding 2/123 32/18639 0.0625 9.47103658536585 0.0188289942355574 0.217524433405518 GO:0140311 protein sequestering activity 2/123 33/18639 0.0606060606060606 9.1840354767184 0.0199583435437716 0.22465930296707 GO:0003727 single-stranded RNA binding 3/123 89/18639 0.0337078651685393 5.10797478761304 0.0211122443379615 0.231706881609127 GO:0051213 dioxygenase activity 3/123 93/18639 0.032258064516129 4.8882769472856 0.0236736482014594 0.252668554033828 GO:0030551 cyclic nucleotide binding 2/123 37/18639 0.0540540540540541 8.19116677653263 0.0247488560898738 0.252668554033828 GO:0043394 proteoglycan binding 2/123 37/18639 0.0540540540540541 8.19116677653263 0.0247488560898738 0.252668554033828 GO:0032451 demethylase activity 2/123 40/18639 0.05 7.57682926829268 0.0286172962830122 0.285522569732781 GO:0035198 miRNA binding 2/123 42/18639 0.0476190476190476 7.21602787456446 0.031321615656651 0.302805265769913 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 5/123 268/18639 0.0186567164179104 2.82717510010921 0.032551181566221 0.302805265769913 GO:0048156 tau protein binding 2/123 43/18639 0.0465116279069767 7.0482132728304 0.0327102410640531 0.302805265769913 GO:0000149 SNARE binding 3/123 106/18639 0.0283018867924528 4.28877128393925 0.0331085484213117 0.302805265769913 GO:0005096 GTPase activator activity 5/123 271/18639 0.018450184501845 2.79587795877959 0.0339055345095231 0.303765911217973 GO:0030276 clathrin binding 2/123 46/18639 0.0434782608695652 6.58854718981972 0.0370175157836754 0.320218868411263 GO:0001217 DNA-binding transcription repressor activity 5/123 278/18639 0.0179856115107914 2.72547815406212 0.0372008252596228 0.320218868411263 GO:0005200 structural constituent of cytoskeleton 3/123 112/18639 0.0267857142857143 4.05901567944251 0.0380306881456228 0.321066771075547 GO:0035254 glutamate receptor binding 2/123 49/18639 0.0408163265306122 6.18516674962668 0.0415292534854117 0.343987590190485 GO:0005543 phospholipid binding 7/123 497/18639 0.0140845070422535 2.13431810374442 0.0466795238932166 0.379487240539298 GO:0051018 protein kinase A binding 2/123 53/18639 0.0377358490566038 5.71836171191901 0.047846463445715 0.381901771866707 GO:0140463 chromatin-protein adaptor activity 2/123 54/18639 0.037037037037037 5.61246612466125 0.0494773256793928 0.386987133349479 GO:0098632 cell-cell adhesion mediator activity 2/123 55/18639 0.0363636363636364 5.51042128603104 0.0511281406247604 0.386987133349479 GO:0140313 molecular sequestering activity 2/123 55/18639 0.0363636363636364 5.51042128603104 0.0511281406247604 0.386987133349479 GO:0016504 peptidase activator activity 2/123 57/18639 0.0350877192982456 5.31707317073171 0.0544883139563805 0.405429997065271 GO:0061980 regulatory RNA binding 2/123 58/18639 0.0344827586206897 5.22539949537426 0.0561970235077903 0.411174888665332 GO:0044325 transmembrane transporter binding 3/123 136/18639 0.0220588235294118 3.34271879483501 0.0611762149900632 0.41905808752748 GO:0019905 syntaxin binding 2/123 61/18639 0.0327868852459016 4.96841263494602 0.0614338211924572 0.41905808752748 GO:0061134 peptidase regulator activity 4/123 226/18639 0.0176991150442478 2.68206345780272 0.0627978691033975 0.41905808752748 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/123 10/18639 0.1 15.1536585365854 0.0640801244268342 0.41905808752748 GO:0030957 Tat protein binding 1/123 10/18639 0.1 15.1536585365854 0.0640801244268342 0.41905808752748 GO:0035256 G protein-coupled glutamate receptor binding 1/123 10/18639 0.1 15.1536585365854 0.0640801244268342 0.41905808752748 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.41905808752748 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.41905808752748 GO:0050786 RAGE receptor binding 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.41905808752748 GO:0050998 nitric-oxide synthase binding 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.41905808752748 GO:0097493 structural molecule activity conferring elasticity 1/123 11/18639 0.0909090909090909 13.7760532150776 0.0702596372667879 0.41905808752748 GO:0017166 vinculin binding 1/123 12/18639 0.0833333333333333 12.6280487804878 0.0763986787428554 0.41905808752748 GO:0035497 cAMP response element binding 1/123 12/18639 0.0833333333333333 12.6280487804878 0.0763986787428554 0.41905808752748 GO:0045295 gamma-catenin binding 1/123 12/18639 0.0833333333333333 12.6280487804878 0.0763986787428554 0.41905808752748 GO:0005518 collagen binding 2/123 72/18639 0.0277777777777778 4.20934959349593 0.08193834736322 0.41905808752748 GO:0004535 poly(A)-specific ribonuclease activity 1/123 13/18639 0.0769230769230769 11.656660412758 0.0824975117548608 0.41905808752748 GO:0046974 histone H3K9 methyltransferase activity 1/123 13/18639 0.0769230769230769 11.656660412758 0.0824975117548608 0.41905808752748 GO:0070700 BMP receptor binding 1/123 13/18639 0.0769230769230769 11.656660412758 0.0824975117548608 0.41905808752748 GO:0071837 HMG box domain binding 1/123 13/18639 0.0769230769230769 11.656660412758 0.0824975117548608 0.41905808752748 GO:0141003 histone H2AX kinase activity 5/123 354/18639 0.0141242937853107 2.14034725093014 0.0854389190653861 0.41905808752748 GO:0140996 histone H3 kinase activity 5/123 357/18639 0.0140056022408964 2.12236113957778 0.0878088504300814 0.41905808752748 GO:0003725 double-stranded RNA binding 2/123 75/18639 0.0266666666666667 4.0409756097561 0.087851255464289 0.41905808752748 GO:0005545 1-phosphatidylinositol binding 1/123 14/18639 0.0714285714285714 10.8240418118467 0.088556397508869 0.41905808752748 GO:0019992 diacylglycerol binding 1/123 14/18639 0.0714285714285714 10.8240418118467 0.088556397508869 0.41905808752748 GO:0032454 histone H3K9 demethylase activity 1/123 14/18639 0.0714285714285714 10.8240418118467 0.088556397508869 0.41905808752748 GO:0034236 protein kinase A catalytic subunit binding 1/123 14/18639 0.0714285714285714 10.8240418118467 0.088556397508869 0.41905808752748 GO:0042813 Wnt receptor activity 1/123 14/18639 0.0714285714285714 10.8240418118467 0.088556397508869 0.41905808752748 GO:0098631 cell adhesion mediator activity 2/123 76/18639 0.0263157894736842 3.98780487804878 0.0898500043764461 0.41905808752748 GO:0035173 histone kinase activity 5/123 360/18639 0.0138888888888889 2.10467479674797 0.0902131007824406 0.41905808752748 GO:0005178 integrin binding 3/123 161/18639 0.0186335403726708 2.82366308135131 0.0907322825632191 0.41905808752748 GO:0004089 carbonate dehydratase activity 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.41905808752748 GO:0033130 acetylcholine receptor binding 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.41905808752748 GO:0051371 muscle alpha-actinin binding 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.41905808752748 GO:0120283 protein serine/threonine kinase binding 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.41905808752748 GO:0140776 protein-containing complex destabilizing activity 1/123 15/18639 0.0666666666666667 10.1024390243902 0.0945755955280049 0.41905808752748 GO:0005201 extracellular matrix structural constituent 3/123 168/18639 0.0178571428571429 2.70601045296167 0.0999037343004508 0.41905808752748 GO:0008142 oxysterol binding 1/123 16/18639 0.0625 9.47103658536585 0.100555363663209 0.41905808752748 GO:0070411 I-SMAD binding 1/123 16/18639 0.0625 9.47103658536585 0.100555363663209 0.41905808752748 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/123 16/18639 0.0625 9.47103658536585 0.100555363663209 0.41905808752748 GO:0140297 DNA-binding transcription factor binding 6/123 488/18639 0.0122950819672131 1.86315473810476 0.104320046519764 0.41905808752748 GO:0008201 heparin binding 3/123 172/18639 0.0174418604651163 2.6430799773114 0.105306244598512 0.41905808752748 GO:0004860 protein kinase inhibitor activity 2/123 84/18639 0.0238095238095238 3.60801393728223 0.106302544769477 0.41905808752748 GO:0051117 ATPase binding 2/123 84/18639 0.0238095238095238 3.60801393728223 0.106302544769477 0.41905808752748 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.41905808752748 GO:0019198 transmembrane receptor protein phosphatase activity 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.41905808752748 GO:0030548 acetylcholine receptor regulator activity 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.41905808752748 GO:0046965 nuclear retinoid X receptor binding 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.41905808752748 GO:1990226 histone methyltransferase binding 1/123 17/18639 0.0588235294117647 8.91391678622669 0.106495958103924 0.41905808752748 GO:0004970 glutamate-gated receptor activity 1/123 18/18639 0.0555555555555556 8.41869918699187 0.112397633388707 0.41905808752748 GO:0015280 ligand-gated sodium channel activity 1/123 18/18639 0.0555555555555556 8.41869918699187 0.112397633388707 0.41905808752748 GO:0017128 phospholipid scramblase activity 1/123 18/18639 0.0555555555555556 8.41869918699187 0.112397633388707 0.41905808752748 GO:0034185 apolipoprotein binding 1/123 18/18639 0.0555555555555556 8.41869918699187 0.112397633388707 0.41905808752748 GO:0099602 neurotransmitter receptor regulator activity 1/123 18/18639 0.0555555555555556 8.41869918699187 0.112397633388707 0.41905808752748 GO:0008081 phosphoric diester hydrolase activity 2/123 87/18639 0.0229885057471264 3.48359966358284 0.112667753304523 0.41905808752748 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/123 181/18639 0.0165745856353591 2.51165611103625 0.117869608350201 0.41905808752748 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/123 19/18639 0.0526315789473684 7.97560975609756 0.118260642415783 0.41905808752748 GO:0043395 heparan sulfate proteoglycan binding 1/123 19/18639 0.0526315789473684 7.97560975609756 0.118260642415783 0.41905808752748 GO:0019210 kinase inhibitor activity 2/123 90/18639 0.0222222222222222 3.36747967479675 0.119129525327522 0.41905808752748 GO:1901981 phosphatidylinositol phosphate binding 3/123 185/18639 0.0162162162162162 2.45735003295979 0.123625996976993 0.41905808752748 GO:0016004 phospholipase activator activity 1/123 20/18639 0.05 7.57682926829268 0.12408523645353 0.41905808752748 GO:0008373 sialyltransferase activity 1/123 21/18639 0.0476190476190476 7.21602787456446 0.129871665150894 0.41905808752748 GO:0061891 calcium ion sensor activity 1/123 21/18639 0.0476190476190476 7.21602787456446 0.129871665150894 0.41905808752748 GO:0004867 serine-type endopeptidase inhibitor activity 2/123 95/18639 0.0210526315789474 3.19024390243902 0.130097036196263 0.41905808752748 GO:0019902 phosphatase binding 3/123 190/18639 0.0157894736842105 2.39268292682927 0.13096300172713 0.41905808752748 GO:0031683 G-protein beta/gamma-subunit complex binding 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0032931 histone H3K56 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0043992 histone H3K9 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0043993 histone H3K18 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0043994 histone H3K23 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0043999 histone H2AK5 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0044012 histone H2AK9 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0044014 histone H2BK5 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0044015 histone H2BK12 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0044016 histone H3K4 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0044017 histone H3K27 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0044018 histone H3K36 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0046972 histone H4K16 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0140517 protein-RNA adaptor activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0140784 metal ion sensor activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0140908 histone H3K122 acetyltransferase activity 1/123 22/18639 0.0454545454545455 6.8880266075388 0.135620176547738 0.41905808752748 GO:0004857 enzyme inhibitor activity 5/123 416/18639 0.0120192307692308 1.82135318949343 0.141080187453022 0.41905808752748 GO:0003887 DNA-directed DNA polymerase activity 1/123 23/18639 0.0434782608695652 6.58854718981972 0.14133101708513 0.41905808752748 GO:0005158 insulin receptor binding 1/123 23/18639 0.0434782608695652 6.58854718981972 0.14133101708513 0.41905808752748 GO:0005212 structural constituent of eye lens 1/123 23/18639 0.0434782608695652 6.58854718981972 0.14133101708513 0.41905808752748 GO:0043274 phospholipase binding 1/123 23/18639 0.0434782608695652 6.58854718981972 0.14133101708513 0.41905808752748 GO:0044013 histone H2B acetyltransferase activity 1/123 23/18639 0.0434782608695652 6.58854718981972 0.14133101708513 0.41905808752748 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.41905808752748 GO:0035035 histone acetyltransferase binding 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.41905808752748 GO:0043998 histone H2A acetyltransferase activity 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.41905808752748 GO:0050699 WW domain binding 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.41905808752748 GO:0060229 lipase activator activity 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.41905808752748 GO:0070300 phosphatidic acid binding 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.41905808752748 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.41905808752748 GO:0070840 dynein complex binding 1/123 24/18639 0.0416666666666667 6.3140243902439 0.147004431615562 0.41905808752748 GO:0015662 P-type ion transporter activity 1/123 25/18639 0.04 6.06146341463415 0.152640663413107 0.424589171609305 GO:0042974 nuclear retinoic acid receptor binding 1/123 25/18639 0.04 6.06146341463415 0.152640663413107 0.424589171609305 GO:0140358 P-type transmembrane transporter activity 1/123 25/18639 0.04 6.06146341463415 0.152640663413107 0.424589171609305 GO:0008066 glutamate receptor activity 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.424589171609305 GO:0008157 protein phosphatase 1 binding 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.424589171609305 GO:0008198 ferrous iron binding 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.424589171609305 GO:0052742 phosphatidylinositol kinase activity 1/123 26/18639 0.0384615384615385 5.82833020637899 0.158239954183505 0.424589171609305 GO:0004674 protein serine/threonine kinase activity 5/123 433/18639 0.0115473441108545 1.74984509660339 0.158592719358638 0.424589171609305 GO:0035255 ionotropic glutamate receptor binding 1/123 27/18639 0.037037037037037 5.61246612466125 0.163802544074195 0.424589171609305 GO:0003779 actin binding 5/123 443/18639 0.0112866817155756 1.71034520728954 0.169294757038835 0.424589171609305 GO:0036408 histone H3K14 acetyltransferase activity 1/123 28/18639 0.0357142857142857 5.41202090592335 0.169328671684279 0.424589171609305 GO:0051393 alpha-actinin binding 1/123 28/18639 0.0357142857142857 5.41202090592335 0.169328671684279 0.424589171609305 GO:0097718 disordered domain specific binding 1/123 28/18639 0.0357142857142857 5.41202090592335 0.169328671684279 0.424589171609305 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/123 29/18639 0.0344827586206897 5.22539949537426 0.174818574074416 0.424589171609305 GO:0010484 histone H3 acetyltransferase activity 1/123 29/18639 0.0344827586206897 5.22539949537426 0.174818574074416 0.424589171609305 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/123 29/18639 0.0344827586206897 5.22539949537426 0.174818574074416 0.424589171609305 GO:0097472 cyclin-dependent protein kinase activity 1/123 29/18639 0.0344827586206897 5.22539949537426 0.174818574074416 0.424589171609305 GO:0099604 ligand-gated calcium channel activity 1/123 29/18639 0.0344827586206897 5.22539949537426 0.174818574074416 0.424589171609305 GO:0004842 ubiquitin-protein transferase activity 5/123 449/18639 0.0111358574610245 1.68748981476452 0.175850428526188 0.424589171609305 GO:0035401 histone H3Y41 kinase activity 2/123 115/18639 0.0173913043478261 2.63541887592789 0.175952986765281 0.424589171609305 GO:0140801 histone H2AXY142 kinase activity 2/123 115/18639 0.0173913043478261 2.63541887592789 0.175952986765281 0.424589171609305 GO:0001968 fibronectin binding 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424589171609305 GO:0031624 ubiquitin conjugating enzyme binding 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424589171609305 GO:0033612 receptor serine/threonine kinase binding 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424589171609305 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424589171609305 GO:0043995 histone H4K5 acetyltransferase activity 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424589171609305 GO:0043996 histone H4K8 acetyltransferase activity 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424589171609305 GO:0043997 histone H4K12 acetyltransferase activity 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424589171609305 GO:0070566 adenylyltransferase activity 1/123 30/18639 0.0333333333333333 5.05121951219512 0.180272486776664 0.424589171609305 GO:0017147 Wnt-protein binding 1/123 31/18639 0.032258064516129 4.8882769472856 0.185690643804257 0.424589171609305 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/123 32/18639 0.03125 4.73551829268293 0.191073277661312 0.424589171609305 GO:0043425 bHLH transcription factor binding 1/123 32/18639 0.03125 4.73551829268293 0.191073277661312 0.424589171609305 GO:0051059 NF-kappaB binding 1/123 32/18639 0.03125 4.73551829268293 0.191073277661312 0.424589171609305 GO:0140416 transcription regulator inhibitor activity 1/123 33/18639 0.0303030303030303 4.5920177383592 0.196420619352485 0.424589171609305 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/123 349/18639 0.0114613180515759 1.73680900132784 0.199438424140814 0.424589171609305 GO:0030332 cyclin binding 1/123 34/18639 0.0294117647058824 4.45695839311334 0.201732898392561 0.424589171609305 GO:0061630 ubiquitin protein ligase activity 4/123 353/18639 0.0113314447592068 1.717128446072 0.204870521388573 0.424589171609305 GO:0031490 chromatin DNA binding 2/123 128/18639 0.015625 2.36775914634146 0.206957139378894 0.424589171609305 GO:0000175 3'-5'-RNA exonuclease activity 1/123 35/18639 0.0285714285714286 4.32961672473868 0.20701034281598 0.424589171609305 GO:0005154 epidermal growth factor receptor binding 1/123 35/18639 0.0285714285714286 4.32961672473868 0.20701034281598 0.424589171609305 GO:0010485 histone H4 acetyltransferase activity 1/123 35/18639 0.0285714285714286 4.32961672473868 0.20701034281598 0.424589171609305 GO:0016229 steroid dehydrogenase activity 1/123 35/18639 0.0285714285714286 4.32961672473868 0.20701034281598 0.424589171609305 GO:0034061 DNA polymerase activity 1/123 35/18639 0.0285714285714286 4.32961672473868 0.20701034281598 0.424589171609305 GO:0019787 ubiquitin-like protein transferase activity 5/123 479/18639 0.0104384133611691 1.58180151738887 0.210009291121918 0.424589171609305 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/123 36/18639 0.0277777777777778 4.20934959349593 0.212253179186311 0.424589171609305 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/123 36/18639 0.0277777777777778 4.20934959349593 0.212253179186311 0.424589171609305 GO:0045505 dynein intermediate chain binding 1/123 36/18639 0.0277777777777778 4.20934959349593 0.212253179186311 0.424589171609305 GO:0005539 glycosaminoglycan binding 3/123 242/18639 0.012396694214876 1.87855271114695 0.214814133073012 0.424589171609305 GO:0106310 protein serine kinase activity 4/123 361/18639 0.0110803324099723 1.6790757381258 0.2158642065524 0.424589171609305 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/123 243/18639 0.0123456790123457 1.87082204155375 0.216531877405797 0.424589171609305 GO:0042805 actinin binding 1/123 37/18639 0.027027027027027 4.09558338826632 0.217461632605656 0.424589171609305 GO:0042578 phosphoric ester hydrolase activity 4/123 363/18639 0.0110192837465565 1.66982463213062 0.21863829341773 0.424589171609305 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0004711 ribosomal protein S6 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0035175 histone H3S10 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0035979 histone H2AXS139 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0044022 histone H3S28 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0044023 histone H4S1 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0044024 histone H2AS1 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0044025 histone H2BS14 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0072354 histone H3T3 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0072371 histone H2AS121 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0140823 histone H2BS36 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0140855 histone H3S57 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0140995 histone H2A kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0140997 histone H4 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0140998 histone H2B kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:1990244 histone H2AT120 kinase activity 3/123 245/18639 0.0122448979591837 1.855550024888 0.21997618302908 0.424589171609305 GO:0004677 DNA-dependent protein kinase activity 3/123 246/18639 0.0121951219512195 1.84800713860797 0.221702636216109 0.424589171609305 GO:0140857 histone H3T45 kinase activity 3/123 246/18639 0.0121951219512195 1.84800713860797 0.221702636216109 0.424589171609305 GO:0005109 frizzled binding 1/123 38/18639 0.0263157894736842 3.98780487804878 0.222635926724004 0.424589171609305 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/123 38/18639 0.0263157894736842 3.98780487804878 0.222635926724004 0.424589171609305 GO:0042162 telomeric DNA binding 1/123 38/18639 0.0263157894736842 3.98780487804878 0.222635926724004 0.424589171609305 GO:0035402 histone H3T11 kinase activity 3/123 247/18639 0.0121457489878543 1.84052532833021 0.223431884570415 0.424589171609305 GO:0035403 histone H3T6 kinase activity 3/123 247/18639 0.0121457489878543 1.84052532833021 0.223431884570415 0.424589171609305 GO:0004679 AMP-activated protein kinase activity 3/123 248/18639 0.0120967741935484 1.8331038552321 0.225163874522718 0.424589171609305 GO:0002020 protease binding 2/123 136/18639 0.0147058823529412 2.22847919655667 0.226318601723411 0.424589171609305 GO:0016779 nucleotidyltransferase activity 2/123 136/18639 0.0147058823529412 2.22847919655667 0.226318601723411 0.424589171609305 GO:0140789 histone phosphatase activity 2/123 136/18639 0.0147058823529412 2.22847919655667 0.226318601723411 0.424589171609305 GO:0016755 aminoacyltransferase activity 5/123 496/18639 0.0100806451612903 1.52758654602675 0.230270297204099 0.427322078537911 GO:0061659 ubiquitin-like protein ligase activity 4/123 372/18639 0.010752688172043 1.6294256490952 0.231239930629279 0.427322078537911 GO:0004532 RNA exonuclease activity 1/123 40/18639 0.025 3.78841463414634 0.232882924452759 0.427322078537911 GO:0030331 nuclear estrogen receptor binding 1/123 40/18639 0.025 3.78841463414634 0.232882924452759 0.427322078537911 GO:0071855 neuropeptide receptor binding 1/123 40/18639 0.025 3.78841463414634 0.232882924452759 0.427322078537911 GO:0070851 growth factor receptor binding 2/123 139/18639 0.0143884892086331 2.18038252324969 0.23361571491822 0.427322078537911 GO:0019887 protein kinase regulator activity 3/123 255/18639 0.0117647058823529 1.78278335724534 0.237360111035713 0.428125876777055 GO:0001727 lipid kinase activity 1/123 41/18639 0.024390243902439 3.69601427721594 0.23795606818588 0.428125876777055 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/123 41/18639 0.024390243902439 3.69601427721594 0.23795606818588 0.428125876777055 GO:0042169 SH2 domain binding 1/123 41/18639 0.024390243902439 3.69601427721594 0.23795606818588 0.428125876777055 GO:0004402 histone acetyltransferase activity 1/123 42/18639 0.0238095238095238 3.60801393728223 0.242995932881715 0.431883459656165 GO:0008307 structural constituent of muscle 1/123 42/18639 0.0238095238095238 3.60801393728223 0.242995932881715 0.431883459656165 GO:0042056 chemoattractant activity 1/123 42/18639 0.0238095238095238 3.60801393728223 0.242995932881715 0.431883459656165 GO:0019903 protein phosphatase binding 2/123 144/18639 0.0138888888888889 2.10467479674797 0.245807982163385 0.435119774877927 GO:0008200 ion channel inhibitor activity 1/123 43/18639 0.0232558139534884 3.5241066364152 0.24800273506785 0.437241769858578 GO:0016248 channel inhibitor activity 1/123 44/18639 0.0227272727272727 3.4440133037694 0.252976689874617 0.440326544843939 GO:0043014 alpha-tubulin binding 1/123 44/18639 0.0227272727272727 3.4440133037694 0.252976689874617 0.440326544843939 GO:0015085 calcium ion transmembrane transporter activity 2/123 147/18639 0.0136054421768707 2.06172224987556 0.253136183388148 0.440326544843939 GO:0046915 transition metal ion transmembrane transporter activity 1/123 45/18639 0.0222222222222222 3.36747967479675 0.257918011044041 0.440326544843939 GO:0051539 4 iron, 4 sulfur cluster binding 1/123 45/18639 0.0222222222222222 3.36747967479675 0.257918011044041 0.440326544843939 GO:0140303 intramembrane lipid transporter activity 1/123 45/18639 0.0222222222222222 3.36747967479675 0.257918011044041 0.440326544843939 GO:0141110 transporter inhibitor activity 1/123 45/18639 0.0222222222222222 3.36747967479675 0.257918011044041 0.440326544843939 GO:0030291 protein serine/threonine kinase inhibitor activity 1/123 46/18639 0.0217391304347826 3.29427359490986 0.262826910938715 0.440326544843939 GO:0000510 H3-H4 histone complex chaperone activity 2/123 151/18639 0.0132450331125828 2.00710709093846 0.262915537113241 0.440326544843939 GO:0140584 chromatin extrusion motor activity 2/123 151/18639 0.0132450331125828 2.00710709093846 0.262915537113241 0.440326544843939 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/123 151/18639 0.0132450331125828 2.00710709093846 0.262915537113241 0.440326544843939 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/123 151/18639 0.0132450331125828 2.00710709093846 0.262915537113241 0.440326544843939 GO:0015616 DNA translocase activity 2/123 152/18639 0.0131578947368421 1.99390243902439 0.265361129532332 0.440326544843939 GO:0140674 ATP-dependent histone chaperone activity 2/123 152/18639 0.0131578947368421 1.99390243902439 0.265361129532332 0.440326544843939 GO:0001784 phosphotyrosine residue binding 1/123 47/18639 0.0212765957446809 3.22418266735859 0.267703600550641 0.440326544843939 GO:0061733 protein-lysine-acetyltransferase activity 1/123 47/18639 0.0212765957446809 3.22418266735859 0.267703600550641 0.440326544843939 GO:0140938 histone H3 methyltransferase activity 1/123 47/18639 0.0212765957446809 3.22418266735859 0.267703600550641 0.440326544843939 GO:0061775 cohesin loader activity 2/123 153/18639 0.0130718954248366 1.98087039693926 0.267806805178432 0.440326544843939 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/123 48/18639 0.0208333333333333 3.15701219512195 0.272548289509993 0.441873533922411 GO:0032266 phosphatidylinositol-3-phosphate binding 1/123 48/18639 0.0208333333333333 3.15701219512195 0.272548289509993 0.441873533922411 GO:0140693 molecular condensate scaffold activity 1/123 48/18639 0.0208333333333333 3.15701219512195 0.272548289509993 0.441873533922411 GO:1901681 sulfur compound binding 3/123 275/18639 0.0109090909090909 1.65312638580931 0.272773867182172 0.441873533922411 GO:0001222 transcription corepressor binding 1/123 49/18639 0.0204081632653061 3.09258337481334 0.277361186093839 0.447652796673511 GO:0140658 ATP-dependent chromatin remodeler activity 2/123 158/18639 0.0126582278481013 1.91818462488422 0.280032744449464 0.450087358693334 GO:0003689 DNA clamp loader activity 2/123 160/18639 0.0125 1.89420731707317 0.284920072432399 0.450087358693334 GO:0099106 ion channel regulator activity 2/123 160/18639 0.0125 1.89420731707317 0.284920072432399 0.450087358693334 GO:0005010 insulin-like growth factor receptor activity 1/123 51/18639 0.0196078431372549 2.9713055954089 0.286892428529658 0.450087358693334 GO:0005272 sodium channel activity 1/123 51/18639 0.0196078431372549 2.9713055954089 0.286892428529658 0.450087358693334 GO:0031267 small GTPase binding 3/123 283/18639 0.0106007067137809 1.60639489787124 0.287110002815143 0.450087358693334 GO:0004866 endopeptidase inhibitor activity 2/123 161/18639 0.0124223602484472 1.88244205423421 0.287362686141445 0.450087358693334 GO:0005080 protein kinase C binding 1/123 52/18639 0.0192307692307692 2.91416510318949 0.291611184247909 0.450087358693334 GO:0019207 kinase regulator activity 3/123 287/18639 0.0104529616724739 1.58400611880683 0.294302539369918 0.450087358693334 GO:0140713 histone chaperone activity 2/123 164/18639 0.0121951219512195 1.84800713860797 0.294685177489524 0.450087358693334 GO:0004864 protein phosphatase inhibitor activity 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.450087358693334 GO:0005246 calcium channel regulator activity 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.450087358693334 GO:0005544 calcium-dependent phospholipid binding 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.450087358693334 GO:0017046 peptide hormone binding 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.450087358693334 GO:0034212 protein N-acetyltransferase activity 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.450087358693334 GO:0140296 general transcription initiation factor binding 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.450087358693334 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/123 53/18639 0.0188679245283019 2.8591808559595 0.296298967340258 0.450087358693334 GO:0015485 cholesterol binding 1/123 54/18639 0.0185185185185185 2.80623306233062 0.300955979447067 0.454019501640077 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/123 54/18639 0.0185185185185185 2.80623306233062 0.300955979447067 0.454019501640077 GO:0016247 channel regulator activity 2/123 168/18639 0.0119047619047619 1.80400696864111 0.304432560843958 0.457691418529102 GO:0030414 peptidase inhibitor activity 2/123 169/18639 0.0118343195266272 1.79333237119353 0.306865962007896 0.459775280960635 GO:0141108 transporter regulator activity 2/123 170/18639 0.0117647058823529 1.78278335724534 0.30929781120181 0.460028234612915 GO:0019212 phosphatase inhibitor activity 1/123 56/18639 0.0178571428571429 2.70601045296167 0.310178490764061 0.460028234612915 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/123 56/18639 0.0178571428571429 2.70601045296167 0.310178490764061 0.460028234612915 GO:0008408 3'-5' exonuclease activity 1/123 58/18639 0.0172413793103448 2.61269974768713 0.319280305432357 0.470669695401541 GO:0031625 ubiquitin protein ligase binding 3/123 302/18639 0.00993377483443709 1.50533031820384 0.32136292613401 0.470669695401541 GO:0004721 phosphoprotein phosphatase activity 2/123 175/18639 0.0114285714285714 1.73184668989547 0.321430844410885 0.470669695401541 GO:0001786 phosphatidylserine binding 1/123 59/18639 0.0169491525423729 2.56841670111616 0.323786441939101 0.470669695401541 GO:0015459 potassium channel regulator activity 1/123 59/18639 0.0169491525423729 2.56841670111616 0.323786441939101 0.470669695401541 GO:0045309 protein phosphorylated amino acid binding 1/123 59/18639 0.0169491525423729 2.56841670111616 0.323786441939101 0.470669695401541 GO:0001098 basal transcription machinery binding 1/123 60/18639 0.0166666666666667 2.52560975609756 0.328262990251345 0.470939387974969 GO:0001099 basal RNA polymerase II transcription machinery binding 1/123 60/18639 0.0166666666666667 2.52560975609756 0.328262990251345 0.470939387974969 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/123 60/18639 0.0166666666666667 2.52560975609756 0.328262990251345 0.470939387974969 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/123 60/18639 0.0166666666666667 2.52560975609756 0.328262990251345 0.470939387974969 GO:0015026 coreceptor activity 1/123 61/18639 0.0163934426229508 2.48420631747301 0.332710143068993 0.474219976647039 GO:0016836 hydro-lyase activity 1/123 61/18639 0.0163934426229508 2.48420631747301 0.332710143068993 0.474219976647039 GO:0022824 transmitter-gated monoatomic ion channel activity 1/123 63/18639 0.0158730158730159 2.40534262485482 0.341517026804608 0.483632176668461 GO:0022835 transmitter-gated channel activity 1/123 63/18639 0.0158730158730159 2.40534262485482 0.341517026804608 0.483632176668461 GO:0061135 endopeptidase regulator activity 2/123 184/18639 0.0108695652173913 1.64713679745493 0.343135240564341 0.484361320282141 GO:0051020 GTPase binding 3/123 315/18639 0.00952380952380952 1.44320557491289 0.344846883379047 0.485217249369877 GO:0140597 protein carrier chaperone 2/123 188/18639 0.0106382978723404 1.61209133367929 0.352714339834002 0.494701582067499 GO:0044389 ubiquitin-like protein ligase binding 3/123 322/18639 0.0093167701863354 1.41183154067566 0.357472103094091 0.498440586040303 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/123 67/18639 0.0149253731343284 2.26174008008737 0.358786389951562 0.498440586040303 GO:0042054 histone methyltransferase activity 1/123 67/18639 0.0149253731343284 2.26174008008737 0.358786389951562 0.498440586040303 GO:0005548 phospholipid transporter activity 1/123 68/18639 0.0147058823529412 2.22847919655667 0.363033066348071 0.499144148064546 GO:0030145 manganese ion binding 1/123 68/18639 0.0147058823529412 2.22847919655667 0.363033066348071 0.499144148064546 GO:0032934 sterol binding 1/123 68/18639 0.0147058823529412 2.22847919655667 0.363033066348071 0.499144148064546 GO:0002039 p53 binding 1/123 69/18639 0.0144927536231884 2.19618239660657 0.367251844703527 0.499144148064546 GO:0008080 N-acetyltransferase activity 1/123 69/18639 0.0144927536231884 2.19618239660657 0.367251844703527 0.499144148064546 GO:0016279 protein-lysine N-methyltransferase activity 1/123 69/18639 0.0144927536231884 2.19618239660657 0.367251844703527 0.499144148064546 GO:0098960 postsynaptic neurotransmitter receptor activity 1/123 69/18639 0.0144927536231884 2.19618239660657 0.367251844703527 0.499144148064546 GO:0016278 lysine N-methyltransferase activity 1/123 70/18639 0.0142857142857143 2.16480836236934 0.371442906798383 0.503282210137315 GO:0140299 molecular sensor activity 1/123 71/18639 0.0140845070422535 2.13431810374442 0.375606433238353 0.507357612897344 GO:0045296 cadherin binding 3/123 334/18639 0.00898203592814371 1.36110705418431 0.379038563041909 0.510423095630055 GO:0140097 catalytic activity, acting on DNA 3/123 336/18639 0.00892857142857143 1.35300522648084 0.382620192430734 0.513670533569089 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/123 73/18639 0.0136986301369863 2.07584363514868 0.383851595747947 0.513752593089478 GO:0051536 iron-sulfur cluster binding 1/123 76/18639 0.0131578947368421 1.99390243902439 0.396017270528124 0.525998091061719 GO:0005516 calmodulin binding 2/123 207/18639 0.00966183574879227 1.46412159773772 0.397498594238327 0.525998091061719 GO:0003724 RNA helicase activity 1/123 77/18639 0.012987012987013 1.96800760215394 0.400019310916264 0.525998091061719 GO:0051540 metal cluster binding 1/123 77/18639 0.012987012987013 1.96800760215394 0.400019310916264 0.525998091061719 GO:0019199 transmembrane receptor protein kinase activity 1/123 78/18639 0.0128205128205128 1.94277673545966 0.40399504762337 0.525998091061719 GO:0008094 ATP-dependent activity, acting on DNA 2/123 210/18639 0.00952380952380952 1.44320557491289 0.404445400247407 0.525998091061719 GO:0008186 ATP-dependent activity, acting on RNA 1/123 79/18639 0.0126582278481013 1.91818462488422 0.40794465212433 0.525998091061719 GO:0016835 carbon-oxygen lyase activity 1/123 79/18639 0.0126582278481013 1.91818462488422 0.40794465212433 0.525998091061719 GO:0048306 calcium-dependent protein binding 1/123 80/18639 0.0125 1.89420731707317 0.41186829478536 0.525998091061719 GO:0003712 transcription coregulator activity 4/123 495/18639 0.00808080808080808 1.22453806356245 0.413224424182865 0.525998091061719 GO:0030971 receptor tyrosine kinase binding 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.525998091061719 GO:0033192 calmodulin-dependent protein phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.525998091061719 GO:0140791 histone H2AXS140 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.525998091061719 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.525998091061719 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.525998091061719 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.525998091061719 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.525998091061719 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.525998091061719 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/123 81/18639 0.0123456790123457 1.87082204155375 0.415766144871108 0.525998091061719 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/123 82/18639 0.0121951219512195 1.84800713860797 0.419638370551723 0.527854569261336 GO:0033549 MAP kinase phosphatase activity 1/123 82/18639 0.0121951219512195 1.84800713860797 0.419638370551723 0.527854569261336 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/123 83/18639 0.0120481927710843 1.82574199235968 0.42348513890987 0.531171359946951 GO:0004527 exonuclease activity 1/123 84/18639 0.0119047619047619 1.80400696864111 0.427306615947706 0.532919330684781 GO:0017018 myosin phosphatase activity 1/123 84/18639 0.0119047619047619 1.80400696864111 0.427306615947706 0.532919330684781 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/123 86/18639 0.0116279069767442 1.7620533182076 0.434874354710062 0.539293338185641 GO:0016209 antioxidant activity 1/123 86/18639 0.0116279069767442 1.7620533182076 0.434874354710062 0.539293338185641 GO:0004197 cysteine-type endopeptidase activity 1/123 88/18639 0.0113636363636364 1.7220066518847 0.442342893508098 0.547009944366352 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/123 89/18639 0.0112359550561798 1.70265826253768 0.446040366641541 0.548492215562006 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/123 89/18639 0.0112359550561798 1.70265826253768 0.446040366641541 0.548492215562006 GO:0140793 histone H2AXY142 phosphatase activity 1/123 90/18639 0.0111111111111111 1.68373983739837 0.449713522161923 0.551464347008615 GO:0072341 modified amino acid binding 1/123 91/18639 0.010989010989011 1.66523720182257 0.453362518699423 0.554390378019628 GO:0043178 alcohol binding 1/123 92/18639 0.0108695652173913 1.64713679745493 0.456987513857929 0.55727088495453 GO:0051219 phosphoprotein binding 1/123 93/18639 0.010752688172043 1.6294256490952 0.460588664221625 0.560106436546519 GO:0016410 N-acyltransferase activity 1/123 94/18639 0.0106382978723404 1.61209133367929 0.464166125361534 0.561346911938604 GO:0042562 hormone binding 1/123 94/18639 0.0106382978723404 1.61209133367929 0.464166125361534 0.561346911938604 GO:0008276 protein methyltransferase activity 1/123 95/18639 0.0105263157894737 1.59512195121951 0.467720051842015 0.564090941644628 GO:0016407 acetyltransferase activity 1/123 96/18639 0.0104166666666667 1.57850609756098 0.47125059722723 0.566791814199326 GO:0030594 neurotransmitter receptor activity 1/123 97/18639 0.0103092783505155 1.56223283882323 0.474757914087558 0.568965597855343 GO:0004725 protein tyrosine phosphatase activity 1/123 98/18639 0.0102040816326531 1.54629168740667 0.478242154005972 0.568965597855343 GO:0008170 N-methyltransferase activity 1/123 98/18639 0.0102040816326531 1.54629168740667 0.478242154005972 0.568965597855343 GO:0042626 ATPase-coupled transmembrane transporter activity 1/123 98/18639 0.0102040816326531 1.54629168740667 0.478242154005972 0.568965597855343 GO:0140104 molecular carrier activity 2/123 249/18639 0.00803212851405622 1.21716132823979 0.490941447875609 0.58212032078898 GO:0015171 amino acid transmembrane transporter activity 1/123 102/18639 0.00980392156862745 1.48565279770445 0.491951341714605 0.58212032078898 GO:0004722 protein serine/threonine phosphatase activity 1/123 103/18639 0.00970873786407767 1.4712289841345 0.49532243655029 0.584533735606391 GO:0003713 transcription coactivator activity 2/123 256/18639 0.0078125 1.18387957317073 0.505633258383563 0.595101877829449 GO:0019888 protein phosphatase regulator activity 1/123 107/18639 0.00934579439252336 1.41622976977433 0.508586381398783 0.59697706265793 GO:0005496 steroid binding 1/123 108/18639 0.00925925925925926 1.40311653116531 0.511847976212508 0.599203364152776 GO:0003730 mRNA 3'-UTR binding 2/123 262/18639 0.00763358778625954 1.15676782722026 0.518008379903652 0.604802337174743 GO:1902936 phosphatidylinositol bisphosphate binding 1/123 111/18639 0.00900900900900901 1.36519446275544 0.521504483130596 0.605805098085976 GO:0016887 ATP hydrolysis activity 3/123 417/18639 0.00719424460431655 1.09019126162485 0.521627168739177 0.605805098085976 GO:0001221 transcription coregulator binding 1/123 115/18639 0.00869565217391304 1.31770943796394 0.534085687235527 0.618637511072286 GO:0016791 phosphatase activity 2/123 273/18639 0.00732600732600733 1.11015813454838 0.540162018395866 0.62086630579376 GO:0019208 phosphatase regulator activity 1/123 117/18639 0.00854700854700855 1.29518449030644 0.540252685223728 0.62086630579376 GO:1990782 protein tyrosine kinase binding 1/123 117/18639 0.00854700854700855 1.29518449030644 0.540252685223728 0.62086630579376 GO:0022853 active monoatomic ion transmembrane transporter activity 1/123 118/18639 0.00847457627118644 1.28420835055808 0.543305752911746 0.622744714172994 GO:0003697 single-stranded DNA binding 1/123 121/18639 0.00826446280991736 1.25236847409796 0.552344815210824 0.629816555526108 GO:0004540 RNA nuclease activity 1/123 121/18639 0.00826446280991736 1.25236847409796 0.552344815210824 0.629816555526108 GO:0030246 carbohydrate binding 2/123 280/18639 0.00714285714285714 1.08240418118467 0.553893668680181 0.629934626422223 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/123 122/18639 0.00819672131147541 1.24210315873651 0.555318224203645 0.629934626422223 GO:0005267 potassium channel activity 1/123 124/18639 0.00806451612903226 1.2220692368214 0.561206398935956 0.634973219414652 GO:0019783 ubiquitin-like protein peptidase activity 1/123 127/18639 0.0078740157480315 1.19320145957365 0.569893960805733 0.641496022547992 GO:0042826 histone deacetylase binding 1/123 127/18639 0.0078740157480315 1.19320145957365 0.569893960805733 0.641496022547992 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/123 128/18639 0.0078125 1.18387957317073 0.572751731053188 0.643063964021355 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/123 130/18639 0.00769230769230769 1.1656660412758 0.578410890758496 0.647761176130051 GO:0005262 calcium channel activity 1/123 131/18639 0.00763358778625954 1.15676782722026 0.581212525662419 0.649048377685362 GO:0005179 hormone activity 1/123 132/18639 0.00757575757575758 1.1480044345898 0.583995692905964 0.649048377685362 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/123 132/18639 0.00757575757575758 1.1480044345898 0.583995692905964 0.649048377685362 GO:0051087 protein-folding chaperone binding 1/123 134/18639 0.00746268656716418 1.13087004004368 0.589507106600156 0.653519241912799 GO:0099094 ligand-gated monoatomic cation channel activity 1/123 136/18639 0.00735294117647059 1.11423959827834 0.594946088418298 0.657887488200586 GO:0016922 nuclear receptor binding 1/123 137/18639 0.0072992700729927 1.10610646252448 0.597638712918354 0.659204509977783 GO:0005506 iron ion binding 1/123 154/18639 0.00649350649350649 0.984003801076972 0.640789327807056 0.705028859416786 GO:0004386 helicase activity 1/123 155/18639 0.00645161290322581 0.97765538945712 0.643179531360193 0.705889535667812 GO:0015079 potassium ion transmembrane transporter activity 1/123 160/18639 0.00625 0.947103658536585 0.654895963657532 0.71695593028842 GO:0008083 growth factor activity 1/123 162/18639 0.00617283950617284 0.935411020776874 0.659474963259771 0.720172907639402 GO:0005261 monoatomic cation channel activity 2/123 341/18639 0.00586510263929619 0.8887776267792 0.661229318623836 0.720296950064179 GO:0015081 sodium ion transmembrane transporter activity 1/123 164/18639 0.00609756097560976 0.924003569303986 0.663993694028948 0.721517900194822 GO:0015399 primary active transmembrane transporter activity 1/123 166/18639 0.00602409638554217 0.912870996179841 0.668452942806813 0.724569979980718 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/123 167/18639 0.00598802395209581 0.907404702789543 0.670660504547448 0.725172318956477 GO:0005319 lipid transporter activity 1/123 178/18639 0.00561797752808989 0.851329131268841 0.694002109348293 0.748567385758969 GO:0015276 ligand-gated monoatomic ion channel activity 1/123 186/18639 0.00537634408602151 0.8147128245476 0.709939906807055 0.758920613252595 GO:0008234 cysteine-type peptidase activity 1/123 187/18639 0.0053475935828877 0.810356071475153 0.711873326384508 0.758920613252595 GO:0031406 carboxylic acid binding 1/123 187/18639 0.0053475935828877 0.810356071475153 0.711873326384508 0.758920613252595 GO:0022834 ligand-gated channel activity 1/123 188/18639 0.00531914893617021 0.806045666839647 0.713793962676222 0.758920613252595 GO:0046943 carboxylic acid transmembrane transporter activity 1/123 188/18639 0.00531914893617021 0.806045666839647 0.713793962676222 0.758920613252595 GO:0005342 organic acid transmembrane transporter activity 1/123 189/18639 0.00529100529100529 0.801780874951607 0.715701899513836 0.758920613252595 GO:0043177 organic acid binding 1/123 189/18639 0.00529100529100529 0.801780874951607 0.715701899513836 0.758920613252595 GO:0140098 catalytic activity, acting on RNA 2/123 387/18639 0.00516795865633075 0.783134808092267 0.727820805626862 0.769911647398054 GO:0016829 lyase activity 1/123 200/18639 0.005 0.757682926829268 0.735874477788033 0.776559845550353 GO:0008168 methyltransferase activity 1/123 204/18639 0.00490196078431373 0.742826398852224 0.742852384366841 0.782043637259097 GO:0004518 nuclease activity 1/123 209/18639 0.00478468899521531 0.725055432372505 0.751318139578125 0.787180580608107 GO:0051015 actin filament binding 1/123 209/18639 0.00478468899521531 0.725055432372505 0.751318139578125 0.787180580608107 GO:0016741 transferase activity, transferring one-carbon groups 1/123 215/18639 0.00465116279069767 0.70482132728304 0.761112838393908 0.795544133464109 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/123 229/18639 0.00436681222707424 0.661731813824688 0.782504171753853 0.815538512362013 GO:0000287 magnesium ion binding 1/123 230/18639 0.00434782608695652 0.658854718981972 0.783957294343439 0.815538512362013 GO:0005125 cytokine activity 1/123 234/18639 0.00427350427350427 0.647592245153221 0.789674114409444 0.819543584458028 GO:0005216 monoatomic ion channel activity 2/123 448/18639 0.00446428571428571 0.676502613240418 0.798873236510441 0.82713526138699 GO:0046873 metal ion transmembrane transporter activity 2/123 450/18639 0.00444444444444444 0.67349593495935 0.800900318557651 0.827282917286609 GO:0033218 amide binding 1/123 247/18639 0.00404858299595142 0.613508442776736 0.807237382751568 0.831871387389526 GO:0016757 glycosyltransferase activity 1/123 267/18639 0.00374531835205993 0.567552754179227 0.831457691872845 0.854824184384494 GO:0008514 organic anion transmembrane transporter activity 1/123 269/18639 0.00371747211895911 0.563333031099828 0.833706969972034 0.855134018265708 GO:0005126 cytokine receptor binding 1/123 275/18639 0.00363636363636364 0.551042128603104 0.840277701911511 0.859864594729961 GO:0022836 gated channel activity 1/123 318/18639 0.00314465408805031 0.476530142659917 0.880403140657363 0.898830183136238 GO:0030371 translation repressor activity 1/123 329/18639 0.00303951367781155 0.46059752390837 0.888946997384175 0.904862384317346 GO:0003924 GTPase activity 1/123 331/18639 0.00302114803625378 0.457814457298652 0.890434054726864 0.904862384317346 GO:0045182 translation regulator activity 1/123 356/18639 0.00280898876404494 0.42566456563442 0.90743699331295 0.920011177977794 GO:0005525 GTP binding 1/123 378/18639 0.00264550264550265 0.400890437475803 0.920218035314144 0.93081962558274 GO:0015631 tubulin binding 1/123 385/18639 0.0025974025974026 0.393601520430789 0.923905156728525 0.932400836330626 GO:0019001 guanyl nucleotide binding 1/123 400/18639 0.0025 0.378841463414634 0.931246636975345 0.935508635313904 GO:0032561 guanyl ribonucleotide binding 1/123 400/18639 0.0025 0.378841463414634 0.931246636975345 0.935508635313904 GO:0004175 endopeptidase activity 1/123 405/18639 0.00246913580246914 0.37416440831075 0.93353411792793 0.935665474361556 GO:0022804 active transmembrane transporter activity 1/123 457/18639 0.00218818380743982 0.331589902332284 0.953277202123229 0.953277202123229