ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005161 platelet-derived growth factor receptor binding 2/55 14/18639 0.142857142857143 48.412987012987 0.000760495972638638 0.114988004844038 GO:0140375 immune receptor activity 4/55 156/18639 0.0256410256410256 8.68951048951049 0.00115557473440066 0.114988004844038 GO:0030506 ankyrin binding 2/55 19/18639 0.105263157894737 35.6727272727273 0.00141560581629595 0.114988004844038 GO:0030247 polysaccharide binding 2/55 26/18639 0.0769230769230769 26.0685314685315 0.00265511588523358 0.114988004844038 GO:0023026 MHC class II protein complex binding 2/55 27/18639 0.0740740740740741 25.1030303030303 0.00286211463206581 0.114988004844038 GO:0003714 transcription corepressor activity 4/55 204/18639 0.0196078431372549 6.64491978609626 0.00307277508122323 0.114988004844038 GO:0141003 histone H2AX kinase activity 5/55 354/18639 0.0141242937853107 4.78659476117103 0.00383972027865535 0.114988004844038 GO:0140996 histone H3 kinase activity 5/55 357/18639 0.0140056022408964 4.74637127578304 0.00397958562187228 0.114988004844038 GO:0035173 histone kinase activity 5/55 360/18639 0.0138888888888889 4.70681818181818 0.00412307587090176 0.114988004844038 GO:0023023 MHC protein complex binding 2/55 37/18639 0.0540540540540541 18.3184275184275 0.0053291889720047 0.11682494648966 GO:0042826 histone deacetylase binding 3/55 127/18639 0.0236220472440945 8.00529706513958 0.00626109081168078 0.11682494648966 GO:0042169 SH2 domain binding 2/55 41/18639 0.0487804878048781 16.5312638580931 0.00651220690212427 0.11682494648966 GO:0140828 metal cation:monoatomic cation antiporter activity 2/55 41/18639 0.0487804878048781 16.5312638580931 0.00651220690212427 0.11682494648966 GO:0044325 transmembrane transporter binding 3/55 136/18639 0.0220588235294118 7.47553475935829 0.00755897212490999 0.11682494648966 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/55 45/18639 0.0444444444444444 15.0618181818182 0.00780332415630438 0.11682494648966 GO:0070851 growth factor receptor binding 3/55 139/18639 0.0215827338129496 7.31419228253761 0.0080243160269271 0.11682494648966 GO:0032266 phosphatidylinositol-3-phosphate binding 2/55 48/18639 0.0416666666666667 14.1204545454545 0.0088410306449822 0.11682494648966 GO:0019207 kinase regulator activity 4/55 287/18639 0.0139372822299652 4.72321824516947 0.0101460255460714 0.11682494648966 GO:0140297 DNA-binding transcription factor binding 5/55 488/18639 0.0102459016393443 3.47224292101341 0.0143210244467096 0.11682494648966 GO:0030695 GTPase regulator activity 5/55 489/18639 0.0102249488752556 3.46514221974345 0.0144370638701871 0.11682494648966 GO:0060589 nucleoside-triphosphatase regulator activity 5/55 490/18639 0.0102040816326531 3.45807050092764 0.0145537380155687 0.11682494648966 GO:0097110 scaffold protein binding 2/55 70/18639 0.0285714285714286 9.6825974025974 0.0181629219427442 0.11682494648966 GO:0046332 SMAD binding 2/55 79/18639 0.0253164556962025 8.5795166858458 0.022785096886205 0.11682494648966 GO:0030165 PDZ domain binding 2/55 83/18639 0.0240963855421687 8.16604600219058 0.0249791092235086 0.11682494648966 GO:0004860 protein kinase inhibitor activity 2/55 84/18639 0.0238095238095238 8.06883116883117 0.0255406392488566 0.11682494648966 GO:0015631 tubulin binding 4/55 385/18639 0.0103896103896104 3.52094451003542 0.0267563550232572 0.11682494648966 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/55 89/18639 0.0224719101123595 7.61552604698672 0.0284247430797533 0.11682494648966 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/55 89/18639 0.0224719101123595 7.61552604698672 0.0284247430797533 0.11682494648966 GO:0019210 kinase inhibitor activity 2/55 90/18639 0.0222222222222222 7.53090909090909 0.0290166183561813 0.11682494648966 GO:0140793 histone H2AXY142 phosphatase activity 2/55 90/18639 0.0222222222222222 7.53090909090909 0.0290166183561813 0.11682494648966 GO:0005131 growth hormone receptor binding 1/55 10/18639 0.1 33.8890909090909 0.0291262021263182 0.11682494648966 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/55 10/18639 0.1 33.8890909090909 0.0291262021263182 0.11682494648966 GO:0032395 MHC class II receptor activity 1/55 10/18639 0.1 33.8890909090909 0.0291262021263182 0.11682494648966 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/55 10/18639 0.1 33.8890909090909 0.0291262021263182 0.11682494648966 GO:0043208 glycosphingolipid binding 1/55 10/18639 0.1 33.8890909090909 0.0291262021263182 0.11682494648966 GO:0070097 delta-catenin binding 1/55 10/18639 0.1 33.8890909090909 0.0291262021263182 0.11682494648966 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/55 10/18639 0.1 33.8890909090909 0.0291262021263182 0.11682494648966 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/55 10/18639 0.1 33.8890909090909 0.0291262021263182 0.11682494648966 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/55 10/18639 0.1 33.8890909090909 0.0291262021263182 0.11682494648966 GO:0019864 IgG binding 1/55 11/18639 0.0909090909090909 30.8082644628099 0.0319925963977795 0.11682494648966 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/55 11/18639 0.0909090909090909 30.8082644628099 0.0319925963977795 0.11682494648966 GO:0032794 GTPase activating protein binding 1/55 11/18639 0.0909090909090909 30.8082644628099 0.0319925963977795 0.11682494648966 GO:0042608 T cell receptor binding 1/55 11/18639 0.0909090909090909 30.8082644628099 0.0319925963977795 0.11682494648966 GO:0050998 nitric-oxide synthase binding 1/55 11/18639 0.0909090909090909 30.8082644628099 0.0319925963977795 0.11682494648966 GO:0140031 phosphorylation-dependent protein binding 1/55 11/18639 0.0909090909090909 30.8082644628099 0.0319925963977795 0.11682494648966 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/55 11/18639 0.0909090909090909 30.8082644628099 0.0319925963977795 0.11682494648966 GO:0004896 cytokine receptor activity 2/55 96/18639 0.0208333333333333 7.06022727272727 0.0326704571634911 0.11682494648966 GO:0004725 protein tyrosine phosphatase activity 2/55 98/18639 0.0204081632653061 6.91614100185529 0.0339266981190084 0.11682494648966 GO:0015368 calcium:monoatomic cation antiporter activity 1/55 12/18639 0.0833333333333333 28.2409090909091 0.0348506813880156 0.11682494648966 GO:0017166 vinculin binding 1/55 12/18639 0.0833333333333333 28.2409090909091 0.0348506813880156 0.11682494648966 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/55 12/18639 0.0833333333333333 28.2409090909091 0.0348506813880156 0.11682494648966 GO:0035259 nuclear glucocorticoid receptor binding 1/55 12/18639 0.0833333333333333 28.2409090909091 0.0348506813880156 0.11682494648966 GO:0035497 cAMP response element binding 1/55 12/18639 0.0833333333333333 28.2409090909091 0.0348506813880156 0.11682494648966 GO:0045295 gamma-catenin binding 1/55 12/18639 0.0833333333333333 28.2409090909091 0.0348506813880156 0.11682494648966 GO:0070679 inositol 1,4,5 trisphosphate binding 1/55 12/18639 0.0833333333333333 28.2409090909091 0.0348506813880156 0.11682494648966 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/55 12/18639 0.0833333333333333 28.2409090909091 0.0348506813880156 0.11682494648966 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/55 243/18639 0.0123456790123457 4.18383838383838 0.0349535410845037 0.11682494648966 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0004711 ribosomal protein S6 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0035175 histone H3S10 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0035979 histone H2AXS139 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0044022 histone H3S28 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0044023 histone H4S1 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0044024 histone H2AS1 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0044025 histone H2BS14 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0072354 histone H3T3 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0072371 histone H2AS121 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0140823 histone H2BS36 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0140855 histone H3S57 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0140995 histone H2A kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0140997 histone H4 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0140998 histone H2B kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:1990244 histone H2AT120 kinase activity 3/55 245/18639 0.0122448979591837 4.14968460111317 0.0356814436283345 0.11682494648966 GO:0004677 DNA-dependent protein kinase activity 3/55 246/18639 0.0121951219512195 4.13281596452328 0.0360483409095259 0.11682494648966 GO:0140857 histone H3T45 kinase activity 3/55 246/18639 0.0121951219512195 4.13281596452328 0.0360483409095259 0.11682494648966 GO:0035402 histone H3T11 kinase activity 3/55 247/18639 0.0121457489878543 4.11608391608392 0.0364171997649631 0.11682494648966 GO:0035403 histone H3T6 kinase activity 3/55 247/18639 0.0121457489878543 4.11608391608392 0.0364171997649631 0.11682494648966 GO:0004679 AMP-activated protein kinase activity 3/55 248/18639 0.0120967741935484 4.09948680351906 0.0367880183191599 0.11682494648966 GO:0043560 insulin receptor substrate binding 1/55 13/18639 0.0769230769230769 26.0685314685315 0.0377004807396911 0.11682494648966 GO:0071837 HMG box domain binding 1/55 13/18639 0.0769230769230769 26.0685314685315 0.0377004807396911 0.11682494648966 GO:0019887 protein kinase regulator activity 3/55 255/18639 0.0117647058823529 3.98695187165775 0.0394384537367464 0.120720144974675 GO:0015386 potassium:proton antiporter activity 1/55 14/18639 0.0714285714285714 24.2064935064935 0.0405420180294644 0.121143411016614 GO:0019763 immunoglobulin receptor activity 1/55 14/18639 0.0714285714285714 24.2064935064935 0.0405420180294644 0.121143411016614 GO:0033130 acetylcholine receptor binding 1/55 15/18639 0.0666666666666667 22.5927272727273 0.0433753167681693 0.124242510945742 GO:0141050 histone H3K deacetylase activity 1/55 15/18639 0.0666666666666667 22.5927272727273 0.0433753167681693 0.124242510945742 GO:0141051 histone H4K deacetylase activity 1/55 15/18639 0.0666666666666667 22.5927272727273 0.0433753167681693 0.124242510945742 GO:0046873 metal ion transmembrane transporter activity 4/55 450/18639 0.00888888888888889 3.01236363636364 0.0435591273435272 0.124242510945742 GO:0035401 histone H3Y41 kinase activity 2/55 115/18639 0.0173913043478261 5.89375494071146 0.045334985649383 0.12604674457228 GO:0140801 histone H2AXY142 kinase activity 2/55 115/18639 0.0173913043478261 5.89375494071146 0.045334985649383 0.12604674457228 GO:0005096 GTPase activator activity 3/55 271/18639 0.011070110701107 3.75155987923516 0.0458528200184706 0.12604674457228 GO:0015385 sodium:proton antiporter activity 1/55 16/18639 0.0625 21.1806818181818 0.0462004004009952 0.12604674457228 GO:0005126 cytokine receptor binding 3/55 275/18639 0.0109090909090909 3.69699173553719 0.0475329611295464 0.126838560507467 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/55 17/18639 0.0588235294117647 19.9347593582888 0.0490172923076667 0.126838560507467 GO:0015278 intracellularly gated calcium channel activity 1/55 17/18639 0.0588235294117647 19.9347593582888 0.0490172923076667 0.126838560507467 GO:0019198 transmembrane receptor protein phosphatase activity 1/55 17/18639 0.0588235294117647 19.9347593582888 0.0490172923076667 0.126838560507467 GO:0046965 nuclear retinoid X receptor binding 1/55 17/18639 0.0588235294117647 19.9347593582888 0.0490172923076667 0.126838560507467 GO:0030246 carbohydrate binding 3/55 280/18639 0.0107142857142857 3.63097402597403 0.0496756802535989 0.127230568812789 GO:0031267 small GTPase binding 3/55 283/18639 0.0106007067137809 3.59248313523932 0.0509838580291874 0.128795346202559 GO:0035091 phosphatidylinositol binding 3/55 284/18639 0.0105633802816901 3.57983354673495 0.0514236565067206 0.128795346202559 GO:0017128 phospholipid scramblase activity 1/55 18/18639 0.0555555555555556 18.8272727272727 0.0518260158026234 0.128795346202559 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/55 19/18639 0.0526315789473684 17.8363636363636 0.054626594135197 0.131839183922447 GO:0022821 solute:potassium antiporter activity 1/55 19/18639 0.0526315789473684 17.8363636363636 0.054626594135197 0.131839183922447 GO:0043395 heparan sulfate proteoglycan binding 1/55 19/18639 0.0526315789473684 17.8363636363636 0.054626594135197 0.131839183922447 GO:0001664 G protein-coupled receptor binding 3/55 297/18639 0.0101010101010101 3.42314049586777 0.0573094978252895 0.136996990039502 GO:0003712 transcription coregulator activity 4/55 495/18639 0.00808080808080808 2.73851239669421 0.058021078889079 0.137389535859989 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/55 21/18639 0.0476190476190476 16.1376623376623 0.0602034079860629 0.137556824486419 GO:0010314 phosphatidylinositol-5-phosphate binding 1/55 21/18639 0.0476190476190476 16.1376623376623 0.0602034079860629 0.137556824486419 GO:0051428 peptide hormone receptor binding 1/55 21/18639 0.0476190476190476 16.1376623376623 0.0602034079860629 0.137556824486419 GO:0015297 antiporter activity 2/55 135/18639 0.0148148148148148 5.02060606060606 0.0602838673048053 0.137556824486419 GO:0140789 histone phosphatase activity 2/55 136/18639 0.0147058823529412 4.98368983957219 0.0610708060388336 0.138097047889615 GO:0004407 histone deacetylase activity 1/55 22/18639 0.0454545454545455 15.404132231405 0.0629796896790895 0.138665807977644 GO:0031683 G-protein beta/gamma-subunit complex binding 1/55 22/18639 0.0454545454545455 15.404132231405 0.0629796896790895 0.138665807977644 GO:0033558 protein lysine deacetylase activity 1/55 22/18639 0.0454545454545455 15.404132231405 0.0629796896790895 0.138665807977644 GO:0004713 protein tyrosine kinase activity 2/55 140/18639 0.0142857142857143 4.8412987012987 0.0642538756488129 0.140241067720452 GO:0042171 lysophosphatidic acid acyltransferase activity 1/55 23/18639 0.0434782608695652 14.7343873517787 0.0657479185595558 0.140315906501769 GO:0071617 lysophospholipid acyltransferase activity 1/55 23/18639 0.0434782608695652 14.7343873517787 0.0657479185595558 0.140315906501769 GO:0051020 GTPase binding 3/55 315/18639 0.00952380952380952 3.22753246753247 0.0659652468813095 0.140315906501769 GO:0004622 lysophospholipase activity 1/55 24/18639 0.0416666666666667 14.1204545454545 0.0685081175539277 0.143296145883632 GO:0035035 histone acetyltransferase binding 1/55 24/18639 0.0416666666666667 14.1204545454545 0.0685081175539277 0.143296145883632 GO:0015085 calcium ion transmembrane transporter activity 2/55 147/18639 0.0136054421768707 4.61076066790352 0.0699561127550434 0.145115572739801 GO:0042974 nuclear retinoic acid receptor binding 1/55 25/18639 0.04 13.5556363636364 0.0712603095246256 0.146609325333451 GO:0019865 immunoglobulin binding 1/55 26/18639 0.0384615384615385 13.0342657342657 0.074004517270201 0.14742169710175 GO:0030507 spectrin binding 1/55 26/18639 0.0384615384615385 13.0342657342657 0.074004517270201 0.14742169710175 GO:0043548 phosphatidylinositol 3-kinase binding 1/55 26/18639 0.0384615384615385 13.0342657342657 0.074004517270201 0.14742169710175 GO:0051139 metal cation:proton antiporter activity 1/55 26/18639 0.0384615384615385 13.0342657342657 0.074004517270201 0.14742169710175 GO:0005044 scavenger receptor activity 1/55 27/18639 0.037037037037037 12.5515151515152 0.076740763525514 0.15166875310948 GO:0046625 sphingolipid binding 1/55 28/18639 0.0357142857142857 12.1032467532468 0.0794690709619043 0.153436437011061 GO:0046875 ephrin receptor binding 1/55 28/18639 0.0357142857142857 12.1032467532468 0.0794690709619043 0.153436437011061 GO:0051019 mitogen-activated protein kinase binding 1/55 28/18639 0.0357142857142857 12.1032467532468 0.0794690709619043 0.153436437011061 GO:0015079 potassium ion transmembrane transporter activity 2/55 160/18639 0.0125 4.23613636363636 0.0809643575935803 0.153951903052457 GO:0005178 integrin binding 2/55 161/18639 0.0124223602484472 4.20982495765104 0.0818324429550571 0.153951903052457 GO:0051861 glycolipid binding 1/55 29/18639 0.0344827586206897 11.6858934169279 0.0821894621873673 0.153951903052457 GO:0099604 ligand-gated calcium channel activity 1/55 29/18639 0.0344827586206897 11.6858934169279 0.0821894621873673 0.153951903052457 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/55 349/18639 0.00859598853868195 2.91310237040896 0.0838443720228778 0.155550305813348 GO:0015081 sodium ion transmembrane transporter activity 2/55 164/18639 0.0121951219512195 4.13281596452328 0.0844541234157737 0.155550305813348 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/55 30/18639 0.0333333333333333 11.2963636363636 0.0849019597467277 0.155550305813348 GO:0016411 acylglycerol O-acyltransferase activity 1/55 31/18639 0.032258064516129 10.9319648093842 0.0876065861218109 0.158196065586867 GO:0070273 phosphatidylinositol-4-phosphate binding 1/55 31/18639 0.032258064516129 10.9319648093842 0.0876065861218109 0.158196065586867 GO:0043425 bHLH transcription factor binding 1/55 32/18639 0.03125 10.5903409090909 0.0903033637316188 0.161293382155064 GO:0106310 protein serine kinase activity 3/55 361/18639 0.00831024930747922 2.81626794258373 0.0906070393779441 0.161293382155064 GO:0042578 phosphoric ester hydrolase activity 3/55 363/18639 0.00826446280991736 2.8007513148009 0.0917560807509261 0.162188565271003 GO:0004721 phosphoprotein phosphatase activity 2/55 175/18639 0.0114285714285714 3.87303896103896 0.0942814626879882 0.165487042899895 GO:0008376 acetylgalactosaminyltransferase activity 1/55 34/18639 0.0294117647058824 9.96737967914439 0.0956734620183154 0.165614061838601 GO:0051427 hormone receptor binding 1/55 34/18639 0.0294117647058824 9.96737967914439 0.0956734620183154 0.165614061838601 GO:0043015 gamma-tubulin binding 1/55 35/18639 0.0285714285714286 9.6825974025974 0.0983468272206262 0.169075709810802 GO:1901981 phosphatidylinositol phosphate binding 2/55 185/18639 0.0108108108108108 3.6636855036855 0.103488634405181 0.174639231195953 GO:0019213 deacetylase activity 1/55 37/18639 0.027027027027027 9.15921375921376 0.103670300590426 0.174639231195953 GO:0043394 proteoglycan binding 1/55 37/18639 0.027027027027027 9.15921375921376 0.103670300590426 0.174639231195953 GO:0019902 phosphatase binding 2/55 190/18639 0.0105263157894737 3.56727272727273 0.10818258899474 0.181025532251198 GO:0030331 nuclear estrogen receptor binding 1/55 40/18639 0.025 8.47227272727273 0.111597698743815 0.185503459501308 GO:0042287 MHC protein binding 1/55 41/18639 0.024390243902439 8.26563192904656 0.114224836039857 0.188621275302659 GO:0035198 miRNA binding 1/55 42/18639 0.0238095238095238 8.06883116883117 0.11684434534289 0.191685821444872 GO:0005516 calmodulin binding 2/55 207/18639 0.00966183574879227 3.27430830039526 0.124550606241259 0.199292916674419 GO:0008009 chemokine activity 1/55 45/18639 0.0222222222222222 7.53090909090909 0.124657322382007 0.199292916674419 GO:0042605 peptide antigen binding 1/55 45/18639 0.0222222222222222 7.53090909090909 0.124657322382007 0.199292916674419 GO:0140303 intramembrane lipid transporter activity 1/55 45/18639 0.0222222222222222 7.53090909090909 0.124657322382007 0.199292916674419 GO:0030291 protein serine/threonine kinase inhibitor activity 1/55 46/18639 0.0217391304347826 7.36719367588933 0.127246536497797 0.202144814309791 GO:0140693 molecular condensate scaffold activity 1/55 48/18639 0.0208333333333333 7.06022727272727 0.132402426456345 0.209012635475111 GO:0004674 protein serine/threonine kinase activity 3/55 433/18639 0.0069284064665127 2.34797396598782 0.135575405982617 0.212683918135231 GO:0048020 CCR chemokine receptor binding 1/55 50/18639 0.02 6.77781818181818 0.13752840799723 0.214407642281395 GO:0003779 actin binding 3/55 443/18639 0.00677200902934537 2.2949722963267 0.142351887363236 0.219624463228672 GO:0005080 protein kinase C binding 1/55 52/18639 0.0192307692307692 6.51713286713287 0.142624651419416 0.219624463228672 GO:0005085 guanyl-nucleotide exchange factor activity 2/55 230/18639 0.00869565217391304 2.94687747035573 0.147564332880007 0.223316402672689 GO:0003925 G protein activity 1/55 54/18639 0.0185185185185185 6.27575757575758 0.147691326070384 0.223316402672689 GO:0140463 chromatin-protein adaptor activity 1/55 54/18639 0.0185185185185185 6.27575757575758 0.147691326070384 0.223316402672689 GO:0008374 O-acyltransferase activity 1/55 55/18639 0.0181818181818182 6.16165289256198 0.150213627768858 0.225770183053792 GO:0061980 regulatory RNA binding 1/55 58/18639 0.0172413793103448 5.84294670846395 0.157736641722372 0.235666054001877 GO:0070888 E-box binding 1/55 59/18639 0.0169491525423729 5.74391371340524 0.160229752141901 0.237974365607202 GO:0042393 histone binding 2/55 247/18639 0.00809716599190283 2.74405594405594 0.165098234647768 0.243762687626999 GO:0042277 peptide binding 2/55 249/18639 0.00803212851405622 2.72201533406353 0.167185784567252 0.245401356294622 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/55 484/18639 0.00619834710743802 2.10056348610068 0.171267407260812 0.249930925711999 GO:0038024 cargo receptor activity 1/55 65/18639 0.0153846153846154 5.21370629370629 0.175036973163093 0.252495863585841 GO:0160215 deacylase activity 1/55 65/18639 0.0153846153846154 5.21370629370629 0.175036973163093 0.252495863585841 GO:0001216 DNA-binding transcription activator activity 3/55 491/18639 0.00610997963340122 2.07061655249028 0.176369199428074 0.252963823179695 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/55 67/18639 0.0149253731343284 5.05807327001357 0.179915513783793 0.255689284088488 GO:0005543 phospholipid binding 3/55 497/18639 0.00603621730382294 2.04561916956283 0.180776835958005 0.255689284088488 GO:0005548 phospholipid transporter activity 1/55 68/18639 0.0147058823529412 4.98368983957219 0.182344150804141 0.255689284088488 GO:0030145 manganese ion binding 1/55 68/18639 0.0147058823529412 4.98368983957219 0.182344150804141 0.255689284088488 GO:0042379 chemokine receptor binding 1/55 72/18639 0.0138888888888889 4.70681818181818 0.191988281233028 0.267048026683405 GO:0016791 phosphatase activity 2/55 273/18639 0.00732600732600733 2.48271728271728 0.192572481393212 0.267048026683405 GO:0008017 microtubule binding 2/55 276/18639 0.0072463768115942 2.45573122529644 0.195783656523654 0.270009328502402 GO:0003725 double-stranded RNA binding 1/55 75/18639 0.0133333333333333 4.51854545454546 0.199148001709985 0.27166385015873 GO:0044183 protein folding chaperone 1/55 75/18639 0.0133333333333333 4.51854545454546 0.199148001709985 0.27166385015873 GO:0017022 myosin binding 1/55 76/18639 0.0131578947368421 4.45909090909091 0.201520704786151 0.273414577844995 GO:0015291 secondary active transmembrane transporter activity 2/55 287/18639 0.00696864111498258 2.36160912258473 0.207616201973775 0.280170251050632 GO:0001540 amyloid-beta binding 1/55 83/18639 0.0120481927710843 4.08302300109529 0.217937463859772 0.292525686785042 GO:0004527 exonuclease activity 1/55 84/18639 0.0119047619047619 4.03441558441558 0.220255497891229 0.294064521120736 GO:0008081 phosphoric diester hydrolase activity 1/55 87/18639 0.0114942528735632 3.89529780564263 0.22716920042868 0.301690313796819 GO:0043178 alcohol binding 1/55 92/18639 0.0108695652173913 3.68359683794466 0.23855852256328 0.315148364017807 GO:0051219 phosphoprotein binding 1/55 93/18639 0.010752688172043 3.64398826979472 0.240816530934393 0.31548794720207 GO:0022836 gated channel activity 2/55 318/18639 0.00628930817610063 2.13138936535163 0.241329425748197 0.31548794720207 GO:0016407 acetyltransferase activity 1/55 96/18639 0.0104166666666667 3.53011363636364 0.247551183579275 0.321944803515015 GO:0005249 voltage-gated potassium channel activity 1/55 98/18639 0.0102040816326531 3.45807050092764 0.252008328857315 0.326052013109206 GO:0003924 GTPase activity 2/55 331/18639 0.00604229607250755 2.04767920900851 0.255566081748886 0.328959418046002 GO:0005261 monoatomic cation channel activity 2/55 341/18639 0.00586510263929619 1.98762996534258 0.266534566337891 0.34132742934087 GO:0008013 beta-catenin binding 1/55 106/18639 0.00943396226415094 3.19708404802744 0.269579138519773 0.343473927758696 GO:0004620 phospholipase activity 1/55 109/18639 0.00917431192660551 3.10909090909091 0.276063172292418 0.349958869926247 GO:0004222 metalloendopeptidase activity 1/55 110/18639 0.00909090909090909 3.08082644628099 0.278211932439418 0.350910527850724 GO:0061630 ubiquitin protein ligase activity 2/55 353/18639 0.0056657223796034 1.9200618078805 0.279701211251014 0.351025020120023 GO:0017124 SH3 domain binding 1/55 115/18639 0.00869565217391304 2.94687747035573 0.288862157085868 0.360718415067428 GO:0019208 phosphatase regulator activity 1/55 117/18639 0.00854700854700855 2.8965034965035 0.293078910380366 0.36417230943303 GO:0046982 protein heterodimerization activity 2/55 369/18639 0.00542005420054201 1.83680709534368 0.297238100215397 0.36752100075894 GO:0061659 ubiquitin-like protein ligase activity 2/55 372/18639 0.00537634408602151 1.82199413489736 0.300521331371049 0.369759089088888 GO:0005267 potassium channel activity 1/55 124/18639 0.00806451612903226 2.73299120234604 0.307645121643947 0.376677685525028 GO:0016298 lipase activity 1/55 130/18639 0.00769230769230769 2.60685314685315 0.319895591598443 0.387892722179755 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/55 130/18639 0.00769230769230769 2.60685314685315 0.319895591598443 0.387892722179755 GO:0005262 calcium channel activity 1/55 131/18639 0.00763358778625954 2.58695350451076 0.32191654045911 0.38846659449633 GO:0099094 ligand-gated monoatomic cation channel activity 1/55 136/18639 0.00735294117647059 2.4918449197861 0.331933175232768 0.398637449681458 GO:0016922 nuclear receptor binding 1/55 137/18639 0.0072992700729927 2.47365627073656 0.333918997821656 0.39911270692017 GO:0030295 protein kinase activator activity 1/55 139/18639 0.00719424460431655 2.4380640941792 0.337873272117156 0.401925077257849 GO:0020037 heme binding 1/55 142/18639 0.00704225352112676 2.3865556978233 0.343761504705973 0.406246193048538 GO:0022843 voltage-gated monoatomic cation channel activity 1/55 143/18639 0.00699300699300699 2.36986649713922 0.345712800442642 0.406246193048538 GO:0019955 cytokine binding 1/55 144/18639 0.00694444444444444 2.35340909090909 0.347658399273506 0.406246193048538 GO:0004857 enzyme inhibitor activity 2/55 416/18639 0.00480769230769231 1.62928321678322 0.34832690468831 0.406246193048538 GO:0008194 UDP-glycosyltransferase activity 1/55 145/18639 0.00689655172413793 2.33717868338558 0.349598317523841 0.406246193048538 GO:0019209 kinase activator activity 1/55 148/18639 0.00675675675675676 2.28980343980344 0.355384151356681 0.411066460785839 GO:0046906 tetrapyrrole binding 1/55 152/18639 0.00657894736842105 2.22954545454545 0.363020050737092 0.417972627224817 GO:0005216 monoatomic ion channel activity 2/55 448/18639 0.00446428571428571 1.51290584415584 0.38246844819174 0.437566426332664 GO:0004842 ubiquitin-protein transferase activity 2/55 449/18639 0.0044543429844098 1.50953634338935 0.383524357741777 0.437566426332664 GO:0022804 active transmembrane transporter activity 2/55 457/18639 0.00437636761487965 1.48311119952258 0.391945072161907 0.445150285577551 GO:0008201 heparin binding 1/55 172/18639 0.00581395348837209 1.97029598308668 0.399887263297104 0.45006023661156 GO:0005244 voltage-gated monoatomic ion channel activity 1/55 173/18639 0.00578034682080925 1.95890698896479 0.401674570413509 0.45006023661156 GO:0140030 modification-dependent protein binding 1/55 173/18639 0.00578034682080925 1.95890698896479 0.401674570413509 0.45006023661156 GO:0003823 antigen binding 1/55 174/18639 0.00574712643678161 1.94764890282132 0.403456650919697 0.45006023661156 GO:0022832 voltage-gated channel activity 1/55 175/18639 0.00571428571428571 1.93651948051948 0.40523351981758 0.45006023661156 GO:0005319 lipid transporter activity 1/55 178/18639 0.00561797752808989 1.90388151174668 0.410533006247499 0.453937376952081 GO:0019787 ubiquitin-like protein transferase activity 2/55 479/18639 0.00417536534446764 1.41499335737332 0.414842834653235 0.456691015341939 GO:0008237 metallopeptidase activity 1/55 184/18639 0.00543478260869565 1.84179841897233 0.420993272019164 0.461187356574087 GO:0015078 proton transmembrane transporter activity 1/55 185/18639 0.00540540540540541 1.83184275184275 0.422718840701849 0.461187356574087 GO:0015276 ligand-gated monoatomic ion channel activity 1/55 186/18639 0.00537634408602151 1.82199413489736 0.424439360034319 0.461187356574087 GO:0022834 ligand-gated channel activity 1/55 188/18639 0.00531914893617021 1.80261121856867 0.427865308617945 0.462906001996139 GO:0016755 aminoacyltransferase activity 2/55 496/18639 0.00403225806451613 1.36649560117302 0.43225422098302 0.465647250930206 GO:0016758 hexosyltransferase activity 1/55 197/18639 0.0050761421319797 1.72025842178126 0.443035934229543 0.475222305519723 GO:0004518 nuclease activity 1/55 209/18639 0.00478468899521531 1.62148760330579 0.462650528830676 0.492056282781778 GO:0051015 actin filament binding 1/55 209/18639 0.00478468899521531 1.62148760330579 0.462650528830676 0.492056282781778 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/55 229/18639 0.00436681222707424 1.47987296546248 0.493844843358198 0.523017112586109 GO:0005125 cytokine activity 1/55 234/18639 0.00427350427350427 1.44825174825175 0.501361324340405 0.52874660676236 GO:0005539 glycosaminoglycan binding 1/55 242/18639 0.00413223140495868 1.40037565740045 0.513160335982901 0.538925708500871 GO:0033218 amide binding 1/55 247/18639 0.00404858299595142 1.37202797202797 0.520395057700428 0.544246497845032 GO:0003713 transcription coactivator activity 1/55 256/18639 0.00390625 1.32379261363636 0.533152497447404 0.555275007714931 GO:0016757 glycosyltransferase activity 1/55 267/18639 0.00374531835205993 1.26925434116445 0.548293106952377 0.568684172913416 GO:1901681 sulfur compound binding 1/55 275/18639 0.00363636363636364 1.2323305785124 0.559000599253498 0.577403911163078 GO:0031625 ubiquitin protein ligase binding 1/55 302/18639 0.0033112582781457 1.12215532811559 0.593330843194314 0.610352629679397 GO:0044389 ubiquitin-like protein ligase binding 1/55 322/18639 0.0031055900621118 1.05245623941276 0.61705528500074 0.632166843000759 GO:0045296 cadherin binding 1/55 334/18639 0.0029940119760479 1.01464344039194 0.63063198823978 0.643449711577986 GO:0005525 GTP binding 1/55 378/18639 0.00264550264550265 0.896536796536797 0.676488666976728 0.687443949033032 GO:0019001 guanyl nucleotide binding 1/55 400/18639 0.0025 0.847227272727273 0.697272069647571 0.702872648520243 GO:0032561 guanyl ribonucleotide binding 1/55 400/18639 0.0025 0.847227272727273 0.697272069647571 0.702872648520243 GO:0004175 endopeptidase activity 1/55 405/18639 0.00246913580246914 0.836767676767677 0.701809523934779 0.704616762030518 GO:0016887 ATP hydrolysis activity 1/55 417/18639 0.00239808153477218 0.812688031393067 0.712428739830206 0.712428739830206