ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005096 GTPase activator activity 12/194 271/18639 0.044280442804428 4.25434625480275 2.81639403866274e-05 0.0158562984376712 GO:0030695 GTPase regulator activity 15/194 489/18639 0.0306748466257669 2.9471570425653 0.000192476399644424 0.0369258715869618 GO:0060589 nucleoside-triphosphatase regulator activity 15/194 490/18639 0.0306122448979592 2.94114243635599 0.000196763081280436 0.0369258715869618 GO:0022851 GABA-gated chloride ion channel activity 3/194 18/18639 0.166666666666667 16.0128865979381 0.000807334047373744 0.0822231999565562 GO:0050811 GABA receptor binding 3/194 18/18639 0.166666666666667 16.0128865979381 0.000807334047373744 0.0822231999565562 GO:0004890 GABA-A receptor activity 3/194 19/18639 0.157894736842105 15.1701030927835 0.000951392958564711 0.0822231999565562 GO:0048156 tau protein binding 4/194 43/18639 0.0930232558139535 8.93742507791896 0.00102231332095185 0.0822231999565562 GO:0050321 tau-protein kinase activity 3/194 22/18639 0.136363636363636 13.1014526710403 0.00147769869340398 0.103993045548305 GO:0016917 GABA receptor activity 3/194 23/18639 0.130434782608696 12.5318242940385 0.00168641078006565 0.105494363241885 GO:0008139 nuclear localization sequence binding 3/194 25/18639 0.12 11.5292783505155 0.00215693420867065 0.112740319515319 GO:0051018 protein kinase A binding 4/194 53/18639 0.0754716981132075 7.25111845944369 0.00223747573350588 0.112740319515319 GO:0003779 actin binding 12/194 443/18639 0.0270880361173815 2.60254590305089 0.00240299082448281 0.112740319515319 GO:0070097 delta-catenin binding 2/194 10/18639 0.2 19.2154639175258 0.00459065638522035 0.198810734221466 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/194 11/18639 0.181818181818182 17.4686035613871 0.00557252251123124 0.200359067845879 GO:0008503 benzodiazepine receptor activity 2/194 11/18639 0.181818181818182 17.4686035613871 0.00557252251123124 0.200359067845879 GO:0051020 GTPase binding 9/194 315/18639 0.0285714285714286 2.74506627393225 0.00586289457872081 0.200359067845879 GO:0005516 calmodulin binding 7/194 207/18639 0.0338164251207729 3.24899148363962 0.00604991856728232 0.200359067845879 GO:0098631 cell adhesion mediator activity 4/194 76/18639 0.0526315789473684 5.05670103092783 0.00814947900862431 0.254897593436416 GO:0005545 1-phosphatidylinositol binding 2/194 14/18639 0.142857142857143 13.7253313696613 0.00903287925655216 0.267658474812572 GO:0031267 small GTPase binding 8/194 283/18639 0.0282685512367491 2.71596663145241 0.0097529686431577 0.274546067304889 GO:0099095 ligand-gated monoatomic anion channel activity 3/194 47/18639 0.0638297872340425 6.13259486729546 0.0128670175584731 0.329868757392664 GO:0004197 cysteine-type endopeptidase activity 4/194 88/18639 0.0454545454545455 4.36715089034677 0.0134590751862949 0.329868757392664 GO:0140857 histone H3T45 kinase activity 7/194 246/18639 0.0284552845528455 2.73390746794066 0.014732803044048 0.329868757392664 GO:0004679 AMP-activated protein kinase activity 7/194 248/18639 0.0282258064516129 2.71185982707017 0.0153383181585888 0.329868757392664 GO:0004674 protein serine/threonine kinase activity 10/194 433/18639 0.023094688221709 2.21887574105378 0.015521788622855 0.329868757392664 GO:0005048 signal sequence binding 3/194 51/18639 0.0588235294117647 5.6516070345664 0.0160341035490358 0.329868757392664 GO:0046624 sphingolipid transporter activity 2/194 19/18639 0.105263157894737 10.1134020618557 0.0164055509893332 0.329868757392664 GO:1990380 K48-linked deubiquitinase activity 2/194 19/18639 0.105263157894737 10.1134020618557 0.0164055509893332 0.329868757392664 GO:0061608 nuclear import signal receptor activity 2/194 20/18639 0.1 9.60773195876289 0.0181049734991255 0.351486209655437 GO:0070034 telomerase RNA binding 2/194 22/18639 0.0909090909090909 8.73430178069353 0.0217151618047597 0.355759916453094 GO:0140103 catalytic activity, acting on a glycoprotein 2/194 23/18639 0.0869565217391304 8.35454952935903 0.0236226619023496 0.355759916453094 GO:0008013 beta-catenin binding 4/194 106/18639 0.0377358490566038 3.62555922972184 0.0248542427280103 0.355759916453094 GO:0022824 transmitter-gated monoatomic ion channel activity 3/194 63/18639 0.0476190476190476 4.57511045655376 0.0279405951120179 0.355759916453094 GO:0022835 transmitter-gated channel activity 3/194 63/18639 0.0476190476190476 4.57511045655376 0.0279405951120179 0.355759916453094 GO:0004435 phosphatidylinositol phospholipase C activity 2/194 26/18639 0.0769230769230769 7.39056304520222 0.0297357356840462 0.355759916453094 GO:0008143 poly(A) binding 2/194 26/18639 0.0769230769230769 7.39056304520222 0.0297357356840462 0.355759916453094 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 8/194 349/18639 0.0229226361031519 2.20234543467344 0.0300564157179487 0.355759916453094 GO:0141003 histone H2AX kinase activity 8/194 354/18639 0.0225988700564972 2.17123886073738 0.0322988392394911 0.355759916453094 GO:0140996 histone H3 kinase activity 8/194 357/18639 0.0224089635854342 2.1529931560253 0.0336979142928164 0.355759916453094 GO:0003712 transcription coregulator activity 10/194 495/18639 0.0202020202020202 1.94095595126523 0.0347980501770116 0.355759916453094 GO:0140030 modification-dependent protein binding 5/194 173/18639 0.0289017341040462 2.77680114415112 0.0348883836250425 0.355759916453094 GO:0035173 histone kinase activity 8/194 360/18639 0.0222222222222222 2.13505154639175 0.035137766716023 0.355759916453094 GO:0106310 protein serine kinase activity 8/194 361/18639 0.0221606648199446 2.12913727618014 0.0356268557576935 0.355759916453094 GO:0004629 phospholipase C activity 2/194 29/18639 0.0689655172413793 6.62602204052613 0.0364025218210884 0.355759916453094 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/194 73/18639 0.0410958904109589 3.94838299675187 0.0406136208325074 0.355759916453094 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 6/194 243/18639 0.0246913580246914 2.37227949599084 0.0420106399936947 0.355759916453094 GO:0004676 3-phosphoinositide-dependent protein kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0004711 ribosomal protein S6 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0035175 histone H3S10 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0035979 histone H2AXS139 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0044022 histone H3S28 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0044023 histone H4S1 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0044024 histone H2AS1 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0044025 histone H2BS14 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0072354 histone H3T3 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0072371 histone H2AS121 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0072518 Rho-dependent protein serine/threonine kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0140823 histone H2BS36 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0140855 histone H3S57 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0140995 histone H2A kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0140997 histone H4 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0140998 histone H2B kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:1990244 histone H2AT120 kinase activity 6/194 245/18639 0.0244897959183673 2.35291394908479 0.0434230190484343 0.355759916453094 GO:0051059 NF-kappaB binding 2/194 32/18639 0.0625 6.0048324742268 0.0435833314270375 0.355759916453094 GO:0070717 poly-purine tract binding 2/194 32/18639 0.0625 6.0048324742268 0.0435833314270375 0.355759916453094 GO:0140142 nucleocytoplasmic carrier activity 2/194 32/18639 0.0625 6.0048324742268 0.0435833314270375 0.355759916453094 GO:0019783 ubiquitin-like protein peptidase activity 4/194 127/18639 0.031496062992126 3.02605730984658 0.0438206557890704 0.355759916453094 GO:0004677 DNA-dependent protein kinase activity 6/194 246/18639 0.024390243902439 2.34334925823485 0.0441402744485439 0.355759916453094 GO:0035402 histone H3T11 kinase activity 6/194 247/18639 0.0242914979757085 2.33386201427439 0.0448649272969266 0.355759916453094 GO:0035403 histone H3T6 kinase activity 6/194 247/18639 0.0242914979757085 2.33386201427439 0.0448649272969266 0.355759916453094 GO:0042393 histone binding 6/194 247/18639 0.0242914979757085 2.33386201427439 0.0448649272969266 0.355759916453094 GO:0046943 carboxylic acid transmembrane transporter activity 5/194 188/18639 0.0265957446808511 2.55524786137311 0.0470256530210601 0.365104527925649 GO:0005342 organic acid transmembrane transporter activity 5/194 189/18639 0.0264550264550265 2.54172803141875 0.0479135146211298 0.365104527925649 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/194 34/18639 0.0588235294117647 5.6516070345664 0.048637370505193 0.365104527925649 GO:0090482 vitamin transmembrane transporter activity 2/194 34/18639 0.0588235294117647 5.6516070345664 0.048637370505193 0.365104527925649 GO:0005343 organic acid:sodium symporter activity 2/194 35/18639 0.0571428571428571 5.49013254786451 0.051240377941632 0.379583326067616 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/194 36/18639 0.0555555555555556 5.33762886597938 0.0538922903263658 0.394043629269402 GO:0005254 chloride channel activity 3/194 83/18639 0.036144578313253 3.47267420196249 0.0557059876688658 0.402082962276557 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/194 38/18639 0.0526315789473684 5.05670103092783 0.0593376984411734 0.422874990156717 GO:0045296 cadherin binding 7/194 334/18639 0.0209580838323353 2.0135965183036 0.0607604102736965 0.427601387301139 GO:0003714 transcription corepressor activity 5/194 204/18639 0.0245098039215686 2.35483626440267 0.0624218330603109 0.430499456740697 GO:0008514 organic anion transmembrane transporter activity 6/194 269/18639 0.0223048327137546 2.142988540988 0.06270151945424 0.430499456740697 GO:0004532 RNA exonuclease activity 2/194 40/18639 0.05 4.80386597938144 0.0649635427679581 0.44065632022121 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 9/194 484/18639 0.0185950413223141 1.78656172786913 0.0669545978351351 0.444122405692321 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/194 41/18639 0.0487804878048781 4.6866985164697 0.0678410779565535 0.444122405692321 GO:0017080 sodium channel regulator activity 2/194 41/18639 0.0487804878048781 4.6866985164697 0.0678410779565535 0.444122405692321 GO:0140297 DNA-binding transcription factor binding 9/194 488/18639 0.0184426229508197 1.77191777928004 0.0697068737619961 0.45109160836786 GO:0048487 beta-tubulin binding 2/194 42/18639 0.0476190476190476 4.57511045655376 0.0707601020719594 0.45270383484674 GO:0001216 DNA-binding transcription activator activity 9/194 491/18639 0.0183299389002037 1.76109139773658 0.0718170497973592 0.454067904401877 GO:0030594 neurotransmitter receptor activity 3/194 97/18639 0.0309278350515464 2.97146349240089 0.0806265523653813 0.454067904401877 GO:0140359 ABC-type transporter activity 2/194 47/18639 0.0425531914893617 4.08839657819697 0.085937460022511 0.454067904401877 GO:0099106 ion channel regulator activity 4/194 160/18639 0.025 2.40193298969072 0.0862103552570348 0.454067904401877 GO:0005253 monoatomic anion channel activity 3/194 103/18639 0.029126213592233 2.79836853167851 0.0925503991629278 0.454067904401877 GO:0005085 guanyl-nucleotide exchange factor activity 5/194 230/18639 0.0217391304347826 2.08863738233976 0.0928026392899229 0.454067904401877 GO:0015103 inorganic anion transmembrane transporter activity 4/194 165/18639 0.0242424242424242 2.32914714151828 0.0939141020785394 0.454067904401877 GO:0005201 extracellular matrix structural constituent 4/194 168/18639 0.0238095238095238 2.28755522827688 0.0986881120525701 0.454067904401877 GO:0016247 channel regulator activity 4/194 168/18639 0.0238095238095238 2.28755522827688 0.0986881120525701 0.454067904401877 GO:0005021 vascular endothelial growth factor receptor activity 2/194 51/18639 0.0392156862745098 3.76773802304427 0.09871241806156 0.454067904401877 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0015187 glycine transmembrane transporter activity 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0030957 Tat protein binding 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0051880 G-quadruplex DNA binding 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0099122 RNA polymerase II C-terminal domain binding 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0140999 histone H3K4 trimethyltransferase activity 1/194 10/18639 0.1 9.60773195876289 0.0993636307969142 0.454067904401877 GO:0141108 transporter regulator activity 4/194 170/18639 0.0235294117647059 2.26064281382656 0.101932729841992 0.454067904401877 GO:0005080 protein kinase C binding 2/194 52/18639 0.0384615384615385 3.69528152260111 0.101985390460468 0.454067904401877 GO:0030159 signaling receptor complex adaptor activity 2/194 52/18639 0.0384615384615385 3.69528152260111 0.101985390460468 0.454067904401877 GO:0004843 cysteine-type deubiquitinase activity 3/194 108/18639 0.0277777777777778 2.66881443298969 0.103009154760387 0.454067904401877 GO:0004620 phospholipase activity 3/194 109/18639 0.0275229357798165 2.64432989690722 0.105155222218004 0.454067904401877 GO:0008201 heparin binding 4/194 172/18639 0.0232558139534884 2.23435626947974 0.105226146279299 0.454067904401877 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/194 53/18639 0.0377358490566038 3.62555922972184 0.105288066712635 0.454067904401877 GO:0140463 chromatin-protein adaptor activity 2/194 54/18639 0.037037037037037 3.55841924398625 0.108619482035651 0.454067904401877 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/194 11/18639 0.0909090909090909 8.73430178069353 0.108742741625482 0.454067904401877 GO:0015217 ADP transmembrane transporter activity 1/194 11/18639 0.0909090909090909 8.73430178069353 0.108742741625482 0.454067904401877 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/194 11/18639 0.0909090909090909 8.73430178069353 0.108742741625482 0.454067904401877 GO:0019206 nucleoside kinase activity 1/194 11/18639 0.0909090909090909 8.73430178069353 0.108742741625482 0.454067904401877 GO:0032050 clathrin heavy chain binding 1/194 11/18639 0.0909090909090909 8.73430178069353 0.108742741625482 0.454067904401877 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/194 11/18639 0.0909090909090909 8.73430178069353 0.108742741625482 0.454067904401877 GO:0097493 structural molecule activity conferring elasticity 1/194 11/18639 0.0909090909090909 8.73430178069353 0.108742741625482 0.454067904401877 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/194 11/18639 0.0909090909090909 8.73430178069353 0.108742741625482 0.454067904401877 GO:0098632 cell-cell adhesion mediator activity 2/194 55/18639 0.0363636363636364 3.49372071227741 0.1119786883239 0.454067904401877 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/194 56/18639 0.0357142857142857 3.43133284241532 0.115364753908932 0.454067904401877 GO:0005078 MAP-kinase scaffold activity 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0008603 cAMP-dependent protein kinase regulator activity 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0016208 AMP binding 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0034452 dynactin binding 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0070410 co-SMAD binding 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0070679 inositol 1,4,5 trisphosphate binding 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/194 12/18639 0.0833333333333333 8.00644329896907 0.118024677857212 0.454067904401877 GO:0101005 deubiquitinase activity 3/194 115/18639 0.0260869565217391 2.50636485880771 0.118392781766506 0.454067904401877 GO:0061980 regulatory RNA binding 2/194 58/18639 0.0344827586206897 3.31301102026306 0.122213817065537 0.454067904401877 GO:0031593 polyubiquitin modification-dependent protein binding 2/194 59/18639 0.0338983050847458 3.25685829110606 0.125675031373092 0.454067904401877 GO:0070063 RNA polymerase binding 2/194 59/18639 0.0338983050847458 3.25685829110606 0.125675031373092 0.454067904401877 GO:0004535 poly(A)-specific ribonuclease activity 1/194 13/18639 0.0769230769230769 7.39056304520222 0.127210441130724 0.454067904401877 GO:0008417 fucosyltransferase activity 1/194 13/18639 0.0769230769230769 7.39056304520222 0.127210441130724 0.454067904401877 GO:0017154 semaphorin receptor activity 1/194 13/18639 0.0769230769230769 7.39056304520222 0.127210441130724 0.454067904401877 GO:0061459 L-arginine transmembrane transporter activity 1/194 13/18639 0.0769230769230769 7.39056304520222 0.127210441130724 0.454067904401877 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/194 13/18639 0.0769230769230769 7.39056304520222 0.127210441130724 0.454067904401877 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/194 13/18639 0.0769230769230769 7.39056304520222 0.127210441130724 0.454067904401877 GO:1901981 phosphatidylinositol phosphate binding 4/194 185/18639 0.0216216216216216 2.07734745054333 0.127774959717368 0.454067904401877 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/194 60/18639 0.0333333333333333 3.20257731958763 0.12915953799177 0.454067904401877 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/194 60/18639 0.0333333333333333 3.20257731958763 0.12915953799177 0.454067904401877 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/194 60/18639 0.0333333333333333 3.20257731958763 0.12915953799177 0.454067904401877 GO:0003713 transcription coactivator activity 5/194 256/18639 0.01953125 1.87651014819588 0.129467237344892 0.454067904401877 GO:0008234 cysteine-type peptidase activity 4/194 187/18639 0.0213903743315508 2.05512983075142 0.131411877165825 0.454067904401877 GO:0003697 single-stranded DNA binding 3/194 121/18639 0.0247933884297521 2.38208230382551 0.132213448496246 0.454067904401877 GO:0015108 chloride transmembrane transporter activity 3/194 121/18639 0.0247933884297521 2.38208230382551 0.132213448496246 0.454067904401877 GO:0015026 coreceptor activity 2/194 61/18639 0.0327868852459016 3.15007605205341 0.132666483953046 0.454067904401877 GO:0016836 hydro-lyase activity 2/194 61/18639 0.0327868852459016 3.15007605205341 0.132666483953046 0.454067904401877 GO:0015179 L-amino acid transmembrane transporter activity 2/194 62/18639 0.032258064516129 3.09926837379448 0.136195031352376 0.454067904401877 GO:0005161 platelet-derived growth factor receptor binding 1/194 14/18639 0.0714285714285714 6.86266568483063 0.136301022813352 0.454067904401877 GO:0005347 ATP transmembrane transporter activity 1/194 14/18639 0.0714285714285714 6.86266568483063 0.136301022813352 0.454067904401877 GO:0008559 ABC-type xenobiotic transporter activity 1/194 14/18639 0.0714285714285714 6.86266568483063 0.136301022813352 0.454067904401877 GO:0019992 diacylglycerol binding 1/194 14/18639 0.0714285714285714 6.86266568483063 0.136301022813352 0.454067904401877 GO:0034236 protein kinase A catalytic subunit binding 1/194 14/18639 0.0714285714285714 6.86266568483063 0.136301022813352 0.454067904401877 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/194 14/18639 0.0714285714285714 6.86266568483063 0.136301022813352 0.454067904401877 GO:0043176 amine binding 1/194 14/18639 0.0714285714285714 6.86266568483063 0.136301022813352 0.454067904401877 GO:0070742 C2H2 zinc finger domain binding 1/194 14/18639 0.0714285714285714 6.86266568483063 0.136301022813352 0.454067904401877 GO:0004089 carbonate dehydratase activity 1/194 15/18639 0.0666666666666667 6.40515463917526 0.145297404105927 0.45605923171622 GO:0004559 alpha-mannosidase activity 1/194 15/18639 0.0666666666666667 6.40515463917526 0.145297404105927 0.45605923171622 GO:0005041 low-density lipoprotein particle receptor activity 1/194 15/18639 0.0666666666666667 6.40515463917526 0.145297404105927 0.45605923171622 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/194 15/18639 0.0666666666666667 6.40515463917526 0.145297404105927 0.45605923171622 GO:0005523 tropomyosin binding 1/194 15/18639 0.0666666666666667 6.40515463917526 0.145297404105927 0.45605923171622 GO:0051371 muscle alpha-actinin binding 1/194 15/18639 0.0666666666666667 6.40515463917526 0.145297404105927 0.45605923171622 GO:0061578 K63-linked deubiquitinase activity 1/194 15/18639 0.0666666666666667 6.40515463917526 0.145297404105927 0.45605923171622 GO:0120283 protein serine/threonine kinase binding 1/194 15/18639 0.0666666666666667 6.40515463917526 0.145297404105927 0.45605923171622 GO:0016887 ATP hydrolysis activity 7/194 417/18639 0.0167865707434053 1.61280872209449 0.145690625801252 0.45605923171622 GO:0035591 signaling adaptor activity 3/194 129/18639 0.0232558139534884 2.23435626947974 0.151460916154595 0.45605923171622 GO:0016298 lipase activity 3/194 130/18639 0.0230769230769231 2.21716891356067 0.153927461317919 0.45605923171622 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0005521 lamin binding 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0015562 efflux transmembrane transporter activity 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0015923 mannosidase activity 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0022858 alanine transmembrane transporter activity 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0043023 ribosomal large subunit binding 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0140327 flippase activity 1/194 16/18639 0.0625 6.0048324742268 0.154200556146491 0.45605923171622 GO:0098960 postsynaptic neurotransmitter receptor activity 2/194 69/18639 0.0289855072463768 2.78484984311968 0.161432383261706 0.45605923171622 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/194 17/18639 0.0588235294117647 5.6516070345664 0.163011440112961 0.45605923171622 GO:0004659 prenyltransferase activity 1/194 17/18639 0.0588235294117647 5.6516070345664 0.163011440112961 0.45605923171622 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/194 17/18639 0.0588235294117647 5.6516070345664 0.163011440112961 0.45605923171622 GO:0008429 phosphatidylethanolamine binding 1/194 17/18639 0.0588235294117647 5.6516070345664 0.163011440112961 0.45605923171622 GO:0031489 myosin V binding 1/194 17/18639 0.0588235294117647 5.6516070345664 0.163011440112961 0.45605923171622 GO:1990226 histone methyltransferase binding 1/194 17/18639 0.0588235294117647 5.6516070345664 0.163011440112961 0.45605923171622 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/194 70/18639 0.0285714285714286 2.74506627393225 0.165105314504422 0.45605923171622 GO:0097110 scaffold protein binding 2/194 70/18639 0.0285714285714286 2.74506627393225 0.165105314504422 0.45605923171622 GO:0140299 molecular sensor activity 2/194 71/18639 0.028169014084507 2.7064033686656 0.168792948812589 0.45605923171622 GO:0002020 protease binding 3/194 136/18639 0.0220588235294118 2.1193526379624 0.168985050592232 0.45605923171622 GO:0044325 transmembrane transporter binding 3/194 136/18639 0.0220588235294118 2.1193526379624 0.168985050592232 0.45605923171622 GO:0016922 nuclear receptor binding 3/194 137/18639 0.0218978102189781 2.103882910678 0.171535534717204 0.45605923171622 GO:0000900 mRNA regulatory element binding translation repressor activity 1/194 18/18639 0.0555555555555556 5.33762886597938 0.171731007324758 0.45605923171622 GO:0008409 5'-3' exonuclease activity 1/194 18/18639 0.0555555555555556 5.33762886597938 0.171731007324758 0.45605923171622 GO:0017075 syntaxin-1 binding 1/194 18/18639 0.0555555555555556 5.33762886597938 0.171731007324758 0.45605923171622 GO:0030228 lipoprotein particle receptor activity 1/194 18/18639 0.0555555555555556 5.33762886597938 0.171731007324758 0.45605923171622 GO:0031690 adrenergic receptor binding 1/194 18/18639 0.0555555555555556 5.33762886597938 0.171731007324758 0.45605923171622 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/194 18/18639 0.0555555555555556 5.33762886597938 0.171731007324758 0.45605923171622 GO:0070628 proteasome binding 1/194 18/18639 0.0555555555555556 5.33762886597938 0.171731007324758 0.45605923171622 GO:0098641 cadherin binding involved in cell-cell adhesion 1/194 18/18639 0.0555555555555556 5.33762886597938 0.171731007324758 0.45605923171622 GO:1990381 ubiquitin-specific protease binding 1/194 18/18639 0.0555555555555556 5.33762886597938 0.171731007324758 0.45605923171622 GO:0051015 actin filament binding 4/194 209/18639 0.0191387559808612 1.83880037488285 0.174050207488851 0.457399965001486 GO:0035091 phosphatidylinositol binding 5/194 284/18639 0.0176056338028169 1.691502105416 0.175132909111489 0.457399965001486 GO:0004713 protein tyrosine kinase activity 3/194 140/18639 0.0214285714285714 2.05879970544919 0.179252463670179 0.457399965001486 GO:0035064 methylated histone binding 2/194 74/18639 0.027027027027027 2.59668431317916 0.179937145846354 0.457399965001486 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/194 19/18639 0.0526315789473684 5.05670103092783 0.180360199343393 0.457399965001486 GO:0008574 plus-end-directed microtubule motor activity 1/194 19/18639 0.0526315789473684 5.05670103092783 0.180360199343393 0.457399965001486 GO:0015245 fatty acid transmembrane transporter activity 1/194 19/18639 0.0526315789473684 5.05670103092783 0.180360199343393 0.457399965001486 GO:0030506 ankyrin binding 1/194 19/18639 0.0526315789473684 5.05670103092783 0.180360199343393 0.457399965001486 GO:0042800 histone H3K4 methyltransferase activity 1/194 19/18639 0.0526315789473684 5.05670103092783 0.180360199343393 0.457399965001486 GO:0140036 ubiquitin-modified protein reader activity 1/194 19/18639 0.0526315789473684 5.05670103092783 0.180360199343393 0.457399965001486 GO:0017022 myosin binding 2/194 76/18639 0.0263157894736842 2.52835051546392 0.18742765229556 0.471079322510716 GO:0140034 methylation-dependent protein binding 2/194 76/18639 0.0263157894736842 2.52835051546392 0.18742765229556 0.471079322510716 GO:0019199 transmembrane receptor protein kinase activity 2/194 78/18639 0.0256410256410256 2.46352101506741 0.194960965178373 0.479267912577322 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/194 21/18639 0.0476190476190476 4.57511045655376 0.19735117585409 0.479267912577322 GO:0015174 basic amino acid transmembrane transporter activity 1/194 21/18639 0.0476190476190476 4.57511045655376 0.19735117585409 0.479267912577322 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/194 21/18639 0.0476190476190476 4.57511045655376 0.19735117585409 0.479267912577322 GO:0051010 microtubule plus-end binding 1/194 21/18639 0.0476190476190476 4.57511045655376 0.19735117585409 0.479267912577322 GO:0061891 calcium ion sensor activity 1/194 21/18639 0.0476190476190476 4.57511045655376 0.19735117585409 0.479267912577322 GO:0015370 solute:sodium symporter activity 2/194 79/18639 0.0253164556962025 2.4323372047501 0.198742119500925 0.479267912577322 GO:0016835 carbon-oxygen lyase activity 2/194 79/18639 0.0253164556962025 2.4323372047501 0.198742119500925 0.479267912577322 GO:0046332 SMAD binding 2/194 79/18639 0.0253164556962025 2.4323372047501 0.198742119500925 0.479267912577322 GO:0008509 monoatomic anion transmembrane transporter activity 3/194 149/18639 0.0201342281879195 1.93444267626098 0.20293935697281 0.479267912577322 GO:0008093 cytoskeletal anchor activity 1/194 22/18639 0.0454545454545455 4.36715089034677 0.205714795570725 0.479267912577322 GO:0140035 ubiquitin-like protein reader activity 1/194 22/18639 0.0454545454545455 4.36715089034677 0.205714795570725 0.479267912577322 GO:0140517 protein-RNA adaptor activity 1/194 22/18639 0.0454545454545455 4.36715089034677 0.205714795570725 0.479267912577322 GO:0140784 metal ion sensor activity 1/194 22/18639 0.0454545454545455 4.36715089034677 0.205714795570725 0.479267912577322 GO:0001618 virus receptor activity 2/194 81/18639 0.0246913580246914 2.37227949599084 0.206330416471131 0.479267912577322 GO:0015101 organic cation transmembrane transporter activity 2/194 81/18639 0.0246913580246914 2.37227949599084 0.206330416471131 0.479267912577322 GO:0140272 exogenous protein binding 2/194 82/18639 0.024390243902439 2.34334925823485 0.210136390160529 0.479267912577322 GO:0030165 PDZ domain binding 2/194 83/18639 0.0240963855421687 2.31511613464166 0.213949486518347 0.479267912577322 GO:0000295 adenine nucleotide transmembrane transporter activity 1/194 23/18639 0.0434782608695652 4.17727476467952 0.21399171073747 0.479267912577322 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/194 23/18639 0.0434782608695652 4.17727476467952 0.21399171073747 0.479267912577322 GO:0005158 insulin receptor binding 1/194 23/18639 0.0434782608695652 4.17727476467952 0.21399171073747 0.479267912577322 GO:0005283 amino acid:sodium symporter activity 1/194 23/18639 0.0434782608695652 4.17727476467952 0.21399171073747 0.479267912577322 GO:0042171 lysophosphatidic acid acyltransferase activity 1/194 23/18639 0.0434782608695652 4.17727476467952 0.21399171073747 0.479267912577322 GO:0070577 lysine-acetylated histone binding 1/194 23/18639 0.0434782608695652 4.17727476467952 0.21399171073747 0.479267912577322 GO:0071617 lysophospholipid acyltransferase activity 1/194 23/18639 0.0434782608695652 4.17727476467952 0.21399171073747 0.479267912577322 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/194 23/18639 0.0434782608695652 4.17727476467952 0.21399171073747 0.479267912577322 GO:0004527 exonuclease activity 2/194 84/18639 0.0238095238095238 2.28755522827688 0.217769148573448 0.479267912577322 GO:0051117 ATPase binding 2/194 84/18639 0.0238095238095238 2.28755522827688 0.217769148573448 0.479267912577322 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/194 24/18639 0.0416666666666667 4.00322164948454 0.222182815599789 0.479267912577322 GO:0004622 lysophospholipase activity 1/194 24/18639 0.0416666666666667 4.00322164948454 0.222182815599789 0.479267912577322 GO:0005315 phosphate transmembrane transporter activity 1/194 24/18639 0.0416666666666667 4.00322164948454 0.222182815599789 0.479267912577322 GO:0030215 semaphorin receptor binding 1/194 24/18639 0.0416666666666667 4.00322164948454 0.222182815599789 0.479267912577322 GO:0030552 cAMP binding 1/194 24/18639 0.0416666666666667 4.00322164948454 0.222182815599789 0.479267912577322 GO:0050699 WW domain binding 1/194 24/18639 0.0416666666666667 4.00322164948454 0.222182815599789 0.479267912577322 GO:0070300 phosphatidic acid binding 1/194 24/18639 0.0416666666666667 4.00322164948454 0.222182815599789 0.479267912577322 GO:0140033 acetylation-dependent protein binding 1/194 24/18639 0.0416666666666667 4.00322164948454 0.222182815599789 0.479267912577322 GO:0140612 DNA damage sensor activity 1/194 24/18639 0.0416666666666667 4.00322164948454 0.222182815599789 0.479267912577322 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/194 86/18639 0.0232558139534884 2.23435626947974 0.225425995270227 0.482565913829422 GO:0050660 flavin adenine dinucleotide binding 2/194 86/18639 0.0232558139534884 2.23435626947974 0.225425995270227 0.482565913829422 GO:0008081 phosphoric diester hydrolase activity 2/194 87/18639 0.0229885057471264 2.20867401350871 0.229262118869288 0.483778747437303 GO:0004709 MAP kinase kinase kinase activity 1/194 25/18639 0.04 3.84309278350515 0.230288995227704 0.483778747437303 GO:0017056 structural constituent of nuclear pore 1/194 25/18639 0.04 3.84309278350515 0.230288995227704 0.483778747437303 GO:0047617 fatty acyl-CoA hydrolase activity 1/194 25/18639 0.04 3.84309278350515 0.230288995227704 0.483778747437303 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/194 25/18639 0.04 3.84309278350515 0.230288995227704 0.483778747437303 GO:0003727 single-stranded RNA binding 2/194 89/18639 0.0224719101123595 2.15904088960964 0.236947190943476 0.484365211978774 GO:0005160 transforming growth factor beta receptor binding 1/194 26/18639 0.0384615384615385 3.69528152260111 0.23831112560945 0.484365211978774 GO:0015145 monosaccharide transmembrane transporter activity 1/194 26/18639 0.0384615384615385 3.69528152260111 0.23831112560945 0.484365211978774 GO:0015216 purine nucleotide transmembrane transporter activity 1/194 26/18639 0.0384615384615385 3.69528152260111 0.23831112560945 0.484365211978774 GO:0016289 acyl-CoA hydrolase activity 1/194 26/18639 0.0384615384615385 3.69528152260111 0.23831112560945 0.484365211978774 GO:0030507 spectrin binding 1/194 26/18639 0.0384615384615385 3.69528152260111 0.23831112560945 0.484365211978774 GO:0043548 phosphatidylinositol 3-kinase binding 1/194 26/18639 0.0384615384615385 3.69528152260111 0.23831112560945 0.484365211978774 GO:0050681 nuclear androgen receptor binding 1/194 26/18639 0.0384615384615385 3.69528152260111 0.23831112560945 0.484365211978774 GO:0050750 low-density lipoprotein particle receptor binding 1/194 26/18639 0.0384615384615385 3.69528152260111 0.23831112560945 0.484365211978774 GO:0005539 glycosaminoglycan binding 4/194 242/18639 0.0165289256198347 1.58805486921701 0.245209731850387 0.491626920276504 GO:0001671 ATPase activator activity 1/194 27/18639 0.037037037037037 3.55841924398625 0.246250073744182 0.491626920276504 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/194 27/18639 0.037037037037037 3.55841924398625 0.246250073744182 0.491626920276504 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/194 27/18639 0.037037037037037 3.55841924398625 0.246250073744182 0.491626920276504 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/194 27/18639 0.037037037037037 3.55841924398625 0.246250073744182 0.491626920276504 GO:0045499 chemorepellent activity 1/194 28/18639 0.0357142857142857 3.43133284241532 0.254106697733739 0.501972178330157 GO:0051119 sugar transmembrane transporter activity 1/194 28/18639 0.0357142857142857 3.43133284241532 0.254106697733739 0.501972178330157 GO:0051393 alpha-actinin binding 1/194 28/18639 0.0357142857142857 3.43133284241532 0.254106697733739 0.501972178330157 GO:0042562 hormone binding 2/194 94/18639 0.0212765957446809 2.04419828909849 0.256211801992897 0.503206415664734 GO:0042277 peptide binding 4/194 249/18639 0.0160642570281124 1.54341075642777 0.261097777227072 0.503206415664734 GO:0005543 phospholipid binding 7/194 497/18639 0.0140845070422535 1.3532016843328 0.261122482764314 0.503206415664734 GO:0003785 actin monomer binding 1/194 29/18639 0.0344827586206897 3.31301102026306 0.261881846873476 0.503206415664734 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/194 29/18639 0.0344827586206897 3.31301102026306 0.261881846873476 0.503206415664734 GO:0005416 amino acid:monoatomic cation symporter activity 1/194 29/18639 0.0344827586206897 3.31301102026306 0.261881846873476 0.503206415664734 GO:0097472 cyclin-dependent protein kinase activity 1/194 29/18639 0.0344827586206897 3.31301102026306 0.261881846873476 0.503206415664734 GO:0106222 lncRNA binding 1/194 29/18639 0.0344827586206897 3.31301102026306 0.261881846873476 0.503206415664734 GO:0008187 poly-pyrimidine tract binding 1/194 30/18639 0.0333333333333333 3.20257731958763 0.269576361742178 0.511015123437192 GO:0015215 nucleotide transmembrane transporter activity 1/194 30/18639 0.0333333333333333 3.20257731958763 0.269576361742178 0.511015123437192 GO:0031624 ubiquitin conjugating enzyme binding 1/194 30/18639 0.0333333333333333 3.20257731958763 0.269576361742178 0.511015123437192 GO:0070566 adenylyltransferase activity 1/194 30/18639 0.0333333333333333 3.20257731958763 0.269576361742178 0.511015123437192 GO:0042626 ATPase-coupled transmembrane transporter activity 2/194 98/18639 0.0204081632653061 1.96076162423732 0.271646429089621 0.513211206635761 GO:0005452 solute:inorganic anion antiporter activity 1/194 31/18639 0.032258064516129 3.09926837379448 0.277191074291053 0.516750247767758 GO:0016411 acylglycerol O-acyltransferase activity 1/194 31/18639 0.032258064516129 3.09926837379448 0.277191074291053 0.516750247767758 GO:0017147 Wnt-protein binding 1/194 31/18639 0.032258064516129 3.09926837379448 0.277191074291053 0.516750247767758 GO:0070325 lipoprotein particle receptor binding 1/194 31/18639 0.032258064516129 3.09926837379448 0.277191074291053 0.516750247767758 GO:0043130 ubiquitin binding 2/194 100/18639 0.02 1.92154639175258 0.279361881671675 0.51906587303525 GO:0043021 ribonucleoprotein complex binding 3/194 177/18639 0.0169491525423729 1.62842914555303 0.280277132154025 0.51906587303525 GO:0005319 lipid transporter activity 3/194 178/18639 0.0168539325842697 1.61928066720723 0.2831037275196 0.522581634732901 GO:0042910 xenobiotic transmembrane transporter activity 1/194 32/18639 0.03125 3.0024162371134 0.284726807931828 0.523860107403984 GO:0015171 amino acid transmembrane transporter activity 2/194 102/18639 0.0196078431372549 1.88386901152213 0.287071785826559 0.526454121890401 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/194 33/18639 0.0303030303030303 2.91143392689784 0.292184377623945 0.528938278463926 GO:0019239 deaminase activity 1/194 33/18639 0.0303030303030303 2.91143392689784 0.292184377623945 0.528938278463926 GO:0030296 protein tyrosine kinase activator activity 1/194 33/18639 0.0303030303030303 2.91143392689784 0.292184377623945 0.528938278463926 GO:0071889 14-3-3 protein binding 1/194 33/18639 0.0303030303030303 2.91143392689784 0.292184377623945 0.528938278463926 GO:0008175 tRNA methyltransferase activity 1/194 34/18639 0.0294117647058824 2.8258035172832 0.299564589960877 0.53488179861573 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/194 34/18639 0.0294117647058824 2.8258035172832 0.299564589960877 0.53488179861573 GO:0016831 carboxy-lyase activity 1/194 34/18639 0.0294117647058824 2.8258035172832 0.299564589960877 0.53488179861573 GO:0030332 cyclin binding 1/194 34/18639 0.0294117647058824 2.8258035172832 0.299564589960877 0.53488179861573 GO:0000149 SNARE binding 2/194 106/18639 0.0188679245283019 1.81277961486092 0.30246281801416 0.53488179861573 GO:0016757 glycosyltransferase activity 4/194 267/18639 0.0149812734082397 1.43936059307309 0.302758972601431 0.53488179861573 GO:0015276 ligand-gated monoatomic ion channel activity 3/194 186/18639 0.0161290322580645 1.54963418689724 0.305793220270701 0.53488179861573 GO:0019888 protein phosphatase regulator activity 2/194 107/18639 0.0186915887850467 1.79583774930147 0.306302473725138 0.53488179861573 GO:0000175 3'-5'-RNA exonuclease activity 1/194 35/18639 0.0285714285714286 2.74506627393225 0.306868243255561 0.53488179861573 GO:0005154 epidermal growth factor receptor binding 1/194 35/18639 0.0285714285714286 2.74506627393225 0.306868243255561 0.53488179861573 GO:0061631 ubiquitin conjugating enzyme activity 1/194 35/18639 0.0285714285714286 2.74506627393225 0.306868243255561 0.53488179861573 GO:0140566 histone reader activity 1/194 35/18639 0.0285714285714286 2.74506627393225 0.306868243255561 0.53488179861573 GO:0022834 ligand-gated channel activity 3/194 188/18639 0.0159574468085106 1.53314871682386 0.311480557057285 0.541245535874233 GO:0000993 RNA polymerase II complex binding 1/194 36/18639 0.0277777777777778 2.66881443298969 0.314096127624967 0.542442085438209 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/194 36/18639 0.0277777777777778 2.66881443298969 0.314096127624967 0.542442085438209 GO:0023023 MHC protein complex binding 1/194 37/18639 0.027027027027027 2.59668431317916 0.321249025073805 0.547042908930088 GO:0030551 cyclic nucleotide binding 1/194 37/18639 0.027027027027027 2.59668431317916 0.321249025073805 0.547042908930088 GO:0042805 actinin binding 1/194 37/18639 0.027027027027027 2.59668431317916 0.321249025073805 0.547042908930088 GO:1901681 sulfur compound binding 4/194 275/18639 0.0145454545454545 1.39748828491097 0.321530197936689 0.547042908930088 GO:1902936 phosphatidylinositol bisphosphate binding 2/194 111/18639 0.018018018018018 1.73112287545277 0.32161847754149 0.547042908930088 GO:0005200 structural constituent of cytoskeleton 2/194 112/18639 0.0178571428571429 1.71566642120766 0.325435213733932 0.550144346702591 GO:0043022 ribosome binding 2/194 112/18639 0.0178571428571429 1.71566642120766 0.325435213733932 0.550144346702591 GO:0042578 phosphoric ester hydrolase activity 5/194 363/18639 0.0137741046831956 1.32337905768084 0.327241410299612 0.550144346702591 GO:0042887 amide transmembrane transporter activity 1/194 38/18639 0.0263157894736842 2.52835051546392 0.32832770957739 0.550144346702591 GO:0043531 ADP binding 1/194 38/18639 0.0263157894736842 2.52835051546392 0.32832770957739 0.550144346702591 GO:0030246 carbohydrate binding 4/194 280/18639 0.0142857142857143 1.37253313696613 0.333308860701831 0.555248581719424 GO:0001221 transcription coregulator binding 2/194 115/18639 0.0173913043478261 1.67090990587181 0.336851088065486 0.555248581719424 GO:0035401 histone H3Y41 kinase activity 2/194 115/18639 0.0173913043478261 1.67090990587181 0.336851088065486 0.555248581719424 GO:0140801 histone H2AXY142 kinase activity 2/194 115/18639 0.0173913043478261 1.67090990587181 0.336851088065486 0.555248581719424 GO:0016758 hexosyltransferase activity 3/194 197/18639 0.0152284263959391 1.46310638965932 0.337095835093174 0.555248581719424 GO:0015294 solute:monoatomic cation symporter activity 2/194 116/18639 0.0172413793103448 1.65650551013153 0.340643965272744 0.555248581719424 GO:0015144 carbohydrate transmembrane transporter activity 1/194 40/18639 0.025 2.40193298969072 0.342265495994307 0.555248581719424 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/194 40/18639 0.025 2.40193298969072 0.342265495994307 0.555248581719424 GO:0030331 nuclear estrogen receptor binding 1/194 40/18639 0.025 2.40193298969072 0.342265495994307 0.555248581719424 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/194 40/18639 0.025 2.40193298969072 0.342265495994307 0.555248581719424 GO:0071949 FAD binding 1/194 40/18639 0.025 2.40193298969072 0.342265495994307 0.555248581719424 GO:0019208 phosphatase regulator activity 2/194 117/18639 0.0170940170940171 1.64234734337827 0.344430167114405 0.555248581719424 GO:0016829 lyase activity 3/194 200/18639 0.015 1.44115979381443 0.345629213944576 0.555248581719424 GO:0001727 lipid kinase activity 1/194 41/18639 0.024390243902439 2.34334925823485 0.349126106445251 0.555248581719424 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/194 41/18639 0.024390243902439 2.34334925823485 0.349126106445251 0.555248581719424 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/194 41/18639 0.024390243902439 2.34334925823485 0.349126106445251 0.555248581719424 GO:0042287 MHC protein binding 1/194 41/18639 0.024390243902439 2.34334925823485 0.349126106445251 0.555248581719424 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/194 41/18639 0.024390243902439 2.34334925823485 0.349126106445251 0.555248581719424 GO:0032182 ubiquitin-like protein binding 2/194 120/18639 0.0166666666666667 1.60128865979381 0.355746039188792 0.55972189504959 GO:0019894 kinesin binding 1/194 42/18639 0.0238095238095238 2.28755522827688 0.355915521186063 0.55972189504959 GO:0035198 miRNA binding 1/194 42/18639 0.0238095238095238 2.28755522827688 0.355915521186063 0.55972189504959 GO:0043175 RNA polymerase core enzyme binding 1/194 42/18639 0.0238095238095238 2.28755522827688 0.355915521186063 0.55972189504959 GO:0004540 RNA nuclease activity 2/194 121/18639 0.0165289256198347 1.58805486921701 0.359502889452533 0.563788653932524 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/194 43/18639 0.0232558139534884 2.23435626947974 0.362634475258758 0.563986766769836 GO:0008200 ion channel inhibitor activity 1/194 43/18639 0.0232558139534884 2.23435626947974 0.362634475258758 0.563986766769836 GO:0008375 acetylglucosaminyltransferase activity 1/194 43/18639 0.0232558139534884 2.23435626947974 0.362634475258758 0.563986766769836 GO:0001046 core promoter sequence-specific DNA binding 1/194 44/18639 0.0227272727272727 2.18357544517338 0.369283696155714 0.566503326800182 GO:0001223 transcription coactivator binding 1/194 44/18639 0.0227272727272727 2.18357544517338 0.369283696155714 0.566503326800182 GO:0016248 channel inhibitor activity 1/194 44/18639 0.0227272727272727 2.18357544517338 0.369283696155714 0.566503326800182 GO:0016790 thiolester hydrolase activity 1/194 44/18639 0.0227272727272727 2.18357544517338 0.369283696155714 0.566503326800182 GO:0019205 nucleobase-containing compound kinase activity 1/194 44/18639 0.0227272727272727 2.18357544517338 0.369283696155714 0.566503326800182 GO:0015631 tubulin binding 5/194 385/18639 0.012987012987013 1.24775739724193 0.37255958564105 0.567963377469743 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/194 45/18639 0.0222222222222222 2.13505154639175 0.375863903896816 0.567963377469743 GO:0051539 4 iron, 4 sulfur cluster binding 1/194 45/18639 0.0222222222222222 2.13505154639175 0.375863903896816 0.567963377469743 GO:0140303 intramembrane lipid transporter activity 1/194 45/18639 0.0222222222222222 2.13505154639175 0.375863903896816 0.567963377469743 GO:0141110 transporter inhibitor activity 1/194 45/18639 0.0222222222222222 2.13505154639175 0.375863903896816 0.567963377469743 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/194 46/18639 0.0217391304347826 2.08863738233976 0.382375811105809 0.567963377469743 GO:0030276 clathrin binding 1/194 46/18639 0.0217391304347826 2.08863738233976 0.382375811105809 0.567963377469743 GO:0030291 protein serine/threonine kinase inhibitor activity 1/194 46/18639 0.0217391304347826 2.08863738233976 0.382375811105809 0.567963377469743 GO:0031625 ubiquitin protein ligase binding 4/194 302/18639 0.0132450331125828 1.27254727930634 0.385243828482265 0.567963377469743 GO:0031490 chromatin DNA binding 2/194 128/18639 0.015625 1.5012081185567 0.385564613408625 0.567963377469743 GO:0001784 phosphotyrosine residue binding 1/194 47/18639 0.0212765957446809 2.04419828909849 0.388820123085881 0.567963377469743 GO:0005504 fatty acid binding 1/194 47/18639 0.0212765957446809 2.04419828909849 0.388820123085881 0.567963377469743 GO:0043495 protein-membrane adaptor activity 1/194 47/18639 0.0212765957446809 2.04419828909849 0.388820123085881 0.567963377469743 GO:0140938 histone H3 methyltransferase activity 1/194 47/18639 0.0212765957446809 2.04419828909849 0.388820123085881 0.567963377469743 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/194 130/18639 0.0153846153846154 1.47811260904044 0.392928220563958 0.567963377469743 GO:0038187 pattern recognition receptor activity 1/194 48/18639 0.0208333333333333 2.00161082474227 0.395197537894472 0.567963377469743 GO:0140693 molecular condensate scaffold activity 1/194 48/18639 0.0208333333333333 2.00161082474227 0.395197537894472 0.567963377469743 GO:0005262 calcium channel activity 2/194 131/18639 0.0152671755725191 1.46682930668136 0.396595220952296 0.567963377469743 GO:0001222 transcription corepressor binding 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0005004 GPI-linked ephrin receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0005008 hepatocyte growth factor receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0005009 insulin receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0005011 macrophage colony-stimulating factor receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0005020 stem cell factor receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0008288 boss receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0016763 pentosyltransferase activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0036332 placental growth factor receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0038062 protein tyrosine kinase collagen receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0060175 brain-derived neurotrophic factor receptor activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0060590 ATPase regulator activity 1/194 49/18639 0.0204081632653061 1.96076162423732 0.401508746417332 0.567963377469743 GO:0005006 epidermal growth factor receptor activity 1/194 50/18639 0.02 1.92154639175258 0.407754432441809 0.569556443091336 GO:0005007 fibroblast growth factor receptor activity 1/194 50/18639 0.02 1.92154639175258 0.407754432441809 0.569556443091336 GO:0005017 platelet-derived growth factor receptor activity 1/194 50/18639 0.02 1.92154639175258 0.407754432441809 0.569556443091336 GO:0005019 platelet-derived growth factor beta-receptor activity 1/194 50/18639 0.02 1.92154639175258 0.407754432441809 0.569556443091336 GO:0015605 organophosphate ester transmembrane transporter activity 1/194 50/18639 0.02 1.92154639175258 0.407754432441809 0.569556443091336 GO:0004175 endopeptidase activity 5/194 405/18639 0.0123456790123457 1.18613974799542 0.413809753614181 0.569556443091336 GO:0005010 insulin-like growth factor receptor activity 1/194 51/18639 0.0196078431372549 1.88386901152213 0.413935272729414 0.569556443091336 GO:0005030 neurotrophin receptor activity 1/194 51/18639 0.0196078431372549 1.88386901152213 0.413935272729414 0.569556443091336 GO:0016597 amino acid binding 1/194 51/18639 0.0196078431372549 1.88386901152213 0.413935272729414 0.569556443091336 GO:0016830 carbon-carbon lyase activity 1/194 51/18639 0.0196078431372549 1.88386901152213 0.413935272729414 0.569556443091336 GO:0016779 nucleotidyltransferase activity 2/194 136/18639 0.0147058823529412 1.4129017586416 0.414774674364916 0.569556443091336 GO:0019838 growth factor binding 2/194 136/18639 0.0147058823529412 1.4129017586416 0.414774674364916 0.569556443091336 GO:0030295 protein kinase activator activity 2/194 139/18639 0.0143884892086331 1.38240747608099 0.425551624965669 0.571183725695904 GO:0070851 growth factor receptor binding 2/194 139/18639 0.0143884892086331 1.38240747608099 0.425551624965669 0.571183725695904 GO:0004864 protein phosphatase inhibitor activity 1/194 53/18639 0.0188679245283019 1.81277961486092 0.426105088440994 0.571183725695904 GO:0005003 ephrin receptor activity 1/194 53/18639 0.0188679245283019 1.81277961486092 0.426105088440994 0.571183725695904 GO:0005005 transmembrane-ephrin receptor activity 1/194 53/18639 0.0188679245283019 1.81277961486092 0.426105088440994 0.571183725695904 GO:0005246 calcium channel regulator activity 1/194 53/18639 0.0188679245283019 1.81277961486092 0.426105088440994 0.571183725695904 GO:0017046 peptide hormone binding 1/194 53/18639 0.0188679245283019 1.81277961486092 0.426105088440994 0.571183725695904 GO:0038064 collagen receptor activity 1/194 53/18639 0.0188679245283019 1.81277961486092 0.426105088440994 0.571183725695904 GO:0140296 general transcription initiation factor binding 1/194 53/18639 0.0188679245283019 1.81277961486092 0.426105088440994 0.571183725695904 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/194 53/18639 0.0188679245283019 1.81277961486092 0.426105088440994 0.571183725695904 GO:0044389 ubiquitin-like protein ligase binding 4/194 322/18639 0.0124223602484472 1.19350707562272 0.432061562659071 0.575105675114726 GO:0017069 snRNA binding 1/194 54/18639 0.0185185185185185 1.77920962199313 0.432095382901472 0.575105675114726 GO:0050661 NADP binding 1/194 54/18639 0.0185185185185185 1.77920962199313 0.432095382901472 0.575105675114726 GO:0004857 enzyme inhibitor activity 5/194 416/18639 0.0120192307692308 1.15477547581285 0.436351911383012 0.578890172579453 GO:0008374 O-acyltransferase activity 1/194 55/18639 0.0181818181818182 1.74686035613871 0.438023469838094 0.578890172579453 GO:0140313 molecular sequestering activity 1/194 55/18639 0.0181818181818182 1.74686035613871 0.438023469838094 0.578890172579453 GO:0019903 protein phosphatase binding 2/194 144/18639 0.0138888888888889 1.33440721649485 0.4432816164644 0.581186198757069 GO:0019955 cytokine binding 2/194 144/18639 0.0138888888888889 1.33440721649485 0.4432816164644 0.581186198757069 GO:0019212 phosphatase inhibitor activity 1/194 56/18639 0.0178571428571429 1.71566642120766 0.443889991945897 0.581186198757069 GO:0170055 lipid transmembrane transporter activity 1/194 56/18639 0.0178571428571429 1.71566642120766 0.443889991945897 0.581186198757069 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/194 57/18639 0.0175438596491228 1.68556701030928 0.449695585314163 0.58683528742083 GO:0015293 symporter activity 2/194 146/18639 0.0136986301369863 1.31612766558396 0.450289243633745 0.58683528742083 GO:0015085 calcium ion transmembrane transporter activity 2/194 147/18639 0.0136054421768707 1.30717441615822 0.453774455868909 0.590011590425395 GO:0008408 3'-5' exonuclease activity 1/194 58/18639 0.0172413793103448 1.65650551013153 0.455440879493964 0.590813859804382 GO:0019209 kinase activator activity 2/194 148/18639 0.0135135135135135 1.29834215658958 0.457247105068494 0.59137635109135 GO:0015459 potassium channel regulator activity 1/194 59/18639 0.0169491525423729 1.62842914555303 0.461126497565013 0.59137635109135 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/194 59/18639 0.0169491525423729 1.62842914555303 0.461126497565013 0.59137635109135 GO:0036002 pre-mRNA binding 1/194 59/18639 0.0169491525423729 1.62842914555303 0.461126497565013 0.59137635109135 GO:0045309 protein phosphorylated amino acid binding 1/194 59/18639 0.0169491525423729 1.62842914555303 0.461126497565013 0.59137635109135 GO:0001098 basal transcription machinery binding 1/194 60/18639 0.0166666666666667 1.60128865979381 0.466753056201848 0.595877484448164 GO:0001099 basal RNA polymerase II transcription machinery binding 1/194 60/18639 0.0166666666666667 1.60128865979381 0.466753056201848 0.595877484448164 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/194 61/18639 0.0163934426229508 1.5750380260267 0.472321165739328 0.600263693704834 GO:0019905 syntaxin binding 1/194 61/18639 0.0163934426229508 1.5750380260267 0.472321165739328 0.600263693704834 GO:0140104 molecular carrier activity 3/194 249/18639 0.0120481927710843 1.15755806732083 0.4812422528762 0.610223847678605 GO:1901682 sulfur compound transmembrane transporter activity 1/194 63/18639 0.0158730158730159 1.52503681885125 0.483284447545648 0.611436278580224 GO:0140375 immune receptor activity 2/194 156/18639 0.0128205128205128 1.2317605075337 0.484562786696857 0.611679033431234 GO:0038024 cargo receptor activity 1/194 65/18639 0.0153846153846154 1.47811260904044 0.494021101316701 0.620204473061097 GO:0160215 deacylase activity 1/194 65/18639 0.0153846153846154 1.47811260904044 0.494021101316701 0.620204473061097 GO:0005216 monoatomic ion channel activity 5/194 448/18639 0.0111607142857143 1.07229151325479 0.500642554047215 0.620204473061097 GO:0004866 endopeptidase inhibitor activity 2/194 161/18639 0.0124223602484472 1.19350707562272 0.501200106404428 0.620204473061097 GO:0005178 integrin binding 2/194 161/18639 0.0124223602484472 1.19350707562272 0.501200106404428 0.620204473061097 GO:0061630 ubiquitin protein ligase activity 4/194 353/18639 0.0113314447592068 1.08869483951987 0.502510765698245 0.620204473061097 GO:0004842 ubiquitin-protein transferase activity 5/194 449/18639 0.0111358574610245 1.06990333616513 0.50261038979425 0.620204473061097 GO:0008083 growth factor activity 2/194 162/18639 0.0123456790123457 1.18613974799542 0.504486234121567 0.620204473061097 GO:0008173 RNA methyltransferase activity 1/194 67/18639 0.0149253731343284 1.43398984459148 0.504535788031941 0.620204473061097 GO:0016500 protein-hormone receptor activity 1/194 67/18639 0.0149253731343284 1.43398984459148 0.504535788031941 0.620204473061097 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/194 67/18639 0.0149253731343284 1.43398984459148 0.504535788031941 0.620204473061097 GO:0042054 histone methyltransferase activity 1/194 67/18639 0.0149253731343284 1.43398984459148 0.504535788031941 0.620204473061097 GO:0003777 microtubule motor activity 1/194 68/18639 0.0147058823529412 1.4129017586416 0.509711324168156 0.622489100882152 GO:0030145 manganese ion binding 1/194 68/18639 0.0147058823529412 1.4129017586416 0.509711324168156 0.622489100882152 GO:1990841 promoter-specific chromatin binding 1/194 68/18639 0.0147058823529412 1.4129017586416 0.509711324168156 0.622489100882152 GO:0015081 sodium ion transmembrane transporter activity 2/194 164/18639 0.0121951219512195 1.17167462911743 0.511016577278483 0.622732322527675 GO:0002039 p53 binding 1/194 69/18639 0.0144927536231884 1.39242492155984 0.514833073299134 0.623688954691465 GO:0016279 protein-lysine N-methyltransferase activity 1/194 69/18639 0.0144927536231884 1.39242492155984 0.514833073299134 0.623688954691465 GO:0003730 mRNA 3'-UTR binding 3/194 262/18639 0.0114503816793893 1.10012198001102 0.515124980340198 0.623688954691465 GO:0015399 primary active transmembrane transporter activity 2/194 166/18639 0.0120481927710843 1.15755806732083 0.517490606419953 0.624778335389605 GO:0022804 active transmembrane transporter activity 5/194 457/18639 0.0109409190371991 1.05117417491935 0.518244196495463 0.624778335389605 GO:0016278 lysine N-methyltransferase activity 1/194 70/18639 0.0142857142857143 1.37253313696613 0.519901591542535 0.625069672283537 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/194 167/18639 0.0119760479041916 1.15062658188777 0.520706352221988 0.625069672283537 GO:0030414 peptidase inhibitor activity 2/194 169/18639 0.0118343195266272 1.13700969926188 0.527095028290311 0.631392555164777 GO:0005518 collagen binding 1/194 72/18639 0.0138888888888889 1.33440721649485 0.529881131294776 0.632617310220552 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/194 268/18639 0.0111940298507463 1.07549238344361 0.53036477872842 0.632617310220552 GO:0003684 damaged DNA binding 1/194 74/18639 0.0135135135135135 1.29834215658958 0.539654279011526 0.642336911381583 GO:0016791 phosphatase activity 3/194 273/18639 0.010989010989011 1.05579472074317 0.542860148286459 0.642628248950542 GO:0061659 ubiquitin-like protein ligase activity 4/194 372/18639 0.010752688172043 1.03308945793149 0.543786640052819 0.642628248950542 GO:0003725 double-stranded RNA binding 1/194 75/18639 0.0133333333333333 1.28103092783505 0.544464786411028 0.642628248950542 GO:0019003 GDP binding 1/194 75/18639 0.0133333333333333 1.28103092783505 0.544464786411028 0.642628248950542 GO:0051536 iron-sulfur cluster binding 1/194 76/18639 0.0131578947368421 1.26417525773196 0.549225281532568 0.646890865068694 GO:0003724 RNA helicase activity 1/194 77/18639 0.012987012987013 1.24775739724193 0.553936281660924 0.649721097031459 GO:0051540 metal cluster binding 1/194 77/18639 0.012987012987013 1.24775739724193 0.553936281660924 0.649721097031459 GO:0001217 DNA-binding transcription repressor activity 3/194 278/18639 0.0107913669064748 1.03680560706074 0.555163298276425 0.649806521683216 GO:0019787 ubiquitin-like protein transferase activity 5/194 479/18639 0.0104384133611691 1.00289477648882 0.560127001628254 0.654256228042961 GO:0008186 ATP-dependent activity, acting on RNA 1/194 79/18639 0.0126582278481013 1.21616860237505 0.563211839517808 0.655141044728359 GO:0033293 monocarboxylic acid binding 1/194 79/18639 0.0126582278481013 1.21616860237505 0.563211839517808 0.655141044728359 GO:0000049 tRNA binding 1/194 80/18639 0.0125 1.20096649484536 0.567777405419399 0.659090060311591 GO:0030971 receptor tyrosine kinase binding 1/194 81/18639 0.0123456790123457 1.18613974799542 0.572295492781253 0.662603133312426 GO:0061135 endopeptidase regulator activity 2/194 184/18639 0.0108695652173913 1.04431869116988 0.573157594890145 0.662603133312426 GO:0140098 catalytic activity, acting on RNA 4/194 387/18639 0.0103359173126615 0.993047230879885 0.575109379918994 0.662740858554249 GO:0015291 secondary active transmembrane transporter activity 3/194 287/18639 0.0104529616724739 1.00429253924351 0.576808207267463 0.662740858554249 GO:0019207 kinase regulator activity 3/194 287/18639 0.0104529616724739 1.00429253924351 0.576808207267463 0.662740858554249 GO:0001540 amyloid-beta binding 1/194 83/18639 0.0120481927710843 1.15755806732083 0.581191191670867 0.664605263054557 GO:0008135 translation factor activity, RNA binding 1/194 83/18639 0.0120481927710843 1.15755806732083 0.581191191670867 0.664605263054557 GO:0031406 carboxylic acid binding 2/194 187/18639 0.0106951871657754 1.02756491537571 0.58197228185772 0.664605263054557 GO:0004860 protein kinase inhibitor activity 1/194 84/18639 0.0119047619047619 1.14377761413844 0.585569770503366 0.666011678370495 GO:0180051 translation factor activity 1/194 84/18639 0.0119047619047619 1.14377761413844 0.585569770503366 0.666011678370495 GO:0043177 organic acid binding 2/194 189/18639 0.0105820105820106 1.0166912125675 0.587774434080905 0.667171383845865 GO:0019902 phosphatase binding 2/194 190/18639 0.0105263157894737 1.01134020618557 0.590653191990954 0.668394460561372 GO:0016755 aminoacyltransferase activity 5/194 496/18639 0.0100806451612903 0.968521366810775 0.59122636120704 0.668394460561372 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/194 88/18639 0.0113636363636364 1.09178772258669 0.602633336304983 0.679924986652717 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/194 89/18639 0.0112359550561798 1.07952044480482 0.606788860684091 0.681880496138011 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/194 89/18639 0.0112359550561798 1.07952044480482 0.606788860684091 0.681880496138011 GO:0019210 kinase inhibitor activity 1/194 90/18639 0.0111111111111111 1.06752577319588 0.610901149688258 0.683772062175923 GO:0140793 histone H2AXY142 phosphatase activity 1/194 90/18639 0.0111111111111111 1.06752577319588 0.610901149688258 0.683772062175923 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/194 91/18639 0.010989010989011 1.05579472074317 0.61497065084522 0.686961262749719 GO:0043178 alcohol binding 1/194 92/18639 0.0108695652173913 1.04431869116988 0.618997807074248 0.6900906245204 GO:0051219 phosphoprotein binding 1/194 93/18639 0.010752688172043 1.03308945793149 0.622983056733363 0.693160990001745 GO:0008168 methyltransferase activity 2/194 204/18639 0.00980392156862745 0.941934505761067 0.62939329633866 0.698912082522023 GO:0008276 protein methyltransferase activity 1/194 95/18639 0.0105263157894737 1.01134020618557 0.630829567247549 0.699128044016476 GO:0004896 cytokine receptor activity 1/194 96/18639 0.0104166666666667 1.00080541237113 0.634691682430572 0.702026359937941 GO:0004725 protein tyrosine phosphatase activity 1/194 98/18639 0.0102040816326531 0.980380812118662 0.642295735571102 0.706526213096748 GO:0008170 N-methyltransferase activity 1/194 98/18639 0.0102040816326531 0.980380812118662 0.642295735571102 0.706526213096748 GO:0004518 nuclease activity 2/194 209/18639 0.00956937799043062 0.919400187441424 0.642524726652816 0.706526213096748 GO:0022836 gated channel activity 3/194 318/18639 0.00943396226415094 0.906389807430461 0.646163019597758 0.709141871410405 GO:0016741 transferase activity, transferring one-carbon groups 2/194 215/18639 0.00930232558139535 0.893742507791896 0.65779773464422 0.720506078997463 GO:0061134 peptidase regulator activity 2/194 226/18639 0.00884955752212389 0.850241766262202 0.684443481794545 0.747092479698348 GO:0004222 metalloendopeptidase activity 1/194 110/18639 0.00909090909090909 0.873430178069353 0.684724190984632 0.747092479698348 GO:0046873 metal ion transmembrane transporter activity 4/194 450/18639 0.00888888888888889 0.854020618556701 0.692392615995259 0.753969104610079 GO:0000287 magnesium ion binding 2/194 230/18639 0.00869565217391304 0.835454952935903 0.693705144206076 0.753969104610079 GO:0017124 SH3 domain binding 1/194 115/18639 0.00869565217391304 0.835454952935903 0.700888691108202 0.760308926963232 GO:0009055 electron transfer activity 1/194 116/18639 0.00862068965517241 0.828252755065766 0.704021253941554 0.762238396094413 GO:1990782 protein tyrosine kinase binding 1/194 117/18639 0.00854700854700855 0.821173671689136 0.707121177103857 0.764125187542172 GO:0033218 amide binding 2/194 247/18639 0.00809716599190283 0.777954004758128 0.730599600451131 0.78798386025668 GO:0042826 histone deacetylase binding 1/194 127/18639 0.0078740157480315 0.756514327461645 0.736397963462815 0.792719031414082 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/194 128/18639 0.0078125 0.75060405927835 0.739160430786076 0.794174279642292 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/194 130/18639 0.00769230769230769 0.739056304520222 0.744599257806171 0.798494061228332 GO:0019887 protein kinase regulator activity 2/194 255/18639 0.00784313725490196 0.753547604608854 0.746624261036645 0.799143458105763 GO:0005179 hormone activity 1/194 132/18639 0.00757575757575758 0.727858481724461 0.749925250993761 0.801153541384227 GO:0051087 protein-folding chaperone binding 1/194 134/18639 0.00746268656716418 0.716994922295738 0.755140739319947 0.805197417115777 GO:0015297 antiporter activity 1/194 135/18639 0.00740740740740741 0.711683848797251 0.757707758859095 0.806407312358546 GO:0140789 histone phosphatase activity 1/194 136/18639 0.00735294117647059 0.706450879320801 0.760248003929423 0.8075842004005 GO:0140101 catalytic activity, acting on a tRNA 1/194 139/18639 0.00719424460431655 0.691203738040496 0.767710856321571 0.813975917342833 GO:0008194 UDP-glycosyltransferase activity 1/194 145/18639 0.00689655172413793 0.662602204052613 0.781950267496622 0.827515038722929 GO:0008017 microtubule binding 2/194 276/18639 0.0072463768115942 0.696212460779919 0.784857751755865 0.829033610203663 GO:0000510 H3-H4 histone complex chaperone activity 1/194 151/18639 0.00662251655629139 0.636273639653171 0.795321020992082 0.832109953773271 GO:0140584 chromatin extrusion motor activity 1/194 151/18639 0.00662251655629139 0.636273639653171 0.795321020992082 0.832109953773271 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/194 151/18639 0.00662251655629139 0.636273639653171 0.795321020992082 0.832109953773271 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/194 151/18639 0.00662251655629139 0.636273639653171 0.795321020992082 0.832109953773271 GO:0015616 DNA translocase activity 1/194 152/18639 0.00657894736842105 0.632087628865979 0.797468777478859 0.832109953773271 GO:0140674 ATP-dependent histone chaperone activity 1/194 152/18639 0.00657894736842105 0.632087628865979 0.797468777478859 0.832109953773271 GO:0003774 cytoskeletal motor activity 1/194 153/18639 0.0065359477124183 0.627956337174045 0.799594111885151 0.832109953773271 GO:0061775 cohesin loader activity 1/194 153/18639 0.0065359477124183 0.627956337174045 0.799594111885151 0.832109953773271 GO:0004386 helicase activity 1/194 155/18639 0.00645161290322581 0.619853674758896 0.803778443574262 0.834921150797619 GO:0140658 ATP-dependent chromatin remodeler activity 1/194 158/18639 0.00632911392405063 0.608084301187524 0.809892519844234 0.839722815234445 GO:0003689 DNA clamp loader activity 1/194 160/18639 0.00625 0.60048324742268 0.813862896388203 0.842288254901762 GO:0001664 G protein-coupled receptor binding 2/194 297/18639 0.00673400673400673 0.64698531708841 0.817951875948325 0.844966800291572 GO:0140713 histone chaperone activity 1/194 164/18639 0.00609756097560976 0.585837314558713 0.821557847934154 0.847137487888147 GO:0016874 ligase activity 1/194 167/18639 0.00598802395209581 0.575313290943885 0.827120615116635 0.851314271134672 GO:0003823 antigen binding 1/194 174/18639 0.00574712643678161 0.552168503377177 0.839438565876946 0.862415898884527 GO:0004721 phosphoprotein phosphatase activity 1/194 175/18639 0.00571428571428571 0.549013254786451 0.841125482650294 0.862574948510229 GO:0008237 metallopeptidase activity 1/194 184/18639 0.00543478260869565 0.522159345584939 0.855535861186179 0.875757617905125 GO:0140597 protein carrier chaperone 1/194 188/18639 0.00531914893617021 0.511049572274622 0.861515687111534 0.879163653576737 GO:0003924 GTPase activity 2/194 331/18639 0.00604229607250755 0.580527610801383 0.861986388586783 0.879163653576737 GO:0005261 monoatomic cation channel activity 2/194 341/18639 0.00586510263929619 0.563503340689905 0.872957699432794 0.888743552948758 GO:0008094 ATP-dependent activity, acting on DNA 1/194 210/18639 0.00476190476190476 0.457511045655376 0.890263297275695 0.904726058422774 GO:0046982 protein heterodimerization activity 2/194 369/18639 0.00542005420054201 0.520744279607745 0.899559944227125 0.912526574053822 GO:0005525 GTP binding 2/194 378/18639 0.00529100529100529 0.508345606283751 0.906949002743588 0.91836742544 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/194 229/18639 0.00436681222707424 0.419551613919777 0.910260228290054 0.920065544932317 GO:0019001 guanyl nucleotide binding 2/194 400/18639 0.005 0.480386597938144 0.922933705577873 0.929537882361973 GO:0032561 guanyl ribonucleotide binding 2/194 400/18639 0.005 0.480386597938144 0.922933705577873 0.929537882361973 GO:0005126 cytokine receptor binding 1/194 275/18639 0.00363636363636364 0.349372071227741 0.944907936431446 0.949969943233757 GO:0030371 translation repressor activity 1/194 329/18639 0.00303951367781155 0.292028327014069 0.968978718344967 0.972433187929085 GO:0140097 catalytic activity, acting on DNA 1/194 336/18639 0.00297619047619048 0.28594440353461 0.971207977333016 0.972936105406563 GO:0045182 translation regulator activity 1/194 356/18639 0.00280898876404494 0.269880111201205 0.976736898043056 0.976736898043056