category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
NA	NA	hsa04517	IgSF CAM signaling	4/21	299/9376	5.97292562509954	RASA1/NRCAM/GRIP1/NECTIN3	4.14047131366784
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	3/21	238/9376	5.62785114045618	RASA1/RASAL2/RALGAPA2	3.42622336408238
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/21	122/9376	7.31928181108509	CSHL1/PLCB1	3.32855916366954
Metabolism	Lipid metabolism	hsa00061	Fatty acid biosynthesis	1/21	18/9376	24.8042328042328	ACSL4	4.78930296451465
Metabolism	Metabolism of cofactors and vitamins	hsa00770	Pantothenate and CoA biosynthesis	1/21	21/9376	21.2607709750567	DPYD	4.40369374645126
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/21	160/9376	5.58095238095238	NRCAM/NECTIN3	2.76896792640301
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/21	178/9376	5.01658640984484	PLCB1/TBL1XR1	2.56326674210765
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	1/21	29/9376	15.3957307060755	STK3	3.67849340010513
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/21	187/9376	4.77514642220525	PLCB1/NAIP	2.47055125250684
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/21	31/9376	14.4024577572965	DPYD	3.54118838251741
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/21	37/9376	12.0669240669241	PLCB1	3.19558956354431
NA	NA	hsa04081	Hormone signaling	2/21	219/9376	4.07740813220265	CSHL1/PLCB1	2.18325235390177
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/21	41/9376	10.8896631823461	DAPK1	3.00669695463765
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/21	42/9376	10.6303854875283	ACSL4	2.96351962861283
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/21	43/9376	10.3831672203765	ACSL4	2.92177279248879
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/21	233/9376	3.83241365215614	DIAPH2/FBN2	2.07426227720053
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/21	48/9376	9.3015873015873	PLCB1	2.73187534728602
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/21	253/9376	3.52945605119518	PLCB1/NAIP	1.93237740557592
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/21	53/9376	8.4240790655885	PLCB1	2.56788795842803
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/21	56/9376	7.97278911564626	NAIP	2.47951064774318
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/21	57/9376	7.83291562238931	ACSL4	2.45150181660929
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/21	59/9376	7.56739305891848	DPYD	2.39747649130105
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/21	60/9376	7.44126984126984	PLCB1	2.37140520165786
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/21	63/9376	7.08692365835223	KMT2C	2.29666005959103
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/21	65/9376	6.86886446886447	PLCB1	2.24949993527613
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/21	65/9376	6.86886446886447	PLCB1	2.24949993527613
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/21	67/9376	6.6638237384506	PLCB1	2.20429139479852
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/21	69/9376	6.47066942719117	PLCB1	2.16089443367545
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/21	300/9376	2.97650793650794	RASA1/STK3	1.64848627622437
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/21	70/9376	6.37823129251701	ACSL4	2.1398353650039
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/21	73/9376	6.11611219830398	TRIM5	2.07904250991769
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/21	75/9376	5.95301587301587	PLCB1	2.04036995091541
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/21	76/9376	5.87468671679198	ACSL4	2.02155434787549
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/21	76/9376	5.87468671679198	PLCB1	2.02155434787549
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/21	78/9376	5.72405372405372	PLCB1	1.98490967235691
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/21	82/9376	5.44483159117305	DPYD	1.91528890356554
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/21	83/9376	5.37923121055651	ACSL4	1.89859504249501
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/21	85/9376	5.25266106442577	ADK	1.86600323980669
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/21	86/9376	5.19158361018826	PLCB1	1.85009015364762
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/21	86/9376	5.19158361018826	PLCB1	1.85009015364762
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/21	89/9376	5.01658640984484	PLCB1	1.80379751666147
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/21	93/9376	4.80081925243216	NECTIN3	1.74521085653402
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/21	93/9376	4.80081925243216	PLCB1	1.74521085653402
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/21	93/9376	4.80081925243216	PLCB1	1.74521085653402
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/21	97/9376	4.60284732449681	PLCB1	1.68987479403441
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/21	98/9376	4.555879494655	PLCB1	1.67651050140654
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/21	98/9376	4.555879494655	PLCB1	1.67651050140654
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/21	99/9376	4.50986050986051	PLCB1	1.66332481040169
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/21	101/9376	4.42055634134842	PLCB1	1.63747193649704
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/21	101/9376	4.42055634134842	PLCB1	1.63747193649704
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/21	102/9376	4.37721755368814	PLCB1	1.62479647307267
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/21	103/9376	4.33472029588534	PLCB1	1.61228303741094
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/21	103/9376	4.33472029588534	PLCB1	1.61228303741094
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/21	107/9376	4.17267467734757	PLCB1	1.56377541013263
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/21	115/9376	3.8824016563147	PLCB1	1.47349228537803
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/21	115/9376	3.8824016563147	PLCB1	1.47349228537803
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/21	115/9376	3.8824016563147	PLCB1	1.47349228537803
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/21	116/9376	3.84893267651888	PLCB1	1.46278021435655
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/21	122/9376	3.65964090554255	PLCB1	1.40091427679087
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/21	125/9376	3.57180952380952	PLCB1	1.37142750691253
Organismal Systems	Immune system	hsa04611	Platelet activation	1/21	126/9376	3.54346182917611	PLCB1	1.36179902910036
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/21	128/9376	3.48809523809524	ADK	1.34283132577905
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/21	130/9376	3.43443223443223	PLCB1	1.32423728351828
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/21	133/9376	3.35696383816685	PLCB1	1.29701695396797
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/21	134/9376	3.3319118692253	PLCB1	1.28811589604308
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/21	139/9376	3.21205892428914	PLCB1	1.244835627341
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/21	140/9376	3.1891156462585	PLCB1	1.23641467306172
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/21	144/9376	3.1005291005291	PLCB1	1.20347047577224
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/21	149/9376	2.9964844998402	PLCB1	1.16386392311507
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/21	149/9376	2.9964844998402	PLCB1	1.16386392311507
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/21	154/9376	2.89919604205318	PLCB1	1.12587710481668
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/21	154/9376	2.89919604205318	PLCB1	1.12587710481668
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/21	155/9376	2.88049155145929	PLCB1	1.11846298092167
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/21	157/9376	2.84379739156809	GULP1	1.10381045839505
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/21	157/9376	2.84379739156809	STK3	1.10381045839505
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/21	166/9376	2.68961560527826	PLCB1	1.04060409494816
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/21	168/9376	2.65759637188209	CSHL1	1.0271270403462
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/21	169/9376	2.64187094956326	DAPK1	1.02046165234432
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/21	184/9376	2.42650103519669	RASA1	0.925868661460049
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/21	193/9376	2.31334813718233	PLCB1	0.873453148048701
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/21	195/9376	2.28962148962149	PLCB1	0.862199889833102
NA	NA	hsa04082	Neuroactive ligand signaling	1/21	199/9376	2.24359894711653	PLCB1	0.840097916597869
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/21	200/9376	2.23238095238095	NAIP	0.834654352198917
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/21	201/9376	2.22127457948353	AFF1	0.829242780845132
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/21	205/9376	2.17793263646922	PLCB1	0.807908966646118
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/21	212/9376	2.10601976639712	PLCB1	0.771723398996141
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/21	214/9376	2.08633733867379	TRIM5	0.761640167026066
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/21	216/9376	2.06701940035273	PLCB1	0.751665892413924
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/21	227/9376	1.96685546465282	PLCB1	0.698652247769715
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/21	232/9376	1.92446633825944	DIAPH2	0.675523365972371
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/21	235/9376	1.89989868287741	ACSL4	0.661917834112373
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/21	248/9376	1.80030721966206	NAIP	0.605157122403723
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/21	254/9376	1.75778027746532	PLCB1	0.580080827740395
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/21	298/9376	1.4982422499201	CSHL1	0.414120742991803
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	1/21	308/9376	1.44959802102659	PLCB1	0.380117078863313
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/21	362/9376	1.23335964219942	CSHL1	0.21453326791502
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/21	370/9376	1.20669240669241	CSHL1	0.192190892031994
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/21	388/9376	1.1507118311242	PLCB1	0.143649813686528
NA	NA	hsa04519	Cadherin signaling	1/21	404/9376	1.10513908533711	STK3	0.102349007195253
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	1/21	480/9376	0.93015873015873	PLCB1	-0.0744232700292668