ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005096 GTPase activator activity 15/284 271/18639 0.0553505535055351 3.63267241827348 1.8868464745312e-05 0.00488958358356858 GO:0030695 GTPase regulator activity 21/284 489/18639 0.0429447852760736 2.81847835479133 2.11173574230014e-05 0.00488958358356858 GO:0060589 nucleoside-triphosphatase regulator activity 21/284 490/18639 0.0428571428571429 2.81272635814889 2.1763725149415e-05 0.00488958358356858 GO:0061980 regulatory RNA binding 6/284 58/18639 0.103448275862069 6.78933948518698 0.00024712416410631 0.0416404216519133 GO:0035198 miRNA binding 5/284 42/18639 0.119047619047619 7.81312877263581 0.000425144895105686 0.0573095318602464 GO:0045295 gamma-catenin binding 3/284 12/18639 0.25 16.4075704225352 0.000695431592427042 0.0781201488826377 GO:0031994 insulin-like growth factor I binding 3/284 13/18639 0.230769230769231 15.1454496208017 0.000893904261044676 0.0860702102777302 GO:0005545 1-phosphatidylinositol binding 3/284 14/18639 0.214285714285714 14.0636317907445 0.0011249242154353 0.0947748651504238 GO:0070851 growth factor receptor binding 8/284 139/18639 0.0575539568345324 3.77728239943257 0.00132658172855417 0.0993462316717233 GO:0003712 transcription coregulator activity 17/284 495/18639 0.0343434343434343 2.25396927016645 0.00162037039487465 0.109212964614551 GO:0005154 epidermal growth factor receptor binding 4/284 35/18639 0.114285714285714 7.50060362173038 0.00190487699677652 0.116717008711579 GO:0005520 insulin-like growth factor binding 3/284 19/18639 0.157894736842105 10.362676056338 0.00283064619327804 0.158987961189116 GO:0035613 RNA stem-loop binding 3/284 21/18639 0.142857142857143 9.37575452716298 0.00379887907451876 0.196957268940434 GO:0140517 protein-RNA adaptor activity 3/284 22/18639 0.136363636363636 8.94958386683739 0.00434961862299328 0.209403067992677 GO:0030276 clathrin binding 4/284 46/18639 0.0869565217391304 5.70698101653399 0.00520950505962706 0.234080427345909 GO:0050699 WW domain binding 3/284 24/18639 0.125 8.20378521126761 0.00558991911442251 0.235475342695048 GO:0003713 transcription coactivator activity 10/284 256/18639 0.0390625 2.56368287852113 0.00606608769435808 0.240502535646903 GO:0050750 low-density lipoprotein particle receptor binding 3/284 26/18639 0.115384615384615 7.57272481040087 0.00702179347471737 0.249434516157708 GO:0008266 poly(U) RNA binding 3/284 27/18639 0.111111111111111 7.29225352112676 0.00781171011467098 0.249434516157708 GO:0017046 peptide hormone binding 4/284 53/18639 0.0754716981132075 4.95322880680308 0.00860564503028282 0.249434516157708 GO:0051020 GTPase binding 11/284 315/18639 0.0349206349206349 2.29185110663984 0.00921799494517998 0.249434516157708 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/284 29/18639 0.103448275862069 6.78933948518698 0.00954314082008868 0.249434516157708 GO:0097472 cyclin-dependent protein kinase activity 3/284 29/18639 0.103448275862069 6.78933948518698 0.00954314082008868 0.249434516157708 GO:0106310 protein serine kinase activity 12/284 361/18639 0.0332409972299169 2.18161601186064 0.00967935820688028 0.249434516157708 GO:0008187 poly-pyrimidine tract binding 3/284 30/18639 0.1 6.56302816901408 0.0104859031100097 0.249434516157708 GO:0070325 lipoprotein particle receptor binding 3/284 31/18639 0.0967741935483871 6.35131758291686 0.0114807527938996 0.249434516157708 GO:0032050 clathrin heavy chain binding 2/284 11/18639 0.181818181818182 11.9327784891165 0.0116202259137647 0.249434516157708 GO:0034056 estrogen response element binding 2/284 11/18639 0.181818181818182 11.9327784891165 0.0116202259137647 0.249434516157708 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/284 11/18639 0.181818181818182 11.9327784891165 0.0116202259137647 0.249434516157708 GO:0097493 structural molecule activity conferring elasticity 2/284 11/18639 0.181818181818182 11.9327784891165 0.0116202259137647 0.249434516157708 GO:0031267 small GTPase binding 10/284 283/18639 0.0353356890459364 2.31909122580003 0.0118083217794788 0.249434516157708 GO:0005178 integrin binding 7/284 161/18639 0.0434782608695652 2.85349050826699 0.0118425883042235 0.249434516157708 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/284 60/18639 0.0666666666666667 4.37535211267606 0.0131967600921862 0.250350884495932 GO:0005165 neurotrophin receptor binding 2/284 12/18639 0.166666666666667 10.9383802816901 0.0138051847780323 0.250350884495932 GO:0017166 vinculin binding 2/284 12/18639 0.166666666666667 10.9383802816901 0.0138051847780323 0.250350884495932 GO:0035497 cAMP response element binding 2/284 12/18639 0.166666666666667 10.9383802816901 0.0138051847780323 0.250350884495932 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/284 12/18639 0.166666666666667 10.9383802816901 0.0138051847780323 0.250350884495932 GO:0035591 signaling adaptor activity 6/284 129/18639 0.0465116279069767 3.0525712414019 0.0142162603125391 0.250350884495932 GO:0042562 hormone binding 5/284 94/18639 0.0531914893617021 3.49097243032664 0.0144861787764708 0.250350884495932 GO:0043130 ubiquitin binding 5/284 100/18639 0.05 3.28151408450704 0.0184736196235605 0.294461980735533 GO:0005161 platelet-derived growth factor receptor binding 2/284 14/18639 0.142857142857143 9.37575452716298 0.0186573180117655 0.294461980735533 GO:0019992 diacylglycerol binding 2/284 14/18639 0.142857142857143 9.37575452716298 0.0186573180117655 0.294461980735533 GO:0003779 actin binding 13/284 443/18639 0.0293453724604966 1.92594506088449 0.0187861501062729 0.294461980735533 GO:1990841 promoter-specific chromatin binding 4/284 68/18639 0.0588235294117647 3.8606048053024 0.0200658433914276 0.305648529189024 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/284 15/18639 0.133333333333333 8.75070422535211 0.0213137698395907 0.305648529189024 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/284 15/18639 0.133333333333333 8.75070422535211 0.0213137698395907 0.305648529189024 GO:0120283 protein serine/threonine kinase binding 2/284 15/18639 0.133333333333333 8.75070422535211 0.0213137698395907 0.305648529189024 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/284 40/18639 0.075 4.92227112676056 0.0228360047420945 0.32065556658691 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/284 16/18639 0.125 8.20378521126761 0.024116871794785 0.325095431793702 GO:0140328 floppase activity 2/284 16/18639 0.125 8.20378521126761 0.024116871794785 0.325095431793702 GO:0008307 structural constituent of muscle 3/284 42/18639 0.0714285714285714 4.68787726358149 0.0259542687837518 0.342239839186316 GO:0046982 protein heterodimerization activity 11/284 369/18639 0.029810298102981 1.95645826176572 0.0265372577497673 0.342239839186316 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/284 17/18639 0.117647058823529 7.72120961060481 0.0270615713146028 0.342239839186316 GO:0008375 acetylglucosaminyltransferase activity 3/284 43/18639 0.0697674418604651 4.57885686210285 0.0275946618411399 0.342239839186316 GO:0061659 ubiquitin-like protein ligase activity 11/284 372/18639 0.0295698924731183 1.94068037255793 0.0279275833163907 0.342239839186316 GO:0005200 structural constituent of cytoskeleton 5/284 112/18639 0.0446428571428571 2.92992328973843 0.0284730333315811 0.34269329402653 GO:0019205 nucleobase-containing compound kinase activity 3/284 44/18639 0.0681818181818182 4.47479193341869 0.0292890773073309 0.346330493072649 GO:0034185 apolipoprotein binding 2/284 18/18639 0.111111111111111 7.29225352112676 0.0301429348103631 0.350281690727323 GO:0140303 intramembrane lipid transporter activity 3/284 45/18639 0.0666666666666667 4.37535211267606 0.0310373546134476 0.3545623221943 GO:0045296 cadherin binding 10/284 334/18639 0.029940119760479 1.96497849371679 0.0326737454149533 0.362847321084546 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/284 46/18639 0.0652173913043478 4.28023576240049 0.0328392976055746 0.362847321084546 GO:1990782 protein tyrosine kinase binding 5/284 117/18639 0.0427350427350427 2.80471289274106 0.0334831121922127 0.363993832541151 GO:0004674 protein serine/threonine kinase activity 12/284 433/18639 0.0277136258660508 1.81885307224409 0.0342460811931654 0.366378709907833 GO:0001618 virus receptor activity 4/284 81/18639 0.0493827160493827 3.24100156494523 0.0352294761573806 0.371010420782414 GO:0140272 exogenous protein binding 4/284 82/18639 0.0487804878048781 3.20147715561663 0.0366087140468253 0.372740484339672 GO:0032182 ubiquitin-like protein binding 5/284 120/18639 0.0416666666666667 2.73459507042254 0.0367362091372705 0.372740484339672 GO:0140297 DNA-binding transcription factor binding 13/284 488/18639 0.0266393442622951 1.74834766797506 0.0370528374640327 0.372740484339672 GO:0001222 transcription corepressor binding 3/284 49/18639 0.0612244897959184 4.01818051164128 0.0385646572224435 0.382243808351867 GO:0005516 calmodulin binding 7/284 207/18639 0.0338164251207729 2.21938150642988 0.0396977400255119 0.385211337491636 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/284 21/18639 0.0952380952380952 6.25050301810865 0.0401594071365709 0.385211337491636 GO:0005006 epidermal growth factor receptor activity 3/284 50/18639 0.06 3.93781690140845 0.0405786423767154 0.385211337491636 GO:0008093 cytoskeletal anchor activity 2/284 22/18639 0.0909090909090909 5.96638924455826 0.0437403859879286 0.409458613275888 GO:0141003 histone H2AX kinase activity 10/284 354/18639 0.0282485875706215 1.8539627596085 0.0454760335585395 0.415248224925731 GO:0003727 single-stranded RNA binding 4/284 89/18639 0.0449438202247191 2.94967558157936 0.047125746414328 0.415248224925731 GO:0005158 insulin receptor binding 2/284 23/18639 0.0869565217391304 5.70698101653399 0.0474350619734518 0.415248224925731 GO:0017134 fibroblast growth factor binding 2/284 23/18639 0.0869565217391304 5.70698101653399 0.0474350619734518 0.415248224925731 GO:0140996 histone H3 kinase activity 10/284 357/18639 0.0280112044817927 1.83838324062019 0.0476529246520014 0.415248224925731 GO:0003730 mRNA 3'-UTR binding 8/284 262/18639 0.0305343511450382 2.00397806687453 0.0480554325581707 0.415248224925731 GO:0035173 histone kinase activity 10/284 360/18639 0.0277777777777778 1.82306338028169 0.0498990223572083 0.425720773022258 GO:0030552 cAMP binding 2/284 24/18639 0.0833333333333333 5.46919014084507 0.0512391658697272 0.426360466619705 GO:0035035 histone acetyltransferase binding 2/284 24/18639 0.0833333333333333 5.46919014084507 0.0512391658697272 0.426360466619705 GO:0051213 dioxygenase activity 4/284 93/18639 0.043010752688172 2.82280781462971 0.0538116399610434 0.432210582868812 GO:0003707 nuclear steroid receptor activity 2/284 25/18639 0.08 5.25042253521127 0.0551485313452787 0.432210582868812 GO:0015662 P-type ion transporter activity 2/284 25/18639 0.08 5.25042253521127 0.0551485313452787 0.432210582868812 GO:0017025 TBP-class protein binding 2/284 25/18639 0.08 5.25042253521127 0.0551485313452787 0.432210582868812 GO:0140358 P-type transmembrane transporter activity 2/284 25/18639 0.08 5.25042253521127 0.0551485313452787 0.432210582868812 GO:0019838 growth factor binding 5/284 136/18639 0.0367647058823529 2.412878003314 0.0572919457216036 0.443847947314492 GO:0008143 poly(A) binding 2/284 26/18639 0.0769230769230769 5.04848320693391 0.0591590928344921 0.44694399617419 GO:0043548 phosphatidylinositol 3-kinase binding 2/284 26/18639 0.0769230769230769 5.04848320693391 0.0591590928344921 0.44694399617419 GO:0004879 nuclear receptor activity 3/284 59/18639 0.0508474576271186 3.3371329672953 0.0610030647836264 0.44694399617419 GO:0005085 guanyl-nucleotide exchange factor activity 7/284 230/18639 0.0304347826086957 1.9974433557869 0.0629617856695647 0.44694399617419 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/284 27/18639 0.0740740740740741 4.86150234741784 0.0632668834520778 0.44694399617419 GO:0004713 protein tyrosine kinase activity 5/284 140/18639 0.0357142857142857 2.34393863179074 0.063282668455057 0.44694399617419 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/284 60/18639 0.05 3.28151408450704 0.0635191860831758 0.44694399617419 GO:0098531 ligand-modulated transcription factor activity 3/284 60/18639 0.05 3.28151408450704 0.0635191860831758 0.44694399617419 GO:0019787 ubiquitin-like protein transferase activity 12/284 479/18639 0.0250521920668058 1.64418242229998 0.0639637985284996 0.44694399617419 GO:1901981 phosphatidylinositol phosphate binding 6/284 185/18639 0.0324324324324324 2.128549676437 0.0643228006363449 0.44694399617419 GO:0015026 coreceptor activity 3/284 61/18639 0.0491803278688525 3.22771877164627 0.0660827025973246 0.454487158679559 GO:0019789 SUMO transferase activity 2/284 28/18639 0.0714285714285714 4.68787726358149 0.0674680329473359 0.459327820267721 GO:0043236 laminin binding 2/284 29/18639 0.0689655172413793 4.52622632345799 0.0717587656975024 0.483654080801166 GO:0001968 fibronectin binding 2/284 30/18639 0.0666666666666667 4.37535211267606 0.0761353987394662 0.490260608143768 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/284 30/18639 0.0666666666666667 4.37535211267606 0.0761353987394662 0.490260608143768 GO:0038024 cargo receptor activity 3/284 65/18639 0.0461538461538462 3.02908992416035 0.0767988029652327 0.490260608143768 GO:0016755 aminoacyltransferase activity 12/284 496/18639 0.0241935483870968 1.58782939572921 0.0782875179937876 0.490260608143768 GO:0000149 SNARE binding 4/284 106/18639 0.0377358490566038 2.47661440340154 0.0788655795302716 0.490260608143768 GO:0016758 hexosyltransferase activity 6/284 197/18639 0.0304568527918782 1.99889182812612 0.0814623665150037 0.490260608143768 GO:0016500 protein-hormone receptor activity 3/284 67/18639 0.0447761194029851 2.93866932940929 0.0824253489868833 0.490260608143768 GO:0050840 extracellular matrix binding 3/284 67/18639 0.0447761194029851 2.93866932940929 0.0824253489868833 0.490260608143768 GO:0070717 poly-purine tract binding 2/284 32/18639 0.0625 4.1018926056338 0.0851320855979432 0.490260608143768 GO:0071813 lipoprotein particle binding 2/284 32/18639 0.0625 4.1018926056338 0.0851320855979432 0.490260608143768 GO:0071814 protein-lipid complex binding 2/284 32/18639 0.0625 4.1018926056338 0.0851320855979432 0.490260608143768 GO:0005548 phospholipid transporter activity 3/284 68/18639 0.0441176470588235 2.8954536039768 0.0853034800143659 0.490260608143768 GO:0004386 helicase activity 5/284 155/18639 0.032258064516129 2.11710586097229 0.0887482313183522 0.490260608143768 GO:0019956 chemokine binding 2/284 33/18639 0.0606060606060606 3.97759282970551 0.0897452195952946 0.490260608143768 GO:0061630 ubiquitin protein ligase activity 9/284 353/18639 0.0254957507082153 1.67329330088178 0.0920017858445788 0.490260608143768 GO:0003714 transcription corepressor activity 6/284 204/18639 0.0294117647058824 1.9303024026512 0.0925295881585411 0.490260608143768 GO:0008376 acetylgalactosaminyltransferase activity 2/284 34/18639 0.0588235294117647 3.8606048053024 0.0944304105671692 0.490260608143768 GO:0030332 cyclin binding 2/284 34/18639 0.0588235294117647 3.8606048053024 0.0944304105671692 0.490260608143768 GO:0017124 SH3 domain binding 4/284 115/18639 0.0347826086956522 2.28279240661359 0.0990560394295992 0.490260608143768 GO:0035401 histone H3Y41 kinase activity 4/284 115/18639 0.0347826086956522 2.28279240661359 0.0990560394295992 0.490260608143768 GO:0140801 histone H2AXY142 kinase activity 4/284 115/18639 0.0347826086956522 2.28279240661359 0.0990560394295992 0.490260608143768 GO:0008094 ATP-dependent activity, acting on DNA 6/284 210/18639 0.0285714285714286 1.8751509054326 0.102630119394331 0.490260608143768 GO:0003678 DNA helicase activity 3/284 74/18639 0.0405405405405405 2.66068709554625 0.103437465756477 0.490260608143768 GO:0016887 ATP hydrolysis activity 10/284 417/18639 0.0239808153477218 1.57386766643024 0.106345745556522 0.490260608143768 GO:0003725 double-stranded RNA binding 3/284 75/18639 0.04 2.62521126760563 0.106597470718377 0.490260608143768 GO:0019003 GDP binding 3/284 75/18639 0.04 2.62521126760563 0.106597470718377 0.490260608143768 GO:0030551 cyclic nucleotide binding 2/284 37/18639 0.0540540540540541 3.54758279406167 0.108886252757084 0.490260608143768 GO:0005109 frizzled binding 2/284 38/18639 0.0526315789473684 3.45422535211268 0.113828000301003 0.490260608143768 GO:0005201 extracellular matrix structural constituent 5/284 168/18639 0.0297619047619048 1.95328219315895 0.114505844148712 0.490260608143768 GO:0016757 glycosyltransferase activity 7/284 267/18639 0.0262172284644195 1.72064408925463 0.114791201195958 0.490260608143768 GO:0019199 transmembrane receptor protein kinase activity 3/284 78/18639 0.0384615384615385 2.52424160346696 0.116299176441012 0.490260608143768 GO:0030331 nuclear estrogen receptor binding 2/284 40/18639 0.05 3.28151408450704 0.123878488701674 0.490260608143768 GO:0030971 receptor tyrosine kinase binding 3/284 81/18639 0.037037037037037 2.43075117370892 0.12631807669943 0.490260608143768 GO:0001727 lipid kinase activity 2/284 41/18639 0.0487804878048781 3.20147715561663 0.128981589581616 0.490260608143768 GO:0140318 protein transporter activity 2/284 41/18639 0.0487804878048781 3.20147715561663 0.128981589581616 0.490260608143768 GO:0019783 ubiquitin-like protein peptidase activity 4/284 127/18639 0.031496062992126 2.06709548630365 0.129277279123195 0.490260608143768 GO:0042826 histone deacetylase binding 4/284 127/18639 0.031496062992126 2.06709548630365 0.129277279123195 0.490260608143768 GO:0031490 chromatin DNA binding 4/284 128/18639 0.03125 2.0509463028169 0.131952861303694 0.490260608143768 GO:0030165 PDZ domain binding 3/284 83/18639 0.036144578313253 2.37217885627015 0.133163737647694 0.490260608143768 GO:0004520 DNA endonuclease activity 2/284 42/18639 0.0476190476190476 3.12525150905433 0.134132955621509 0.490260608143768 GO:0048487 beta-tubulin binding 2/284 42/18639 0.0476190476190476 3.12525150905433 0.134132955621509 0.490260608143768 GO:0051117 ATPase binding 3/284 84/18639 0.0357142857142857 2.34393863179074 0.136634263444777 0.490260608143768 GO:0005245 voltage-gated calcium channel activity 2/284 43/18639 0.0465116279069767 3.0525712414019 0.139329945562015 0.490260608143768 GO:0000182 rDNA binding 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0005381 iron ion transmembrane transporter activity 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0008140 cAMP response element binding protein binding 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0015203 polyamine transmembrane transporter activity 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0030957 Tat protein binding 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0031419 cobalamin binding 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0035256 G protein-coupled glutamate receptor binding 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0042975 peroxisome proliferator activated receptor binding 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0047429 nucleoside triphosphate diphosphatase activity 1/284 10/18639 0.1 6.56302816901408 0.142366816737972 0.490260608143768 GO:0140097 catalytic activity, acting on DNA 8/284 336/18639 0.0238095238095238 1.56262575452716 0.14268120515381 0.490260608143768 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/284 86/18639 0.0348837209302326 2.28942843105142 0.143666992793874 0.490260608143768 GO:0035091 phosphatidylinositol binding 7/284 284/18639 0.0246478873239437 1.61764778813727 0.144358224837248 0.490260608143768 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/284 44/18639 0.0454545454545455 2.98319462227913 0.144569986907476 0.490260608143768 GO:0004842 ubiquitin-protein transferase activity 10/284 449/18639 0.022271714922049 1.46169892405659 0.149605924584231 0.490260608143768 GO:0046915 transition metal ion transmembrane transporter activity 2/284 45/18639 0.0444444444444444 2.9169014084507 0.149850574456035 0.490260608143768 GO:0051539 4 iron, 4 sulfur cluster binding 2/284 45/18639 0.0444444444444444 2.9169014084507 0.149850574456035 0.490260608143768 GO:0008237 metallopeptidase activity 5/284 184/18639 0.0271739130434783 1.78343156766687 0.150501021996238 0.490260608143768 GO:0004197 cysteine-type endopeptidase activity 3/284 88/18639 0.0340909090909091 2.23739596670935 0.150817009137878 0.490260608143768 GO:0044325 transmembrane transporter binding 4/284 136/18639 0.0294117647058824 1.9303024026512 0.154150488453184 0.490260608143768 GO:0140789 histone phosphatase activity 4/284 136/18639 0.0294117647058824 1.9303024026512 0.154150488453184 0.490260608143768 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/284 89/18639 0.0337078651685393 2.21225668618452 0.154434146209629 0.490260608143768 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/284 89/18639 0.0337078651685393 2.21225668618452 0.154434146209629 0.490260608143768 GO:0004180 carboxypeptidase activity 2/284 46/18639 0.0434782608695652 2.85349050826699 0.155169268858329 0.490260608143768 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0002162 dystroglycan binding 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0003953 NAD+ nucleosidase activity 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0008172 S-methyltransferase activity 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0008432 JUN kinase binding 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0019206 nucleoside kinase activity 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0032794 GTPase activating protein binding 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0043522 leucine zipper domain binding 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0050786 RAGE receptor binding 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0050998 nitric-oxide synthase binding 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/284 11/18639 0.0909090909090909 5.96638924455826 0.155441475820393 0.490260608143768 GO:0140793 histone H2AXY142 phosphatase activity 3/284 90/18639 0.0333333333333333 2.18767605633803 0.158078382952562 0.490260608143768 GO:0001784 phosphotyrosine residue binding 2/284 47/18639 0.0425531914893617 2.79277794426131 0.160523695204228 0.490260608143768 GO:0043495 protein-membrane adaptor activity 2/284 47/18639 0.0425531914893617 2.79277794426131 0.160523695204228 0.490260608143768 GO:0140359 ABC-type transporter activity 2/284 47/18639 0.0425531914893617 2.79277794426131 0.160523695204228 0.490260608143768 GO:0140938 histone H3 methyltransferase activity 2/284 47/18639 0.0425531914893617 2.79277794426131 0.160523695204228 0.490260608143768 GO:1990518 single-stranded 3'-5' DNA helicase activity 2/284 47/18639 0.0425531914893617 2.79277794426131 0.160523695204228 0.490260608143768 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 8/284 349/18639 0.0229226361031519 1.50441906453045 0.165178722424789 0.490260608143768 GO:0043178 alcohol binding 3/284 92/18639 0.0326086956521739 2.14011788120024 0.165445207194669 0.490260608143768 GO:0032266 phosphatidylinositol-3-phosphate binding 2/284 48/18639 0.0416666666666667 2.73459507042254 0.165911541637114 0.490260608143768 GO:0038187 pattern recognition receptor activity 2/284 48/18639 0.0416666666666667 2.73459507042254 0.165911541637114 0.490260608143768 GO:0043138 3'-5' DNA helicase activity 2/284 48/18639 0.0416666666666667 2.73459507042254 0.165911541637114 0.490260608143768 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 6/284 243/18639 0.0246913580246914 1.62050078247261 0.167607081407019 0.490260608143768 GO:0005078 MAP-kinase scaffold activity 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0005095 GTPase inhibitor activity 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0005247 voltage-gated chloride channel activity 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0031543 peptidyl-proline dioxygenase activity 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0035197 siRNA binding 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0035259 nuclear glucocorticoid receptor binding 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0070008 serine-type exopeptidase activity 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0097371 MDM2/MDM4 family protein binding 1/284 12/18639 0.0833333333333333 5.46919014084507 0.168317502278789 0.490260608143768 GO:0005004 GPI-linked ephrin receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0005008 hepatocyte growth factor receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0005009 insulin receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0005011 macrophage colony-stimulating factor receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0005020 stem cell factor receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0008288 boss receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0036332 placental growth factor receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0038062 protein tyrosine kinase collagen receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0060175 brain-derived neurotrophic factor receptor activity 2/284 49/18639 0.0408163265306122 2.67878700776085 0.171330557995185 0.490260608143768 GO:0004676 3-phosphoinositide-dependent protein kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0004711 ribosomal protein S6 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0035175 histone H3S10 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0035979 histone H2AXS139 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0044022 histone H3S28 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0044023 histone H4S1 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0044024 histone H2AS1 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0044025 histone H2BS14 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0072354 histone H3T3 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0072371 histone H2AS121 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0072518 Rho-dependent protein serine/threonine kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0140823 histone H2BS36 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0140855 histone H3S57 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0140995 histone H2A kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0140997 histone H4 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0140998 histone H2B kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:1990244 histone H2AT120 kinase activity 6/284 245/18639 0.0244897959183673 1.60727220465651 0.172011854828844 0.490260608143768 GO:0004677 DNA-dependent protein kinase activity 6/284 246/18639 0.024390243902439 1.60073857780831 0.174232208367202 0.490260608143768 GO:0140857 histone H3T45 kinase activity 6/284 246/18639 0.024390243902439 1.60073857780831 0.174232208367202 0.490260608143768 GO:0035402 histone H3T11 kinase activity 6/284 247/18639 0.0242914979757085 1.59425785482124 0.176464371665266 0.490260608143768 GO:0035403 histone H3T6 kinase activity 6/284 247/18639 0.0242914979757085 1.59425785482124 0.176464371665266 0.490260608143768 GO:0008276 protein methyltransferase activity 3/284 95/18639 0.0315789473684211 2.07253521126761 0.176680325864353 0.490260608143768 GO:0005007 fibroblast growth factor receptor activity 2/284 50/18639 0.04 2.62521126760563 0.176778554479288 0.490260608143768 GO:0005017 platelet-derived growth factor receptor activity 2/284 50/18639 0.04 2.62521126760563 0.176778554479288 0.490260608143768 GO:0005019 platelet-derived growth factor beta-receptor activity 2/284 50/18639 0.04 2.62521126760563 0.176778554479288 0.490260608143768 GO:0004679 AMP-activated protein kinase activity 6/284 248/18639 0.0241935483870968 1.58782939572921 0.178708217192188 0.490260608143768 GO:0008194 UDP-glycosyltransferase activity 4/284 145/18639 0.0275862068965517 1.8104905293832 0.180656862442163 0.490260608143768 GO:0004535 poly(A)-specific ribonuclease activity 1/284 13/18639 0.0769230769230769 5.04848320693391 0.180997903274807 0.490260608143768 GO:0008035 high-density lipoprotein particle binding 1/284 13/18639 0.0769230769230769 5.04848320693391 0.180997903274807 0.490260608143768 GO:0008253 5'-nucleotidase activity 1/284 13/18639 0.0769230769230769 5.04848320693391 0.180997903274807 0.490260608143768 GO:0043560 insulin receptor substrate binding 1/284 13/18639 0.0769230769230769 5.04848320693391 0.180997903274807 0.490260608143768 GO:0046975 histone H3K36 methyltransferase activity 1/284 13/18639 0.0769230769230769 5.04848320693391 0.180997903274807 0.490260608143768 GO:0071837 HMG box domain binding 1/284 13/18639 0.0769230769230769 5.04848320693391 0.180997903274807 0.490260608143768 GO:0140333 glycerophospholipid flippase activity 1/284 13/18639 0.0769230769230769 5.04848320693391 0.180997903274807 0.490260608143768 GO:0005010 insulin-like growth factor receptor activity 2/284 51/18639 0.0392156862745098 2.57373653686827 0.182253400346795 0.490260608143768 GO:0005021 vascular endothelial growth factor receptor activity 2/284 51/18639 0.0392156862745098 2.57373653686827 0.182253400346795 0.490260608143768 GO:0005030 neurotrophin receptor activity 2/284 51/18639 0.0392156862745098 2.57373653686827 0.182253400346795 0.490260608143768 GO:0015085 calcium ion transmembrane transporter activity 4/284 147/18639 0.0272108843537415 1.7858580051739 0.186744145201488 0.490260608143768 GO:0030159 signaling receptor complex adaptor activity 2/284 52/18639 0.0384615384615385 2.52424160346696 0.187753022631043 0.490260608143768 GO:0004725 protein tyrosine phosphatase activity 3/284 98/18639 0.0306122448979592 2.00909025582064 0.188119870406776 0.490260608143768 GO:0042626 ATPase-coupled transmembrane transporter activity 3/284 98/18639 0.0306122448979592 2.00909025582064 0.188119870406776 0.490260608143768 GO:0019209 kinase activator activity 4/284 148/18639 0.027027027027027 1.77379139703083 0.189812572954686 0.490260608143768 GO:0005003 ephrin receptor activity 2/284 53/18639 0.0377358490566038 2.47661440340154 0.19327540488586 0.490260608143768 GO:0005005 transmembrane-ephrin receptor activity 2/284 53/18639 0.0377358490566038 2.47661440340154 0.19327540488586 0.490260608143768 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/284 53/18639 0.0377358490566038 2.47661440340154 0.19327540488586 0.490260608143768 GO:0038064 collagen receptor activity 2/284 53/18639 0.0377358490566038 2.47661440340154 0.19327540488586 0.490260608143768 GO:0140296 general transcription initiation factor binding 2/284 53/18639 0.0377358490566038 2.47661440340154 0.19327540488586 0.490260608143768 GO:0008474 palmitoyl-(protein) hydrolase activity 1/284 14/18639 0.0714285714285714 4.68787726358149 0.193485640602733 0.490260608143768 GO:0008494 translation activator activity 1/284 14/18639 0.0714285714285714 4.68787726358149 0.193485640602733 0.490260608143768 GO:0015926 glucosidase activity 1/284 14/18639 0.0714285714285714 4.68787726358149 0.193485640602733 0.490260608143768 GO:0046030 inositol trisphosphate phosphatase activity 1/284 14/18639 0.0714285714285714 4.68787726358149 0.193485640602733 0.490260608143768 GO:0061665 SUMO ligase activity 1/284 14/18639 0.0714285714285714 4.68787726358149 0.193485640602733 0.490260608143768 GO:0098599 palmitoyl hydrolase activity 1/284 14/18639 0.0714285714285714 4.68787726358149 0.193485640602733 0.490260608143768 GO:1990825 sequence-specific mRNA binding 1/284 14/18639 0.0714285714285714 4.68787726358149 0.193485640602733 0.490260608143768 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/284 54/18639 0.037037037037037 2.43075117370892 0.198818585954722 0.49943738896024 GO:0140463 chromatin-protein adaptor activity 2/284 54/18639 0.037037037037037 2.43075117370892 0.198818585954722 0.49943738896024 GO:0008238 exopeptidase activity 3/284 102/18639 0.0294117647058824 1.9303024026512 0.203657203695202 0.49943738896024 GO:0061775 cohesin loader activity 4/284 153/18639 0.0261437908496732 1.71582435791218 0.205388622813691 0.49943738896024 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 10/284 484/18639 0.0206611570247934 1.35599755558142 0.205601530719319 0.49943738896024 GO:0004559 alpha-mannosidase activity 1/284 15/18639 0.0666666666666667 4.37535211267606 0.205783631371529 0.49943738896024 GO:0005041 low-density lipoprotein particle receptor activity 1/284 15/18639 0.0666666666666667 4.37535211267606 0.205783631371529 0.49943738896024 GO:0008252 nucleotidase activity 1/284 15/18639 0.0666666666666667 4.37535211267606 0.205783631371529 0.49943738896024 GO:0033130 acetylcholine receptor binding 1/284 15/18639 0.0666666666666667 4.37535211267606 0.205783631371529 0.49943738896024 GO:0034483 heparan sulfate sulfotransferase activity 1/284 15/18639 0.0666666666666667 4.37535211267606 0.205783631371529 0.49943738896024 GO:0061578 K63-linked deubiquitinase activity 1/284 15/18639 0.0666666666666667 4.37535211267606 0.205783631371529 0.49943738896024 GO:0051015 actin filament binding 5/284 209/18639 0.0239234449760766 1.57010243277849 0.214676104527993 0.49943738896024 GO:0001216 DNA-binding transcription activator activity 10/284 491/18639 0.0203665987780041 1.33666561487049 0.217758252530758 0.49943738896024 GO:0003688 DNA replication origin binding 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0004708 MAP kinase kinase activity 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0005159 insulin-like growth factor receptor binding 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0008296 3'-5'-DNA exonuclease activity 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0015562 efflux transmembrane transporter activity 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0015923 mannosidase activity 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0030275 LRR domain binding 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0043023 ribosomal large subunit binding 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0140327 flippase activity 1/284 16/18639 0.0625 4.1018926056338 0.217894748676645 0.49943738896024 GO:0008013 beta-catenin binding 3/284 106/18639 0.0283018867924528 1.85746080255116 0.219478729834905 0.49943738896024 GO:0008408 3'-5' exonuclease activity 2/284 58/18639 0.0344827586206897 2.26311316172899 0.221161943465011 0.49943738896024 GO:0017116 single-stranded DNA helicase activity 2/284 58/18639 0.0344827586206897 2.26311316172899 0.221161943465011 0.49943738896024 GO:0001786 phosphatidylserine binding 2/284 59/18639 0.0338983050847458 2.2247553115302 0.226781553243305 0.49943738896024 GO:0045309 protein phosphorylated amino acid binding 2/284 59/18639 0.0338983050847458 2.2247553115302 0.226781553243305 0.49943738896024 GO:0070063 RNA polymerase binding 2/284 59/18639 0.0338983050847458 2.2247553115302 0.226781553243305 0.49943738896024 GO:0005496 steroid binding 3/284 108/18639 0.0277777777777778 1.82306338028169 0.227482391271953 0.49943738896024 GO:0005543 phospholipid binding 10/284 497/18639 0.0201207243460765 1.32052880664267 0.228404151506867 0.49943738896024 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0004659 prenyltransferase activity 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0016805 dipeptidase activity 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0019198 transmembrane receptor protein phosphatase activity 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0030169 low-density lipoprotein particle binding 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0030548 acetylcholine receptor regulator activity 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0032183 SUMO binding 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0038191 neuropilin binding 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0046965 nuclear retinoid X receptor binding 1/284 17/18639 0.0588235294117647 3.8606048053024 0.229821822261773 0.49943738896024 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/284 60/18639 0.0333333333333333 2.18767605633803 0.23241129004193 0.49943738896024 GO:0019905 syntaxin binding 2/284 61/18639 0.0327868852459016 2.15181251443085 0.238049547243442 0.49943738896024 GO:0016791 phosphatase activity 6/284 273/18639 0.021978021978022 1.44242377340969 0.238208386772635 0.49943738896024 GO:1902936 phosphatidylinositol bisphosphate binding 3/284 111/18639 0.027027027027027 1.77379139703083 0.239589033049712 0.49943738896024 GO:0000900 mRNA regulatory element binding translation repressor activity 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0004970 glutamate-gated receptor activity 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0008308 voltage-gated monoatomic anion channel activity 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0008525 phosphatidylcholine transporter activity 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0015280 ligand-gated sodium channel activity 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0017075 syntaxin-1 binding 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0017128 phospholipid scramblase activity 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0030228 lipoprotein particle receptor activity 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0031690 adrenergic receptor binding 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0050811 GABA receptor binding 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0070064 proline-rich region binding 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0070628 proteasome binding 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0099602 neurotransmitter receptor regulator activity 1/284 18/18639 0.0555555555555556 3.64612676056338 0.24156763917068 0.49943738896024 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/284 19/18639 0.0526315789473684 3.45422535211268 0.253134944389279 0.508766448405495 GO:0005229 intracellularly calcium-gated chloride channel activity 1/284 19/18639 0.0526315789473684 3.45422535211268 0.253134944389279 0.508766448405495 GO:0030506 ankyrin binding 1/284 19/18639 0.0526315789473684 3.45422535211268 0.253134944389279 0.508766448405495 GO:0042800 histone H3K4 methyltransferase activity 1/284 19/18639 0.0526315789473684 3.45422535211268 0.253134944389279 0.508766448405495 GO:0043395 heparan sulfate proteoglycan binding 1/284 19/18639 0.0526315789473684 3.45422535211268 0.253134944389279 0.508766448405495 GO:0046624 sphingolipid transporter activity 1/284 19/18639 0.0526315789473684 3.45422535211268 0.253134944389279 0.508766448405495 GO:0050145 nucleoside monophosphate kinase activity 1/284 19/18639 0.0526315789473684 3.45422535211268 0.253134944389279 0.508766448405495 GO:0140036 ubiquitin-modified protein reader activity 1/284 19/18639 0.0526315789473684 3.45422535211268 0.253134944389279 0.508766448405495 GO:0141147 intracellularly calcium-gated channel activity 1/284 19/18639 0.0526315789473684 3.45422535211268 0.253134944389279 0.508766448405495 GO:0004536 DNA nuclease activity 2/284 64/18639 0.03125 2.0509463028169 0.255000063087269 0.508766448405495 GO:0030246 carbohydrate binding 6/284 280/18639 0.0214285714285714 1.40636317907445 0.255868308834144 0.508766448405495 GO:0001221 transcription coregulator binding 3/284 115/18639 0.0260869565217391 1.7120943049602 0.255892916927986 0.508766448405495 GO:0101005 deubiquitinase activity 3/284 115/18639 0.0260869565217391 1.7120943049602 0.255892916927986 0.508766448405495 GO:0019208 phosphatase regulator activity 3/284 117/18639 0.0256410256410256 1.68282773564464 0.264102854444057 0.518287271965769 GO:0030742 GTP-dependent protein binding 1/284 20/18639 0.05 3.28151408450704 0.264526441478078 0.518287271965769 GO:0031418 L-ascorbic acid binding 1/284 20/18639 0.05 3.28151408450704 0.264526441478078 0.518287271965769 GO:0043024 ribosomal small subunit binding 1/284 20/18639 0.05 3.28151408450704 0.264526441478078 0.518287271965769 GO:0052745 inositol phosphate phosphatase activity 1/284 20/18639 0.05 3.28151408450704 0.264526441478078 0.518287271965769 GO:0008235 metalloexopeptidase activity 2/284 66/18639 0.0303030303030303 1.98879641485275 0.266315590002889 0.520280312063615 GO:0005244 voltage-gated monoatomic ion channel activity 4/284 173/18639 0.023121387283237 1.51746316046568 0.270836905630432 0.525626143893192 GO:0042054 histone methyltransferase activity 2/284 67/18639 0.0298507462686567 1.95911288627286 0.27197375126492 0.525626143893192 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/284 21/18639 0.0476190476190476 3.12525150905433 0.275744793195154 0.525626143893192 GO:0001846 opsonin binding 1/284 21/18639 0.0476190476190476 3.12525150905433 0.275744793195154 0.525626143893192 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/284 21/18639 0.0476190476190476 3.12525150905433 0.275744793195154 0.525626143893192 GO:0051010 microtubule plus-end binding 1/284 21/18639 0.0476190476190476 3.12525150905433 0.275744793195154 0.525626143893192 GO:0061891 calcium ion sensor activity 1/284 21/18639 0.0476190476190476 3.12525150905433 0.275744793195154 0.525626143893192 GO:0004721 phosphoprotein phosphatase activity 4/284 175/18639 0.0228571428571429 1.50012072434608 0.277590391436135 0.525626143893192 GO:0022832 voltage-gated channel activity 4/284 175/18639 0.0228571428571429 1.50012072434608 0.277590391436135 0.525626143893192 GO:0030145 manganese ion binding 2/284 68/18639 0.0294117647058824 1.9303024026512 0.2776304261513 0.525626143893192 GO:0140223 general transcription initiation factor activity 2/284 68/18639 0.0294117647058824 1.9303024026512 0.2776304261513 0.525626143893192 GO:0003697 single-stranded DNA binding 3/284 121/18639 0.0247933884297521 1.62719706669771 0.280614482169747 0.529787565777057 GO:0002039 p53 binding 2/284 69/18639 0.0289855072463768 1.90232700551133 0.283284350570289 0.530631382956022 GO:0016279 protein-lysine N-methyltransferase activity 2/284 69/18639 0.0289855072463768 1.90232700551133 0.283284350570289 0.530631382956022 GO:0043021 ribonucleoprotein complex binding 4/284 177/18639 0.0225988700564972 1.4831702076868 0.284371093510047 0.530631382956022 GO:0061133 endopeptidase activator activity 1/284 22/18639 0.0454545454545455 2.98319462227913 0.286792622109783 0.530631382956022 GO:0070034 telomerase RNA binding 1/284 22/18639 0.0454545454545455 2.98319462227913 0.286792622109783 0.530631382956022 GO:0140035 ubiquitin-like protein reader activity 1/284 22/18639 0.0454545454545455 2.98319462227913 0.286792622109783 0.530631382956022 GO:0140784 metal ion sensor activity 1/284 22/18639 0.0454545454545455 2.98319462227913 0.286792622109783 0.530631382956022 GO:0016278 lysine N-methyltransferase activity 2/284 70/18639 0.0285714285714286 1.8751509054326 0.288934299027982 0.530631382956022 GO:0016782 transferase activity, transferring sulphur-containing groups 2/284 70/18639 0.0285714285714286 1.8751509054326 0.288934299027982 0.530631382956022 GO:0097110 scaffold protein binding 2/284 70/18639 0.0285714285714286 1.8751509054326 0.288934299027982 0.530631382956022 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/284 23/18639 0.0434782608695652 2.85349050826699 0.297672511206889 0.535612154157121 GO:0008171 O-methyltransferase activity 1/284 23/18639 0.0434782608695652 2.85349050826699 0.297672511206889 0.535612154157121 GO:0043274 phospholipase binding 1/284 23/18639 0.0434782608695652 2.85349050826699 0.297672511206889 0.535612154157121 GO:0044013 histone H2B acetyltransferase activity 1/284 23/18639 0.0434782608695652 2.85349050826699 0.297672511206889 0.535612154157121 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/284 23/18639 0.0434782608695652 2.85349050826699 0.297672511206889 0.535612154157121 GO:0099186 structural constituent of postsynapse 1/284 23/18639 0.0434782608695652 2.85349050826699 0.297672511206889 0.535612154157121 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/284 23/18639 0.0434782608695652 2.85349050826699 0.297672511206889 0.535612154157121 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/284 181/18639 0.0220994475138122 1.45039296552797 0.298003794968725 0.535612154157121 GO:0005518 collagen binding 2/284 72/18639 0.0277777777777778 1.82306338028169 0.300217553837081 0.538155934271789 GO:0043539 protein serine/threonine kinase activator activity 2/284 73/18639 0.0273972602739726 1.79808990931893 0.305848594397045 0.538478862749092 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/284 24/18639 0.0416666666666667 2.73459507042254 0.308387004482418 0.538478862749092 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/284 24/18639 0.0416666666666667 2.73459507042254 0.308387004482418 0.538478862749092 GO:0004622 lysophospholipase activity 1/284 24/18639 0.0416666666666667 2.73459507042254 0.308387004482418 0.538478862749092 GO:0005315 phosphate transmembrane transporter activity 1/284 24/18639 0.0416666666666667 2.73459507042254 0.308387004482418 0.538478862749092 GO:0030215 semaphorin receptor binding 1/284 24/18639 0.0416666666666667 2.73459507042254 0.308387004482418 0.538478862749092 GO:0048027 mRNA 5'-UTR binding 1/284 24/18639 0.0416666666666667 2.73459507042254 0.308387004482418 0.538478862749092 GO:0050431 transforming growth factor beta binding 1/284 24/18639 0.0416666666666667 2.73459507042254 0.308387004482418 0.538478862749092 GO:0070300 phosphatidic acid binding 1/284 24/18639 0.0416666666666667 2.73459507042254 0.308387004482418 0.538478862749092 GO:0070840 dynein complex binding 1/284 24/18639 0.0416666666666667 2.73459507042254 0.308387004482418 0.538478862749092 GO:0031491 nucleosome binding 2/284 74/18639 0.027027027027027 1.77379139703083 0.311471125748172 0.540068800951994 GO:0048029 monosaccharide binding 2/284 74/18639 0.027027027027027 1.77379139703083 0.311471125748172 0.540068800951994 GO:0042578 phosphoric ester hydrolase activity 7/284 363/18639 0.0192837465564738 1.26559771854266 0.317501653554385 0.540068800951994 GO:0016798 hydrolase activity, acting on glycosyl bonds 3/284 130/18639 0.0230769230769231 1.51454496208017 0.318045515087352 0.540068800951994 GO:0008234 cysteine-type peptidase activity 4/284 187/18639 0.0213903743315508 1.40385629283724 0.318593136854259 0.540068800951994 GO:0000030 mannosyltransferase activity 1/284 25/18639 0.04 2.62521126760563 0.318938607529799 0.540068800951994 GO:0005251 delayed rectifier potassium channel activity 1/284 25/18639 0.04 2.62521126760563 0.318938607529799 0.540068800951994 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/284 25/18639 0.04 2.62521126760563 0.318938607529799 0.540068800951994 GO:0019211 phosphatase activator activity 1/284 25/18639 0.04 2.62521126760563 0.318938607529799 0.540068800951994 GO:0042974 nuclear retinoic acid receptor binding 1/284 25/18639 0.04 2.62521126760563 0.318938607529799 0.540068800951994 GO:0120020 cholesterol transfer activity 1/284 25/18639 0.04 2.62521126760563 0.318938607529799 0.540068800951994 GO:0005262 calcium channel activity 3/284 131/18639 0.0229007633587786 1.5029835501559 0.322215762127452 0.540068800951994 GO:0051536 iron-sulfur cluster binding 2/284 76/18639 0.0263157894736842 1.72711267605634 0.322686513256579 0.540068800951994 GO:0033218 amide binding 5/284 247/18639 0.0202429149797571 1.32854821235103 0.324381242386249 0.540068800951994 GO:0051540 metal cluster binding 2/284 77/18639 0.025974025974026 1.70468264130236 0.328277378858432 0.540068800951994 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0004529 DNA exonuclease activity 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0005112 Notch binding 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0005227 calcium-activated cation channel activity 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0008066 glutamate receptor activity 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0008157 protein phosphatase 1 binding 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0008198 ferrous iron binding 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0030247 polysaccharide binding 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0052742 phosphatidylinositol kinase activity 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0070006 metalloaminopeptidase activity 1/284 26/18639 0.0384615384615385 2.52424160346696 0.329329788117611 0.540068800951994 GO:0005044 scavenger receptor activity 1/284 27/18639 0.037037037037037 2.43075117370892 0.339562976758593 0.550157322921374 GO:0005104 fibroblast growth factor receptor binding 1/284 27/18639 0.037037037037037 2.43075117370892 0.339562976758593 0.550157322921374 GO:0005385 zinc ion transmembrane transporter activity 1/284 27/18639 0.037037037037037 2.43075117370892 0.339562976758593 0.550157322921374 GO:0008320 protein transmembrane transporter activity 1/284 27/18639 0.037037037037037 2.43075117370892 0.339562976758593 0.550157322921374 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/284 27/18639 0.037037037037037 2.43075117370892 0.339562976758593 0.550157322921374 GO:0000049 tRNA binding 2/284 80/18639 0.025 1.64075704225352 0.344971393235683 0.557579661968466 GO:0045499 chemorepellent activity 1/284 28/18639 0.0357142857142857 2.34393863179074 0.349640567270121 0.558430669052278 GO:0046875 ephrin receptor binding 1/284 28/18639 0.0357142857142857 2.34393863179074 0.349640567270121 0.558430669052278 GO:0050698 proteoglycan sulfotransferase activity 1/284 28/18639 0.0357142857142857 2.34393863179074 0.349640567270121 0.558430669052278 GO:0097718 disordered domain specific binding 1/284 28/18639 0.0357142857142857 2.34393863179074 0.349640567270121 0.558430669052278 GO:0141052 histone H3 demethylase activity 1/284 28/18639 0.0357142857142857 2.34393863179074 0.349640567270121 0.558430669052278 GO:0030295 protein kinase activator activity 3/284 139/18639 0.0215827338129496 1.41648089978721 0.355550134049895 0.565190543277427 GO:0140767 enzyme-substrate adaptor activity 3/284 139/18639 0.0215827338129496 1.41648089978721 0.355550134049895 0.565190543277427 GO:0099604 ligand-gated calcium channel activity 1/284 29/18639 0.0344827586206897 2.26311316172899 0.359564917326286 0.5688890945491 GO:0106222 lncRNA binding 1/284 29/18639 0.0344827586206897 2.26311316172899 0.359564917326286 0.5688890945491 GO:0004527 exonuclease activity 2/284 84/18639 0.0238095238095238 1.56262575452716 0.367014501592804 0.573580753979589 GO:0022839 monoatomic ion-gated channel activity 1/284 30/18639 0.0333333333333333 2.18767605633803 0.369338349001694 0.573580753979589 GO:0031210 phosphatidylcholine binding 1/284 30/18639 0.0333333333333333 2.18767605633803 0.369338349001694 0.573580753979589 GO:0031624 ubiquitin conjugating enzyme binding 1/284 30/18639 0.0333333333333333 2.18767605633803 0.369338349001694 0.573580753979589 GO:0032452 histone demethylase activity 1/284 30/18639 0.0333333333333333 2.18767605633803 0.369338349001694 0.573580753979589 GO:0033612 receptor serine/threonine kinase binding 1/284 30/18639 0.0333333333333333 2.18767605633803 0.369338349001694 0.573580753979589 GO:0048019 receptor antagonist activity 1/284 30/18639 0.0333333333333333 2.18767605633803 0.369338349001694 0.573580753979589 GO:0098918 structural constituent of synapse 1/284 30/18639 0.0333333333333333 2.18767605633803 0.369338349001694 0.573580753979589 GO:0022843 voltage-gated monoatomic cation channel activity 3/284 143/18639 0.020979020979021 1.37685905643652 0.372150911612387 0.57662003316494 GO:0019903 protein phosphatase binding 3/284 144/18639 0.0208333333333333 1.36729753521127 0.376289469249953 0.579186309825381 GO:0019955 cytokine binding 3/284 144/18639 0.0208333333333333 1.36729753521127 0.376289469249953 0.579186309825381 GO:0008168 methyltransferase activity 4/284 204/18639 0.0196078431372549 1.28686826843413 0.377317121605474 0.579186309825381 GO:0016878 acid-thiol ligase activity 1/284 31/18639 0.032258064516129 2.11710586097229 0.378963149307111 0.579186309825381 GO:0017147 Wnt-protein binding 1/284 31/18639 0.032258064516129 2.11710586097229 0.378963149307111 0.579186309825381 GO:0140457 protein demethylase activity 1/284 31/18639 0.032258064516129 2.11710586097229 0.378963149307111 0.579186309825381 GO:0022884 macromolecule transmembrane transporter activity 1/284 32/18639 0.03125 2.0509463028169 0.388441570717084 0.587017082204742 GO:0031369 translation initiation factor binding 1/284 32/18639 0.03125 2.0509463028169 0.388441570717084 0.587017082204742 GO:0043425 bHLH transcription factor binding 1/284 32/18639 0.03125 2.0509463028169 0.388441570717084 0.587017082204742 GO:0051059 NF-kappaB binding 1/284 32/18639 0.03125 2.0509463028169 0.388441570717084 0.587017082204742 GO:0120015 sterol transfer activity 1/284 32/18639 0.03125 2.0509463028169 0.388441570717084 0.587017082204742 GO:0003924 GTPase activity 6/284 331/18639 0.0181268882175227 1.18967277988171 0.391750318983145 0.590692874708367 GO:0030296 protein tyrosine kinase activator activity 1/284 33/18639 0.0303030303030303 1.98879641485275 0.39777583168964 0.597106705030774 GO:0140416 transcription regulator inhibitor activity 1/284 33/18639 0.0303030303030303 1.98879641485275 0.39777583168964 0.597106705030774 GO:0019842 vitamin binding 3/284 150/18639 0.02 1.31260563380282 0.400992206845338 0.597595884483893 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/284 91/18639 0.021978021978022 1.44242377340969 0.404860999456701 0.597595884483893 GO:0072341 modified amino acid binding 2/284 91/18639 0.021978021978022 1.44242377340969 0.404860999456701 0.597595884483893 GO:0000510 H3-H4 histone complex chaperone activity 3/284 151/18639 0.0198675496688742 1.30391288126108 0.405084356615859 0.597595884483893 GO:0140584 chromatin extrusion motor activity 3/284 151/18639 0.0198675496688742 1.30391288126108 0.405084356615859 0.597595884483893 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/284 151/18639 0.0198675496688742 1.30391288126108 0.405084356615859 0.597595884483893 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/284 151/18639 0.0198675496688742 1.30391288126108 0.405084356615859 0.597595884483893 GO:0015020 glucuronosyltransferase activity 1/284 34/18639 0.0294117647058824 1.9303024026512 0.4069681171782 0.597595884483893 GO:0016831 carboxy-lyase activity 1/284 34/18639 0.0294117647058824 1.9303024026512 0.4069681171782 0.597595884483893 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/284 34/18639 0.0294117647058824 1.9303024026512 0.4069681171782 0.597595884483893 GO:0015616 DNA translocase activity 3/284 152/18639 0.0197368421052632 1.29533450704225 0.409168402934186 0.597863262979825 GO:0140674 ATP-dependent histone chaperone activity 3/284 152/18639 0.0197368421052632 1.29533450704225 0.409168402934186 0.597863262979825 GO:0052689 carboxylic ester hydrolase activity 2/284 92/18639 0.0217391304347826 1.4267452541335 0.410181350395856 0.597863262979825 GO:0008017 microtubule binding 5/284 276/18639 0.0181159420289855 1.18895437844458 0.41179755572744 0.597863262979825 GO:0016741 transferase activity, transferring one-carbon groups 4/284 215/18639 0.0186046511627907 1.22102849656076 0.415140976271829 0.597863262979825 GO:0051219 phosphoprotein binding 2/284 93/18639 0.021505376344086 1.41140390731486 0.415478383896811 0.597863262979825 GO:0000175 3'-5'-RNA exonuclease activity 1/284 35/18639 0.0285714285714286 1.8751509054326 0.416020579135813 0.597863262979825 GO:0010485 histone H4 acetyltransferase activity 1/284 35/18639 0.0285714285714286 1.8751509054326 0.416020579135813 0.597863262979825 GO:0043015 gamma-tubulin binding 1/284 35/18639 0.0285714285714286 1.8751509054326 0.416020579135813 0.597863262979825 GO:0140566 histone reader activity 1/284 35/18639 0.0285714285714286 1.8751509054326 0.416020579135813 0.597863262979825 GO:0001217 DNA-binding transcription repressor activity 5/284 278/18639 0.0179856115107914 1.18040074982268 0.41780786430853 0.599154256476488 GO:0000993 RNA polymerase II complex binding 1/284 36/18639 0.0277777777777778 1.82306338028169 0.42493533701183 0.604232947565345 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/284 36/18639 0.0277777777777778 1.82306338028169 0.42493533701183 0.604232947565345 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/284 36/18639 0.0277777777777778 1.82306338028169 0.42493533701183 0.604232947565345 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/284 36/18639 0.0277777777777778 1.82306338028169 0.42493533701183 0.604232947565345 GO:0004896 cytokine receptor activity 2/284 96/18639 0.0208333333333333 1.36729753521127 0.431224432852091 0.611884774194336 GO:0140658 ATP-dependent chromatin remodeler activity 3/284 158/18639 0.0189873417721519 1.24614458905331 0.43348354528322 0.612837648500044 GO:0043394 proteoglycan binding 1/284 37/18639 0.027027027027027 1.77379139703083 0.433714478241129 0.612837648500044 GO:0030594 neurotransmitter receptor activity 2/284 97/18639 0.0206185567010309 1.3532016843328 0.436423154056035 0.615374907602024 GO:0003689 DNA clamp loader activity 3/284 160/18639 0.01875 1.23056778169014 0.441508824511438 0.617289191679756 GO:0008170 N-methyltransferase activity 2/284 98/18639 0.0204081632653061 1.33939350388043 0.441596139132061 0.617289191679756 GO:0000146 microfilament motor activity 1/284 38/18639 0.0263157894736842 1.72711267605634 0.442360058725997 0.617289191679756 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/284 38/18639 0.0263157894736842 1.72711267605634 0.442360058725997 0.617289191679756 GO:0043531 ADP binding 1/284 38/18639 0.0263157894736842 1.72711267605634 0.442360058725997 0.617289191679756 GO:0008083 growth factor activity 3/284 162/18639 0.0185185185185185 1.21537558685446 0.449490178951225 0.625286307883694 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/284 39/18639 0.0256410256410256 1.68282773564464 0.450874103310794 0.625286307883694 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/284 39/18639 0.0256410256410256 1.68282773564464 0.450874103310794 0.625286307883694 GO:0140713 histone chaperone activity 3/284 164/18639 0.0182926829268293 1.20055393335623 0.457425342044664 0.626599798810033 GO:0004177 aminopeptidase activity 1/284 40/18639 0.025 1.64075704225352 0.45925860624949 0.626599798810033 GO:0004532 RNA exonuclease activity 1/284 40/18639 0.025 1.64075704225352 0.45925860624949 0.626599798810033 GO:0032451 demethylase activity 1/284 40/18639 0.025 1.64075704225352 0.45925860624949 0.626599798810033 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/284 40/18639 0.025 1.64075704225352 0.45925860624949 0.626599798810033 GO:0050997 quaternary ammonium group binding 1/284 40/18639 0.025 1.64075704225352 0.45925860624949 0.626599798810033 GO:0061791 GTPase motor activity 1/284 40/18639 0.025 1.64075704225352 0.45925860624949 0.626599798810033 GO:1990606 membrane scission GTPase motor activity 1/284 40/18639 0.025 1.64075704225352 0.45925860624949 0.626599798810033 GO:0015399 primary active transmembrane transporter activity 3/284 166/18639 0.0180722891566265 1.18608942813508 0.465312149931311 0.630011124272356 GO:0000287 magnesium ion binding 4/284 230/18639 0.0173913043478261 1.1413962033068 0.465827983661079 0.630011124272356 GO:0004812 aminoacyl-tRNA ligase activity 1/284 41/18639 0.024390243902439 1.60073857780831 0.467515531666187 0.630011124272356 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/284 41/18639 0.024390243902439 1.60073857780831 0.467515531666187 0.630011124272356 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/284 41/18639 0.024390243902439 1.60073857780831 0.467515531666187 0.630011124272356 GO:0042169 SH2 domain binding 1/284 41/18639 0.024390243902439 1.60073857780831 0.467515531666187 0.630011124272356 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/284 167/18639 0.0179640718562874 1.17898709623008 0.469236772084158 0.630011124272356 GO:0016874 ligase activity 3/284 167/18639 0.0179640718562874 1.17898709623008 0.469236772084158 0.630011124272356 GO:0001664 G protein-coupled receptor binding 5/284 297/18639 0.0168350168350168 1.10488689714042 0.474244875552638 0.632319433218719 GO:0004402 histone acetyltransferase activity 1/284 42/18639 0.0238095238095238 1.56262575452716 0.47564681400874 0.632319433218719 GO:0031492 nucleosomal DNA binding 1/284 42/18639 0.0238095238095238 1.56262575452716 0.47564681400874 0.632319433218719 GO:0042056 chemoattractant activity 1/284 42/18639 0.0238095238095238 1.56262575452716 0.47564681400874 0.632319433218719 GO:0043175 RNA polymerase core enzyme binding 1/284 42/18639 0.0238095238095238 1.56262575452716 0.47564681400874 0.632319433218719 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/284 43/18639 0.0232558139534884 1.52628562070095 0.483654358495567 0.639182426717671 GO:0008200 ion channel inhibitor activity 1/284 43/18639 0.0232558139534884 1.52628562070095 0.483654358495567 0.639182426717671 GO:0048156 tau protein binding 1/284 43/18639 0.0232558139534884 1.52628562070095 0.483654358495567 0.639182426717671 GO:0008201 heparin binding 3/284 172/18639 0.0174418604651163 1.14471421552571 0.488662304305057 0.641181503678133 GO:0001046 core promoter sequence-specific DNA binding 1/284 44/18639 0.0227272727272727 1.49159731113956 0.491540041555755 0.641181503678133 GO:0016248 channel inhibitor activity 1/284 44/18639 0.0227272727272727 1.49159731113956 0.491540041555755 0.641181503678133 GO:0016790 thiolester hydrolase activity 1/284 44/18639 0.0227272727272727 1.49159731113956 0.491540041555755 0.641181503678133 GO:0030547 signaling receptor inhibitor activity 1/284 44/18639 0.0227272727272727 1.49159731113956 0.491540041555755 0.641181503678133 GO:0043014 alpha-tubulin binding 1/284 44/18639 0.0227272727272727 1.49159731113956 0.491540041555755 0.641181503678133 GO:0004843 cysteine-type deubiquitinase activity 2/284 108/18639 0.0185185185185185 1.21537558685446 0.491826168251624 0.641181503678133 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/284 45/18639 0.0222222222222222 1.45845070422535 0.499305711262567 0.648273123024555 GO:0141110 transporter inhibitor activity 1/284 45/18639 0.0222222222222222 1.45845070422535 0.499305711262567 0.648273123024555 GO:0003735 structural constituent of ribosome 3/284 175/18639 0.0171428571428571 1.12509054325956 0.500151370879479 0.648273123024555 GO:0004222 metalloendopeptidase activity 2/284 110/18639 0.0181818181818182 1.19327784891165 0.501528114182839 0.648809882839219 GO:0005539 glycosaminoglycan binding 4/284 242/18639 0.0165289256198347 1.08479804446514 0.505227939021947 0.652344120499602 GO:0043022 ribosome binding 2/284 112/18639 0.0178571428571429 1.17196931589537 0.511110433746144 0.657933097413979 GO:0005319 lipid transporter activity 3/284 178/18639 0.0168539325842697 1.10612834309226 0.511508817574073 0.657933097413979 GO:0061733 protein-lysine-acetyltransferase activity 1/284 47/18639 0.0212765957446809 1.39638897213066 0.514484263685574 0.657993156971682 GO:0061749 forked DNA-dependent helicase activity 1/284 47/18639 0.0212765957446809 1.39638897213066 0.514484263685574 0.657993156971682 GO:0099095 ligand-gated monoatomic anion channel activity 1/284 47/18639 0.0212765957446809 1.39638897213066 0.514484263685574 0.657993156971682 GO:0005525 GTP binding 6/284 378/18639 0.0158730158730159 1.04175050301811 0.517217808172937 0.660236368766211 GO:0009378 four-way junction helicase activity 1/284 48/18639 0.0208333333333333 1.36729753521127 0.521900704580222 0.661205027983214 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/284 48/18639 0.0208333333333333 1.36729753521127 0.521900704580222 0.661205027983214 GO:0036121 double-stranded DNA helicase activity 1/284 48/18639 0.0208333333333333 1.36729753521127 0.521900704580222 0.661205027983214 GO:0140693 molecular condensate scaffold activity 1/284 48/18639 0.0208333333333333 1.36729753521127 0.521900704580222 0.661205027983214 GO:0016763 pentosyltransferase activity 1/284 49/18639 0.0204081632653061 1.33939350388043 0.529204249300744 0.667946936383336 GO:0035254 glutamate receptor binding 1/284 49/18639 0.0204081632653061 1.33939350388043 0.529204249300744 0.667946936383336 GO:0046873 metal ion transmembrane transporter activity 7/284 450/18639 0.0155555555555556 1.02091549295775 0.531284553328433 0.669319231669839 GO:0061135 endopeptidase regulator activity 3/284 184/18639 0.016304347826087 1.07005894060012 0.533808739588184 0.67043822313485 GO:0022836 gated channel activity 5/284 318/18639 0.0157232704402516 1.03192266808398 0.534433998738165 0.67043822313485 GO:0015631 tubulin binding 6/284 385/18639 0.0155844155844156 1.02280958478142 0.53515691995037 0.67043822313485 GO:0022853 active monoatomic ion transmembrane transporter activity 2/284 118/18639 0.0169491525423729 1.1123776557651 0.539124094410116 0.674155175570349 GO:0005272 sodium channel activity 1/284 51/18639 0.0196078431372549 1.28686826843413 0.543479474621004 0.677089031228385 GO:0016830 carbon-carbon lyase activity 1/284 51/18639 0.0196078431372549 1.28686826843413 0.543479474621004 0.677089031228385 GO:0140597 protein carrier chaperone 3/284 188/18639 0.0159574468085106 1.04729172909799 0.548353674514506 0.681734892382303 GO:0005080 protein kinase C binding 1/284 52/18639 0.0192307692307692 1.26212080173348 0.550454503091395 0.681734892382303 GO:0019902 phosphatase binding 3/284 190/18639 0.0157894736842105 1.0362676056338 0.555526137687694 0.681734892382303 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/284 122/18639 0.0163934426229508 1.07590625721542 0.557176707393228 0.681734892382303 GO:0005246 calcium channel regulator activity 1/284 53/18639 0.0188679245283019 1.23830720170077 0.55732333190304 0.681734892382303 GO:0005544 calcium-dependent phospholipid binding 1/284 53/18639 0.0188679245283019 1.23830720170077 0.55732333190304 0.681734892382303 GO:0008146 sulfotransferase activity 1/284 53/18639 0.0188679245283019 1.23830720170077 0.55732333190304 0.681734892382303 GO:0034212 protein N-acetyltransferase activity 1/284 53/18639 0.0188679245283019 1.23830720170077 0.55732333190304 0.681734892382303 GO:0051018 protein kinase A binding 1/284 53/18639 0.0188679245283019 1.23830720170077 0.55732333190304 0.681734892382303 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/284 53/18639 0.0188679245283019 1.23830720170077 0.55732333190304 0.681734892382303 GO:0003925 G protein activity 1/284 54/18639 0.0185185185185185 1.21537558685446 0.564087572392631 0.687513605411633 GO:0015485 cholesterol binding 1/284 54/18639 0.0185185185185185 1.21537558685446 0.564087572392631 0.687513605411633 GO:0005267 potassium channel activity 2/284 124/18639 0.0161290322580645 1.05855293048614 0.566013392749368 0.688615571684249 GO:0008374 O-acyltransferase activity 1/284 55/18639 0.0181818181818182 1.19327784891165 0.570748811533901 0.69289183391823 GO:0019001 guanyl nucleotide binding 6/284 400/18639 0.015 0.984454225352113 0.572612390938359 0.69289183391823 GO:0032561 guanyl ribonucleotide binding 6/284 400/18639 0.015 0.984454225352113 0.572612390938359 0.69289183391823 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/284 56/18639 0.0178571428571429 1.17196931589537 0.577308612304691 0.697322589056204 GO:0004519 endonuclease activity 2/284 127/18639 0.015748031496063 1.03354774315182 0.579029756625351 0.698150368453464 GO:0016504 peptidase activator activity 1/284 57/18639 0.0175438596491228 1.15140845070423 0.583768514048514 0.70260710440839 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 4/284 268/18639 0.0149253731343284 0.979556443136431 0.585749542112662 0.703734743999883 GO:0015459 potassium channel regulator activity 1/284 59/18639 0.0169491525423729 1.1123776557651 0.596394661789084 0.711643400622716 GO:0031593 polyubiquitin modification-dependent protein binding 1/284 59/18639 0.0169491525423729 1.1123776557651 0.596394661789084 0.711643400622716 GO:0070888 E-box binding 1/284 59/18639 0.0169491525423729 1.1123776557651 0.596394661789084 0.711643400622716 GO:0005261 monoatomic cation channel activity 5/284 341/18639 0.0146627565982405 0.962320845896493 0.596555669661476 0.711643400622716 GO:0005179 hormone activity 2/284 132/18639 0.0151515151515152 0.994398207426377 0.600084545912814 0.714588310857308 GO:0001098 basal transcription machinery binding 1/284 60/18639 0.0166666666666667 1.09383802816901 0.602563871479714 0.715014171438956 GO:0001099 basal RNA polymerase II transcription machinery binding 1/284 60/18639 0.0166666666666667 1.09383802816901 0.602563871479714 0.715014171438956 GO:1901681 sulfur compound binding 4/284 275/18639 0.0145454545454545 0.954622279129321 0.606100041571624 0.717946270684138 GO:0051087 protein-folding chaperone binding 2/284 134/18639 0.0149253731343284 0.979556443136431 0.608282393775887 0.718428651989926 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/284 61/18639 0.0163934426229508 1.07590625721542 0.608639110216985 0.718428651989926 GO:0002020 protease binding 2/284 136/18639 0.0147058823529412 0.965151201325601 0.616352291310605 0.723574401194067 GO:0016779 nucleotidyltransferase activity 2/284 136/18639 0.0147058823529412 0.965151201325601 0.616352291310605 0.723574401194067 GO:0099094 ligand-gated monoatomic cation channel activity 2/284 136/18639 0.0147058823529412 0.965151201325601 0.616352291310605 0.723574401194067 GO:0004518 nuclease activity 3/284 209/18639 0.0143540669856459 0.942061459667094 0.620156745604305 0.723574401194067 GO:0016922 nuclear receptor binding 2/284 137/18639 0.0145985401459854 0.958106302045852 0.620339321398835 0.723574401194067 GO:0022824 transmitter-gated monoatomic ion channel activity 1/284 63/18639 0.0158730158730159 1.04175050301811 0.620513358887494 0.723574401194067 GO:0022835 transmitter-gated channel activity 1/284 63/18639 0.0158730158730159 1.04175050301811 0.620513358887494 0.723574401194067 GO:0140101 catalytic activity, acting on a tRNA 2/284 139/18639 0.0143884892086331 0.944320599858142 0.628217727076033 0.731293174523742 GO:0019843 rRNA binding 1/284 65/18639 0.0153846153846154 1.00969664138678 0.632028562097361 0.733196645186955 GO:0120013 lipid transfer activity 1/284 65/18639 0.0153846153846154 1.00969664138678 0.632028562097361 0.733196645186955 GO:0019207 kinase regulator activity 4/284 287/18639 0.0139372822299652 0.914707758747608 0.639542008861373 0.740637996516436 GO:0032934 sterol binding 1/284 68/18639 0.0147058823529412 0.965151201325601 0.648651734932313 0.749899261311114 GO:0008080 N-acetyltransferase activity 1/284 69/18639 0.0144927536231884 0.951163502755664 0.654024784702343 0.753525991263896 GO:0098960 postsynaptic neurotransmitter receptor activity 1/284 69/18639 0.0144927536231884 0.951163502755664 0.654024784702343 0.753525991263896 GO:0140299 molecular sensor activity 1/284 71/18639 0.0140845070422535 0.924370164649871 0.664526477838659 0.764318849937297 GO:0061134 peptidase regulator activity 3/284 226/18639 0.0132743362831858 0.871198429515144 0.672342100142824 0.771990758937416 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/284 73/18639 0.0136986301369863 0.899044954659464 0.674710492153305 0.773392638964842 GO:0031625 ubiquitin protein ligase binding 4/284 302/18639 0.0132450331125828 0.869275254174051 0.678673108925285 0.775312141613886 GO:0003684 damaged DNA binding 1/284 74/18639 0.0135135135135135 0.886895698515417 0.679686373884882 0.775312141613886 GO:0003774 cytoskeletal motor activity 2/284 153/18639 0.0130718954248366 0.85791217895609 0.679836017349862 0.775312141613886 GO:0005506 iron ion binding 2/284 154/18639 0.012987012987013 0.85234132065118 0.683290296484624 0.7779352362004 GO:0017022 myosin binding 1/284 76/18639 0.0131578947368421 0.863556338028169 0.689411736462228 0.781735313353852 GO:0098631 cell adhesion mediator activity 1/284 76/18639 0.0131578947368421 0.863556338028169 0.689411736462228 0.781735313353852 GO:0140375 immune receptor activity 2/284 156/18639 0.0128205128205128 0.841413867822319 0.690107583747095 0.781735313353852 GO:0003724 RNA helicase activity 1/284 77/18639 0.012987012987013 0.85234132065118 0.694163504325436 0.784634055407444 GO:0015079 potassium ion transmembrane transporter activity 2/284 160/18639 0.0125 0.820378521126761 0.703380624972429 0.784634055407444 GO:0099106 ion channel regulator activity 2/284 160/18639 0.0125 0.820378521126761 0.703380624972429 0.784634055407444 GO:0008186 ATP-dependent activity, acting on RNA 1/284 79/18639 0.0126582278481013 0.830763059368872 0.70345080150391 0.784634055407444 GO:0046332 SMAD binding 1/284 79/18639 0.0126582278481013 0.830763059368872 0.70345080150391 0.784634055407444 GO:0140098 catalytic activity, acting on RNA 5/284 387/18639 0.0129198966408269 0.847936455944972 0.705639047038789 0.784634055407444 GO:0004866 endopeptidase inhibitor activity 2/284 161/18639 0.0124223602484472 0.815283002361998 0.706624341809586 0.784634055407444 GO:0048306 calcium-dependent protein binding 1/284 80/18639 0.0125 0.820378521126761 0.707988515532621 0.784634055407444 GO:0015101 organic cation transmembrane transporter activity 1/284 81/18639 0.0123456790123457 0.810250391236307 0.712457035473822 0.784634055407444 GO:0033192 calmodulin-dependent protein phosphatase activity 1/284 81/18639 0.0123456790123457 0.810250391236307 0.712457035473822 0.784634055407444 GO:0140791 histone H2AXS140 phosphatase activity 1/284 81/18639 0.0123456790123457 0.810250391236307 0.712457035473822 0.784634055407444 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/284 81/18639 0.0123456790123457 0.810250391236307 0.712457035473822 0.784634055407444 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/284 81/18639 0.0123456790123457 0.810250391236307 0.712457035473822 0.784634055407444 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/284 81/18639 0.0123456790123457 0.810250391236307 0.712457035473822 0.784634055407444 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/284 81/18639 0.0123456790123457 0.810250391236307 0.712457035473822 0.784634055407444 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/284 81/18639 0.0123456790123457 0.810250391236307 0.712457035473822 0.784634055407444 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/284 81/18639 0.0123456790123457 0.810250391236307 0.712457035473822 0.784634055407444 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/284 82/18639 0.0121951219512195 0.800369288904157 0.716857412773392 0.785270630552691 GO:0033549 MAP kinase phosphatase activity 1/284 82/18639 0.0121951219512195 0.800369288904157 0.716857412773392 0.785270630552691 GO:0015103 inorganic anion transmembrane transporter activity 2/284 165/18639 0.0121212121212121 0.795518565941101 0.71930525821225 0.785270630552691 GO:0001540 amyloid-beta binding 1/284 83/18639 0.0120481927710843 0.790726285423384 0.721190682955661 0.785270630552691 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/284 83/18639 0.0120481927710843 0.790726285423384 0.721190682955661 0.785270630552691 GO:0005254 chloride channel activity 1/284 83/18639 0.0120481927710843 0.790726285423384 0.721190682955661 0.785270630552691 GO:0008135 translation factor activity, RNA binding 1/284 83/18639 0.0120481927710843 0.790726285423384 0.721190682955661 0.785270630552691 GO:0017018 myosin phosphatase activity 1/284 84/18639 0.0119047619047619 0.781312877263581 0.725457865863647 0.786815659607748 GO:0180051 translation factor activity 1/284 84/18639 0.0119047619047619 0.781312877263581 0.725457865863647 0.786815659607748 GO:0044389 ubiquitin-like protein ligase binding 4/284 322/18639 0.0124223602484472 0.815283002361998 0.726111780824954 0.786815659607748 GO:0016247 channel regulator activity 2/284 168/18639 0.0119047619047619 0.781312877263581 0.728511448108141 0.788148821869802 GO:0030414 peptidase inhibitor activity 2/284 169/18639 0.0118343195266272 0.776689724143679 0.73152299587084 0.790138620539978 GO:0140104 molecular carrier activity 3/284 249/18639 0.0120481927710843 0.790726285423384 0.734304171811688 0.790826180908926 GO:0141108 transporter regulator activity 2/284 170/18639 0.0117647058823529 0.772120961060481 0.734506215502949 0.790826180908926 GO:0008081 phosphoric diester hydrolase activity 1/284 87/18639 0.0114942528735632 0.754371053909665 0.737872859096989 0.793183902761356 GO:0004175 endopeptidase activity 5/284 405/18639 0.0123456790123457 0.810250391236307 0.742276383168142 0.796646946266446 GO:0019887 protein kinase regulator activity 3/284 255/18639 0.0117647058823529 0.772120961060481 0.748865400935359 0.802440827075408 GO:0016410 N-acyltransferase activity 1/284 94/18639 0.0106382978723404 0.698194486065328 0.764708511426374 0.81811672492282 GO:0004867 serine-type endopeptidase inhibitor activity 1/284 95/18639 0.0105263157894737 0.690845070422535 0.768311789008197 0.820669010763114 GO:0016407 acetyltransferase activity 1/284 96/18639 0.0104166666666667 0.683648767605634 0.771860076967735 0.823154575753566 GO:0015276 ligand-gated monoatomic ion channel activity 2/284 186/18639 0.010752688172043 0.705701953657428 0.77852056195006 0.827930348720276 GO:0005249 voltage-gated potassium channel activity 1/284 98/18639 0.0102040816326531 0.669696751940213 0.778795016452011 0.827930348720276 GO:0031406 carboxylic acid binding 2/284 187/18639 0.0106951871657754 0.701928146418619 0.781047895163362 0.82901776588993 GO:0022834 ligand-gated channel activity 2/284 188/18639 0.0106382978723404 0.698194486065328 0.783549983557436 0.830365863078163 GO:0043177 organic acid binding 2/284 189/18639 0.0105820105820106 0.694500335345406 0.786027006375207 0.831683206117566 GO:0015171 amino acid transmembrane transporter activity 1/284 102/18639 0.00980392156862745 0.643434134217067 0.792040977622475 0.836166983998189 GO:0005126 cytokine receptor binding 3/284 275/18639 0.0109090909090909 0.715966709346991 0.792837054866715 0.836166983998189 GO:0004722 protein serine/threonine phosphatase activity 1/284 103/18639 0.00970873786407767 0.637187200875154 0.795227057481957 0.836166983998189 GO:0005253 monoatomic anion channel activity 1/284 103/18639 0.00970873786407767 0.637187200875154 0.795227057481957 0.836166983998189 GO:0008236 serine-type peptidase activity 2/284 194/18639 0.0103092783505155 0.6766008421664 0.798042436494022 0.837820252643257 GO:0017171 serine hydrolase activity 2/284 198/18639 0.0101010101010101 0.662932138284251 0.807222000637674 0.845108384544876 GO:0019888 protein phosphatase regulator activity 1/284 107/18639 0.00934579439252336 0.613367118599447 0.807492284342582 0.845108384544876 GO:0004620 phospholipase activity 1/284 109/18639 0.00917431192660551 0.602112676056338 0.813347531742473 0.849916645572754 GO:0005216 monoatomic ion channel activity 5/284 448/18639 0.0111607142857143 0.732480822434608 0.816026071305359 0.85139562238361 GO:0022804 active transmembrane transporter activity 5/284 457/18639 0.0109409190371991 0.718055598360403 0.829116653044681 0.863716575196468 GO:0009055 electron transfer activity 1/284 116/18639 0.00862068965517241 0.565778290432249 0.832478006244251 0.865879901556521 GO:0004540 RNA nuclease activity 1/284 121/18639 0.00826446280991736 0.542399022232569 0.844933971247453 0.874785709094905 GO:0015108 chloride transmembrane transporter activity 1/284 121/18639 0.00826446280991736 0.542399022232569 0.844933971247453 0.874785709094905 GO:0051082 unfolded protein binding 1/284 121/18639 0.00826446280991736 0.542399022232569 0.844933971247453 0.874785709094905 GO:0008528 G protein-coupled peptide receptor activity 1/284 122/18639 0.00819672131147541 0.537953128607712 0.84731213045286 0.875902417063232 GO:0001653 peptide receptor activity 1/284 128/18639 0.0078125 0.512736575704225 0.860836902432786 0.887162189968957 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/284 128/18639 0.0078125 0.512736575704225 0.860836902432786 0.887162189968957 GO:0016298 lipase activity 1/284 130/18639 0.00769230769230769 0.504848320693391 0.865074403452162 0.889582220272055 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/284 229/18639 0.00873362445414847 0.573190233101667 0.866619588207895 0.889582220272055 GO:0031072 heat shock protein binding 1/284 131/18639 0.00763358778625954 0.500994516718632 0.86714468652632 0.889582220272055 GO:0015293 symporter activity 1/284 146/18639 0.00684931506849315 0.449522477329732 0.894657468532974 0.915896948392603 GO:0042277 peptide binding 2/284 249/18639 0.00803212851405622 0.527150856948922 0.895513485149444 0.915896948392603 GO:0008509 monoatomic anion transmembrane transporter activity 1/284 149/18639 0.00671140939597315 0.440471689195576 0.899436858834625 0.918515822506875 GO:0046906 tetrapyrrole binding 1/284 152/18639 0.00657894736842105 0.431778169014085 0.904000137097509 0.921779262335432 GO:0015081 sodium ion transmembrane transporter activity 1/284 164/18639 0.00609756097560976 0.400184644452078 0.920280466794843 0.936962287945203 GO:0140030 modification-dependent protein binding 1/284 173/18639 0.00578034682080925 0.379365790116421 0.930657312065824 0.946098081949269 GO:0004252 serine-type endopeptidase activity 1/284 176/18639 0.00568181818181818 0.372899327784891 0.933807918746225 0.94771751209424 GO:0015291 secondary active transmembrane transporter activity 2/284 287/18639 0.00696864111498258 0.457353879373804 0.935062530478739 0.94771751209424 GO:0016853 isomerase activity 1/284 180/18639 0.00555555555555556 0.364612676056338 0.937787921498345 0.949052641276103 GO:0046943 carboxylic acid transmembrane transporter activity 1/284 188/18639 0.00531914893617021 0.349097243032664 0.945046619637668 0.954388508781907 GO:0005342 organic acid transmembrane transporter activity 1/284 189/18639 0.00529100529100529 0.347250167672703 0.945892468644383 0.954388508781907 GO:0016829 lyase activity 1/284 200/18639 0.005 0.328151408450704 0.954382676012362 0.960102303167477 GO:0004857 enzyme inhibitor activity 3/284 416/18639 0.00721153846153846 0.473295300650054 0.954404366650163 0.960102303167477 GO:0045182 translation regulator activity 2/284 356/18639 0.00561797752808989 0.36870944769742 0.973472858373457 0.977825196041296 GO:0042393 histone binding 1/284 247/18639 0.00404858299595142 0.265709642470206 0.978026531121843 0.980937324369229 GO:0008514 organic anion transmembrane transporter activity 1/284 269/18639 0.00371747211895911 0.243978742342531 0.984399927632588 0.985862631834122 GO:0030371 translation repressor activity 1/284 329/18639 0.00303951367781155 0.199484138875808 0.993883960207137 0.993883960207137